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CHAPTER TWO 

TABLE OF CONTENTS 

Section Page 

2.0 INTRODUCTION 1 

2.1 GUIDANCE REGARDING FLEXIBILITY INHERENT TO SW-846 METHODS AND THE 2 

PRECEDENCE OF SW-846 QUALITY CONTROL CRITERIA 

2.2 INFORMATION NECESSARY FOR CHOOSING THE CORRECT PROCEDURE 4 

2.3 CHOOSING PROCEDURES FOR ORGANIC ANALYSES 6 

2.4 CHOOSING PROCEDURES FOR CHARACTERISTIC ANALYSES 11 

2.5 CHOOSING PROCEDURES FOR GROUNDWATER ANALYSES 11

2.6 CHOOSING PROCEDURES FOR INORGANIC ANALYSES 12 

2.7 REFERENCES 12 

TABLE 

2-1 DETERMINATIVE METHODS FOR ORGANIC ANALYTES 13 

2-2 METHOD 8011 (MICROEXTRACTION AND GAS CHROMATOGRAPHY) 30 

2-3 METHOD 8015 (GC/FID) - NONHALOGENATED VOLATILES 30 

2-4 METHOD 8021 (GC, PHOTOIONIZATION AND ELECTROLYTIC CONDUCTIVITY 31 

DETECTORS) - AROMATIC AND HALOGENATED VOLATILES 

2-5 METHODS 8031 AND 8033 (GC WITH NITROGEN-PHOSPHORUS DETECTION) 32 

AND METHOD 8032 (GC WITH ELECTRON CAPTURE DETECTION) 

2-6 METHOD 8041 (GC) - PHENOLS 32 

2-7 METHOD 8061 (GC/ECD) - PHTHALATE ESTERS 33 

2-8 METHOD 8070 (GC) - NITROSAMINES 33 

2-9 METHOD 8081 (GC) - ORGANOCHLORINE PESTICIDES- 34 

2-10 METHOD 8082 (GC) - POLYCHLORINATED BIPHENYLS 35 

2-11 METHOD 8085 (GC/AED) - PESTICIDES 36 

2-12 METHOD 8091 (GC) - NITROAROMATICS AND CYCLIC KETONES 38 

2-13 METHOD 8095 (GC) - EXPLOSIVES 38 

2-14 METHOD 8100 - POLYNUCLEAR AROMATIC HYDROCARBONS 39 

2-15 METHOD 8111 (GC) - HALOETHERS 39 

2-16 METHOD 8121 (GC) - CHLORINATED HYDROCARBONS 40

2-17 METHOD 8131 (GC) - ANILINE AND SELECTED DERIVATIVES 40 

2-18 METHOD 8141 (GC) - ORGANOPHOSPHORUS COMPOUNDS 41 

2-19 METHOD 8151 (GC USING METHYLATION OR PENTAFLUOROBENZYLATION 42 

DERIVATIZATION) - CHLORINATED HERBICIDES 

2-20 METHOD 8260 (GC/MS) - VOLATILE ORGANIC COMPOUNDS 43 

2-21 METHOD 8261 (VD/GC/MS) - VOLATILE ORGANIC COMPOUNDS 45 

 
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Table 

2-22 

CHAPTER TWO 

TABLE OF CONTENTS (continued) 

METHOD 8270 (GC/MS) - SEMIVOLATILE ORGANIC COMPOUNDSPage 

46 

2-23 METHOD 8275 (TE/GC/MS) - SEMIVOLATILE ORGANIC COMPOUNDS 51 

2-23A METHOD 8276 (GC-NICI/MS) - TOXAPHENE AND TOXAPHENE CONGENERS 52 

2-24 METHODS 8280 (HRGC/LRMS) AND 8290 (HRGC/HRMS) - POLYCHLORINATED 52 

DIBENZO-p-DIOXINS (PCDDs) AND POLYCHLORINATED DIBENZOFURANS 

 (PCDFs) 

2-25 METHOD 8310 (HPLC) - POLYNUCLEAR AROMATIC HYDROCARBONS 53 

2-26 METHOD 8315 - CARBONYL COMPOUNDS 53 

2-27 METHOD 8316 (HPLC) 54 

2-28 METHOD 8318 (HPLC) - N-METHYLCARBAMATES 54 

2-29 METHOD 8321 (HPLC/TS/MS) - NONVOLATILE ORGANIC COMPOUNDS 55 

2-29A METHOD 8323 - ORGANOTINS BY MICRO-LIQUID CHROMATOGRAPHY- 57 

 ELECTROSPRAY ION TRAP MASS SPECTROMETRY 

2-30 METHOD 8325 (HPLC/PB/MS) - NONVOLATILE ORGANIC COMPOUNDS 57 

2-31 METHOD 8330 (HPLC) - NITROAROMATICS AND NITRAMINES 57 

2-32 METHOD 8331 (HPLC) 58 

2-33 METHOD 8332 (HPLC) 58 

2-34 METHOD 8410 - SEMIVOLATILE ORGANIC COMPOUNDS 58 

2-35 METHOD 8430 (GC/FT-IR) - BIS(2-CHLOROETHYL) ETHER AND ITS HYDROLYSIS 59 

 PRODUCTS 

2-35A METHOD 8440 - TOTAL RECOVERABLE PETROLEUM HYDROCARBONS BY 59 

 INFRARED SPECTROPHOTOMETRY 

2-36 METHOD 8510 (COLORIMETRIC SCREENING) - RDX AND HMX 60 

2-36A METHOD 8520 - CONTINUOUS MEASUREMENT OF FORMALDEHYDE IN AMBIENT 60 

 AIR 

2-37 METHOD 8535 (COLORIMETRIC SCREENING) - VOLATILE ORGANIC HALIDES 60 

2-38 METHOD 8540 (UV-INDUCED COLORIMETRY) - PENTACHLOROPHENOL 60 

2-39 DETERMINATIVE METHODS FOR INORGANIC ANALYTES 61 

2-40A RECOMMENDED SAMPLE CONTAINERS, PRESERVATION TECHNIQUES, AND 63 

 HOLDING TIMES FOR ORGANIC CHEMICALS 

2-40B RECOMMENDED CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING 67 

 TIMES FOR INORGANIC AND OTHER ANALYTES IN AQUEOUS MATRICES 

2-41 PREPARATION METHODS FOR ORGANIC ANALYTES 69 

2-42 CLEANUP METHODS FOR ORGANIC ANALYTE EXTRACTS 73 

2-43 DETERMINATIVE METHODS ORGANIC ANALYTES 74 

2-44 PREPARATION METHODS FOR INORGANIC ANALYSES 75 

2-45 USE OF LEACHING, EXTRACTION AND DIGESTION METHODS FOR INORGANIC 76 

 ANALYSIS (IN ORDER OF INCREASING STRENGTH) 

2-46 SCREENING METHODS FOR ORGANIC ANALYTES 78 

 
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FIGURE 

2-1 ORGANIC ANALYSIS OPTIONS FOR SOLID AND LIQUID MATRICES 79 

2-2 SCHEMATIC OF SEQUENCE TO DETERMINE IF A WASTE IS HAZARDOUS BY 80 

 CHARACTERISTIC 

2-3A RECOMMENDED SW-846 METHODS FOR ANALYSIS OF EP LEACHATES 82 

2-3B RECOMMENDED SW-846 METHODS FOR ANALYSIS OF TCLP LEACHATES 83 

2-4A GROUNDWATER ANALYSIS - ORGANIC ANALYTES 84 

2-4B GROUNDWATER ANALYSIS - INDICATOR ANALYTES 85 

2-4C GROUNDWATER ANALYSIS - INORGANIC ANALYTES 86 

Appendix A SUMMARY OF UPDATES/CHANGES IN CHAPTER 2 87 
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CHAPTER TWO 

CHOOSING THE CORRECT PROCEDURE 

 SW-846 is not intended to be an analytical training manual. Therefore, method 

procedures are written based on the assumption that they will be performed by analysts who are 

formally trained in at least the basic principles of chemical analysis and in the use of the subject 

technology. 

 In addition, SW-846 methods, with the exception of required method use for the analysis 

of method-defined parameters, are intended to be guidance methods containing general 

information on how to perform an analytical procedure or technique which a laboratory can use 

as a basic starting point for generating its own detailed Standard Operating Procedure (SOP), 

either for its own general use or for a specific project application. The performance data 

included in these methods are for guidance purposes only, and are not intended to be and must 

not be used as absolute quality control (QC) acceptance criteria for the purposes of laboratory 

accreditation. 

2.0 INTRODUCTION 

 The purpose of this chapter is to aid the analyst in choosing the appropriate methods for 

sample analyses, based upon the sample matrix and the analytes to be determined. The 

ultimate responsibility for producing reliable analytical results lies with the entity subject to the 

regulation. Therefore, members of the regulated community are advised to refer to this chapter 

and to consult with knowledgeable laboratory personnel when choosing the most appropriate 

suite of analytical methods. In addition, analysts and data users are advised that, except where 

explicitly specified in a regulation, the use of SW-846 methods is not mandatory in response to 

Federal testing requirements. 

 SW-846 analytical methods are written as quantitative analytical methods, and specific 

methods may be used to demonstrate that a waste does not contain analytes of concern that 

cause it to be managed as a hazardous waste. SW-846 methods typically contain relatively 

stringent recommended QC criteria appropriate to many levels of analyses, including trace. 

However, if a particular application does not require data of this quality, less stringent QC 

criteria may and should be used. 

 The choice of the appropriate sequence of analytical methods depends on the information 

sought and on the experience of the analyst. Appropriate selection is confirmed by the usability 

of data (i.e., adequate for its intended use). The use of the recommended procedures, whether 

they are approved or mandatory, does not release the analyst from demonstrating the correct 

execution of the method. 

 Sec. 2.1 provides guidance regarding the analytical flexibility inherent to SW-846 methods 

and the precedence of various QC criteria. Sec. 2.2 reviews the information required to choose 

the correct combination of methods for an analytical procedure. Sec. 2.3 provides useful 

information on implementing the method selection guidance for organic analyses. Sec. 2.4 

provides guidance on choosing procedures for characteristic analyses. Sec. 2.5 provides 

guidance on the determination of analytes in groundwater. Finally, Sec. 2.6 provides 
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information regarding choosing procedures for inorganic analyte analyses. Tables and figures 

referenced in this chapter are sequentially located after the last page of chapter text. 

2.1 GUIDANCE REGARDING FLEXIBILITY INHERENT TO SW-846 METHODS AND THE 

PRECEDENCE OF SW-846 QUALITY CONTROL CRITERIA 

 The specific products and instrument settings cited in SW-846 methods represent those 

products and settings used during method development or subsequently evaluated by the 

Agency for use in the method. Glassware, reagents, supplies, equipment and settings other 

than those listed in this manual may be employed, provided that method performance 

appropriate for the intended application has been documented. Such performance includes 

consideration of precision, accuracy (or bias), recovery, representativeness, comparability, and 

sensitivity (quantitation or reporting limits, now referred to as lower limit of quantitation (LLOQ)) 

relative to the data quality objectives (DQOs) for the intended use of the analytical results. In 

response to this inherent flexibility, if an alternative analytical procedure is employed, then EPA 

expects the laboratory to demonstrate and document that the procedure is capable of providing 

appropriate performance for its intended application. This demonstration must not be performed 

after the fact, but as part of the laboratory’s initial demonstration of proficiency with the method. 

The documentation should be in writing, maintained in the laboratory, and available for 

inspection upon request by authorized representatives of the appropriate regulatory authorities. 

The documentation should include the performance data as well as a detailed description of the 

procedural steps as performed (i.e., a written standard operating procedure). 

 Given this allowance for flexibility, EPA wishes to emphasize that this manual also 

contains procedures for "method-defined parameters," where the analytical result is wholly 

dependent on the process used to make the measurement. Examples include: the use of the 

toxicity characteristic leaching procedure (TCLP) to prepare a leachate, and the flash point, pH, 

paint filter liquids, and corrosivity tests. In these instances, changes to the specific methods 

may change the end result and incorrectly identify a waste as nonhazardous. Therefore, when 

the measurement of such method-defined parameters is required by regulation, those methods 

are not subject to the flexibility afforded in other methods. 

 Analysts and data users are advised that even for those analytes that are not methoddefined, different procedures may produce some difference in results. Common examples 

include the differences in recoveries of phenolic compounds extracted from water by separatory 

funnel (Method 3510) and continuous liquid-liquid (Method 3520) extraction techniques, 

differences in recoveries of many compounds between Soxhlet (Method 3540) and ultrasonic 

(Method 3550) extraction techniques, and differences resulting from the choice of acid digestion 

of metals (Method 3050) or microwave digestion (Method 3051). Where practical, the Agency 

has included guidance in the individual methods regarding known potential problems, and 

analysts are advised to review this information carefully in choosing or modifying analytical 

procedures. Chapter One describes a variety of QC procedures that may be used to evaluate 

the quality of the analytical results. Additional QC procedures may be described in the 

individual methods. The results of these QC procedures should be used by the analyst to 

evaluate if the analytical procedures and/or any modifications are appropriate to generate data 

of the quality necessary to satisfy the data quality needs of the intended application. 

 The performance data included in the SW-846 methods are not intended to be used as 

absolute QC acceptance criteria for method performance. The data are intended to be 

guidance, by providing typical method performance in typical matrices, to assist the analyst in 

selection of the appropriate method for the intended application. In addition, it is the 
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responsibility of the laboratory to establish actual operating parameters and in-house QC 

acceptance criteria, based on its own laboratory SOPs and in-house QC program, to 

demonstrate appropriate performance of the methods used in that laboratory for the RCRA 

analytical applications for which they are intended. 

 

 The regulated community is further advised that the methods here or from other sources 

need only be used for those specific analytes of concern that are subject to regulation or other 

monitoring requirements. The fact that a method provides a long list of analytes does not mean 

that each of those analytes is subject to any or all regulations, or that all of those analytes must 

be analyzed each time the method is employed, or that all of the analytes can be analyzed 

using a single sample preparation procedure. It is EPA’s intention that the target analyte list for 

any procedure includes those analytes necessary to meet the DQOs of the project (i.e., those 

analytes subject to monitoring requirements and set out in a RCRA permit or other applicable 

regulation, plus those analytes used in the methods for QC purposes, such as surrogates, 

internal standards, system performance check compounds, etc.). Additional analytes, not 

included on the analyte list of a particular method(s) but needed for a specific project, may be 

analyzed by that particular method(s), if appropriate performance can be demonstrated for 

those analytes in the matrices of concern at the levels of concern. 

 2.1.1 Trace analysis vs. macroanalysis 

 Through the choice of sample size and concentration procedures, the methods presented 

in SW-846 were designed to address the problem of "trace" analyses (<1000 ppm), and have 

been developed for an optimized working range. These methods are also applicable to "minor" 

(1000 ppm - 10,000 ppm) and "major" (>10,000 ppm) analyses, as well, through use of 

appropriate sample preparation techniques that result in analyte concentrations within that 

optimized range. Such sample preparation techniques include: 

 1. Adjustment of size of sample prepared for analysis (for homogeneous samples) 

2. Adjustment of injection volumes 

3. Dilution or concentration of sample 

4. Eelimination of concentration steps prescribed for "trace" analyses 

5. Direct injection (of samples to be analyzed for volatile constituents) 

 The performance data presented in each of these methods were generated from "trace" 

analyses, and may not be applicable to "minor" and "major" analyses. Generally, extraction 

efficiency improves as concentration increases. 

CAUTION: Great care should be taken when performing trace analyses after the analysis of 

concentrated samples, given the possibility of contamination. 

 2.1.2 Choice of apparatus and preparation of reagents 

 Since many types and sizes of glassware and supplies are commercially available, and 

since it is possible to prepare reagents and standards in many different ways, the apparatus, 

reagents, and volumes included in these methods may be replaced by any similar types as long 

as this substitution does not affect the overall quality of the analyses. 

 2.1.3 Quality control criteria precedence 
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 Chapter One contains general QC guidance for analyses using SW-846 methods. QC 

guidance specific to a given analytical technique (e.g., extraction, cleanup, sample introduction, 

or analysis) may be found in Methods 3500, 3600, 5000, 7000, and 8000. Method-specific QC 

criteria may be found in Sec. 8.0 of most older individual methods, in Sec. 9.0 of newer 

methods, or in Sec. 11.0 of some air sampling methods. When inconsistencies exist between 

the information in these locations, method-specific QC criteria take precedence over both 

technique-specific criteria and those criteria given in Chapter One, and technique-specific QC 

criteria take precedence over the criteria in Chapter One. 

2.2 INFORMATION NECESSARY FOR CHOOSING THE CORRECT PROCEDURE 

 In order to choose the correct combination of methods to comprise the appropriate 

analytical procedure, some basic information is necessary. This includes information on: 

1. The physical state of the sample 

2. The analytes of interest 

3. The analytical sensitivity needed 

4. The analytical objective 

5. Whether the purpose is quantitation or monitoring 

6. What sample containers and preservation will be used and what holding times may 

apply 

 2.2.1 Physical state(s) of sample 

 The phase characteristics of the sample must be known. There are several general 

categories of phases into which the sample may be categorized, including: 

 Aqueous Oil or other Organic Liquid 

 Sludge Multiphase Sample 

 Solid Groundwater 

 Stack Sampling –Volatile Organics Sampling Train (VOST) Condensate 

 TCLP or Extraction Procedure (EP) Extract 

 

 There may be a substantial degree of overlap between the phases listed above and it may 

be useful to further divide these phases in certain instances. A multiphase sample may be a 

combination of aqueous, organic liquid, sludge, and/or solid phases, and generally must 

undergo a phase separation as the first step in the analytical procedure. 

 2.2.2 Analytes of interest 

 Analytes may be divided into various classes, based on the determinative methods used 

to identify and quantify them. The most basic differentiation is between organic (e.g., carboncontaining) analytes and inorganic (e.g., metals and anions) analytes. 

 Table 2-1 is an alphabetical list of analytes cited within the SW-846 organic determinative 

methods (excludes immunoassay and other screening methods). These analytes have been 

evaluated by those methods. The methods may also be applicable to other analytes that are 

similar to those listed. Tables 2-2 through 2-38 list the analytes for each organic determinative 

method. Table 2-39 indicates which methods are applicable to inorganic analytes. 
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NOTE: Analysts should review the discussion in Sec. 2.1 of this chapter with regard to the 

presence of an analyte in a method versus the need for its analysis for a given project. 

 

 2.2.3 Sensitivity 

 Some regulations may require a specific sensitivity or quantitation limit (LLOQ) for an 

analysis, as in the determination of analytes for the Toxicity Characteristic (TC). Drinking water 

quantitation limits, for those specific organic and metallic analytes covered by the National 

Primary Drinking Water Regulations, are desired in the analysis of groundwater. 

 

2.2.4 Analytical objective 

 Knowledge of the analytical objective is essential in the choice of sample preparation 

procedures and in the selection of a determinative method. This is especially true when the 

sample has more than one phase. Knowledge of the analytical objective may not be possible or 

desirable at all management levels, but that information should be included in the project 

planning document and transmitted to the analytical laboratory management to ensure that the 

correct techniques are used during the analytical effort. Screening methods or composite 

sampling may be highly beneficial for some applications in order to generate a broader view of 

contaminant distribution than may be possible with a more precise and more costly method. 

Table 2-46 identifies some screening methods appropriate for different classes of organic 

chemicals in certain matrices. 

 2.2.5 Quantitation or monitoring 

 The strategy for quantitation of compounds in environmental or process samples may be 

contrasted with the strategy for collecting monitoring data. When there is little information 

available about the composition of the sample source (e.g., a well or process stream), mass 

spectral identification of organic analytes leads to fewer false positive results. Thus, the most 

practical form of quantitation for organic analytes is often mass spectral identification. However, 

where the sensitivity requirements exceed those that can be achieved using mass spectral 

methods (e.g., gas chromatography/mass spectrometry (GC/MS) or high performance liquid 

chromatography (HPLC)/MS), it may be necessary to employ a more sensitive quantitation 

method (e.g., electron capture). In these instances, the risk of false positive results may be 

minimized by confirming the results through a second analysis with a dissimilar detector or 

chromatographic column. Thus, the choice of technique for organic analytes may be governed 

by the sensitivity requirements and potential interferants. 

 Similarly, the choice of technique for metals may be governed by the sensitivity 

requirements and potential interferants. 

 In contrast, monitoring samples are analyzed to confirm existing and ongoing conditions, 

tracking the presence or absence of known constituents in an environmental or process matrix. 

In well-defined matrices and under stable analytical conditions, less compound-specific 

quantitation modes may be used, as the risk of false positive results is less. 

 2.2.6 Sample preservation and holding times 

 Table 2-40 provides information regarding recommended sample preservation techniques, 

sample holding times, and other information. Similar information may be found in Table 3-1 of 

Chapter Three (inorganic analytes) and Table 4-1 of Chapter Four (organic analytes). Samples 
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need to be extracted and analyzed within the recommended holding times for the results to be 

considered reflective of native concentrations as collected. Analytical data generated outside of 

the recommended holding times should typically be considered as minimum values only. Such 

data may be used to demonstrate that a waste is hazardous where it shows the concentration of 

a constituent to be above the regulatory threshold, but cannot be used to demonstrate that a 

waste is not hazardous. However, regarding the information in Table 2-40, a longer holding 

time may be appropriate if it can be demonstrated that reported concentrations are not 

adversely affected from preservation, storage and analyses performed outside the 

recommended holding times. 

2.3 CHOOSING PROCEDURES FOR ORGANIC ANALYSES 

 Table 2-1 summarizes the organic analysis options available in SW-846. 

2.3.1 Extraction and sample preparation procedures for organic analytes 

 SW-846 methods for preparing samples for organic analytes are shown in Table 2-41. 

Method 3500 and associated methods should be consulted for further details on preparing the 

sample for analysis. 

 2.3.1.1 Aqueous samples 

 Methods 3510, 3520, and 3535 may be used for extraction of the semivolatile 

organic compounds (SVOCs) from aqueous samples. The choice of a preparative method 

depends on the sample. Method 3510, a separatory funnel liquid-liquid extraction 

technique, is appropriate for samples which will not form a persistent emulsion interface 

between the sample and the extraction solvent. The formation of an emulsion that cannot 

be broken up by mechanical techniques will prevent proper extraction of the sample. 

Method 3520, a continuous liquid-liquid extraction technique, may be used for any 

aqueous sample and will minimize emulsion formation. 

 Method 3535 is solid-phase extraction technique that has been tested for 

organochlorine pesticides, phthalate esters, polychlorinated biphenyls (PCBs), 

organophosphorus pesticides, nitroaromatics and nitramines, and some explosive 

compounds, and may be applicable to other semivolatile and extractable compounds as 

well. The aqueous sample is passed through a solid sorbent material which traps the 

analytes. They are then eluted from the solid-phase sorbent with a small volume of 

organic solvent. This technique may be used to minimize the volumes of organic solvents 

that are employed, but may not be appropriate for aqueous samples with high suspended 

solids contents. 

 2.3.1.1.1 Acidic extraction of phenols and acid analytes 

 The solvent extract obtained by performing Method 3510, 3520, or 3535 

at a pH less than or equal to 2 will contain the phenols and acid/neutral extractable 

organics of interest, and may contain some mildly basic compounds. The 

particular pH extraction conditions needs to be defined during the project planning 

process based on the desired target analytes and performance goals. 

 2.3.1.1.2 Basic or neutral extraction of semivolatile analytes 
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 The solvent extract obtained by performing Method 3510, 3520, or 3535 

at a basic pH will contain the organic bases of interest, if acid extraction is 

performed first. It will also contain the neutral compounds of interest, if acid 

extraction is not performed. Refer to Table 1 in the extraction methods (3510 

and/or 3520) for guidance on the requirements for pH adjustment prior to extraction 

and analysis. 

 2.3.1.2 Solid samples 

 Soxhlet extraction (Methods 3540, 3541 and 3542), pressurized fluid extraction 

(Method 3545), microwave extraction (Method 3546) and ultrasonic extraction (Method 

3550) may be used with solid samples. Consolidated samples should be ground finely 

enough to pass through a 1-mm sieve. In limited applications, waste dilution (Methods 

3580 and 3585) may be used if the entire sample is soluble in the specified solvent. 

 Methods 3540, 3541, 3542, 3545, 3546 and 3550 are neutral-pH extraction 

techniques and therefore, depending on the analysis requirements, acid-base partition 

cleanup (Method 3650) may be necessary. Method 3650 will only be needed if 

chromatographic interferences are severe enough to prevent quantitation of the analytes 

of interest. This separation will be most important if a gas chromatography (GC) method is 

chosen for analysis of the sample. If GC/MS is used, the ion selectivity of the technique 

may compensate for chromatographic interferences. 

 There are three extraction procedures for solid samples that employ supercritical 

fluid extraction (SFE). Method 3560 is a technique for the extraction of petroleum 

hydrocarbons from various solid matrices using carbon dioxide at elevated temperature 

and pressure. Method 3561 may be used to selectively extract polynuclear aromatic 

hydrocarbons (PAHs) from solid matrices using supercritical carbon dioxide and 

appropriate modifiers, based on the determinative procedure to be used. Method 3562 

may be used to selectively extract organochlorine pesticides or PCBs from solid matrices 

using supercritical carbon dioxide. 

 2.3.1.3 Oils and organic liquids 

 Method 3580, waste dilution, may be used to prepare oils and organic liquid 

samples for analysis of semivolatile and extractable organic analytes by GC or GC/MS. 

Method 3585 may be employed for the preparation of these matrices for volatiles analysis 

by GC or GC/MS. To avoid overloading the analytical detection system, care must be 

exercised to ensure that proper dilutions are made. Methods 3580 and 3585 give 

guidance on performing waste dilutions. 

 To remove interferences for semivolatiles and extractables, Method 3611 (alumina 

cleanup) may be performed on an oil sample directly, without prior sample preparation. 

 Method 3650 is the only other preparative procedure for oils and other organic 

liquids. This procedure is a back extraction into an aqueous phase. It is generally 

introduced as a cleanup procedure for extracts rather than as a preparative procedure. 

Oils generally have a high concentration of semivolatile compounds and, therefore, 

preparation by Method 3650 should be done on a relatively small aliquot of the sample. 

Generally, extraction of 1 mL of oil will be sufficient to obtain a saturated aqueous phase 

and avoid emulsions. 
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 NOTE: The use of traditional extraction techniques (i.e., 3510, 3520, 3535, 3540, 3541, 

3545, 3546, and 3550), is neither suitable nor recommended for use in these 

matrices due to a high potential for hydrocarbon interferences and decreased 

determinative method sensitivity (i.e., poor analytical performance). 

 2.3.1.4 Sludge samples 

 Determining the appropriate methods for analysis of sludges is complicated 

because of the lack of precise definitions of sludges with respect to the relative percent of 

liquid and solid components. There is no set ratio of liquid to solid that enables the analyst 

to determine which of the three extraction methods cited is the most appropriate. Sludges 

may be classified into three categories: liquid sludges, solid sludges, and emulsions, but 

with appreciable overlap. 

 If the sample is an organic sludge (solid material and organic liquid, as opposed to 

an aqueous sludge), the sample should be handled as a multiphase sample. 

 

2.3.1.4.1 Liquid sludges 

 Method 3510 or Method 3520 may be applicable to sludges that behave 

like, and have the consistency of, aqueous liquids. Ultrasonic extraction (Method 

3550) and Soxhlet-type (Method 3540 series) procedures will, most likely, be 

ineffective because of the overwhelming presence of the liquid aqueous phase. 

 2.3.1.4.2 Solid sludges 

 Soxhlet extraction (Methods 3540 and 3541), pressurized fluid extraction 

(Method 3545), microwave extraction (Method 3546), and ultrasonic extraction 

(Method 3550) will be more effective when applied to sludge samples that 

resemble solids. Samples may be dried or centrifuged to form solid materials for 

subsequent determination of semivolatile compounds.

 Using Method 3650, Acid-Base Partition Cleanup, on the extract may be 

necessary, depending on whether chromatographic interferences prevent 

determination of the analytes of interest. 

 2.3.1.4.3 Emulsions 

 Attempts should be made to break up and separate the phases of an 

emulsion. Several techniques are effective in breaking emulsions or separating the 

phases of emulsions, including: 

 1. Freezing/thawing -- Certain emulsions will separate if exposed to 

temperatures below 0 °C. 

 2. Salting out -- Addition of a salt to make the aqueous phase of an emulsion too 

polar to support a less polar phase promotes separation. 

 3. Centrifugation -- Centrifugal force may separate emulsion components by 

density. 
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 4. Addition of water or ethanol -- Emulsion polymers may be destabilized when a 

preponderance of the aqueous phase is added. 

5. Forced filtering through glass wool -- Many emulsions can be broken by 

forcing the emulsion through a pad of Pyrex glass wool in a drying column 

using a slight amount of air pressure (using a rubber bulb usually provides 

sufficient pressure). 

 If techniques for breaking emulsions fail, use Method 3520. If the 

emulsion can be broken, the different phases (aqueous, solid, or organic liquid) 

may then be analyzed separately. 

 2.3.1.5 Multiphase samples 

 Choice of the procedure for separating multiphase samples is highly dependent on 

the objective of the analysis. With a sample in which some of the phases tend to separate 

rapidly, the percent weight or volume of each phase should be calculated and each phase 

should be individually analyzed for the required analytes. 

 

 An alternate approach is to obtain a homogeneous sample and attempt a single 

analysis on the combination of phases. This approach will give no information on the 

abundance of the analytes in the individual phases other than what can be implied by 

solubility. 

 A third alternative is to select phases of interest and to analyze only those selected 

phases. This tactic must be consistent with the sampling/analysis objectives or it will yield 

insufficient information for the time and resources expended. The phases selected should 

be compared with Figure 2-1 and Table 2-41 for further guidance. 

 2.3.2 Cleanup procedures 

 Cleanup procedure selection is determined by the analytes of interest within the extract. 

Each analyte type in Table 2-42, Cleanup Methods for Organic Analyte Extracts, corresponds to 

one or more of the possible determinative methods available in the manual. However, the 

necessity of performing cleanup may also depend upon the matrix from which the extract was 

developed. Cleanup of a sample may be done exactly as instructed in the cleanup method for 

some of the analytes. There are some instances when cleanup using one of the methods may 

only proceed after the procedure is modified to optimize recovery and separation. Several 

cleanup techniques may be possible for each analyte category. The information provided is not 

meant to imply that any or all of these methods must be used for the analysis to be acceptable. 

Extracts with components which interfere with spectral or chromatographic determinations are 

expected to be subjected to cleanup procedures. 

 The analyst, in consultation with the regulator, customer, and other project planning 

participants as necessary, must determine the necessity for cleanup procedures, as there are 

no clear-cut criteria for indicating their use. Method 3600 and associated methods should be 

consulted for further details on extract cleanup. 
SW-846 Update V TWO - 10 Revision 5 

July 2014

 2.3.3 Determinative procedures 

 In Table 2-43, the determinative methods for organic analytes are divided into four 

categories, specifically: GC/MS (this category includes single quadrupole MS, triple quadrupole 

(MS/MS), and time-of-flight instruments); GC with electromagnetic spectrometric (ES) detectors 

(i.e., Fourier Transform infrared (FT-IR) or atomic emission (AES)); specific quantitation 

methods (i.e., GC with specific non-MS detectors); and HPLC, including any HPLC-MS 

methods. This division is intended to help an analyst choose which determinative method will 

apply. Under each analyte column, SW-846 method numbers are indicated, if appropriate, for 

the determination of the analyte. A blank has been left if no chromatographic determinative 

method is available. 

 Generally, the MS procedures are more specific but less sensitive than the appropriate 

gas chromatographic/specific quantitation or ES method. 

 Method 8000 gives a general description of the techniques of GC and HPLC. Method 

8000 should be consulted prior to application of any of the GC or HPLC methods. 

 Method 8081 (organochlorine pesticides), Method 8082 (PCBs), Method 8141 

(organophosphorus pesticides), and Method 8151 (chlorinated herbicides), are preferred over 

GC/MS because of the combination of selectivity and sensitivity of the flame photometric, 

nitrogen-phosphorus, and electron capture detectors. 

 Method 8260 is a GC/MS method for volatile analytes. A variety of sample introduction 

techniques may be used with Method 8260, including Methods 5021, 5030, 5031, 5035, 5041, 

and 3585. A GC with a selective detector is also useful for the determination of volatile organic 

compounds in a monitoring scenario, as described in Sec. 2.2.5. 

 Method 8270 is a GC/MS method for semivolatile analytes. Method 8410 is another GC 

method for semivolatile analytes which uses a FT-IR detector. Method 8085 is a GC method for 

pesticides which uses an AES detector. 

 Table 2-43 lists several GC and HPLC methods that apply to only a small number of 

analytes. Methods 8031 and 8033 are GC methods for acrolein, acrylonitrile, and acetonitrile. 

Methods 8315 and 8316 are HPLC methods for these three analytes. Method 8316 also 

addresses acrylamide, which may be analyzed by Method 8032. Method 8325 is an HPLC 

coupled with particle beam MS for the determination of benzidines and 

nitrogen-containing pesticides in water and wastewater. Method 8520 measures formaldehyde 

in ambient air primarily for non-occupational exposure monitoring. Method 8540 is used for 

field-testing of soil samples for pentachlorophenol (PCP). 

 HPLC methods have been developed for other types of analytes, most notably N-methyl 

carbamates (Method 8318); azo dyes, phenoxy acid herbicides, carbamates, and 

organophosphorus pesticides (Method 8321); PAHs (Method 8310); explosives (Methods 8330, 

8331, and 8332); and some volatile organics (Methods 8315 and 8316). 

 Method 8430 utilizes a FT-IR spectrometer coupled to a gas chromatograph to determine 

bis(2-chloroethyl) ether and its hydrolysis products. The sample is introduced by direct aqueous 

injection. Method 8440 may be employed for the determination of total recoverable petroleum 

hydrocarbons (TRPH) in solid samples by infrared (IR) spectrophotometry. The samples may 

be extracted with supercritical carbon dioxide, using Method 3560. 
SW-846 Update V TWO - 11 Revision 5 

July 2014

2.4 CHOOSING PROCEDURES FOR CHARACTERISTIC ANALYSES

 2.4.1 Figure 2-2 outlines a sequence for determining if a waste exhibits one or more of 

the characteristics of a hazardous waste. 

 2.4.2 SPLP, EP and TCLP extracts 

 The leachate obtained from using either the Synthentic Precipitation Leaching procedure 

(SPLP), EP (Figure 2-3A) or the TCLP (Figure 2-3B) is an aqueous sample, and therefore, 

requires further solvent extraction prior to the analysis of semivolatile compounds. 

 The SPLP or TCLP leachate is solvent extracted with methylene chloride at a pH <2 and 

at a pH >11 by either Method 3510 or 3520. The leachate may also be extracted as received 

for organochlorine pesticides and semivolatiles and at pH <1.0 for phenoxyacid herbicides using 

the solid phase extraction (SPE) disk option in Method 3535. The best recoveries are usually 

obtained using either Method 3520 or Method 3535. 

 The solvent extract obtained by performing either Method 3510 or 3520 at an acidic pH will 

contain the acid/neutral compounds of interest. Refer to the specific determinative method for 

guidance on the pH requirements for extraction prior to analysis. Method 5031 (azeotropic 

distillation) may be used as an effective preparative method for pyridine. 

 Due to the high concentration of acetate in the TCLP extract, it is recommended that 

purge-and-trap be used to introduce the volatile sample into the gas chromatograph. 

 

The SPLP, EP and/or TCLP extracts can also be digested using acids (Method 3010, 3015, or 

3020) and analyzed for metals using a 6000 or 7000 series method (Figures 2-3A and 2-3B). 

2.5 CHOOSING PROCEDURES FOR GROUNDWATER ANALYSES 

 Appropriate analysis schemes for the determination of analytes in groundwater are 

presented in Figures 2-4A, 2-4B, and 2-4C. Quantitation limits (LLOQs) for the inorganic 

analytes should correspond to the drinking water limits, where such limits are available. 

 2.5.1 Special techniques for inorganic analytes 

 All atomic absorption (AA) analyses should employ appropriate background correction 

systems whenever spectral interferences could be present. Several background correction 

techniques are employed in modern AA spectrometers. Matrix modification can complement 

background correction in some cases. Since no approach to interference correction is 

completely effective in all cases, the analyst should attempt to verify the adequacy of correction. 

If the interferant is known (e.g., high concentrations of iron in the determination of selenium), 

accurate analyses of synthetic solutions of the interferant (with and without analyte) could 

establish the efficacy of the background correction. If the nature of the interferant is not 

established, good agreement of analytical results using two substantially different wavelengths 

could substantiate the adequacy of the background correction. 
SW-846 Update V TWO - 12 Revision 5 

July 2014

 To reduce matrix interferences, all graphite furnace atomic absorption (GFAA) analyses 

should be performed using techniques which maximize an isothermal environment within the 

furnace cell. Data indicate that two such techniques, L'vov platform and the delayed 

atomization cuvette (DAC), are equivalent in this respect, and produce high quality results. 

 All GFAA analysis should be carried out using the best matrix modifier for the analysis. 

Some examples of modifiers are listed below. (See also the appropriate methods.) 

Element(s) Modifier(s) 

As and Se Nickel nitrate, palladium 

Pb Phosphoric acid, ammonium phosphate, palladium 

Cd Ammonium phosphate, palladium 

Sb Ammonium nitrate, palladium 

Tl Platinum, palladium 

 Inductively coupled plasma (ICP), AA, and GFAA calibration standards need to match the 

acid composition and strength of the acids contained in the samples. Acid strengths of the 

calibration standards should be stated in the raw data. When using a method which permits the 

use of internal standardization, and the internal standardization option is being used, matrix 

matching is not required. 

2.6 CHOOSING PROCEDURES FOR INORGANIC ANALYSES 

 Methods for preparing different sample matrices for inorganic analyses are shown in Table 

2-44. Guidance regarding the use of leaching and digestive methods for inorganic analysis is 

provided in Table 2-45. 

2.7 REFERENCES 

1. M. J. Barcelona, "TOC Determinations in Ground Water," Ground Water 1984, 22(1), 18-

24. 

2. R. Riggin, et al.; Development and Evaluation of Methods for Total Organic Halide and 

Purgeable Organic Halide in Wastewater; U.S. Environmental Protection Agency; Office of 

Research and Development; Environmental Monitoring and Support Laboratory; ORD 

Publication Offices of Center for Environmental Research Information; Cincinnati, OH, 

1984; EPA-600/4-84-008. 

3. G. McKee, et al.; Determination of Inorganic Anions in Water by Ion Chromatography 

(Technical addition to Methods for Chemical Analysis of Water and Wastewater, EPA 

600/4-79-020); U.S. Environmental Protection Agency; Environmental Monitoring and 

Support Laboratory; ORD Publication Offices of Center for Environmental Research 

Information; Cincinnati, OH, 1984; EPA-600/4-84-017. 
SW-846 Update V TWO - 13 Revision 5 

July 2014

TABLE 2-1 

 DETERMINATIVE METHODS FOR ORGANIC ANALYTES 

 Analytes are listed in alphabetical order and alternative analyte names are in parenthesis. 

 The applicable method listing does not include immunoassay or screening methods. 

Analyte Applicable Method 

Abate (Temephos) ................................................................................................................ 8085 

Acenaphthene ............................................................................... 8100, 8270, 8275, 8310, 8410 

Acenaphthylene .............................................................................8100, 8270, 8275, 8310, 8410 

Acetaldehyde ........................................................................................................................ 8315 

Acetone................................................................................................... 8015, 8260, 8261, 8315 

Acetonitrile .............................................................................................. 8015, 8033, 8260, 8261 

Acetophenone ............................................................................................................. 8261, 8270 

2-Acetylaminofluorene .......................................................................................................... 8270 

1-Acetyl-2-thiourea ................................................................................................................ 8270 

Acifluorfen ................................................................................................................... 8085, 8151 

Acrolein (Propenal) ........................................................................8015, 8260, 8261, 8315, 8316 

Acrylamide .................................................................................................................. 8032, 8316 

Acrylonitrile ....................................................................................8015, 8031, 8260, 8261, 8316 

Alachlor ....................................................................................................................... 8081, 8085 

Aldicarb (Temik) .......................................................................................................... 8318, 8321 

Aldicarb sulfone .......................................................................................................... 8318, 8321 

Aldicarb sulfoxide .................................................................................................................. 8321 

Aldrin ................................................................................................................ 8081, 8085, 8270 

Allyl alcohol ................................................................................................................. 8015, 8260 

Allyl chloride ...................................................................................................... 8021, 8260, 8261 

Ametryn ................................................................................................................................ 8085 

2-Aminoanthraquinone .......................................................................................................... 8270 

Aminoazobenzene ................................................................................................................ 8270 

4-Aminobiphenyl ................................................................................................................... 8270 

Aminocarb ............................................................................................................................. 8321 

2-Amino-4,6-dinitrotoluene (2-Am-DNT) ...................................................................... 8095, 8330 

4-Amino-2,6-dinitrotoluene (4-Am-DNT) ...................................................................... 8095, 8330 

3-Amino-9-ethylcarbazole ..................................................................................................... 8270 

t-Amyl alcohol (TAA) ............................................................................................................. 8015 

t-Amyl ethyl ether (TAEE, 4,4-Dimethyl-3-oxahexane) ...................................... 8015, 8260, 8261 

t-Amyl methyl ether (TAME) .............................................................................. 8015, 8260, 8261 

Anilazine ............................................................................................................................... 8270 

Aniline ............................................................................................................... 8131, 8261, 8270 

o-Anisidine ............................................................................................................................ 8270 

Anthracene ....................................................................................8100, 8270, 8275, 8310, 8410 

Aramite ................................................................................................................................. 8270 

Aroclor-1016 (PCB-1016) ............................................................................................ 8082, 8270 

Aroclor-1221 (PCB-1221) ............................................................................................ 8082, 8270 

Aroclor-1232 (PCB-1232) ............................................................................................ 8082, 8270 

Aroclor-1242 (PCB-1242) ............................................................................................ 8082, 8270 

Aroclor-1248 (PCB-1248) ............................................................................................ 8082, 8270 

Aroclor-1254 (PCB-1254) ............................................................................................ 8082, 8270 
SW-846 Update V TWO - 14 Revision 5 

July 2014

Aroclor-1260 (PCB-1260) ............................................................................................ 8082, 8270 

Aspon ................................................................................................................................... 8141 

Asulam .................................................................................................................................. 8321 

Atraton .................................................................................................................................. 8085 

Atrazine............................................................................................................. 8041, 8085, 8141 

Azinphos-ethyl (Ethyl guthion) ..................................................................................... 8085, 8141 

Azinphos-methyl (Guthion) ................................................................................ 8085, 8141, 8270 

Barban ........................................................................................................................ 8270, 8321 

Baygon (Propoxur) ...................................................................................................... 8318, 8321 

Bendiocarb ........................................................................................................ 8141, 8318, 8321 

Benefin ................................................................................................................................. 8091 

Benfluralin ............................................................................................................................. 8085 

Benomyl ................................................................................................................................ 8321 

Bentazon ............................................................................................................................... 8151 

Benzal chloride ..................................................................................................................... 8121 

Benzaldehyde ....................................................................................................................... 8315 

Benz(a)anthracene ........................................................................8100, 8270, 8275, 8310, 8410 

Benzene.................................................................................................. 8015, 8021, 8260, 8261 

Benzenethiol (Thiophenol) .................................................................................................... 8270 

Benzidine .................................................................................................................... 8270, 8325 

Benzo(b)fluoranthene.............................................................................. 8100, 8270, 8275, 8310 

Benzo(j)fluoranthene ............................................................................................................. 8100 

Benzo(k)fluoranthene .............................................................................. 8100, 8270, 8275, 8310 

Benzoic acid ............................................................................................................... 8270, 8410 

Benzo(g,h,i)perylene ............................................................................... 8100, 8270, 8275, 8310 

Benzo(a)pyrene .............................................................................8100, 8270, 8275, 8310, 8410 

p-Benzoquinone .................................................................................................................... 8270 

Benzotrichloride .................................................................................................................... 8121 

Benzoylprop ethyl ................................................................................................................. 8325 

Benzyl alcohol ....................................................................................................................... 8270 

Benzyl chloride.................................................................................................. 8021, 8121, 8260 

α-BHC (α-Hexachlorocyclohexane) ......................................................... 8081, 8085, 8121, 8270 

β-BHC (β-Hexachlorocyclohexane) ......................................................... 8081, 8085, 8121, 8270 

δ-BHC (δ-Hexachlorocyclohexane) ......................................................... 8081, 8085, 8121, 8270 

γ-BHC (Lindane, γ-Hexachlorocyclohexane) ........................................... 8081, 8085, 8121, 8270 

Bis(2-n-butoxyethyl)phthalate ................................................................................................ 8061 

Bis(2-chloroethoxy)methane ............................................................................. 8111, 8270, 8410 

Bis(2-chloroethyl)ether ........................................................................... 8111, 8270, 8410, 8430 

Bis(2-chloroethyl)sulfide ........................................................................................................ 8260 

Bis(2-chloro-1-methylethyl)ether ............................................................. 8021, 8111, 8270, 8410 

Bis(2-ethoxyethyl)phthalate ................................................................................................... 8061 

Bis(2-ethylhexyl)phthalate ................................................................................. 8061, 8270, 8410 

Bis(2-methoxyethyl)phthalate ................................................................................................ 8061 

Bis(4-methyl-2-pentyl)phthalate ............................................................................................ 8061 

Bolstar (Sulprofos) ...................................................................................................... 8085, 8141 

Bromacil ...................................................................................................................... 8085, 8321 

Brominal (Bromoxynil) ................................................................................................. 8085, 8270 

Bromoacetone............................................................................................................. 8021, 8260 

4-Bromoaniline ...................................................................................................................... 8131 

Bromobenzene............................................................................................................ 8021, 8260 

Bromochloromethane ........................................................................................ 8021, 8260, 8261 
SW-846 Update V TWO - 15 Revision 5 

July 2014

2-Bromo-6-chloro-4-nitroaniline ............................................................................................. 8131 

Bromodichloromethane ..................................................................................... 8021, 8260, 8261 

2-Bromo-4,6-dinitroaniline ..................................................................................................... 8131 

Bromoform ....................................................................................................... 8021, 8260, 8261 

Bromomethane ................................................................................................. 8021, 8260, 8261 

4-Bromophenyl phenyl ether ................................................................... 8111, 8270, 8275, 8410 

Bromoxynil (Brominal) ................................................................................................. 8085, 8270 

Butachlor ............................................................................................................................... 8085 

Butanal ................................................................................................................................. 8315 

n-Butanol (1-Butanol, n-Butyl alcohol) ................................................................................... 8260 

2-Butanone (Methyl ethyl ketone, MEK) ............................................................ 8015, 8260, 8261 

Butifos (DEF) ........................................................................................................................ 8085 

Butralin ................................................................................................................................. 8091 

t-Butyl alcohol ............................................................................................................. 8015, 8260 

Butyl benzyl phthalate ....................................................................................... 8061, 8270, 8410 

Butylate ............................................................................................................. 8085, 8141, 8321 

n-Butylbenzene ................................................................................................. 8021, 8260, 8261 

sec-Butylbenzene ............................................................................................. 8021, 8260, 8261 

tert-Butylbenzene .............................................................................................. 8021, 8260, 8261 

2-sec-Butyl-4,6-dinitrophenol (DNBP, Dinoseb) .............................8041, 8085, 8151, 8270, 8321 

Captafol ............................................................................................................ 8081, 8085, 8270 

Captan ........................................................................................................................ 8085, 8270 

Carbaryl (Sevin) ...................................................................................... 8270, 8318, 8321, 8325 

Carbendazim ........................................................................................................................ 8321 

Carbofuran (Furaden) ....................................................................................... 8270, 8318, 8321 

Carbofuran phenol ................................................................................................................ 8321 

Carbon disulfide .......................................................................................................... 8260, 8261 

Carbon tetrachloride ............................................................................... 8021, 8260, 8261, 8535 

Carbophenothion .................................................................................... 8081, 8085, 8141, 8270 

Carbosulfan .......................................................................................................................... 8321 

Carboxin ............................................................................................................................... 8085 

Casoron (Dichlobenil) ............................................................................................................ 8085 

Chloral hydrate...................................................................................................................... 8260 

Chloramben .......................................................................................................................... 8151 

Chlordane (NOS) ........................................................................................................ 8081, 8270 

cis-Chlordane ........................................................................................................................ 8081 

trans-Chlordane .......................................................................................................... 8085, 8081 

Chlorfenvinphos .......................................................................................................... 8141, 8270 

Chloroacetonitrile .................................................................................................................. 8260 

2-Chloroaniline ...................................................................................................................... 8131 

3-Chloroaniline ...................................................................................................................... 8131 

4-Chloroaniline .................................................................................................. 8131, 8270, 8410 

Chlorobenzene.................................................................................................. 8021, 8260, 8261 

Chlorobenzilate ........................................................................................................... 8081, 8270 

2-Chlorobiphenyl ......................................................................................................... 8082, 8275 

2-Chloro-1,3-butadiene (Chloroprene) ........................................................................ 8021, 8260 

1-Chlorobutane ..................................................................................................................... 8260 

Chlorodibromomethane (Dibromochloromethane) ............................................. 8021, 8260, 8261 

2-Chloro-4,6-dinitroaniline ..................................................................................................... 8131 

1-Chloro-2,4-dinitrobenzene.................................................................................................. 8091 

1-Chloro-3,4-dinitrobenzene.................................................................................................. 8091 
SW-846 Update V TWO - 16 Revision 5 

July 2014

Chloroethane .................................................................................................... 8021, 8260, 8261 

2-Chloroethanol ................................................................................................ 8021, 8260, 8430 

2-(2-Chloroethoxy) ethanol.................................................................................................... 8430 

2-Chloroethyl vinyl ether ............................................................................................. 8021, 8260 

Chloroform ........................................................................................................ 8021, 8260, 8261 

1-Chlorohexane .................................................................................................................... 8260 

Chloromethane ................................................................................................. 8021, 8260, 8261 

5-Chloro-2-methylaniline ....................................................................................................... 8270 

Chloromethyl methyl ether .................................................................................................... 8021 

2-Chloro-5-methylphenol ....................................................................................................... 8041 

4-Chloro-2-methylphenol ....................................................................................................... 8041 

4-Chloro-3-methylphenol ................................................................................... 8041, 8270, 8410 

3-(Chloromethyl) pyridine hydrochloride ................................................................................ 8270 

1-Chloronaphthalene.................................................................................................. 8270, 8275 

2-Chloronaphthalene......................................................................................... 8121, 8270, 8410 

Chloroneb ............................................................................................................................. 8081 

2-Chloro-4-nitroaniline ........................................................................................................... 8131 

4-Chloro-2-nitroaniline ........................................................................................................... 8131 

1-Chloro-2-nitrobenzene ....................................................................................................... 8091 

1-Chloro-4-nitrobenzene ....................................................................................................... 8091 

2-Chloro-6-nitrotoluene ......................................................................................................... 8091 

4-Chloro-2-nitrotoluene ......................................................................................................... 8091 

4-Chloro-3-nitrotoluene ......................................................................................................... 8091 

2-Chlorophenol ................................................................................................. 8041, 8270, 8410 

3-Chlorophenol ..................................................................................................................... 8041 

4-Chlorophenol ..................................................................................................................... 8410 

2-Chlorophenyl 4-nitrophenyl ether ....................................................................................... 8111 

3-Chlorophenyl 4-nitrophenyl ether ....................................................................................... 8111 

4-Chlorophenyl 4-nitrophenyl ether ....................................................................................... 8111 

4-Chlorophenyl phenyl ether ............................................................................. 8111, 8270, 8410 

o-Chlorophenyl thiourea ........................................................................................................ 8325 

4-Chloro-1,2-phenylenediamine ............................................................................................ 8270 

4-Chloro-1,3-phenylenediamine ............................................................................................ 8270 

Chloroprene (2-Chloro-1,3-butadiene) ........................................................................ 8021, 8260 

Chloropropham ........................................................................................................... 8085, 8321 

Chloropropylate ..................................................................................................................... 8081 

Chlorothalonil ........................................................................................................................ 8081 

2-Chlorotoluene ................................................................................................ 8021, 8260, 8261 

4-Chlorotoluene ................................................................................................ 8021, 8260, 8261 

Chloroxuron .......................................................................................................................... 8321 

Chlorpyrifos ................................................................................................................. 8085, 8141 

Chlorpyrifos methyl ............................................................................................................... 8141 

Chlorthalonil (Daconil) ........................................................................................................... 8085 

Chrysene .......................................................................................8100, 8270, 8275, 8310, 8410 

Coumaphos ..................................................................................................... 8085, 8141, 8270 

p-Cresidine ........................................................................................................................... 8270 

o-Cresol (2-Methylphenol) ................................................................................. 8041, 8270, 8410 

m-Cresol (3-Methylphenol) .......................................................................................... 8041, 8270 

p-Cresol (4-Methylphenol) ................................................................................. 8041, 8270, 8410 

Crotonaldehyde ................................................................................................. 8015, 8260, 8315 

Crotoxyphos ................................................................................................................ 8141, 8270 
SW-846 Update V TWO - 17 Revision 5 

July 2014

m-Cumenyl methylcarbamate ..................................................................................... 8318, 8321 

Cyanazine ............................................................................................................................. 8085 

Cycloate ................................................................................................................................ 8085 

Cyclohexane ......................................................................................................................... 8260 

Cyclohexanone ..................................................................................................................... 8315 

2-Cyclohexyl-4,6-dinitrophenol .................................................................................... 8041, 8270 

2,4-D ........................................................................................................................... 8151, 8321 

2,4-D (acid) ........................................................................................................................... 8085 

2,4-D (butoxyethanol ester) ................................................................................................... 8321 

2,4-D (ethylhexyl ester) ......................................................................................................... 8321 

Daconil (Chlorthalonil) ........................................................................................................... 8085 

Dacthal (DCPA) .......................................................................................................... 8081, 8085 

Dalapon ...................................................................................................................... 8151, 8321 

2,4-DB ........................................................................................................................ 8151, 8321 

2,4-DB (acid) ......................................................................................................................... 8085 

DBCP (1,2-Dibromo-3-chloropropane) ................................. 8011, 8021, 8081, 8260, 8261, 8270 

DCM (Dichloromethane, Methylene chloride) .................................................... 8021, 8260, 8261 

DCPA (Dacthal) .......................................................................................................... 8081, 8085 

DCPA diacid ......................................................................................................................... 8151 

2,4'-DDD ............................................................................................................................... 8085 

4,4'-DDD ........................................................................................................... 8081, 8085, 8270 

2,4'-DDE ............................................................................................................................... 8085 

4,4'-DDE ........................................................................................................... 8081, 8085, 8270 

2,4'-DDT ............................................................................................................................... 8085 

4,4'-DDT ........................................................................................................... 8081, 8085, 8270 

DDVP (Dichlorvos, Dichlorovos) ............................................................. 8085, 8141, 8270, 8321 

2,2',3,3'4,4'5,5',6,6'-Decachlorobiphenyl ............................................................................... 8275 

Decanal................................................................................................................................. 8315 

DEF (Butifos) ........................................................................................................................ 8085 

Demeton-O, and Demeton-S ............................................................................. 8085, 8141, 8270 

Diallate .............................................................................................................. 8081, 8085, 8270 

2,4-Diaminotoluene ............................................................................................................... 8270 

Diamyl phthalate ................................................................................................................... 8061 

Diazinon ...................................................................................................................... 8085, 8141 

Dibenz(a,h)acridine ............................................................................................................... 8100 

Dibenz(a,j)acridine ...................................................................................................... 8100, 8270 

Dibenz(a,h)anthracene ............................................................................ 8100, 8270, 8275, 8310 

7H-Dibenzo(c,g)carbazole .................................................................................................... 8100 

Dibenzofuran .................................................................................................... 8270, 8275, 8410 

Dibenzo(a,e)pyrene .................................................................................................... 8100, 8270 

Dibenzo(a,h)pyrene .............................................................................................................. 8100 

Dibenzo(a,i)pyrene ................................................................................................................ 8100 

Dibenzothiophene ................................................................................................................. 8275 

Dibromochloromethane (Chlorodibromomethane) ............................................. 8021, 8260, 8261 

1,2-Dibromo-3-chloropropane (DBCP) ................................. 8011, 8021, 8081, 8260, 8261, 8270 

Dibromomethane .............................................................................................. 8021, 8260, 8261 

1,2-Dibromoethane (EDB, Ethylene dibromide) ................................................. 8011, 8021, 8260 

2,6-Dibromo-4-nitroaniline ..................................................................................................... 8131 

2,4-Dibromophenyl 4-nitrophenyl ether ................................................................................. 8111 

Dibutyltin dichloride ............................................................................................................... 8323 

Di-n-butyl phthalate ........................................................................................... 8061, 8270, 8410 
SW-846 Update V TWO - 18 Revision 5 

July 2014

Dicamba............................................................................................................ 8085, 8151, 8321 

Dichlobenil (Casoron) ............................................................................................................ 8085 

Dichlone ...................................................................................................................... 8081, 8270 

Dichloran ............................................................................................................................... 8081 

3,4-Dichloroaniline ................................................................................................................ 8131 

1,2-Dichlorobenzene ............................................................ 8021, 8121, 8260, 8261, 8270, 8410 

1,3-Dichlorobenzene ............................................................ 8021, 8121, 8260, 8261, 8270, 8410 

1,4-Dichlorobenzene ............................................................ 8021, 8121, 8260, 8261, 8270, 8410 

3,3'-Dichlorobenzidine .................................................................................................. 8270,8325 

3,5-Dichlorobenzoic acid ............................................................................................. 8085, 8151 

2,3-Dichlorobiphenyl ............................................................................................................. 8082 

3,3'-Dichlorobiphenyl ............................................................................................................. 8275 

cis-1,4-Dichloro-2-butene ............................................................................................ 8260, 8261 

trans-1,4-Dichloro-2-butene ........................................................................................ 8260, 8261 

Dichlorodifluoromethane ................................................................................... 8021, 8260, 8261 

1,1-Dichloroethane ............................................................................................ 8021, 8260, 8261 

1,2-Dichloroethane ............................................................................................ 8021, 8260, 8261 

1,1-Dichloroethene (Vinylidene chloride) ........................................................... 8021, 8260, 8261 

cis-1,2-Dichloroethene ...................................................................................... 8021, 8260, 8261 

trans-1,2-Dichloroethene ................................................................................... 8021, 8260, 8261 

Dichlorofenthion .................................................................................................................... 8141 

Dichloromethane (DCM, Methylene chloride) .................................................... 8021, 8260, 8261 

2,6-Dichloro-4-nitroaniline ..................................................................................................... 8131 

2,3-Dichloronitrobenzene ...................................................................................................... 8091 

2,4-Dichloronitrobenzene ...................................................................................................... 8091 

2,5-Dichloronitrobenzene ...................................................................................................... 8091 

3,4-Dichloronitrobenzene ...................................................................................................... 8091 

3,5-Dichloronitrobenzene ...................................................................................................... 8091 

2,3-Dichlorophenol ................................................................................................................ 8041 

2,4-Dichlorophenol ............................................................................................ 8041, 8270, 8410 

2,5-Dichlorophenol ................................................................................................................ 8041 

2,6-Dichlorophenol ...................................................................................................... 8041, 8270 

3,4-Dichlorophenol ................................................................................................................ 8041 

3,5-Dichlorophenol ................................................................................................................ 8041 

2,4-Dichlorophenol 3-methyl-4-nitrophenyl ether ................................................................... 8111 

2,3-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

2,4-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

2,5-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

2,6-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

3,4-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

3,5-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

Dichloroprop (Dichlorprop) ................................................................................ 8085, 8151, 8321 

1,2-Dichloropropane ......................................................................................... 8021, 8260, 8261 

1,3-Dichloropropane ......................................................................................... 8021, 8260, 8261 

2,2-Dichloropropane ......................................................................................... 8021, 8260, 8261 

1,3-Dichloro-2-propanol .............................................................................................. 8021, 8260 

1,1-Dichloropropene ......................................................................................... 8021, 8260, 8261 

cis-1,3-Dichloropropene .................................................................................... 8021, 8260, 8261 

trans-1,3-Dichloropropene ................................................................................ 8021, 8260, 8261 

Dichlorovos (DDVP, Dichlorvos) ............................................................. 8085, 8141, 8270, 8321 

Dichlorprop (Dichloroprop) ................................................................................ 8085, 8151, 8321 
SW-846 Update V TWO - 19 Revision 5 

July 2014

Diclofol (Kelthane) ................................................................................................................ 8085 

Diclofop-methyl ................................................................................................................... 8085 

Dicofol ................................................................................................................................. 8081 

Dicrotophos ................................................................................................................. 8141, 8270 

Dicyclohexyl phthalate .......................................................................................................... 8061 

Dieldrin ............................................................................................................. 8081, 8085, 8270 

1,2,3,4-Diepoxybutane .......................................................................................................... 8260 

Diesel range organics (DRO) ................................................................................................ 8015 

Diethyl ether ...................................................................................................... 8015, 8260, 8261 

Diethyl phthalate ............................................................................................... 8061, 8270, 8410 

Diethyl sulfate ....................................................................................................................... 8270 

Diethylene glycol ................................................................................................................... 8430 

Diethylstilbestrol .................................................................................................................... 8270 

Dihexyl phthalate .................................................................................................................. 8061 

Diisobutyl phthalate ............................................................................................................... 8061 

Diisopropyl ether (DIPE) ................................................................................... 8015, 8260, 8261 

Dimethoate ............................................................................................. 8141, 8270, 8085, 8321 

3,3'-Dimethoxybenzidine ............................................................................................. 8270, 8325 

Dimethyl phthalate ............................................................................................ 8061, 8270, 8410 

Dimethylaminoazobenzene ................................................................................................... 8270 

2,5-Dimethylbenzaldehyde .................................................................................................... 8315 

7,12-Dimethylbenz(a)anthracene .......................................................................................... 8270 

3,3'-Dimethylbenzidine ................................................................................................ 8270, 8325 

4,4-Dimethyl-3-oxahexane (t-Amyl ethyl ether, TAEE) ...................................... 8015, 8260, 8261 

α,α-Dimethylphenethylamine ................................................................................................. 8270 

2,3-Dimethylphenol ............................................................................................................... 8041 

2,4-Dimethylphenol ..................................................................................................... 8041, 8270 

2,5-Dimethylphenol ............................................................................................................... 8041 

2,6-Dimethylphenol ............................................................................................................... 8041 

3,4-Dimethylphenol ............................................................................................................... 8041 

Dinitramine ............................................................................................................................ 8091 

2,4-Dinitroaniline .................................................................................................................. 8131 

3,5-Dinitroaniline ......................................................................................................... 8095, 8330 

1,2-Dinitrobenzene ...................................................................................................... 8091, 8270 

1,3-Dinitrobenzene (1,3-DNB) ................................................................. 8091, 8095, 8270, 8330 

1,4-Dinitrobenzene ...................................................................................................... 8091, 8270 

4,6-Dinitro-2-methylphenol .......................................................................................... 8270, 8410 

2,4-Dinitrophenol ............................................................................................... 8041, 8270, 8410 

2,5-Dinitrophenol ................................................................................................................... 8041 

2,4-Dinitrotoluene (2,4-DNT) ..........................................................8091, 8095, 8270, 8330, 8410 

2,6-Dinitrotoluene (2,6-DNT) ..........................................................8091, 8095, 8270, 8330, 8410 

Dinocap................................................................................................................................. 8270 

Dinonyl phthalate .................................................................................................................. 8061 

Dinoseb (2-sec-Butyl-4,6-dinitrophenol, DNBP) .............................8041, 8085, 8151, 8270, 8321 

Di-n-octyl phthalate ........................................................................................... 8061, 8270, 8410 

Dioxacarb .............................................................................................................................. 8318 

1,4-Dioxane ................................................................................................................ 8260, 8261 

Dioxathion ................................................................................................................... 8085, 8141 

DIPE (Diisopropyl ether) ............................................................................................. 8015, 8261 

Diphenamid ........................................................................................................................... 8085 

Diphenylamine ...................................................................................................................... 8270 
SW-846 Update V TWO - 20 Revision 5 

July 2014

5,5-Diphenylhydantoin .......................................................................................................... 8270 

1,2-Diphenylhydrazine .......................................................................................................... 8270 

Diphenyltin dichloride ............................................................................................................ 8323 

Di-n-propyl phthalate ............................................................................................................. 8410 

Disperse Blue 3 ..................................................................................................................... 8321 

Disperse Blue 14 ................................................................................................................... 8321 

Disperse Brown 1 .................................................................................................................. 8321 

Disperse Orange 3 ................................................................................................................ 8321 

Disperse Orange 30 .............................................................................................................. 8321 

Disperse Red 1 ..................................................................................................................... 8321 

Disperse Red 5 ..................................................................................................................... 8321 

Disperse Red 13 ................................................................................................................... 8321 

Disperse Red 60 ................................................................................................................... 8321 

Disperse Yellow 5 ................................................................................................................. 8321 

Disulfoton ................................................................................................ 8085, 8141, 8270, 8321 

Diuron ............................................................................................................... 8085, 8321, 8325 

1,3-DNB (1,3-Dinitrobenzene) ................................................................. 8091, 8095, 8270, 8330 

DNBP (2-sec-Butyl-4,6-dinitrophenol, Dinoseb) .............................8041, 8085, 8151, 8270, 8321 

2,4-DNT (2,4-Dinitrotoluene) ..........................................................8091, 8095, 8270, 8330, 8410 

2,6-DNT (2,6-Dinitrotoluene) ................................................................... 8091, 8270, 8330, 8410 

EDB (1,2-Dibromoethane, Ethylene dibromide) ................................................. 8011, 8021, 8260 

Endosulfan I ...................................................................................................... 8081, 8085, 8270 

Endosulfan II ..................................................................................................... 8081, 8085, 8270 

Endosulfan sulfate ............................................................................................ 8081, 8085, 8270 

Endrin ............................................................................................................... 8081, 8085, 8270 

Endrin aldehyde ................................................................................................ 8081, 8085, 8270 

Endrin ketone .................................................................................................... 8081, 8085, 8270 

Epichlorohydrin ........................................................................................................... 8021, 8260 

EPN .................................................................................................................. 8141, 8085, 8270 

Eptam (EPTC)................................................................................................... 8085, 8141, 8321 

EPTC (Eptam)................................................................................................... 8085, 8141, 8321 

ETBE (Ethyl tert-butyl ether) ....................................................................................... 8015, 8261 

Ethalfluralin (Sonalan) ........................................................................................................... 8085 

Ethanol ............................................................................................................. 8015, 8260, 8261 

Ethion ............................................................................................................... 8085, 8141, 8270 

Ethoprop ..................................................................................................................... 8085, 8141 

Ethyl acetate ..................................................................................................... 8015, 8260, 8261 

Ethyl benzene ......................................................................................... 8015, 8021, 8260, 8261 

Ethyl t-butyl ether (ETBE) ................................................................................. 8015, 8260, 8261 

Ethyl carbamate .................................................................................................................... 8270 

Ethyl cyanide (Propionitrile)............................................................................... 8015, 8260, 8261 

Ethyl guthion (Azinphos-ethyl) ..................................................................................... 8085, 8141 

Ethyl methacrylate ...................................................................................................... 8260, 8261 

Ethyl methanesulfonate ......................................................................................................... 8270 

Ethylene dibromide (EDB, 1,2-Dibromoethane) ................................................. 8011, 8021, 8260 

Ethylene glycol ...................................................................................................................... 8430 

Ethylene oxide ............................................................................................................ 8015, 8260 

Etridiazole ............................................................................................................................. 8081 

Famphur ........................................................................................................... 8141, 8270, 8321 

Fenamiphos .......................................................................................................................... 8085 

Fenarimol .............................................................................................................................. 8085 
SW-846 Update V TWO - 21 Revision 5 

July 2014

Fenitrothion ................................................................................................................. 8085, 8141 

Fensulfothion .......................................................................................... 8085, 8141, 8270, 8321 

Fenthion ............................................................................................................ 8085, 8141, 8270 

Fenuron ................................................................................................................................ 8321 

Fluchloralin ........................................................................................................................... 8270 

Fluometuron .......................................................................................................................... 8321 

Fluoranthene ..................................................................................8100, 8270, 8275, 8310, 8410 

Fluorene.........................................................................................8100, 8270, 8275, 8310, 8410 

Fluridone ............................................................................................................................... 8085 

Fonophos .................................................................................................................... 8085, 8141 

Formaldehyde ....................................................................................................................... 8315 

Formetanate hydrochloride ......................................................................................... 8318, 8321 

Furaden (Carbofuran) ....................................................................................... 8270, 8318, 8321 

Gardona (Tetrachlovinphos, Stirophos) ............................................................... 80858141, 8270 

Garlon (Triclopyr) .................................................................................................................. 8085 

Gasoline range organics (GRO) ............................................................................................ 8015 

Guthion (Azinphos-methyl) ................................................................................ 8085, 8141, 8270 

Halowax-1000 ....................................................................................................................... 8081 

Halowax-1001 ....................................................................................................................... 8081 

Halowax-1013 ....................................................................................................................... 8081 

Halowax-1014 ....................................................................................................................... 8081 

Halowax-1051 ....................................................................................................................... 8081 

Halowax-1099 ....................................................................................................................... 8081 

Heptachlor ........................................................................................................ 8081, 8085, 8270 

Heptachlor epoxide ........................................................................................... 8081, 8085, 8270 

2,2',3,3',4,4',5-Heptachlorobiphenyl ............................................................................ 8082, 8275 

2,2',3,4,4',5,5'-Heptachlorobiphenyl ............................................................................ 8082, 8275 

2,2',3,4,4',5',6-Heptachlorobiphenyl ...................................................................................... 8082 

2,2',3,4',5,5',6-Heptachlorobiphenyl ............................................................................ 8082, 8275 

Heptanal ............................................................................................................................... 8315 

Hexachlorobenzene ............................................................. 8081, 8085, 8121, 8270, 8275, 8410 

2,2',3,3,4,4'-Hexachlorobiphenyl ........................................................................................... 8275 

2,2',3,4,4',5'-Hexachlorobiphenyl ................................................................................. 8082, 8275 

2,2',3,4,5,5'-Hexachlorobiphenyl ........................................................................................... 8082 

2,2',3,5,5',6-Hexachlorobiphenyl ........................................................................................... 8082 

2,2',4,4',5,5'-Hexachlorobiphenyl ........................................................................................... 8082 

2-exo,3-endo,6-exo,8,9,10-Hexachlorobornane (Hx-Sed) ..................................................... 8276 

Hexachlorobutadiene (1,3-Hexachlorobutadiene) ................ 8021, 8121, 8260, 8261, 8270, 8410 

α-Hexachlorocyclohexane (α-BHC) ......................................................... 8081, 8085, 8121, 8270 

β-Hexachlorocyclohexane (β-BHC) ......................................................... 8081, 8085, 8121, 8270 

δ-Hexachlorocyclohexane (δ-BHC) ......................................................... 8081, 8085, 8121, 8270 

γ-Hexachlorocyclohexane (γ-BHC, Lindane) ........................................... 8081, 8085, 8121, 8270 

Hexachlorocyclopentadiene ...........................................................8081, 8085, 8121, 8270, 8410 

Hexachloroethane ................................................................................... 8121, 8260, 8270, 8410 

Hexachlorophene .................................................................................................................. 8270 

Hexachloropropene ..................................................................................................... 8141, 8270 

Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) .................................................... 8095, 8330, 8510 

Hexamethyl phosphoramide (HMPA) .................................................................................. , 8270 

Hexanal................................................................................................................................. 8315 

2-Hexanone ................................................................................................................ 8260, 8261 

Hexazinone ........................................................................................................................... 8085 
SW-846 Update V TWO - 22 Revision 5 

July 2014

Hexyl 2-ethylhexyl phthalate ................................................................................................. 8061 

HMPA (Hexamethyl phosphoramide) .......................................................................... 8141, 8270 

HMX (Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine) ............................................... 8095, 8330 

1,2,3,4,6,7,8-HpCDD................................................................................................... 8280, 8290 

HpCDD, total ............................................................................................................... 8280, 8290 

1,2,3,4,6,7,8-HpCDF ................................................................................................... 8280, 8290 

1,2,3,4,7,8,9-HpCDF ................................................................................................... 8280, 8290 

HpCDF, total ............................................................................................................... 8280, 8290 

1,2,3,4,7,8-HxCDD ...................................................................................................... 8280, 8290 

1,2,3,6,7,8-HxCDD ...................................................................................................... 8280, 8290 

1,2,3,7,8,9-HxCDD ...................................................................................................... 8280, 8290 

HxCDD, total ............................................................................................................... 8280, 8290 

1,2,3,4,7,8-HxCDF ...................................................................................................... 8280, 8290 

1,2,3,6,7,8-HxCDF ...................................................................................................... 8280, 8290 

1,2,3,7,8,9-HxCDF ...................................................................................................... 8280, 8290 

2,3,4,6,7,8-HxCDF ...................................................................................................... 8280, 8290 

HxCDF ........................................................................................................................ 8280, 8290 

Hydroquinone ....................................................................................................................... 8270 

3-Hydroxycarbofuran................................................................................................... 8318, 8321 

5-Hydroxydicamba ................................................................................................................ 8151 

Igran (Terbutryn) ................................................................................................................... 8085 

Imidan (Phosmet) .............................................................................................. 8085, 8141, 8270 

Indeno(1,2,3-cd)pyrene ........................................................................... 8100, 8270, 8275, 8310 

Iodomethane (Methyl iodide) ....................................................................................... 8260, 8261 

Ioxynil ................................................................................................................................... 8085 

Isobutyl alcohol (2-Methyl-1-propanol) ........................................................................ 8260, 8261 

Isodrin ......................................................................................................................... 8081, 8270 

Isophorone .................................................................................................................. 8270, 8410 

Isopropalin ............................................................................................................................ 8091 

Isopropyl alcohol (2-Propanol) .................................................................................... 8015, 8260 

Isopropylbenzene ........................................................................................................ 8021, 8260 

p-Isopropyltoluene ............................................................................................ 8021, 8260, 8261 

Isosafrole .............................................................................................................................. 8270 

Isovaleraldehyde ................................................................................................................... 8315 

Kelthane (Diclofol) ................................................................................................................. 8085 

Kepone ................................................................................................................................. 8270 

Kerb (Pronamide) ...................................................................................................... 8085, 8270 

Lannate (Methomyl) .................................................................................................... 8318, 8321 

Leptophos ................................................................................................................... 8141, 8270 

Lindane (γ-Hexachlorocyclohexane, γ-BHC) ........................................... 8081, 8085, 8121, 8270 

Linuron (Lorox)............................................................................................................ 8321, 8325 

Lorox (Linuron)............................................................................................................ 8321, 8325 

Malathion ......................................................................................................... 8085, 8141, 8270 

Maleic anhydride ................................................................................................................... 8270 

Malononitrile ......................................................................................................................... 8260 

MCPA ......................................................................................................................... 8151, 8321 

MCPA (acid) ......................................................................................................................... 8085 

MCPP ......................................................................................................................... 8151, 8321 

MCPP (acid) ......................................................................................................................... 8085 

MEK (Methyl ethyl ketone, 2-Butanone) ............................................................ 8015, 8260, 8261 

Merphos ............................................................................................................ 8085, 8141, 8321 
SW-846 Update V TWO - 23 Revision 5 

July 2014

Mestranol .............................................................................................................................. 8270 

Mesurol (Methiocarb) ........................................................................................ 8141, 8318, 8321 

Methacrylonitrile .......................................................................................................... 8260, 8261 

Metalaxyl ............................................................................................................................... 8085 

Methanol ..................................................................................................................... 8015, 8260 

Methapyrilene ....................................................................................................................... 8270 

Methiocarb (Mesurol) ........................................................................................ 8141, 8318, 8321 

Methomyl (Lannate) .................................................................................................... 8318, 8321 

Methoxychlor .................................................................................................... 8081, 8085, 8270 

Methyl acrylate ...................................................................................................................... 8260 

Methyl-t-butyl ether (MTBE) .............................................................................. 8015, 8260, 8261 

Methyl chlorpyrifos ................................................................................................................ 8085 

Methyl ethyl ketone (MEK, 2-Butanone) ............................................................ 8015, 8260, 8261 

Methyl iodide (Iodomethane) ....................................................................................... 8260, 8261 

Methyl isobutyl ketone (MIBK, 4-Methyl-2-pentanone) ................................................ 8260, 8261 

Methyl methacrylate .................................................................................................... 8260, 8261 

Methyl methanesulfonate ...................................................................................................... 8270 

Methyl paraoxon ................................................................................................................... 8085 

Methyl parathion (Parathion, methyl) ....................................................... 8085, 8270, 8141, 8321 

3-Methylcholanthrene.................................................................................................. 8100, 8270 

Methylcyclohexane ............................................................................................................... 8270 

2-Methyl-4,6-dinitrophenol .................................................................................................... 8041 

Methylene chloride (Dichloromethane, DCM) .................................................... 8021, 8260, 8261 

4,4'-Methylenebis (2-chloroaniline) ........................................................................................ 8270 

4,4'-Methylenebis (N,N-dimethylaniline) ................................................................................ 8270 

1-Methylnaphthalene............................................................................................................. 8261 

2-Methylnaphthalene......................................................................................... 8261, 8270, 8410 

4-Methyl-2-pentanone (MIBK, Methyl isobutyl ketone) ................................................ 8260, 8261 

2-Methylphenol (o-Cresol) ................................................................................. 8041, 8270, 8410 

3-Methylphenol (m-Cresol) .......................................................................................... 8041, 8270 

4-Methylphenol (p-Cresol) ................................................................................. 8041, 8270, 8410 

2-Methyl-1-propanol (Isobutyl alcohol) ........................................................................ 8260, 8261 

2-Methyl-2-propanol (t-Butyl alcohol) .......................................................................... 8015, 8260 

2-Methylpyridine (2-Picoline) ..................................................................... 8015, 8260, 82618270 

Methyl-2,4,6-trinitrophenyl-nitramine (Tetryl) ......................................................................... 8330 

Metolachlor ........................................................................................................................... 8085 

Metolcarb .................................................................................................................... 8318, 8321 

Metribuzin ............................................................................................................................. 8085 

Mevinphos ........................................................................................................ 8085, 8141, 8270 

Mexacarbate ..................................................................................................... 8270, 8318, 8321 

MGK-264 .............................................................................................................................. 8085 

MIBK (Methyl isobutyl ketone, 4-Methyl-2-pentanone) ................................................ 8260, 8261 

Mirex ................................................................................................................. 8081, 8085, 8270 

Molinate ............................................................................................................ 8085, 8141, 8321 

Monobutyltin trichloride ......................................................................................................... 8323 

Monocrotophos ................................................................................................. 8141, 8270, 8321 

Monophenyltin trichloride ...................................................................................................... 8323 

Monuron...................................................................................................................... 8321, 8325 

MTBE (Methyl-t-butyl ether) .............................................................................. 8015, 8260, 8261 

Naled ................................................................................................................ 8141, 8270, 8321 

Naphthalene .................................................... 8021, 8100, 8260, 8261, 8270, 8275, 8310, 8410 
SW-846 Update V TWO - 24 Revision 5 

July 2014

Napropamide ........................................................................................................................ 8085 

1,2-Naphthoquinone ............................................................................................................. 8091 

1,4-Naphthoquinone ................................................................................................... 8270, 8091 

1-Naphthylamine ................................................................................................................... 8270 

2-Naphthylamine ................................................................................................................... 8270 

NB (Nitrobenzene) ............................................................... 8091, 8095, 8260, 8270, 8330, 8410 

Neburon ................................................................................................................................ 8321 

Nicotine ................................................................................................................................. 8270 

5-Nitroacenaphthene............................................................................................................. 8270 

2-Nitroaniline ..................................................................................................... 8131, 8270, 8410 

3-Nitroaniline ..................................................................................................... 8131, 8270, 8410 

4-Nitroaniline ..................................................................................................... 8131, 8270, 8410 

5-Nitro-o-anisidine ................................................................................................................. 8270 

Nitrobenzene (NB) ............................................................... 8091, 8095, 8260, 8270, 8330, 8410 

4-Nitrobiphenyl ...................................................................................................................... 8270 

Nitrofen ....................................................................................................................... 8081, 8270 

Nitroglycerin ...................................................................................................... 8095, 8330, 8332 

2-Nitrophenol ................................................................................................... 8041, 8270, 8410 

3-Nitrophenol ....................................................................................................................... 8041 

4-Nitrophenol .................................................................................8041, 8085, 8151, 8270, 8410 

4-Nitrophenyl phenyl ether .................................................................................................... 8111 

2-Nitropropane ...................................................................................................................... 8260 

Nitroquinoline-1-oxide ........................................................................................................... 8270 

N-Nitroso-di-n-butylamine (N-Nitrosodibutylamine) ................................. 8015, 8260, 8261, 8270 

N-Nitrosodiethylamine ................................................................................................. 8261, 8270 

N-Nitrosodimethylamine .......................................................................... 8070, 8261, 8270, 8410 

N-Nitrosodiphenylamine .................................................................................... 8070, 8270, 8410 

N-Nitroso-di-n-propylamine ..................................................................... 8070, 8261, 8270, 8410 

N-Nitrosomethylethylamine ......................................................................................... 8261, 8270 

N-Nitrosomorpholine ............................................................................................................. 8270 

N-Nitrosopiperidine ............................................................................................................... 8270 

N-Nitrosopyrrolidine .............................................................................................................. 8270 

2-Nitrotoluene (o-Nitrotoluene, 2-NT) ................................................................ 8091, 8095, 8330

3-Nitrotoluene (m-Nitrotoluene, 3-NT) ............................................................... 8091, 8095, 8330 

4-Nitrotoluene (p-Nitrotoluene, 4-NT) ................................................................ 8091, 8095, 8330

5-Nitro-o-toluidine ................................................................................................................. 8270 

trans-Nonachlor .................................................................................................................... 8081 

2,2'3,3'4,4'5,5'6-Nonachlorobiphenyl ........................................................................... 8082, 8275 

2,2,5,5,8,9,9,10,10-Nonachlorobornane (P62) ...................................................................... 8276 

2-endo,3-exo,5-endo,6-exo,8,8,9,10,10-Nonachlorobornane (P50)....................................... 8276 

Nonanal ................................................................................................................................ 8315 

Norflurazon ........................................................................................................................... 8085 

2-NT (2-Nitrotoluene, o-Nitrotoluene) ................................................................ 8091, 8095, 8330 

3-NT (3-Nitrotoluene, m-Nitrotoluene) ............................................................... 8091, 8095, 8330 

4-NT (4-Nitrotoluene, p-Nitrotoluene) ................................................................ 8091, 8095, 8330 

OCDD ......................................................................................................................... 8280, 8290 

OCDF ......................................................................................................................... 8280, 8290 

2,2',3,3',4,4'5,5'-Octachlorobiphenyl ...................................................................................... 8275 

2-endo,3-exo,5-endo,6-exo,8,8,10,10-Octachlorobornane (P26) .......................................... 8276 

2-endo,3-exo,5-endo,6-exo,8,9,10,10-Octachlorobornane (P40) .......................................... 8276 

2-exo,3-endo,5-exo,8,9,9,10,10-Octachlorobornane (P41) ................................................... 8276 
SW-846 Update V TWO - 25 Revision 5 

July 2014

2-exo,5,5,8,9,9,10,10-Octachlorobornane (P44) ................................................................... 8276 

Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) ............................................... 8095, 8330 

Octamethyl pyrophosphoramide ........................................................................................... 8270 

Octanal ................................................................................................................................. 8315 

Oxamyl ...................................................................................................................... 8318, 8321 

4,4'-Oxydianiline ................................................................................................................... 8270 

Oxyfluorfen ........................................................................................................................... 8085 

Paraldehyde ................................................................................................................ 8015, 8260 

Parathion .................................................................................................................... 8085, 8270 

Parathion, ethyl ..................................................................................................................... 8141 

Parathion, methyl .................................................................................... 8085, 8270, 8141, 8321 

PCB-1016 (Aroclor-1016) ............................................................................................ 8082, 8270 

PCB-1221 (Aroclor-1221) ............................................................................................ 8082, 8270 

PCB-1232 (Aroclor-1232) ............................................................................................ 8082, 8270 

PCB-1242 (Aroclor-1242) ............................................................................................ 8082, 8270 

PCB-1248 (Aroclor-1248) ............................................................................................ 8082, 8270 

PCB-1254 (Aroclor-1254) ............................................................................................ 8082, 8270 

PCB-1260 (Aroclor-1260) ............................................................................................ 8082, 8270 

PCBs, as congeners ............................................................................................................. 8082 

PCNB (Pentachloronitrobenzene) ..................................................................... 8081, 8091, 8270 

Pebulate............................................................................................................ 8085, 8141, 8321 

1,2,3,7,8-PeCDD ......................................................................................................... 8280, 8290 

PeCDD, total ............................................................................................................... 8280, 8290 

1,2,3,7,8-PeCDF ......................................................................................................... 8280, 8290 

2,3,4,7,8-PeCDF ......................................................................................................... 8280, 8290 

PeCDF, total ............................................................................................................... 8280, 8290 

Pendimethaline (Penoxalin) ........................................................................................ 8085, 8091 

Penoxalin (Pendimethaline) ........................................................................................ 8085, 8091 

Pentachlorobenzene ................................................................................................... 8121, 8270 

2,2',3,4,5'-Pentachlorobiphenyl ............................................................................................. 8082 

2,3',4,4',5-Pentachlorobiphenyl ............................................................................................. 8275 

2,2',4,5,5'-Pentachlorobiphenyl ................................................................................... 8082, 8275 

2,3,3',4',6-Pentachlorobiphenyl ............................................................................................. 8082 

Pentachloroethane ...................................................................................................... 8260, 8261 

Pentachloronitrobenzene (PCNB) ..................................................................... 8081, 8091, 8270 

Pentachlorophenol .........................................................................8041, 8085, 8151, 8270, 8410 

Pentaerythritol tetranitrate (PETN) .............................................................................. 8095, 8330 

Pentafluorobenzene .............................................................................................................. 8260 

Pentanal (Valeraldehyde) ...................................................................................................... 8315 

2-Pentanone ............................................................................................................... 8015, 8260 

Perchloroethylene (Tetrachloroethene, Tetrachloroethylene) ............................ 8021, 8260, 8261 

Permethrin (cis + trans) ......................................................................................................... 8081 

Perthane ............................................................................................................................... 8081 

Phenacetin ............................................................................................................................ 8270 

Phenanthrene ................................................................................8100, 8270, 8275, 8310, 8410 

Phenobarbital ........................................................................................................................ 8270 

Phenol .............................................................................................................. 8041, 8270, 8410 

1,4-Phenylenediamine .......................................................................................................... 8270 

1,2-Phenylenediamine (o-Phenylenediamine) ............................................................. 8141, 8321 

Phorate ................................................................................................... 8085, 8141, 8270, 8321 

Phosalone ............................................................................................................................. 8270 
SW-846 Update V TWO - 26 Revision 5 

July 2014

Phosmet (Imidan) .............................................................................................. 8085, 8141, 8270 

Phosphamidon .................................................................................................. 8085, 8141, 8270 

Phthalic anhydride ................................................................................................................ 8270 

Physostigmine....................................................................................................................... 8321 

Physostigmine salicylate ....................................................................................................... 8321 

Picloram ...................................................................................................................... 8085, 8151 

2-Picoline (2-Methylpyridine) ................................................................... 8015, 8260, 8261, 8270 

Piperonyl sulfoxide ................................................................................................................ 8270 

Polychlorinated biphenyls (PCBs), as Aroclors or congeners ..................................... 8082, 8270 

Pramitol 5p (Prometon) ......................................................................................................... 8085 

Profluralin .................................................................................................................... 8085, 8091 

Promecarb .................................................................................................................. 8318, 8321 

Prometon (Pramitol 5p) ......................................................................................................... 8085 

Prometryn ............................................................................................................................. 8085 

Pronamide (Kerb) ....................................................................................................... 8085, 8270 

Propachlor (Ramrod)................................................................................................... 8081, 8085 

Propanal (Propionaldehyde) .................................................................................................. 8315 

1-Propanol (n-Propyl alcohol) ...................................................................................... 8015, 8260 

2-Propanol (Isopropyl alcohol) ................................................................................... 8015, 8260 

Propargite (S-181) ................................................................................................................ 8085 

Propargyl alcohol .................................................................................................................. 8260 

Propazine .............................................................................................................................. 8085 

Propenal (Acrolein) ........................................................................8015, 8260, 8261, 8315, 8316 

Propetamidophos .................................................................................................................. 8085 

Propham ..................................................................................................................... 8141, 8321 

ß-Propiolactone ..................................................................................................................... 8260 

Propionaldehyde (Propanal).................................................................................................. 8315 

Propionitrile (Ethyl cyanide) .............................................................................. 8015, 8260, 8261 

Propoxur (Baygon) ...................................................................................................... 8318, 8321 

n-Propyl alcohol (1-Propanol) ...................................................................................... 8015, 8260 

n-Propylamine ....................................................................................................................... 8260 

n-Propylbenzene ............................................................................................... 8021, 8260, 8261 

Propylthiouracil ..................................................................................................................... 8270 

Prosulfocarb ................................................................................................................ 8141, 8321 

Prothiophos (Tokuthion) ........................................................................................................ 8141 

Pyrene ...........................................................................................8100, 8270, 8275, 8310, 8410 

Pyridine ............................................................................................................. 8015, 8260, 8261 

Ramrod (Propachlor)............................................................................................................. 8085 

RDX (Hexahydro-1,3,5-trinitro-1,3,5-triazine) .............................................................. 8095, 8330 

Resorcinol ............................................................................................................................. 8270 

Ronnel ........................................................................................................................ 8085, 8141 

Rotenone .............................................................................................................................. 8325 

S-181 (Propargite) ................................................................................................................ 8085 

Safrole .................................................................................................................................. 8270 

Sevin (Carbaryl) ...................................................................................... 8270, 8318, 8321, 8325 

Siduron ....................................................................................................................... 8321, 8325 

Simazine ..................................................................................................................... 8085, 8141 

Silvex (2,4,5-TP) ............................................................................................... 8085, 8151, 8321 

Solvent Red 3 ....................................................................................................................... 8321 

Solvent Red 23 ..................................................................................................................... 8321 

Sonalan (Ethalfluralin) ........................................................................................................... 8085 
SW-846 Update V TWO - 27 Revision 5 

July 2014

Stirophos (Tetrachlorvinphos, Gardona)............................................................ 8085, 8141, 8270 

Strobane ............................................................................................................................... 8081 

Strychnine ............................................................................................................................. 8270 

Styrene ............................................................................................................. 8021, 8260, 8261 

Sulfallate ............................................................................................................................... 8270 

Sulfotepp ..................................................................................................................... 8085, 8141 

Sulprofos (Bolstar) ...................................................................................................... 8085, 8141 

2,4,5-T ........................................................................................................................ 8151, 8321 

2,4,5-T (acid) ........................................................................................................................ 8085 

TAA (t-Amyl alcohol) ............................................................................................................. 8015 

TAEE (t-Amyl ethyl ether, 4,4-Dimethyl-3-oxahexane) ................................................ 8015, 8261 

TAME (t-Amyl methyl ether) ........................................................................................ 8015, 8261 

2,4,5-TB ................................................................................................................................ 8085 

2,3,7,8-TCDD .............................................................................................................. 8280, 8290 

TCDD, total ................................................................................................................. 8280, 8290 

2,3,7,8-TCDF .............................................................................................................. 8280, 8290 

TCDF, total ................................................................................................................. 8280, 8290 

Tebuthiuron ................................................................................................................. 8085, 8321 

Temephos (Abate) ................................................................................................................ 8085 

Temik (Aldicarb) .......................................................................................................... 8318, 8321 

TEPP (Tetraethyl pyrophosphate) ............................................................................... 8141, 8270 

Terbacil ................................................................................................................................. 8085 

Terbufos...................................................................................................................... 8141, 8270 

Terbutryn (Igran) ................................................................................................................... 8085 

1,2,3,4-Tetrachlorobenzene .................................................................................................. 8121 

1,2,3,5-Tetrachlorobenzene .................................................................................................. 8121 

1,2,4,5-Tetrachlorobenzene ........................................................................................ 8121, 8270 

2,2',3,5'-Tetrachlorobiphenyl ....................................................................................... 8082, 8275 

2,2',4,5'-Tetrachlorobiphenyl ................................................................................................. 8275 

2,2',5,5'-Tetrachlorobiphenyl ....................................................................................... 8082, 8275 

2,3',4,4'-Tetrachlorobiphenyl ....................................................................................... 8082, 8275 

1,1,1,2-Tetrachloroethane ........................................................................................... 8021, 8260 

1,1,2,2-Tetrachloroethane ................................................................................. 8021, 8260, 8261 

Tetrachloroethene (Perchloroethylene, Tetrachloroethylene) ............................ 8021, 8260, 8261 

2,3,4,5-Tetrachloronitrobenzene ........................................................................................... 8091 

2,3,5,6-Tetrachloronitrobenzene ........................................................................................... 8091 

2,3,4,5-Tetrachlorophenol ........................................................................................... 8041, 8085 

2,3,4,6-Tetrachlorophenol ................................................................................. 8041, 8085, 8270 

2,3,5,6-Tetrachlorophenol ..................................................................................................... 8041 

Tetrachlorvinphos (Stirophos, Gardona)............................................................ 8085, 8141, 8270 

Tetraethyl dithiopyrophosphate ............................................................................................. 8270 

Tetraethyl pyrophosphate (TEPP) ............................................................................... 8141, 8270 

Tetrahydrofuran (THF) .......................................................................................................... 8261 

Tetrazene .............................................................................................................................. 8331 

Tetryl (Methyl-2,4,6-trinitrophenylnitramine) .......................................................................... 8330 

THF (Tetrahydrofuran) .......................................................................................................... 8261 

Thiodicarb ................................................................................................................... 8318, 8321 

Thiofanox .............................................................................................................................. 8321 

Thionazin (Zinophos) .................................................................................................. 8141, 8270 

Thiophanate-methyl .............................................................................................................. 8321 

Thiophenol (Benzenethiol) .................................................................................................... 8270 
SW-846 Update V TWO - 28 Revision 5 

July 2014

1,3,5-TNB (1,3,5-Trinitrobenzene) ..................................................................... 8095, 8270, 8330 

2,4,6-TNT (2,4,6-Trinitrotoluene) ................................................................................. 8095, 8330 

TOCP (Tri-o-cresylphosphate) .............................................................................................. 8141 

Tokuthion (Prothiofos) ........................................................................................................... 8141 

m-Tolualdehyde .................................................................................................................... 8315 

o-Tolualdehyde ..................................................................................................................... 8315 

p-Tolualdehyde ..................................................................................................................... 8315 

Toluene ................................................................................................... 8015, 8021, 8260, 8261 

Toluene diisocyanate ............................................................................................................ 8270 

o-Toluidine .............................................................................................. 8015, 8260, 8261, 8270 

Toxaphene .............................................................................................. 8081, 8270, 8272, 8276 

2,4,5-TP (Silvex) ............................................................................................... 8085, 8151, 8321 

Treflan (Trifluralin) ................................................................................... 8081, 8085, 8091, 8270 

Triademefon .......................................................................................................................... 8085 

Triallate ............................................................................................................. 8085, 8141, 8321 

Tributyltin chloride ................................................................................................................. 8323 

Trichlorfon ................................................................................................................... 8141, 8321 

2,4,5-Trichloroaniline............................................................................................................. 8131 

2,4,6-Trichloroaniline............................................................................................................. 8131 

1,2,3-Trichlorobenzene ........................................................................... 8021, 8121, 8260, 8261 

1,2,4-Trichlorobenzene .............................................. 8021, 8121, 8260, 8261, 8270, 8275, 8410 

1,3,5-Trichlorobenzene ......................................................................................................... 8121 

2,2',5-Trichlorobiphenyl ............................................................................................... 8082, 8275 

2,3',5-Trichlorobiphenyl ......................................................................................................... 8275 

2,4',5-Trichlorobiphenyl ............................................................................................... 8082, 8275 

1,1,1-Trichloroethane ........................................................................................ 8021, 8260, 8261 

1,1,2-Trichloroethane ........................................................................................ 8021, 8260, 8261 

Trichloroethene (Trichloroethylene) ......................................................... 8021, 8260, 8261, 8535 

Trichlorofluoromethane ..................................................................................... 8021, 8260, 8261 

Trichloronate ......................................................................................................................... 8141 

1,2,3-Trichloro-4-nitrobenzene .............................................................................................. 8091 

1,2,4-Trichloro-5-nitrobenzene .............................................................................................. 8091 

2,4,6-Trichloronitrobenzene .................................................................................................. 8091 

2,3,4-Trichlorophenol ............................................................................................................ 8041 

2,3,5-Trichlorophenol ............................................................................................................ 8041 

2,3,6-Trichlorophenol ............................................................................................................ 8041 

2,4,5-Trichlorophenol .............................................................................. 8041, 8085, 8270, 8410 

2,4,6-Trichlorophenol .............................................................................. 8041, 8085, 8270, 8410 

2,3,4-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

2,3,5-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

2,3,6-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

2,4,5-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

2,4,6-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

3,4,5-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

1,2,3-Trichloropropane ...................................................................................... 8021, 8260, 8261 

Triclopyr (Garlon) .................................................................................................................. 8085 

Tri-o-cresylphosphate (TOCP) .............................................................................................. 8141 

O,O,O-Triethyl phosphorothioate .......................................................................................... 8270 

Triethylamine ........................................................................................................................ 8015 

Trifluralin (Treflan) ................................................................................... 8081, 8085, 8091, 8270 

Trihalomethanes ................................................................................................................... 8535 
SW-846 Update V TWO - 29 Revision 5 

July 2014

Trimethyl phosphate ............................................................................................................. 8270 

2,4,5-Trimethylaniline ............................................................................................................ 8270 

1,2,4-Trimethylbenzene .................................................................................... 8021, 8260, 8261 

1,3,5-Trimethylbenzene .................................................................................... 8021, 8260, 8261 

1,3,5-Trinitrobenzene (1,3,5-TNB)..................................................................... 8095, 8270, 8330 

2,4,6-Trinitrophenylmethylnitramine ...................................................................................... 8095 

2,4,6-Trinitrotoluene (2,4,6-TNT) ................................................................................. 8095, 8330 

Triphenyltin chloride .............................................................................................................. 8323 

Tris-BP (Tris(2,3-dibromopropyl) phosphate) .............................................................. 8270, 8321 

Tris(2,3-dibromopropyl) phosphate (Tris-BP) .............................................................. 8270, 8321 

Tri-p-tolyl phosphate ............................................................................................................. 8270 

Valeraldehyde (Pentanal) ...................................................................................................... 8315 

Vernolate .............................................................................................................................. 8085 

Vinyl acetate ......................................................................................................................... 8260 

Vinyl chloride .................................................................................................... 8021, 8260, 8261 

Vinylidene chloride (1,1-Dichloroethene) ........................................................... 8021, 8260, 8261 

m-Xylene ................................................................................................. 8015, 8021, 8260, 8261

o-Xylene.................................................................................................. 8015, 8021, 8260, 8261 

p-Xylene.................................................................................................. 8015, 8021, 8260, 8261 

Zinophos (Thionazin) .................................................................................................. 8141, 8270 

 
SW-846 Update V TWO - 30 Revision 5 

July 2014

TABLE 2-2 

 METHOD 8011 (MICROEXTRACTION AND GAS CHROMATOGRAPHY) 

1,2-Dibromo-3-chloropropane (DBCP) 

1,2-Dibromoethane (EDB) 

TABLE 2-3 

 METHOD 8015 (GC/FID) - NONHALOGENATED VOLATILES 

Acetone Ethylene oxide 

Acetonitrile Gasoline range organics (GRO) 

Acrolein Isopropyl alcohol 

Acrylonitrile Methanol 

Allyl alcohol Methyl ethyl ketone (MEK, 2-

Butanone) 

t-Amyl alcohol (TAA) N-Nitroso-di-n-butylamine 

t-Amyl ethyl ether (TAEE) Paraldehyde 

t-Amyl methyl ether (TAME) 2-Pentanone 

Benzene 2-Picoline 

t-Butyl alcohol 1-Propanol (n-Propyl alcohol) 

Crotonaldehyde Propionitrile 

Diesel range organics (DRO) Pyridine 

Diethyl ether Toluene 

Diisopropyl ether (DIPE) o-Toluidine 

Ethanol m-Xylene 

Ethyl acetate o-Xylene

Ethyl benzene p-Xylene 

 Ethyl tert-butyl ether (ETBE) Triethylamine 
SW-846 Update V TWO - 31 Revision 5 

July 2014

TABLE 2-4 

 METHOD 8021 (GC, PHOTOIONIZATION AND ELECTROLYTIC 

 CONDUCTIVITY DETECTORS) - AROMATIC AND HALOGENATED VOLATILES 

Allyl chloride cis-1,2-Dichloroethene 

Benzene trans-1,2-Dichloroethene 

Benzyl chloride 1,2-Dichloropropane 

Bis(2-chloro-1-methylethyl) ether 1,3-Dichloropropane 

Bromoacetone 2,2-Dichloropropane 

Bromobenzene 1,3-Dichloro-2-propanol 

Bromochloromethane 1,1-Dichloropropene 

Bromodichloromethane cis-1,3-Dichloropropene 

Bromoform trans-1,3-Dichloropropene 

Bromomethane Epichlorhydrin 

n-Butylbenzene Ethylbenzene 

sec-Butylbenzene Hexachlorobutadiene 

tert-Butylbenzene Isopropylbenzene 

Carbon tetrachloride p-Isopropyltoluene 

Chlorobenzene Methylene chloride 

Chlorodibromomethane Naphthalene 

Chloroethane n-Propylbenzene 

2-Chloroethanol Styrene 

2-Chloroethyl vinyl ether 1,1,1,2-Tetrachloroethane

Chloroform 1,1,2,2-Tetrachloroethane 

Chloromethane Tetrachloroethene 

Chloromethyl methyl ether Toluene 

Chloroprene 1,2,3-Trichlorobenzene 

2-Chlorotoluene 1,2,4-Trichlorobenzene 

4-Chlorotoluene 1,1,1-Trichloroethane 

1,2-Dibromo-3-chloropropane 1,1,2-Trichloroethane 

1,2-Dibromoethane Trichloroethene 

Dibromomethane Trichlorofluoromethane 

1,2-Dichlorobenzene 1,2,3-Trichloropropane 

1,3-Dichlorobenzene 1,2,4-Trimethylbenzene 

1,4-Dichlorobenzene 1,3,5-Trimethylbenzene 

Dichlorodifluoromethane Vinyl chloride 

1,1-Dichloroethane o-Xylene 

1,2-Dichloroethane m-Xylene 

1,1-Dichloroethene p-Xylene 

 
SW-846 Update V TWO - 32 Revision 5 

July 2014

TABLE 2-5 

 METHODS 8031 AND 8033 (GC WITH NITROGEN-PHOSPHORUS DETECTION) 

 AND METHOD 8032 (GC WITH ELECTRON CAPTURE DETECTION) 

Method 8031: Acrylonitrile 

Method 8032: Acrylamide 

Method 8033: Acetonitrile 

TABLE 2-6 

 METHOD 8041 (GC) - PHENOLS 

2-Chloro-5-methylphenol 2,5-Dinitrophenol 

4-Chloro-2-methylphenol Dinoseb (2-sec-butyl-4,6-dinitro phenol) 

4-Chloro-3-methylphenol 2-Methyl-4,6-dinitrophenol 

2-Chlorophenol 2-Methylphenol (o-Cresol) 

3-Chlorophenol 3-Methylphenol (m-Cresol) 

4-Chlorophenol 4-Methylphenol (p-Cresol) 

2-Cyclohexyl-4,6-dinitrophenol 2-Nitrophenol 

2,3-Dichlorophenol 3-Nitrophenol 

2,4-Dichlorophenol 4-Nitrophenol 

2,5-Dichlorophenol Pentachlorophenol 

2,6-Dichlorophenol Phenol 

3,4-Dichlorophenol 2,3,4,5-Tetrachlorophenol 

3,5-Dichlorophenol 2,3,4,6-Tetrachlorophenol 

2,3-Dimethylphenol 2,3,5,6-Tetrachlorophenol 

2,4-Dimethylphenol 2,3,4-Trichlorophenol 

2,5-Dimethylphenol 2,3,5-Trichlorophenol 

2,6-Dimethylphenol 2,3,6-Trichlorophenol 

3,4-Dimethylphenol 2,4,5-Trichlorophenol 

2,4-Dinitrophenol 2,4,6-Trichlorophenol 

 
SW-846 Update V TWO - 33 Revision 5 

July 2014

TABLE 2-7 

METHOD 8061 (GC/ECD) - PHTHALATE ESTERS 

Bis(2-n-butoxyethyl) phthalate Diethyl phthalate 

Bis(2-ethoxyethyl) phthalate Dihexyl phthalate 

Bis(2-ethylhexyl) phthalate Diisobutyl phthalate 

Bis(2-methoxyethyl) phthalate Di-n-butyl phthalate 

Bis(4-methyl-2-pentyl) phthalate Dimethyl phthalate 

Butyl benzyl phthalate Di-n-octyl phthalate 

Diamyl phthalate Dinonyl phthalate 

Dicyclohexyl phthalate Hexyl 2-ethylhexyl phthalate

TABLE 2-8 

METHOD 8070 (GC) - NITROSAMINES 

N-Nitrosodimethylamine 

N-Nitrosodiphenylamine 

N-Nitrosodi-n-propylamine 

 
SW-846 Update V TWO - 34 Revision 5 

July 2014

TABLE 2-9 

METHOD 8081 (GC) - ORGANOCHLORINE PESTICIDES 

Alachlor 4,4'-DDE Halowax-1051 

Aldrin 4,4'-DDT Halowax-1099 

α-BHC Diallate Heptachlor 

β-BHC Dichlone Heptachlor epoxide 

δ-BHC Dichloran Hexachlorobenzene 

γ-BHC (Lindane) Dicofol Hexachlorocyclopentadiene 

Captafol Dieldrin Isodrin 

Carbophenothion Endosulfan I Methoxychlor 

Chlordane (NOS) Endosulfan II Mirex 

cis-Chlordane Endosulfan sulfate Nitrofen 

trans-Chlordane Endrin trans-Nonachlor 

Chlorobenzilate Endrin aldehyde Pentachloronitrobenzene (PCNB) 

Chloroneb Endrin ketone Permethrin (cis + trans) 

Chloropropylate Etridiazole Perthane 

Chlorothalonil Halowax-1000 Propachlor 

Dacthal (DCPA) Halowax-1001 Strobane 

DBCP Halowax-1013 Toxaphene 

4,4'-DDD Halowax-1014 Trifluralin 
SW-846 Update V TWO - 35 Revision 5 

July 2014

TABLE 2-10 

METHOD 8082 (GC) - POLYCHLORINATED BIPHENYLS 

Aroclor 1016 2,2',3,4,5,5'-Hexachlorobiphenyl 

Aroclor 1221 2,2',3,5,5',6-Hexachlorobiphenyl 

Aroclor 1232 2,2',4,4',5,5'-Hexachlorobiphenyl 

Aroclor 1242 2,2',3,3',4,4',5,5',6-Nonachlorobiphenyl 

Aroclor 1248 2,2',3,4,5'-Pentachlorobiphenyl 

Aroclor 1254 2,2',4,5,5'-Pentachlorobiphenyl 

Aroclor 1260 2,3,3',4',6-Pentachlorobiphenyl 

2-Chlorobiphenyl 2,2',3,5'-Tetrachlorobiphenyl 

2,3-Dichlorobiphenyl 2,2',5,5'-Tetrachlorobiphenyl 

,2',3,3',4,4',5-Heptachlorobiphenyl 2,3',4,4'-Tetrachlorobiphenyl 

2,2',3,4,4',5,5'-Heptachlorobiphenyl 2,2',5-Trichlorobiphenyl 

2,2',3,4,4',5',6-Heptachlorobiphenyl 2,4',5-Trichlorobiphenyl 

2,2',3,4',5,5',6-Heptachlorobiphenyl 
SW-846 Update V TWO - 36 Revision 5 

July 2014

TABLE 2-11 

METHOD 8085 (GC/AED) – PESTICIDES 

Abate (Temephos) Cycloate Diphenamid 

Acifluorfen Coumaphos Disulfoton (Disyston) 

Alachlor 2,4-D acid Diuron 

Aldrin 2,4-DB acid Endosulfan I 

Ametryn DCPA (Dacthal) Endosulfan II 

Atraton 2,4'-DDD Endosulfan sulfate 

Atrazine 4,4'-DDD Endrin 

Azinphos ethyl (Ethyl guthion) 2,4'-DDE Endrin aldehyde 

Azinphos methyl (Guthion) 4,4'-DDE Endrin ketone 

Benfluralin 2,4'-DDT EPN 

α-BHC 4,4'-DDT Eptam (EPTC) 

β-BHC DEF (Butifos) Ethalfluralin (Sonalan) 

δ-BHC Demeton-O Ethion 

γ-BHC (Lindane) Demeton-S Ethoprop 

Bromacil Diallate Fenamiphos 

Bromoxynil (Brominal) Diazinon Fenarimol 

Butachlor Dicamba Fenitrothion 

Butylate Dichlobenil (Casoron) Fensulfothion 

Captafol 3,5-Dichlorobenzoic acid Fenthion 

Captan Dichlorprop Fluridone 

Carbophenothion Dichlorvos (DDVP) Fonofos 

Carboxin Diclofol (Kelthane) Gardona (Tetrachlovinphos) 

trans-Chlordane Diclofop-methyl Heptachlor 

Chlorpropham Dieldrin Heptachlor epoxide 

Chlorpyrifos Dimethoate Hexachlorobenzene 

Chlorthalonil (Daconil) Dinoseb Hexachlorocyclopentadiene 

Cyanazine Dioxathion Hexazinone 
SW-846 Update V TWO - 37 Revision 5 

July 2014

TABLE 2-11 (continued) 

Imidan (Phosmet) Norflurazon Sulfotepp 

Ioxynil Oxyfluorfen Sulprofos (Bolstar) 

Malathion Parathion Silvex 

MCPA acid Pebulate 2,4,5-T acid 

MCPP acid Pendimethalin 2,4,5-TB 

Merphos Pentachlorophenol (PCP) Tebuthiuron 

Metalaxyl Phorate Terbacil 

Methoxychlor Phosphamidon Terbutryn (Igran) 

Methyl chlorpyrifos Picloram 2,3,4,5-Tetrachlorophenol 

Methyl paraoxon Profluralin 2,3,4,6-Tetrachlorophenol 

Methyl parathion Prometon (Pramitol 5p) Triademefon

Metolachlor Prometryn Triallate 

Metribuzin Pronamide (Kerb) 2,4,5-Trichlorophenol 

Mevinphos Propachlor (Ramrod) 2,4,6-Trichlorophenol 

MGK-264 Propargite (S-181) Triclopyr (Garlon) 

Mirex Propazine Trifluralin (Treflan) 

Molinate Propetamidophos Vernolate 

Napropamide Ronnel 

4-Nitrophenol Simazine 

 
SW-846 Update V TWO - 38 Revision 5 

July 2014

TABLE 2-12 

METHOD 8091 (GC) - NITROAROMATICS AND CYCLIC KETONES 

Benefin 2,4-Dinitrotoluene 

Butralin 2,6-Dinitrotoluene 

1-Chloro-2,4-dinitrobenzene Isopropalin 

1-Chloro-3,4-dinitrobenzene 1,2-Naphthoquinone 

1-Chloro-2-nitrobenzene 1,4-Naphthoquinone 

1-Chloro-4-nitrobenzene Nitrobenzene 

2-Chloro-6-nitrotoluene 2-Nitrotoluene 

4-Chloro-2-nitrotoluene 3-Nitrotoluene 

4-Chloro-3-nitrotoluene 4-Nitrotoluene 

2,3-Dichloronitrobenzene Penoxalin [Pendimethalin] 

2,4-Dichloronitrobenzene Pentachloronitrobenzene 

2,5-Dichloronitrobenzene Profluralin 

3,4-Dichloronitrobenzene 2,3,4,5-Tetrachloronitrobenzene 

3,5-Dichloronitrobenzene 2,3,5,6-Tetrachloronitrobenzene 

Dinitramine 1,2,3-Trichloro-4-nitrobenzene 

1,2-Dinitrobenzene 1,2,4-Trichloro-5-nitrobenzene 

1,3-Dinitrobenzene 2,4,6-Trichloronitrobenzene 

1,4-Dinitrobenzene Trifluralin 

TABLE 2-13 

METHOD 8095 (GC) - EXPLOSIVES 

2-Amino-4,6-dinitrotoluene 2-Nitrotoluene 

4-Amino-2,6-dinitrotoluene 3-Nitrotoluene 

3,5-Dinitroaniline 4-Nitrotoluene 

1,3-Dinitrobenzene Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine 

2,4-Dinitrotoluene Pentaerythritoltetranitrate 

2,6-Dinitrotoluene 1,3,5-Trinitrobenzene 

Hexahydro-1,3,5-trinitro-1,3,5-triazine 2,4,6-Trinitrophenylmethylnitramine 

Nitrobenzene 2,4,6-Trinitrotoluene 

Nitroglycerine 
SW-846 Update V TWO - 39 Revision 5 

July 2014

TABLE 2-14 

METHOD 8100 - POLYNUCLEAR AROMATIC HYDROCARBONS 

Acenaphthene Dibenz(a,h)anthracene 

Acenaphthylene 7H-Dibenzo(c,g)carbazole 

Anthracene Dibenzo(a,e)pyrene 

Benz(a)anthracene Dibenzo(a,h)pyrene 

Benzo(b)fluoranthene Dibenzo(a,i)pyrene 

Benzo(j)fluoranthene Fluoranthene 

Benzo(k)fluoranthene Fluorene 

Benzo(g,h,i)perylene Indeno(1,2,3-cd)pyrene 

Benzo(a)pyrene 3-Methylcholanthrene 

Chrysene Naphthalene 

Dibenz(a,h)acridine Phenanthrene 

Dibenz(a,j)acridine Pyrene 

TABLE 2-15 

METHOD 8111 (GC) - HALOETHERS 

Bis(2-chloroethoxy)methane 2,5-Dichlorophenyl 4-nitrophenyl ether 

Bis(2-chloroethyl) ether 2,6-Dichlorophenyl 4-nitrophenyl ether 

Bis(2-chloro-1-methylethyl) ether 3,4-Dichlorophenyl 4-nitrophenyl ether 

4-Bromophenyl phenyl ether 3,5-Dichlorophenyl 4-nitrophenyl ether 

4-Chlorophenyl phenyl ether 4-Nitrophenyl phenyl ether 

2-Chlorophenyl 4-nitrophenyl ether 2,3,4-Trichlorophenyl 4-nitrophenyl ether 

3-Chlorophenyl 4-nitrophenyl ether 2,3,5-Trichlorophenyl 4-nitrophenyl ether 

4-Chlorophenyl 4-nitrophenyl ether 2,3,6-Trichlorophenyl 4-nitrophenyl ether 

2,4-Dibromophenyl 4-nitrophenyl ether 2,4,5-Trichlorophenyl 4-nitrophenyl ether 

2,4-Dichlorophenyl 3-methyl-4-nitrophenyl ether 2,4,6-Trichlorophenyl 4-nitrophenyl ether 

2,3-Dichlorophenyl 4-nitrophenyl ether 3,4,5-Trichlorophenyl 4-nitrophenyl ether 

2,4-Dichlorophenyl 4-nitrophenyl ether 
SW-846 Update V TWO - 40 Revision 5 

July 2014

TABLE 2-16 

METHOD 8121 (GC) - CHLORINATED HYDROCARBONS 

Benzal chloride δ-Hexachlorocyclohexane (δ-BHC) 

Benzotrichloride γ-Hexachlorocyclohexane (γ-BHC) 

Benzyl chloride Hexachlorocyclopentadiene 

2-Chloronaphthalene Hexachloroethane 

1,2-Dichlorobenzene Pentachlorobenzene 

1,3-Dichlorobenzene 1,2,3,4-Tetrachlorobenzene 

1,4-Dichlorobenzene 1,2,3,5-Tetrachlorobenzene 

Hexachlorobenzene 1,2,4,5-Tetrachlorobenzene 

Hexachlorobutadiene 1,2,3-Trichlorobenzene 

α-Hexachlorocyclohexane (α-BHC) 1,2,4-Trichlorobenzene 

β-Hexachlorocyclohexane (β-BHC) 1,3,5-Trichlorobenzene 

TABLE 2-17 

METHOD 8131 (GC) - ANILINE AND SELECTED DERIVATIVES

Aniline 2,6-Dibromo-4-nitroaniline 

4-Bromoaniline 3,4-Dichloroaniline 

2-Bromo-6-chloro-4-nitroanilne 2,6-Dichloro-4-nitroaniline 

2-Bromo-4,6-dintroaniline 2,4-Dinitroaniline 

2-Chloroaniline 2-Nitroaniline 

3-Chloroaniline 3-Nitroaniline 

4-Chloroaniline 4-Nitroaniline 

2-Chloro-4,6-dinitroaniline 2,4,5-Trichloroaniline 

2-Chloro-4-nitroaniline 2,4,6-Trichloroaniline 

4-Chloro-2-nitroaniline 
SW-846 Update V TWO - 41 Revision 5 

July 2014

TABLE 2-18 

METHOD 8141 (GC) - ORGANOPHOSPHORUS COMPOUNDS 

Aspon Disulfoton Parathion, methyl 

Atrazine EPN Pebulate 

Azinphos-ethyl EPTC o-Phenylenediamine 

Azinphos-methyl Ethion Phorate 

Bendiocarb Ethoprop Phosmet 

Bolstar (Sulprofos) Famphur Phosphamidon 

Butylate Fenitrothion Propham 

Carbophenothion Fensulfothion Prosulfocarb 

Chlorfenvinphos Fenthion Ronnel 

Chlorpyrifos Fonophos Simazine 

Chlorpyrifos methyl Hexamethyl phosphoramide 

(HMPA) 

Stirophos (Tetrachlorvinphos, 

Gardona) 

Coumaphos Leptophos Sulfotepp 

Crotoxyphos Malathion Terbufos 

Demeton-O, and -S Merphos Tetraethyl pyrophosphate (TEPP) 

Diazinon Methiocarb Thionazin (Zinophos) 

Dichlorofenthion Mevinphos Tokuthion (Prothiofos) 

Dichlorvos (DDVP) Molinate Triallate 

Dicrotophos Monocrotophos Trichlorfon 

Dimethoate Naled Trichloronate 

Dioxathion Parathion, ethyl Tri-o-cresyl phosphate (TOCP) 
SW-846 Update V TWO - 42 Revision 5 

July 2014

TABLE 2-19 

METHOD 8151 (GC USING METHYLATION OR PENTAFLUOROBENZYLATION 

DERIVATIZATION) - CHLORINATED HERBICIDES 

Acifluorfen Dicamba MCPP 

Bentazon 3,5-Dichlorobenzoic acid 4-Nitrophenol 

Chloramben Dichloroprop Pentachlorophenol 

2,4-D Dinoseb Picloram 

Dalapon 5-Hydroxydicamba 2,4,5-T 

2,4-DB MCPA 2,4,5-TP (Silvex) 

DCPA diacid 

 
SW-846 Update V TWO - 43 Revision 5 

July 2014

TABLE 2-20 

METHOD 8260 (GC/MS) - VOLATILE ORGANIC COMPOUNDS 

Acetone 2-Chloroethyl vinyl ether Diisopropyl ether (DIPE) 

Acetonitrile Chloroform 1,4-Dioxane 

Acrolein (Propenal) 1-Chlorohexane Epichlorohydrin 

Acrylonitrile Chloromethane Ethanol 

Allyl alcohol Chloroprene Ethyl acetate 

Allyl chloride 2-Chlorotoluene Ethyl t-butyl ether (ETBE) 

t-Amyl ethyl ether (TAEE) 4-Chlorotoluene Ethyl methacrylate 

t-Amyl methyl ether (TAME) Crotonaldehyde Ethylbenzene 

Benzene Cyclohexane Ethylene oxide 

Benzyl chloride 1,2-Dibromo-3-chloropropane Hexachlorobutadiene 

Bis(2-chloroethyl)sulfide 1,2-Dibromoethane Hexachloroethane 

Bromoacetone Dibromomethane 2-Hexanone 

Bromobenzene 1,2-Dichlorobenzene Iodomethane 

Bromochloromethane 1,3-Dichlorobenzene Isobutyl alcohol 

Bromodichloromethane 1,4-Dichlorobenzene Isopropylbenzene 

Bromoform cis-1,4-Dichloro-2-butene p-Isopropyltoluene 

Bromomethane trans-1,4-Dichloro-2-butene Malononitrile 

n-Butanol Dichlorodifluoromethane Methacrylonitrile

2-Butanone (MEK) 1,1-Dichloroethane Methanol 

t-Butyl alcohol 1,2-Dichloroethane Methyl acrylate 

n-Butylbenzene 1,1-Dichloroethene Methyl-t-butyl ether (MTBE) 

sec-Butylbenzene cis-1,2-Dichloroethene Methyl methacrylate 

tert-Butylbenzene trans-1,2-Dichloroethene Methylcyclohexane 

Carbon disulfide 1,2-Dichloropropane Methylene chloride 

Carbon tetrachloride 1,3-Dichloropropane 4-Methyl-2-pentanone (MIBK) 

Chloral hydrate 2,2-Dichloropropane Naphthalene 

Chloroacetonitrile 1,3-Dichloro-2-propanol Nitrobenzene 

Chlorobenzene 1,1-Dichloropropene 2-Nitropropane 

1-Chlorobutane cis-1,3-Dichloropropene N-Nitroso-di-n-butylamine 

Chlorodibromomethane trans-1,3-Dichloropropene Paraldehyde 

Chloroethane 1,2,3,4-Diepoxybutane Pentachloroethane 

2-Chloroethanol Diethyl ether Pentafluorobenzene 
SW-846 Update V TWO - 44 Revision 5 

July 2014

TABLE 2-20 (continued) 

2-Pentanone Styrene Trichloroethene 

2-Picoline 1,1,1,2-Tetrachloroethane Trichlorofluoromethane 

1-Propanol 1,1,2,2-Tetrachloroethane 1,2,3-Trichloropropane 

2-Propanol Tetrachloroethene 1,2,4-Trimethylbenzene

Propargyl alcohol Toluene 1,3,5-Trimethylbenzene 

ß-Propiolactone o-Toluidine Vinyl acetate 

Propionitrile (Ethyl cyanide) 1,2,3-Trichlorobenzene Vinyl chloride 

n-Propylamine 1,2,4-Trichlorobenzene o-Xylene 

n-Propylbenzene 1,1,1-Trichloroethane m-Xylene 

Pyridine 1,1,2-Trichloroethane p-Xylene 

 
SW-846 Update V TWO - 45 Revision 5 

July 2014

TABLE 2-21 

METHOD 8261 (VD/GC/MS) - VOLATILE ORGANIC COMPOUNDS

Acetone 1,3-Dichlorobenzene Methacrylonitrile 

Acetonitrile 1,4-Dichlorobenzene Methyl t-butyl ether (MTBE) 

Acetophenone cis-1,4-Dichloro-2-butene Methyl methacrylate 

Acrolein trans-1,4-Dichloro-2-butene Methylene chloride 

Acrylonitrile Dichlorodifluoromethane 1-Methylnaphthalene 

Allyl Chloride 1,1-Dichloroethane 2-Methylnaphthalene 

t-Amyl ethyl ether (TAEE) 

(4,4-Dimethyl-3-oxahexane) 

1,2-Dichloroethane 4-Methyl-2-pentanone 

t-Amyl methyl ether (TAME) 1,1-Dichloroethene Naphthalene 

Aniline cis-1,2-Dichloroethene N-Nitrosodibutylamine 

Benzene trans-1,2-Dichloroethene N-Nitrosodiethylamine

Bromochloromethane 1,2-Dichloropropane N-Nitrosodimethylamine 

Bromodichloromethane 1,3-Dichloropropane N-Nitrosodi-n-propylamine 

Bromoform 2,2-Dichloropropane N-Nitrosomethylethylamine

Bromomethane 1,1-Dichloropropene Pentachloroethane 

2-Butanone cis-1,3-Dichloropropene 2-Picoline 

n-Butylbenzene trans-1,3-Dichloropropene Propionitrile 

sec-Butylbenzene Diethyl ether n-Propylbenzene 

tert-Butylbenzene Diisopropyl ether (DIPE) Pyridine 

Carbon disulfide 1,4-Dioxane Styrene 

Carbon tetrachloride Ethanol 1,1,2,2-Tetrachloroethane 

Chlorobenzene Ethyl acetate Tetrachloroethene 

Chlorodibromomethane Ethyl t-butyl ether (ETBE) Tetrahydrofuran 

Chloroethane Ethyl methacrylate Toluene 

Chloroform Ethylbenzene o-Toluidine 

Chloromethane Hexachlorobutadiene 1,2,3-Trichlorobenzene 

2-Chlorotoluene 2-Hexanone 1,2,4-Trichlorobenzene 

4-Chlorotoluene Iodomethane 1,1,1-Trichloroethane 

1,2-Dibromo-3-chloropropane Isobutyl alcohol 1,1,2-Trichloroethane 

Dibromomethane Isopropylbenzene Trichloroethene 

1,2-Dichlorobenzene p-Isopropyltoluene Trichlorofluoromethane 
SW-846 Update V TWO - 46 Revision 5 

July 2014

TABLE 2-21 (continued) 

1,2,3-Trichloropropane Vinyl chloride p-Xylene 

1,2,4-Trimethylbenzene o-Xylene 

1,3,5-Trimethylbenzene m-Xylene 

TABLE 2-22 

METHOD 8270 (GC/MS) - SEMIVOLATILE ORGANIC COMPOUNDS 

Acenaphthene Aroclor-1260 

Acenaphthylene Azinphos-methyl 

Acetophenone Barban 

2-Acetylaminofluorene Benz(a)anthracene 

1-Acetyl-2-thiourea Benzidine 

Aldrin Benzo(b)fluoranthene 

2-Aminoanthraquinone Benzo(k)fluoranthene 

Aminoazobenzene Benzoic acid 

4-Aminobiphenyl Benzo(g,h,i)perylene 

3-Amino-9-ethylcarbazole Benzo(a)pyrene 

Anilazine p-Benzoquinone 

Aniline Benzyl alcohol 

o-Anisidine α-BHC 

Anthracene β-BHC 

Aramite δ-BHC 

Aroclor-1016 γ-BHC (Lindane) 

Aroclor-1221 Bis(2-chloroethoxy)methane 

Aroclor-1232 Bis(2-chloroethyl)ether 

Aroclor-1242 Bis(2-chloro-1-methylethyl)ether 

Aroclor-1248 Bis(2-ethylhexyl)phthalate 

Aroclor-1254 4-Bromophenyl phenyl ether 
SW-846 Update V TWO - 47 Revision 5 

July 2014

Table 2-22 (continued) 

Bromoxynil Demeton-S 

Butyl benzyl phthalate Diallate (cis or trans) 

Captafol 2,4-Diaminotoluene 

Captan Dibenz(a,j)acridine 

Carbaryl Dibenz(a,h)anthracene 

Carbofuran Dibenzofuran 

Carbophenothion Dibenzo(a,e)pyrene 

Chlordane (NOS) 1,2-Dibromo-3-chloropropane 

Chlorfenvinphos Di-n-butyl phthalate 

4-Chloroaniline Dichlone 

Chlorobenzilate 1,2-Dichlorobenzene 

5-Chloro-2-methylaniline 1,3-Dichlorobenzene 

4-Chloro-3-methylphenol 1,4-Dichlorobenzene 

3-(Chloromethyl)pyridine hydrochloride 3,3'-Dichlorobenzidine 

1-Chloronaphthalene 2,4-Dichlorophenol 

2-Chloronaphthalene 2,6-Dichlorophenol 

2-Chlorophenol Dichlorovos 

4-Chloro-1,2-phenylenediamine Dicrotophos 

4-Chloro-1,3-phenylenediamine Dieldrin 

4-Chlorophenyl phenyl ether Diethyl phthalate 

Chrysene Diethyl sulfate 

Coumaphos Diethylstilbestrol 

p-Cresidine Dimethoate 

Crotoxyphos 3,3'-Dimethoxybenzidine 

2-Cyclohexyl-4,6-dinitrophenol Dimethyl phthalate 

4,4'-DDD Dimethylaminoazobenzene 

4,4'-DDE 7,12-Dimethylbenz(a)anthracene 

4,4'-DDT 3,3'-Dimethylbenzidine 

Demeton-O α,α-Dimethylphenethylamine 
SW-846 Update V TWO - 48 Revision 5 

July 2014

Table 2-22 (continued) 

2,4-Dimethylphenol Fluchloralin 

1,2-Dinitrobenzene Fluoranthene 

1,3-Dinitrobenzene Fluorene 

1,4-Dinitrobenzene Heptachlor 

4,6-Dinitro-2-methylphenol Heptachlor epoxide 

2,4-Dinitrophenol Hexachlorobenzene 

2,4-Dinitrotoluene Hexachlorobutadiene 

2,6-Dinitrotoluene Hexachlorocyclopentadiene 

Dinocap Hexachloroethane 

Dinoseb Hexachlorophene 

Di-n-octyl phthalate Hexachloropropene 

Diphenylamine Hexamethylphosphoramide 

5,5-Diphenylhydantoin Hydroquinone 

1,2-Diphenylhydrazine Indeno(1,2,3-cd)pyrene 

Disulfoton Isodrin 

Endosulfan I Isophorone 

Endosulfan II Isosafrole 

Endosulfan sulfate Kepone 

Endrin Leptophos 

Endrin aldehyde Malathion 

Endrin ketone Maleic anhydride 

EPN Mestranol 

Ethion Methapyrilene 

Ethyl carbamate Methoxychlor 

Ethyl methanesulfonate Methyl methanesulfonate 

Famphur Methyl parathion 

Fensulfothion 3-Methylcholanthrene 

Fenthion 4,4'-Methylenebis(2-chloroaniline) 
SW-846 Update V TWO - 49 Revision 5 

July 2014

Table 2-22 (continued) 

4,4'-Methylenebis(N,N-dimethylaniline) N-Nitrosodimethylamine 

2-Methylnaphthalene N-Nitrosodiphenylamine 

2-Methylphenol N-Nitrosodi-n-propylamine 

3-Methylphenol N-Nitrosomethylethylamine 

4-Methylphenol N-Nitrosomorpholine 

Mevinphos N-Nitrosopiperidine 

Mexacarbate N-Nitrosopyrrolidine 

Mirex 5-Nitro-o-toluidine 

Monocrotophos Octamethyl pyrophosphoramide 

Naled 4,4'-Oxydianiline 

Naphthalene Parathion 

1,4-Naphthoquinone Pentachlorobenzene 

1-Naphthylamine Pentachloronitrobenzene 

2-Naphthylamine Pentachlorophenol 

Nicotine Phenacetin 

5-Nitroacenaphthene Phenanthrene 

2-Nitroaniline Phenobarbital 

3-Nitroaniline Phenol 

4-Nitroaniline 1,4-Phenylenediamine 

5-Nitro-o-anisidine Phorate 

Nitrobenzene Phosalone 

4-Nitrobiphenyl Phosmet 

Nitrofen Phosphamidion 

2-Nitrophenol Phthalic anhydride 

4-Nitrophenol 2-Picoline (2-methylpyridine) 

Nitroquinoline-1-oxide Piperonyl sulfoxide 

N-Nitrosodi-n-butylamine Pronamide 

N-Nitrosodiethylamine Propylthiouracil 
SW-846 Update V TWO - 50 Revision 5 

July 2014

Table 2-22 (continued) 

Pyrene Toluene diisocyanate 

Resorcinol o-Toluidine 

Safrole Toxaphene 

Strychnine 1,2,4-Trichlorobenzene 

Sulfallate 2,4,5-Trichlorophenol 

Terbufos 2,4,6-Trichlorophenol 

1,2,4,5-Tetrachlorobenzene O,O,O-Triethylphosphorothioate 

2,3,4,6-Tetrachlorophenol Trifluralin 

Tetrachlorvinphos Trimethyl phosphate 

Tetraethyl dithiopyrophosphate 2,4,5-Trimethylaniline 

Tetraethyl pyrophosphate 1,3,5-Trinitrobenzene 

Thionazine Tris(2,3-dibromopropyl)phosphate 

Thiophenol (Benzenethiol) Tri-p-tolyl phosphate 

 
SW-846 Update V TWO - 51 Revision 5 

July 2014

TABLE 2-23 

METHOD 8275 (TE/GC/MS) - SEMIVOLATILE ORGANIC COMPOUNDS 

Acenaphthene 2,2',3,4',5,5',6- Heptachlorobiphenyl 

Acenaphthylene Hexachlorobenzene 

Anthracene 2,2',3,3',4,4'- Hexachlorobiphenyl 

Benz(a)anthracene 2,2',3,4,4',5'- Hexachlorobiphenyl 

Benzo(k)fluoranthene Indeno(1,2,3-cd)pyrene 

Benzo(b)fluoranthene Naphthalene 

Benzo(g,h,i)perylene 2,2',3,3'4,4',5,5',6- Nonachlorobiphenyl 

Benzo(a)pyrene 2,2',3,3',4,4',5,5'- Octachlorobiphenyl 

4-Bromophenyl phenyl ether 2,2',4,5,5'-Pentachlorobiphenyl 

2-Chlorobiphenyl 2,3',4,4',5-Pentachlorobiphenyl 

1-Chloronaphthalene Phenanthrene 

Chrysene Pyrene 

2,2',3,3'4,4',5,5',6,6'- Decachlorobiphenyl 2,2'3,5'-Tetrachlorobiphenyl 

Dibenz(a,h)anthracene 2,2'4,5'-Tetrachlorobiphenyl 

Dibenzofuran 2,2',5,5'-Tetrachlorobiphenyl 

Dibenzothiophene 2,3',4,4'-Tetrachlorobiphenyl 

3,3'-Dichlorobiphenyl 1,2,4-Trichlorobenzene 

Fluoranthene 2,2',5-Trichlorobiphenyl 

Fluorene 2,3',5-Trichlorobiphenyl 

2,2',3,3',4,4',5- Heptachlorobiphenyl 2,4',5-Trichlorobiphenyl 

2,2',3,4,4',5,5'- Heptachlorobiphenyl 

 
SW-846 Update V TWO - 52 Revision 5 

July 2014

TABLE 2-23A 

METHOD 8276 (GC-NICI/MS) - TOXAPHENE AND TOXAPHENE CONGENERS 

2-endo,3-exo,5-endo,6-exo,8,9,10-Heptachlorobornane (Hp-Sed) 

2-exo,3-endo,6-exo,8,9,10-Hexachlorobornane (Hx-Sed)

2,2,5,5,8,9,9,10,10-Nonachlorobornane (P62)

2-endo,3-exo,5-endo,6-exo,8,8,9,10,10-Nonachlorobornane (P50) 

2-endo,3-exo,5-endo,6-exo,8,8,10,10-Octachlorobornane (P26) 

2-endo,3-exo,5-endo,6-exo,8,9,10,10-Octachlorobornane (P40) 

2-exo,3-endo,5-exo,8,9,9,10,10-Octachlorobornane (P41)

2-exo,5,5,8,9,9,10,10-Octachlorobornane (P44) 

Toxaphene 

TABLE 2-24 

METHODS 8280 (HRGC/LRMS) AND 8290 (HRGC/HRMS) - POLYCHLORINATED DIBENZOp-DIOXINS (PCDDs) AND POLYCHLORINATED DIBENZOFURANS (PCDFs) 

1,2,3,4,6,7,8-HpCDD 2,3,4,6,7,8-HxCDF 

HpCDD, total HxCDF, total 

1,2,3,4,6,7,8-HpCDF OCDD 

1,2,3,4,7,8,9-HpCDF OCDF TCDF, total 

HpCDF, total 1,2,3,7,8-PeCDD 

1,2,3,4,7,8-HxCDD PeCDD, total 

1,2,3,6,7,8-HxCDD 1,2,3,7,8-PeCDF 

1,2,3,7,8,9-HxCDD 2,3,4,7,8-PeCDF 

HxCDD, total PeCDF, total 

1,2,3,4,7,8-HxCDF 2,3,7,8-TCDD 

1,2,3,6,7,8-HxCDF TCDD, total 

1,2,3,7,8,9-HxCDF 2,3,7,8-TCDF 
SW-846 Update V TWO - 53 Revision 5 

July 2014

TABLE 2-25 

METHOD 8310 (HPLC) - POLYNUCLEAR AROMATIC HYDROCARBONS 

Acenaphthene Chrysene 

Acenaphthylene Dibenzo(a,h)anthracene 

Anthracene Fluoranthene 

Benz(a)anthracene Fluorene 

Benzo(b)fluoranthene Indeno(1,2,3-cd)pyrene 

Benzo(k)fluoranthene Naphthalene 

Benzo(g,h,i)perylene Phenanthrene 

Benzo(a)pyrene Pyrene 

TABLE 2-26 

METHOD 8315 - CARBONYL COMPOUNDS 

Acetaldehyde Decanal Octanal 

Acetone 2,5-Dimethylbenzaldehyde Pentanal (Valeraldehyde) 

Acrolein Formaldehyde Propanal (Propionaldehyde) 

Benzaldehyde Heptanal m-Tolualdehyde 

Butanal (Butyraldehyde) Hexanal (Hexaldehyde) o-Tolualdehyde 

Crotonaldehyde Isovaleraldehyde p-Tolualdehyde 

Cyclohexanone Nonanal 

 
SW-846 Update V TWO - 54 Revision 5 

July 2014

TABLE 2-27 

METHOD 8316 (HPLC) 

Acrolein 

Acrylamide 

Acrylonitrile 

TABLE 2-28 

METHOD 8318 (HPLC) - N-METHYLCARBAMATES 

Aldicarb (Temik) Dioxacarb Mexacarbate 

Aldicarb sulfone Formetanate hydrochloride Oxamyl 

Bendiocarb 3-Hydroxycarbofuran Promecarb 

Carbaryl (Sevin) Methiocarb (Mesurol) Propoxur (Baygon) 

Carbofuran (Furadan) Methomyl (Lannate) Thiodicarb 

m-Cumenyl methylcarbamate Metolcarb 
SW-846 Update V TWO - 55 Revision 5 

July 2014

TABLE 2-29 

METHOD 8321 (HPLC/TS/MS) - NONVOLATILE ORGANIC COMPOUNDS 

Azo Dyes Organophosphorus Compounds 

Disperse Brown 1 Asulam 

Disperse Orange 3 Dichlorvos (DDVP) 

Disperse Orange 30 Dimethoate 

Disperse Red 1 Disulfoton 

Disperse Red 5 Famphur 

Disperse Red 13 Fensulfothion 

Disperse Yellow 5 Merphos 

Solvent Red 3 Methomyl 

Solvent Red 23 Monocrotophos 

Naled 

Anthraquinone Dyes Parathion methyl 

Disperse Blue 3 Phorate 

Disperse Blue 14 Thiofanox 

Disperse Red 60 Trichlorfon 

Tris(2,3-dibromopropyl) phosphate (Tris-BP) 

Chlorinated Phenoxyacid Compounds 

2,4-D Silvex (2,4,5-TP) 

2,4-D, butoxyethanol ester 2,4,5-T 

2,4-D, ethylhexyl ester 2,4,5-T, butyl ester 

Dalapon 2,4,5-T, butoxyethanol ester 

2,4-DB 

Dicamba 

Dichlorprop 

Dinoseb 

MCPA 

MCPP 
SW-846 Update V TWO - 56 Revision 5 

July 2014

Table 2-29 (continued) 

Carbamates 

Aldicarb Linuron 

Aldicarb sulfone Methiocarb 

Aldicarb sulfoxide Methomyl 

Aminocarb Metolcarb 

Barban Mexacarbate 

Bendiocarb Molinate 

Benomyl Monuron 

Bromacil Neburon 

Butylate Oxamyl 

Carbaryl Pebulate

Carbendazim o-Phenylenediamine 

Carbofuran Physostigmine 

Carbofuran phenol Physostigmine salicylate 

Carbosulfan Promecarb 

Chloropropham Propham 

Chloroxuron Propoxur 

m-Cumenyl methyl carbamate Prosulfocarb 

Diuron Siduron 

EPTC Tebuthiuron 

Fenuron Thiodicarb 

Fluometuron Thiophanate-methyl 

Formetanate hydrochloride Triallate 

3-Hydroxycarbofuran 

 
SW-846 Update V TWO - 57 Revision 5 

July 2014

TABLE 2-29A 

METHOD 8323 (MS) - ORGANOTINS BY MICRO-LIQUID CHROMATOGRAPHYELECTROSPRAY ION TRAP MASS SPECTROMETRY 

Dibutyltin dichloride Monophenyltin trichloride 

Diphenyltin dichloride Tributyltin chloride

Monobutyltin trichloride Triphenyltin chloride 

TABLE 2-30 

METHOD 8325 (HPLC/PB/MS) - NONVOLATILE ORGANIC COMPOUNDS 

Benzidine 3,3'-Dimethylbenzidine 

Benzoylprop ethyl Diuron 

Carbaryl Linuron (Lorox) 

o-Chlorophenyl thiourea Monuron 

3,3'-Dichlorobenzidine Rotenone 

3,3'-Dimethoxybenzidine Siduron 

TABLE 2-31 

METHOD 8330 (HPLC) - NITROAROMATICS AND NITRAMINES 

2-Amino-4,6-dinitrotoluene (2-Am-DNT) 2-Nitrotoluene (2-NT) 

4-Amino-2,6-dinitrotoluene (4-Am-DNT) 3-Nitrotoluene (3-NT) 

3,5-Dinitroanaline (3,5-DNA) 4-Nitrotoluene (4-NT) 

1,3-Dinitrobenzene (1,3-DNB) Nitroglycerin 

2,4-Dinitrotoluene (2,4-DNT) Octahydro-1,3,5,7-tetranitro-1,3,5,7- 

tetrazocine (HMX) 

2,6-Dinitrotoluene (2,6-DNT) Pentaerythritol tetranitrate (PETN) 

Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) 1,3,5-Trinitrobenzene (1,3,5-TNB) 

Methyl-2,4,6-trinitrophenyl-nitramine (Tetryl) 2,4,6-Trinitrotoluene (2,4,6-TNT) 

Nitrobenzene (NB) 
SW-846 Update V TWO - 58 Revision 5 

July 2014

TABLE 2-32 

METHOD 8331 (HPLC) 

Tetrazene 

TABLE 2-33 

METHOD 8332 (HPLC) 

Nitroglycerine 

TABLE 2-34 

METHOD 8410 - SEMIVOLATILE ORGANIC COMPOUNDS 

Acenaphthene 1,2-Dichlorobenzene 

Acenaphthylene 1,3-Dichlorobenzene 

Anthracene 1,4-Dichlorobenzene 

Benzo(a)anthracene 2,4-Dichlorophenol 

Benzo(a)pyrene Diethyl phthalate 

Benzoic acid Dimethyl phthalate 

Bis(2-chloroethoxy)methane 4,6-Dinitro-2-methylphenol 

Bis(2-chloroethyl)ether 2,4-Dinitrophenol 

Bis(2-chloro-1-methylethyl)ether 2,4-Dinitrotoluene

Bis(2-ethylhexyl) phthalate 2,6-Dinitrotoluene 

4-Bromophenyl phenyl ether Di-n-octyl phthalate 

Butyl benzyl phthalate Di-n-propyl phthalate 

4-Chloroaniline Fluoranthene 

4-Chloro-3-methylphenol Fluorene 

2-Chloronaphthalene Hexachlorobenzene 

2-Chlorophenol 1,3-Hexachlorobutadiene 

4-Chlorophenol Hexachlorocyclopentadiene 

4-Chlorophenyl phenyl ether Hexachloroethane 

Chrysene Isophorone 

Dibenzofuran 2-Methylnaphthalene 

Di-n-butyl phthalate 2-Methylphenol
SW-846 Update V TWO - 59 Revision 5 

July 2014

Table 2-34 (continued) 

4-Methylphenol N-Nitrosodiphenylamine 

Naphthalene N-Nitroso-di-n-propylamine 

2-Nitroaniline Pentachlorophenol 

3-Nitroaniline Phenanthrene 

4-Nitroaniline Phenol 

Pyrene 

2-Nitrophenol 1,2,4-Trichlorobenzene 

4-Nitrophenol 2,4,5-Trichlorophenol 

N-Nitrosodimethylamine 2,4,6-Trichlorophenol 

TABLE 2-35 

METHOD 8430 (GC/FT-IR) - BIS(2-CHLOROETHYL) ETHER AND ITS HYDROLYSIS 

PRODUCTS 

Bis(2-chloroethyl) ether 

2-Chloroethanol 

2-(2-Chloroethoxy) ethanol 

Diethylene glycol 

Ethylene glycol 

TABLE 2-35A 

METHOD 8440 - TOTAL RECOVERABLE PETROLEUM HYDROCARBONS BY INFRARED 

SPECTROPHOTOMETRY 

This method does not give a specific compound list but is applicable to total recoverable 

petroleum hydrocarbons. 
SW-846 Update V TWO - 60 Revision 5 

July 2014

TABLE 2-36 

METHOD 8510 (COLORIMETRIC SCREENING) - RDX AND HMX 

Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) 

Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) 

TABLE 2-36A 

METHOD 8520 (CONTINUOUS MEASUREMENT OF FORMALDEHYDE IN AMBIENT AIR) 

Formaldehyde 

TABLE 2-37 

METHOD 8535 (COLORIMETRIC SCREENING) - VOLATILE ORGANIC HALIDES 

Carbon tetrachloride 

Perchloroethylene (Tetrachloroethene) 

Trichloroethylene 

Trihalomethanes 

TABLE 2-38 

METHOD 8540 (UV-INDUCED COLORIMETRY) - PENTACHLOROPHENOL 

Pentachlorophenol 

 
SW-846 Update V TWO - 61 Revision 5 

July 2014

TABLE 2-39 

DETERMINATIVE METHODS FOR INORGANIC ANALYTES 

Analyte Applicable Methods 

Aluminum ............................................................................................... 6010, 6020, 7000, 7010 

Antimony .............................................................................. 6010, 6020, 6200, 6800, 7000, 7062 

Arsenic ....................................................................... 6010, 6020, 6200, 7010, 7061, 7062, 7063 

Barium ................................................................................. 6010, 6020, 6200, 6800, 7000, 7010 

Beryllium ................................................................................................. 6010, 6020, 7000, 7010 

Boron .......................................................................................................................... 6010, 6800 

Bromide ............................................................................................................ 6500, 9056, 9211 

Cadmium ............................................................................. 6010, 6020, 6200, 6800, 7000, 7010 

Calcium ..........................................................................................6010, 6020, 6200, 6800, 7000 

Chloride ..................................................................... 6500, 9056, 9057, 9212, 9250, 9251, 9253 

Chromium ............................................................................ 6010, 6020, 6200, 6800, 7000, 7010 

Chromium, hexavalent ......................................................... 6800, 7195, 7196, 7197, 7198, 7199 

Cobalt ............................................................................................6010, 6020, 6200, 7000, 7010 

Copper ................................................................................. 6010, 6020, 6200, 6800, 7000, 7010 

Cyanide...................................................................... 9010, 9012, 9013, 9014, 9015, 9016, 9213 

Fluoride ............................................................................................................. 6500, 9056, 9214 

Iron ...................................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Lead ..................................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Lithium ........................................................................................................................ 6010, 7000 

Magnesium ............................................................................................. 6010, 6020, 6800, 7000 

Manganese ....................................................................................6010, 6020, 6200, 7000, 7010 

Mercury ................................................. 6010, 6020, 6200, 6800, 7470, 7471, 7472, 7473, 7474 

Molybdenum ..................................................................................6010, 6200, 6800, 7000, 7010 

Nickel ................................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Nitrate ............................................................................................................... 6500, 9056, 9210 

Nitrite ................................................................................................................ 6500, 9056, 9216 

Osmium ................................................................................................................................ 7000 

Perchlorate ................................................................................................................. 6850, 6860 

Phosphate ................................................................................................................... 6500, 9056 

Phosphorus ........................................................................................................................... 6010 

Phosphorus, white ................................................................................................................ 7580 

Potassium ......................................................................................6010, 6020, 6200, 6800, 7000 

Rubidium ............................................................................................................................... 6200 

Selenium .................................................................... 6010, 6020, 6200, 6800, 7010, 7741, 7742 

Silica ..................................................................................................................................... 6010 

Silver .................................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Sodium ............................................................................................................. 6010, 6020, 7000 

Strontium ................................................................................................ 6010, 6200, 6800, 7000 

Sulfate ...........................................................................................6500, 9035, 9036, 9038, 9056 

Sulfide ............................................................................................................... 9030, 9031, 9215 

Thallium ............................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Thorium................................................................................................................................. 6200 

Tin ..................................................................................................................... 6010, 6200, 7000 

Titanium ...................................................................................................................... 6010, 6200 
SW-846 Update V TWO - 62 Revision 5 

July 2014

TABLE 2-39 (cont) 

Vanadium ............................................................................. 6010, 6020, 6200, 6800, 7000, 7010 

Zinc ...................................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Zirconium .............................................................................................................................. 6200 
 SW-846 Update V TWO - 63 

 

TABLE 2-40A 

RECOMMENDED SAMPLE CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING TIMES FOR ORG

(Note: Footnotes are located on the last page of the table.) 

VOLATILE ORGANICS

Sample Matrix Container Preservative1 Concentrated waste samples 

Method 5035: See the method. Method 5021: See the method. Methods 5031 and 5032: See the methods. Use PTFE-lined lids for all procedures. 

Cool to 0 - 6 °C. 

Aqueous samples with no 

residual chlorine present 

Methods 5030, 5031, and 5032: 3 x 40-mL vials with PTFE-lined septum caps 

Cool to 0 - 6 °C and adjust pH to less than 2 with H2SO4, HCl, or solid NaHSO4

If carbonaceous materials are present, or if MTBE and other fuel oxygenate ethers are 

present and a high temperature sample preparative method is to be used, do not acid preserve the samples. 

If the reactive compound 2-chloroethyl vinyl etherb is an analyte of interest, collect a 

second set of samples without acid 

preservatives and analyze immediately. 
TABLE 2-40A (continued) 

RECOMMENDED SAMPLE CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING TIMES FOR ORGANI

 SW-846 Update V TWO - 64 

 

VOLATILE ORGANICS (continued)

Sample Matrix Container Preservative1 

Aqueous samples WITH 

residual chlorine present 

Methods 5030, 5031, and 5032: 3 x 40-mL vials with PTFE-lined septum caps 

Collect sample in a 125-mL container which has been pre-preserved with 4 drops of 10% sodium thiosulfate solution. Gently swirl to mix sample and transfer to a 40-mL VOA vial. Cool to 0 - 6 °C and adjust pH to less than 2 

with H2SO4, HCl, or solid NaHSO4. If carbonaceous materials are present, or if 

MTBE and other fuel oxygenate ethers are 

present and a high temperature sample preparative method is to be used, do not acid preserve the samples. 

If the reactive compound 2-chloroethyl vinyl etherb is an analyte of interest, collect a 

second set of samples without acid 

preservatives and analyze immediately.

Acrolein and acrylonitrile 

in aqueous samples 

Methods 5030, 5031, and 5032: 3 x 40-mL vials with PTFE-lined septum caps 

Adjust to pH 4-5. Cool to 0 - 6 °C. 

These compounds are highly reactive and should be analyzed as soon as possible.

Solid samples (e.g., soils, sediments, sludges, ash) 

Method 5035: See the method. Method 5021: See the method. Methods 5031 and 5032: See the methods. 

See the individual methods. If vinyl chloride, styrene, or 2-chloroethyl vinyl ether are analytes of interest, collect a second set of samples without acid preservatives and analyze as soon as possible.
TABLE 2-40A (continued) 

RECOMMENDED SAMPLE CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING TIMES FOR ORGANI

 SW-846 Update V TWO - 65 

 

SEMIVOLATILE ORGANICS/ORGANOCHLORINE PESTICIDES AND HERBICIDES 

Sample Matrix Container Preservative1 Concentrated waste samples 

125-mL wide-mouth glass with PTFE-lined lid 

None 

Aqueous samples with no 

residual chlorine present 

4 x 1-L amber glass container with PTFElined lid, or other size, as appropriate, to allow use of entire sample for analysis. 

Cool to 0 - 6 °C. 

Aqueous samples WITH 

residual chlorine present 

4 x 1-L amber glass container with PTFElined lid, or other size, as appropriate, to allow use of entire sample for analysis. 

Add 3 mL 10% sodium thiosulfate solution per 

gallon (or 0.008%). Addition of sodium thiosulfate solution to sample container may be performed in the laboratory prior to field use. Cool to 0 - 6 °C. 

Solid samples (e.g., soils, sediments, sludges, ash) 

250-mL wide-mouth glass container with PTFE-lined lid 

Cool to 0 - 6 °C. 
TABLE 2-40A (continued) 

RECOMMENDED SAMPLE CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING TIMES FOR ORGANI

 SW-846 Update V TWO - 66 

 

a The information presented in this table does not represent EPA requirements, but rather is intended solely as guidance. S

preservation techniques, and applicable holding times should be based on the stated project-specific DQOs.

1 The exact sample, extract, and standard storage temperature should be based on project-specific requirements and/or ma

recommendations for commercially available standards. Furthermore, alternative storage temperatures may be appropriate analyte stability in a given matrix, provided the stated DQOs for a project-specific application are still attainable. 

2 A longer holding time may be appropriate if it can be demonstrated that the reported analyte concentrations are not advers

preservation, storage, and analyses performed outside the recommended holding times. 

POLYCHLORINATED BIPHENYLS, POLYCHLORINATED DIBENZO-p-DIOXINS, AND POLYCHLORINATED DIBENZ

Sample Matrix Container Preservative1 Concentrated waste samples 

125-mL wide-mouth glass with PTFE-lined lid 

None 

Aqueous samples with no 

residual chlorine present 

4 x 1-L amber glass container with PTFElined lid, or other size, as appropriate, to allow use of entire sample for analysis. 

Cool to 0 - 6 °C. 

Aqueous samples WITH 

residual chlorine present 

4 x 1-L amber glass container with PTFElined lid, or other size, as appropriate, to allow use of entire sample for analysis. 

Add 3 mL 10% sodium thiosulfate solution per 

gallon (or 0.008%). Addition of sodium thiosulfate solution to sample container may be performed in the laboratory prior to field use. Cool to 0 - 6 °C 

Solid samples (e.g., soils, sediments, sludges, ash) 

250-mL wide-mouth glass container with PTFE-lined lid. 

Cool to 0 - 6 °C. 
SW-846 Update V TWO - 67 

 

TABLE 2-40B 

RECOMMENDED CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING TIMES FOR INORGA

OTHER ANALYTES IN AQUEOUS MATRICES 

(SEE CHAPTER THREE FOR MORE DETAILED GUIDANCE, INCLUDING REGARDING SOLID MATR

(Footnotes are located on the next page.) 

Name Container1 Preservation2 Inorganic Tests: Chloride P, G None required Cyanide, total and amenable to chlorination 

P, G Cool to 0 - 6 ̊C; if oxidizing agents present add 5 mL 0.1N NaAsO2

per L or 0.06 g of ascorbic acid per L; adjust pH>12 with 50% NaOH. See Method 9010 for other interferences. 

Hydrogen ion (pH) P, G None required Nitrate P, G Cool to 0 - 6 ̊C. Sulfate P, G Cool to 0 - 6 ̊C. Sulfide P, G Cool to 0 - 6 ̊C , add zinc acetate, NaOH to pH >9 Metals: Chromium VI P, G Cool to 0 - 6 ̊C. 

Mercury P, G HNO3 to pH<2 

Mercury (soil/sediment) P, G Cool to 0 - 6 ̊C. Mercury Species in soil/sediment P, G Cool to 0 - 6 ̊C. 

All Other Metals P, G HNO3 to pH<2 

Hexane Extractable Material (HEM; Oil and grease) 

G Cool to 0 - 6 ̊C,HCl or H2SO4 to pH<2 

Organic carbon, total (TOC) P, G Cool to 0 - 6 ̊C, store in dark; HCl or H2SO4 to pH<2 Radiological Tests: 
SW-846 Update V TWO - 68 

 

Name Container1 Preservation2 

Alpha, beta and radium P, G HNO3 to pH<2 

a The information presented in this table does not represent EPA requirements, but rather is intended solely as guid

containers, preservation techniques and applicable holding times should be based on the stated project-specific D

Three, Chapter Four, or the individual methods for more information. 

1 Polyethylene (P) or glass (G) 2 The exact sample, extract, and standard storage temperature should be based on project-specific requirements a

recommendations for commercially available standards. Furthermore, alternative storage temperatures may be ademonstrated analyte stability in a given matrix, provided the stated DQOs for a project-specific application are st

3 A longer holding time may be appropriate if it can be demonstrated that the reported analyte concentrations are no

by preservation, storage, and analyses performed outside the recommended holding times. 
SW-846 Update V TWO - 69 Revision 5 

 July 2014 

TABLE 2-41 

PREPARATION METHODS FOR ORGANIC ANALYTES 

(Note: Footnotes are located on the last page of the table.) 

 Matrix 

Analyte Type Aqueous1 Solids 

Sludges and 

Emulsions1,2

Organic 

Liquids, 

Tars, Oils 

Acid Extractable 35103520 

(pH ≤ 2) 

3540 

3541 

354213

3545 

3546 

3550 

3520 

(pH ≤ 2) 

3650 

35803

Acrolein12, Acrylonitrile12, and 

Acetonitrile 

5031 

503212

5031 

503212

5031 

503212

3585 

Acrylamide 80324 

Aniline and Selected 

Derivatives 

3510 

3520 

(pH >11) 

503111

3540 

3541 

3545 

3550 

3520 

(pH >11) 

35803

Aromatic Volatiles 5021 

5030 

5032 

5021 

5032 

5035 

5030 

5032 

3585 

Base/Neutral Extractable 3510 

3511 

3520 

(pH >11) 

3540 

3541 

354213

3545 

3546 

3550 

3520 

(pH >11) 

3650 

35803

Carbamates 83185

8321 

83185

8321 

83185 83185

 

Chlorinated Herbicides 3535 

(pH < 1) 

81516

(pH ≤ 2) 

8321 

3545 

3546 

81516

8321 

81516

(pH ≤ 2) 

35803

Chlorinated Hydrocarbons 3510 

3520 

(pH as 

received) 

3540 

3541 

3550 

3520 

(pH as 

received) 

35803

Dyes 3510 

3520 

3540 

3541 

3545 

3550 

 
SW-846 Update V TWO - 70 Revision 5 

 July 2014 

TABLE 2-41 (continued) 

PREPARATION METHODS FOR ORGANIC ANALYTES 

Matrix 

Analyte Type Aqueous1 Solids 

Sludges and 

Emulsions1,2

Organic 

Liquids, 

Tars, Oils 

Explosives 3535 

83307

83318

83307

83318

 

Formaldehyde 83159 83159 

Haloethers 3510 

3520 

3540 

3541 

3545 

3550 

Halogenated Volatiles 5021 

5030 

5032 

5021 

5032 

5035 

5030 5021 

(methanol extr) 

5035 / 5030 

(methanol extr) 

5032 

3585 

Nitroaromatics 

and Cyclic Ketones 

3510 

3520 

(pH 5-9) 

3535 

3540 

3541 

3545 

3550 

3520 

(pH 5-9) 

35803

Nitrosamines 3510 

3520 

3540 

3541 

3545 

3550 

 

Non-halogenated Volatiles 5021 

5030 

5031 

5032 

5021 

5031 

5032 

5035 

5021 

5031 

5032 

5021 

(methanol extr) 

5035 / 5030 

(methanol extr) 

5032 

3585 

Organochlorine Pesticides 3510 

3520 

3535 

(pH 5-9) 

3540 

3541 

3545 

3546 

3550 

3562 

3520 

(pH 5-9) 

35803

Organophosphorus 

Pesticides 

3510 

3520 

(pH 5-8) 

3535 

3540 

3541 

3545 

3546 

3520 

(pH 5-8) 

35803
SW-846 Update V TWO - 71 Revision 5 

 July 2014 

1

 The pH at which extraction should be performed is shown in parentheses. 

2

 If attempts to break an emulsion are unsuccessful, these methods may be used. 

3

 Method 3580 is only appropriate if the sample is soluble in the specified solvent. 

4

 Method 8032 contains the extraction, cleanup, and determinative procedures for this analyte. 

TABLE 2-41 (continued) 

PREPARATION METHODS FOR ORGANIC ANALYTES 

Matrix 

 Aqueous1 Solids 

Sludges and 

Emulsions1,2

Organic 

Liquids, 

Tars, Oils 3650 

35803

Phenols 3510 

3520 

(pH ≤ 2) 

3535 

3540 

3541 

3545 

3546 

3550 

3562 

3520 

(pH ≤ 2) 

3650 

35803

Phthalate Esters 3510 

3520 

3535 

(pH 5-7) 

3540 

3541 

3545 

3546 

3550 

3520 

(pH 5- 7) 

35803

Polychlorinated Biphenyls 3510 

3520 

3535 

(pH 5-9) 

3540 

3541 

3545 

3546 

3562 

3520 

(pH 5-9) 

35803

PCDDs and PCDFs 828010

829010

3545 

3546 

828010

829010

828010

829010

828010

829010

Polynuclear Aromatic 

Hydrocarbons 

3510 

3511 

3520 

(pH as 

received) 

3540 

3541 

3545 

3546 

3550 

3561 

3520 

(pH as 

received) 

35803

Volatile Organics 5021 

5030 

5031 

5032 

5021 

5031 

5032 

5035 

5021 

5030 

5031 

5032 

5021 

(methanol extr) 

5035 / 5030 

(methanol extr) 

5032 

3585 

Wipes (Chemical Agents 

only) 

 3572 
SW-846 Update V TWO - 72 Revision 5 

 July 2014 

5

 Method 8318 contains the extraction, cleanup, and determinative procedures for these analytes. 

6

 Method 8151 contains the extraction, cleanup, and determinative procedures for these analytes. 

7

 Method 8330 contains the extraction, cleanup, and determinative procedures for these analytes. 

8

 Method 8331 is for Tetrazene only, and contains the extraction, cleanup, and determinative 

procedures for this analyte. 

9

 Method 8315 contains the extraction, cleanup, and determinative procedures for this analyte. 

10 Methods 8280 and 8290 contain the extraction, cleanup, and determinative procedures for these 

analytes. 

11 Method 5031 may be used when only aniline is to be determined. 

12 Method 5032 may be used for acrolein and acrylonitrile. 

13 Method 3542 is used for extraction of semivolatiles from stack samples collected using Method 

0010. 
SW-846 Update V TWO - 73 Revision 5 

 July 2014 

 TABLE 2-42 

 CLEANUP METHODS FOR ORGANIC ANALYTE EXTRACTS 

Analyte Type Method 

Acid Extractable 3650, 3640 

Base/Neutral Extractable 3650, 3640 

Carbamates 83181

Chlorinated Herbicides 81512

Chlorinated Hydrocarbons 3620, 3640 

Haloethers 3620, 3640 

Nitroaromatics & Cyclic Ketones 3620, 3640 

Nitrosamines 3610, 3620, 3640 

Organochlorine Pesticides 3620, 3630, 3640 

3660 

Organophosphorus Pesticides 3620 

Phenols 3630, 3640, 3650 

80413

Phthalate Esters 3610, 3611, 3620 

3640 

Polychlorinated Biphenyls 3620, 3630, 3640 

3660, 3665 

Polychlorinated Dibenzo-p-Dioxins and Polychlorinated Dibenzofurans 82804

82904

Polynuclear Aromatic Hydrocarbons 3610, 3611 

3630, 3640, 

3650 

1

 Method 8318 contains the extraction, cleanup, and determinative procedures for these analytes. 

2

 Method 8151 contains the extraction, cleanup, and determinative procedures for these analytes. 

3

 Method 8041 includes a derivatization technique followed by GC/ECD analysis, if interferences are encountered using GC/FID. 

4

 Methods 8280 and 8290 contain the extraction, cleanup, and determinative procedures for these analytes. 
SW-846 Update V TWO - 74 Revision 5 

 July 2014 

TABLE 2-43 

 DETERMINATIVE METHODS ORGANIC ANALYTES 

Analyte Type 

GC/MS 

Method 

Specific GC 

Method6

HPLC 

Method 

Acid Extractable 8270 84106 

Acrolein, Acrylonitrile, Acetonitrile 8260, 8261 8015, 8031, 

80331

 83152, 8316 

Acrylamide 8260 8032 8316 

Aniline and Selected Derivatives 8270 8131 

Aromatic Volatiles 8260, 8261 8021 

Base/Neutral Extractable 8270 84106

 83254

Carbamates 8318, 8321 

Chlorinated Herbicides 82703 8151 8321 

Chlorinated Hydrocarbons 8270 8121 

Diesel Range Organics (DRO) 8015, 84407

 

Dyes 8321 

Explosives 8095 8330, 8331, 8332 

Formaldehyde 8315 

Gasoline Range Organics (GRO) 8015 

Haloethers 8270 8111, 8430 

Halogenated Volatiles 8260, 8261 8011, 8021 

Nitroaromatics and Cyclic Ketones 8270 8091 83305

Nitrosoamines 8270 8070 

Non-halogenated Volatiles 8260 8015 8315 

Organochlorine Pesticides 82703, 8276 8081, 80856 

Organophosphorus Pesticides 82703 8141, 80856 8321 

Phenols 8270 8041, 84106 

Phthalate Esters 8270 8061, 84106 

Polychlorinated Biphenyls 82703 8082 

PCDDs and PCDFs 8280, 8290 

Polynuclear Aromatic Hydrocarbons 8270 8100, 84106

 8310 

Volatile Organics 8260, 8261 8011, 8015, 

8021, 8031, 

8032, 8033 

8315, 8316 

1

 Of these analytes, Method 8033 is for acetonitrile only. 

2

 Of these analytes, Method 8315 is for acrolein only. 

3

 This method is an alternative confirmation method, not the method of choice. 

4

 Benzidines and related compounds. 

5

 Nitroaromatics (see "Explosives"). 

6

 Includes GC/ES methods, e.g., Methods 8085 and 8410. 

7

 FT-IR determinative method only. Does not use GC.
SW-846 Update V TWO - 75 Revision 5 

 July 2014 

TABLE 2-44 

 PREPARATION METHODS FOR INORGANIC ANALYSES 1

Matrix Method 

Surface water 3005, 3010, 3015, 3020 

Groundwater 3005, 3010, 3015, 3020 

Extracts 3010, 3015, 3020 

Aqueous samples containing suspended solids 3010, 3015, 3020 

Oils 3031, 3040, 3051, 30522

Oil sludges 3031, 30522

Tars 3031, 30522

Waxes 3031, 3040, 30522

Paints 3031, 30522

Paint sludges 3031, 30522

Petroleum products 3031, 3040, 30522

Sediments 3050, 3051, 30522, 30603, 32004

Sludges 3050, 3051, 30522

, 30603

Soil samples 3050, 3051, 30522, 30603, 32004

Ashes 30522

Biological tissues 30522

1

It is the responsibility of the analyst to refer to each analytical method to determine applicability 

of the chosen method to a specific waste type and target analyte. 

2For total decomposition analysis ONLY. 

3For the analysis of samples for hexavalent chromium ONLY. 

4For the analysis of samples for mercury or mercury species ONLY.
SW-846 Update V TWO - 76 

TABLE 2-45 

USE OF LEACHING, EXTRACTION AND DIGESTION METHODS 

FOR INORGANIC ANALYSIS (In order of increasing strength) 

Method Method Name Reagents & Conditions 

1310 Extraction Procedure (EP) Toxicity Test 

Method and Structural Integrity Test 

Dilute acetic acid Simulate leac

from codisposmunicipal wa

1311 Toxicity Characteristic Leaching Procedure Extraction Fluid # 1 -- Dilute glacial acetic 

acid and NaOH, pH 4.93 ± 0.05 Extraction Fluid # 2 -- Dilute glacial acetic acid, pH 2.88 ± 0.05 

Simulate leacfrom codisposmunicipal wa

1312 Synthetic Precipitation Leaching Procedure Dilute H2SO4 and HNO3 (synthetic acid rain) Simulate acid 

1313 Liquid-Solid Partitioning as a Function of 

Extract pH Batch Extraction Procedure 

Dilute HNO3, KOH Industrial was

combustion restabilized mamaterials, and 

1316 Liquid-Solid Partitioning as a Function of 

Liquid-to-Solid Ratio in Solid Materials Using a Parallel Batch Procedure 

None Industrial was

combustion restabilized mamaterials, and 

1320 Multiple Extraction Procedure Dilute H2SO4 and HNO3 (synthetic acid rain) Simulate long

a waste 

3005 Acid Digestion of Waters for Total 

Recoverable or Dissolved Metals Analysis by FLAA or ICP Spectroscopy 

HNO3, heat Surface wate

3010 Acid Digestion of Aqueous Samples and 

Extracts for Total Metals for Analysis by FLAA or ICP Spectroscopy 

HNO3, HCl, heat Aqueous sam

3015 Microwave Assisted Acid Digestion of 

Aqueous Samples and Extracts 

HNO3 or alternatively HNO3 and HCl, 

(pressure, heat) 

Aqueous sam
SW-846 Update V TWO - 77 

TABLE 2-45 (continued) 

USE OF LEACHING, EXTRACTION AND DIGESTION METHODS 

FOR INORGANIC ANALYSIS (In order of increasing strength) 

Method Method Name Reagents & Conditions 

3020 Acid Digestion of Aqueous Samples and 

Extracts for Total Metals for Analysis by GFAA Spectroscopy 

HNO3, heat Aqueous sam

GFAA work o

3031 Acid Digestion of Oils for Metals Analysis by 

Atomic Absorption or ICP Spectrometry 

Potassium permanganate, H2SO4, HNO3, 

HCl, heat 

Oils, oily sludpaint sludge, petroleum pro

3040 Dissolution Procedure for Oils, Greases, or 

Waxes 

Solvent (e.g., xylene, kerosene, or MIBK) Dissolution of 

and waxes 

3050 Acid Digestion of Sediments, Sludges, and 

Soils 

HNO3 and H2O2, heat 

(for GFAA or ICPMS) HNO3, H2O2, and HCl, heat (for ICP-AES or FLAA) 

Sediments, s

3051 A Microwave Assisted Acid Digestion of 

Sediments Sludges, Soils, and Oils 

HNO3, or alternatively HNO3 and HCl, 

microwave assisted (pressure, heat) 

Sludges, sed

3052 Microwave Assisted Acid Digestion of 

Siliceous and Organically Based Matrices 

HNO3, HF, HCl (optional) H2O2 (optional), 

heat, pressure 

Siliceous, orgmatrices for t

3060A Alkaline Digestion for Hexavalent Chromium Na2CO3/NaOH, heat Soils, sludges

industrial washexavalent ch

1 As described in the respective background documents developed in support of the rulemakings, which added required us

the Toxicity Characteristic regulation (Method 1311 replaced Method 1310 for Toxicity Characteristic determinations on M

11862). 
SW-846 Update V TWO - 78 Revision 5 

 July 2014 

TABLE 2-46 

SCREENING METHODS FOR ORGANIC ANALYTES 

 Matrix 

Analyte Type Aqueous Solids 

Sludges and 

Emulsions 

Organic 

Liquids, 

Tars, Oils 

Chlordane 4041 

2,4-Dichlorophenoxyacetic 

acid 

4015 4015 

Hexahydro-1,3,5-trinitro1,3,5-triazine (RDX)  4051 

8510 

 

Octahydro-1,3,5,7-tetranitro1,3,5,7-tetrazocine (HMX)  8510 

Pentachlorophenol 4010 4010 

8540 

4010 

Petroleum Hydrocarbons 4030 

Poly-Chlorinated Biphenyls 

(PCBs) 

4425 

(coplanar) 

4020 

4425 

(coplanar) 

 4020 

(non-aqueous) 

Polychlorinated 

Dibenzodioxins 

4425 4425 

Polychlorinated 

Dibenzofurans 

4425 4425 

Polynuclear Aromatic 

Hydrocarbons (PAHs) 

4425 4035 

4425 

 

Toxaphene 4040 

Triazine Pesticides 4670 

(quantitative) 

 

1,1,1,-Trichloro-2,2-

bis(chlorophenyl)ethane 

(DDT) and breakdown 

products 

 4042 

Trinitrotoluene (TNT) 4050 

8515 

 
SW-846 Update V TWO - 79 Revision 5 

Sample

Is sample

 to be analyzed for

extractables or

volatiles?

Physical

characteristic of

sample.

Sample Prep:

5030, 5031, 5032,

8011

Sample Prep:

3585

Analysis

Procedure?

Volatile

Aqueous Liquid

Sample Prep:

5021, 2032, 5035

Solid or Sludge

Organic Liquid or Oil

GC/MS Anaylsis

Procedure:8260, 8261

GC/MS

GC Analysis Procedures :EDB and DBCP: 8011Nonhalogenated Volatile Compounds: 8015Halogenated Volatile Compounds: 8021Acrylonitrile: 8031Acrylamide: 8032Acetonitrile: 8033

HPLC Analysis Procedures:Acrolein, Acrylonitrile, Acrylanide: 8316Carbaryl Compounds: 8315

GC

HPLC

Dioxin?

Physical

characteristic of

sample.

Extraction

Procedure:

3510, 3520, 3535

Extraction

Procedure:

3540, 3541, 3545,3546, 3550, 3560,

3561, 3562, 3580

Is cleanup

needed?

Extractable

Aqueous Sample

Organic Liquid

Oil

Solid

Cleanup Procedures:Alumina Column: 3610

Alumina Column for Petroleum Wastes: 3611

Florisil Column: 3620Silicia Gel Column: 3630Gel Permeation: 3640

Acid Base Partitioning: 3650

Sulfure: 3660

Sulfuric Acid Cleanup: 3665

H PLC Analysis Procedures :

8310, 8318, 8321, 8325,

8330, 8331, 8332

Yes

No

Yes 

No

Analysis

Procedure?

GC/MS

Procedure:

8270, 8275

GC/MS

HPLC

GC

FIGURE 2-1 

ORGANIC ANALYSIS OPTIONS FOR SOLID AND LIQUID MATRICES 

For illustrative purposes only. 

See the disclaimer and Sec. 2.1 for information on the flexibility inherent in SW-846 methods. NOTE: Not all clean-up methods are applicable to all listed methods. Consult the individual methods for furthe

clean-up methods are applicable and appropriate. 
SW-846 Update V TWO - 80 Revision 5 

 July 2014 

FIGURE 2-2 

SCHEMATIC OF SEQUENCE TO DETERMINE 

IF A WASTE IS HAZARDOUS BY CHARACTERISTIC 
SW-846 Update V TWO - 81 Revision 5 

 July 2014 

FIGURE 2-2 (continued) 

1. Users can find information regarding the corrosivity characteristic for samples in a gel matrix 

at:http://yosemite.epa.gov/osw/rcra.nsf/0/7D573EA3E0F1576D8525670F006BEA5F/$file/11719.pdf. 

2. Biphasic or multiphasic waste can present a unique challenge. More information can be found on this topic in the 

Federal Register (Dec 21, 1995 FR (page 66389). This can be found online at: 

http://nepis.epa.gov/Exe/ZyNET.exe/10001E3Y.txt?ZyActionD=ZyDocument&Client=EPA&Index=1995%20Thru%2019

99&Docs=&Query=&Time=&EndTime=&SearchMethod=1&TocRestrict=n&Toc=&TocEntry=&QField=&QFieldYear=&Q

FieldMonth=&QFieldDay=&UseQField=&IntQFieldOp=0&ExtQFieldOp=0&XmlQuery=&File=D%3A\ZYFILES\INDEX%2

0DATA\95THRU99\TXT\00000000\10001E3Y.txt&User=ANONYMOUS&Password=anonymous&SortMethod=h|-

&MaximumDocuments=1&FuzzyDegree=0&ImageQuality=r75g8/r75g8/x150y150g16/i425&Display=p|f&DefSeekPage

=x&SearchBack=ZyActionL&Back=ZyActionS&BackDesc=Results%20page&MaximumPages=1&ZyEntry=48

 
SW-846 Update V TWO - 82 Revision 5 

 July 2014 

FIGURE 2-3A 

 RECOMMENDED SW-846 METHODS FOR ANALYSIS OF EP LEACHATES 
SW-846 Update V TWO - 83 Revision 5 

 July 2014 

FIGURE 2-3B 

RECOMMENDED SW-846 METHODS FOR ANALYSIS OF TCLP LEACHATES 
SW-846 Update V TWO - 84 Revision 5 

 July 2014 

FIGURE 2-4A 

 GROUNDWATER ANALYSIS - ORGANIC ANALYTES 

For illustrative purposes only. 

See the disclaimer and Sec. 2.1 for information on the flexibility inherent in SW-846 methods. 
SW-846 Update V TWO - 85 Revision 5 

 July 2014 

FIGURE 2-4B 

 GROUNDWATER ANALYSIS - INDICATOR ANALYTES 

For illustrative purposes only. See the disclaimer and Sec. 2.1 regarding the flexibility inherent in SW-846 methods. 
SW-846 Update V TWO - 86 Revision 5 

 July 2014 

FIGURE 2-4C 

 GROUNDWATER ANALYSIS - INORGANIC ANALYTES 

For illustrative purposes only. See the disclaimer and Sec. 2.1 regarding the flexibility inherent in SW-846 methods. 
SW-846 Update V TWO - 87 Revision 5 

 July 2014 

Appendix A: Summary of Updates/Changes in Chapter 2

1. Improved overall method formatting for consistency with new SW-846 methods style 

guidance. The entire document was reformatted in Microsoft Word.docx format from the 

original .WPD and .PDF files. 

2. The revision number was changed to five and the published date to July 2014. 

3. A Table of Contents was compiled and added to make finding information easier. 

4. Minor editorial and grammatical changes (e.g., removing extra spaces between words, 

adding commas, etc.) were made throughout Sections 1.0 to 2.7. The disclaimer 

statement in Section 1.0 was numbered to keep the format consistent, as it started at 

Section 2.0 originally. 

5. Graphics in the Figures Section were modified from Corel Drawing Objects V.10 to .jpg 

graphical images where needed to remove artifacts from the conversion process. The 

text titles of each figure was centered and formatted. 

6. This appendix was added to document non-significant changes made during the editorial 

process. 

7. Bis(2-chloroisopropyl) ether was corrected to Bis(2-chloro-1-methylethyl) ether in Tables 

2-1, 2-4, 2-15, 2-22, and 2-34. 

8. Revised Table 2-40A to reflect current sample preservation guidance for styrene and 

vinyl chloride in aqueous samples (i.e., deletion of previously recommended practice of 

collecting a second set of samples without acid preservatives and analyze immediately, 

if styrene and vinyl chloride are analytes of interest). 

9. Revised Table 2-41. 

10. Revised Table 2-45 to include Methods 1313 and 1316. 

11. Added Table 2-46. 

12. Added Figure(s) for new leaching procedure(s). 

13. Revised Table 2-40B to include Mercury Speciation hold times in addition to totals. 

14. All other tables were updated with the target compound list in the current published 

methods.