DRAFT—NOT FOR FURTHER DISTRIBUTION

Dow AgroSciences

Product Use Guide

for EnlistTM Corn 
DRAFT—NOT FOR FURTHER DISTRIBUTION

Stewardship Overview

Dow AgroSciences is committed to promoting the responsible use and stewardship of its products

throughout the product life cycle. Consistent with its ongoing stewardship programs and practices, 

Dow AgroSciences has implemented comprehensive stewardship measures for EnlistTM corn and Enlist 

DuoTM herbicide.

This Product Use Guide (PUG) details requirements and recommendations for the planting of Enlist corn

and the proper use of Enlist Duo herbicide featuring Colex-D

TM Technology. This PUG is not a pesticide 

product label. It is intended to provide additional information and to highlight approved uses from specific 

product labels. Read and follow all precautions and directions on the product labels and any 

supplemental labeling for Enlist Duo herbicide featuring Colex-D Technology, Dow AgroSciences 

Authorized Herbicide Product(s), as well as any other pesticide products. As a grower planting 

Enlist corn, you must be both familiar with and follow the Technology Use Agreement (Agreement) and 

this associated PUG.

Technology Use Agreement

NOTE: YOU MUST HAVE A VALID, EXECUTED TECHNOLOGY USE AGREEMENT ON FILE WITH 

DOW AGROSCIENCES TO LEGALLY OBTAIN, PLANT AND GROW CORN THAT CONTAINS DOW 

AGROSCIENCES’ ENLIST TRAIT.

Failure to comply with the terms of the Agreement or this PUG can result in your losing the privilege to 

grow seed containing the Enlist technology. You must communicate all applicable terms, conditions and 

restrictions on your EnlistTM corn to all persons and entities possessing or taking an interest in your Enlist 

corn crop and/or the grain therefrom. You may complete the Agreement online at:

www.traitstewardship.com, or obtain a copy by calling 877-4-TRAITS (877-487-2487) or by contacting 

your Seed Provider.

By signing the Agreement, you receive a limited, non-transferable, revocable, non-exclusive license by 

Dow AgroSciences under the Licensed Rights to purchase Seed from Seed Seller and to plant Purchased 

Seed to produce a single commercial crop in the United States. In addition, when you purchase Seed 

and plant Purchased Seed containing Enlist Technology, you shall receive a limited license to apply Dow 

AgroSciences Authorized Herbicide Products in Enlist crops grown from such Purchased Seed. 

You will also receive the most current PUG and other periodic updates relating to Enlist corn.

By purchasing and using Dow AgroSciences technologies and traits under the Agreement, you reaffirm 

your commitment to the Agreement you signed, and to follow applicable PUGs and herbicide product 

labels. The seed you purchase is for your use and cannot be given, sold or otherwise transferred to 

others.

Always consult your trait provider’s technical guides before planting. ALWAYS READ AND 

FOLLOW PESTICIDE LABEL DIRECTIONS. Please direct questions about this PUG or corn that 

contains Dow AgroSciences’ Corn technologies and traits to your seed provider or to Dow 

AgroSciences at 877-4-TRAITS (877-487-2487).

Compliance Monitoring

Dow AgroSciences will monitor compliance with the Agreement and PUG through surveys and on-farm 

assessments. Upon request by Dow AgroSciences, you must provide information regarding the location

of fields planted with Enlist corn and the herbicides applied to these fields. Failure to follow these 

stewardship requirements will result in action by Dow AgroSciences which may include additional 

education and training, monitoring, and/or loss of access to the technology.
DRAFT—NOT FOR FURTHER DISTRIBUTION

EnlistTM Corn 

The Enlist trait confers tolerance to 2,4-D and quizalofop, and will be stacked with the glyphosate 

tolerance trait in Enlist corn hybrids. This offers growers the benefits of tolerance to in-crop applications of 

Enlist Duo and other Dow AgroSciences’ Authorized Herbicide Products to reduce weed competition 

while using herbicides with multiple modes of action as part of its management practices.

In addition to herbicide tolerance, some Enlist hybrids will contain Bt traits that confer insect protection. If 

you purchase hybrids that contain Bt traits, you must also follow applicable Insect Resistance

Management requirements. Consult the appropriate PUG for refuge requirements.

Volunteer Control

Enlist corn is tolerant to 2,4-D, glyphosate and quizalofop herbicides. It is recommended that a “-dim” 

herbicide, such as Select®(clethodim) or Poast Plus®(sethoxydim), be used to control volunteer Enlist 

corn in soybeans.

Coexistence

Corn is a naturally cross-pollinated crop, and a small amount of corn pollen movement to nearby fields is 

not uncommon. You can take steps to reduce the occurrence and extent of undesired pollen movement. 

These steps include: maintaining a non-corn buffer between cornfields containing biotechnology traits and 

conventional cornfields; not growing corn with biotech traits upwind (based on the prevailing wind 

directions) of other corn fields; and discussing your cropping plans with your neighbors in advance.

Crop and Grain Marketing Stewardship

Dow AgroSciences is a member of Excellence Through Stewardship®(ETS). Dow AgroSciences’ 

products are commercialized in accordance with ETS product launch stewardship guidance, and Dow 

AgroSciences’ Product Launch Stewardship Policy. 

Direct grain produced from these crops to appropriate markets as necessary. Any crop or material 

produced from these products can only be exported to, or used in, processed in or sold in countries 

where all necessary regulatory approvals have been granted. It is a violation of national and international 

law to move material containing biotechnology traits across boundaries into nations where import is not 

permitted. Talk to your grain handler or product purchaser to confirm their buying position for this product.

For further information about your crop marketing options, contact Dow AgroSciences at 877-4-TRAITS 

(877-487-2487). Information regarding the regulatory and market status of agricultural biotechnology 

products can be found at: www.biotradestatus.com.

Authorized Herbicides with EnlistTM Corn

Enlist corn contains the patented gene that provides tolerance to 2,4-D and quizalofop herbicides. The 

Enlist trait is also stacked with the glyphosate trait in Enlist corn hybrids.

The only 2,4-D containing herbicides that may be used are DAS Authorized Herbicide Products. 

“DAS Authorized Herbicide Product(s)” means agricultural products that contain either phenoxy 

carboxylic acid or AOPP herbicides or both that are expressly labeled for use with EnlistTM crops.

Examples of DAS Authorized Herbicide Products include:

 Enlist Duo (pending regulatory approval); use of other 2,4-D containing herbicides on Enlist corn is 

prohibited

 Assure®II herbicide (pending regulatory approval)

 Additional products will be listed, pending approvals
DRAFT—NOT FOR FURTHER DISTRIBUTION

Enlist DuoTM Herbicide with Colex-DTM Technology 

Crop Enlist corn

Active Ingredients 2,4-D Choline and Glyphosate DMA

Modes of Action Group 4 and Group 9

Formulation Soluble Liquid

Signal Word Warning

Use Rate In-Season Applications within the anticipated range of use rates: 2.5 - 4.75 pt/A

Surfactants/Oils Not Recommended

Application Timing Post-emergence to weeds

Droplet Size Coarse or Very Coarse spray 

Spray Volume 10-15 gpa

 *Read the Product Label for complete details

Weed Control with Enlist Duo Herbicide 

The lower use rates given on the Enlist Duo label will be satisfactory for young, succulent growth of 

sensitive weed species. For less sensitive species and under conditions where control is more difficult, 

the higher use rates will be needed. Apply Enlist DuoTM when weeds are young and actively growing, per 

the label directions. 

The product label for Enlist Duo contains the directions and recommendations for use over Enlist crops 

including application equipment requirements, product use directions, restrictions and precautions, weed 

management information, and other product information.

The Program Approach

A program approach, including Enlist Duo herbicide, aids in the management of herbicide resistance, 

reduces weed competition during critical crop growth stages and improves the overall consistency of 

weed control. It eliminates competition from a broad spectrum of early season grass and broadleaf 

weeds. The mode of action classification system of the Weed Science Society of America (WSSA) lists 

2,4-D as a Group 4 growth regulator herbicide (synthetic auxin) and glyphosate as a Group 9 herbicide 

(inhibitor of ESPP synthase). 

The recommended weed control program for EnlistTM corn is a PRE application herbicide product 

containing at least two non-Group 4/Group 9 modes of action, followed by a POST application of Enlist 

Duo herbicide. If a second POST application of Enlist Duo is required, it must occur at least 12 days after 

the first application, per the product label.
DRAFT—NOT FOR FURTHER DISTRIBUTION

Application

Read and follow product label, as well as follow state and local requirements related to application of 

pesticides. Apply Enlist DuoTM herbicide only with properly calibrated ground application equipment using 

appropriate carriers.

Boom Height

To minimize spray drift potential, use the minimum nozzle height recommended by the nozzle 

manufacturer based on configuration of the spray boom and spray angle of the nozzle tip. 

Spray Volume

Use a spray volume of 10-15 gallons or more per acre for ground equipment and apply with calibrated 

ground equipment. Do not apply less than 10 gallons total spray volume per acre. Where applicable, 

state regulations specifying minimum spray volumes must be observed. 

In general, increase spray volume as crop canopy, height and weed density increase to obtain adequate 

spray coverage.

Nozzle Selection

Proper spray nozzle selection plays a critical part in minimizing the potential for physical drift. Use low drift 

nozzles, according to the American Society of Agricultural and Biological Engineers (ASABE) S-572 

standard, that produce a coarse to very coarse spray and are designed for herbicide application. Ultra 

coarse droplet sizes may result in decreased weed control and increased crop injury.

Nozzle selection is a process that maximizes product performance by managing the interaction between 

application volume (GPA), nozzle flow rate (GPM), nozzle type, operating pressure, travel speed (MPH), 

nozzle spacing (W) and droplet size category. The following are examples that produce a coarse to very 

coarse spray with the appropriate settings. 

Manufacturer Model Psi Speed-mph

(20” spacing)

Speed-mph

(30” spacing)

Hypro ULD 120-04 15 - 70 6 - 10 4 - 7

ULD 120-05 30 - 90 10 - 15 7 - 10

ULD 120-06 40 - 100 12 - 20 8 – 13.5

Hypro GA 110-035 30 - 80 6 - 10 4 - 7

GA 110-04 30 - 80 8 - 12 5.5 - 8

GA 110-05 30 - 80 10 - 15 7 - 10

TeeJet AIXR 110-04 50 - 90 8 - 15 5.5 - 10

AIXR 110-05 50 - 90 10 - 15 7 - 10

AIXR 110-06 50 - 90 12 - 20 8 - 13.5

TeeJet AI 110-04 50 - 100 8 - 15 5.5 - 10

AI 110-05 50 - 100 10 - 15 7 - 10

AI 110-06 50 - 100 12 - 20 8 - 13.5

®TeeJet Technologies is a subsidiary of Spraying Systems Company.

Spray Drift Management 

Wind 

Drift potential is lowest at wind speeds less than 10 mph. Target applications at wind speeds greater than 

3 mph but less than 10 mph. Do not apply at wind speeds greater than 15 mph.

The product should not be applied at wind speeds less than 3 mph where temperature inversion or stable 

atmospheric conditions could exist. 

Local terrain can influence wind patterns. The applicator should be familiar with local wind patterns and 

how they affect drift.
DRAFT—NOT FOR FURTHER DISTRIBUTION

Temperature and Humidity

When making applications in low relative humidity, set up equipment to produce larger droplets to 

compensate for evaporation. Droplet evaporation is most severe when conditions are both hot and dry.

Susceptible Plants 

Do not apply under circumstances where spray drift may occur to food, forage, or other plantings that 

might be damaged or crops thereof rendered unfit for sale, use or consumption. Avoid contact of 

herbicide with foliage, green stems, exposed non-woody roots of crops, desirable plants and trees 

because severe injury or destruction may result. Small amounts of spray drift that may not be visible may 

injure susceptible broadleaf plants. Before making an application, please refer to your state’s sensitive 

crop registry (if available) to identify any commercial specialty or certified organic crops that may be 

located nearby. Commercially grown tomatoes and other fruiting vegetables (EPA crop group 8), 

cucurbits (EPA crop group 9), and grapes are particularly sensitive to drift from this product. Do not apply 

when wind direction favors off-target movement onto these crops.

Setbacks

Setbacks for Enlist DuoTM herbicide are directional, meaning they would only apply downwind of the spray 

application.

Setback Distances Upwind of Sensitive Areas*: [Pending EPA approval of the product label]

Setback Distance*: 

Allow setbacks (buffer zones) upwind of sensitive area (e.g., residential areas, bodies of water, known 

habitat for threatened or endangered species, and sensitive non-target crops other than those listed 

above) according to the following:

Wind Speed

(mph)

Spray Boom <24 Inches

Above Canopy

(ft)

Spray Boom >24 Inches

Above Canopy

(ft)

<5 15 30

5 – 10 40 80

10 – 15 80 150

*If a coarse or very coarse droplet classification cannot be maintained, an upwind setback of 250 feet 

from sensitive areas must be observed. 

Mixing Instructions

This product mixes readily with water. Mix spray solutions of this product as follows:

1. Fill the mixing or spray tank with the required amount of clean water. If addition of ammonium 

sulfate is desired to enhance performance of the product, see the ammonium sulfate section 

of the herbicide product label.

2. Add the specified amount of this product near the end of the filling process and mix well. 

During mixing and application, foaming of the spray solution may occur. To prevent or 

minimize foaming, use a commercial defoamer or avoid the use of mechanical agitators, 

and/or terminate by-pass and return lines at the bottom of the tank.

Note: Use approved anti-back siphoning devices where required by state or local regulations to 

avoid siphoning back into the carrier source.

Adjuvants (except Ammonium Sulfate) 

Enlist Duo herbicide contains low drift properties. The use of adjuvants and drift control additives with 

Enlist Duo herbicide with Colex-D Technology can have a negative impact on stability and application 

performance. The addition of some adjuvants may also result in increased crop injury, decreased weed 

control, and/or increased potential for spray drift. The compatible adjuvants for use with Enlist Duo are 
DRAFT—NOT FOR FURTHER DISTRIBUTION

listed below. If an adjuvant is desired for use with Enlist Duo, it must be selected from this list of 

products. Dow AgroSciences is released of all performance liability if a non-compatible adjuvant is used.

 List of Adjuvants will be inserted into final Product Use Guide

Tank Mixing with Other Products

Some herbicides, fungicides, micronutrients and insecticide products may require drift management and 

application equipment set-ups that differ from Enlist DuoTM herbicide. Additionally, the formulation 

components of some products may contain inert ingredients that negatively affect the low-drift properties 

offered with Enlist Duo with Colex-D Technology. The approved list of tank mix partners is below. Tank 

mix to the most restrictive label. If the most restrictive label reduces the agronomic benefit of an 

approved tank mix partner to an unacceptable level (i.e. a fungicide being applied in a coarse droplet), 

these products should not be tank-mixed with Enlist Duo herbicide.

 List of Approved Tank Mix Partners will be inserted into final Product Use Guide

Restrictions

Refer to the product label for specific planting restrictions, weed height and use information for annual 

and perennial weeds. During the growing season following application, do not replant fields with crops 

other than those labeled for use with 2,4-D and glyphosate.

Recordkeeping

As part of good farm management practices, you are encouraged to keep detailed spray records, 

including:

• Field location and number of acres sprayed

• Crop sprayed and stage of growth

• Date of application, start time, and finish time 

• Herbicide sprayed and application rate

• Nozzles used and operating pressure

• Travel speed and application rate (GPA)

• Air temperature and relative humidity

• Wind speed and direction

• Sprayer and boom cleanout

Sprayer and Equipment Cleanout

To avoid injury to desirable plants, properly clean equipment used to apply this product before 

reuse or using the equipment to apply other chemicals.

If the crop following the application of Enlist Duo is an application to glyphosate-tolerant corn: rinse the 

spray equipment with clean water to at least 10 percent of the total tank volume and spray the solution 

out of the spray tank through the boom.

If the application immediately following Enlist Duo is to any other crop, use the triple-rinse sprayer 

cleanout procedure for Enlist DuoTM herbicide below:
DRAFT—NOT FOR FURTHER DISTRIBUTION

 Completely drain the spray system, including lines and spray boom, for at least five minutes. 

 Fill the container with clean water to at least 10 percent of the total tank volume and circulate the 

solution through the entire system so that all internal surfaces are contacted for at least 15 

minutes to complete the first rinse of the application equipment. Spray the solution out of the 

spray tank through the boom. 

 Completely drain the spray system, including lines and spray boom if possible, for at least five 

minutes; remove and clean filters and strainers.

 Fill the container with clean water to at least 10 percent of the total tank volume. During the 

second rinse, tank cleaning agents may be added at the manufacturer’s recommended rates. 

Circulate the solution through the entire system so that all internal surfaces are contacted for at 

least 15 to 20 minutes. Let the solution stand for several hours, preferably overnight. Spray the 

solution out of the spray tank through the boom.

 Completely drain the spray system, including lines, spray boom and dead ends if possible, for at 

least five minutes. Follow manufacturer directions for addressing dead ends on spray booms.

 Fill the container with clean water to at least 10 percent of the total tank volume and circulate the 

solution through the entire system so that all internal surfaces are contacted for at least 15 

minutes to complete the third rinse of the application equipment. Spray the solution out of the 

spray tank through the boom. 

 Completely drain the spray system, remove nozzle tips and strainers and clean them separately.

Weed Management

Repeated use of herbicides with the same mode of action can lead to selection for resistant biotypes 

within the larger population of weeds. The key to controlling existing resistant weeds and slowing the 

development of new resistant weeds is to diversify and reduce selection pressure on the weed population 

while still maintaining high levels of weed control that limit weed seed production. 

Diversification of weed management strategies can be accomplished by integrating several proven 

practices for weed control, such as:

 Rotate crops and cultural practices to allow for a wider range of weed control practices.

 Start with a clean field, using either a burn-down herbicide application or tillage and scout fields 

before and after herbicide application.

 Use the correct herbicide product at the right rate and time and apply herbicide mixtures with 

different modes of action.

 Control weeds early when they are relatively small. Rotate herbicides that have different modes 

of action and use residual herbicides that have different modes of action.

 Use new commercial, weed-free crop seed and clean equipment before moving from field to field 

to minimize spread of weed seed.

 Control weed escapes and prevent weeds from setting seeds. Incorporate other herbicides and 

cultural practices as part of the herbicide-tolerant cropping systems where appropriate.
DRAFT—NOT FOR FURTHER DISTRIBUTION

Resources

 Enlist website: Enlist.com

 Trait Regulatory and Market Status: biotradestatus.com

 Trait Stewardship: traitstewardship.com

 Weed Resistance Assessment Tool: weedtool.com/

 Weed Resistance Management Training: soygrowers.com/WRM/default.htm

Contact Us

If you have questions about proper handling and use of these products or if you become aware of 

potential misuse or incidents involving these products, please call 877-4-TRAITS (877-487-2487).

Stewardship

Dow AgroSciences is a founding member of Excellence through Stewardship®and is a Responsible 

Care® Company.

 

Patent Statement 

This Seed is protected under one or more U.S. patents. Grower is provided a limited license under the Technology Use 

Agreement to purchase Seed from Seed Seller and to plant Purchased Seed to produce a single commercial crop in the United 

States. Grower is NOT permitted: (1) to supply, transfer, license or sublicense any Seed or Dow AgroSciences’ Sourced 

Technology to any other person, entity or other third party for planting or any other purposes; (2) to save or use any seed 

produced from Seed for planting by Grower or any other third party; or (3) to use or allow others to use Seed or any plant 

material produced from Seed for crop breeding, seed production, research (including, without limitation, agronomic testing or

generation of comparative data against seed containing Third-Party Trait Technology), or generation of regulatory approval 

data. 

Trademark Statement

®TMColex-D, Enlist, Enlist Duo and SmartStax are trademarks of The Dow Chemical Company (“Dow”) or an affiliated company 

of Dow. ®The Roundup Ready Corn 2 Logo is a registered trademark of Monsanto Technology LLC. ®Select Max is a 

registered trademark of Valent U.S.A. Corporation. ®Assure is a registered trademark of DuPont. ®Poast Plus is a registered 

trademark of BASF. Always follow weed resistance management, grain marketing and all other stewardship practices 

and pesticide label directions. Enlist corn contains genes that confer tolerance to 2,4-D, glyphosate, and quizalofop. 

Roundup Ready crops contain genes that confer tolerance to glyphosate herbicides. Glyphosate herbicides will kill crops that 

are not tolerant to glyphosate. Bt products may not yet be registered in all states. Check with your seed representative for the 

registration status in your state. ®Excellence Through Stewardship is a registered trademark of Excellence Through 

Stewardship. 

®Responsible Care is a registered service mark of the American Chemistry Council. Enlist Duo and Enlist Corn

have not yet received regulatory approvals; approvals are pending. Assure II amended label approval is pending. The

information presented is not an offer for sale. Always read and follow label directions.