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| Delaware                        |   | 14-1745197          |
|---------------------------------|--------|---------------------|
| (State or other jurisdiction of |   | (I.R.S. Employer    |
| incorporation or organization)  |   | Identification No.) |

| 12 Bow Street, Cambridge,                |   |       |
|------------------------------------------|--------|------------|
| Massachusetts                            |   | 02138      |
| (Address of principal executive offices) |   | (Zip Code) |

| Large accelerated filer   ̈ | Accelerated Filer   ̈ | Non-accelerated filer   ̈ | Smaller reporting company  x |
|-------------------------------------------|-------------------------------------|-----------------------------------------|----------------------------------------|

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|                            |   |   |   | Director       |   | Position with                                              |
|---------------------------------|--------|--------|--------|----------------|--------|------------------------------------------------------------|
| Name                            |   | Age    |   | Since          |   | Company                                                    |
|                            |   |   |   |           |   |                                                       |
| John Alam, M.D                  |   | 52     |   | September 2011 |   | Director                                                   |
| John L. Brooks III              |   | 63     |   | September 2011 |   | Director                                                   |
| Zen Chu                         |   | 42     |   | September 2011 |   | Director                                                   |
| Richard L. Franklin, M.D., Ph.D |   | 68     |   | December 2000  |   | Chief Executive Officer, President, Secretary and Director |
| Joerg Gruber                    |   | 53     |   | April 2007     |   | Chairman of the Board                                      |
| Brock Reeve                     |   | 56     |   | September 2011 |   | Director                                                   |

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| Name and Principal Position                        |   | Year   |   | Salary($) |    |   | Stock Awards($) |   |   | All Other Compensation ($) |   |   | Total ($) |   |
|----------------------------------------------------|--------|--------|--------|-----------|---------|--------|-----------------|--------|--------|---------------------------------|--------|--------|-----------|--------|
|                                               |   |   |   |      |    |   |            |   |   |                            |   |   |      |   |
| Richard L. Franklin, MD                            |   | 2013   |   |      | 0       |   |            |   | 0      |                            |   |   | 120,000   | (1)    |   |   | 120,000 |   |
| Chief Executive Officer, President & Secretary |   | 2012   |   |      | 0       |   |            |   | 0      |                            |   |   | 170,000   | (1)    |   |   | 170,000 |   |
|                                               |   |   |   |      |    |   |            |   |   |                            |   |   |      |   |   |   |   |   |
| John M. Benson                                     |   | 2013   |   |      | 112,700 |   |            |   | 0      |                            |   |   | 4,500     | (2)    |   |   | 117,200 |   |
| CFO & Treasurer                                |   | 2012   |   |      | 110,300 |   |            |   | 0      |                            |   |   | 4,400     | (2)    |   |   | 114,700 |   |

| (1) | Represents consulting fees. |
|-----|-----------------------------|

| (2) | Represents 401(k) retirement plan account contributions made by the Company for Mr. Benson’s benefit. |
|-----|-------------------------------------------------------------------------------------------------------------|

----

| Name                    |   | Number of Securities Underlying Unexercised Options (#) Exercisable |      |   | Number of Securities Underlying Unexercised Options (#) Unexercisable |   |    | Equity Incentive Plan Awards: Number of Securities Underlying Unexercised Unearned Options (#) |   |   | Options Exercise Price ($) |   | Option Expiration Date |
|-------------------------|--------|---------------------------------------------------------------------|-----------|--------|-----------------------------------------------------------------------|--------|---------|------------------------------------------------------------------------------------------------|--------|--------|----------------------------|--------|------------------------|
|                    |   |                                                                |      |   |                                                                  |   |    |                                                                                           |   |   |                       |   |                   |
| Richard L. Franklin, MD |   |                                                                | 75,000    |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   | 0.80 |   | 5/08/2016 |
|                    |   |                                                                | 65,000    |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   | 0.85 |   | 4/23/2017 |
|                    |   |                                                                | 65,000    |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   | 0.49 |   | 4/25/2018 |
|                    |   |                                                                | 2,449,987 |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   | 0.05 |   | 12/15/2015 |
|                    |   |                                                                | 2,654,987 |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   |   |   |   |
|                    |   |                                                                |      |   |                                                                  |   |    |                                                                                           |   |   |                       |   |                   |   |   |   |   |
| John M. Benson          |   |                                                                | 150,000   |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   | 1.16 |   | 9/11/2016 |
|                    |   |                                                                | 100,000   |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   | 0.80 |   | 2/16/2017 |
|                    |   |                                                                | 100,000   |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   | 0.41 |   | 1/18/2018 |
|                    |   |                                                                | 50,000    |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   | 0.10 |   | 2/23/2019 |
|                    |   |                                                                | 62,500    |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   | 0.13 |   | 1/17/2020 |
|                    |   |                                                                | 100,000   |   |                                                                  |   | -       |                                                                                           |   |   | -                          |   |                   |   | 0.11 |   | 2/28/2020 |
|                    |   |                                                                | 750,000   |   |                                                                  |   | 250,000 | (1)                                                                                            |   |   | -                          |   |                   |   | 0.05 |   | 9/16/2021 |
|                    |   |                                                                | 1,312,500 |   |                                                                  |   | 250,000 |                                                                                           |   |   |                       |   |                   |   |   |   |   |

| (1) | These stock options vest and become exercisable in September 2014. |
|-----|--------------------------------------------------------------------|

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| Name               |   | Fee Earned orPaid in Cash ($) |   |   | Stock Awards($) |   |   | Total ($) |   |
|--------------------|--------|-------------------------------|--------|--------|-----------------|--------|--------|-----------|--------|
|               |   |                          |   |   |            |   |   |      |   |
| Joerg Gruber       |   |                          | 20,000 |   |            |   | 0      |      |   |   | 20,0000 |   |
|               |   |                          |   |   |            |   |   |      |   |   |   |   |
| John Alam, M.D.    |   |                          | 20,000 |   |            |   | 0      |      |   |   | 20,000 |   |
|               |   |                          |   |   |            |   |   |      |   |   |   |   |
| John L. Brooks III |   |                          | 20,000 |   |            |   | 0      |      |   |   | 20,000 |   |
|               |   |                          |   |   |            |   |   |      |   |   |   |   |
| Zen Chu            |   |                          | 20,000 |   |            |   | 0      |      |   |   | 20,000 |   |
|               |   |                          |   |   |            |   |   |      |   |   |   |   |
| Brock Reeve        |   |                          | 20,000 |   |            |   | 0      |      |   |   | 20,000 |   |

| Name of Beneficial Owner or Number in Group                 |   | Shares of Common Stock Beneficially Owned (1) |        |   | Percent of Class |   |
|-------------------------------------------------------------|--------|-----------------------------------------------|-------------|--------|------------------|--------|
|                                                        |   |                                          |        |   |             |   |
| Breisgau Bio Ventures S.A.                                  |   |                                          | 305,498,879 | (2)    |             |   | 42.6 |   |
| GU Holdings Limited                                         |   |                                          | 63,524,929  | (3)    |             |   | 9.5 |   |
| Richard L. Franklin                                         |   |                                          | 46,556,781  | (4)    |             |   | 7.0 |   |
| Joerg Gruber                                                |   |                                          | 59,363,033  | (5)    |             |   | 8.8 |   |
| Paul Shiels (6)                                             |   |                                          | 38,114,957  |   |             |   | 5.7 |   |
| John Benson                                                 |   |                                          | 1,388,333   | (7)    |             |   | * |   |
| Brock Reeve                                                 |   |                                          | 602,636     | (8)    |             |   | * |   |
| John Brooks                                                 |   |                                          | 602,636     | (8)    |             |   | * |   |
| Zen Chu                                                     |   |                                          | 602,636     | (8)    |             |   | * |   |
| John Alam                                                   |   |                                          | 602,636     | (8)    |             |   | * |   |
| All executive officers and directors as a group (7 persons) |   |                                          | 109,718,690 | (9)    |             |   | 16.1 |   |

----

----

| Plan Category                                              |   | Number of securities to be issued upon exercise of outstanding options, warrants and rights |       |   | Weighted average exercise price of outstanding options, warrants and rights |   |   | Number of securities remaining available for future issuance |   |
|------------------------------------------------------------|--------|---------------------------------------------------------------------------------------------|------------|--------|-----------------------------------------------------------------------------|--------|--------|--------------------------------------------------------------|--------|
|                                                       |   |                                                                                        |       |   |                                                                        |   |   |                                                         |   |
| Equity compensation plans approved by security holders     |   |                                                                                        | 19,714,000 | (1)    |                                                                        | $      | 0.12   |                                                         |   |   | 5,286,000 |   |
|                                                       |   |                                                                                        |       |   |                                                                        |   |   |                                                         |   |   |   |   |
| Equity compensation plans not approved by security holders |   |                                                                                        | 688,000    |   |                                                                        | $      | 0.46   |                                                         |   |   | 0 |   |
|                                                       |   |                                                                                        |       |   |                                                                        |   |   |                                                         |   |   |   |   |
| Total                                                      |   |                                                                                        | 20,402,000 |   |                                                                        | $      | 0.13   |                                                         |   |   | 5,286,000 |   |

|   | (1) | Includes an aggregate of 14,061,410 shares of common stock underlying stock options assumed in connection with the merger with Pathfinder, LLC and replaced with stock options under the Company’s 2006 Stock Option Plan.  The weighted average exercise price of such stock options is $.05 per share. |
|--------|-----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|               |   | 2013   |   |   | 2012   |   |
|--------------------|--------|--------|--------|--------|--------|--------|
| Audit Fees         |   | $      | 78,559 |   |   | $      | 75,500 |   |
| Audit-related Fees |   |   | -      |   |   |   | - |   |
| Tax Fees           |   |   | -      |   |   |   | - |   |
| Other Fees         |   |   | -      |   |   |   | - |   |

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| 2.1    | Agreement and Plan of Merger, dated as of December 22, 2010, by and among Registrant, SYMD Acquisition Sub, Inc., a wholly-owned subsidiary of Registrant, and Pathfinder, LLC, as amended.  (Incorporated by reference to Annex A of the definitive proxy statement on Schedule 14A filed by Registrant with the Securities and Exchange Commission on July 26, 2011.) |
|--------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 3.1    | Restated Certificate of Incorporation of Registrant, filed December 26, 1991, as amended. (Incorporated by reference to the Registrant’s Registration Statement on Form S-1 (Reg. No. 33-94008) declared effective on September 22, 1992.)                                                                                                                                  |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 3.1(a) | Amendment to Restated Certificate of Incorporation, dated August 21, 1992. (Incorporated by reference to the Registrant’s Registration Statement on Form S-1 (Reg. No. 33-94008) declared effective on September 22, 1992.)                                                                                                                                                 |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 3.1(b) | Amendment to Restated Certificate of Incorporation, dated April 22, 2005. (Incorporated by reference to the Registrant’s report on Form 10-KSB for the year ended December 31, 2006.)                                                                                                                                                                                       |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 3.1(c) | Amendment to Restated Certificate of Incorporation, dated April 27, 2006. (Incorporated by reference to the Registrant’s report on Form 10-QSB for the quarter ended March 31, 2006.)                                                                                                                                                                                       |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 3.1(d) | Amendment to the Restated Certificate of Incorporation of Registrant, as filed with the State of Delaware on September 1, 2011.  (Incorporated by reference to the Registrant’s report on Form 8-K filed September 9, 2011).                                                                                                                                      |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 3.2    | By-Laws of Registrant. (Incorporated by reference to the Registrant’s Registration Statement on Form S-1 (Reg. No. 33-94008) declared effective on September 22, 1992.)                                                                                                                                                                                                     |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 3.2(a) | Amendment to By-Laws of Registrant, adopted September 29, 2011. (Incorporated by reference to the Registrant’s report on Form 10-K for the year ended December 31, 2011, filed with the Securities and Exchange Commission on March 30, 2012.)                                                                                                                              |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 3.3    | Certificate of Designations of Series D Junior Participating Preferred Stock of the Registrant. (Incorporated by reference to the Registrant’s report on Form 8-K filed in May 2008.)                                                                                                                                                                                       |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 3.4    | Certificate of Elimination of Series A Convertible Preferred Stock, Series B Convertible Preferred Stock  and Series C Convertible Preferred Stock. (Incorporated by reference to the Registrant’s report on Form 8-K filed in May 2008.)                                                                                                                         |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 10.1   | The Registrant’s 2000 Stock Option Plan. (Incorporated by reference to the Registrant’s report on Form 8-K filed in May 2008.)                                                                                                                                                                                                                                        |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 10.2   | Agreement, dated December 1, 2011, between Registrant and Yissum Research Development Company of the Hebrew University of Jerusalem. (Incorporated by reference to the Registrant’s report on Form 10-K for the year ended December 31, 2011, filed with the Securities and Exchange Commission on March 30, 2012.)                                                         |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 10.3   | Form of Indemnification Agreement entered into between Registrant and certain officers and directors of Registrant. (Incorporated by reference to Registrant’s Registration Statement on Form S-1 (Reg. No. 333-02588) declared effective on May 3, 1996.)                                                                                                                  |
|   |                                                                                                                                                                                                                                                                                                                                                                              |
| 10.4   | 2001 Non-Qualified Stock Option Plan including form of Stock Option Agreement. (Incorporated by reference to the Registrant’s report on Form 10-K for the year ended December 31, 2001.)                                                                                                                                                                                    |

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| 10.5    | Consulting Agreement dated October 1, 2008 between the Registrant and Richard L. Franklin, MD. (Incorporated by reference to the Registrant’s report on Form 10-Q for the quarter ended September 30, 2008.) (2)                         |
|---------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|    |                                                                                                                                                                                                                                           |
| 10.5(a) | Compensation arrangement with Dr. Richard L. Franklin, MD. (Incorporated by reference to Item 5.02(c) of the Registrant’s report on Form 8-K filed with the Securities and Exchange Commission on September 9, 2011.)(2)                 |
|    |                                                                                                                                                                                                                                           |
| 10.6    | The Registrant’s 2006 Stock Option Plan, as amended. (Incorporated by reference to the Registrant’s report on Form 10-K for the year ended December 31, 2011 filed with the Securities and Exchange Commission on March 30, 2012.) |
|    |                                                                                                                                                                                                                                           |
| 10.7    | Form of ISO and Non-Qualified Stock Option Agreements under the Registrant’s 2006 Stock Option Plan. (Incorporated by reference to the Registrant’s report on Form 10-KSB for the year ended December 31, 2006.)                   |

| 10.8    | Research Agreement dated March 23, 2009 between The University Court of the University of Glasgow and Pathfinder, LLC. (Incorporated by reference to Registrant’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2011, filed with the Securities and Exchange Commission on November 21, 2011.)                             |
|---------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|    |                                                                                                                                                                                                                                                                                                                                                 |
| 10.8(a) | Extension No. 3 to Research Agreement dated March 23, 2009 between The University Court of the University of Glasgow and Pathfinder, LLC. (Incorporated by reference to the Registrant’s report on Form 10-K/A for the year ended December 31, 2012 filed with the Securities and Exchange Commission on April 30, 2013.)                      |
|    |                                                                                                                                                                                                                                                                                                                                                 |
| 10.9    | License Agreement dated March 23, 2009 between The University Court of the University of Glasgow and Pathfinder, LLC. (Incorporated by reference to Registrant’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2011, filed with the Securities and Exchange Commission on November 21, 2011.)                              |
|    |                                                                                                                                                                                                                                                                                                                                                 |
| 10.10   | Form of broker warrant issued for an aggregate of 6,276,306 shares to Clubb Capital Limited or its designees in connection with the Capital Raise. (Incorporated by reference to Registrant’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2011, filed with the Securities and Exchange Commission on November 21, 2011.) |
|    |                                                                                                                                                                                                                                                                                                                                                 |
| 10.11   | Promissory Note dated September 2, 2011 issued by Registrant to Clubb Capital Limited for the deferred portion of the placement agent commission. (Incorporated by reference to Registrant’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2011, filed with the Securities and Exchange Commission on November 21, 2011.)  |

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| 10.12    | Form of Promissory Notes issued by Registrant in favor of investors since 2012 aggregating $4,130,000 in principal amount through April 30, 2014, including schedule of investors.(3)                                                                                                                                                                                                                                                                                                                                                                                                                                 |
|----------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |
| 10.13    | Employment Agreement dated September 8, 2006, between the Registrant and John Benson. (Incorporated by reference to the Registrant’s report on Form 10-K for the year ended December 31, 2011 filed with the Securities and Exchange Commission on March 30, 2012.) (2)                                                                                                                                                                                                                                                                                                                                         |
|     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |
| 10.13(a) | Compensation arrangement with John Benson. (Incorporated by reference to the Registrant’s report on Form 10-K for the year ended December 31, 2011 filed with the Securities and Exchange Commission on March 30, 2012.) (2)                                                                                                                                                                                                                                                                                                                                                                                    |
|     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |
| 21       | List of subsidiaries. (Incorporated by reference to the Registrant’s report on Form 10-K for the year ended December 31, 2011 filed with the Securities and Exchange Commission on March 30, 2012.)                                                                                                                                                                                                                                                                                                                                                                                                             |
|     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |
| 23.1     | Consent of EisnerAmper LLP. (1)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       |
|     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |
| 31.1     | Certification of Principal Executive Officer Pursuant to Exchange Act Rule 13a-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. (3)                                                                                                                                                                                                                                                                                                                                                                                                                                                       |
|     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |
| 31.2     | Certification of Principal Financial Officer Pursuant to Exchange Act Rule 13a-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. (3)                                                                                                                                                                                                                                                                                                                                                                                                                                                       |
|     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |
| 101      | Interactive data files pursuant to Rule 405 of Regulation S-T: (i) the Condensed Statements of Operations for the years ended December 31, 2013 and 2012 and the cumulative period from November 4, 2008 (inception) to December 31, 2013, (ii) the Condensed Consolidated Balance Sheets at December 31, 2013 and December 31, 2012, (iii) the Condensed Consolidated Statements of Cash Flows for the years ended December 31, 2013 and 2012 and the cumulative period from November 4, 2008 (inception) to December 31, 2013 and (iv) the Notes to the Condensed Consolidated Financial Statements.  (1) |

| (1) | Previously filed with the original filing of this Annual Report on Form 10-K on March 31, 2014. |
|-----|-------------------------------------------------------------------------------------------------|
| (2) | Indicates a management contract or compensatory plan or arrangement.                            |
| (3) | Filed herewith.                                                                                 |

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|                  | Pathfinder Cell Therapy, Inc. |                          |
|-----------------------|-------------------------------|-------------------------------|
|                  | (Registrant)                  |                          |
|                  |                          |                          |   |
|                  | By:                           | /s/ Richard L. Franklin, M.D. |   |
|                  |                          | Richard L. Franklin, M.D.     |   |
|                  |                          | CEO and President             |   |
| Dated: April 30, 2014 |                          |                          |   |

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