EXHIBIT 10.54
*Certain information omitted and filed separately with the Securities and
Exchange Commission pursuant to Rule 24b-2(b).
------------------------------------------------------------------------

Agreement, dated as of April 1, 1997, between Interferon Sciences, Inc., a
Delaware corporation with principal executive offices at 783 Jersey Avenue, New
Brunswick, New Jersey 08901 ("ISI"), and American National Red Cross, a
charitable and not-for-profit corporation with principal offices at 8111
Gatehouse Road, Falls Church, Virginia 22042 ("ARC").

WHEREAS, ARC's mission is to provide a safe, reliable, and cost effective supply
of blood and blood services;

WHEREAS, ARC is the pre-eminent provider of blood and blood services in the
United States, serving more than 3,000 hospitals through the generous donations
of some 22,000 people daily;

WHEREAS, ARC, as a by-product of its blood collection activities, collects
buffycoats;       WHEREAS, ISI is a biopharmarceutical company currently engaged
in the manufacture and sale of natural source, multi-species alpha interferon
("Natural Alpha Interferon"); and

WHEREAS, ISI wishes to purchase from ARC, and ARC wishes to sell to ISI,
buffycoats to be used by ISI in the manufacture of Natural Alpha Interferon; 
NOW, THEREFORE, in consideration of the premises and the mutual covenants and
agreements contained herein, ISI and ARC agree as follows (capitalized terms 
used and not defined herein have the meanings as defined in Section 8):

1.    Purchase and Sale of Buffycoats

      1.1   Purchase and Sale.  Subject to the terms and conditions set forth
herein, ISI agrees to purchase from ARC, and ARC agrees to sell to ISI,
buffycoats for use in the manufacture of Natural Alpha Interferon.

      1.2   Orders. (a) In each of the first seven months of the Term, ISI shall
purchase from ARC, and ARC shall sell to ISI, the number of buffycoats set forth
for such month on Schedule 1.2. 

      (b)    In each of the eighth through twenty-fourth months of the Term, ISI
shall purchase from ARC, and ARC shall sell to ISI, at least the number of
buffycoats set forth for such month on Schedule l.2 under the heading "Minimum
Purchases."  Not later than the first day of each of the second through
eighteenth months of the Term, ISI shall submit to ARC a purchase order for
buffycoats for the sixth succeeding month. If the purchase order relating to any
month is for a number of buffycoats (i) less than or equal to the number of
buffycoats set forth for such month on Schedule l.2 under the heading "Minimum
Sales," such purchase order shall be binding on both parties, and ISI shall
purchase from ARC, and ARC shall sell to ISI, the number of buffycoats set forth
in such order or (ii) greater than the number of buffycoats set forth for such
month on Schedule l.2 under the heading "Minimum Sales," (A) such purchase order
shall be binding on both parties with respect to the number of buffycoats set
forth for such month on Schedule l.2 under the heading "Minimum Sales," and ISI
shall purchase from ARC, and ARC shall sell to ISI, such number of buffycoats,
(B) ARC shall notify ISI, not more than 10 days after its receipt of such
purchase order, of the number of buffycoats, if any, ARC is willing to supply in
such month in excess of the number of buffycoats set forth for such month on
Schedule l.2 under the heading "Minimum Sales," and (C) ARC shall use its
commercially reasonable efforts to sell to ISI the number of buffycoats set
forth in such notice from ARC.

      1.3   Purchase Price and Payment.  (a)  The purchase price to ISI for all
buffycoats it purchases hereunder shall be determined pursuant to Schedule 1.3. 

      (b)   As soon as practicable after the end of each of the first eleven
months of each Year, ARC shall invoice ISI for buffycoats purchased in such
month and the related shipping expenses, with the price per buffycoat determined
by assuming that the Buffycoat Number for such Year will equal the Buffycoat
Number for such month multiplied by 12.  As soon as practicable after the end of
the twelfth month of each Year, ARC shall send ISI a final invoice for such Year
(the "Final Invoice") in an amount equal to (i) the number of buffycoats
purchased in such Year multiplied by the price per buffycoat less (ii) the
aggregate amount of the previous eleven invoices for such Year (excluding
shipping expenses) plus (iii) the shipping expenses incurred in such month.

      (c)   For invoices relating to the first Year, ISI shall pay (i) * % of
each invoiced amount in cash within 30 days from the date of such invoice and
(ii) the remaining * % of each invoiced amount (the "Unpaid Amount") as set
forth in Sections 1.3(m) and (n).  

      (d)  If ISI gives ARC, or ARC gives ISI, not later than April 1, 1998
(the "First Anniversary Date"), a notice (the "Equity Election") that it elects
to have this sentence apply to invoices relating to the second Year, then for
invoices relating to the second Year, ISI shall pay (i) * % of each invoiced
amount in cash within 30 days from the date of such invoice and (ii) the Unpaid
Amount as set forth in Sections 1.3(m) and (n).  If the Equity Election is not
made, for invoices relating to the second Year, ISI shall pay 100% of each
invoiced amount in cash within 30 days from the date of such invoice. 

      (e)   If the Market Price on the First Anniversary Date (the "First
Anniversary Price") exceeds the Market Price on the date this Agreement is
executed (the "Opening Price"), ISI will issue to ARC, as soon as practicable
after the First Anniversary Date, a number of shares  (the "First Shares") of
common stock, par value $.01 per share (the "Common Stock"), of ISI calculated
as follows: [(First Anniversary Price - Opening Price) x Formula Share Number]
, First Anniversary Price.  An illustration of the operation of this Section
1.3(e) and Sections 1.3(f), (m), and (n) is set forth on Schedule 1.3(e).

      (f)   If the Equity Election is made and the Market Price (the "Second
Anniversary Price") on April 1, 1999 (the "Second Anniversary Date") exceeds the
First Anniversary Price, ISI will issue to ARC, as soon as practicable after the
Second Anniversary Date, a number of shares (the "Second Shares") of Common
Stock calculated as follows: [(Second Anniversary Price - First Anniversary
Price) x Formula Share Number] , Second Anniversary Price.

      (g)   The calculations set forth in Sections 1.3(e) and (f) shall be
subject to the following adjustments:

            (i)   In case at any time after the date hereof and prior to the
First Anniversary Date (or prior to the Second Anniversary Date if the Equity
Election is made) ISI shall subdivide its outstanding shares of Common Stock
into a greater number of shares or declare a dividend on its outstanding shares
of Common Stock payable in shares of Common Stock, the Formula Share Number in
effect immediately prior thereto shall be proportionately increased, and, if the
subdivision or dividend shall occur in the first Year, the Opening Price used in
the determination pursuant to Section 1.3(e), or, if the subdivision or dividend
shall occur in the second Year, the First Anniversary Price used in the
determination pursuant to Section 1.3(f), in effect immediately prior thereto
shall be proportionately reduced.  Conversely, in case the outstanding shares of
Common Stock shall be combined into a smaller number of shares, the Formula
Share Number in effect immediately prior to such combination shall be
proportionately reduced, and, if the combination shall occur in the first Year,
the Opening Price used in the determination pursuant to Section 1.3(e), or, if
the combination shall occur in the second Year, the First Anniversary Price used
in the determination pursuant to Section 1.3(f), as in effect immediately prior 
to such combination shall be proportionately increased.

            (ii)  In case at any time after the date hereof and prior to the
First Anniversary Date (or prior to the Second Anniversary Date if the Equity
Election is made), ISI shall be a party to any transaction (including, without
limitation, a merger, consolidation, sale of all or substantially all of its
assets, or recapitalization of its capital stock) (each such transaction being
herein called a "Transaction" and the consummation date of each such transaction
being herein called a "Consummation Date") in which the previously outstanding
shares of Common Stock shall be changed into or exchanged for different
securities of ISI or common stock or other securities of another corporation or
interests in a oncorporate entity or other property (including cash) or any
combination of any of the foregoing (the "Transaction Consideration"), then as
a condition to the consummation of the Transaction, lawful and adequate
provision shall be made so that ARC shall be entitled to receive, (A) if the
Consummation Date is prior to the First Anniversary Date, in lieu of First
Shares, Transaction Consideration having a fair market value on the First 
Anniversary Date equal to the amount, if any, by which (I) the fair market value
on the First Anniversary Date of the Transaction Consideration a holder 
immediately prior to the Consummation Date of the Formula Share Number of Common
Stock would have been entitled to receive upon the consummation of the 
Transaction exceeds (II) the product of the Opening Price and the Formula Share 
Number and (B) if the Consummation Date is after the First Anniversary Date but 
prior to the Second Anniversary Date and the Equity Election is made, in lieu of
Second Shares, Transaction Consideration having a fair market value on the 
Second Anniversary Date equal to the amount, if any, by which (I) the fair 
market value on the Second Anniversary Date of the Transaction Consideration a 
holder immediately prior to the Consummation Date of the Formula Share Number of
Common Stock would have been entitled to receive upon the consummation of the 
Transaction exceeds (II) the product of the First Anniversary Price and the 
Formula Share Number.  As a further condition to the consummation of the 
Transaction, lawful and adequate provision shall be made so that all of ISI's 
obligations to pay ARC the Unpaid Amount or any part thereof pursuant to 
Sections 1.3(m) and (n) shall become the obligations of ISI and of its
successor in interest, provided, however, that any amount received pursuant to 
this Section 1.3(g)(ii) in cash shall be deemed to reduce, to that extent, the 
amount of any deficiency of the Unpaid Amount which ISI and its successor in 
interest shall be obligated to pay ARC pursuant to Sections 1.3(m) and (n).

      (h)   The issue and sale of the First Shares and Second Shares
(collectively, the "Shares") to ARC pursuant to Sections l.3(e) and (f) will not
be registered under the Securities Act of 1933, as amended (the "Act"), in
reliance upon the applicability of Section 4(2) of the Act to the transactions
contemplated thereby.  In furtherance of such reliance, certificates 
representing the Shares will bear a restrictive legend to the effect that they 
may not be sold without registration under the Act, absent an available 
exemption from the registration provisions of the Act, and appropriate "stop 
transfer" instructions will be issued to the transfer agent for Common Stock.  
ARC acknowledges that it has had access to such knowledge about ISI as is 
customarily found in a registration statement filed under the Act and agrees 
that it will acquire the Shares for investment and not with a view to 
distribution and will not sell or otherwise dispose of the Shares except in 
compliance with the Act, including pursuant to an exemption from registration 
under the Act which, in the opinion of counsel to ARC, which counsel and
opinion are reasonably satisfactory to counsel of ISI, is available for a 
proposed disposition of any of the Shares.

 .     (i)  ISI shall, at its expense (except as provided in Appendix A), (i) not
later than 90 days prior to the First Anniversary Date, file a registration
statement (the "First Registration Statement") to register under the Act the
resale by ARC of the First Shares, (ii) take all commercially reasonable actions
to cause the First Registration Statement to become effective under the Act  as
expeditiously as possible after the First Anniversary Date, (iii) after the 
First Registration Statement is declared effective under the Act, furnish ARC 
with such number of copies of the prospectus (the "First Prospectus") included 
in the First Registration Statement as ARC may reasonably request to facilitate
the resale of the First Shares, (iv) take all commercially reasonable actions to
register and qualify the First Shares under such securities laws (other than the
Act) or Blue Sky laws of such jurisdictions as shall be reasonably requested by 
ARC, provided that ISI shall  not be required in connection therewith or as a 
condition thereto to qualify to do business or to file a general consent to 
service of process in any such states or jurisdictions, and (v) take all 
commercially reasonable actions to (A) cause the First Registration Statement to
remain effective under the Act and such state registrations or qualifications to
remain effective under such state securities or Blue Sky laws, (B) prepare and 
file under the Act such amendments and supplements to the First Registration 
Statement and the First Prospectus as may be necessary to comply with the 
provisions of the Act and the rules thereunder with respect to the disposition 
of all securities covered by the First Registration Statement, and (C) file such
supplements and amendments to any such state registrations or qualifications as 
may be necessary to comply with the provisions of such state securities or
Blue Sky laws with respect to the disposition of all securities covered by such 
registration or qualification.  The obligations of ISI in the preceding sentence
shall terminate at the earlier of (A) such time as ARC owns no First Shares and
(B) such time as, in the view of counsel to ISI concurred in by counsel to ARC, 
ARC may sell all of the First Shares then held by ARC in the public securities 
market without registration under the Act pursuant to Rule 144 under the Act (or
any successor rule).  It shall be a condition precedent to the obligations of
ISI under this Section 1.3(i) that ARC shall furnish to ISI such information as
requested in writing by ISI regarding ARC, the First Shares held by ARC, and the
intended method of disposition of such First Shares as shall be required to 
effect the registration of the First Shares. 

      (j)   If the Equity Election is made, ISI shall, at its expense (except as
provided in Appendix A), (i) not later than 90 days prior to the Second
Anniversary Date, file a registration statement (the "Second Registration
Statement," and, together with the First Registration Statement, the
"Registration Statements") to register under the Act the resale by ARC of the
Second Shares, (ii) take all commercially reasonable actions to cause the Second
Registration Statement to become effective under the Act as expeditiously as
possible after the Second Anniversary Date, (iii) after the Second Registration
Statement is declared effective under the Act, furnish ARC with such number of
copies of the prospectus (the "Second Prospectus") included in the Second
Registration Statement as ARC may reasonably request to facilitate the resale of
the Second Shares, (iv) take all commercially reasonable actions to register and
qualify the Second Shares under such securities laws (other than the Act) or
Blue Sky laws of such jurisdictions as shall be reasonably requested by ARC, 
provided that ISI shall  not be required in connection therewith or as a
condition thereto to qualify to do business or to file a general consent to 
service of process in any such states or jurisdictions, and (v) take all 
commercially reasonable actions to (A) cause the Second Registration Statement
to remain effective under the Act and such state registrations or qualifications
to remain effective under such state securities or Blue Sky laws, (B) prepare 
and file under the Act such amendments and supplements to the Second 
Registration Statement and the Second Prospectus as may be necessary to comply 
with the provisions of the Act and the rules thereunder with respect to the 
disposition of all securities covered by the Second Registration Statement, and
(C) file such supplements and amendments to any such state registrations or 
qualifications as may be  necessary to comply with the provisions of such state 
securities or Blue Sky laws with respect to the disposition of all securities 
covered by such registration or qualification.  The obligations of ISI in the 
preceding sentence shall terminate at the earlier of (A) such time as ARC owns 
no Second Shares and (B) such time as, in the view of counsel to ISI concurred 
in by counsel to ARC, ARC may sell all of the Second Shares then held by ARC in 
the public securities market without registration under the Act pursuant to Rule
144 under the Act (or any successor rule).  It shall be a condition precedent to
the obligations of ISI under this Section 1.3(j) that ARC shall furnish to ISI 
such information as requested in writing by ISI regarding ARC, the Second Shares
held by ARC, and the intended method of disposition of such Second Shares as 
shall be required to effect the registration of the Second Shares. 

      (k)   If at any time during the period that ARC owns any Shares an event
(an "Event") shall have occurred that has caused the First Prospectus or the
Second Prospectus to contain an untrue statement of a material fact or to omit
to state any material fact required to be stated therein or necessary to make 
the statements therein not misleading in light of the circumstances under which
they were made, ISI shall promptly (i) give ARC a notice (the "No-Sell Notice")
that an Event has occurred, (ii) promptly (or, if in the reasonable judgment of
ISI disclosure of the Event would be seriously detrimental to ISI, promptly 
after disclosure of the Event would not be seriously detrimental to ISI) take 
all commercially reasonable efforts to cause the First Registration Statement 
and the Second Registration Statement not to contain an untrue statement of a 
material fact or to omit to state any material fact required to be stated 
therein or necessary to make the statements therein not misleading in light of 
the circumstances under which they were made, and (iii) give ARC a notice (the 
"Sell Notice") when the First Registration Statement and the Second 
Registration Statement do not contain an untrue statement of a material fact or
to omit to state any material fact required to be stated therein or necessary to
make the statements therein not misleading in light of the circumstances under 
which they were made.  ARC shall not sell any Shares pursuant to the First 
Registration Statement or Second Registration Statement after it has received a 
No-Sell Notice until it has received a subsequent Sell Notice.

      (l)   In addition to the provisions of this Agreement, the provisions of
Appendix A are incorporated herein by this reference as fully as if set forth
herein and those provisions shall apply with respect to the First Registration
Statement and the Second Registration Statement and shall otherwise govern the
rights of the parties with respect to the First Shares and the Second Shares. 
In the event of a Transaction, the foregoing registration rights and the
provisions of Appendix A shall apply to any Transaction Consideration received
by ARC in lieu of Shares unless, in the opinion of counsel to ISI or its
successor, registration is not required for the resale of such Transaction
Consideration by ARC, which opinion is concurred in by counsel to ARC.

      (m)   If any First Shares or Transaction Consideration are issued, not
later than ten business days after the later of (A) the First Anniversary Date
and (B) the date that ARC receives a copy of ISI's Annual Report on Form 10-K 
for the fiscal year ended December 31, 1997, ARC shall give ISI notice whether
it elects to sell the First Shares or Transaction Consideration pursuant to the
provisions of this Section 1.3(m).  If ARC elects not to sell the First Shares
or Transaction Consideration pursuant to the provisions of this Section 1.3(m),
the First Shares or Transaction Consideration shall constitute full payment for
the first Year's Unpaid Amount.  If ARC elects to sell the First Shares or
Transaction Consideration pursuant to the provisions of this Section 1.3(m), it
will cooperate with any reasonable request of ISI in order to maximize the Sales
Proceeds.  If the Sales Proceeds are less than the first Year's Unpaid Amount,
ISI shall promptly pay the deficiency to ARC in cash.  If ARC elects to sell the
First Shares or Transaction Consideration pursuant to the provisions of this
Section 1.3(m) but cannot do so because the First Registration Statement has not
been declared effective under the Act or ARC has received a No-Sell Notice but
has not received a subsequent Sell Notice, ISI shall promptly pay the first
Year's Unpaid Amount to ARC in cash.  At such time as ARC is able to sell the
First Shares or Transaction Consideration, ARC shall promptly pay to ISI in cash
the lesser of (i) the first Year's Unpaid Amount and (ii) the Sales Proceeds. 
If no First Shares or Transaction Consideration are issued, ISI shall pay the
first Year's Unpaid Amount to ARC in cash within 30 days from the date of the
Final Invoice for the first Year.  ISI's obligation to pay the first Year's
Unpaid Amount shall remain in full force and effect until fully satisfied by
either (iii) the delivery of a written notice by ARC that it elects not to sell
the First Shares or Transaction Consideration pursuant to the provisions of this
Section 1.3(m), (iv) the application of the Sales Proceeds of the First Shares
or Transaction Consideration to the first Year's Unpaid Amount and receipt from
ISI of payment for any deficiency, or (v) the payment of the first Year's Unpaid
Amount in cash, in each case as provided for pursuant to this Section 1.3(m).

      (n)   If the Equity Election is made and any Second Shares or Transaction
Consideration are issued, not later than ten business days after the later of 
(A) the Second Anniversary Date and (B) the date that ARC receives a copy of 
ISI's Annual Report on Form 10-K for the fiscal year ended December 31, 1998, 
ARC shall give ISI notice whether it elects to sell the Second Shares or 
Transaction Consideration pursuant to the provisions of this Section 1.3(n).  If
ARC elects not to sell the Second Shares or Transaction Consideration pursuant 
to the provisions of this Section 1.3(n), the Second Shares or Transaction 
Consideration shall constitute full payment for the second Year's Unpaid Amount.
If ARC elects to sell the Second Shares or Transaction Consideration pursuant to
the provisions of this Section 1.3(n), it will cooperate with any reasonable 
request of ISI in order to maximize the Sales Proceeds.  If the Sales Proceeds 
are less than the second Year's Unpaid Amount, ISI shall promptly pay the 
deficiency to ARC in cash.  If ARC elects to sell the Second Shares or 
Transaction Consideration pursuant to the provisions of this Section 1.3(n) but
cannot do so because the Second Registration Statement has not been declared 
effective under the Act or ARC has received a No-Sell Notice but has not 
received a subsequent Sell Notice, ISI shall promptly pay the second Year's 
Unpaid Amount to ARC in cash.  At such time as ARC is able to sell the Second 
Shares or Transaction Consideration, ARC shall promptly pay to ISI in cash the 
lesser of (i) the second Year's Unpaid Amount and (ii) the Sales Proceeds.  If 
no Second Shares or Transaction Consideration are issued, ISI shall pay the 
second Year's Unpaid Amount to ARC in cash within 30 days from the date of the 
Final Invoice for the second Year. ISI's obligation to pay the second Year's 
Unpaid Amount shall remain in full force and effect until fully satisfied by 
either (iii) the delivery of a written notice by ARC that it elects not to sell
the Second Shares or Transaction Consideration pursuant to the provisions of 
this Section 1.3(n), (iv) the application of the Sales Proceeds of the Second 
Shares or Transaction Consideration to the second Year's Unpaid Amount and 
receipt from ISI of payment for any deficiency, or (v) the payment of the second
Year's Unpaid Amount in cash, in each case as provided for pursuant to this 
Section 1.3(n). 

2.    Delivery of Buffycoats

      2.1   Shipment and Acceptance of Buffycoats.  Buffycoats shall be shipped
at ISI's expense from each ARC Blood Services Region (a "Region") to ISI's New
Brunswick, New Jersey facility (the "ISI Facility") in such manner as ISI and
ARC shall agree.  Title to  buffycoats shall be transferred to and vest in ISI 
at the time ISI accepts the buffycoats.  ISI shall not be required to accept 
buffycoats shipped by ARC unless, not later than 3 P.M. on the day following the
day such buffycoats are drawn from the blood donor, (a) such buffycoats shall 
have been received at the ISI Facility and (b) ARC shall have furnished to ISI a
written notice certifying (i) the day such buffycoats were drawn from the blood
donor, (ii) that ARC tested such buffycoats in accordance with the testing
procedures set forth on Schedule 2.1, and (iii) that such buffycoats did not 
fail any such test procedures.  Any buffycoats not accepted by ISI shall be 
destroyed by ISI in accordance with all applicable laws and ARC requirements and
Standard Operating Procedures or, if so requested by ARC, returned to ARC at 
ARC's expense.

      2.2   Shipment by Regions.  Except as set forth in this Section 2.2, ARC
shall determine which Regions will ship buffycoats to ISI.  If any Region shall
produce buffycoats using a process different from that used by the majority of
Regions on the date of this Agreement (a "Different Process Region"), ARC shall
not ship such buffycoats to ISI unless ISI shall have first determined that such
buffycoats are suitable for use in the manufacture of Natural Alpha Interferon. 
If ARC wants to ship buffycoats produced at a Different Process Region, ARC
shall, at its expense, furnish such buffycoats to ISI to enable ISI to determine
whether such buffycoats are suitable for use in the manufacture of Natural Alpha
Interferon.  If ISI shall determine that such buffycoats are suitable for use in
the manufacture of Natural Alpha Interferon, ISI shall so notify ARC and ARC
shall be permitted to ship to ISI buffycoats produced by such Different Process
Region.  If ISI shall determine that such buffycoats are not suitable for use in
the manufacture of Natural Alpha Interferon, ISI shall so notify ARC and ARC
shall not ship to ISI buffycoats produced by such Different Process Region.


      2.3   Timing of Shipments of Buffycoats.  ISI and ARC shall cooperate to
insure that the buffycoats to be purchased by ISI and sold by ARC are shipped in
an orderly manner so as to allow ISI to utilize them efficiently in the
manufacture of Natural Alpha Interferon.  Without limiting the generality of the
foregoing, (a) ARC shall not ship more than   *   buffycoats to be received by
ISI on any day, unless given written permission by ISI, and (b) if ISI gives ARC
written notice (a "No Ship Notice") that the ISI Facility will not be operating
on any day or days, ARC shall not ship any buffycoats to be received by ISI on
such day or days provided that the No Ship Notice is faxed by ISI to each Region
then shipping buffycoats to ISI not later than noon of the day preceding the day
such buffycoats are collected.  ARC shall furnish to ISI from time to time the
fax numbers of the Regions then shipping buffycoats to ISI.  If, as a result of
a No Ship Notice or No Ship Notices, the number of days in any month of the Term
on which ISI is able to receive buffycoats (the "Open Days Number") is less than
the number of days set forth for such month on Schedule 1.2 under the heading
"Minimum Days" (the "Minimum Days Number"),(c) with respect to the first through
seventh months of the Term, the number of buffycoats set forth for such month on
Schedule 1.2 under the heading "Quantity" shall be reduced by the product of (i)
the quotient obtained by dividing (A) the number of buffycoats set forth for 
such month on Schedule 1.2 under the heading "Quantity" by (B) the Minimum Days
Number for such month and (ii) the number by which the Minimum Days Number for 
such month exceeds the Open Days Number for such month, and (d) with respect to
the eighth through twenty-fourth months of the Term, the number of buffycoats
set forth for such month on Schedule 1.2 under the heading "Minimum Sales" shall
be reduced by the product of (i)   *    and (ii) the number by which the Minimum
Days Number for such month exceeds the Open Days Number for such month, and in
case of both clauses (c) and (d) ARC shall not be obligated to sell to ISI in
such month a number of buffycoats in excess of such reduced number of
buffycoats.

3.    Confidential Information

      3.1   Use.  All Confidential Information of a party hereto shall be used
by the other party only during the Term and solely for the purpose of performing
its obligations hereunder.

      3.2   Confidential Treatment.  Each party agrees that it will keep
confidential the other party's Confidential Information and shall not, without
the prior written consent of the other party, disclose or permit the disclosure
by it or by its representatives or employees of such Confidential Information,
in any manner whatsoever, in whole or in part, except as specifically
contemplated by this Agreement, and that such party will only reveal the other
party's Confidential Information to such representatives and employees of the
receiving party who need to know the Confidential Information for the purpose of
performing the obligations of the receiving party hereunder and that such
representatives and employees will be informed by the receiving party of and
agree with the receiving party to maintain the confidential nature of the
Confidential Information.

      3.3   Required Disclosure.  Each party agrees that, if such party becomes
legally compelled to disclose any of the other party's Confidential Information,
it will provide such other party with prompt notice so that such other party may
seek a protective order or other appropriate remedy.  If such protective order
or other remedy is not timely obtained, or such other party waives compliance
with the provisions of this Section 3, the party compelled to make such
disclosure shall only furnish that portion of the Confidential Information 
which, on the advice of counsel, it reasonably determines it is legally required
to furnish and will use its commercially reasonable efforts to obtain reliable
assurance that confidential treatment will be accorded such Confidential
Information.

      3.4   Return on Termination.  Upon termination of this Agreement, each
party shall use its commercially reasonable efforts to return to the other party
all Confidential Information acquired by it from such other party and all copies
thereof.

      3.5   Injunctive Relief.  Each party hereto acknowledges and agrees that
any breach by such party of the provisions of this Section 3 could cause
irreparable harm to the other party, and that the resulting damages and injuries
to such other party might be incalculable and irremediable.  Accordingly, the
parties agree that, in the event of such breach, the other party shall be
entitled to injunctive relief and specific performance of the covenants 
contained herein, in addition to any other remedy to which it may be entitled in
law or equity.

4.    Force Majeure

      Neither party shall be liable for any loss, damage, delay, or failure to
perform hereunder resulting from causes beyond its control, including, but not
limited to, fire, flood, earthquake, war, embargo, strikes, lockouts, labor
troubles, accident, explosion, riot, insurrection, governmental laws or
regulations (other than such laws and regulations relating to the sale of
securities), taking of its property by governmental authority, quarantine by
governmental authority, breakdown of equipment, or shortages of materials or
labor or supplies of any kind (other than shortages resulting from a party's
failure to order or take reasonable steps to procure such materials, labor, or
supplies).  If either party shall become aware of any event described in this
Section 4 which could reasonably be expected to affect such party's performance
of its obligations hereunder, it shall promptly give notice thereof to the other
party.

5.    Representations and Covenants

      5.1   Representations By ARC.  ARC represents and warrants as follows:

            (a)   ARC is a charitable and not-for-profit corporation chartered
by Congress, with all requisite corporate power and authority to carry on the
business in which it is engaged and to enter into and perform its obligations
under this Agreement.

            (b)  All necessary corporate proceedings of ARC have been duly taken
to authorize the execution, delivery, and performance of this Agreement by ARC. 
This Agreement has been duly authorized, executed, and delivered by ARC,
constitutes the legal, valid, and binding obligation of ARC, and is enforceable
as to it in accordance with its terms.

            (c)   No consent, authorization, approval, order, license,
certificate, or permit of or from, or declaration or filing with, any federal,
state, local, or other governmental authority is required by ARC for its
execution, delivery, and performance of this Agreement.  No consent of any party
to any contract, agreement, instrument, lease, license, arrangement, or
understanding to which ARC is a party, or to which it or any of its businesses,
properties, or assets are subject, is required for the execution, delivery, or
performance of this Agreement; and the execution, delivery, and performance of
this Agreement will not violate, result in a breach of, or conflict with any
such contract, agreement, instrument, lease, license, arrangement, or 
understanding, or violate, result in a breach of, or conflict with any law, 
rule, regulation, order, judgment, or decree binding on ARC or to which it or
any of its businesses, properties, or assets are subject or any authorizing 
statute or corporate bylaws of ARC.

      5.2   Representations and Covenants By ISI. 

            The following representations and warranties shall be deemed to be
given to ARC on the date first above written, on the date an Equity Election is
made pursuant to Section 1(d), on the date of a notice by ARC of its election to
sell or not to sell the First Shares pursuant to Section 1.3(m), and on the date
of a notice by ARC of its election to sell or not to sell the Second Shares
pursuant to Section 1.3(n).

            (a)   ISI is a corporation duly organized, validly existing, and in
good standing under the laws of Delaware, with all requisite corporate power and
authority to carry on the business in which it is engaged and to enter into and
perform its obligations under this Agreement.  ISI is duly qualified and in good
standing as a foreign corporation in each jurisdiction in which failure to so
qualify would have a material adverse effect on its business, properties, or
assets.

            (b)  All necessary corporate proceedings of ISI have been duly taken
to authorize the execution, delivery, and performance of this Agreement by ISI. 
This Agreement has been duly authorized, executed, and delivered by ISI,
constitutes the legal, valid, and binding obligation of ISI, and is enforceable
as to it in accordance with its terms.  The Shares are and when issued shall be
duly authorized and, when issued pursuant to the terms of this Agreement, shall
be duly and validly issued, fully paid and nonassessable, without any personal
liability attaching to the ownership thereof, and the issuance of such Shares
will not violate any preemptive rights of stockholders.  ARC will receive good
title to the Shares, when issued, free and clear of all liens, charges, security
interests, encumbrances, and voting trusts of every kind and nature whatsoever,
other than those arising from the actions or failure to act of ARC.  No
stockholder approval is required for ISI to issue and deliver the Shares to be
issued pursuant to this Agreement.

            (c)   No consent, authorization, approval, order, license,
certificate, or permit of or from, or declaration or filing with, any federal,
state, local, or other governmental authority is required by ISI for its
execution, delivery, and performance of this Agreement.  No consent of any party
to any contract, agreement, instrument, lease, license, arrangement, or
understanding to which ISI is a party, or to which it or any of its businesses,
properties, or assets are subject, is required for the execution, delivery, or
performance of this Agreement; and the execution, delivery, and performance of
this Agreement will not violate, result in a breach of, or conflict with any 
such contract, agreement, instrument, lease, license, arrangement, or 
understanding, or violate, result in a breach of, or conflict with any law, 
rule, regulation, order, judgment, or decree binding on ISI or to which it or 
any of its businesses, properties, or assets are subject or any provision of 
ISI's certificate of incorporation or bylaws.

            (d)   As of the date hereof, the authorized capital of ISI consists
of (i) 55,000,000 shares of Common Stock, of which approximately 12,285,105
shares are issued and outstanding, and (ii) 5,000,000 shares of preferred stock,
none of which are issued and outstanding.  All outstanding shares of capital
stock are duly and validly issued, fully paid, and nonassessable.

            (e)   ISI has delivered to ARC a true and correct copy of ISI's
Annual Report on Form 10-K for the fiscal year ended December 31, 1996 as filed
with the Securities and Exchange Commission (the "Commission"").  ISI shall
deliver to ARC, promptly as filed, a true and correct copy of each report filed
by ISI with the Commission on Form 10-K, 10-Q,  or 8-K (collectively, "SEC
Reports"), and shall deliver to ARC promptly as mailed a copy of all
communications distributed to the holders of its Common Stock (collectively,
"Stockholder Communications").  The foregoing obligations shall remain in effect
so long as any Shares remain to be issued pursuant to this Agreement.  ISI
represents and warrants that no SEC Report or Stockholder Communication 
delivered by ISI to ARC pursuant to this Section 5.2(e) has contained or will 
contain any untrue statement of a material fact or has omitted or will omit to 
state a material fact required to be stated therein or necessary to make the 
statements therein, in light of the circumstances under which they were made, 
not misleading, provided, however, that ISI shall have no liability for any 
breach of the representation and warranty set forth in this sentence unless ISI
commits a breach thereof by making with scienter any such untrue statement of a
material fact or omitting with scienter to state a material fact required to be
stated therein or necessary to make the statements therein, in light of the
circumstances under which they were made, not misleading.

            (f)   After the date hereof and prior to the First Anniversary Date
(or prior to the Second Anniversary Date if the Equity Election is made), ISI
shall not declare a dividend on its outstanding shares of Common Stock payable
(i) in part in shares of Common Stock (the foregoing shall not apply to a
dividend on its outstanding shares of Common Stock payable in whole in shares of
Common Stock) or (ii) in other securities exchangeable or convertible into
Common Stock.      

            (g)   ISI shall, at its sole expense, keep in force the following
policies of insurance (the "Policies") in the amounts specified:

                  (i)   a Commercial General Liability Policy with the following
conditions to benefit ARC:  (A) ARC and its officers, agents, employees, and
volunteers are named as additional insureds and (B) the amount of the Policy 
will be at least $5,000,000 combined single limit for each occurrence;

                  (ii)  a Products Liability Policy specifically insuring claims
for bodily injury, death, or property damage arising from development of 
products or professional services (Errors & Omissions) and applicable to the 
manufacture of any product of ISI, including, but not limited to, coverage for 
Natural Alpha Interferon, with the following conditions to benefit ARC:  (A) ARC
and its officers, agents, employees, and volunteers are named as additional 
insureds and (B) the amount of the Policy will be at least $10,000,000 combined
single limit for each occurrence;

                  (iii) Workers' Compensation coverage with statutory limits for
each jurisdiction where the work required under this Agreement is performed;

                  (iv)  an employers' liability Policy with at least the
following limits: $1,000,000 per accident, $1,000,000 per disease, and 
$1,000,000 disease (each employee); and

                  (v)   such other Policies as may be required by statute.
All such Policies shall be maintained with companies, in forms, and with
deductibles reasonably acceptable to ARC and will be written as primary policy
coverage and not contributing with, or in excess of, any coverage which the ARC
may carry; the Policies will respond to claims brought in domestic or foreign
courts of law; the insurance shall be obtained under valid and enforceable
Policies issued by insurers licensed in the states in which this Agreement is
being carried out; all companies writing the Policies shall be A.M. Best rated
A 10 or higher; certificates of insurance evidencing all of the above coverages
and conditions (types and amounts) shall be and remain in full force and effect
during the term of this Agreement; ISI shall provide ARC with all required
certificates of insurance prior to the commencement of services and renewal
certificates within ten days of expiration or non-renewal of the Policies
required herein, as long as this Agreement is in effect; in the "Cancellation
Clause" the certificate shall read "in the event of nonrenewal of policies,
cancellation, or material change in the coverage provided, not less than thirty
(30) days prior written notice will be furnished to ARC prior to the date of
nonrenewal, cancellation, or change;" and the liabilities assumed in this
Agreement will be insured by such Policies and the full limits of such Policies
will be  available to protect ISI and ARC from such liabilities (subject to
impairment of annual aggregate Policy limits by claims filed prior to ARC's
claims).  ARC acknowledges and agrees that the Policies listed on Appendix B
satisfy ISI's obligations under this Section 5.2(g) to the extent information
about such Policies is set forth on Appendix B. 

      (h)   ISI will comply with all applicable laws, rules, regulations, and
recommendations of the United States Food and Drug Administration, Environmental
Protection Agency, Occupational Safety and Health Administration, and any other
federal, state, or local regulatory agency having jurisdiction over biomedical
operations or the manufacturing of Natural Alpha Interferon.

      5.3   Limitations.  Neither party makes any warranties, express or 
implied, other than those expressly made in this Agreement.  All other 
warranties, express or implied, including, without limitation, the implied 
warranties of merchantability and fitness for a particular purpose, are hereby 
disclaimed.

6.    Termination

      6.1   Rights to Terminate.  This Agreement may be terminated prior to the
scheduled end of the Term by a party (the "terminating party") as follows, by
notice as provided in Section 6.2:

            (a)   by either party, if the other party shall breach in any
material respect any of its material obligations under this Agreement and such
breach, if capable of being cured, shall not have been cured within 90 days 
after notice of such breach to the breaching party from the terminating party 
or, if such breach is capable of being cured but not within such 90-day period,
then within such period as is reasonably necessary to effect a cure so long as 
the breaching party diligently pursues such cure during such extended period; or

            (b)   by either party upon the entry of a decree or order by a court
having jurisdiction adjudging the other party a bankrupt or insolvent, or
approving a petition seeking reorganization, arrangement, adjustment, or
composition of or in respect of such other party, under federal bankruptcy law,
as now or hereafter constituted, or any other applicable federal or state
bankruptcy, insolvency, or other similar law, and the continuance of any such
decree or order unstayed and in effect for a period of 60 days; or the
commencement by such other party of a voluntary case under any such law, as now
or hereafter constituted, or the consent by it to the institution of bankruptcy
or insolvency proceedings against it, or the filing by it of a petition or 
answer or consent seeking reorganization or relief under any such law, or the 
consent by it to the filing of such petition or to the appointment of a 
receiver, liquidator, assignee, trustee, sequestrator, or similar official of it
or of any substantial part of its property, or the making by it of an assignment
for the benefit of creditors, or the admission by it in writing of its inability
to pay its debts generally as they become due, or the taking of corporate action
by such other party in furtherance of any such action.

      6.2   Notice of Termination.  Notice of termination in accordance with
Section 6.1 may be given by the terminating party, in the case of termination in
accordance with (a) Section 6.1(a), at any time after the end of the period
during which the other party has the right to cure the breach giving rise to
such right of termination and provided such breach has not been cured at the 
date of the giving of such notice or (b) Section 6.1(b), at any time after
occurrence of the event giving rise to such right of termination.

      6.3   Contested Termination.  If either party shall give notice of
termination of this Agreement pursuant to Section 6.2 and the other party shall,
within five days of receipt of such notice, commence legal proceedings 
contesting the terminating party's right to so terminate this Agreement, the 
parties shall continue to perform under this Agreement until the resolution of 
such controversy.

      6.4   Effect of Termination.  Termination, expiration, cancellation, or
abandonment of this Agreement through any means or for any reason shall not
relieve the parties of any obligation accruing prior thereto and shall be 
without prejudice to the rights and remedies of either party with respect to any
antecedent breach of any of the provisions of this Agreement.  The obligations
of the parties in Sections 3, 5.2(e), 6.4, 7, and 9, all obligations of the
parties set forth in Section 1 and in Appendix A hereto relating to the
registration and sale of shares of Common Stock and/or other securities, and any
representation or warranty made herein or in Appendix A shall survive any
termination of this Agreement.

7.    Indemnification

      7.1   Indemnification of ARC by ISI.  ISI agrees to indemnify, defend, and
hold ARC and its directors, officer, employees, volunteers, and agents harmless
from and against all liability, expense (including court costs and reasonable
attorneys' fees), and claims for bodily injury, death, or property damage, which
ARC may incur, suffer, become liable for, or which may be asserted or claimed
against ARC as a result of (a) the acts, errors, or omissions of ISI or its
directors, officers, employees, contractors, subcontractors, agents, customers,
or clients as a result of or while performing its obligations hereunder or
arising otherwise from the use, testing, or handling by ISI of ARC's buffycoats
or (b) the development, manufacture, sale, distribution, and use of Natural 
Alpha Interferon or any other product derived, in whole or in part, by ISI from 
ARC's buffycoats, including, but not be limited to, with respect to both clause
(a) and clause (b), (i) workers compensation claims of ISI's employees which may
arise from their handling of the buffycoats; (ii) claims ISI employees may 
personally make against ARC; (iii) any claim for damages arising from any 
subrogation attempt against ARC by ISI's insurers; and (iv) any claim against 
ARC, direct or indirect, arising in any manner from the provision by ISI to any 
customer of ISI, Natural Alpha Interferon, whether such claim  is made in a 
domestic court of law or foreign court of law;  provided, however, that the 
indemnity agreement contained in this Section 7.1 shall not apply to amounts 
paid in settlement of any such liability, expense, or claim if such settlement 
is effected by ARC or another person indemnified under this Section 7.1 without 
the consent of ISI (which consent shall not be unreasonably withheld), nor shall
ISI be responsible to ARC for any wrongful or negligent act or omission of ARC 
or its directors, officers, agents, or employees.

      7.2   Indemnification of ISI by ARC.  ARC agrees to indemnify, defend, and
hold ISI and its directors, officer, employees, volunteers, and agents harmless
from and against all liability, expense (including court costs and reasonable
attorneys' fees), and claims for bodily injury, death, or property damage, which
ISI may incur, suffer, become liable for, or which may be asserted or claimed
against ISI as a result of any negligent act or omission of ARC or its 
directors, officers, agents, or employees;  provided, however, that the 
indemnity agreement contained in this Section 7.2 shall not apply to amounts 
paid in settlement of any such liability, expense, or claim if such settlement 
is effected by ISI or another person indemnified under this Section 7.2 without 
the consent of ARC (which consent shall not be unreasonably withheld), nor shall
ARC be responsible to ISI for any wrongful or negligent act or omission of ISI 
or its directors, officers, agents, or employees.

      7.3   Indemnification Procedures. Promptly after receipt by an indemnified
party under  this Section 7 of notice of the commencement of any action, such
indemnified party will, if a claim in respect thereof is to be made against any
indemnifying party under this Section 7, deliver to the indemnifying party a
written notice of the commencement thereof and the indemnifying party shall have
the right to participate in, and, to the extent the indemnifying party so
desires, jointly with any other indemnifying party similarly noticed, to assume
the defense thereof with counsel mutually satisfactory to the parties; provided,
however, that an indemnified party (together with all other indemnified parties
which may be represented without conflict by one counsel) shall have the right
to retain one separate counsel, with the reasonable fees and expenses to be paid
by the indemnifying party, if representation of such indemnified party by the
counsel retained by the indemnifying party would be inappropriate due to actual
or potential differing interests between such indemnified party and any other
party represented by such counsel in such proceeding.  The failure to deliver
written notice to the indemnifying party within a reasonable time of the
commencement of any such action, if prejudicial to its ability to defend such
action, shall relieve such indemnifying party of any liability to the 
indemnified party  under this  Section 7, but the omission so to deliver written
notice to the indemnifying party will not relieve it of any liability that it 
may have to any indemnified party otherwise than under this Section 7.  
Notwithstanding the foregoing, this Section 7.3 shall not be applicable to any 
claim for indemnification under Section 7.1 or 7.2 to the extent that this 
Section 7.3 conflicts with or is inconsistent with the terms of any insurance 
policy of ARC or ISI covering such claim.

      7.4   Indemnification Not Exclusive.  The indemnification provided in this
Section 7 shall not be deemed exclusive of any other rights to which the parties
may be entitled.

      7.5   Relationship With Appendix A.  Each party agrees that with respect
to any  litigation or claim covered by the indemnifications in Appendix A,
Appendix A shall govern and not this Section 7.  Each party agrees that with
respect to any litigation or claim not covered by the indemnifications in
Appendix A, this Section 7 shall govern and not Appendix A.

8.    Definitions

      As used in this Agreement, the following terms shall have the following
meanings:

      8.1  "Affiliate" of any person shall mean any other person which controls,
is controlled by, or is under common control with such specified person, where
"control," including the terms "controlling" and "controlled," means the power
to direct the management and policies of a person, directly or indirectly,
whether through the ownership of securities or partnership or other ownership
interests, by contract, or otherwise.

      8.2   "Buffycoat Number" for any period shall mean (a) the number of
buffycoats that ISI is obligated to purchase from ARC, and ARC is obligated to
sell to ISI, in that period plus (b) the number of buffycoat that ARC sells to
ISI pursuant to Section 1.2(b)(ii)(C) in that period.

      8.3   "Confidential Information" shall mean all information and data which
is provided by either party to the other hereunder and either marked as
confidential or which the disclosing party otherwise informs the receiving party
is confidential, excluding any such information or data which (a) is known to 
the recipient before receipt thereof as evidenced by its written records, (b) is
or becomes available to the receiving party on a nonconfidential basis from a 
source which, to the receiving party's knowledge, is not prohibited from 
disclosing such information to the receiving party by a legal, contractual, or 
fiduciary obligation to the other party, or (c) is or becomes publicly available
other than as a result of a disclosure by the receiving party or its 
representatives or employees.

      8.4   "Formula Share Number" shall be   *    shares, subject to adjustment
from time to time pursuant to Section 1.3(g)(i).  

      8.5   "Market Price" on any date shall be deemed to be the average of the
daily Closing Price (as hereinafter defined) per share of Common Stock for the
30 consecutive trading days immediately preceding the day in question, after
appropriate adjustment for stock splits, stock dividends, and similar events
occurring within said 30-day period, and the "Closing Price" per share of Common
Stock for each day shall be (a) the closing sale price per share of Common Stock
on such day as reported on the composite tape of such national securities
exchange as shall then be the primary market for the Common Stock or (b) if the
Common Stock shall not then be listed or admitted to trading on any national
securities exchange or if the Common Stock shall then be so listed or admitted
to trading on a national securities exchange but that shall not then be the
primary market for the Common Stock, the closing sale price per share of the
Common Stock on such day as reported by Nasdaq or a comparable system or (c) if
not determinable as aforesaid, the mean between the highest and lowest bid 
prices reported on such day by market makers and dealers for the Common Stock 
listed as such by the National Quotation Bureau, Incorporated or any similar 
successor organization.

      8.6   "Sales Proceeds" shall be the amount received by ARC from the sale
of the First Shares or Second Shares, as the case may be, less all expenses of
sale incurred by ARC.

      8.7   "Term" shall mean the period from the date hereof to March 31, 1999
or such earlier date on which this Agreement may be terminated pursuant to
Section 6.

      8.8   "Year" shall mean each of the 12-month periods commencing April 1,
1997 and April 1, 1998. 

      8.9   All references herein to Sections and Schedules shall mean Sections
of and Schedules to this Agreement unless otherwise specified.

9.    Miscellaneous

      9.1   Payments.  All cash payments to be made hereunder shall be made by
check or wire transfer.  In the event a party shall reasonably dispute any
amounts claimed to be owed hereunder, such amounts shall not be deemed due until
such dispute is resolved, but any amounts not in dispute shall be deemed due.

      9.2   Further Actions.  At any time and from time to time, each party
agrees, at its expense, to take such actions and to execute and deliver such
documents as may be reasonably necessary to effectuate the purposes of this
Agreement.

      9.3   Notices.  Any notice or other communication required or permitted to
be given hereunder shall be in writing and shall be mailed by certified mail,
return receipt requested, or by Federal Express, Express Mail, or similar
overnight delivery or courier service or delivered (in person or by telecopy,
telex, or similar telecommunications equipment) against receipt to the party to
whom it is to be given at the address of such party set forth in the preamble to
this Agreement (or to such other address as the party shall have furnished in
writing in accordance with the provisions of this Section 9.3). Any notice given
to (a) ISI (fax number (908) 249-6895) shall be to the attention of Vice
President, Manufacturing with a copy to General Counsel or (b) ARC (fax number
703-312-5848) shall be to the attention of Vice President, Manufacturing with a
copy to General Counsel.  Any notice or other communication given by certified
mail shall be deemed given five days after the time of mailing thereof, except
for a notice changing a party's address which will be deemed given at the time
of receipt thereof.  Any notice given by other means permitted by this Section
9.3 shall be deemed given at the time of receipt thereof.

      9.4   Binding Effect. This Agreement shall be binding upon and shall inure
to the benefit of the parties hereto and their respective permitted assigns and
successors in interest.

      9.5   No Third Party Beneficiaries.  This Agreement does not create, and
shall not be construed as creating, any rights enforceable by any person not a
party to this Agreement (except as provided in Section 9.4).

      9.6   Headings.  The headings in this Agreement are solely for convenience
of reference and shall be given no effect in the construction or interpretation
of this Agreement.

      9.7   Counterparts.  This Agreement may be executed in any number of
counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same instrument.

      9.8   Assignment. Neither this Agreement nor any of the rights, interests,
or obligations hereunder shall be assigned by either party hereto without the
prior written consent of the other party; provided, that (a) the rights but not
obligations of any party herein may be assigned to one or more of such party's
Affiliates, (b) either party may cause any Affiliate to perform on its behalf 
any of such party's obligations, and (c) either party may assign all of its 
rights and obligations to any purchaser of all or substantially all of the 
assets of the part of such party's or its Affiliates' business which relates to 
the subject of this Agreement.  No assignment shall relieve either party of 
responsibility for the performance of any accrued obligation which such party 
then has hereunder. 

      9.9   Modification.  This Agreement and the Schedules hereto set forth the
entire understanding of the parties with respect to the subject matter hereof,
supersede all existing agreements among them concerning such subject matter
(including agreements between individual ARC blood centers and ISI), and may be
modified only by a written instrument duly executed by each party.

      9.10  Severability.  If any term or provision of this Agreement shall for
any reason be held invalid, illegal, or unenforceable in any respect, such
invalidity, illegality, or unenforceability shall not affect any other term or
provision hereof, and this Agreement shall be interpreted and construed as if
such term or provision, to the extent the same shall have been held to be valid,
illegal, or unenforceable, had never been contained herein.

      9.11  Waiver.  Any waiver by either party of a breach of any term of this
Agreement shall not operate as or be construed to be a waiver of any other 
breach of that term or of any breach of any other term of this Agreement.  The 
failure of a party to insist upon strict adherence to any term of this Agreement
on one or more occasions will not be considered a waiver or deprive that party 
of the right thereafter to insist upon strict adherence to that term or any 
other term of this Agreement.  Any waiver must be in writing.

      9.12  Jurisdiction.   Each of the parties hereby irrevocably consents to
the jurisdiction of the courts of the State of New Jersey or the Commonwealth of
Virginia and of any federal court located in such State or Commonwealth in
connection with any action or proceeding arising out of or relating to this
Agreement or a breach of this Agreement.  In any such action or proceeding, each
of the parties waives personal service of any summons, complaint, or other
process and agrees that service thereof may be made in accordance with Section
9.3.  Within 30 days after such service, or such other time as may be mutually
agreed upon in writing by the attorneys for the parties to such action or
proceedings or as may be ordered by the court, each of the parties shall appear
or answer such summons, complaint, or other process.  Should any of the parties
so served fail to appear or answer within such 30-day period or such extended
period, as the case may be, such party shall be deemed in default and judgment
may be entered by the other party against such party for the amount as demanded
in any summons, complaint, or other process so served.

      9.13  Public Announcements. Neither party shall issue any press release or
otherwise make any public statement with respect to this Agreement or any of the
transactions contemplated hereby without first consulting with and (unless such
press release or statement is required by applicable law or the requirements of
any listing agreement with any applicable stock exchange or inter-dealer
quotation system) obtaining the consent of the other party, which consent shall
not be unreasonably withheld.  ISI shall not use ARC's emblem without ARC's 
prior written consent.

IN WITNESS WHEREOF, the parties have caused this Agreement to be executed by
their duly authorized representatives as of the date first above written.

                                    AMERICAN NATIONAL RED CROSS

                                    By:   /s/ Niall M. Conway
                                          Niall M. Conway
                                          Vice President, Manufacturing


                                    INTERFERON SCIENCES, INC.

                                    By:   /s/ Lawrence M. Gordon
                                          Lawrence M. Gordon
                                          Chief Executive Officer



                                   Schedules


Schedule 1.2            Buffycoat Quantities

Schedule 1.3            Buffycoat Pricing

Schedule 1.3(e)         Illustration of Equity Provisions

Schedule 2.1            Buffycoat Testing Procedures





                                                       Schedule 1.2

                             BUFFYCOAT QUANTITIES


                            Quantity                        Minimum Days

Month  1                      *                                   *
Month  2                      *                                   *
Month  3                      *                                   *
Month  4                      *                                   *
Month  5                      *                                   *
Month  6                      *                                   *
Month  7                      *                                   *


            Minimum Purchases        Minimum Sales          Minimum Days

Month  8                *                 *                       *
Month  9                *                 *                       *
Month 10                *                 *                       *
Month 11                *                 *                       *
Month 12                *                 *                       *
Month 13                *                 *                       *
Month 14                *                 *                       *
Month 15                *                 *                       *
Month 16                *                 *                       *
Month 17                *                 *                       *
Month 18                *                 *                       *
Month 19                *                 *                       *
Month 20                *                 *                       *
Month 21                *                 *                       *
Month 22                *                 *                       *
Month 23                *                 *                       *
Month 24                *                 *                       *



                                                          Schedule 1.3

                              BUFFYCOAT PRICING


Buffycoat Number for Year           Price per Buffycoat


      *                                   *
      *                                   *
      *                                   *
      *                                   *
      *                                   *
      *                                   *


      
                                                       Schedule 1.3(e)

Illustration of the workings of the equity provisions of the agreement between
Interferon Sciences, Inc. and the American National Red Cross.

Assumptions (1)






      *






Calculations



      *







_________________________
(1)   For illustrative purposes only.  The actual numbers may differ materially
      from the numbers shown. 


                                                                Schedule 2.1

                           BUFFYCOAT TESTING PROCEDURES



                          *


                                      Appendix A
         

   This Appendix A to the Agreement, dated as of April 1, 1997, between 
Interferon Sciences, Inc., a Delaware corporation, and American National Red 
Cross, a charitable and not-for-profit corporation (the "Agreement"), is 
incorporated by reference in the Agreement as if fully set forth therein and for
all purposes shall be considered a part of the Agreement.  The terms defined in
the Agreement shall have their defined meanings when used herein.


1.    Expenses of Registration.

      All expenses, other than underwriting discounts and commissions, incurred
in connection with the Registration Statements or pursuant to Section 1.3(i)(iv)
or 1.3(j)(iv) of the Agreement, including (without limitation) all registration,
filing, and qualification fees, printers' and accounting fees, and fees and
disbursements of counsel for ISI, shall be borne by ISI.

2.    Indemnification.

      In the event any Shares or Transaction Consideration are registered under
a Registration Statement:
 
      (a)  ISI will indemnify and hold harmless ARC, any underwriter (as defined
in the Act) for ARC, and each person, if any, who controls ARC or such
underwriter within the meaning of the Act or the Securities Exchange Act of 
1934, as amended (the "1934 Act"), against any losses, claims, damages, or 
liabilities (joint or several) to which they may become subject under the Act, 
the 1934 Act, or other federal or state law, insofar as such losses, claims, 
damages, or liabilities (or actions in respect thereof) arise out of or are
based upon any of the following statements, omissions, or violations 
(collectively a "Violation"):  (i) any untrue statement or alleged untrue 
statement of a material fact contained in such Registration Statement, including
any preliminary prospectus or final prospectus contained therein or any 
amendments or supplements thereto, (ii) the omission or alleged omission to 
state therein a material fact required to be stated therein, or necessary to 
make the statements therein not misleading, or (iii) any violation or alleged 
violation by ISI of the Act, the 1934 Act, any state securities law or any rule 
or regulation promulgated under the Act, the 1934 Act, or any state securities 
law; and ISI will pay to ARC and each such underwriter or controlling person, as
incurred, any legal or other expenses reasonably incurred by them in connection 
with investigating or defending any such loss, claim, damage, liability, or 
action, including without limitation any governmental investigation relating to
any such alleged Violation; provided, however, that the indemnity agreement 
contained in this Section 2(a) shall not apply to amounts paid in settlement of 
any such loss, claim, damage, liability, or action if such settlement is 
effected without the consent of ISI (which consent shall not be unreasonably 
withheld), nor shall ISI be liable to any person entitled to be indemnified 
pursuant to this Section 2(a) for any such loss, claim, damage, liability, or
action to the extent that it arises out of or is based upon a Violation which 
occurs in reliance upon and in conformity with written information furnished by 
any person entitled to be indemnified pursuant to this Section 2(a) expressly 
for use in connection with such Registration Statement.  

      (b) ARC will indemnify and hold harmless ISI, each of its directors, each
of its officers who has signed such Registration Statement, each person, if any,
who controls ISI within the meaning of the Act, any underwriter, and any
controlling person of any such underwriter, against any losses, claims, damages,
or liabilities (joint or several) to which any of the foregoing persons may
become subject under the Act, the 1934 Act, or other federal or state law,
insofar as such losses, claims, damages, or liabilities (or actions in respect
thereto) arise out of or are based upon any Violation, in each case to the 
extent (and only to the extent) that such Violation occurs in reliance upon and
in conformity with written information furnished by ARC expressly for use in
connection with such Registration Statement; and ARC will pay to each person
entitled to be indemnified pursuant to this Section 2(b), as incurred, any legal
or other expenses reasonably incurred by them in connection with investigating
or defending any such loss, claim, damage, liability, or action, including
without limitation any governmental investigation relating to any such alleged
Violation; provided, however, that the indemnity agreement contained in this
Section 2(b) shall not apply to amounts paid in settlement of any such loss,
claim, damage, liability or action if such settlement is effected without the
consent of ARC, which consent shall not be unreasonably withheld; provided, 
that, in no event shall any indemnity obligation under this Section 2(b) 
(together with any obligation to contribute under Section 2(d)) exceed the gross
proceeds from the offering received by ARC.

      (c)   Promptly after receipt by an indemnified party under this Section 2
of notice of the commencement of any action (including any governmental action
or investigation), such indemnified party will, if a claim in respect thereof is
to be made against any indemnifying party under this Section 2, deliver to the
indemnifying party a written notice of the commencement thereof and the
indemnifying party shall have the right to participate in, and, to the extent 
the indemnifying party so desires, jointly with any other indemnifying party
similarly noticed, to assume the defense thereof with counsel mutually
satisfactory to the parties; provided, however, that an indemnified party
(together with all other indemnified parties which may be represented without
conflict by one counsel) shall have the right to retain one separate counsel,
with the reasonable fees and expenses to be paid by the indemnifying party, if
representation of such indemnified party by the counsel retained by the
indemnifying party would be inappropriate due to actual or potential differing
interests between such indemnified party and any other party represented by such
counsel in such proceeding.  The failure to deliver written notice to the
indemnifying party within a reasonable time of the commencement of any such
action, if prejudicial to its ability to defend such action, shall relieve such
indemnifying party of any liability to the indemnified party  under this Section
2, but the omission so to deliver written notice to the indemnifying party will
not relieve it of any liability that it may have to any indemnified party
otherwise than under this Section 2.

      (d)  To provide for just and equitable contribution, if (i) an indemnified
party makes a claim for indemnification pursuant to this Section 2 but is found
in a final judicial determination, not subject to further appeal, that such
indemnification may not be enforced in such case, even though this Section 2
expressly provides for indemnification in such case, or (ii) any indemnified or
indemnifying party seeks contribution under the Act, the 1934 Act, or otherwise,
then ISI (including for this purpose any contribution made by or on behalf of 
any director of ISI, any officer of ISI who signed any such Registration 
Statement, and any controlling person of ISI), as one entity, and ARC (including
for this purpose any contribution by or on behalf of a party indemnified under 
Section 2(a)), as a second entity, shall contribute to the losses, liabilities, 
claims, damages, and expenses whatsoever to which any of them may be subject, on
the basis of relevant equitable considerations such as the relative fault of ISI
and ARC in connection with the facts which resulted in such losses, liabilities,
claims, damages, and expenses.  The relative fault, in the case of an untrue
statement, alleged untrue statement, omission, or alleged omission, shall be
determined by, among other things, whether such statement, alleged statement,
omission, or alleged omission relates to information supplied by ISI or by ARC,
and the parties' relative intent, knowledge, access to information, and
opportunity to correct or prevent such statement, alleged statement, omission,
or alleged omission.  ISI and ARC agree that it would be unjust and inequitable
if the respective obligations of ISI and ARC for contribution were determined by
pro rata or per capital allocation of the aggregate losses, liabilities, claims,
damages, and expenses (even if ARC and the other parties indemnified under
Section 2(a) were treated as one entity for such purpose) or by any other method
of allocation that does not reflect the equitable considerations referred to in
this Section 2.  No person guilty of a fraudulent misrepresentation (within the
meaning of Section 11(f) of the Act) shall be entitled to contribution from any
person who is not guilty of such fraudulent misrepresentation.  For purposes of
this Section 2, each person, if any, who controls ARC or any underwriter within
the meaning of Section 15 of the Act or Section 20(a) of the 1934 Act and each
officer, director, partner, employee, and agent of ARC or such underwriter or
control person shall have the same rights to contribution as ARC or such
underwriter or control person and each person, if any, who controls ISI within
the meaning of Section 15 of the Act or Section 20(a) of the 1934 Act, each
officer of ISI who shall have signed any such registration statement, and each
director of ISI shall have the same rights to contribution as ISI, subject in
each case to the provisions of this Section 2. Anything in this Section 2 to the
contrary notwithstanding, no party shall be liable for contribution with respect
to the settlement of any claim or action effected without its written consent,
provided that such consent may not be unreasonably withheld.  This Section 2 is
intended to supersede any right to contribution under the Act, the 1934 Act, or
otherwise.

      (e)  The obligations of ISI and ARC under this Section 2 shall survive the
completion of any offering of Shares or Transaction Consideration in a
Registration Statement. 

3.    Reports Under the 1934 Act.

      With a view to making available to ARC the benefits of Rule 144 
promulgated under the Act and any other rule or regulation of the SEC that may 
at any time permit ARC to sell securities of ISI to the public without 
registration or pursuant to a registration on Form S-3, ISI agrees to:

      (a)   make and keep available adequate current public information with
respect to ISI as shall be required to comply with the provisions of Rule 
144(c), including by filing in a timely manner all reports and other documents 
required to be filed by ISI under the Act and the 1934 Act;

      (b)   furnish to ARC, so long as ARC owns any Shares or Transaction
Consideration, forthwith upon request (i) a written statement by ISI that it has
complied with the reporting requirements of the Act and the 1934 Act in such a
manner as to meet the requirements of Rule 144(c), or that it qualifies as a
registrant whose securities may be resold pursuant to Form S-3, (ii) a copy of
the most recent annual or quarterly report of ISI and such other reports and
documents so filed by ISI, and (iii) such other information as may be reasonably
requested in availing ARC of any rule or regulation of the Commission which
permits the selling of any such securities without registration or pursuant to
such form.
 
4.    Expenses.

      If any action at law or in equity is necessary to enforce or interpret the
terms of this Agreement, the prevailing party shall be entitled to reasonable
attorneys' fees, costs, and necessary disbursements in addition to any other
relief to which such party may be entitled.