Docket Number: EPA-HQ-OPP-2006-0111 

www.regulations.gov

Fenoxycarb 

Proposed Registration Review Final Decision 

February 2011 

TABLE OF CONTENTS 

I. INTRODUCTION........................................................................................4

II. BACKGROUND INFORMATION ...........................................................5 

III. PROPOSED REGISTRATION REVIEW FINAL DECISION ..............6 

IV. NEXT STEPS AND TIMELINE ................................................................6

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I. INTRODUCTION 

This document is the Environmental Protection Agency’s (EPA or the Agency) 

Proposed Registration Review Final Decision for fenoxycarb and is being issued 

pursuant to 40 CFR § 155.57 and § 155.58. A registration review decision is the 

Agency’s determination whether a pesticide meets, or does not meet, the standard for 

registration in the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). 

 FIFRA, as amended by the Food Quality Protection Act (FQPA) of 1996, 

mandated the continuous review of existing pesticides. All pesticides distributed or sold 

in the United States must generally be registered by EPA, based on scientific data 

showing that they will not cause unreasonable risks to human health or the environment 

when used as directed on product labeling. The registration review program is intended 

to make sure that, as the ability to assess risk evolves and as policies and practices 

change, all registered pesticides continue to meet the statutory standard of no 

unreasonable adverse effects to human health or the environment. Through the 

registration review program, the Agency periodically reevaluates pesticides to make sure 

that as change occurs, products in the marketplace can be safely used. Information on 

this program is provided at: http://www.epa.gov/oppsrrd1/registration_review/. 

In 2006, the Agency implemented the Registration Review program pursuant to 

FIFRA Section 3(g), and will review each registered pesticide every 15 years to 

determine whether it continues to meet the FIFRA standard for registration. 

 Pursuant to 40 CFR § 155.50, the Agency formally initiated registration review 

for fenoxycarb (case 7401). The following timeline highlights significant events that 

have occurred during the registration review of fenoxycarb: 

• August 1, 2007 – Publication of the Fenoxycarb Summary Document, Scoping 

Document, and Problem Formulation Document in the docket (EPA-HQ-OPP2006-0111) for a 60-day public comment period. The Summary Document also 

included the preliminary work plan. 

• December 20, 2007 – Publication of the Fenoxycarb Final Work Plan and the 

Agency’s response to the public comments received during the 60-day comment 

period on the fenoxycarb Summary Document. Based on the public comments 

received, the Fenoxycarb Final Work Plan was slightly modified from the 

Fenoxycarb Preliminary Work Plan. 

• August 25, 2010 – Published a Notice of Receipt of requests to voluntarily cancel 

certain pesticide registrations containing fenoxycarb in the Federal Register (75 

FR 52340) (FRL-8843-1). No comments were received during the 30-day 

comment period. 

• December 30, 2010 – Published the Product Cancellation Order for certain 

pesticide registrations containing fenoxycarb in the Federal Register (75 FR 

82387) (FRL-8854-8). 

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II. BACKGROUND INFORMATION 

Fenoxycarb is an O-ethyl carbamate ester derivative insecticide, miticide, insect 

growth regulator, sex attractant, or feeding stimulant. It is intended to be used to inhibit 

metamorphosis of juvenile insects to the adult stage. Fenoxycarb’s registered uses are all 

non-food uses. The registered use pattern is for indoor residential settings (flea control), 

greenhouses, turf (residential/commercial/ornamental), non-bearing orchards, and on 

outdoor plants. The most recent human health exposure assessments and environmental 

fate and ecological review occurred in the late 1990’s. 

 After the Final Work Plan was published in December, 2007 as part of the 

registration review process for fenoxycarb, the technical and end-use product registrants, 

Syngenta Crop Protection, Inc. and Whitmire Micro-Gen Research Laboratories, Inc. 

informed the Agency that they were each requesting to voluntarily cancel all of their 

fenoxycarb product registrations. A Notice of Receipt of requests to voluntarily cancel 

all pesticide registrations containing fenoxycarb published in the Federal Register on 

August 25, 2010. There were no comments submitted during the 30-day comment 

period. The Agency then issued the product cancellation order on December 30, 2010 

for all fenoxycarb product registrations. (Copies of those documents are included in the 

docket for this registration review.) As specified in the Cancellation Order, the 

fenoxycarb technical product and Whitmire Micro-Gen Research Laboratories, Inc.’s 

end-use product were cancelled as of December 30, 2010. 

 

Syngenta Crop Protection, Inc. is prohibited from using, selling, or distributing technical 

fenoxycarb except for: 

1. export consistent with FIFRA section 17 

2. for proper disposal, or 

3. to formulate existing stocks of the technical fenoxycarb into its end-use product 

effective immediately. 

The Syngenta Crop Protection Inc.’s end-use product is cancelled effective as of 

December 31, 2012. After December 31, 2012, Syngenta Crop Protection, Inc. is 

prohibited from selling or distributing its end-use product, except for export consistent 

with FIFRA section 17 or for proper disposal. Persons other than Syngenta Crop 

Protection, Inc. are allowed to sell, distribute, and use existing stocks of the canceled enduse product until supplies are exhausted, provided that such sale, distribution, and use is 

consistent with the terms of the previously approved labeling on, or that accompanied, 

the canceled product. 

Whitmire Micro-Gen Research Laboratories, Inc. is permitted to sell and 

distribute existing stocks of its end-use fenoxycarb product until December 31, 2013. 

Thereafter, Whitmire Micro-Gen Research Laboratories, Inc. is prohibited from selling or 

distributing its end-use product, except for export consistent with FIFRA section 17 or for 

proper disposal. Persons other than Whitmire Micro-Gen Research Laboratories, Inc. are 

allowed to sell, distribute, and use existing stocks of the canceled end-use product until 

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supplies are exhausted, provided that such sale, distribution, and use is consistent with the 

terms of the previously approved labeling on, or that accompanied, the canceled product. 

 

III. PROPOSED REGISTRATION REVIEW FINAL DECISION 

As stated in the Fenoxycarb Preliminary Work Plan, the Agency had intended to 

revise the existing risk assessments for fenoxycarb. However, due to the cancellation 

order issued affecting all remaining fenoxycarb product registrations in the United States, 

the Agency has found that it is not necessary to conduct new risk assessments for 

fenoxycarb and is, therefore, issuing a proposed decision pursuant to 40 CFR Part 

155.53(c)(2) and 40 CFR Part 155.58. The voluntary cancellation of all U.S. fenoxycarb 

registrations will become effective prior to the previously planned completion dates for 

the preliminary fenoxycarb risk assessments. Additionally, the sale and distribution of 

existing stock for the one remaining end use product will end in the same calendar year as 

the scheduled final registration review decision. The Registration Review Timeline 

introduced in the fenoxycarb preliminary work plan proposed that the Agency would 

issue the preliminary risk assessments in mid-2012, issue the revised risk assessments in 

late 2012 with a final registration review decision scheduled for 2013. 

The Agency does not expect the current risks associated with fenoxycarb use to 

differ from those identified during the fenoxycarb reregistration process. The existing 

stocks sales and distribution deadlines included in the December 30, 2010 cancellation 

order ensure that fenoxycarb sale, distribution, and use will decline and eventually cease 

entirely in the United States in the future. During this interim period, the Agency 

believes that existing stocks of fenoxycarb products may be used until depleted without 

causing unreasonable risk to human health and the environment. Pursuant to 40 CFR § 

155.57 and 155.58, the Agency proposes that the registration review final decision be 

issued, thus concluding the fenoxycarb registration review for the reasons discussed 

above. The affected product registrations are subject to the terms and conditions of the 

December 30, 2010 cancellation order. 

IV. NEXT STEPS AND TIMELINE 

Pursuant to 40 CFR § 155.58, this proposed registration review final decision 

document is being entered into the fenoxycarb docket (EPA-HQ-OPP-2006-0111). A 

Federal Register notice will announce the availability of this proposed registration 

review final decision for fenoxycarb and allow a 60-day comment period. If there are no 

significant comments or additional information submitted to the docket during the 

comment period that leads the Agency to change its decision, EPA will issue a 

registration review final decision for fenoxycarb (case 7401), which will be announced in 

the Federal Register. The Agency anticipates that the final decision will be issued in 

2011.