<PAGE>
 
                                   FORM 10-Q


                      SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, D.C. 20549
                                        
(MARK ONE)
   [X]  QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (D) OF THE SECURITIES
        EXCHANGE ACT OF 1934.
                 For the quarterly period ended  March 31, 1999
                                       OR
   [_]  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES
        EXCHANGE ACT OF 1934

For the transition period from _____ to _____

                        Commission file number 0-27750
                                    -------
                                  IMPATH INC.
            (exact name of registrant as specified in its charter)

<TABLE>
   <S>                                <C>                              <C>
            DELAWARE                              8071                    13-3459685
   (State or other jurisdiction of    (Primary Standard Industrial     (I.R.S. Employer
   incorporation or organization)      Classification Code Number)     Identification No.)
</TABLE>

                             521 West 57th Street
                           NEW YORK, NEW YORK 10019
                                (212) 698-0300
              (Address, including zip code, and telephone number,
       including area code, of registrant's principal executive offices)


Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such shorter period that the registrant was
required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days.

Yes    X    No______
     -----

     Indicate the number of shares outstanding of each of the issuer's classes
of common stock, as of the latest practicable date.


CLASS                              OUTSTANDING AT MARCH 31, 1999
-----                              -----------------------------
Common Stock, par value                      7,960,816
$  .005 per share

                                       1
<PAGE>
 
                                     INDEX

                         IMPATH INC. AND SUBSIDIARIES


<TABLE> 
<CAPTION> 
                                                                           PAGE NUMBER
                                                                           -----------
<S>                                                                        <C>          
Item 1.  Consolidated Financial Statements (Unaudited): 

                                                                                        
         Consolidated Balance Sheets at March 31, 1999
         and December 31, 1998............................................    3        
                                                                                       
         Consolidated Statements of Operations for the Three                           
         Months Ended March 31, 1999 and March 31, 1998...................    4        
                                                                                       
         Consolidated Statement of Stockholders' Equity for the                        
         Three Months Ended March 31, 1999................................    5        
                                                                                       
         Consolidated Statements of Cash Flows for the Three                           
         Months Ended March 31, 1999 and March 31, 1998...................    6        
                                                                                       
                                                                                       
         Notes to Consolidated Financial Statements.......................    7-9      
                                                                                       
Item 2.  Management's Discussion and Analysis                                          
of Financial Condition and Results of Operations..........................    10-12    
                                                                                       
Item 3.  Quantitative and Qualitative Disclosures about Market Risk.......    13       
                                                                                       
Signatures................................................................    14
</TABLE> 
         

                                       2
<PAGE>
 
            Item 1.  Consolidated Financial Statements (Unaudited)

                         IMPATH INC. AND SUBSIDIARIES

                          Consolidated Balance Sheets
                                  (unaudited)

<TABLE>
<CAPTION>
                                                                  MARCH 31,            DEC. 31,  
                                                                    1999                 1998    
                            ASSETS                              -----------          ----------- 
<S>                                                             <C>                  <C>          
Current assets:
 Cash and cash equivalents                                      $ 26,513,759         $ 45,556,005
 Marketable securities, at market value                           30,610,800           29,971,456
 Accounts receivable, net of allowance for doubtful accounts      23,178,529           19,619,451
 Prepaid expenses                                                    705,706              442,480
 Prepaid taxes                                                       575,798            1,758,407
 Deferred tax assets, net                                          1,334,591            1,334,591
 Other current assets                                              1,999,919            1,306,653
                                                                ------------         ------------
 Total current assets                                             84,919,102           99,989,043
 
Fixed assets, less accumulated depreciation and amortization      21,838,297           21,239,884
Deposits and other assets                                            203,491              203,491
Intangible assets, net of accumulated amortization                28,160,343           28,600,749
                                                                ------------         ------------
 Total assets                                                   $135,121,233         $150,033,167
                                                                ============         ============
 
               LIABILITIES AND STOCKHOLDERS' EQUITY
 
Current liabilities:
 Current portion of capital lease obligations                   $  1,394,057         $  1,622,366
 Current portion of note payable                                     962,915            1,271,915
 Short term borrowings                                             2,000,000           10,000,000
 Accounts payable                                                  2,148,539            2,713,228
 Deferred revenue                                                  1,943,126            1,866,241
 Accrued expenses                                                  1,467,964            1,819,752
                                                                ------------         ------------
  Total current liabilities                                        9,916,601           19,293,502
                                                                ------------         ------------
Capital lease obligations, net of current portion                  4,394,603            3,792,833
Note payable, net of current portion                                 183,333              233,333
Deferred tax payable                                               2,126,531            2,126,531
 
Stockholders' equity:
 Common stock                                                         42,953               42,690
 Additional paid-in capital                                      121,100,151          120,904,861
 Retained earnings                                                13,885,685           12,095,622
 Accumulated other comprehensive (loss)                             (112,590)             (48,602)
                                                                ------------         ------------
                                                                 134,916,199          132,994,571
 
Less:
 Cost of 630,038 and 313,688 shares of common stock
   held in treasury in 1999 and 1998, respectively               (15,976,552)          (7,908,841)
 Deferred compensation                                              (439,482)            (498,762)
                                                                ------------         ------------
 Total stockholders' equity                                      118,500,165          124,586,968
                                                                ------------         ------------
 Total liabilities and stockholders' equity                     $135,121,233         $150,033,167
                                                                ============         ============
</TABLE>

See accompanying notes to consolidated financial statements.

                                       3
<PAGE>
 
                         IMPATH INC. AND SUBSIDIARIES

                     Consolidated Statements of Operations
                                  (Unaudited)

<TABLE>
<CAPTION>
                                                         THREE MONTHS ENDED MARCH 31,
                                                        ------------------------------
                                                             1999            1998
                                                        --------------  --------------
<S>                                                     <C>             <C>
Revenues:
 Net diagnostic and prognostic services                 $  15,733,966   $  11,603,161
 Biopharmaceutical services                                   252,054         109,347
 Tumor registry services                                      984,131               -
                                                        -------------   -------------
  Total revenues                                           16,970,151      11,712,508
                                                        -------------   -------------    

Operating expenses:
 Salaries and related costs                                 6,727,322       4,729,622
 Selling, general and administrative                        6,357,057       4,728,647
 Depreciation and amortization                              1,362,453         553,457
                                                        -------------   -------------
  Total operating expenses                                 14,446,832      10,011,726
                                                        -------------   -------------
    Income from operations                                  2,523,319       1,700,782
 
Interest income                                               670,898         341,138
Interest expense                                             (171,154)       (133,109)
                                                        -------------   -------------
 
    Income before income tax expense                        3,023,063       1,908,811
 
Income tax expense                                         (1,233,000)       (830,660)
                                                        -------------   -------------
Net income                                              $   1,790,063   $   1,078,151
                                                        =============   =============
 
 
Per common and common equivalent share:
Basic:
 Net income per common share                            $         .22   $         .18
                                                        =============   =============
 Weighted average common and common
 equivalent shares outstanding                              8,041,000       6,011,000
                                                        =============   =============
Diluted:
 
 Net income per common share-assuming dilution          $         .22   $         .17
                                                        =============   =============    
 Weighted average common and common
 equivalent shares outstanding-assuming dilution            8,278,000       6,460,000
                                                        =============   =============
</TABLE>

See accompanying notes to consolidated financial statements.

                                       4
<PAGE>
 
                         IMPATH INC. AND SUBSIDIARIES

                Consolidated Statement of Stockholders' Equity
                       Three Months ended March 31, 1999
                                  (Unaudited)

<TABLE>
<CAPTION>      
                                                                                   ACCUMULATED                               
                                                      ADDITIONAL                       OTHER                                 
                                    COMMON STOCK       PAID-IN         RETAINED    COMPREHENSIVE   TREASURY       DEFERRED   
                                --------------------                                                                         
                                 SHARES      AMOUNT    CAPITAL         EARNINGS       (LOSS)        STOCK       COMPENSATION 
                                --------   ---------  ---------      -----------  --------------  ---------   ---------------
<S>                             <C>        <C>        <C>            <C>          <C>             <C>         <C>            
Balance at December 31, 1998    8,538,345  $  42,690  $120,904,861   $ 12,095,622    ($48,602)    ($7,908,841)  ($498,762)  
                                                                                                                             
Common shares issued upon                                                                                                    
 exercise of stock options         52,296        262       194,546                                                           
Common shares issued                                                                                                         
 upon exercise of warrants            213          1           744
Repurchase of common shares                                                                        (8,067,711)               
Amortization of deferred
 compensation                                                                                                      59,280 
Comprehensive income(loss): 
Change in accumulated
 comprehensive (loss)                                                                 (63,988)
Net income for the period
 ended March 31, 1999                                                   1,790,063
      
                                ---------   --------  ------------   ------------   ---------    ------------   ---------   
Total comprehensive income                                                                                                   
 
                                ---------   --------  ------------   ------------   ---------    ------------   ---------   
Balance at March 31, 1999       8,590,854   $ 42,953  $121,100,151   $ 13,885,685   ($112,590)   ($15,976,552)  ($439,482)  
                                =========   ========  ============   ============   =========    ============   =========

<CAPTION> 
                                     TOTAL 
                                  ------------     
<S>                               <C>           
Balance at December 31, 1998      $124,586,968
 
Common shares issued upon            
 exercise of stock options             194,808
      
Common shares issued                                                                                                            
 upon exercise of warrants                 745 
      
Repurchase of common shares         (8,067,711)                       
Amortization of deferred            
 compensation                           59,280 
Comprehensive income(loss): 
Change in accumulated
 comprehensive (loss)                  (63,988)
Net income for the period
 ended March 31, 1999                1,790,063
                             
                                  ------------   
Total comprehensive income           1,726,075   
                               
                                  ------------
Balance at March 31, 1999         $118,500,165
                                  ============
</TABLE> 

See accompanying notes to consolidated financial statements.

                                       5
<PAGE>
 
                         IMPATH INC. AND SUBSIDIARIES
                                        
                     Consolidated Statements of Cash Flows
                                  (Unaudited)

<TABLE> 
<CAPTION> 

                                                                            THREE MONTHS ENDED MARCH 31,
                                                                            ----------------------------
                                                                                  1999          1998
                                                                            ----------------------------
Cash flows from operating activities:
<S>                                                                          <C>            <C>
   Net income                                                                $  1,790,063     1,078,151
    Adjustments to reconcile net income to net cash provided by (used in)
    operating activities:
    Depreciation and amortization                                               1,362,453       553,457
    Provision for uncollectible accounts receivable                             1,745,066     1,163,396
    Non-cash compensation                                                          59,280        70,733
         Changes in assets and liabilities:
         (Increase) in accounts receivable                                     (5,304,145)   (2,974,760)
         Decrease in prepaid taxes                                              1,182,609       534,984
         (Increase) in prepaid expenses and current assets                       (956,492)     (212,665)
         Decrease in deposits and other assets                                          -       154,133
         (Decrease) in accounts payable and accrued expenses                     (916,477)     (100,780)
 
         Increase in deferred revenue                                              76,885             -
                                                                             ------------   -----------
       Total adjustments                                                       (2,750,821)     (811,502)
                                                                             ------------   -----------
Net cash (used in) provided by operating activities                              (960,758)      266,649
                                                                             ------------   -----------
Cash flows from investing activities:
    Purchases of marketable securities                                        (21,206,789)   (7,273,339)
    Sales/maturities of marketable securities                                  20,503,457     3,611,792
    Capital expenditures                                                         (628,790)   (2,307,550)
                                                                             ------------   -----------
Net cash (used in) investing activities                                        (1,332,122)   (5,969,097)
                                                                             ------------   -----------
Cash flows from financing activities:
  Issuance of common stock                                                        195,553       194,098
  Repurchase of common stock                                                   (8,067,711)            -
  Proceeds of secondary offering, net of registration costs                             -    71,716,311
  Payments of capital lease obligations                                          (465,308)     (324,806)
  (Repayment) of bank loans, net                                               (8,000,000)            -
  Payments of Notes Payable                                                      (411,900)            -
                                                                             ------------   -----------
Net cash (used in) provided by financing activities                           (16,749,366)   71,585,603
                                                                             ------------   -----------
Net (decrease) increase in cash and cash equivalents                          (19,042,246)   65,883,155
Cash and cash equivalents at beginning of period                               45,556,005       325,285
                                                                             ------------   -----------
Cash and cash equivalents at end of period                                   $ 26,513,759   $66,208,440
                                                                             ============   ===========
</TABLE>

See accompanying notes to consolidated financial statements.

                                       6
<PAGE>
 
                                  IMPATH INC.
                                        
                  Notes to Consolidated Financial Statements
                                  (unaudited)

GENERAL:

The accompanying unaudited consolidated financial statements have been prepared
by management in accordance with the rules and regulations of the United States
Securities and Exchange Commission.

In the opinion of IMPATH Inc. (the "Company" or "IMPATH"), the accompanying
unaudited consolidated financial statements contain all adjustments, consisting
only of normal recurring adjustments necessary for the fair presentation of the
financial information for all periods presented. Results for the interim periods
are not necessarily indicative of the results for an entire year and do not
include all of the information and footnotes required by generally accepted
accounting principles for complete financial statements. These consolidated
financial statements should be read in conjunction with the consolidated
financial statements and the notes thereto contained in the Company's Annual
Report on Form 10-K for the year ended December 31, 1998.

NET INCOME PER SHARE:

Net income per share, basic is based on the weighted average number of shares of
common stock outstanding.  Diluted earnings per share is based on the weighted
average number of shares of common stock and common equivalent shares
outstanding.  Common equivalent shares from stock options and warrants are
included in the computation assuming the related options and warrants had been
exercised to the extent their effect is dilutive.

Comprehensive net income is equal to the net income reported adjusted for the
unrealized net depreciation of marketable securities, net of related deferred
taxes.  Comprehensive net income for the three months ended March 31, 1999 and
1998 was $1,726,075 and $1,124,463, respectively.

INVESTMENT:

In accordance with Statement of Financial Accounting Standards ("SFAS") No. 115,
the Company's investments (consisting primarily of government and corporate
fixed income securities) were classified as available for sale.  As a result,
the unrealized depreciation is recorded as a separate component of stockholders'
equity, net of related deferred taxes.  At March 31, 1999, approximately
$27,000,000 of securities with original maturities of  three months or less were
included as cash equivalents.  The remaining securities included in the
investment portfolio with original maturities that exceed three months are
included in current assets.

                                       7
<PAGE>
 
ACCOUNTS RECEIVABLE, NET OF ALLOWANCE FOR DOUBTFUL ACCOUNTS:

In accordance with Generally Accepted Accounting Principles ("GAAP") and
consistent with healthcare industry practices, IMPATH presents its accounts
receivable at net realizable value.  Net accounts receivable balances are
comprised of the following as of March 31, 1999 and December 31, 1998:


<TABLE>
<CAPTION>
                                          March 31, 1999     December 31, 1998
                                        ------------------ ---------------------
<S>                                     <C>                 <C>
Gross accounts receivable ............     $ 41,289,863       $ 35,138,046
Allowance for doubtful accounts ......       (3,745,878)        (3,958,235)
Contractual allowance reserve ........      (14,365,456)       (11,560,360)
                                            ------------       ------------
                                            $ 23,178,529       $ 19,619,451
                                            ============       ============
</TABLE>
                                                                                

The growth in the contractual allowance reserve (contractual allowances are
provided against revenues) is due to the increasing shift to managed care
contracts from traditional fee for service billing.

RECENT ACQUISITIONS

On July 29, 1998 the Company purchased certain assets of Biologic & Immunologic
Science Laboratories, Inc. ("BIS"), a privately held cancer diagnostics company
based in Reseda, California for $3.6 million. The terms provided for an initial
payment of $2.0 million, and $800,000 payable in three equal semi-annual
installments beginning December 1998, after which another $800,000 is payable in
three equal semi-annual installments contingent on achievement of previously
established revenue targets, with interest accruing at 8% per annum. This
transaction will allow IMPATH to expand its core diagnostic and prognostic
business and build on IMPATH's scientific leadership in lymph node and bone
marrow micrometastases detection in early and late stage cancer. Additionally,
BIS will further enhance the Company's ability to provide unique cancer
information to physicians for evaluating and treating cancer patients and to the
biopharmaceutical industry in assessing biologically relevant characteristics
for targeted drug development and in selecting patients for clinical trials and
in evaluating the efficacy of various therapies.

On August 31, 1998 the Company acquired Medical Registry Services, Inc. ("MRS")
for the issuance of  550,000 shares of IMPATH common stock valued at
$13,750,000.  After the consideration of certain other expenses related to the
acquisition and after recording net tangible assets of MRS, the Company recorded
approximately $17.3 million in intangibles.  MRS is a leading developer and
marketer of cancer registry software products that are currently utilized in
over 400 hospitals throughout the United States.  The products are used to
collect and manage critical diagnostic, treatment, follow-up and outcomes data
on cancer patients.  The Company and MRS, which at the time of the acquisition
had approximately 200 common clients, began a relationship through a strategic
joint venture in January, 1997.  The acquisition of MRS significantly enhances
IMPATH's oncology information capabilities by matching its diagnostic and
prognostic data with treatment and outcomes information from MRS.  Additionally,
it provides IMPATH with an ongoing link to its clients as its ability to supply
hospitals and oncologists with critical information for optimal disease
management will continue to expand.  MRS's revenues are derived from licensing
fees paid by hospitals utilizing its proprietary tumor registry software.

On September 2, 1998 the Company acquired Physician Choice, Inc.  ("PCI") for
the sum of $1.0 million, with $400,000 payable immediately, an additional
$400,000 payable in four equal semi-annual installments beginning March, 1999
with interest accruing at 8% per annum and $200,000 payable in IMPATH common
stock.  An initial 1,980 shares of common stock, having a fair market value of
$50,000, were issued on September 2, 1998, with the remaining shares to be
issued in three equal annual installments beginning September 2, 1999.  PCI is a
leading provider of post-clinical, pre-marketing, cost-benefit analyses to
pharmaceutical and biotechnology companies in connection with new oncology drugs
entering the marketplace.  By focusing on cancer, and utilizing health care
outcomes and other efficacy measures, PCI has achieved a better understanding of
the way healthcare is delivered in that specialty.  PCI's revenues are generated
on a per project basis from pharmaceutical and biotechnology companies.

                                       8
<PAGE>
 
The aforementioned acquisitions have been accounted for using the purchase
method with results of operations of the respective entities being included with
the results of the Company since the respective acquisition dates.

The excess of the purchase price over the net assets acquired on both the BIS
and PCI acquisitions principally relate to customer lists, which are included in
intangible assets on the Company's consolidated balance sheet and are being
amortized over periods of up to fifteen years. The excess of the purchase price
over the net assets acquired for the MRS purchase primarily relates to the
customer list, trade name, software and goodwill which are included in
intangible assets on the accompanying balance sheets and are being amortized
over periods of 5 to 20 years.

                                       9
<PAGE>
 
                 ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS
               OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS
                                        

                       THREE MONTHS ENDED MARCH 31, 1999
                COMPARED WITH THREE MONTHS ENDED MARCH 31, 1998

The Company's total revenues for the first three months of 1999 and 1998 were
$16,970,000 and $11,713,000, respectively, representing an increase of
$5,257,000, or 44.9%, in 1999.  This growth was primarily attributable to a
26.3% increase in case volume resulting from increased sales and marketing
activities, and increased contract services provided to biopharmaceutical
companies.  In addition, the Company recorded revenues of $984,000 from tumor
registry services relating to the 1998 acquisition of Medical Registry Services.
Additionally, revenue realization per case increased due to product mix changes
toward cases which carry higher reimbursement rates and to payor mix shifts away
from direct hospital billing towards private insurance.

Salaries and related costs for the first three months of 1999 and 1998 were
$6,727,000 and $4,730,000, respectively, representing an increase of $1,997,000,
or 42.2%, in 1999.  This increase was the result of increased personnel
headcount due to the increase in case volume, as well as personnel costs
incurred in connection with the Company's acquisitions.  As a percentage of
total revenues, salaries and related costs decreased to 39.6% in 1999 from 40.4%
in 1998.  This decrease was facilitated by the Company's successful expansion
strategy of incorporating complementary and synergistic technologies, as well as
streamlining operational and administrative duties.

Selling, general and administrative expenses for the first three months of 1999
and 1998 were $6,357,000 and $4,729,000, respectively, representing an increase
of $1,628,000, or 33.9%, in 1999. The largest component of this increase was
$642,000 in incremental courier and laboratory supply costs due to increased
case volume growth.  The Company also incurred an additional $582,000 of
increased bad debt expense associated with increased revenues.  Additionally,
$263,000 of the increase was a result of increased operating expenses incurred
in connection with the Company's acquisitions.  In addition, the Company
incurred $109,000 in incremental travel related expenses associated with
expanded sales, marketing and investor relations activities.  As a percentage of
total revenues, selling, general and administrative expenses decreased to 37.5%
in 1999 from 40.5% in 1998 due to the implementation of certain operating
efficiencies combined with higher revenue realization per case.

Depreciation and amortization expense for the first three months of 1999 and
1998 was $1,362,000 and $553,000, respectively, representing an increase of
$809,000, or 146.3%, in 1999.  This increase was primarily due to an additional
$322,000 in amortization of intangible assets associated with the Company's 1998
acquisitions.  The Company also incurred an additional $283,000 in depreciation
and amortization expense associated with increased capital equipment
requirements.  As a percentage of total revenues, depreciation and amortization
increased to 8.0% in 1999 from 4.7% in 1998.

Income from operations for the first three months of 1999 and 1998 was
$2,523,000 and $1,701,000, respectively, representing an increase of $822,000,
or 48.3%, in 1999.  The 1999 figure reflects an increase in company operating
margins from its core diagnostic and prognostic services and recent acquisitions
partially mitigated by increased depreciation and amortization. As a percentage
of total revenues, income from operations increased to 14.9% in 1999 from 14.5%
in 1998.

Other income, net for the first three months of 1999 and 1998 was $500,000 and
$208,000, respectively, representing an increase of $292,000, or 140.4%, in
1999. The increase was the result of increased interest income generated from
the proceeds of the Company's follow on public offering of common stock in March
1998, partially offset by increased interest expense primarily due to additional
capital lease obligations and acquisition-related debt.

                                       10
<PAGE>
 
The tax provision for the first three months of 1999 of $1,233,000 reflects
federal, state and local income tax expense. The Company has estimated its
annual effective tax rate for 1999 to be approximately 41.0%, as compared to
39.7% in 1998.

Net income for the first three months of 1999 and 1998 was $1,790,000 and
$1,078,000, respectively, representing an increase of  $712,000, or 66.0%, in
1999.  As a percentage of total revenues, net income increased to 10.5% in 1999
from 9.2% in 1998, due to the factors described above.

LIQUIDITY AND CAPITAL RESOURCES

Since inception, the Company has financed its operations through public
offerings of common stock, the private issuance of convertible preferred stock,
secured term loans and operating and capital equipment leases.   The Company's
working capital and capital expenditures needs have increased and are expected
to continue to increase as the Company expands its existing facilities and
pursues its growth strategy.

The Company's cash and cash equivalent balances at March 31, 1999 and December
31, 1998 were $26,514,000 and $45,556,000, respectively, representing a decrease
of $19,042,000 in 1999.  This decrease was primarily due to the repayment of
short term line of credit bank borrowings of $8,000,000 and the repurchase by
the Company of common stock for approximately $8,068,000 under the share buyback
program that was initiated in December 1998.

For the quarter ended March 31, 1999, net cash used in operating activities was
approximately $961,000.  This was primarily due to an increase in accounts
receivable net of allowance for bad debt of approximately $3,559,000.  The
increase in net accounts receivable was due to rapid sales growth and the
continuing shift away from direct hospital billing and towards private insurance
which carries a higher revenue realization per case, as well as the additional
time required to retrieve patient specific information.  In addition, as a
result of increased case volume growth and the introduction of several new
products, laboratory supplies included in other current assets increased
approximately $454,000.  The Company also reduced its accounts payable and
accrued expenses by approximately $916,000.  These activities were partially
offset by higher net income, as well as an increase in income taxes payable of
$1,183,000.

For the three months ended March 31, 1999, the Company invested approximately
$703,000 of the proceeds from the follow on offering in marketable securities,
resulting in a balance of approximately $30,611,000 of marketable securities at
March 31, 1999.  Additionally, the Company incurred approximately $629,000 in
capital expenditures associated with the development of the Company's outcomes
database and network infrastructure.

The Company received approximately $196,000 for the quarter ended March 31, 1999
through the issuance of Common Stock upon the exercise of Company stock options
and warrants.  The Company used approximately $465,000 to satisfy its capital
lease obligations, and approximately $412,000 to meet its note obligations
resulting from its asset acquisitions.

In March 1998, the Company established an unsecured line of credit for an
aggregate principal amount of  $10,000,000 with Fleet Bank.  Borrowing under the
line bears interest at LIBOR plus 2.25%.  As of March 31, 1999, the Company had
$2,000,000 outstanding under this line.  The line of credit has certain
financial covenants which the Company was in compliance with at March 31, 1999.

The Company's growth strategy is anticipated to be financed through its current
cash resources and existing third-party credit facilities.  The Company believes
the combination of these sources will be sufficient to fund its operations and
satisfy the Company's cash requirements for the next 12 months and the
foreseeable future.  There may be circumstances, however, that would accelerate
the Company's use of proceeds from the follow on public offering.  If this
occurs, the Company may, from time to time, incur additional indebtedness or
issue, in public or private transactions, equity or debt securities.  However,
there can be no assurance that suitable debt or equity financing will be
available to the Company.

                                       11
<PAGE>
 
IMPACT OF INFLATION AND CHANGING PRICES

The impact of inflation and changing prices on the Company has been primarily
limited to salary, laboratory and operating supplies and rent increases and has
not been material to date to the Company's operations.  In the future, the
Company's revenue realization per case may not be sufficient to cover the cost
of inflation, although the Company is responding to these concerns by attempting
to increase the volume and adjust the product mix of its business.

YEAR 2000

The Company has reviewed its business systems, including its computer systems
and laboratory equipment, and has been sending written inquiries to its
customers and vendors as to their progress in identifying and addressing
problems that their systems may face in correctly interpreting and processing
date information as the year 2000 approaches.  This review was completed in
April 1999.  Based on this review, the Company will implement a plan to achieve
year 2000 compliance.  The Company is in the final stages of the installation of
a newly developed clinical and billing information system which addresses year
2000 issues.  The Company believes that it will achieve year 2000 compliance in
a manner which will be non-disruptive to its operations.  All businesses
acquired by the Company in 1998 are year 2000 compliant.  In addition, the
Company has commenced work on various types of contingency planning to address
potential problem areas with internal systems, suppliers and other third
parties.  Year 2000 compliance should not have a material adverse effect on the
Company, including the Company's financial condition, results of operations or
cash flow.  The Company has incurred no costs to date related to year 2000.  The
Company estimates the cost of its year 2000 efforts to be approximately
$150,000.  The total cost estimate is based on management's current assessment
and is subject to change.

However, the Company may encounter problems with supplier and or revenue sources
which could adversely affect the Company's financial condition, results of
operations or cash flow.  The Company cannot accurately predict the occurrence
and or outcome of any such problems, nor can the dollar amount of such problems
be estimated.  In addition, there can be no assurance that the failure to ensure
year 2000 compliance by a third party would not have a material adverse effect
on the Company.

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<PAGE>
 
     ITEM 3.   QUANTITATIVE AND QUALITATIVE  DISCLOSURES ABOUT MARKET RISK

The following discussion about our exposure to market risk of financial
instruments contains forward-looking statements.  Actual results may differ
materially from those described.

The Company's holdings of financial instruments are comprised of U.S. corporate
debt, U.S. government debt and commercial paper.  All such instruments are
classified as securities available for sale.  The Company does not invest in
portfolio equity securities or commodities or use financial derivatives for
trading purposes.  The Company's debt security portfolio represents funds held
temporarily pending use in our business and operations.  The Company manages
these funds accordingly.  The Company seeks reasonable assuredness of the safety
of principal and market liquidity by investing in rated fixed income securities
while at the same time seeking to achieve a favorable rate of return.  The
Company's market risk exposure consists principally of exposure to changes in
interest rates.  The Company's holdings are also exposed to the risks of changes
in the credit quality of issuers.  The Company typically invests in the shorter-
end of the maturity spectrum, and at December 31, 1998, more than 80% of the
Company's holdings were in instruments maturing in two years or less and more
than 65% of such holdings matured in one year or less.

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<PAGE>
 
                                  SIGNATURES


Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.



     Dated: May 14, 1999            IMPATH INC.
                                    -----------
                                    (Registrant)


     Dated: May 14, 1999            By   / s /  ANU D. SAAD
                                    ----------------------------  
                                    Anu D. Saad, Ph.D.
                                    President and Chief
                                    Executive Officer


     Dated: May 14, 1999            By / s / JOHN P. GANDOLFO
                                    ----------------------------
                                    John P. Gandolfo
                                    Executive Vice President,
                                    Chief Financial Officer,
                                    Chief Operating Officer,
                                    and Principal Accounting Officer

                                       14