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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549



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FORM 10-K/A

Amendment No. 1



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(Mark One)

|x | Annual Report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
|- | ------------------------------------------------------------------------------------



for the fiscal year ended December 31, 2004



or



| ̈ | Transition report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
|- | ----------------------------------------------------------------------------------------



for the transition period from  to



Commission file number 0-28748



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CLOSURE MEDICAL CORPORATION

(Exact name of registrant as specified in its charter)



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|                                                               |  |                                     
|-------------------------------------------------------------- |  | ------------------------------------
|Delaware                                                       |  | 56-1959623                          
|(State or other jurisdiction of incorporation or organization) |  | (I.R.S. Employer Identification No.)
|                                                               | 
|5250 Greens Dairy Road Raleigh, North Carolina                 |  | 27616                               
|(Address of principal executive offices)                       |  | (Zip Code)                          



Registrants
telephone number, including area code: (919) 876-7800



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Securities registered pursuant to Section 12(b) of the Act:



|                    |  |                                          
|------------------- |  | -----------------------------------------
|Title of each class |  | Name of each exchange on which registered
|None                |  | None                                     



Securities
registered pursuant to Section 12(g) of the Act:



Common
Stock, par value $.01 per share

(Title of class)



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Indicate by
check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such
reports), and (2) has been subject to such filing requirements for the past 90 days.    Yes  x    No ̈



Indicate
by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to the best of registrants knowledge, in the definitive proxy statement incorporated by reference in
Part III of this Annual Report on Form 10-K or any amendment to this Annual Report on Form 10-K.  x



Indicate by check mark whether the registrant is an accelerated filer (as defined in Rule 12b-2 of the Act).    Yes  x    No ̈



As of June 30, 2004 the aggregate market value of the voting and non-voting Common Stock held by non-affiliates of the registrant was
$219,166,031 based upon the closing price of the Common Stock as reported on the Nasdaq National Market. Shares of common stock held by each officer and director and by each person who owns five percent or more of the outstanding common stock have
been excluded from this calculation as such persons may be considered to be affiliated with the Company.



As of April 22, 2005, the number of shares of Common Stock outstanding was 14,482,671.



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This amendment to Closure Medical Corporations (or Closure) Form 10-K for the fiscal year ended
December 31, 2004 is being filed to provide the information required by Part III of Form 10-K.



PART III



ITEM 10. DIRECTORS
AND EXECUTIVE OFFICERS OF THE REGISTRANT.



|                           |  |     |  |                                                   
|-------------------------- |  | --- |  | --------------------------------------------------
|Name                       |  | Age |  | Position                                          
|J. Daniel Cole (1) (3)     |  | 58  |  | Chairman                                          
|Daniel A. Pelak            |  | 53  |  | Director and President and Chief Executive Officer
|Richard W. Miller (1) (3)  |  | 64  |  | Director                                          
|James E. Niedel (1)        |  | 61  |  | Director                                          
|Rolf D. Schmidt            |  | 72  |  | Director                                          
|Stephen I. Shapiro (2) (3) |  | 60  |  | Director                                          
|Randy H. Thurman (2)       |  | 55  |  | Director                                          

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|(1) | Member of the Audit Committee of Board of Directors
|--- | ---------------------------------------------------

|(2) | Member of the Compensation Committee of the Board of Directors
|--- | --------------------------------------------------------------

|(3) | Member of the Nominating and Governance Committee of the Board of Directors
|--- | ---------------------------------------------------------------------------



J. Daniel Cole has served as a director of Closure since June 2003 and has served as Chairman of the Board since June 2004. Since 1997, he has served as a general partner
at Spray Venture Partners in Boston, which focuses exclusively on the healthcare technology market. Prior to joining Spray Venture Partners, he served in many executive roles, including Senior Vice President and Group President of the vascular
businesses at Boston Scientific Corporation from 1995 to 1997 and President and Chief Operating Officer of SciMed Life Systems, Inc. from 1993 to 1995. From 1982 to 1993, he held several positions with Baxter International, Inc., most recently as
President of the Edwards Critical Care Division. Mr. Cole holds a B.S. in Aeronautical Engineering from the University of Kansas, an M.S. in Aeronautical Engineering from the United States Navy Post-Graduate School and an M.B.A. from the University
of California, Los Angeles. Mr. Cole serves on the Board of Directors of Thoratec Corporation.



Daniel A. Pelak has served as a director and as President and Chief Executive Officer of Closure since September 2002. Prior to joining Closure, Mr. Pelak spent 26 years with Medtronic, Inc. During his career, he held
positions in sales, sales management, marketing, and general management. Immediately prior to joining Closure, he was the Vice President and General Manager of Medtronics Perfusion Systems Division. From March 2000 until January 2002, he was
the Vice President and General Manager of Medtronics Cardiac Surgery Technologies Division. From 1992 to 2000, Mr. Pelak managed progressively larger sales and marketing operations within the cardiovascular areas of Medtronic, including Vice
President Cardiovascular Marketing and Vice President U.S. Cardiac Surgery Business. Prior to 1992, he held the position of Vice President and General Manager of Medtronics Nortech Division. Mr. Pelak holds a B.S. degree from Pennsylvania
State University.



Richard W. Miller has served as a director of Closure since
August 1997. From 1993 to 1997, he served as Senior Executive Vice President and Chief Financial Officer of AT&T. Previously, he was Chief Executive Officer of Wang Laboratories from 1989 to 1993, and prior to that, he held executive positions
at General Electric Company and RCA. Mr. Miller holds an M.B.A. from Harvard Business School and a B.B.A. degree in Economics from Case Western Reserve University.



James E. Niedel, M.D., Ph.D. has served as a director of Closure since October 2001. Dr. Niedel joined the Sprout Group as a venture partner
in May 2002. Prior to that appointment, he was Chief Science and Technology Officer of GlaxoSmithKline plc. From 1988 to 2000, Dr. Niedel served as Vice President of Research and Senior Vice President for Research and Development at Glaxo Inc., and
as a member of the Board of Directors of Glaxo Wellcome plc with responsibility for worldwide Research and Development, Information Systems and Product Strategy. Before joining the pharmaceutical industry he was Professor of Medicine and Chief of
Clinical Pharmacology at Duke University Medical School. Dr. Niedel holds a bachelors degree in psychology from the University of Wisconsin and doctorates of medicine and biochemistry from the University of Miami. He is a Fellow of the Royal
College of Physicians (London) and a member of the Board of Directors of Sirna Therapeutics, Inc.



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Rolf D. Schmidt, a co-founder of Closure in 1990, has been a director since February 1996, serving as Chairman of the
Board of Directors of Closure from February 1996 to December 1999. Mr. Schmidt has served as Chief Executive Officer and Chairman of Performance Sports Apparel, Inc. since 1995. In 1986, a significant portion of the business of Sharpoint, Inc., a
developer and manufacturer of surgical needles and sutures co-founded by Mr. Schmidt and his brother, F. William Schmidt, was sold to its primary distributor, Alcon Laboratories, Inc. In 1991, the remainder of such business was sold to a management
group. Since 1990, Mr. Schmidt has invested primarily in and devoted substantial time and attention to healthcare-related entities, including Closure.



Stephen I. Shapiro has served as a director of Closure since October 2003. Currently, Mr. Shapiro serves as a technology partner at Advanced Technology Ventures and an
advisor at Galen Associates. From 1982 to 1999, Mr. Shapiro was a managing director of The Wilkerson Group, a leading management consulting firm to pharmaceutical, medical device and diagnostic companies. Prior to 1982, Mr. Shapiro held a variety of
technical management and strategic planning positions with Becton Dickinson and Company and Union Carbide Clinical Diagnostics. Mr. Shapiro holds a B.S. in chemical engineering from the Massachusetts Institute of Technology and an M.S. in chemical
engineering from the University of California at Berkeley. Mr. Shapiro serves on the Board of Directors of Novoste Corporation and Specialized Health Products International.



Randy H. Thurman has served as a director of Closure since May 1996. In April 2001, Mr. Thurman became Chairman and Chief Executive Officer
of Viasys Healthcare Inc., a global healthcare technology company focusing on respiratory and neuro science products. Mr. Thurman previously was Chief Executive Officer of Strategic Reserves, LLC , a healthcare technology consulting and investment company. From 1993 to 1996, Mr.
Thurman was Chairman and CEO of Corning Life Sciences, a wholly-owned subsidiary of Corning Inc. which specializes in pharmaceutical testing, clinical diagnostics and disease state management. From 1984 to 1993, Mr. Thurman was an executive with
Rhône-Poulenc Rorer, most recently as President and a director. Mr. Thurman holds an M.A. degree from Webster University and a B.A. degree from Virginia Polytechnic Institute. Mr. Thurman serves on the Board of Directors of Valeant
Pharmaceuticals International.



Code of Conduct



We have adopted a Corporate Code of Conduct that applies to, among others, the Chairman,
President and Chief Executive Officer, the Vice President of Finance and Chief Financial Officer and the Controller as required by Section 406 of the Sarbanes Oxley Act of 2002. The Corporate Code of Conduct is posted on our website at
http://www.closuremed.com.



Audit Committee



We have a standing Audit Committee that, among other things, was established by the Board of
Directors for the purpose of overseeing our accounting and financial reporting processes and audits of our financial statements. The members of our Audit Committee are Messrs. Richard W. Miller, J. Daniel Cole and James E. Niedel. Mr. Miller is the
Chairman of our Audit Committee.



Audit Committee Financial Expert



Our Board of Directors has determined that Richard W. Miller, the
Chairman of our Audit Committee, is an audit committee financial expert as defined in Securities and Exchange Commission regulations. Mr. Miller is independent within the meaning of the rules of the Nasdaq Stock Market, Inc.



Section 16(a) Beneficial Ownership Reporting Compliance



Section 16(a) of the Securities Exchange Act of 1934, as amended, requires our directors and
executive officers, and persons who own more than ten percent of our common stock, to file reports of ownership of our securities and changes in ownership with the Securities and Exchange Commission. To our knowledge, based solely on a review of the
copies of such reports furnished to us and representations of these persons that no other reports were required, during the year ended December 31, 2004, all of our directors, executive officers and greater than 10% stockholders complied with all
Section 16(a) filing requirements.



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ITEM 11. EXECUTIVE COMPENSATION.



The following table provides information concerning the annual and long-term compensation of (1) Closures Chief
Executive Officer, (2) the four most highly compensated executive officers other than the Chief Executive Officer who were executive officers as of December 31, 2004 and (3) one individual that would have been one of the four most compensated
executive officers if she had been an executive officer as of December 31, 2004 (collectively, the Named Executive Officers).



Summary Compensation Table



|                                                                       |  |                     |  |                        |  |                               |  |                                  |  |                                                        |  |                   
|---------------------------------------------------------------------- |  | ------------------- |  | ---------------------- |  | ----------------------------- |  | -------------------------------- |  | ------------------------------------------------------ |  | ------------------
|                                                                       |  | Annual Compensation |  | Long-Term Compensation |  | All Other Compensation ($)(3)
|Name and Principal Position                                            |  | Year                |  | Salary($)              |  | Bonus($)(1)                   |  | Other Annual Compensation ($)(2) |  | Number of Securities Underlying Options Awarded (#)(1) | 
|Daniel A. Pelak (4) Director and President and Chief Executive Officer |  | 200420032002        |  | 401,423350,000110,385  |  | 273,000100,000               |  | 59,73668,27515,727               |  | 60,000250,000400,000                                   |  | 29,16523,9755,862 
|                                                                       |  |                     |  |                        |  |                              
|William M. Cotter Vice President of Manufacturing and Operations       |  | 200420032002        |  | 239,223219,663207,235  |  | 135,300114,33395,550          |  |                               |  | 25,00015,00030,000                                     |  | 19,17919,77317,508
|                                                                       |  |                     |  |                        |  |                              
|Benny Ward Vice President of Finance and Chief Financial Officer       |  | 200420032002        |  | 238,646204,462184,423  |  | 123,615109,33578,000          |  |                               |  | 25,00020,00040,000                                     |  | 14,15512,46511,314
|                                                                       |  |                     |  |                        |  |                              
|Debra L. Pawl (5) Vice President and General Counsel                   |  | 200420032002        |  | 228,652194,798187,212  |  | 118,17093,93885,313           |  |                               |  | 15,00040,000                                          |  | 11,71311,8859,957 
|                                                                       |  |                     |  |                        |  |                              
|Jerry Y. Jonn Vice President of Research                               |  | 200420032002        |  | 208,077169,664157,327  |  | 103,02085,99673,125           |  |                               |  | 18,00015,00030,000                                     |  | 21,58515,63414,750
|                                                                       |  |                     |  |                        |  |                              
|James F. Buck Vice President of Marketing                              |  | 200420032002        |  | 208,846131,539        |  | 85,928                      |  | 18,90783,609                    |  | 18,000100,000                                         |  | 16,3439,064      

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|(1) | Cash bonuses and stock option awards are reflected in the year of payment or grant.
|--- | -----------------------------------------------------------------------------------



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|(2) | Represents moving and relocation expenses, as well as certain expense allowances, in accordance with the individuals employment agreement.
|--- | -------------------------------------------------------------------------------------------------------------------------------------------

|(3) | Represents Company-paid insurance premiums (life, disability and medical) and 401(k) retirement plan matching contributions.
|--- | ----------------------------------------------------------------------------------------------------------------------------

|(4) | Mr. Pelak was appointed as Chief Executive Officer in September 2002 with an annual base salary of $350,000.
|--- | ------------------------------------------------------------------------------------------------------------

|(5) | Ms. Pawl resigned as Closures General Counsel in October 2004.
|--- | ---------------------------------------------------------------



STOCK OPTION INFORMATION



The following table sets forth information concerning the grant of stock options during 2004 to the Named Executive Officers.



Option Grants in 2004



|                  |  |                                                         |  |                                                                                                 |  |                               |  |                |  |         |  |          
|----------------- |  | ------------------------------------------------------- |  | ----------------------------------------------------------------------------------------------- |  | ----------------------------- |  | -------------- |  | ------- |  | ---------
|                  |  | Individual Grants                                       |  | Potential Realizable ValueAt Assumed Annual Rates ofStock Price Appreciationfor Option Term
(3)
|Name              |  | Number of Securities Underlying Options Granted (#) (1) |  | % of Total Options Granted to Employees in 2004 (2)                                             |  | Exercise Or Base Price ($/Sh) |  | ExpirationDate |  | 5% ($)  |  | 10% ($)  
|Daniel A. Pelak   |  | 60,000                                                  |  | 11.7                                                                                            |  | 19.05                         |  | 12/20/14       |  | 718,827 |  | 1,821,648
|William M. Cotter |  | 25,000                                                  |  | 4.9                                                                                             |  | 19.05                         |  | 12/20/14       |  | 299,511 |  | 759,020  
|Benny Ward        |  | 25,000                                                  |  | 4.9                                                                                             |  | 19.05                         |  | 12/20/14       |  | 299,511 |  | 759,020  
|Jerry Y. Jonn     |  | 18,000                                                  |  | 3.5                                                                                             |  | 19.05                         |  | 12/20/14       |  | 215,648 |  | 546,494  
|James F. Buck     |  | 18,000                                                  |  | 3.5                                                                                             |  | 19.05                         |  | 12/20/14       |  | 215,648 |  | 546,494  

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|(1) | Options granted in 2004 will vest in four equal installments beginning on the first anniversary of the grant date.
|--- | ------------------------------------------------------------------------------------------------------------------

|(2) | Based on 513,600 options granted to employees in 2004.
|--- | ------------------------------------------------------

|(3) | The potential realizable value is based on the term of the option at its time of grant (ten years in the case of the options listed above). It is calculated by assuming that the
stock price on the date of grant appreciates at the indicated annual rate, compounded annually for the entire term of the option, and that the option is exercised and the underlying shares sold on the last day of its term for the appreciated stock
price. These amounts represent certain assumed rates of appreciation only, in accordance with the rules of the SEC, and do not reflect Closures estimate or projection of future stock price performance. Actual gains, if any, are dependent on
the actual future performance of Closures Common Stock, and no gain to the optionee is possible unless the stock price increases over the option term, which will benefit all stockholders.
|--- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



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The following table sets forth information concerning stock option exercises during 2004 as well as options outstanding
as of December 31, 2004.



Aggregated Option Exercises in 2004
and 2004 Year-End Option Values



|                  |  |                           |             |                |               |                                                                               |             |                                                                         |               |           |  |          
|----------------- |  | ------------------------- | ----------- | -------------- | ------------- | ----------------------------------------------------------------------------- | ----------- | ----------------------------------------------------------------------- | ------------- | --------- |  | ---------
|Name              |  | SharesAcquiredon Exercise |             | Value Realized |               | Number of Securities UnderlyingUnexercised Options at Fiscal Year-End (#) (2) |             | Value of Unexercised In-the-Money Optionsat Fiscal Year-End ($) (1) (2)
|                  |  |                           | Exercisable |                | Unexercisable |                                                                               | Exercisable |                                                                         | Unexercisable
|                  |  | (#)                       |             | ($)            |               |                                                                               |             |                                                                         |               |           |  |          
|Daniel A. Pelak   |  |                          |             |               |               | 262,500                                                                       |             | 447,500                                                                 |               | 1,219,500 |  | 1,829,500
|William M. Cotter |  |                          |             |               |               | 151,750                                                                       |             | 54,250                                                                  |               | 240,560   |  | 52,560   
|Benny Ward        |  |                          |             |               |               | 119,478                                                                       |             | 74,000                                                                  |               | 428,284   |  | 95,080   
|Debra L. Pawl     |  | 23,000                    |             | 84,151         |               | 132,550                                                                       |             |                                                                        |               | 69,077    |  |         
|Jerry Y. Jonn     |  | 8,800                     |             | 115,581        |               | 106,150                                                                       |             | 63,250                                                                  |               | 118,436   |  | 49,410   
|James F. Buck     |  |                          |             |               |               | 21,000                                                                        |             | 97,000                                                                  |               | 126,240   |  | 513,060  

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|(1) | Calculated on the basis of the closing price of $19.50 per share of Common Stock on December 31, 2004 as quoted on the Nasdaq National Market.
|--- | ----------------------------------------------------------------------------------------------------------------------------------------------

|(2) | Pursuant to the merger agreement with Johnson & Johnson, upon completion of the pending merger, each option outstanding immediately prior to the completion of the merger will be
canceled and the holder of that option will be entitled to receive a single lump sum cash payment equal to the number of shares of our common stock for which the option was exercisable, multiplied by the excess, if any, of the $27.00 per share
merger consideration over the per share exercise price of the option. No payment will be made with respect to options that have per share exercise prices equal to or greater than $27.00.
|--- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Director Compensation



Directors who are employees of Closure receive no compensation for serving on the Board of Directors. Each non-employee director receives
$1,500 per day for each regularly scheduled meeting of the Board of Directors attended either in person or participated in telephonically. In addition, effective in December 2004 each non-employee director receives $750 for each Committee meeting in
which such director participates and for each special meeting of the Board of Directors in which such director participates telephonically. Non-employee directors of Closure do not receive annual cash compensation, except in the case of the
Chairman, Mr. Cole, who receives a cash retainer of $10,000 per quarter. Further, each non-employee director receives a one-time grant of options to purchase 60,000 shares of Common Stock upon initial election or appointment to the Board of
Directors, with 50% of the options vesting immediately and 25% vesting on each of the next two anniversaries of the grant date, if the director continues to be a member of the Board of Directors on the relevant anniversary date. Any director may
receive additional options as determined by the Compensation Committee and subject to the approval of the Board. In 2004, the Board approved a grant of 30,000 options to Mr. Cole for his services as Chairman. If a director retires from the Board or
in the event of death or disability, in general, unvested options held by the director at the time of the directors departure from the Board will become fully vested. In addition, in such event, each director will generally have up to three
years to exercise vested options.



Employment Agreements



Daniel A. Pelak, William M. Cotter, Benny Ward, Jerry Y. Jonn and James F. Buck entered into
employment agreements with Closure commencing in August 2002, June 1997, January 2004, July 2001, and April 2003, respectively. Mr. Pelaks employment agreement has a three-year term beginning on its commencement and Mr. Cotters has a
two-year term beginning on its commencement. Messers Ward, Jonn and Buck have agreements with a one-year term beginning on their commencement. Each of the employment agreements provides for automatic one-year



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extensions unless 60 days prior notice is given by either party, except for Mr. Pelaks agreement, which requires 180 days prior notice and
Mr. Bucks agreement, which provides for automatic one-year extensions unless 180 days notice is given by Closure or unless 60 days prior notice is given by Mr. Buck. The agreements provide for annual base salaries for Pelak,
Cotter, Ward, Jonn and Buck of not less than $350,000, $150,000, $228,165, $150,000 and $190,000, respectively, which salaries may be increased as determined by the Compensation Committee or the Board of Directors. Each agreement also provides for
an annual bonus ranging from 20% to 60% of base salary to be awarded based on performance milestones to be established for each calendar year by the Compensation Committee based on the recommendation of the Chief Executive Officer, except for Mr.
Pelak who may receive up to 75% of base salary.



Upon entering into his
employment agreement with Closure, Mr. Pelak was granted options to purchase 400,000 shares of Common Stock under the Equity Compensation Plan at an exercise price of $14.86. Further, Mr. Pelaks employment agreement provided that he would be
entitled to receive options to purchase an additional 200,000 shares upon the satisfaction of certain conditions. Those conditions were satisfied and Mr. Pelak was granted the additional options in April 2003 at an exercise price of $13.67. Both
option grants have a term of ten years and, provided employment has not been terminated for cause (as defined in his employment agreement), vest in four equal annual installments, commencing on the first anniversary of the date of grant.
Mr. Cotter, in connection with his employment agreement, was granted options to purchase 40,000 shares of Common Stock under the Equity Compensation Plan at an exercise price of $18.25 per share. In connection with their employment agreements,
Closure granted to Messers Jonn and Buck options to purchase 40,000 and 80,000 shares of Common Stock under the Equity Compensation Plan at an exercise price of $20.05 and $11.61 per share, respectively. All options have a term of ten years
and, vest in four or five equal annual installments, commencing on the first anniversary of the date of grant.



If, following a change in control (as defined in his employment agreement), Mr. Pelak is terminated other than for cause, disability, or death or terminates his employment for
good reason (all as defined in his employment agreement), he will be entitled to receive all accrued base salary and incentive compensation earned up to the date of his termination, benefits for a specified period of time and a lump sum
cash payment equal to three times the sum of his then current base salary plus his target bonus for the year in which the change occurs. If, following a change in control (as defined in his employment agreement), Mr. Cotter is terminated
other than for cause (as defined in his employment agreement) or terminates his employment for good reason (as defined in his employment agreement), he will be entitled to receive all accrued and any pro rata incentive
compensation to the date of termination and a continuation of his then current annual salary, incentive compensation and benefits for three years after such termination. If, following a change in control (as defined in his employment
agreement), Mr. Ward is terminated other than for cause (as defined in his employment agreement) or terminates his employment for good reason (as defined in his employment agreement), he will be entitled to receive all
accrued and any pro rata incentive compensation to the date of termination, a lump sum cash payment equal to two times the sum of his then current annual salary and incentive compensation for the year of termination and benefits for two years after
such termination. If, following a change in control (as defined in their respective employment agreements), Messers Jonn and Buck are terminated other than for cause (as defined in their respective employment
agreements) or terminate their employment for good reason (as defined in their respective employment agreements), they will be entitled to receive all accrued and any pro rata incentive compensation to the date of termination and a
continuation of the then current annual salary, incentive compensation and benefits for one year after such termination. In the event of termination for cause, each of Messrs. Cotter, Ward, Jonn and Buck is entitled to a continuation of
base salary, incentive compensation and benefits for a period of one year. Pursuant to each of these employment agreements, Closure has agreed to indemnify such executive officers to the maximum extent permitted by applicable law against all costs,
charges and expenses incurred by each in connection with any action, suit or proceeding to which he may be a party or in which he may be a witness by reason of his being an officer, director or employee of Closure or any subsidiary or affiliate of
Closure. Each of the foregoing executive officers has agreed not to compete with Closure for two years after termination of their employment with Closure.



In connection with the execution of the Merger Agreement on March 3, 2005, Johnson & Johnson and Closure entered into letter agreements (the Letter
Agreements) with Messers Pelak, Cotter, Ward, Jonn and Buck (collectively, the Executive Officers) modifying such individuals rights and obligations under their employment agreements with Closure. The Letter Agreements
will be void and of no further force and effect if the Merger Agreement is terminated prior to the consummation of the Merger.



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The Letter Agreements amend the employment agreements of all of the Executive Officers to (i) modify the benefits that
Closure will be required to provide following the termination of the Executive Officers employment with Closure and (ii) provide that if the Executive Officer remains in continuous employment with Closure through the expiration of a certain
period of time immediately following consummation of the Merger (in the case of Messrs. Pelak and Ward, three months, and in the case of the other Executive Officers, 12 months), he will receive a bonus (the Retention Bonus) in an amount
equal to the cash severance payment that otherwise would have been payable in accordance with the terms of the Executives Officers employment agreement had the Executive Officer been involuntarily terminated or had resigned for
good reason immediately following consummation of the Merger. The Retention Bonus is conditioned upon the Executive Officer providing a customary waiver and release of claims.



The Letter Agreements of the Executive Officers other than Messrs. Pelak and Ward provide that (i) the definition of good reason
contained in the employment agreements is modified to exclude a change in duties and responsibilities due to the fact that Closure is no longer an independently publicly held company and has become a subsidiary of another company, (ii) the Executive
Officer waives his rights to severance benefits in the event he is terminated for cause as defined in the employment agreements, (iii) to the extent the Executive Officer remains employed with Closure during the twelve-month period
immediately following the consummation of the Merger, the Executive Officer will have the same base salary rate, the same title and the same general duties and responsibilities as in effect on the date of the execution of the Merger Agreement, (iv)
to the extent the Executive Officer remains employed through the applicable payment date, the Executive Officer is eligible to receive an annual bonus with respect to the 2005 calendar year in an amount not less than the annual bonus paid in
calendar year 2004 and (v) the Executive Officers will be granted stock options to acquire shares of Johnson & Johnson common stock, and in the case of Mr. Jonn, he will receive a cash bonus in addition to such stock options.



On October 28, 2004, Closure entered into a Separation of Employment Agreement and General
Release (the Separation Agreement) with Debra L. Pawl in connection with the termination of her employment as Closures Vice President and General Counsel. Pursuant to the terms of the Separation Agreement, Closure agreed to pay Ms.
Pawl (a) her base salary at its current rate through October 28, 2005 in accordance with our standard payroll procedures, (b) an incentive bonus for the 2004 calendar year in the amount of $104,890 on the date that other executives were paid their
bonuses for the 2004 calendar year, and (c) a pro-rata incentive bonus in the amount of $87,373 for the first ten months of the 2005 calendar year, payable in 26 equal installments over the twelve-month period beginning on October 29, 2004 and
ending on October 28, 2005. In addition, Closure agreed to pay the full premiums associated with Ms. Pawls continued participation in our benefit programs in which she participated at the time of the termination of her employment (other than
our 401(k) plan). Finally, the Separation Agreement provided for various treatment of outstanding stock options held by Ms. Pawl on the date of the termination of her employment based on whether such options were vested or unvested and whether the
exercise price of such options were above or below the market price of our common stock on such date. As a condition to receiving the benefits under the Separation Agreement, Ms. Pawl has, among other things, released us from any past, present and
future alleged claims.



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ITEM 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT.



The following table and notes set forth certain information with respect to the beneficial
ownership of Common Stock as of April 22, 2005 by (i) each stockholder known by Closure to own beneficially more than 5% of Closures Common Stock, (ii) each of the executive officers named in the Summary Compensation Table, (iii) each of
Closures directors and (iv) all directors and executive officers of Closure as a group. The information in the table is based upon information furnished to us by such persons or entities.



|                                                                 |  |                              |  |        
|---------------------------------------------------------------- |  | ---------------------------- |  | -------
|                                                                 |  | SharesBeneficially Owned (1)
|Name of Beneficial Owner                                         |  | Number                       |  | Percent
|F. William Schmidt (2)(8)                                        |  | 3,288,275                    |  | 22.7   
|Rolf D. Schmidt (3)(8)                                           |  | 3,058,375                    |  | 21.1   
|Endowment Capital, L.P. (4)                                      |  | 1,157,732                    |  | 8.0    
|Gabelli Asset Management Inc. (5)                                |  | 799,424                      |  | 5.5    
|Daniel A. Pelak (6) (8)                                          |  | 323,500                      |  | 2.2    
|Randy H. Thurman (8)                                             |  | 188,044                      |  | 1.3    
|Richard W. Miller (8)                                            |  | 184,512                      |  | 1.3    
|William M. Cotter (8)                                            |  | 170,776                      |  | 1.2    
|Benny Ward (8)                                                   |  | 154,007                      |  | 1.1    
|Debra L. Pawl (7)(8)                                             |  | 121,600                      |  | *      
|Jerry Y. Jonn (8)                                                |  | 117,400                      |  | *      
|James E. Niedel (8)                                              |  | 120,000                      |  | *      
|J. Daniel Cole (8)                                               |  | 67,500                       |  | *      
|Stephen I. Shapiro (8)                                           |  | 45,000                       |  | *      
|James F. Buck (8)                                                |  | 44,767                       |  | *      
|All directors and executive officers as a group (14 persons) (9) |  | 4,617,885                    |  | 31.9   

---

|* | Less than 1%.
|- | -------------

|(1) | Nature of ownership consists of sole voting and investment power unless otherwise indicated. Includes shares of Common Stock issuable upon the exercise of stock options exercisable
within 60 days of April 22, 2005.
|--- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|(2) | The address of the stockholder is 534 Ridge Avenue, Ephrata, PA 17522. Includes (a) 2,236,945 shares held by Triangle Partners, L.P., a limited partnership of which F. William
Schmidt is the sole general partner, for which shares he is deemed to have sole voting and investment power; (b) 539,912 shares held by OMI Partners, L.P., a limited partnership of which F. William Schmidt and Rolf D. Schmidt are the sole general
partners, for which shares they are deemed to share voting and investment power; and (c) 50,000 shares held by F. William Schmidts spouse, for which shares he is deemed to share voting and investment power.
|--- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



9



---

|(3) | The address of the stockholder is 205 Sweitzer Road, Sinking Spring, PA 19608. Includes (a) 2,047,445 shares held by Cacoosing Partners, L.P., a limited partnership of which Rolf D.
Schmidt is the sole general partner, for which shares he is deemed to have sole voting and investment power; (b) 539,912 shares held by OMI Partners, L.P., a limited partnership of which Rolf D. Schmidt and F. William Schmidt are the sole general
partners, for which shares they are deemed to share voting and investment power; and (c) 140,000 shares owned jointly by Rolf D. Schmidt and his spouse, for which shares he is deemed to share voting and investment power.
|--- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|(4) | The address of the stockholder is 1105 N. Market Street, 15thFloor, Wilmington, DE 19081.
|--- | -----------------------------------------------------------------------------------------

|(5) | This amount is reflected in a report on Schedule 13D that was filed on April 11, 2005 by the stockholder and certain of its subsidiaries and affiliates. The address of the
stockholder is One Corporate Center, Rye, NY 10580.
|--- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|(6) | Includes 5,000 shares held in a family trust for which Mr. Pelak and his spouse are the sole trustees and beneficiaries.
|--- | ------------------------------------------------------------------------------------------------------------------------

|(7) | Ms. Pawl resigned as Closures General Counsel in October 2004.
|--- | ---------------------------------------------------------------

|(8) | Except as otherwise noted in footnote (2) or (3) the address of the stockholder is c/o Closure Medical Corporation, 5250 Greens Dairy Road, Raleigh, NC 27616. Includes the following
shares of Common Stock issuable upon the exercise of stock options exercisable within 60 days of April 22, 2005: F. William Schmidt151,044; Rolf D. Schmidt151,044; Daniel A. Pelak312,500; Randy H. Thurman182,044; Richard W.
Miller177,512; William M. Cotter161,500; Benny Ward142,478; Debra L. Pawl118,000; Jerry Y. Jonn115,900; James E. Niedel120,000; J. Daniel Cole67,500; Stephen I. Shapiro45,000; and James F.
Buck42,000.
|--- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|(9) | Includes 1,655,668 shares of Common Stock issuable upon the exercise of stock options exercisable within 60 days of April 22, 2005.
|--- | -----------------------------------------------------------------------------------------------------------------------------------



On March 3, 2005, Closure, Johnson & Johnson and Holden Merger Sub, Inc., a wholly owned
subsidiary of Johnson & Johnson (Merger Sub), entered into an Agreement and Plan of Merger (the Merger Agreement). The Merger Agreement provides for a business combination whereby Merger Sub will merge with and into
Closure (the Merger). As a result of the Merger, the separate corporate existence of Merger Sub will cease and Closure will continue as the surviving corporation in the Merger. At the effective time of the Merger, each share of common
stock of Closure (other than shares owned by Closure, Johnson & Johnson and Merger Sub) will be converted into the right to receive $27.00 in cash, without interest. Each outstanding Company stock option at the time of the closing will be
cancelled in the Merger and the holder thereof shall be entitled to an amount of cash, without interest, equal to the difference between $27.00 and the exercise price of such stock option. The Merger is subject to the approval of Closures
stockholders. In addition, the Merger is subject to clearance under the Hart-Scott-Rodino Antitrust Improvements Act, as well as other customary closing conditions. The Merger is currently expected to close in the second quarter of 2005.



ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS.



None.



ITEM 14. PRINCIPAL ACCOUNTANT FEES AND SERVICES.



The following table shows the fees that we incurred for audit and other services provided by PricewaterhouseCoopers LLP, our independent
auditors, for the years ended December 31, 2004 and 2003:



|                       |  |      |         |      |   |        
|---------------------- |  | ---- | ------- | ---- | - | -------
|                       |  | 2004 |         | 2003
|Audit fees             |  | $    | 179,493 |      | $ | 85,000 
|Audit related fees (1) |  |      | 8,900   |      |   |       
|Tax fees (1)           |  |      | 28,037  |      |   | 22,500 
|All other fees         |  |      |        |      |   |       
|                       |  |      |         |      |   |        
|Total                  |  | $    | 216,430 |      | $ | 107,500

---

|(1) | Includes only those amounts that were billed during the fiscal year.
|--- | --------------------------------------------------------------------



10



---

The Audit Committee reviews and approves the annual audit fee directly with PricewaterhouseCoopers LLP. The Audit
Committee has established a policy requiring its pre-approval of all auditing services and permitted non-audit services (including the fees and terms thereof) to be performed for Closure by its independent auditor, subject to the de minimus
exceptions for non-audit services described in Section 10A(i)(1)(B) of the Exchange Act, which are approved by the Audit Committee prior to the completion of the audit. The Audit Committee may form and delegate authority to subcommittees consisting
of one or more members when appropriate, including the authority to grant preapprovals of audit and permitted non-audit services, provided that decisions of such subcommittee to grant preapprovals shall be presented to the full Audit Committee at
its next scheduled meeting. All fees incurred relating to 2004 were approved by the Audit Committee.



PART IV



ITEM 15. EXHIBITS AND FINANCIAL STATEMENT SCHEDULES.



|(a) | 1. Financial Statements.
|--- | ------------------------



The financial statements were filed as part of the initial Form 10-K filed by Closure Medical Corporation with the Securities and Exchange Commission on
March 16, 2005.



2. Financial Statement Schedules.



All financial statement schedules have been omitted because
they are not applicable, or not required, or the information is shown in the financial statements or notes thereto.



3. Exhibits. (See (b) below)



|(b) | Exhibits.
|--- | ---------



The following is a list of exhibits filed as part of this Annual Report. Where so indicated by footnote, exhibits which were previously filed are
incorporated by reference. For exhibits incorporated by reference, the location of the exhibit in the previous filing is indicated in parentheses.



|              |  |                                                                                                                                             
|------------- |  | --------------------------------------------------------------------------------------------------------------------------------------------
|ExhibitNumber |  | Description                                                                                                                                 
|2.1           |  | Agreement and Plan of Merger, dated as of March 3, 2005, among Johnson & Johnson, Holden Merger Sub, Inc. and the Company (Exhibit 2.1) (16)
|              | 
|3.1           |  | Restated Certificate of Incorporation (Exhibit 3.1)(1)                                                                                      
|              | 
|3.2           |  | Amendment to Restated Certificate of Incorporation (Exhibit 3.2)(2)                                                                         
|              | 
|3.3           |  | By-Laws (Exhibit 3.2)(1)                                                                                                                    
|              | 
|10.1         |  | Supply and Distribution Rights Agreement, dated as of March 20, 1996, between Ethicon, Inc. and the Company (Exhibit 10.8)(1)               
|              | 
|10.2         |  | Amended and Restated 1996 Equity Compensation Plan of the Company (Exhibit 10.1) (7)                                                        
|              | 
|10.3         |  | Employment Agreement, dated as of May 31, 1996, between Robert V. Toni and the Company (Exhibit 10.10)(1)                                   
|              | 
|10.4         |  | Employment Agreement, dated as of May 31, 1996, between Jeffrey G. Clark and the Company (Exhibit 10.12)(1)                                 
|              | 
|10.5         |  | Employment Agreement, dated as of May 31, 1996, between Joe B. Barefoot and the Company (Exhibit 10.13)(1)                                  
|              | 
|10.6          |  | Lease, dated February 14, 1997, between AP Southeast Portfolio Partners, L.P. and the Company (Exhibit 10.19)(2)                            
|              | 
|10.7         |  | Employment Agreement, dated as of June 9, 1997, between William M. Cotter and the Company (Exhibit 10.19)(3)                                





11



---

|              |  |                                                                                                                                                                                                                                                  
|------------- |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|ExhibitNumber |  | Description                                                                                                                                                                                                                                      
|10.8         |  | Employment Agreement, dated as of January 1, 1998, between Anthony J. Sherbondy and the Company (Exhibit 10.20)(3)                                                                                                                               
|              | 
|10.9          |  | Amendment, dated August 15, 1997, to Lease, dated February 14, 1997, between AP Southeast Portfolio Partners, L.P. and the Company (Exhibit 10.22)(3)                                                                                            
|              | 
|10.10        |  | 1999 Employee Stock Purchase Plan of the Company (Exhibit 10.1)(4)                                                                                                                                                                               
|              | 
|10.11        |  | Distribution, Supply and Development Agreement, dated as of December 21, 2000, between Colgate Oral Pharmaceuticals, Inc. and the Company (Exhibit 10.23) (8)                                                                                    
|              | 
|10.12        |  | Licensing, Distribution and Supply Agreement between Johnson & Johnson Consumer Products Company and the Company dated as of May 23, 2001 (Exhibit 10.1)(5)                                                                                      
|              | 
|10.13        |  | Amendment, dated September 15, 1998, to Supply and Distribution Rights Agreement, dated as of March 20, 1996, between Ethicon, Inc. and the Company (Exhibit 10.25) (9)                                                                          
|              | 
|10.14        |  | Amendment, dated September 30, 1998, to Supply and Distribution Rights Agreement, dated as of March 20, 1996, between Ethicon, Inc. and the Company (Exhibit 10.26) (9)                                                                          
|              | 
|10.15        |  | Amendment, dated November 6, 2001, to Supply and Distribution Rights Agreement, dated as of March 20, 1996, between Ethicon, Inc. and the Company (Exhibit 10.27) (9)                                                                            
|              | 
|10.16         |  | Rights Agreement, dated as of July 30, 2001 between the Company and American Stock Transfer & Trust Company, as Rights Agent (Exhibit 4)(6)                                                                                                      
|              | 
|10.17        |  | Employment Agreement, dated as of July 9, 2001, between Jerry Y. Jonn and the Company (Exhibit 10.29) (9)                                                                                                                                        
|              | 
|10.18        |  | Amendment to Employment Agreement, dated as of March, 27, 2002, between Robert V. Toni and the Company (Exhibit 10.30) (9)                                                                                                                       
|              | 
|10.19        |  | Employment Agreement, dated as of August 29, 2002, between Daniel A. Pelak and the Company (Exhibit 10.1) (10)                                                                                                                                   
|              | 
|10.20        |  | Defense Agreement, dated as of August 29, 2002, between Daniel A. Pelak and the Company (Exhibit 10.2) (10)                                                                                                                                      
|              | 
|10.21        |  | Amended and Restated Employment Agreement, dated as of February 13, 2003, between Anthony J. Sherbondy and the Company (Exhibit 10.34) (11)                                                                                                      
|              | 
|10.22        |  | Employment Agreement, dated as of March 3, 2003, between James F. Buck and the Company (Exhibit 10.1) (12)                                                                                                                                       
|              | 
|10.23         |  | Amendment, dated May 12, 2003, to Lease, dated February 14, 1997, between AP Southeast Portfolio Partners, L.P. and the Company (Exhibit 10.1) (13)                                                                                              
|              | 
|10.24        |  | Employment Agreement, dated as of December 4, 2003, between Bruce J. Krattenmaker and the Company (Exhibit 10.24) (14)                                                                                                                           
|              | 
|10.25        |  | Employment Agreement, dated as of December 19, 2003, between Michael J. Hoban and the Company (Exhibit 10.25) (14)                                                                                                                               
|              | 
|10.26        |  | Employment Agreement, dated as of December 19, 2003, between Gabriel N. Szabo and the Company (Exhibit 10.26) (14)                                                                                                                               
|              | 
|10.27        |  | Amended and Restated Employment Agreement, dated as of January 12, 2004, between Jeffrey G. Clark and the Company (Exhibit 10.27) (14)                                                                                                           
|              | 
|10.28        |  | Employment Agreement, dated as of December 18, 2003, between Benny Ward and the Company (Exhibit 10.28) (14)                                                                                                                                     
|              | 
|10.29        |  | Employment Agreement, dated as of March 30, 1998, between Debra L. Pawl and the Company (Exhibit 10.29) (14)                                                                                                                                     
|              | 
|10.30         |  | Fourth Amendment to Supply and Distribution Agreement, effective as of December 19, 2003, by and between Ethicon, Inc. and Closure Medical Corporation (Exhibit 10.1) (15)                                                                       
|              | 
|10.31        |  | Separation of Employment and General Release Agreement, dated as of November 18, 2004, between Debra L. Pawl and the Company (Exhibit 10.31) (17)                                                                                                
|              | 
|10.32         |  | Form of Indemnification Agreement between the Company and each of the individuals listed on the schedule thereto, which plans are identical in all material respects (Exhibit 10.1)
(16)                                                         
|              | 
|10.33        |  | Form of Letter Agreement among Johnson & Johnson, the Company and each of the individuals listed on the schedule thereto, which letter agreements are identical in all material respects
except as indicated in such schedule (Exhibit 10.3) (16)
|              | 
|10.34        |  | Form of Letter Agreement among Johnson & Johnson, the Company and each of the individuals listed on the schedule thereto, which letter agreements are identical in all material respects
except as indicated in such schedule (Exhibit 10.4) (16)





12



---

|              |  |                                                                                                                                              
|------------- |  | ---------------------------------------------------------------------------------------------------------------------------------------------
|ExhibitNumber |  | Description                                                                                                                                  
|10.35         |  | Amendment to Rights Agreement, dated as of March 3, 2005, between the Company and American Stock Transfer & Trust Company (Exhibit 10.5) (16)
|              | 
|23.1          |  | Consent of PricewaterhouseCoopers LLP (17)                                                                                                   
|              | 
|31.1*         |  | Certification of Chief Executive Officer                                                                                                     
|              | 
|31.2*         |  | Certification of Chief Financial Officer                                                                                                     
|              | 
|32.1          |  | Certification of Chief Executive Officer pursuant to 18 U.S.C Section 1350 (17)                                                              
|              | 
|32.2          |  | Certification of Chief Financial Officer pursuant to 18 U.S.C Section 1350 (17)                                                              

---

|* | Filed herewith.
|- | ---------------

| | Portions of this exhibit were omitted and filed separately with the Secretary of the Securities and Exchange Commission (the Commission) pursuant to an order of the
Commission granting the Companys application for confidential treatment filed pursuant to Rule 406 under the Securities Act of 1933, as amended.
|- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

| | Compensation plans and arrangements for executives and others.
|- | --------------------------------------------------------------



|(1) | Filed as an exhibit to the Companys Registration Statement on Form S-1 (Registration No. 333-5425) filed with the Commission on June 7, 1996, as amended.
|--- | ----------------------------------------------------------------------------------------------------------------------------------------------------------

|(2) | Filed as an exhibit to the Companys Registration Statement on Form S-1 (Registration No. 333-22981) filed with the Commission on March 7, 1997.
|--- | ------------------------------------------------------------------------------------------------------------------------------------------------

|
|

|(3) | Filed as an exhibit to the Companys Annual Report on Form 10-K for the year ended December 31, 1997.
|--- | -----------------------------------------------------------------------------------------------------

|(3) | Filed as an exhibit to the Companys Registration Statement on Form S-8 (Registration No. 333-72339) filed with the Commission on February 12, 1999.
|--- | ----------------------------------------------------------------------------------------------------------------------------------------------------

|(5) | Filed as an exhibit to the Companys Current Reports on Form 8-K filed June 22, 2001 and November 15, 2001.
|--- | -----------------------------------------------------------------------------------------------------------

|(6) | Filed as an exhibit to the Companys Current Report on Form 8-K filed July 30, 2001.
|--- | ------------------------------------------------------------------------------------

|(7) | Filed as an exhibit to the Companys Registration Statement on Form S-8 (Registration No. 333-118037) filed with the Commission on August 9, 2004.
|--- | --------------------------------------------------------------------------------------------------------------------------------------------------

|(8) | Filed as an exhibit to the Companys Annual Report on Form 10-K for the year ended December 31, 2000.
|--- | -----------------------------------------------------------------------------------------------------

|(9) | Filed as an exhibit to the Companys Annual Report on Form 10-K for the year ended December 31, 2001.
|--- | -----------------------------------------------------------------------------------------------------

|(10) | Filed as an exhibit to the Companys Quarterly Report on Form 10-Q for the period ended September 30, 2002.
|---- | -----------------------------------------------------------------------------------------------------------

|(11) | Filed as an exhibit to the Companys Annual Report on Form 10-K for the year ended December 31, 2002.
|---- | -----------------------------------------------------------------------------------------------------

|(12) | Filed as an exhibit to the Companys Quarterly Report on Form 10-Q for the period ended March 30, 2003.
|---- | -------------------------------------------------------------------------------------------------------

|(13) | Filed as an exhibit to the Companys Quarterly Report on Form 10-Q for the period ended September 30, 2003.
|---- | -----------------------------------------------------------------------------------------------------------

|(14) | Filed as an exhibit to the Companys Annual Report on Form 10-K for the year ended December 31, 2003.
|---- | -----------------------------------------------------------------------------------------------------

|(15) | Filed as an exhibit to the Companys Quarterly Report on Form 10-Q for the period ended March 31, 2004.
|---- | -------------------------------------------------------------------------------------------------------

|(16) | Filed as an exhibit to the Companys Current Report on Form 8-K filed March 8, 2005.
|---- | ------------------------------------------------------------------------------------

|(17) | Incorporated by reference to the Companys Annual Report on Form 10-K for the year ended December 31, 2004, which was filed on March 16, 2005.
|---- | ----------------------------------------------------------------------------------------------------------------------------------------------



|(c) | Financial Statement Schedules.
|--- | ------------------------------



None.



13



---

SIGNATURES



Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by
the undersigned, thereunto duly authorized.



|                     |  |                             |  |                                      
|-------------------- |  | --------------------------- |  | -------------------------------------
|Date: April 29, 2005 |  | CLOSURE MEDICAL CORPORATION
|                     |  |                            
|                     |  | By:                         |  | /s/ Daniel A. Pelak                  
|                     |  |                             |  | DANIEL A. PELAK                      
|                     |  |                             |  | President and Chief Executive Officer



14