Exhibit 31.2




CERTIFICATIONS


I, Frank
Cesario, certify that:




1. I have
reviewed this annual report on Form 10-K of ISCO International,
Inc.;




2. Based
on my knowledge, this annual report does not contain any untrue statement of a
material fact or omit to state a material fact necessary to make the statements
made, in light of the circumstances under which such statements were made, not
misleading with respect to the period covered by this annual
report;




3. Based
on my knowledge, the financial statements, and other financial information
included in this annual report, fairly present in all material respects the
financial condition, results of operations and cash flows of the registrant as
of, and for, the periods presented in this annual report;




4. The
registrant’s other certifying officer and I are responsible for establishing and
maintaining disclosure controls and procedures (as defined in Exchange Act Rules
13a-15(e) and 15(d)-15(e)) and internal control over financial reporting (as
defined in Exchange Act Rules, 13(a)-15(f) and 15(d)-15(f)) for the registrant
and have:




a.
designed such disclosure controls and procedures or caused such disclosure
controls and procedures to be designed under our supervision to ensure that
material information relating to the registrant, including its consolidated
subsidiaries, is made known to us by others within those entities, particularly
during the period in which this annual report is being prepared;





b.
designed such internal control over financial reporting, or caused such internal
control over financial reporting to be designed under our supervision, to
provide reasonable assurance regarding the reliability of financial reporting
and the preparation of financial statements for external purposes in accordance
with generally accepted accounting principles;




c.
evaluated the effectiveness of the registrant’s disclosure controls and
procedures and presented in this annual report our conclusions about the
effectiveness of the disclosure controls and procedures, as of the end of the
period covered by this annual report based on such evaluation;




d.
disclosed in this annual report any change in the registrant’s internal control
over financial reporting that occurred during the registrant’s most recent
fiscal quarter that was materially affected, or is reasonably likely to
materially affect, the registrant’s internal control over financial reporting;
and




5. The
registrant’s other certifying officer and I have disclosed, based on our most
recent evaluation of internal control over financial reporting, to the
registrant’s auditors and the Audit Committee of the registrant’s board of
directors (or persons performing the equivalent functions):




a. all
significant deficiencies and material weaknesses in the design or operation of
internal control over financial reporting which are reasonably likely to
adversely affect the registrant’s ability to record, process, summarize and
report financial information; and




b. any
fraud, whether or not material, that involves management or other employees who
have a significant role in the registrant’s internal control over financial
reporting.






ISCO
      International,  Inc.Date: March
      28, 2008
            By:
            /s/ 
      FRANK
      CESARIOFrank
      CesarioChief
      Financial Officer