# Patent

## Title
Method of profiling gene expression in a subject having alzheimer's disease

## Abstract

The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.

## Background
CROSS-REFERENCE TO RELATED APPLICATION
This application is a continuation of U.S. patent application Ser. No. 12/587,385, filed Oct. 5, 2009, which is a continuation of U.S. patent application Ser. No. 10/268,730 filed Oct. 9, 2002 now U.S. Pat. No. 7,598,031, which is a continuation of U.S. application Ser. No. 09/477,148 filed Jan. 4, 2000, which claims the benefit of U.S. Provisional Application No. 60/115,125 filed on Jan. 6, 1999. Each of these applications is incorporated herein by reference in their entirety, including the figures and drawings.


BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the molecular biology of human diseases. More specifically, the present invention relates to a process using the genetic information contained in human peripheral whole blood for the diagnosis, prognosis and monitoring of genetic and infectious disease in the human body.
2. Description of the Related Art
The blood is a vital part of the human circulatory system for the human body. Numerous cell types make up the blood tissue including monocytes, leukocytes, lymphocytes and erythrocytes. Although many blood cell types have been described, there are likely many as yet undiscovered cell types in the human blood. Some of these undiscovered cells may exist transiently, such as those derived from tissues and organs that are constantly interacting with the circulating blood in health and disease. Thus, the blood can provide an immediate picture of what is happening in the human body at any given time.
The turnover of cells in the hematopoietic system is enormous. It was reported that over one trillion cells, including 200 billion erythrocytes and 70 billion neutrophilic leukocytes, turn over each day in the human body (Ogawa 1993). As a consequence of continuous interactions between the blood and the body, genetic changes that occur within the cells or tissues of the body will trigger specific changes in gene expression within blood. It is the goal of the present invention that these genetic alterations be harnessed for diagnostic and prognostic purposes, which may lead to the development of therapeutics for ameliorating disease.
The complete profile of gene expression in the circulating blood remains totally unexplored. It is hypothesized that gene expression in the blood is reflective of body state and, as such, the resultant disruption of homeostasis under conditions of disease can be detected through analysis of transcripts differentially expressed in the blood alone. Thus, the identification of several key transcripts or genetic markers in blood will provide information about the genetic state of the cells, tissues, organ systems of the human body in health and disease.
The prior art is deficient in non-invasive methods of screening for tissue-specific diseases. The present invention fulfills this long-standing need and desire in the art.
SUMMARY OF THE INVENTION
This present invention discloses a process of using the genetic information contained in human peripheral whole blood in the diagnosis, prognosis and monitoring of genetic and infectious disease in the human body. The process described herein requires a simple blood sample and is, therefore, non-invasive compared to conventional practices used to detect tissue specific disease, such as biopsies.
One object of the present invention is to provide a non-invasive method for the diagnosis, prognosis and monitoring of genetic and infectious disease in humans and animals.
In one embodiment of the present invention, there is provided a method for detecting expression of a gene in blood from a subject, comprising the steps of: a) quantifying RNA from a subject blood sample; and b) detecting expression of the gene in the quantified RNA, wherein the expression of the gene in quantified RNA indicates the expression of the gene in the subject blood.
In another embodiment of the present invention, there is provided a method for detecting expression of one or more genes in blood from a subject, comprising the steps of: a) obtaining a subject blood sample; b) extracting RNA from the blood sample; c) amplifying the RNA; d) generating expressed sequence tags (ESTs) from the amplified RNA product; and e) detecting expression of the genes in the ESTs, wherein the expression of the genes in the ESTs indicates the expression of the genes in the subject blood. Preferably, the genes are tissue-specific genes.
In still another embodiment of the present invention, there is provided a method for detecting expression of one or more genes in blood from a subject, comprising the steps of: a) obtaining a subject blood sample; b) extracting DNA fragments from the blood sample; c) amplifying the DNA fragments; and d) detecting expression of the genes in the amplified DNA product, wherein the expression of the genes in the amplified DNA product indicates the expression of the genes in the subject blood.
In yet another embodiment of the present invention, there is provided a method for monitoring a course of a therapeutic treatment in an individual, comprising the steps of: a) obtaining a blood sample from the individual; b) extracting RNA from the blood sample; c) amplifying the RNA; d) generating expressed sequence tags (ESTs) from the amplified RNA product; e) detecting expression of genes in the ESTs, wherein the expression of the genes is associated with the effect of the therapeutic treatment; and f) repeating steps a)-e), wherein the course of the therapeutic treatment is monitored by detecting the change of expression of the genes in the ESTs. Such a method may also be used for monitoring the onset of overt symptoms of a disease, wherein the expression of the genes is associated with the onset of the symptoms.
In still yet another embodiment of the present invention, there is provided a method for diagnosing a disease in a test subject, comprising the steps of: a) generating a cDNA library for the disease from a whole blood sample from a normal subject; b) generating expressed sequence tag (EST) profile from the normal subject cDNA library; c) generating a cDNA library for the disease from a whole blood sample from a test subject; d) generating EST profile from the test subject cDNA library; and e) comparing the test subject EST profile to the normal subject EST profile, wherein if the test subject EST profile differs from the normal subject EST profile, the test subject might be diagnosed with the disease.
In still yet another embodiment of the present invention, there is provided a kit for diagnosing, prognosing or predicting a disease, comprising: a) gene-specific primers; wherein the primers are designed in such a way that their sequences contain the opposing ends of two adjacent exons for the specific gene with the intron sequence excluded; and b) a carrier, wherein the carrier immobilizes the primer(s). Such a kit may be applied to a test subject whole blood sample to diagnose, prognose or predict a disease.
In yet another embodiment of the present invention, there is provided a kit for diagnosing, prognosing or predicting a disease, comprising: a) probes derived from a whole blood sample for a specific disease; and b) a carrier, wherein the carrier immobilizes the probes. Such a kit may be applied to a test subject whole blood sample to diagnose, prognose or predict a disease.
Furthermore, the present invention provides a cDNA library specific for a disease, wherein the cDNA library is generated from whole blood samples.
Other and further aspects, features, and advantages of the present invention will be apparent from the following description of the presently preferred embodiments of the invention. These embodiments are given for the purpose of disclosure.



BRIEF DESCRIPTION OF THE DRAWINGS
So that the matter in which the above-recited features, advantages and objects of the invention, as well as others which will become clear, are attained and can be understood in detail, more particular descriptions of the invention briefly summarized above may be had by reference to certain embodiments thereof which are illustrated in the appended drawings. These drawings form a part of the specification. It is to be noted, however, that the appended drawings illustrate preferred embodiments of the invention and therefore are not to be considered limiting in their scope.not be considered to limit the scope of the invention.
FIG. 1 shows the following RNA samples prepared from human blood; FIG. 1A: Lane 1, Molecular weight marker; Lane 2, RT-PCR on APP gene; Lane 3, PCR on APP gene; Lane 4, RT-PCR on APC gene; Lane 5, PCR on APC gene; FIG. 1B: Lanes 1 and 2, RT-PCR and PCR of (MyHC, respectively; Lanes 3 and 4, RT-PCR of (MyHC from RNA prepared from human fetal and human adult heart, respectively; Lane 5, Molecular weight marker.
FIG. 2 shows quantitative RT-PCR analysis performed on RNA samples extracted from a drop of blood. Forward primer (5′-GCCCTCTGGGGACCTGAC-3′, SEQ ID No. 1) of exon 1 and reverse primer (5′-CCCACCTGCAGGTCCTCT-3′′, SEQ ID No. 2) of exons 1 and 2 of insulin gene. Blood samples of 4 normal subjects were assayed. Lanes 1, 3, 5 and 7 represent overnight “fasting” blood sample and lanes 2, 4, 6 and 8 represent “non-fasting” samples.
FIG. 3 shows quantitative RT-PCR analysis performed on RNA samples extracted from a drop of blood. Lanes 1 and 2 represent normal healthy person and lane 3 represents late-onset diabetes (Type II) and lane 4 represents asymptomatic diabetes.
FIG. 4 shows multiple RT-PCR assay in a drop of blood. Primers were derived from insulin gene (INS), zinc-finger protein gene (ZFP) and house-keeping gene (GADH). Lane 1 represents normal person. Lane 2 represents late-onset diabetes and lane 3 represents asymptomatic diabetes.
FIG. 5 shows standardized levels of insulin gene (FIG. 5A) and ZFP gene (FIG. 5B) expressed in a drop of blood. The first three subjects were normal, second two subjects showed normal glucose tolerance, and the last subject had late onset diabetes type II. FIG. 5C shows standardized levels of insulin gene expressed in each fractionated cell from whole blood.
FIG. 6 shows the differential screening of human blood cell cDNA library with different cDNA probes of heart and brain tissue. FIG. 6A shows blood cell cDNA probes vs. adult heart cDNA probes. FIG. 6B shows blood cell cDNA probes vs. human brain cDNA probes.
FIG. 7 graphically shows the 1,800 unique genes in human blood and in the human fetal heart grouped into seven cellular functions.



DETAILED DESCRIPTION OF THE INVENTION
In accordance with the present invention, there may be employed conventional molecular biology, microbiology, and recombinant DNA techniques within the skill of the art. Such techniques are explained fully in the literature. See, e.g., Sambrook, Fritsch & Maniatis, “Molecular Cloning: A Laboratory Manual (1982); “DNA Cloning: A Practical Approach,” Volumes I and II (D. N. Glover ed. 1985); “Oligonucleotide Synthesis” (M. J. Gait ed. 1984); “Nucleic Acid Hybridization” [B. D. Hames & S. J. Higgins eds. (1985)]; “Transcription and Translation” [B. D. Hames & S. J. Higgins eds. (1984)]; “Animal Cell Culture” [R. I. Freshney, ed. (1986)]; “Immobilized Cells And Enzymes” [IRL Press, (1986)]; B. Perb al, “A Practical Guide To Molecular Cloning” (1984). Therefore, if appearing herein, the following terms shall have the definitions set out below.
A “cDNA” is defined as copy-DNA or complementary-DNA, and is a product of a reverse transcription reaction from an mRNA transcript. “RT-PCR” refers to reverse transcription polymerase chain reaction and results in production of cDNAs that are complementary to the mRNA template(s).
The term “oligonucleotide” is defined as a molecule comprised of two or more deoxyribonucleotides, preferably more than three. Its exact size will depend upon many factors which, in turn, depend upon the ultimate function and use of the oligonucleotide. The term “primer” as used herein refers to an oligonucleotide, whether occurring naturally as in a purified restriction digest or produced synthetically, which is capable of acting as a point of initiation of synthesis when placed under conditions in which synthesis of a primer extension product, which is complementary to a nucleic acid strand, is induced, i.e., in the presence of nucleotides and an inducing agent such as a DNA polymerase and at a suitable temperature and pH. The primer may be either single-stranded or double-stranded and must be sufficiently long to prime the synthesis of the desired extension product in the presence of the inducing agent. The exact length of the primer will depend upon many factors, including temperature, source of primer and the method used. For example, for diagnostic applications, depending on the complexity of the target sequence, the oligonucleotide primer typically contains 15-25 or more nucleotides, although it may contain fewer nucleotides. The factors involved in determining the appropriate length of primer are readily known to one of ordinary skill in the art.
As used herein, random sequence primers refer to a composition of primers of random sequence, i.e. not directed towards a specific sequence. These sequences possess sufficient complementary to hybridize with a polynucleotide and the primer sequence need not reflect the exact sequence of the template.
“Restriction fragment length polymorphism” refers to variations in DNA sequence detected by variations in the length of DNA fragments generated by restriction endonuclease digestion.
A standard Northern blot assay can be used to ascertain the relative amounts of mRNA in a cell or tissue obtained from plant or other tissue, in accordance with conventional Northern hybridization techniques known to those persons of ordinary skill in the art. The Northern blot uses a hybridization probe, e.g. radiolabelled cDNA, either containing the full-length, single stranded DNA or a fragment of that DNA sequence at least 20 (preferably at least 30, more preferably at least 50, and most preferably at least 100 consecutive nucleotides in length). The DNA hybridization probe can be labelled by any of the many different methods known to those skilled in this art. The labels most commonly employed for these studies are radioactive elements, enzymes, chemicals which fluoresce when exposed to ultraviolet light, and others. A number of fluorescent materials are known and can be utilized as labels. These include, for example, fluorescein, rhodamine, auramine, Texas Red, AMCA blue and Lucifer Yellow. A particular detecting material is anti-rabbit antibody prepared in goats and conjugated with fluorescein through an isothiocyanate. Proteins can also be labeled with a radioactive element or with an enzyme. The radioactive label can be detected by any of the currently available counting procedures. The preferred isotope may be selected from 3H, 14C, 32P, 35S, 36Cl, 51Cr, 57Co, 58Co, 59Fe, 90Y, 125I, 131I, and 186Re. Enzyme labels are likewise useful, and can be detected by any of the presently utilized colorimetric, spectrophotometric, fluorospectrophotometric, amperometric or gasometric techniques. The enzyme is conjugated to the selected particle by reaction with bridging molecules such as carbodiimides, diisocyanates, glutaraldehyde and the like. Many enzymes which can be used in these procedures are known and can be utilized. The preferred are peroxidase, (-glucuronidase, (-D-glucosidase, (-D-galactosidase, urease, glucose oxidase plus peroxidase and alkaline phosphatase. U.S. Pat. Nos. 3,654,090, 3,850,752, and 4,016,043 are referred to by way of example for their disclosure of alternate labeling material and methods.
As used herein, “individual” refers to human subjects as well as non-human subjects. The examples herein are not meant to limit the methodology of the present invention to human subjects only, as the instant methodology is useful in the fields of veterinary medicine, animal sciences and such.
In one embodiment of the present invention, there is provided a method for detecting expression of a gene in blood from a subject, comprising the steps of: a) quantifying RNA from a subject blood sample; and b) detecting expression of the gene in the quantified RNA, wherein the expression of the gene in quantified RNA indicates the expression of the gene in the subject blood. An example of the quantifying method is by mass spectrometry.
In another embodiment of the present invention, there is provided a method for detecting expression of one or more genes in blood from a subject, comprising the steps of: a) obtaining a subject blood sample; b) extracting RNA from the blood sample; c) amplifying the RNA; d) generating expressed sequence tags (ESTs) from the amplified RNA product; and e) detecting expression of the genes in the ESTs, wherein the expression of the genes in the ESTs indicates the expression of the genes in the subject blood. Preferably, the subject is a fetus, an embryo, a child, an adult or a non-human animal. The genes are non-cancer-associated and tissue-specific genes. Still preferably, the amplification is performed by RT-PCR using random sequence primers or gene-specific primers.
In still another embodiment of the present invention, there is provided a method for detecting expression of one or more genes in blood from a subject, comprising the steps of: a) obtaining a subject blood sample; b) extracting DNA fragments from the blood sample; c) amplifying the DNA fragments; and d) detecting expression of the genes in the amplified DNA product, wherein the expression of the genes in the amplified DNA product indicates the expression of the genes in the subject blood.
In yet another embodiment of the present invention, there is provided a method for monitoring a course of a therapeutic treatment in an individual, comprising the steps of: a) obtaining a blood sample from the individual; b) extracting RNA from the blood sample; c) amplifying the RNA; d) generating expressed sequence tags (ESTs) from the amplified RNA product; e) detecting expression of genes in the ESTs, wherein the expression of the genes is associated with the effect of the therapeutic treatment; and f) repeating steps a)-e), wherein the course of the therapeutic treatment is monitored by detecting the change of expression of the genes in the ESTs. Such a method may also be used for monitoring the onset of overt symptoms of a disease, wherein the expression of the genes is associated with the onset of the symptoms. Preferably, the amplification is performed by RT-PCR, and the change of the expression of the genes in the ESTs is monitored by sequencing the ESTs and comparing the resulting sequences at various time points; or by performing single nucleotide polymorphism analysis and detecting the variation of a single nucleotide in the ESTs at various time points.
In still yet another embodiment of the present invention, there is provided a method for diagnosing a disease in a test subject, comprising the steps of: a) generating a cDNA library for the disease from a whole blood sample from a normal subject; b) generating expressed sequence tag (EST) profile from the normal subject cDNA library; c) generating a cDNA library for the disease from a whole blood sample from a test subject; d) generating EST profile from the test subject cDNA library; and e) comparing the test subject EST profile to the normal subject EST profile, wherein if the test subject EST profile differs from the normal subject EST profile, the test subject might be diagnosed with the disease.
In still yet another embodiment of the present invention, there is provided a kit for diagnosing, prognosing or predicting a disease, comprising: a) gene-specific primers; wherein the primers are designed in such a way that their sequences contain the opposing ends of two adjacent exons for the specific gene with the intron sequence excluded; and b) a carrier, wherein the carrier immobilizes the primer(s). Preferably, the gene-specific primers are selected from the group consisting of insulin-specific primers, atrial natriuretic factor-specific primers, zinc finger protein gene-specific primers, beta-myosin heavy chain gene-specific primers, amyloid precurser protein gene-specific primers, and adenomatous polyposis-coli protein gene-specific primers. Further preferably, the gene-specific primers are selected from the group consisting of SEQ ID Nos. 1 and 2; and SEQ ID Nos. 5 and 6. Such a kit may be applied to a test subject whole blood sample to diagnose, prognose or predict a disease by detecting the quantitative expression levels of specific genes associated with the disease in the test subject and then comparing to the levels of same genes expressed in a normal subject. Such a kit may also be used for monitoring a course of therapeutic treatment or monitoring the onset of overt symptoms of a disease.
In yet another embodiment of the present invention, there is provided a kit for diagnosing, prognosing or predicting a disease, comprising: a) probes derived from a whole blood sample for a specific disease; and b) a carrier, wherein the carrier immobilizes the probes. Such a kit may be applied to a test subject whole blood sample to diagnose, prognose or predict a disease by detecting the quantitative expression levels of specific genes associated with the disease in the test subject and then comparing to the levels of same genes expressed in a normal subject. Such a kit may also be used for monitoring a course of therapeutic treatment or monitoring the onset of overt symptoms of a disease.
Furthermore, the present invention provides a cDNA library specific for a disease, wherein the cDNA library is generated from whole blood samples.
The following examples are given for the purpose of illustrating various embodiments of the invention and are not meant to limit the present invention in any fashion.
Example 1
Construction of a cDNA Library
RNA extracted from human tissues (including fetal heart, adult heart, liver, brain, prostate gland and whole blood) were used to construct unidirectional cDNA libraries. The first mammalian heart cDNA library was constructed as early as 1982. Since then, the methodology has been revised and optimal conditions have been developed for construction of human heart and hematopoietic progenitor cDNA libraries (Liew et al., 1984; Liew 1993, Claudio et al., 1998). Most of the novel genes which were identified by sequence annotation can now be obtained as full length transcripts.
Example 2
Catalogue of Blood Cell ESTs
Random partial sequencing of expressed sequence tags (ESTs) of cDNA clones from the blood cell library was carried out to establish an EST database of blood. The known genes as derived from the ESTs were categorized into seven major cellular functions (Hwang, Dempsey et al., 1997).
Example 3
Differential Screening of cDNA Library
cDNA probes generated from transcripts of each tissue were used to hybridize the blood cell cDNA clones (Liew et al., 1997). The “positive” signals which were hybridized with P-labelled cDNA probes were defined as genes which shared identity with blood and respective tissues. The “negative” spots which were not exposed to P-labelled cDNA probes were considered to be blood-cell-enriched or low frequency transcripts.
Example 4
Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) Assay
RNA extracted from samples of human tissue was used for RT-PCR analysis (Jin et al. 1990). Three pairs of forward and reverse primers were designed for human cardiac beta-myosin heavy chain gene ((MyHC), amyloid precurser protein (APP) gene and adenomatous polyposis-coli protein (APC) gene. The PCR products were also subjected to automated DNA sequencing to verify the sequences as derived from the specific transcripts of blood.
Example 5
Detection of Tissue Specific Gene Expression in Human Blood Using RT-PCR
The beta-myosin heavy chain gene ((MyHC) transcript (mRNA) is known to be highly expressed in ventricles of the human heart. This sarcomeric protein is important for heart muscle contraction and its presence would not be expected in other non-muscle tissues and blood. In 1990, the gene for human cardiac (MyHC was completely sequenced (Liew et al. 1990) and was comprised of 41 exons and 42 introns.
The method of reverse transcription polymerase chain reaction (RT-PCR) was used to determine whether this cardiac specific mRNA is also present in human blood. A pair of primers was designed; the forward primer (SEQ ID No. 3) was on the boundary of exons 21 and 22, and the reverse primer (SEQ ID No. 4) was on the boundary of exons 24 and 25. This region of mRNA is only present in (MyHC and is not found in the alpha-myosin heavy chain gene ((MyHC).
A blood sample was first treated with lysing buffer and then undergone centrifuge. The resulting pellets were further processed with RT-PCR. RT-PCR was performed using the total blood cell RNA as a template. A nested PCR product was generated and used for sequencing. The sequencing results were subjected to BLAST and the identity of exons 21 to 25 was confirmed to be from (MyHC (FIG. 1A).
Using the same method just described, two other tissue specific genes—amyloid precursor protein (APP, forward primer, SEQ ID No. 7; reverse primer, SEQ ID No. 8) found in the brain and associated with Alzheimer's disease, and adenomatous polyposis coli protein (APC) found in the colon and rectum and associated with colorectal cancer (Groden et al. 1991; Santoro and Groden 1997)—were also detected in the RNA extracted from human blood (FIG. 1B).
Example 6
Multiple RT-PCR Analysis on a Drop of Blood from a Normal/Diseased Individual
A drop of blood was extracted to obtain RNA to carry out quantitative RT-PCR analysis. Specific primers for the insulin gene were designed: forward primer (5′-GCCCTCTGGGGACCTGAC-3′, SEQ ID No. 1) of exon 1 and reverse primer (5′-CCCACCTGCAGGTCCTCT-3′′, SEQ ID No. 2) of exons 1 and 2 of insulin gene. Such reverse primer was obtained by deleting the intron between the exons 1 and 2. Blood samples of 4 normal subjects were assayed. It was found that the insulin gene is expressed in the blood and the quantitative expression of the insulin gene in a drop of blood is influenced by fasting and non-fasting states of normal healthy subjects (FIG. 2). This very low level of expression of the insulin gene reflects the phenotypic status of a person and strongly suggests that there is a physiological and pathological role for its expression, contrary to the basal or illegitimate theory of transcription suggested by Chelly et al. (1989) and Kimoto (1998).
Same quantitative RT-PCR analysis was performed using insulin specific primers on RNA samples extracted from a drop of blood from a normal healthy person, a person having late-onset diabetes (Type II) and a person having asymptomatic diabetes. It was found that the insulin gene is expressed differentially amongst subjects that are healthy, diagnosed as type II diabetic, and also in an asymptomatic preclinical patient (FIG. 3).
Similarly, specific primers for the atrial natriuretic factor (ANF) gene were designed (forward primer, SEQ ID No. 5; reverse primer, SEQ ID No. 6) and RT-PCR analysis was performed on a drop of blood. ANF is known to be highly expressed in heart tissue biopsies and in the plasma of heart failure patients. However, atrial natriuretic factor was observed to be expressed in the blood and the expression of the atrial natriuretic factor gene is significantly higher in the blood of patients with heart failure as compared to the blood of a normal control patient.
Specific primers for the zinc finger protein gene (ZFP, forward primer, SEQ ID No. 9; reverse primer, SEQ ID No. 10) were also designed and RT-PCR analysis was performed on a drop of blood. ZFP is known to be high in heart tissue biopsies of cardiac hypertrophy and heart failure patients. In the present study, the expression of ZFP was observed in the blood as well as differential expression levels of ZFP amongst the normal, diabetic and asymptomatic preclinical subjects (FIG. 4); although neither of the non-normal subjects has been specifically diagnosed as suffering from cardiac hypertrophy and/or heart failure, the higher expression levels of the ZFP gene in their blood may indicate that these subjects are headed in that general direction.
It was hypothesized that a housekeeping gene such as glyceraldehyde dehydrogenase (GADH) which is required and highly expressed in all cells would not be differentially expressed in the blood of normal vs. disease subjects. This hypothesis was confirmed by RT-PCR using GADH specific primers (FIG. 4). Thus, GADH is useful as an internal control.
Standardized levels of insulin gene or ZFP gene expressed in a drop of blood were estimated using a housekeeping gene as an internal control relative to insulin or ZFP expressed (FIGS. 5A & 5B). The levels of insulin gene expressed in each fractionated cell from whole blood were also standardized and shown in FIG. 5C.
Example 7
Human Blood Cell cDNA Library
In order to further substantiate the present invention, differential screening of the human blood cell cDNA library was conducted. cDNA probes derived from human blood, adult heart or brain were respectively hybridized to the human blood cDNA library clones. As shown in FIG. 7, more than 95% of the “positively” identified clones are identical between the blood and other tissue samples.
DNA sequencing of randomly selected clones from the human whole blood cell cDNA library was also performed. This allowed information regarding the cellular function of blood to be obtained concurrently with gene identification. More than 20,000 expressed sequence tags (ESTs) have been generated and characterized to date, 17.6% of which did not result in a statistically significant match to entries in the GenBank databases and thus were designated as “Novel” ESTs. These results are summarized in FIG. 7 together with the seven cellular functions related to percent distribution of known genes in blood and in the fetal heart.
From 20,000 ESTs, 1,800 have been identified as known genes which may not all appear in the hemapoietic system. For example, the insulin gene and the atrial natriuretic factor gene have not been detected in these 20,000 ESTs but their transcripts were detected in a drop of blood, strongly suggesting that all transcripts of the human genome can be detected by performing RT-PCR analysis on a drop of blood.
In addition, approximately 400 novel genes have been identified from the 20,000 ESTs characterized to date, and these will be subjected to full length sequencing and open reading frame alignment to reduce the actual number of novel ESTs prior to screening for disease markers.
Analysis of the approximately 6,283 ESTs which have known matches in the GenBank databases revealed that this dataset represents over 1,800 unique genes. These genes have been catalogued into seven cellular functions. Comparisons of this set of unique genes with ESTs derived from human brain, heart, lung and kidney demonstrated a greater than 50% overlap in expression (Table 1).







TABLE 1







Overlap of Genes Expressed in Blood*











Tissues
ESTs**
Overlap in Blood















brain
134,000
60%



heart
65,000
59%



lung
60,200
58%



kidney
32,300
54%







*Estimated from limited known genes of about 1,800 as derived from the database of 6,297 ESTs from human blood cell library.



**Obtained from the National Centre of Biotechnology Information (NCBI), U.S.A.






Example 8
Blood Cell ESTs
The results from the differential screening clearly indicate that the transcripts expressed in the whole blood are reflective of genes expressed in all cells and tissues of the body. More than 95% of detectable spots were identical from two different tissues. The remaining 5% of spots may represent cell- or tissue-specific transcripts; however, results obtained from partial sequencing to generate ESTs of these clones revealed most of them not to be cell- or tissue-specific transcripts. Therefore, the negative spots are postulated to be reflective of low abundance transcripts in the tissue from which the cDNA probes were derived.
An alternative approach that was employed to identify transcripts expressed at low levels is the large-scale generation of expressed sequence tags (ESTs). There is substantial evidence regarding the efficiency of this technology to detect previously characterized (known) and uncharacterized (unknown or novel) genes expressed in the cardiovascular system (Hwang & Dempsey et al. 1997). In the present invention, 20,000 ESTs have been produced from a human blood cell cDNA library and resulted in the identification of approximately 1,800 unique known genes (Table 2)
In the most recent GenBank release, analysis of more than 300,000 ESTs in the database (dbESTs) generated more than 48,000 gene clusters which are thought to represent approximately 50% of the genes in the human genome. Only 4,800 of the dbESTs are blood-derived. In the present invention, 20,000 ESTs have been obtained to date from a human blood cDNA library, which provides the world's most informative database with respect to blood cell transcripts. From the limited amount of information generated so far (i.e. 1,800 unique genes), it has already been determined that more than 50% of the transcripts are found in other cells or tissues of the human body (Table 2). Thus, it is expected that by increasing the number of ESTs generated, more genes will be identified that have an overlap in expression between the blood and other tissues. Furthermore, the transcripts for several genes which are known to have tissue-restricted patterns of expression (i.e. (MyHC, APP, APC, ANF, ZFP) have also been demonstrated to be present in blood.
Most recently, a cDNA library of human hematopoietic progenitor stem cells has also been constructed. From the limited set of 1,000 ESTs, there are at least 200 known genes that are shared with other tissue related genes (Claudio et al. 1998).
Table 2 demonstrates the expression of known genes of specific tissues in blood cells. Previously, only the presence of “housekeeping” genes would have been expected. Additionally, the presence of at least 25 of the currently known 500 genes corresponding to molecular drug targets was detected. These molecular drug targets are used in the treatment of a variety of diseases which involve inflammation, renal and cardiovascular function, neoplastic disease, immunomodulation and viral infection (Drews & Ryser, 1997). It is expected that additional novel ESTs will represent future molecular drug targets.







TABLE 2







Comparison of 1,800 Unique Genes Identified in the Blood Cell cDNA Library to Genes


Previously Identified in Specific Tissues











No.





of
Accession
Tissue Distribution
















Gene Identification
ESTs
No.
Bl
Br
H
K
Li
Lu



















100 kDa coactivator
2
U22055

+



+



10 kD protein (BC10)
2
AF053470

+
+

+
+


14-3-3 epsilon
2
U54778

+
+


+


14-3-3 protein
11
U28964

+
+

+


15 kDa selenoprotein (SEP15)
1
AF051894

+
+


+


1-phosphatidylinositol-4-
1
S78798


phosphate 5-kinase isoform C


23 kD highly basic protein
21
X56932
+
+
+
+
+
+


2-5A-dependent RNase
1
L10381


2′-5′oligoadenylate synthetase
4
M87284
B


2 (OAS2)


26S proteasome subunit 11
1
AF086708


36 kDa phosphothyrosine
2
AJ223280
T

+


protein


3-7 gene product (non-exact
1
D64159


86% aa)


3-phosphoglycerate
1
AF006043
T
+
+


+


dehydrogenase (PGAD)


3-prime-phosphoadenosine 5-
2
U53447
+
+
+
+

+


prime-phosphosulfate


synthase 1 (PAPSS1)


46 kd mannose 6-phosphate
1
X56257


receptor (MPR46) (low


match)


5-aminoimidazole-4-
1
D89976


carboxamide ribonucleotide


transformylase


5′-nucleotidase
3
D38524
T
+


+


6-phosphofructo-2-
1
D49818

+


kinase/fructose-2,6-


biphosphatase 4 (PFKFB4)


6-phosphofructo-2-
1
AF041829


kinase/fructose-2,6-


bisphosphatase (PF2K)


71 kd heat shock cognate
23
Y00371


protein hsc70


76 kDa membrane protein
2
U81006

+
+
+
+
+


(P76)


8-oxoguanine DNA
1
U96710
B



+
+


glycosylase (OGG1)


a disintegrin and
1
AF009615
T



+


metalloprotease domain 10


(ADAM10)


a disintegrin and
1
D26579
B
+


metalloprotease domain 8


(ADAM8)


A kinase anchor protein 95
2
Y11997
B, T activated

+


+


(AKAP95)


A kinase anchor protein,
2
X97335

+
+
+

+


149 kD (AKAP149)


A4 differentiation-dependent
1
U93305


protein (A4), triple LIM


domain protein (LMO6), and


synaptophysin (SYP); calcium


channel alpha-1 subunit


(CACNA1F)


ABL and putative M8604 Met
1
U07561


protein


Absent in melanoma 1
1
U83115
+
+



+


(AIM1)


accessory proteins
2
Z31696

+
+


BAP31/BAP29 (DXS1357E)


acetyl-Coenzyme A
2
X12966
+
+
+
+
+
+


acyltransferase (peroxisomal


3-oxoacyl-Coenzyme A


thiolase) (ACAA)


acetyl-Coenzyme A
1
D88152
T lymphoma
+
+


transporter (ACATN)


acidic 82 kDa protein
4
U15552


acidic protein rich in leucines
1
Y07969
B
+
+

+
+


(SSP29)


Aconitase 2, mitochondrial
1
U80040
+
+
+
+

+


(ACO2)


actin binding protein
1
AF059569


MAYVEN


actin, beta (ACTB)
158
X04098
T, B
+
+

+


actin, beta (ACTB) (non-
1
M10277


exact, low match 73%)


actin, gamma (low score)
1
K00791


actin, gamma 1 (ACTG1)
4
X04098
+
+
+
+
+
+
high in many libraries


actin-binding LIM protein
4
D31883

+
+
+

+


(ABLIM)


Actinin, alpha 1 (ACTN1)
8
M95178

+
+
+

+


actinin, alpha 4 (ACTN4)
1
D89980

+
+

+


activated p21cdc42Hs kinase
1
L13738
B
+



+


(ACK)


activated RNA polymerase II
1
X79805
+
+
+
+

+


transcription cofactor 4 (PC4)


activating transcription factor
1
X55544


+


1 (ATF1)


activating transcription factor
1
X15875

+
+

+


2 (ATF2)


activating transcription factor
2
M86842




+
+


4 (tax-responsive enhancer


element B67) (ATF4)


active BCR-related gene
1
U01147
+
+
+
+

+


(ABR)


acyl-CoA oxidase (AOX)
1
U03254


acyl-Coenzyme A
2
M16827


dehydrogenase, C-4 to C-12


straight chain (ACADM)


acyl-Coenzyme A
3
D43682
+
+
+
+
+
+


dehydrogenase, very long


chain (ACADVL)


acyloxyacyl hydrolase
3
M62840
T

+

+
+


(neutrophil) (AOAH)


adaptin, delta (ADTD)
2
U91930

+
+

+


adaptin, delta (ADTD) (non-
1
AC005328


exact 59%)


adaptin, gamma (ADTG)
1
Y12226

+
+
+

+


adaptor complex sigma3B
2
X99459

+

+

+


(AP3S3)


adaptor protein p150
1
Y08991


adducin 1 (alpha) (ADD1)
2
L07261

+
+

+


adducin 1 (alpha) (add1)
3
L29296
+
+
+
+

+


adducin 3 (gamma) (ADD3)
3
U37122
B, W
+
+

+
+


adenine nucleotide
2
M57424

+
+

+


translocator 2 (fibroblast)


(ANT2)


adenine nucleotide
1
J02683


translocator 2 (fibroblast)


(ANT2) (non-exact 81%)


adenine nucleotide
1
J02683


translocator 2 (fibroblast)


(ANT2) (non-exact, 79%)


adenine nucleotide
1
J02683


translocator 2 (fibroblast)


(ANT2) (non-exact, 86%)


adenine nucleotide
3
J03592

+
+

+
+


translocator 3 (liver) (ANT3)


adenosine deaminase, RNA-
6
U18121

+
+

+


specific (ADAR)


adenylate cyclase 3 (ADCY3)
2
AF033861

+
+
+
+
+


adenylate cyclase 7 (ADCY7)
1
D25538


adenylate kinase 2 (AK2)
2
U39945

+
+

+
+


adenylate kinase 3 (AK3)
1
X60673


(non-exact, 67%)


adenylyl cyclase-associated
28
M98474
T

+

+


protein (CAP)


adipose differentiation-related
1
X97324


+

+
+


protein; adipophilin (ADFP)


ADP-ribosylation factor 1
13
M84326

+
+

+
+


(ARF1)


ADP-ribosylation factor 3
2
M33384

+
+

+


(ARF3)


ADP-ribosylation factor 4
1
M36341
T lymphoma
+
+


+


(ARF4)


ADP-ribosylation factor 5
1
M57567


+
+
+
+


(ARF5)


ADP-ribosylation factor
1
L04510

+


domain protein 1, 64 kD


(ARFD1)


ADP-ribosyltransferase
4
M32721
+
+
+
+
+
+


(NAD+; poly (ADP-ribose)


polymerase) (ADPRT)


adrenergic, beta, receptor
2
X61157
B
+


+


kinase 1 (ADRBK1)


adrenoleukodystrophy-like 1
1
AJ000327


(ALDL1)


AE-binding protein 1
1
D86479


(AEBP1) (non-exact, 62%)


AF-17
1
U07932


A-gamma-globin
1
V00514


A-gamma-globin
1
J00176


(chromosome 11 allele)


agammaglobulinaemia
1
U78027


tyrosine kinase (ATK)


AHNAK nucleoprotein
4
M80899
+
+
+
+

+


(desmoyokin) (AHNAK)


alanyl (membrane)
1
X13276


+

+


aminopeptidase


(aminopeptidase N,


aminopeptidase M,


microsomal aminopeptidase,


CD13, p150) (ANPEP)


alcohol dehydrogenase 5
1
M29872


(class III), chi polypeptide


(ADH5)


aldehyde dehydrogenase 1,
1
AF003341

+


+
+


soluble (ALDH1)


aldehyde dehydrogenase 10
2
U75286


(fatty aldehyde


dehydrogenase) (ALDH10)


aldehyde reductase 1 (low Km
3
J04795
B
+
+
+
+


aldose reductase) (ALDR1)


aldo-keto reductase family 1,
2
J04794
B
+
+

+


member A1 (aldehyde


reductase) (AKR1A1)


aldo-keto reductase family 1,
1
D17793

+
+
+

+


member C3 (3-alpha


hydroxysteroid


dehydrogenase, type II)


(AKR1C3)


aldo-keto reductase family 7,
1
Y16675

+
+

+
+


member A2 (aflatoxin


aldehyde reductase)


(AKR7A2)


aldolase A, fructose-
7
X12447

+
+

+


bisphosphate (ALDOA)


aldolase C, fructose-
2
X05196

+
+

+


bisphosphate (ALDOC)


alkaline phosphatase,
1
4502062


liver/bone/kidney (ALPL)


ALL-1 (=L04731; L04284
4
Z69780


HRX)


alpha mannosidase II isozyme
1
D55649

+


+


alpha thalassemia/mental
3
U75653
+
+
+
+

+


retardation syndrome X-


linked (ATRX)


alpha-2 macroglobulin
1
Z11711


alpha-2-globin
2
V00516


alpha-2-macroglobulin
1
U06985


receptor/lipoprotein receptor


protein (A2MR/LRP)


alpha-polypeptide of N-acetyl-
1
M13520


alpha-glucosaminidase


(HEXA)


alpha-spectrin
1
X86901


alpha-subunit of Gi2 a (GTP-
1
X07854


binding signal transduction


protein)


aminin receptor 1 (67 kD);
2
J03799
T
+
+

+
+


Ribosomal protein SA


(LAMR1)


aminolevulinate, delta-,
1
X64467

+


dehydratase (ALAD)


amino-terminal enhancer of
2
X73358
+
+
+
+

+


split (AES)


amino-terminal enhancer of
3
U04241
B
+
+

+
+


split (AES)


AMP deaminase isoform L
8
M91029

+



+


(AMPD2)


amphiphysin (Stiff-Mann
1
U07616
B
+



+


syndrome with breast cancer


128 kD autoantigen) (AMPH)


amphiphysin (Stiff-Mann
1
U07616


syndrome with breast cancer


128 kD autoantigen)


(AMPH)(non-exact, 68%)


amphiphysin (Stiff-Mann
1
U07616


syndrome with breast cancer


128 kD autoantigen)


(AMPH)(non-exact, 68%)


amphiphysin II
4
U87558

+
+

+


amphiphysin II (67% aa
1
AF068915


amphiphysin?)


amphiphysin II (non-exact
1
AF001383


69% aa)


amphiphysin-like (AMPHL)
1
U68485

+
+


amphiphysin-like (AMPHL)
1
AF068918


(low match)


AMY-1
1
D50692
B, T



+


amyloid beta (A4) precursor
1
L77864

+
+
+

+


protein-binding, family B,


member 1 (Fe65) (APBB1)


amyloid beta (A4) precursor-
6
L27631
T lymphoma
+
+

+
+


like protein 2 (APLP2)


ankyrin 3, node of Ranvier
1
U43965


(ankyrin G) (ANK) (non-


exact, 50%)


annexin I (lipocortin I)
1
X05908

+
+
+

+


(ANX1)


annexin II
1
D28364


annexin II (lipocortin II;
7
D00017
+
+
+
+
+
+
high in many libraries


calpactin I, heavy


polypeptide) (ANX2)


annexin IV (placental
1
M19383

+
+
+
+
+


anticoagulant protein II)


(ANX4)


annexin V (endonexin II)
2
M21731

+
+
+

+


(ANX5)


annexin V (endonexin II)
1
M19384

+
+
+

+


(ANXV)


annexin VI (p68) (ANX6)
6
Y00097

+
+
+

+


annexin VII (synexin)
1
J04543

+
+
+

+


(ANX7)


antigen identified by
2
M16279

+
+
+

+


monoclonal antibodies 12E7,


F21 and O13 (MIC2)


antigen identified by
3
J02939

+
+
+
+
+


monoclonal antibodies 4F2,


TRA1.10, TROP4, and T43


(MDU1)


antigen TQ1
1


anti-oxidant protein 2 (non-
1
D14662

+
+
+
+
+


selenium glutathione


peroxidase, acidic calcium-


independent phospholipase


A2) (KIAA0106)


APEX nuclease
5
X66133

+
+

+
+


(multifunctional DNA repair


enzyme) (APEX)


Apolipoprotein L (APOL)
1
Z82215


(59% aa)


apoptosis inhibitor 1 (API1)
1
L49431

+
+
+
+
+


apoptosis inhibitor 4
1
U75285
B, W
+
+

+


(survivin) (API4)


apoptosis inhibitor 5 (API5)
1
U83857
T lymphoma
+


+


apoptosis specific protein
1
Y11588
B
+


+
+


(ASP)


apoptotic protease activating
1
AF013263
B
+
+

+


factor (APAF1)


aquaporin 3 (AQP3)
1
AB001325
T



+


aquaporin 9 (AQP9)
7
AB008775
T activated



+


arachidonate 12-lipoxygenase
1
M58704
T



+
+


(ALOX12)


arachidonate 5-lipoxygenase-
3
X52195
+
+

+

+


activating protein


(ALOX5AP)


ariadne homolog (ARI)
1
AJ009771
+
+
+
+

+


ariadne-2 (D. melanogaster)
1
AF099149
+
+
+
+

+


homolog (all-trans retinoic


acid inducible RING finger)


(ARI2)


ARP1 (actin-related protein 1,
1
X82206

+


+


yeast) homolog A (centractin


alpha) (ACTR1A)


ARP2 (actin-related protein 2,
9
AF006082

+
+

+
+


yeast) homolog (ACTR2)


ARP2/3 protein compex
5
AF006085
T activated, W
+
+

+


subunit 34 (ARC34)


Arp2/3 protein compex
6
AF006084
monocyte
+
+

+


subunit p41 (ARC41)


stimulated


Arp2/3 protein compex
1
AF006084


subunit p41 (ARC41)) (low


match)


Arp2/3 protein complex
20
AF017807

+
+

+
+


subunit p16 (ARC16)


Arp2/3 protein complex
2
AF006087

+
+

+
+


subunit p20 (ARC20)


Arp2/3 protein complex
3
AF006086
W



+
+


subunit p21(ARC21)


ARP3 (actin-related protein 3,
11
AF006083
W

+

+
+


yeast) homolog (ACTR3)


arrestin, beta 2 (ARRB2)
1
AF106941
B, T, W
+
+

+


arsA (bacterial) arsenite
1
AF047469
B, T
+


+


transporter, ATP-binding,


homolog 1 (ASNA1)


aryl hydrocarbon receptor
2
AF044288
B
+
+

+


nuclear translocator-like


(ARNTL)


aryl hydrocarbon receptor-
1
U31913
+
+
+
+

+


interacting protein (AIP)


arylsulfatase A (ARSA)
1
X52151
T activated
+


+


asialoglycoprotein receptor 2
1
M11025




+
+


(ASGR2)


asparaginyl-tRNA synthetase
3
D84273

+
+

+


(NARS)


aspartyl-tRNA synthetase
1
J05032
B
+
+

+


(DARS)


ataxia telangiectasia mutated
1
U82828
B, T

+

+


(includes complementation


groups A, C and D) (ATM)


ataxin-2-like protein A2LP
1
AF034373
B, T activated
+
+


+


(A2LG)


ATF6
1
AF005887

+


+


ATP binding cassette
1
U88667


transporter (ABCR) (non-


exact 80%)


ATP synthase (F1-ATPase)
1
X59066


alpha subunit, mitochondrial


ATP synthase beta subunit
1
M19482


gene


ATP synthase, H+
1
X60221
+
+
+
+

+


transporting, mitochondrial F0


complex, subunit b, isoform 1


(ATP5F1)


ATP synthase, H+
1
X69907
T activated
+
+

+
+


transporting, mitochondrial F0


complex, subunit c (subunit


9), isoform 1 (ATP5G1)


ATP synthase, H+
3
D14710


transporting, mitochondrial F1


complex, alpha subunit,


isoform 1, cardiac muscle


(ATP5A1)


ATP synthase, H+
1
D14710


transporting, mitochondrial F1


complex, alpha subunit,


isoform 1, cardiac muscle


(ATP5A1) (low match)


ATP synthase, H+
2
M27132


transporting, mitochondrial F1


complex, beta polypeptide


(ATP5B)


ATP synthase, H+
1
D16563
W
+
+
+
+


transporting, mitochondrial F1


complex, gamma polypeptide


1 (ATP5C1)


ATP synthase, H+
1
AF092124
+
+
+
+
+
+


transporting, mitochondrial


F1F0, subunit g (ATP5JG)


ATP/GTP-binding protein
2
U73524
+
+
+
+

+


(HEAB)


ATPase, Ca++ transporting,
5
Z69881

+


ubiquitous (ATP2A3)


ATPase, H+ transporting,
2
D89052
+
+
+
+

+


lysosomal (vacuolar proton


pump) 21 kD (ATP6F)


ATPase, H+ transporting,
1
X76228

+
+
+

+


lysosomal (vacuolar proton


pump) 31 kD (ATP6E)


ATPase, H+ transporting,
5
X69151

+
+
+

+


lysosomal (vacuolar proton


pump) 42 kD; Vacuolar


proton-ATPase,


subunit C; V-ATPase, subunit


C (ATP6D)


ATPase, H+ transporting,
3
L09235

+

+


lysosomal (vacuolar proton


pump), alpha polypeptide,


70 kD, isoform 1 (ATP6A1)


ATPase, H+ transporting,
6
X62949
+
+
+
+

+


lysosomal (vacuolar proton


pump), beta polypeptide,


56/58 kD, isoform 2


(ATP6B2)


ATPase, H+ transporting,
2
AF038954
+
+
+
+

+
high in testis


lysosomal (vacuolar proton


pump), member J (ATP6J)


ATPase, H+ transporting,
1
D16469

+
+
+

+


lysosomal (vacuolar proton


pump), subunit 1 (ATP6S1)


ATP-binding cassette 50
1
AF027302
+
+
+
+

+


(TNF-alpha stimulated)


(ABC50)


ATP-binding cassette protein
1
AF047690


M-ABC1 (mitochondrial)


ATP-dependent RNA helicase
1
AJ010840
T lymphoma

+

+


autoantigen (Hs.75528)
2
L05425
T activated

+


autoantigen (Hs.75528) (non-
1
L05425


exact 84%)


autoantigen (Hs.75682)
1
U17474
B
+



+


autoantigen La/SS-B
1
Z35127


axin (AXIN1)
1
AF009674
T
+


axonemal dynein heavy chain
1
AJ000522





+


(DNAH17)


BAI1-associated protein 3
1
AB017111


(BAIAP3) (non-exact 54%)


basement membrane-induced
1
AF044896


gene (ICB1)


basic leucine zipper nuclear
2
U79751


factor 1 (JEM-1) (BLZF1)


basic transcription factor 3
5
X74070
+
+
+
+
+
+


(BTF3)


basigin (BSG)
1
L10240

+


+


BC-2
1
AF042384
B

+
+
+


B-cell CLL/lymphoma 6 (zinc
1
U00115

+
+


finger protein 51) (BCL6)


B-cell translocation gene 1,
1
X61123


+


+


anti-proliferative (BTG)


BCL2/adenovirus E1B 19 kD-
1
U15173
B
+


+
+


interacting protein 2 (BNIP2)


BCL2/adenovirus E1B 19 kD-
2
AF067396

+
+
+

+


interacting protein 3-like


(BNIP3L)


beclin 1 (coiled-coil, myosin-
1
AF077301
B
+
+

+


like BCL2-interacting protein)


(BECN1)


beta-1,2-N-
2
U15128


acetylglucosaminyltransferase


II (MGAT2)


beta-2-microglobulin (B2M)
63
S82297
+
+
+
+
+
+
high in invasive











prostate tumor


beta-hexosaminidase alpha
1
M16411


chain (HEXA)


beta-tubulin
7
V00599
+
+
+
+
+
+
high in many libraries


beta-tubulin (non-exact, 76%)
1
AF070561


beta-tubulin, pseudogene
1
J00315


BING4
1
Z97184


biotinidase (BTD) (non-eact
1
U03274


62%)


biotinidase (BTD) (non-exact
1
U03274


70%)


biotinidase (BTD) (non-exact,
1
U03274


56%)


BIOTINIDASE
1
P43251


PRECURSOR


biphenyl hydrolase-like
1
X81372

+


+


(serine hydrolase) (BPHL)


bone marrow stromal cell
1
D21878




+


antigen 1 (BST1)


box-dependent myc-
1
AF043900


interacting protein isoform


BIN1-10 (BIN1)


box-dependent myc-
1
AF043900


interacting protein isoform


BIN1-10 (BIN1) (non-exact,


64%)


brain my047 protein
1
AF063605
T
+
+

+


branched chain keto acid
3
Z14093
T
+
+

+


dehydrogenase E1, alpha


polypeptide (maple syrup


urine disease) (BCKDHA)


BRCA1 associated protein-1
1
D87462
+
+
+
+


(ubiquitin carboxy-terminal


hydrolase) (BAP1)


BRCA1, Rho7 and vatI genes,
1
L78833


and ipf35


breakpoint cluster region
2
AF044773

+
+


protein, uterine leiomyoma, 1;


barrier to autointegration


factor (BCRP1)


breakpoint cluster region
2
AF044774

+
+

+
+


protein, uterine leiomyoma, 2


(BCRP2)


breast cancer anti-estrogen
1
U92715


resistance 3 (BCAR3) (non-


exact 73%)


bromodomain-containing
2
M91585

+


protein, 140 kD (peregrin)


(BR140)


Bruton's agammaglobulinemia
1
U13424


tyrosine kinase (Btk)


Bruton's tyrosine kinase
1
U78027


(BTK)


Bruton's tyrosine kinase
1
U78027


(BTK), alpha-D-galactosidase


A (GLA), L44-like ribosomal


protein (L44L) and FTP3


(FTP3)


BS4
1
AF108083


BTG2 (BTG2)
6
Y09943
+
+
+
+

+


BTK region clone ftp
1
U78027
+
+
+
+

+


BTK region clone ftp-3
1
U01923

+
+

+


BUB3 (budding uninhibited
4
AF053304
+
+
+
+

+


by benzimidazoles 3, yeast)


homolog (BUB3)


butyrate response factor 1
4
X79067
+
+
+
+

+


(EGF-response factor 1)


(BRF1)


butyrophilin (BTF1)
7
U90543

+
+

+


butyrophilin like receptor
1
AB020625.1


CAG repeat containing
2
U80744

+
+


(CTG4A)


CAGH32
2
U80743

+
+

+


calcium channel, voltage-
1
M83566


dependent, L type, alpha 1D


subunit (CACNA1D) (low


match)


calcium/calmodulin-
1
AF069765

+
+
+

+


dependent protein kinase


(CaM kinase) II gamma


(CAMK2G)


calcium/calmodulin-
1
AF101264
B
+
+

+


dependent protein kinase


kinase (KIAA0787)


calmodulin (=M19311)
7
D45887


calmodulin 1 (phosphorylase
6
M27319
B
+
+

+
+


kinase, delta) (CALM1)


calnexin (CANX)
3
M94859
T
+


+
+


calpain, large polypeptide L1
5
X04366

+
+

+
+


(CAPN1)


calpain, large polypeptide L2
5
M23254

+
+


(CANP2)


calpain, small polypeptide
1
X04106

+
+

+
+


(CAPN4)


calpastatin (CAST)
3
D16217




+


Calponin 2
2
D83735

+

+

+


calponin 2 (CNN2)
1
D83735
B, T
+


+


calponin 2 (CNN2) (low
1
D83735


score)


calumenin (CALU)
3
AF013759
B

+

+
+


cAMP response element-
4
L05912


binding protein CRE-Bpa


(H_GS165L15.1)


cAMP-dependent protein
1
M90360


kinase type II (Ht31)


canicular multispecific
1
AF009670



+
+
+


organic anion transporter


(CMOAT2)


capping protein (actin
6
U56637
B, T

+


+


filament) muscle Z-line, alpha


1 (CAPZA1)


capping protein (actin
2
U03269
B
+
+


filament) muscle Z-line, alpha


2 (CAPZA2)


capping protein (actin
1
U03271
+
+
+
+

+


filament) muscle Z-line, beta


(CAPZB)


capping protein (actin
8
M94345
+
+

+

+


filament), gelsolin-like


(CAPG)


carbamoyl-phosphate
1
D78586
+
+
+
+

+


synthetase 2, aspartate


transcarbamylase, and


dihydroorotase (CAD)


carbonic anhydrase V,
1
L19297

+


+


mitochondrial (CA5)


carboxypeptidase D (CPD)
3
U65090
B
+
+


carnitine/acylcarnitine
1
Y10319

+
+

+


translocase (CACT)


Cas-Br-M (murine) ecotropic
2
X57110




+


retroviral transforming


sequence (cbl)


casein kinase 1, alpha 1
1
L37042
+
+
+
+

+


(CSNK1A1)


casein kinase 2, alpha 1
2
M55265
B
+


+
+


polypeptide (CSNK2A1)


casein kinase I gamma 3L
1
AF049090.1


(CSNK1G3L)


casein kinase II alpha
1
X69951


subunit(=S72393)


CASP8 and FADD-like
4
AF015450

+
+
+
+
+


apoptosis regulator (CFLAR)


caspase 1, apoptosis-related
7
U13697
+


+


cysteine protease (interleukin


1, beta, convertase) (CASP1)


caspase 10, apoptosis-related
1
U60519
B, T



+


cysteine proteas (CASP10)


activated, T





lymphoma


caspase 3, apoptosis-related
3
U13737
B, T
+
+
+
+


cysteine protease (CASP3)


caspase 4, apoptosis-related
6
U25804
+
+
+
+

+


cysteine protease (CASP4)


caspase 5, apoptosis-related
1
U28015


+


cysteine protease (CASP5)


caspase 8, apoptosis-related
2
X98173

+

+

+


cysteine protease (CASP8)


caspase 9, apoptosis-related
1
U56390
B


+
+


cysteine protease (CASP9)


catalase (CAT)
5
X04076
B
+
+

+


catechol-O-methyltransferase
1
M65213

+
+

+


(COMT)


catenin (cadherin-associated
6
D14705

+
+


protein), alpha 1 (102 kD)


(CTNNA1)


cathelicidin antimicrobial
1
X89658
B


peptide (CAMP)


cathepsin B (CTSB)
4
L16510


+

+
+


cathepsin C (CTSC)
3
U79415

+
+
+

+


cathepsin D (lysosomal
4
M11233

+
+

+


aspartyl protease) (CTSD)


cathepsin E (CTSE)
1
J05036




+


cathepsin G (CTSG)
1
M16117
T, W

+


cathepsin S (CTSS)
34
M86553
B, Monocyte



+
+





stimulated, T





lymphoma


cathepsin W (lymphopain)
4
AF013611





+


(CTSW)


CBF1 interacting corepressor
1
AF098297


CIR (=U03644 recepin)


CCAAT/enhancer binding
3
X87248

+
+
+

+


protein (C/EBP), alpha


(CEBPA)


CCAAT/enhancer binding
1
S63168


+

+
+


protein (C/EBP), delta


(CEBPB)


CCAAT-box-binding
2
M37197
T lymphoma


+
+


transcription factor (CBF2)


CCR5 receptor (CCR5) (non-
1
AF011504


exact?)


CD14 antigen (CD14)
11
M86511
+
+
+
+

+


CD18 (=M95293)
4
X64071


CD1C antigen, c polypeptide
2
M28827





+


(CD1C)


CD2 antigen (cytoplasmic
1
AF104222


tail)-binding protein 2


(CD2BP2)


CD2 antigen (p50), sheep red
4
M14362
+

+
+

+


blood cell receptor (CD2)


CD2 cytoplasmic tail-binding
2
AF038602




+


protein 1 (CD2BP1)


CD20 antigen (CD20)
1
X12530


CD20 receptor (S7)
1
X07203


CD22 antigen (CD22)
1
U62631
B


CD24 signal transducer
1
M58664


CD33 antigen (gp67) (CD33)
1
M23197




+


CD33 antigen-like 2; OB
1
U71383


binding protein-2 (CD33L2)


(non-exact, 68%)


CD33L2 (61% aa)
1
D86359


CD36 antigen (collagen type I
7
M98398
T lymphoma

+

+
+


receptor, thrombospondin


receptor) (CD36)


CD37 antigen (CD37)
5
X14046
+
+

+

+


CD38 alt
1
D84277


CD39 antigen (CD39)
1
U87967
B
+


+
+


CD3D antigen, delta
1
X03934


+
+

+


polypeptide (TiT3 complex)


(CD3D)


CD3E antigen, epsilon
1
X03884
+


+


polypeptide (TiT3 complex)


(CD3E)


CD3G antigen, gamma
2
X06026
W



+


polypeptide (TiT3 complex)


(CD3G)


CD3Z antigen, zeta
2
J04132
+


+


polypeptide (TiT3 complex)


(CD3Z)


CD3-zeta (clone pBS NK1)
1
X55510


CD4 (low match)
1
S68043


CD4 antigen (p55) (CD4)
4
M12807

+
+

+


CD44 antigen (homing
6
X56794
W



+
+


function and Indian blood


group system (CD44)


CD48 antigen (B-cell
3
X06341
+
+
+
+

+


membrane protein) (CD48)


CD53 antigen (CD53)
10
L11670
+
+

+

+


CD53 antigen (CD53) (low
1
M60871


match)


CD63 antigen (melanoma 1
3
M59907


antigen) (CD63)


CD68 antigen (CD68)
2
S57235

+
+

+
+


CD74 antigen (invariant
72
K01144
+
+
+
+
+
+
high in many libraries


polypeptide of major


histocompatibility complex,


class II antigen-associated)


(CD74)


CD79A antigen
2
M80462


+


(immunoglobulin-associated


alpha) (CD79A)


CD79B antigen
2
M89957
+


(immunoglobulin-associated


beta) (CD79B)


CD8 antigen, alpha
2
M27161
+


+

+


polypeptide (p32) (CD8A)


CD8 antigen, beta polypeptide
1
X13445
W


1 (p37) (CD8B1)


CD81 antigen (target of
1
M33680

+
+


+


antiproliferative antibody 1


(CD81)


CD83 antigen (activated B
1
Q01151
B
+
+


+


lymphocytes, mmunoglobulin


superfamily) (CD83)


CD84 antigen (leukocyte
1
U82988

+
+


+


antigen) (CD84)


CD86 antigen
1
L25259

+


CD9 antigen (p24) (CD9)
2
M38690


+

+
+


CD97 antigen (CD97)
12
X84700
+
+

+


CD97 antigen (CD97) (noin-
1
P48960


exact 59%)


CD97 antigen (CD97) (non-
1
X94630
+
+

+


exact 62%)


CDC23 (cell division cycle
1
AF053977

+


+
+


23, yeast, homolog) (CDC23)


CDC37 homolog
1
U63131
B
+
+

+
+


Cdc42 effector protein 3
2
AF104857
B
+
+

+


(CEP3)


CDC-like kinase (CLK)
1
L29219

+
+
+

+


CDC-like kinase 2 (CLK2)
1
AF023268
B
+
+


CDW52 antigen (CAMPATH-
13
X15183
T activated
+
+

+


1 antigen) (CDW52)


cell cycle progression
1
AF011794


restoration 8 protein(CPR8)


cell division cycle 10
4
S72008
+
+
+
+

+


(homologous to CDC10


of S. cerevisiae)


(CDC10)


cell division cycle 20,
1
U05340

+
+
+


S. cerevisiae homolog


(CDC20)


cell division cycle 25B
6
Z68092
+
+
+
+

+


(CDC25B)


cell division cycle 2-like 1
1
AF067514


(PITSLRE proteins)


(CDC2L1) (non-exact 42%)


cell division cycle 42 (GTP-
5
M35543
+
+
+
+

+


binding protein, 25 kD)


(CDC42)


cell division protein (non-
1
AF063015


exact 68%)


CELL-CYCLE NUCLEAR
1
Q13033


AUTOANTIGEN SG2NA


(S/G2 NUCLEAR ANTIGEN)


centromere protein B (80 kD)
1
X55039

+


+


(CENPB)


cep250 centrosome associated
3
AF022655
B
+


+


protein


ceroid-lipofuscinosis,
7
AF017456
+
+
+
+
+
+
high in bone


neuronal 2, late infantile


(Jansky-Bielschowsky


disease) (CLN2)


c-fgr (=M63877 nonreceptor
6
X52206


protein-tyrosine kinase (fgr))


CGI-19 protein
3
AF132953.1


chaperonin containing TCP1,
1
X74801

+
+


+


subunit 3 (gamma) (CCT3)


chaperonin containing TCP1,
1
AF026291

+
+

+
+


subunit 4 (delta) (CCT4)


chaperonin containing TCP1,
4
L27706
B
+
+


subunit 6A (zeta 1) (CCT6A)


chaperonin containing TCP1,
4
AF026292
B
+



+


subunit 7 (eta) (CCT7)


Chediak-Higashi syndrome 1
1
U67615
B, T
+
+

+


(CHS1)


lymphoma


Chediak-Higashi syndrome 1
1
U67615


(CHS1) (low score)


chemokine (C-C motif)
4
U03905


receptor 2 (CCR2)


chemokine (C-C motif)
1
X85740


receptor 4 (CCR4) (low


match) (may contain repeat)


chemokine (C-C motif)
6
L31581


receptor 7 (CCR7)


chemokine (C—X3—C) receptor
5
U20350

+


1 (CX3CR1)


chemokine (C—X—C motif),
5
M99293
+
+
+
+

+


receptor 4 (fusin) (CXCR4)


chitinase 3-like 1 (cartilage
2
M80927

+

+

+


glycoprotein-39) (CHI3L1)


chitinase 3-like 2 (CHI3L2)
2
U49835

+

+

+


chloride channel 1, skeletal
1
G18280


muscle (CLCN1)


chloride channel 6 (CLCN6)
1
D28475

+
+


Chloride intracellular channel
1
U93205
+
+
+
+

+


1 (CLIC1)


chondroitin sulfate
5
X15998


+


proteoglycan 2 (versican)


(CSPG2)


chondroitin sulfate
2
J02814


+


+


proteoglycan core protein


chromatin assembly factor 1
1
Q09028


p48 subunit (CAF-1 P48


subunit) (retinoblastoma


binding protein p48)


(retinoblastoma-binding


protein 4) (MSI1 protein


homolog)


chromodomain helicase DNA
2
AF006513


binding protein 1 (CHD1)


chromodomain helicase DNA
1
AF054177


binding protein 1-like


(CHD1L)


chromodomain helicase DNA
1
AF006514
B
+
+

+


binding protein 2 (CHD2)


chromodomain helicase DNA
1
AF006515


binding protein 3 (CHD3)


chromodomain helicase DNA
5
X86691
+
+
+
+

+


binding protein 4 (CHD4)


chromosome 1 open reading
1
AF054176


frame 7 (C1ORF7)


chromosome 1 specific
1
AB007962


transcript KIAA0493


chromosome 17 open reading
1
AJ008112
T
+


frame 1B (C17ORF1B)


chromosome 4 open reading
1
AF006621

+
+
+

+


frame 1 (C4ORF1)


chromosome condensation 1-
2
AF060219

+
+
+

+


like (CHC1L)


chromosome X open reading
1
Y15164
B
+
+

+


frame 5 (CXORF5)


chromosome-associated
2
AF092564
B
+
+

+
+


polypeptide C(CAP-C)


cig42
1
AF026944


cig5
3
AF026941


citrate synthase (CS)
2
AF047042
B
+
+

+
+


class I major
2
U31372


histocompatibility antigen


(HLA-Cw3)


class I major
1
U31372


histocompatibility antigen


(HLA-Cw3) (low match)


clathrin assembly protein
3
U45976
B
+
+


+


lymphoid myeloid leukemia


(CALM)


clathrin heavy chain
1
X55878


clathrin, heavy polypeptide-
1
D21260


like 2 (CLTCL2)


clathrin, light polypeptide
1
M20472


(Lca) (CLTA) (low match)


clathrin-
3
D63475

+
+
+
+
+


associated/assembly/adaptor


protein, medium 1 (CLAPM1)


cleavage stimulation factor, 3′
1
M85085


pre-RNA, subunit 2 64 kD


(CSTF2) (non-exact 82%)


cleavage stimulation factor, 3′
1
U15782
B
+
+

+


pre-RNA, subunit 3, 77 kD


(CSTF3)


clk3
1
L29220
B
+
+


clone 23815 (Hs.82845)
1
U90916

+
+


+


clone 24592 mRNA sequence
1
D88378
+
+
+
+

+


Clq/MBL/SPA receptor
1
U94333


ClqR(p) ( )


clusterin (complement lysis
1
M64722
+
+
+
+
+
+


inhibitor, SP-40,40, sulfated


glycoprotein 2, testosterone-


repressed


prostate message 2,


apolipoprotein J) (CLU)


CMP-sialic acid transporter
1
D87969
B
+
+


(CMPST)


CMRF35
3
X66171


c-myc oncogene containing
1
X54629


coxIII


coagulation factor II
1
M62424

+
+


+


(thrombin) receptor (F2R)


coagulation factor V
1
M14335

+

+
+


(proaccelerin, labile factor)


(F5)


coagulation factor XIII a
3
M21998


subunit


coagulation factor XIII, A1
6
M14354

+
+
+

+


polypeptide (F13A1)


coated vesicle membrane
1
X92098
+
+
+
+
+
+


protein (RNP24)


coatomer protein complex,
5
U24105
T
+


+


subunit alpha (COPA)


Cofilin 1 (non-muscle)
13
X95404
+
+
+
+
+
+
high in fetal brain


(CFL1)


cold inducible RNA-binding
7
D78134

+
+


+


protein (CIRBP)


cold shock domain protein A
3
X95325

+
+


(CSDA)


collagen, type IX, alpha 2
3
AF019406
B


(COL9A2)


colony stimulating factor 1
3
X03663

+


+
+


receptor, formerly


McDonough feline sarcoma


viral (v-fms) oncogene


homolog (CSF1R)


colony stimulating factor 2
5
M59941


receptor, beta, low-affinity


(granulocyte-macrophage)


(CSF2RB)


colony stimulating factor 2
1
M59941


receptor, beta, low-affinity


(granulocyte-macrophage)


(CSF2RB) (low match)


colony stimulating factor 3
16
X55720

+


receptor (granulocyte)


(CSF3R)


complement component 5
1
M62505
L


receptor 1 (C5a ligand)


(C5R1)


conserved gene amplified in
2
AF000152

+
+
+

+


osteosarcoma (OS4)


COP9 (constitutive
2
AF031647

+
+


+


photomorphogenic,


Arabidopsis, homolog)


subunit 3 (COPS3)


COP9 homolog (HCOP9)
2
U51205
B
+
+
+
+
+


COPII protein, homolog of s. cerevisiae
4
X97064

+
+


SEC23p (SEC23A)


copine I (CPNE1)
2
U83246
B
+
+

+


copine I (CPNE1) (low score)
1
U83246


coproporphyrinogen oxidase
1
D16611


+

+
+


(coproporphyria,


harderoporphyria) (CPO)


core-binding factor, beta
1
L20298

+


subunit (CBFB)


coronin
22
X89109
T, W
+
+

+


coronin (low match)
1
U34690


coronin (non-exact, 71%)
1
X89109


cot (cancer Osaka thyroid)
1
D14497
+
+
+
+

+


oncogene (COT)


cryptochrome 1 (photolyase-
1
D84657

+
+


+


like) (CRY1)


CTD (carboxy-terminal
1
AF081287

+
+
+

+


domain, RNA polymerase II,


polypeptide A) phosphatase,


subunit 1 (CTDP1)


C-terminal binding protein 1
1
U37408
B
+
+

+


(CTBP1)


C-terminal binding protein 2
2
AF016507

+
+

+


(CTBP2)


CUG triplet repeat, RNA-
3
U63289

+
+
+

+


binding protein 1 (CUGBP1)


cullin 1 (CUL1)
3
U58087

+
+
+

+


cullin 3 (CUL3)
2
U58089

+
+
+

+


cut (Drosophila)-like 1
1
M74099
B
+


(CCAAT displacement


protein) (CUTL1)


cyclin D2 (CCND2)
2
D13639

+
+
+

+


cyclin D3 (CCND3)
5
M92287
B, T

+

+





lymphoma


cyclin G1 (CNNG1)
1
D78341
B
+
+


+


cyclin I
3
D50310
B
+


+


cyclin T2 (CNNT2)
1
AF048732
B, T
B





lymphoma


cyclin-dependent kinase 2
1
X62071


(CDK2)


cyclin-dependent kinase
1
S76986


inhibitor (p27Kip1)


cyclin-dependent kinase
2
S67388
+
+
+
+
+
+


inhibitor 1A (p21, Cip1)


(CDKN1A)


CYP2D7-CYP2D6 intergenic
1
X90926


region (partial)


cystatin B (stefin B) (CSTB)
1
L03558


+

+
+


cysteine and glycine-rich
5
L54057


+


protein 3 (cardiac LIM


protein) (CSRP3)


cytidine deaminase (CDA)
2
L27943




+


cytochrome b
1
AF042500


cytochrome b (CYTB) (isolate
1
AF042518


Aus5)


cytochrome b(-245) beta chain
2
X05895


N-terminal region (X-linked


granulomatous disease gene)


cytochrome b-245, beta
2
X04011
+


+

+


polypeptide (chronic


granulomatous disease)


(CYBB)


cytochrome C
1
P00001


cytochrome c oxidase subunit
1
U90915
T
+
+

+
+


IV (COX4)


cytochrome c oxidase subunit
2
M59250




+


Vb (COX5B)


cytochrome c oxidase subunit
6
AB007618
+
+
+
+

+


VII-related protein


(COX7RP)


cytokine suppressive anti-
1
L35263
lymphocyte
+
+

+


inflammatory drug binding


protein 1 (p38 MAP kinase)


(CSBP1)


Cytoplasmic
1
S69272


+


antiproteinase = 38 kda


intracellular serine proteinase


inhibitor


cytotoxic granule-associated
1
S70114


RNA-binding protein p40-


TIA-1


D123 (D123)
1
D14878
+
+

+

+


D2-2
1
AF019226


D38
1
X74802


damage-specific DNA binding
2
AJ002955
+
+
+
+
+
+


protein 1 (127 kD) (DDB1)


DCHT (low match)
1
AF017635


DEAD/H (Asp-Glu-Ala-
1
U78524

+
+
+
+
+


Asp/His) box binding protein


1 (DDXBP1)


DEAD/H (Asp-Glu-Ala-
2
U59321
T
+
+

+
+


Asp/His) box polypeptide


(72 KD) (P72)


DEAD/H (Asp-Glu-Ala-
1
X70649

+
+


+


Asp/His) box polypeptide 1


(DDX1)


DEAD/H (Asp-Glu-Ala-
2
AB001636


Asp/His) box polypeptide 15


(DDX15)


DEAD/H (Asp-Glu-Ala-
2
AB011149
+
+
+
+

+


Asp/His) box polypeptide 16


(DDX16)


DEAD/H (Asp-Glu-Ala-
3
U50553
+
+
+
+

+


Asp/His) box polypeptide 3


(DDX3)


DEAD/H (Asp-Glu-Ala-
37
X15729
+
+
+
+

+


Asp/His) box polypeptide 5


(RNA helicase, 68 kD)


(DDX5)


DEAD/H (Asp-Glu-Ala-
1
AF015812


Asp/His) box polypeptide 5


(RNA helicase, 68 kD)


(DDX5) (low match)


DEAD/H (Asp-Glu-Ala-
2
D17532
+
+


Asp/His) box polypeptide 6


(RNA helicase, 54 kD)


(DDX6)


DEAD/H (Asp-Glu-Ala-
1
D50487

+
+
+

+


Asp/His) box polypeptide 8


(RNA helicase, 54 kD)


(DDX8)


DEAD/H (Asp-Glu-Ala-
3
L13848
+
+
+
+

+


Asp/His) box polypeptide 9


(RNA helicase A, nuclear


DNA helicase II; leukophysin)


(DDX9)


DEAD/H (Asp-Glu-Ala-
1
AF000985

+
+

+


Asp/His) box polypeptide, Y


chromosome (DBY)


Death associated protein 3
2
X83544
+
+
+
+
+
+


(DAP3)


death effector domain-
1
AF083236

+
+
+

+


containing protein (DEDD)


death-associated protein 6
2
AF039136

+
+
+

+


(DAXX)


dedicator of cyto-kinesis 2
4
D86964
+
+

+

+


(DOCK2)


defender against cell death 1
1
D15057


+

+
+


(DAD1)


Defensin, alpha 1, myeloid-
4
L12690



+
+
+


related sequence (DEFA1)


DEK gene (D6S231E)
1
X64229
B

+

+


delta sleep inducing peptide,
4
Z50781
+
+
+
+

+


immunoreactor (DSIPI)


dendritic cell protein (GA17)
3
AF064603
+
+
+
+

+


deoxycytidine kinase (DCK)
1
M60527


deoxyribonuclease II,
3
AB004574


lysosomal (DNASE2)


DGS-I
2
L77566

+


diacylglycerol kinase
3
D16440


diacylglycerol kinase alpha
3
AF064771

+


(DAGK1) (clone 24)


diacylglycerol kinase alpha
1
AF064771


(DAGK1) (clone 24) (low


match)


diaphanous (Drosophila,
1
AF051782
B, monocyte
+
+

+
+


homolog) 1 (DIAPH1)


stimulated


diaphorase (NADH)
1
Y09501
+
+
+
+
+
+


(cytochrome b-5 reductase)


(DIA1)


differentiated Embryo
1
AB004066

+


+
+


Chondrocyte expressed gene 1


(DEC1)


differentiated Embryo
1
AB004066


Chondrocyte expressed gene 1


(DEC1) (low match)


differentiation antigen CD20
1
L23415


DiGeorge syndrome critical
1
X84076

+
+


+


region gene 2 (DGCR2)


dihydrolipoamide
2
J03620

+


+
+


dehydrogenase (E3


component of pyruvate


dehydrogenase complex, 2-


oxo-glutarate complex,


branched chain keto acid


dehydrogenase complex)


(DLD)


dihydrolipoamide S-
1
Y00978
B
+


+


acetyltransferase (E2


component of pyruvate


dehydrogenase complex)


(DLAT)


dihydropyrimidinase-like 2
1
D78013

+
+

+
+


(DPYSL2)


dinG gene
1
Y10571


diptheria toxin resistance
3
AF053003
B
+
+

+
+


protein required for


diphthamide biosynthesis


(Saccharomyces)-like 2


(DPH2L2)


disintegrin-protease (non-
1
Y13323


exact 72%)


DJ-1 protein
2
AF021819
+
+
+
+

+


Dmx-like 1 (DMXL1)
1
AJ005821
+

+
+


DNA (cytosine-5-)-
3
X63692
T activated,
+


+
+


methyltransferase 1 (DNMT1)


lymphoma


DNA fragmentation factor, 40 kD,
1
AF064019


beta subunit (DFFB)


DNA fragmentation factor, 45 kD,
2
U91985
T
+
+


+


alpha subunit (DFFA)


DNA mismatch repair protein
1
U17840


(hMLH1)


DNA segment on
3
M64241
+
+
+
+
+
+
high in many libraries


chromosome X (unique) 648


expressed sequence


DNA segment, single copy
3
M73547

+
+
+

+


probe LNS-CAI/LNS-CAII


(deleted in polyposis


(D5S346)


DNA-damage-inducible
1
L24498


transcript 1 (DDIT1) (low


match)


DnaJ protein
1
AJ001309


DnaJ protein
1
AJ001309


docking protein 2, 56 kD
1
AF034970


(DOK2)


dolichyl-
1
D89060
+
+
+
+
+
+
activated T cell


diphosphooligosaccharide-


protein glycosyltransferase


(DDOST)


dolichyl-phosphate
1
D86198
T activated
+
+

+


mannosyltransferase


polypeptide 1, catalytic


subunit (DPM1)


down-regulated by activation
1
AJ223183




+


(immunoglobulin superfamily)


(DORA)


down-regulated in adenoma
1
P40879


DRA (low match)


D-type cyclin-interacting
1
AF082569
B



+
+


protein 1 (DIP1)


dual specificity phosphatase 1
4
X68277
+
+
+
+
+
+


(DUSP1)


dual specificity phosphatase
1
AF023917
+
+
+
+

+


11 (RNA/RNP complex 1-


interacting) (dusp11)


dual specificity phosphatase 3
1
L05147

+
+

+
+


(vaccinia virus phosphatase


VH1-related) (DUSP3)


dual specificity phosphatase 6
6
X93920
+
+
+
+
+
+


(DUSP6)


dynactin 1 (p150, Glued
3
X98801


(Drosophila) homolog)


(DYTN1)


dynactin 1 (p150, Glued
1
X98801
B
+
+


(Drosophila) homolog)


(DYTN1) (low match)


dynamin 2 (DNM2)
1
L36983


dynamitin (dynactin complex
1
U50733


50 kD subunit) (DCTN-50)


(non-exact 88%)


dynein, axonemal, heavy
1
X99947


polypeptide 17-like (non-


exact, 57% aa)


dynein, cytoplasmic, light
1
AF035812
B
+
+


+


intermediate polypeptide 2


(DNCLI2)


dynein, cytoplasmic, light
1
AF035812


intermediate polypeptide 2


(DNCLI2) (non-exact, 69%)


dyskeratosis congenita 1,
1
U59151
B
+


+
+


dyskerin (DKC1)


dystonia 1, torsion (autosomal
1
AF007871

+
+
+

+


dominant) (DYT1)


dystrobrevin, beta (DTNB)
1
AF022728

+


dystrophia myotonica-
1
L19267

+
+

+
+


containing WD repeat motif


(DMWD)


dystrophia myotonica-protein
1
L08835
+
+
+


+


kinase (DMPK)


dystrophin (muscular
1
X14298


dystrophy, Duchenne and


Becker types) (DMD) (low


match, 59% aa)


E1B-55 kDa-associated protein
1
AJ007509
W
+
+

+
+


E2F transcription factor 3
2
D38550

+
+
+
+
+


(E2F3)


E2F transcription factor 4,
1
X86096
B
+


+


p107/p130-binding (E2F4)


E2F transcription factor 5,
2
U15642
+
+

+

+


p130-binding (E2F5)


E74-like factor 1 (ets domain
1
M82882
B

+

+
+


transcription factor) (ELF1)


E74-like factor 4 (ets domain
3
U32645

+
+


+


transcription factor) (ELF4)


E74-like factor 4 (ets domain
1
U32645


transcription factor) (ELF4)


(non-exact, 71%)


early development regulator 2
4
U89278
+
+
+
+

+


(homolog of polyhomeotic 2)


(EDR2)


EBV induced G-protein
1
L08177
W


coupled receptor (EBI2)


ecotropic viral integration site
3
M60830

+

+


2B (EVI2B)


ectin, galactoside-binding,
1
J04456





+


soluble, 1 (galectin 1)


(LGALS1)


EGF-like-domain, multiple 4
1
AB011541


(EGFL4)


eIF-2-associated p67 homolog
3
U13261
B
+



+


elastin (supravalvular aortic
1
M24782

+
+


stenosis, Williams-Beuren


syndrome) (ELN) (low match)


elav-type RNA-binding
3
U69546


protein (ETR-3)


electron-transfer-flavoprotein,
2
J04058

+


alpha polypeptide (glutaric


aciduria II) (ETFA)


ELK3, ETS-domain protein
2
Z36715


+


+


(SRF accessory protein 2)


(ELK3)


elongation factor 1-beta
1
L26404


elongation factor Ts
1
AF110399


(mitochondrial protein)


elongation factor Tu-nuclear
1
X84694


encoded mitochondrial


eMDC II protein
1
AJ242015.1


ems1 sequence (mammary
1
M98343

+
+

+
+


tumor and squamous cell


carcinoma-associated (p80/85


src substrate) (EMS1)


endogenous retroviral element
1
Z70664


HC2


endosulfine alpha (ENSA)
1
X99906
T
+


endothelial differentiation,
2
M31210

+
+
+

+


sphingolipid G-protein-


coupled receptor, 1 (EDG1)


endothelial differentiation,
1
M31210


sphingolipid G-protein-


coupled receptor, 1 (EDG1)


(low match 66%)


endothelial monocyte-
1
U10117
+
+
+
+

+


activating polypeptide


(EMAPII)


enolase 1, (alpha) (ENO1)
12
M14328
+
+
+
+
+
+


enolase 2, (gamma, neuronal)
1
X51956

+


(ENO2)


enolase-alpha
1
D28437


enoyl Coenzyme A hydratase
2
U16660


1, peroxisomal (ECH1)


enoyl Coenzyme A hydratase,
1
D13900
+
+
+
+
+
+


short chain, 1, mitochondrial


(ECHS1)


ENOYL-COA HYDRATASE,
1
P30084


MITOCHONDRIAL


PRECURSOR (SHORT


CHAIN ENOYL-COA


HYDRATASE) (SCEH)


(ENOYL-COA


HYDRATASE 1) (low match,


non-exact 56%)


epidermal growth factor
2
U07707

+

+

+


receptor pathway substrate 15


(EPS15)


EPIDIDYMAL SECRETORY
2
Q15668


PROTEIN E1 PRECURSOR


(EPI-1) (HE1)


(EPIDIDYMAL


SECRETORY PROTEIN


14.6) (ESP14.6)


epithelial membrane protein 3
1
U87947
+
+
+
+

+


(EM[P3)


Epoxide hydrolase 1,
1
L29766





+


microsomal (xenobiotic)







only


(EPHX1)


ERCC2 (=L47234)
1
X52221


ERF-2
3
U07802
+
+
+
+

+
high in gall bladder


ERp28 protein
1
X94910
+
+
+
+

+


erythrocyte membrane protein
2
M81635


erythroleukemic cells K562
2
L25343


EST (Hs.189509)
2
U24166


estrogen receptor-related
1
L38487


protein (hERRa1)


ESTs, Highly similar to
1
X66503
B, T
+
+


ADENYLOSUCCINATE


SYNTHETASE


ESTs, Moderately similar to
1
U28811
+
+
+
+

+


cysteine-rich fibroblast growth


factor receptor


ET binding factor 1 (SBF1)
1
U93181
+
+



+


ets domain protein ERF
1
U15655
+
+
+
+

+


eukaryotic translation
326
X03558
T
+
+


+


elongation factor 1 alpha 1


(EEF1A1)


eukaryotic translation
1
X03558


elongation factor 1 alpha 1


(EEF1A1) (low match)


eukaryotic translation
1
X03558


elongation factor 1 alpha 1


(EEF1A1) (low match)


eukaryotic translation
5
X60489
+
+
+
+

+


elongation factor 1 beta 2


(EEF1B2)


eukaryotic translation
1
Z21507
+
+
+
+
+
+


elongation factor 1 delta


(guanine nucleotide exchange


protein) (EEF1D)


eukaryotic translation
31
Z11531


elongation factor 1 gamma


(EEF1G)


eukaryotic translation
2
X51466

+



+


elongation factor 2 (EEF2)


eukaryotic translation
1
J02645


initiation factor 2, subunit 1


(alpha, 35 kD) (EIF2S1)


eukaryotic translation
1
M29536


initiation factor 2, subunit 2


(beta, 38 kD) (EIF2S2)


eukaryotic translation
3
L19161

+
+


initiation factor 2, subunit 3


(gamma, 52 kD) (EIF2S3)


eukaryotic translation
2
U78311


initiation factor 3, subunit 10


(theta, 150/170 kD) (EIF3S10)


eukaryotic translation
3
U36764
+
+
+
+
+
+
high in white blood


initiation factor 3, subunit 2








cells


(beta, 36 kD) (EIF3S2)


eukaryotic translation
6
U54559
+
+
+
+

+
high in spleen


initiation factor 3, subunit 3


(gamma, 40 kD) (EIF3S3)


eukaryotic translation
9
AF020833

+
+
+

+


initiation factor 3, subunit 4


(delta, 44 kD) (EIF3S4)


eukaryotic translation
4
U94175
+
+
+
+

+
high in bladder


initiation factor 3, subunit 6


(48 kD) (EIF3S6)


eukaryotic translation
1
U62962

+
+
+

+
Highly represented


initiation factor 3, subunit 6








(1.4833 pct) in library


(EIF3S6)








36 human gall bladder


eukaryotic translation
3
U54558
+
+
+
+

+


initiation factor 3, subunit 7


(zeta, 66/67 kD) (EIF3S7)


eukaryotic translation
5
U46025
+
+
+
+
+
+
high in testis


initiation factor 3, subunit 8,


110 KD (EIF3S8)


eukaryotic translation
1
AF012088


initiation factor 4 gamma, 1


(EIF4G)


eukaryotic translation
1
AF012088


initiation factor 4 gamma, 1


(EIF4G) (low match)


eukaryotic translation
2
D12686


initiation factor 4 gamma, 1


(EIF4G1)


eukaryotic translation
6
U73824
+
+
+
+
+
+


initiation factor 4 gamma, 2


(EIF4G2)


eukaryotic translation
2
U76111
+
+
+
+
+
+


initiation factor 4 gamma, 2


(EIFG2)


eukaryotic translation
29
D13748


initiation factor 4A, isoform 1


(EIF4A1)


eukaryotic translation
11
D30655
+
+
+
+
+
+


initiation factor 4A, isoform 2


(EIF4A2)


eukaryotic translation
18
X55733
+
+
+
+

+


initiation factor 4B (EIF4B)


eukaryotic translation
1
P06730


initiation factor 4E (EIF4E)


Eukaryotic translation
3
L36056
T, B
+


+
+


initiation factor 4E binding


protein 2 (EIF4EBP2)


eukaryotic translation
2
Q15056


initiation factor 4H (EIF4H)


eukaryotic translation
2
U49436
+
+
+
+
+
+


initiation factor 5 (EIF5)


eukaryotic translation
2
U90176
+
+
+
+

+


termination factor 1 (ETF1)


EV12 protein
1
M55266

+


Ewing sarcoma breakpoint
1
X66899
+
+
+
+

+


region 1 (EWSR1)


EWS/FLI1 activated transcript
2
AF020264


2 homolog (EAT-2)


EWS-EIA-F chimeric protein
1
U35622


excision repair cross-
1
M28650
+
+
+
+

+


complementing rodent repair


deficiency, complementation


group 1 (includes overlapping


antisense sequence) (ERCC1)


excision repair cross-
1
X69978

+
+
+

+


complementing rodent repair


deficiency, complementation


group 5 (xeroderma


pigmentosum,


complementation group G


(Cockayne syndrome))


(ERCC5)


exostoses (multiple)-like 3
1
AF001690

+
+
+

+


(EXTL3)


F11
1
X77744



+


F1-ATPase beta subunit (F-1
2
X03559


beta)


Fanconi anaemia group A
2
Z83095


Fanconi anemia,
1
X99226
+
+
+
+


complementation group A


(FANCA)


far upstream element (FUSE)
2
U05040
+

+


+


binding protein 1 (FUBP1)


farnesyl diphosphate synthase
1
J05262
+
+
+
+

+


(farnesyl pyrophosphate


synthetase,


dimethylallyltranstransferase,


geranyltranstransferase)


(FDPS)


farnesyl-diphosphate
2
X69141
+
+
+
+
+
+


farnesyltransferase 1 (FDFT1)


farnesyltransferase, CAAX
2
L00635

+
+


box, beta (FNTB)


Fas ligand (gene and promoter
1
AF044583


region)


Fas-ligand associated factor 1
1
U70667


fatty-acid-Coenzyme A ligase,
4
D10040
+
+
+
+
+
+


long-chain 1 (FACL1)


Fc fragment of IgA, receptor
1
X54150


for (FCAR)


Fc fragment of IgE, high
1
M33195
+
+
+
+

+


affinity I, receptor for; gamma


polypeptide (FCER1G)


Fc fragment of IgE, low
2
X04772
+
+


affinity II, receptor for


(CD23A) (FCER2)


Fc fragment of IgG, low
6
M31932
+
+
+
+
+
+


affinity IIa, receptor for


(CD32)


Fc fragment of IgG, low
1
X62572
+
+
+
+
+
+


affinity IIa, receptor for


(CD32) (FCGR2A)


Fc fragment of IgG, low
34
X07934
+
+
+
+

+


affinity IIIa, receptor for


(CD16) (FCGR3A)


Fc fragment of IgG, receptor,
3
U12255

+
+
+
+
+
high in many libraries


transporter, alpha (FCGRT)


fc-fgr
1
Z13983


Fc-gamma-receptorIIIB
2
M90746


(FCGR3B)


feline sarcoma (Snyder-
3
X06292


Theilen) viral (v-fes)/Fujinamiavian


sarcoma (PRCII) viral


(v-fps) oncogene


homolog(FES) c-fes/fps)


female sterile homeotic-
2
X96670
+
+
+
+

+


related gene 1 (mouse


homolog) (FSRG1)


ferritin L-chain
9
Y09188


ferritin, heavy polypeptide 1
4
M11146
+
+
+
+
+
+


(FTH1)


fertilin alpha pseudogene
1
Y09232


fetal Alzheimer antigen
2
U05237

+


(FALZ)


fetal Ig heavy chain variable
1
M34024


region


fibrillarin (FBL)
1
X56597
+
+
+
+
+
+


fibrinogen-like protein 2
3
Z36531



+


(T49)


fibroblast growth factor
1
M35718
+
+
+
+
+
+


receptor 2 (bacteria-expressed


kinase, keratinocyte growth


factor receptor, craniofacial


dysostosis 1, Crouzon


syndrome) syndrome, Pfeiffer


syndrome, Jackson-Weiss)


(FGFR2)


ficolin (collagen/fibrinogen
19
D83920



+

+


domain-containing) 1 (FCN1)


filamin A, alpha (actin-
2
X53416


binding protein-280) (FLNA)


filamin B, beta (actin-binding
1
AF043045

+
+

+


protein-278) (FLNB)


Finkel-Biskis-Reilly murine
2
X65923
+
+
+
+
+
+
Highly represented in


sarcoma virus (FBR-MuSV)








intraepithelial


ubiquitously expressed (fox








neoplasia and


derived); ribosomal protein








invasive prostate


S30 (FAU)








tumor


FK-506 binding protein
1
M80199
+
+
+
+

+


FK506-binding protein 1A
2
M34539


(12 kD) (FKBP1A)


FK506-binding protein 1B
1
M92423

+

+

+


(12.6 kD) (FKBP1B)


FK506-binding protein 5
4
U71321

+
+
+

+


(FKBP5)


Flightless I (Drosophila)
3
U80184

+


homolog (FLII)


Flightless I (Drosophila)
1
U80184


homolog (FLII) (low match)


FLN29 (FLN29)
2
AB007447

+

+

+


flotillin 2 (FLOT2)
5
M60922
+
+
+
+
+
+


folate receptor 2 (fetal)
1
AF000380

+
+
+

+


(FOLR2)


forkhead (Drosophila)
1
AF032886
+
+

+

+


homolog (rhabdomyosarcoma)


like 1 (FKHRL1)


Formyl peptide receptor 1
9
M60627
+
+
+
+

+


(FPR1)


formyl peptide receptor-like 1
1
M84562






Found only in libraries


(FPRL1)








from placenta


formyl peptide receptor-like 1
1
M84562


(FPRL1) (low score)


fragile X mental retardation 1
1
L29074
+
+

+

+


(FMR1)


fragile X mental retardation,
1
U25165
+
+
+
+


autosomal homolog 1 (FXR1)


Friend leukemia virus
3
M93255
+
+


integration 1 (FLI1)


fructose-bisphosphatase 1
1
D26054



+

+


(FBP1)


FSHD-associated repeat
1
U85056


DNA, proximal region


fucose-1-phosphate
1
AF017445

+
+
+


guanylyltransferase (FPGT)


full length insert cDNA clone
1
AF086122


ZA78A09


full length insert cDNA
1
AF075061


YP07G10


fumarate hydratase (FH)
1
U59309

+
+
+

+


FUS (low match)
1
X99006


FYN-binding protein (FYB-
16
U93049

+

+


120/130) (FYB)


G alpha interacting protein
1
X91809


(GAIP) (low score)


G protein beta subunit-like
2
D28398


protein 12.3


G protein-coupled receptor 64
1
X81892



+


(HE6) (non-exact 59%)


G protein-coupled receptor
2
L16862
+
+
+


+


kinase 6 (GPRK6)


G1 to S phase transition 1
2
X17644

+
+
+
+
+


(GSPT1)


GA-binding protein
1
D13316

+
+
+
+
+


transcription factor, beta


subunit 2 (47 kD) (GABPB2)


galactose-1-phosphate
2
M60091


uridylyltransferase (GALT)


galactosidase, beta 1 (GLB1)
3
M27508

+


+
+


galactosyltransferase
1
M13701


(=X13223 N-


acetylglucosamide-(beta 1-4)-


galactosyltransferase)


galectin-9 isoform
1
AB006782
+


+

+


gamma2-adaptin (G2AD)
1
AF068706
+
+

+

+


gamma-actin
2
M37130


gamma-aminobutyric acid
2
AJ012187

+
+


+


(GABA) B receptor 1


(GABBR1)


GATA-binding protein 2
1
M68891



+

+


(GATA2)


GATA-binding protein 3
1
M69106


+
+

+


(GATA3)


GCN5 (general control of
3
D64007
+
+
+
+

+


amino-acid synthesis, yeast,


homolog)-like 1 (GCN5L1)


GDP dissociation inhibitor 1
1
D45021
+
+
+
+

+
high in adult brain


(GDI1)


GDP dissociation inhibitor 2
4
Y13286


(GCI2)


GDS-related protein
4
U68142
+
+
+
+

+


(HKE1.5)


gelsolin (amyloidosis, Finnish
3
X04412

+
+
+
+
+


type) (GSN)


general transcription factor II,
4
Y14946
+
+
+
+
+
+


I (GTF2I)


general transcription factor II,
1
AF038968
+
+
+
+
+
+
high in fetal brain


i, pseudogene 1 (GTF2IP1)


general transcription factor
4
X64037
+
+
+
+

+


IIF, polypeptide 1 (74 kD


subunit) (GTF2F1)


general transcription factor
2
Z30093
B, T


IIH, polypeptide 3 (34 kD


subunit) (GTF2H3)


general transcription factor
3
Y07595

+

+

+


IIH, polypeptide 4 (52 kD


subunit) (GTF2H4)


general transcription factor
1
U14134
+
+

+

+


IIIA (GTF3A)


general transcription factor
1
U02619

+

+


IIIC, polypeptide 1 (alpha


subunit, 220 kD) (GTF3C1)


general transcription factor
3
D13636
+
+
+
+
+
+


IIIC, polypeptide 2 (beta


subunit, 110 kD) (GTF3C2)


germline immunoglobulin
1
L06612


heavy chain (IGHV@)


germline immunoglobulin
1
X92236


heavy chain, variabl region


germline immunoglobulin
1
X92343


heavy chain, variable region,


(21-2)


GLE1 (yeast homolog)-like,
1
AF058922

+
+


RNA export mediator


(GLE1L)


glia maturation factor, beta
1
AB001106
+
+

+

+


(GMFB)


glioma-associated oncogene
1
X07384


homolog (zinc finger protein)


(GLI)


glioma-associated oncogene
1
X07384


homolog (zinc finger protein)


(GLI) (low score)


globin, alpha 2
1
V00516


glucocorticoid receptor
1
M32284


(=M69104)


glucocorticoid receptor (GRL)
2
U80947
+
+
+
+

+


glucos phosphate isomerase
1
L09105


(CONTAINS LARGE


REPEAT)


glucosamine (N-acetyl)-6-
1
Z12173
+


sulfatase (Sanfilippo disease


IIID) (GNS)


glucosamine (N-acetyl)-6-
1
Z12173


sulfatase (Sanfilippo disease


IIID) (GNS) (non-exact 56%)


glucose transporter-like
1
M20681

+
+
+
+
+


protein-III (GLUT3)


glucose transporter-like
1
M20681


protein-III (GLUT3) (low


match)


glucosidase, alpha; acid
1
Y00839
+
+

+

+


(Pompe disease, glycogen


storage disease type II) (GAA)


glucosidase, beta; acid
1
K02920
+
+
+
+

+


(includes glucosylceramidase)


(GBA)


glutamate dehydrogenase 1
1
M20867

+
+
+
+
+


(GLUD1)


glutamate-ammonia ligase
12
X59834
+
+
+
+

+


(glutamine synthase) (GLUL)


glutamate-ammonia ligase
1
Y00387


(glutamine synthase) (GLUL)


(low score)


glutamate-cysteine ligase
1
M90656



+


(gamma-glutamylcysteine


synthetase), catalytic (72.8 kD)


(GLCLC)


glutamine cyclotransferase
1
X71125

+
+


glutamine-fructose-6-
1
M90516

+

+


phosphate transaminase 1


(GFPT1)


glutaminyl-tRNA synthetase
1
X72396


glutaminyl-tRNA synthetase
6
X76013
+
+
+
+

+


(QARS)


glutamyl-prolyl-tRNA
1
X54326


synthetase (EPRS)


glutathione peroxidase 1
2
M21304
+
+
+
+
+
+


(GPX1)


glutathione peroxidase 4
1
X71973
+
+
+
+

+


(phospholipid


hydroperoxidase) (GPX4)


glutathione S-transferase pi
1
U30897

+
+
+
+
+


(GSTP1)


glutathione S-transferase
1
AF070657


subunit 13 homolog


glyceraldehyde-3-phosphate
12
J02642




+


dehydrogenase (GAPD)


glycogenin (GYG)
1
U31525

+
+
+

+


glycophorin C (Gerbich blood
1
X12496

+
+
+

+


group) (GYPC)


glycoprotein M6B (GPM6B)
1
U45955

+
+


glycyl-tRNA synthetase
1
U09587

+
+
+

+


(GARS)


glyoxalase I (lactoyl
1
L07837
+
+
+
+

+


glutathione lyase) (GLYI)


golgi autoantigen, golgin
1
U51587

+

+


subfamily a, 1 (GOLGA1)


golgi autoantigen, golgin
1
L06147


subfamily a, 2 (GOLGA2)


(non-exact, 70%)


golgi autoantigen, golgin
1
U31906


subfamily a, 4 (GOLGA4)


golgi autoantigen, golgin
1
X75304

+
+
+

+


subfamily b, macrogolgin


(with transmembrane signal),


1 (GOLGB1)


gp25L2 protein
4
X90872


grancalcin
8
M81637

+
+
+


granulin (GRN)
16
X62320
+
+
+
+

+


granulin (GRN) (low match)
1
X62320


Granulysin (NKG5)
5
M85276
+




+


granzyme A (granzyme 1,
1
M18737
+
+
+
+

+


cytotoxic T-lymphocyte-


associated serine esterase 3)


(GZMA)


GRB2-related adaptor protein
1
U52518
T only


(GRAP)


Grb2-related adaptor protein 2
1
AF090456
T



+


(GRAP2)


GRO1 oncogene (melanoma
1
X54489



+

+


growth stimulating activity,


alpha) (GRO1)


growth arrest and DNA-
1
S40706


damage-inducible gene


(GADD153)


growth arrest-specific 7
4
AB007854

+
+


(GAS7)


growth factor receptor-bound
1
X62852
B
+


+
+


protein 2 (GRB2)


GS1 (protein of unknown
1
M86934

+
+
+


function)


GS3955
4
D87119

+
+
+

+


GTP binding protein 1
1
U87964

+
+
+


(GTPBP1)


GTP binding protein similar
1
U87791

+
+
+

+


to S. cerevisiae HBS1 (HBS1)


GTPase activating protein-like
1
AB011110

+
+
+

+
high fetal brain


(GAPL)


GTP-binding protein (low
1
Z49068


match)


GTP-binding protein G(K),
1
P08754


alpha subunit (=G(I) ALPHA-


3)(=GTP-binding regulatory


protein Gi alpha-3 chain)


Gu protein (GURDB)
2
U41387
+

+
+

+


guanine nucleotide binding
1


protein


guanine nucleotide binding
4
J03004
+
+
+
+

+


protein (G protein), alpha


inhibiting activity polypeptide


2 (GNAI2)


guanine nucleotide binding
7
M20597
+
+
+
+

+


protein (G protein), alpha


inhibiting activity polypeptide


3 (GNAI3)


guanine nucleotide binding
2
X04409
B, T
+


+
+


protein (G protein), alpha


stimulating activity


polypeptide 1 (GNAS1)


guanine nucleotide binding
1
Z18859


protein (G protein), alpha


transducing activity


polypeptide 2 (GNAT2)


guanine nucleotide binding
2
AF017656

+
+
+

+


protein (G protein), beta 5


(GNB5)


guanine nucleotide binding
5
M36430
+
+
+
+
+
+


protein (G protein), beta


polypeptide 1 (GNB1)


guanine nucleotide binding
2
AF011496

+
+
+


protein (G protein), q


polypeptide (GNAQ)


guanine nucleotide binding
1
L25665
+
+
+
+

+


protein-like 1 (GNL1)


guanine nucleotide exchange
1
L13857
+
+
+
+


factor


guanine nucleotide regulatory
1
X15610
+
+
+
+

+


factor (LFP40)


guanine nucleotide regulatory
1
U72206
+
+
+
+

+


factor (LFP40)


GUANINE NUCLEOTIDE-
1
P25388


BINDING PROTEIN BETA


SUBUNIT-LIKE PROTEIN


12.3 (P205) (RECEPTOR OF


ACTIVATED PROTEIN


KINASE C 1) (RACK1)


GUANINE-
1
U10860


+


MONOPHOSPHATE


SYNTHETASE (GMPS)


guanosine monophosphate
1
M24470


reductase (GMPR) (non-exact,


72%)


guanosine-diphosphatase like
1
AF016032


protein


guanylate binding protein 1,
2
M55542

+
+
+
+
+


interferon-inducible, 67 kD


(GBP1)


guanylate binding protein 2,
6
M55543
+
+
+
+

+


interferon-inducible (GBP2)


H2A histone family, member
1
Z83742


C (H2AFC)


H2A histone family, member
2
AF041483
+
+
+
+

+


Y (H2AY)


H2B histone family, member
2
Z80783
+
+
+
+
+
+
high in adrenal gland


L (H2BFL)








tumor


h2-calponin
1
D86059


H-2K binding factor-2
1
L08904

+
+
+

+


H3 histone family, member K
1
Z83735


(H3FK)


H3 histone, family 3A
7
M11353
+
+
+
+

+
high in ovary


(H3F3A)


H3 histone, family 3B
15
Z48950
+
+
+
+

+
high in endothelial cells


(H3.3B) (H3F3B)








endothelial cells


hbc647
1
U68494

+
+
+
+


heat shock 27 kD protein 1
1
U12404

+
+

+
+


(HSPB1)


heat shock 40 kD protein 1
4
D85429
+
+
+
+
+
+
high in testis


(HSPF1)


heat shock 60 kD protein 1
3
M22382
+
+
+
+
+
+


(chaperonin) (HSPD1)


heat shock 70 kD protein 1
7
M59828
+
+
+
+
+
+
high in activated


(HSPA1A)








T cells


heat shock 70 kD protein 5
13
X87949

+
+

+


(glucose-regulated protein,


78 kD) (HSPA5)


heat shock 70 kD protein 6
4
X51757
+
+
+


(HSP70B′) (HSPA6)


heat shock 70 kD protein 9B
2
L15189

+
+
+
+
+


(mortalin-2) (HSPA9B)


HEAT SHOCK COGNATE
1
P11142


71 KD PROTEIN


heat shock factor binding
2
AF068754


protein 1 (HSBP1)


heat shock protein 90
13
M27024
+
+
+
+
+
+
high in many libraries


heat shock protein, DNAJ-like
1
D13388

+
+

+
+


2 (HSJ2)


Hect (homologous to the E6-
1
U50078

+
+
+


AP (UBE3A) carboxyl


terminus) domain and RCC1


(CHC1)-like domain (RLD) 1


(HERC1)


hect domain and RLD 2
1
AB002391
+
+
+
+

+


(HERC2)


helicase-like protein (HLP)
1
X98378
+
+

+

+


helix-loop-helix protein HE47
1
M65214





+


(E2A)


hematopoietic cell-specific
18
X16663
+

+
+

+


Lyn substrate 1 (HCLS1)


heme oxygenase (decycling) 1
1
X06985

+

+
+
+


(HMOX1)


HEMOGLOBIN ALPHA
1
P19015


CHAIN


hemoglobin beta (beta globin)
5
AF117710


hemoglobin, alpha 1 (HBA1)
301
V00491


+

+
+


hemoglobin, alpha 1 (HBA1)
1
V00491


(low match)


hemoglobin, alpha 1 (low
1
V00493


match)


hemoglobin, alpha 1 (non-
1
J00153


exact, 76%)


hemoglobin, alpha 1 (non-
1
V00493


exact, 82%)


hemoglobin, beta (HBB)
129
V00497
+
+
+
+
+
+
high in many libraries


hemoglobin, beta (HBB) (low
1
V00497


match)


hemoglobin, beta (HBB) (low
1
L48220


match)


hemokine (C—X—C motif),
1
D10924
+
+
+
+

+


receptor 4 (fusin) (CXCR4)


hemopoietic cell kinase
5
M16591



+

+


(HCK)


hepatitis C-associated
2
D28908


microtubular aggregate


protein p44


hepatoma-derived growth
1
D16431
+
+
+
+

+


factor


Hermansky-Pudlak syndrome
2
U65676


(HPS)


HERV-E integrase (non-exact
1
AF026246


76% aa)


heterogeneous nuclear protein
2
S63912

+
+
+

+


similar to rat helix


destabilizing protein (FBRNP)


heterogeneous nuclear
4
M16342


ribonucleoprotein (C1/C2)


(HNRPC)


heterogeneous nuclear
1
M65028
+
+
+
+
+
+


ribonucleoprotein A/B


(HNRPAB)


heterogeneous nuclear
20
X12671
+
+
+
+
+
+
High in alveolar


ribonucleoprotein A1








rhabdomyosarcoma


(HNRPA1)


heterogeneous nuclear
3
M29064
+
+
+
+
+
+
High in activated T


ribonucleoprotein A2/B1








cell, fetal brain


(HNRPA2B1)


heterogeneous nuclear
2
D55673
+
+
+
+
+
+


ribonucleoprotein D (hnRNP


D)


heterogeneous nuclear
5
D89092
+
+
+
+
+
+


ribonucleoprotein D-like


(HNRPDL)


heterogeneous nuclear
1
L28010
+
+
+
+

+


ribonucleoprotein F (HNRPF)


heterogeneous nuclear
1
L28010


ribonucleoprotein F (HNRPF)


(83%)


heterogeneous nuclear
2
Z23064

+
+
+

+


ribonucleoprotein G


(HNRPG)


heterogeneous nuclear
3
P55795


ribonucleoprotein H


(HNRPH) (FTP-3)


heterogeneous nuclear
1
P31943


ribonucleoprotein H


(HNRPH) (low match)


heterogeneous nuclear
2
L22009
+
+
+
+

+


ribonucleoprotein H1 (H)


(HNRPH1)


heterogeneous nuclear
21
S74678
+
+
+
+
+
+


ribonucleoprotein K


(HNRPK)


heterogeneous nuclear
1
AF000364

+
+
+
+
+


ribonucleoprotein R


(HNRPR)


heterogeneous nuclear
3
X65488
+
+
+
+
+
+


ribonucleoprotein U (scaffold


attachment factor A)


(HNRPU)


hexokinase 1 (HK1)
2
X66957

+
+
+

+


hexokinase 2 (HK2)
3
Z46376
+
+
+
+

+


hexokinase 3 (HK3)
2
U51333


hexosaminidase A (alpha
1
S62047


polypeptide) (HEXA


HGMP07I gene for olfactory
2
U76377


receptor


High density lipoprotein
2
M64098
+
+
+
+
+
+


binding protein (HDLBP)


high-mobility group
5
X12597
+
+
+
+
+
+


(nonhistone chromosomal)


protein 1 (HMG1)


high-mobility group
1
D63874


(nonhistone chromosomal)


protein 1 (HMG1) (non-exact


60%)


High-mobility group
2
M12623
+
+
+
+

+


(nonhistone chromosomal)


protein 17 (HMG17)


high-mobility group
2
M83665
+
+
+
+
+
+


(nonhistone chromosomal)


protein 2 (HMG2)


high-mobility group
2
L17131
+
+
+

+
+


(nonhistone chromosomal)


protein isoforms I and Y


high-risk humanpapilloma
1
AF090990.1


viruses E6 oncoproteins


targeted protein E6TP1 beta


(=AB007900 KIAA0440)


histidine ammonia-lyase
1
D16626


+,


(HAL)




only


histidyl-tRNA synthetase
2
Z11518
+
+
+
+
+
+


(HARS)


histocompatibility antigen
1
U31372


(HLA-Cw3), class I


histone deacetylase 1 (HDAC)
4
U50079
+
+
+
+

+


histone deacetylase 1
2
D50405
+
+
+
+

+


(HDAC1)


histone deacetylase 5 (NY-
1
AF039691

+
+


CO-9)


HK2 gene for hexokinase II
1
Z46362


HL9 monocyte inhibitory
2
U91928



+


receptor precursor


HLA class I heavy chain
1


(HLA-Cw*1701)


HLA class I locus C heavy
1
X58536


chain


HLA class II SB 4-beta chain
1
X03022


HLA class III region
1
U89335
+
+
+
+

+


containing NOTCH4 gene


HLA-A
1
Z72423


HLA-A
2
AJ006020


HLA-A*7402
1
AJ223060


HLA-A11
1
U02934


HLA-B
2
X75953


HLA-B
1
X83401


HLA-B
1
X78426


HLA-B associated transcript-1
1
Z37166
+
+
+
+
+
+


(D6S81E)


HLA-B associated transcript-2
2
M33509
+
+
+
+


(D6S51E)


HLA-B*1529
4
D44501


HLA-Bw72 antigen
119
L09736
+
+
+
+
+
+
high in many libraries


HLA-C gene (HLA-Cw*0701
1
D83957


allele)


HLA-Cw*0701
9
Z46810


HLA-Cw*0801
1
D64151


HLA-Cw*1203
1
D64146


HLA-DC classII
2
X00370


histocompatibility antigens


alpha-chain (=K01160)


HLA-DR alpha-chain
17
M60333
+
+
+
+
+
+
high in spleen


HLA-F (leukocyte antigen F)
3
X17093


+
+

+


HMG box containing protein 1
3
AF019214


hMLH1 (=U83845)
1
AB017806.1


Hmob33
3
Y14155


HMT1 (hnRNP
2
U80213
+
+
+
+

+


methyltransferase, S. cerevisiae)-


like 1 (HRMT1L1)


hnRNP C1/C2
2
D28382


homeobox (=X58250 Mouse
1
M60721


homeo box protein, put.


transcription factor involved


in embryogenesis and


hematopoiesis)


homeobox protein (HLX1)
1
U14326


(=M60721)


homeodomain-interacting
1
AF004849
+

+
+

+


protein kinase 3 (HIPK3)


homolog of Drosophila past
2
AF001434
+
+
+
+

+


(PAST)


homolog of yeast
3
D50916

+
+
+

+


(S. cerevisiae)


ufd2 (UFD2)


HPV16 E1 protein binding
1
U96131

+
+


+


protein


HRIHFB2157
1
AB015344

+
+


+


HRX-like protein
1
Y08836


(=AF010403 ALR)


hsc70 gene for 71 kd heat
3
Y00371


shock cognate protein


HSPC012
1
AF077036.1


HSPC021
1
AF077207.1


HsPex13p
1
U71374


htra2-beta-2
1
U87836
+
+
+
+

+


HU-K4
1
U60644


hunc18b2
1
U63533

+
+
+

+


HUNKI
1
Y12059
+
+

+
+
+


huntingtin-interacting protein
1
AF049528


HYPA/FBP11 (HYPA)


hVps41p (HVPS41)
1
U87309


hydroxyacyl-Coenzyme A
1
U04627

+
+

+


dehydrogenase/3-ketoacyl-


Coenzyme A thiolase/enoyl-


Coenzyme A hydratase


(trifunctional protein), alpha


subunit (HADHA)


hydroxyacyl-Coenzyme A
1
D16481
+
+
+
+

+


dehydrogenase/3-ketoacyl-


Coenzyme A thiolase/enoyl-


Coenzyme A hydratase


(trifunctional protein), beta


subunit (HADHB)


hydroxysteroid (17-beta)
1
U34879

+


+


dehydrogenase 1 (HSD17B1)


hypothetical protein
1


hypothetical protein
1


(AL008729) (dJ257A7.2)


hypothetical protein
1
U96629


(CIT987SK_2A8_1


chromosome 8)


hypothetical protein (clone
1
AF055004


24640)


hypothetical protein (clone
1
Z70222


ICRFp507G2490).


hypothetical protein
1
AL022238


(dJ1042K10.4) (non-exact


76%)


hypothetical protein
2
AL031432


(dJ465N24.1 similar to


predicted yeast and worm


proteins)


hypothetical protein
2
AL008730


(dJ487J7.1.1)


hypothetical protein
2
AL023653


(dJ753P9.2)


hypothetical protein
1
AL050131.1


(DKFZp586I111)


hypothetical protein
1
AL008729


(J257A7.2)


hypothetical protein
1
AB007900


(KIAA0440) (=AF026504


R. norvegicus SPA-1 like


protein)


hypothetical protein (L1H 3′
1


region)


hypothetical protein (S164)
1
P49756


hypothetical protein (similar
1
AF109907


to thrombospondin) (non-


exact 56%)


hypothetical protein 3
1


hypothetical protein B
1
U47926


(HSU47926) (non-exact,


56%)


hypothetical protein from
3
U50532
+
+
+
+

+


BCRA2 region (CG005)


hypoxia-inducible factor 1,
1
AF050115


alpha subunit (basic helix-


loop-helix transcription


factor) (HIF1A)


Ia-associated invariant
1
M13555


gamma-chain (clones lambda-


y (1,2,3))


iduronate 2-sulfatase (Hunter
2
M58342
+
+
+
+

+


syndrome) (IDS)


Ig heavy chain V region
1
L20779


(=D11016)


Ig heavy chain variable region
2
M34024


Ig heavy chain variable region
1
Z75378


(VH4DJ) (clone T14.4)


Ig heavy chain variable region
1
Z75392


(VH4DJ) (clone T22.18)


Ig J chain
1
M12378


Ig kappa
1
S49007


IG kappa light chain variable
1
X63398


region A20


Ig kappa light chain, V- and J-
1
D90158


region (=X59315)


Ig lambda light chain variable
1
Z85052


region (26-34ITIIIF120)


Ig mu-chain VDJ4-region
1
M16949


Ig rearranged anti-myelin
1
M29469


kappa-chain (V-J4-region,


hybridoma AE6-5)


Ig rearranged H-chain mRNA
2
M97920


V-region


Ig rearranged light-chain V
1
M74020


region (=D90158)


IGF-II mRNA-binding protein
1
U97188
+
+
+


3 (KOC1) (non-exact, 75%)


IgG Fc binding protein
1
D84239
+
+

+

+


(FC(GAMMA)BP)


IgG heavy chain variable
1
M83136


region (vH26)


IgM heavy chain (C mu,
1
X14939


membrane exons)


IkB kinase-beta (IKK-beta)
1
AF029684


IL-1 receptor type II
1
U14177


IL2-inducible T-cell kinase
2
S65186


(ITK)


immediate early protein
1
M62831
+

+
+

+


(ETR101)


immunogloblin light chain
1
D87018


(lambda)


Immunoglobulin (CD79A)
1
Y08915
B, T
+
+

+


binding protein 1 (IGBP1)


immunoglobulin C (mu) and
2
X57331


C (delta) heavy chain


(=K02878)


immunoglobulin G Fc
1
Z46223


receptor IIIB


immunoglobulin gamma 3
3
Y14737
+


+

+
high in many libraries


(Gm marker) (IGHG3)


immunoglobulin gamma
1
Z66542


heavy chain variable region


(=X61011)


immunoglobulin heavy chain
1
X62109


(VI-3B)


immunoglobulin heavy chain
1
X86356


J region


immunoglobulin heavy chain
2
X86355


J region, B1 haplotype


immunoglobulin heavy chain
1
AF062126


variable region (IGH) (clone


21u-48)


immunoglobulin heavy chain
1
AF062212


variable region (IGH) (clone


23u-1)


immunoglobulin heavy chain
2
M99641


variable region V1-18


(IGHV@) (=X60503)


immunoglobulin heavy chain
2
M99672


variable region V3-43


(IGHV@)


immunoglobulin heavy chain
3
M99649


variable region V3-7


(IGHV@)


immunoglobulin IgH heavy
1
U07986


chain Fd fragment


immunoglobulin kappa light
1
X58081


chain


immunoglobulin kappa light
1
X12686


chain V-segment A27


immunoglobulin light chain
1
D86990


immunoglobulin light chain
1
D86996


(low match)


immunoglobulin light chain
1
L29157


variable region (lambda IIIb


subgroup) from IgM


rheumatoid factor


immunoglobulin M heavy
1
S50735


chain V region = anti-lipid A


antibody


immunoglobulin mu (IGHM)
9
X57086
+
+

+

+


immunoglobulin mu binding
1
L24544
T
+


+


protein 2 (IGHMBP2)


immunoglobulin superfamily,
1
Z33642


member 2 (IGSF2)


Immunoglobulin VH mRNA
1
X61013


(487 bp) (=M99652


immunoglobulin heavy chain


variable region V3-11


(IGHV@))


imogen 38 (IMOGEN38)
1
Z68747

+
+
+

+


IMP (inosine monophosphate)
1
J05272
+
+
+
+


dehydrogenase 1 (IMPDH1)


IMP (inosine monophosphate)
2
L39210
+
+
+
+

+


dehydrogenase 2 (IMPDH2)


inc finger protein 151 (pHZ-
1
Y09723
+
+
+
+

+


67) (ZNF151)


inc finger protein, C2H2,
1
AF011573

+
+


rapidly turned over (ZNF20)


inducible poly(A)-binding
1
U33818
+
+
+
+

+


protein (IPABP)


inducible poly(A)-binding
1
U33818


protein (IPABP) (low match)


inducible protein (Hs.80313)
2
L47738
+
+
+
+

+


inhibitor of DNA binding 2,
4
M97796
+
+
+
+
+
+


dominant negative helix-loop-


helix protein (ID2)


inhibitor of kappa light
2
AF044195


polypeptide gene enhancer in


B-cells, kinase complex-


associated protein (IKBKAP)


inositol 1,3,4-trisphosphate
1
U51336
+
+
+
+
+
+


5/6-kinase


inositol 1,4,5 trisphosphate
1
U23850

+
+
+


receptor type 1 (ITPR1)


inositol 1,4,5-trisphosphate 3-
2
X57206
B
+
+

+


kinase B (ITPKB)


inositol monophosphatase
1
S38980


inositol polyphosphate-5-
2
U84400
+
+
+
+

+


phosphatase, 145 kD


(INPP5D)


Ins(1,3,4,5)P4-binding protein
1
X89399

+



+


insulin-like growth factor 2
5
Y00285
+
+
+
+

+


receptor (IGF2R)


integral membrane protein 1
1
L38961


+
+

+


(ITM1)


integral membrane protein 2C
1
AF038953
T

+

+
+


(ITM2C)


integral membrane protein
3
U61734
+
+
+
+
+
+


Tmp21-I (p23)


integrin beta 4 binding protein
2
AF047433


+


+


(ITGB4BP)


integrin, alpha 2b (platelet
3
M34480

+


+


glycoprotein IIb of IIb/IIIa


complex, antigen CD41B)


(ITGA2B)


integrin, alpha 5 (fibronectin
4
X06256
+
+
+

+
+


receptor, alpha polypeptide)


(ITGA5)


integrin, alpha L (antigen
6
Y00796


CD11A (p180), lymphocyte


function-associated antigen 1;


alpha polypeptide) (ITGAL)


integrin, alpha M
1
M18044


(complement


componentreceptor 3, alpha;


also known as CD11b (p170),


macrophage antigen alpha


polypeptide) (ITGAM)


integrin, alpha X (antigen
1
M81695
+
+



+


CD11C (p150), alpha


polypeptide) (ITGAX)


integrin, beta 1 (fibronectin
2
X07979


receptor, beta polypeptide,


antigen CD29 includes MDF2


MSK12) (ITGB1)


integrin, beta 2 (antigen CD18
32
M15395
+
+

+

+


(p95), lymphocyte function-


associated antigen 1;


macrophage antigen 1 (mac-1)


beta subunit) (ITGB2)


integrin, beta 7 (ITGB7)
1
M68892
+


Integrin-linked kinase (ILK)
1
U40282
+
+
+
+

+


intercellular adhesion
1
J03132
+


+
+
+


molecule 1 (CD54), human


rhinovirus receptor (ICAM1)


intercellular adhesion
1
X15606
+
+
+
+

+


molecule 2 (ICAM2)


intercellular adhesion
6
X69819
+




+


molecule 3 (ICAM3)


intercellular adhesion
1
L27670





+


molecule 4, Landsteiner-


Wiener blood group (ICAM4)


Interferon consensus sequence
1
M91196
W, T


binding protein 1 (ICSBP1)


lymphoma


Interferon consensus sequence
1
M91196


binding protein 1 (ICSBP1)


(low match)


interferon regulatory factor 2
4
X15949
+
+
+
+


(IRF2)


interferon regulatory factor1
4
L05072
+
+
+
+

+


(IRF1)


interferon regulatory factor5
1
U51127
+
+

+


(IRF5)


interferon, gamma-inducible
2
M63838
+
+
+
+

+


protein 16 (IFI16)


interferon, gamma-inducible
9
J03909
+
+

+

+


protein 30 (IFI30)


INTERFERON-INDUCED
1
P32455


GUANYLATE-BINDING


PROTEIN 1 (GUANINE


NUCLEOTIDE-BINDING


PROTEIN 1) (non-exact 62%)


interferon-induced protein 17
3
X84958

+
+
+

+


(IFI17)


interferon-induced protein 54
5
M14660


(IFI54)


interferon-inducible (1-8D)
5
X57351
T

+

+
+


interferon-inducible (1-8U)
1
X57352


+

+
+


interferon-related
5
Y10313

+
+


+


developmental regulator 1


(IFRD1)


interferon-stimulated
2
M87503

+

+

+


transcription factor 3, gamma


(48 kD) (ISGF3G)


interleukin 1 receptor, type II
1
U64094



+


(IL1R2)


Interleukin 10 receptor, beta
1
U08988
T activated

+


+


(I.10RB)


interleukin 12 receptor, beta 1
2
U03187
+





only found in T cell


(IL12RB1)


interleukin 13 receptor, alpha
2
Y09328

+
+
+
+
+


1 (IL13RA1)


interleukin 16 (lymphocyte
6
U82972

+


chemoattractant factor) (IL16)


interleukin 18 receptor 1
1
U43672


(IL18R1)


interleukin 2 receptor, beta
9
M26062


(IL2RB)


interleukin 2 receptor, gamma
6
D11086
+

+


+


(severe combined


immunodeficiency) (IL2RG)


interleukin 4 receptor (IL4R)
3
X52425
+
+

+

+


interleukin 6 receptor (IL6R)
5
X12830

+



+


interleukin 6 signal transducer
1
M57230


(gp130, oncostatin M


receptor) (IL6ST)


interleukin 7 receptor (IL7R)
14
M29696
+




+


interleukin 7 receptor (IL7R)
1
AF043123


(low match)


interleukin 8 (IL8)
8
Y00787
+

+

+

High in activated T











cells, bone and











pancreatic islets


interleukin 8 receptor alpha
11
L19591


(IL8RA)


interleukin 8 receptor, beta
14
M94582


(IL8RB)


interleukin enhancer binding
3
U10323
+
+
+
+
+
+
high in uterus


factor 2, 45 kD (ILF2)


interleukin enhancer binding
2
U10324


factor 3, 90 kD (ILF3)


interleukin-1 receptor-
2
L76191

+
+
+

+


associated kinase 1 (IRAK1)


interleukin-1 receptor-
1
U52112


associated kinase 1 (low


match)


interleukin-10 receptor, alpha
5
U00672
+
+
+
+


(IL10RA)


interleukin-11 receptor, alpha
7
Z38102

+
+


(IL11RA)


INTERLEUKIN-14
1
P40222


PRECURSOR (IL-14) (HIGH


MOLECULAR WEIGHT B-


CELL GROWTH FACTOR)


(HMW-BCGF) (non-exact


46%)


intestinal carboxylesterase;
1
U60553

+


+


liver carboxylesterase-2 (ICE)


inversin protein (non-exact
1
AF084367


52%)


IQ motif containing GTPase
6
L33075


activating protein 1 (IQGAP1)


IQ motif containing GTPase
1
U51903

+

+


activating protein 2 (IQGAP2)


isocitrate dehydrogenase 1
1
AF020038
+
+
+
+
+
+


(NADP+), soluble (IDH1)


isocitrate dehydrogenase 2
2
X69433
+
+
+
+
+
+


(NADP+), mitochondrial


(IDH2)


isocitrate dehydrogenase 3
2
U07681


+


(NAD+) alpha (IDH3A)


isocitrate dehydrogenase 3
1
Z68907
+
+
+
+

+


(NAD+) gamma (IDH3G)


isolate Aus3 cytochrome b
1
AF042516


(CYTB)


isolate TzCCR5-179 CCR5
1
AF011524


receptor (CCR5)


isopentenyl-diphosphate delta
5
X17025
+
+
+
+

+


isomerase (IDI1)


Janus kinase 1 (a protein
4
M64174
+
+
+
+

+


tyrosine kinase) (JAK1)


Janus kinase 2 (a protein
1
AF005216


tyrosine kinase) (JAK2)


Jk-recombination signal
2
L07876


binding protein (RBPJK)


JM1 protein
1
AJ005890

+

+


jumonji (mouse) homolog
1
U57592

+
+
+

+


(JMJ)


jun D proto-oncogene (JUND)
1
X51346
+
+
+
+

+


jun dimerization protein
1
AF111167






only found in germ


junction plakoglobin (JUP)
1
M23410

+
+
+

+


kangai 1 (suppression of
1
U20770
+
+
+
+
+
+


tumorigenicity 6, prostate;


CD82 antigen (R2 leukocyte


antigen,


antigen detected by


monoclonal and antibody


IA4)) (KAI1)


karyopherin (importin) beta 1
2
L39793
+
+
+
+
+
+


(KPNB1)


karyopherin (importin) beta 2
1
U72395
+
+
+
+


(KPNB2)


karyopherin alpha 1 (importin
1
S75295
+
+
+

+


alpha 5) (KPNA1)


karyopherin alpha 2 (RAG
1
U09559


cohort 1, importin alpha 1)


(DPNA2)


karyopherin alpha 3 (importin
1
D89618

+


+


alpha 4) (KPNA3)


karyopherin alpha 4 (KPNA4)
1
M17887

+
+


Katanin (80 kDa) (KAT)
1
AF052432

+
+
+

+


KE03 protein
2
AF064604


Kelch-like ECH-associated
1
D50922


protein 1 (KIAA0132)


(66% aa)


Keratin 8 (KRT8)
1
X74929

+
+
+
+
+


ketohexokinase (fructokinase)
1
X78678

+

+
+


(KHK)


KIAA0001 (KIAA0001) (72%
1
Q15391


aa)


KIAA0001 (KIAA0001) (76%
1
Q15391


aa)


KIAA0001 (KIAA0001)
1
Q15391


(non-exact 72%)


KIAA0002 (KIAA0002)
5
D13627

+
+
+

+


KIAA0005 (KIAA0005)
4
D13630

+
+
+

+


KIAA0010 (KIAA0010)
1
D13635

+



+


KIAA0016 (KIAA0016)
1
D13641
+
+
+
+

+


KIAA0017 (KIAA0017)
2
D87686


KIAA0022 (KIAA0022)
2
D14664

+
+
+


KIAA0023 (KIAA0023)
1
D14689

+


KIAA0024 (KIAA0024)
1
D14694
+
+
+
+

+


KIAA0025 (KIAA0025)
1
D14695

+
+
+
+
+


KIAA0026 (KIAA0026)
2
D14812

+
+
+

+


KIAA0027
1
D25217

+


KIAA0032 (KIAA0032)
2
D25215

+
+
+


KIAA0040 (KIAA0040)
1
D25539
+
+
+
+

+


KIAA0050 (KIAA0050)
4
D26069


KIAA0053 (KIAA0053)
17
D29642
+

+
+


KIAA0057 (KIAA0057)
1
D31762
+
+
+
+
+
+
high in fetal lung


KIAA0058 (KIAA0058)
11
D31767
+
+
+
+

+


KIAA0063 (KIAA0063)
3
D31884
+
+
+
+

+


KIAA0064 (KIAA0064)
1
D31764
+
+
+
+

+


KIAA0066
1
D31886
+
+
+
+

+


KIAA0068
1
D38549

+
+
+
+
+


KIAA0073
3
D38552

+
+
+

+


KIAA0081
2
D42039

+

+

+


KIAA0084
2
D42043
+
+
+
+

+


KIAA0085
26
U30498
+
+
+
+
+
+


KIAA0088
3
D42041
+
+
+
+
+
+


KIAA0090
2
D42044
+
+
+
+
+
+


KIAA0092 (KIAA0092)
1
D42054

+
+
+

+


KIAA0094
3
D42084


+
+


KIAA0095 (KIAA0095)
1
D42085


KIAA0096
1
D43636
+
+
+
+

+


KIAA0097 (KIAA0097)
1
X92474
T
+
+

+


KIAA0099 (KIAA0099)
3
D43951
+
+
+
+
+
+


KIAA0102 (KIAA0102)
2
D14658

+

+
+
+


KIAA0105
1
D14661
B
+


+
+


KIAA0120
2
P37802


KIAA0120 (non-exact, 65%)
1
M83106


KIAA0121 (KIAA0121)
1
D50911
+
+
+
+

+


KIAA0123
1
D21064

+
+
+

+


KIAA0128
1
D50918
+
+
+
+

+


KIAA0129 (KIAA0129)
1
D50919
+
+
+
+


KIAA0130 (KIAA0130)
1
AF055995

+
+
+


KIAA0136
2
D50926


KIAA0137 (KIAA0137)
1
AB004885

+
+
+

+


KIAA0140 (KIAA0140)
1
D50930
+
+

+

+


KIAA0141 (KIAA0141)
3
D50931


KIAA0144 (KIAA0144)
3
D63478
+
+
+
+

+


KIAA0144 (KIAA0144) (low
1
D63478


match)


KIAA0144 (non-exact 61%)
1
Q14157


KIAA0144 (non-exact 65%)
1
Q14157


KIAA0146
2
D63480

+
+
+

+


KIAA0148 (KIAA0148)
1
D63482

+



+


KIAA0154
2
D63876
+
+
+
+

+


KIAA0156
1
D63879

+
+
+

+


KIAA0160
2
D63881


KIAA0161 (KIAA0161)
1
D79983
+
+

+


KIAA0164 (KIAA0164)
3
D79986


KIAA0167 (KIAA0167)
1
D79989

+


KIAA0168 (KIAA0168)
3
D79990

+
+
+

+


KIAA0169
3
D79991


KIAA0171 (KIAA0171)
3
D79993

+
+
+

+


KIAA0174 (KIAA0174)
7
D79996
+
+
+
+

+


KIAA0179
2
D80001

+
+
+

+


KIAA0181
1
D80003

+
+
+

+


KIAA0183
4
D80005
+
+
+
+
+
+


KIAA0184
1
D80006
+
+
+
+

+


KIAA0191 (72% aa)
1
D83776


KIAA0191 (non-exact 77%)
1


KIAA0193 (KIAA0193)
1
D83777
+
+
+
+

+


KIAA0200 (KIAA0200)
1
D83785

+
+
+

+


KIAA0210 (KIAA0210)
3
D86965


KIAA0217
2
D86971
+
+
+
+

+


KIAA0219
2
U77700

+
+
+

+


KIAA0222 (KIAA0222)
1
D86975


KIAA0223
2
D86976


KIAA0229
1
D86982
+
+


KIAA0232 (KIAA0232)
1
D86985

+
+
+

+


KIAA0233 (KIAA0233)
1
D87071


KIAA0235
2
D87078
+
+
+
+


KIAA0239
1
D87076
+
+


KIAA0239 (non-exact 80%)
1
D87076


KIAA0240
1
D87077


KIAA0242
4
D87684
+
+
+
+
+
+


KIAA0248
2
D87435

+
+
+

+


KIAA0249 (KIAA0249)
3
D87436
+
+
+
+

+


KIAA0253
5
D87442
+
+
+
+
+
+


KIAA0254 (KIAA0254)
1
D87443

+
+
+


KIAA0255(KIAA0255)
4
D87444

+
+
+

+


KIAA0262 (KIAA0262)
3
D87451
+
+
+
+

+


KIAA0263 (KIAA0263)
1
D87452
+
+
+
+

+


KIAA0264
3
D87453

+
+
+

+


KIAA0268
1
D87742
+
+

+

+


KIAA0269
1
Q92558


KIAA0275 (KIAA0275)
13
D87465
+
+

+

+


KIAA0304 (KIAA0304)
2
AB002302
+
+
+
+
+
+


KIAA0308
2
AB002306

+
+


+


KIAA0310 (KIAA0310)
1
AB002308

+
+
+

+


KIAA0314 (=U96635
3
AB002312


M. musculus ubiquitin protein


ligase Nedd-4)


KIAA0315 (KIAA0315)
4
AB002313

+
+
+
+
+


KIAA0325 (=L08505
2
AB002323


R. norvegicus cytoplasmic


dynein heavy chain (MAP1C))


KIAA0329 (KIAA0329)
1
AB002327

+
+
+

+


KIAA0330
1
AB002328
+
+
+


+


KIAA0332
1
AB002330

+
+
+

+


KIAA0333
2
AB002331

+
+
+
+
+


KIAA0336 (KIAA0336)
3
AB002334
+
+
+
+

+


KIAA0336 (KIAA0336) (low
1
AB002334


match)


KIAA0342 (KIAA0342)
1
AB002340

+
+


+


KIAA0344 (KIAA0344)
2
AB002342



+

+


KIAA0354 (KIAA0354)
1
AB002352
+
+
+
+

+


KIAA0365 (KIAA0365)
3
AB002363
+
+
+
+
+
+


KIAA0370
6
AB002368

+
+
+
+
+


KIAA0372 (KIAA0372)
1
AB002370


KIAA0373 (KIAA0373)
1
AB002371

+

+


KIAA0375 (KIAA0375)
1
AB002373

+

+


KIAA0377 (KIAA0377)
1
AB002375

+

+
+


KIAA0379
1
AB002377



+


KIAA0379 (non-exact, 65%)
1
AB002377


KIAA0380 (KIAA0380)
1
AB002378
+
+

+

+


KIAA0380 (KIAA0380)
1
AB002378


(60% aa)


KIAA0382 (KIAA0382)
2
AB002380

+
+
+

+


KIAA0383
1
AB002381


KIAA0386 (KIAA0386)
5
AB002384


KIAA0392
1
AB002390


KIAA0397 (KIAA0397)
4
AB007857

+
+
+
+
+


KIAA0403
3
AB007863


KIAA0404
1
AB007864

+

+


KIAA0409
1
AB007869

+

+


KIAA0421
1
AB007881
+
+
+


+


KIAA0424 (non-exact 82%)
1
AB007884


KIAA0428 (KIAA0428)
9
Y13829


KIAA0429 (KIAA0429)
2
AB007889
+
+
+
+

+


KIAA0430 (KIAA0430)
2
AB007890






only in ovary


KIAA0432 (KIAA0432)
2
U86753
T
+
+


KIAA0435 (KIAA0435)
1
AB007895


KIAA0438 (KIAA0438)
1
AB007898

+
+
+

+


KIAA0447 (KIAA0447)
3
AB007916
+
+
+
+

+


KIAA0449
1
AB007918

+



+


KIAA0456
1
AB007925

+
+
+

+


KIAA0458 (KIAA0458)
1
AB007927


KIAA0462
1
AB007931
+
+
+
+

+


KIAA0465
1
AB007934

+
+
+
+
+


KIAA0476 (KIAA0476)
1
AB007945

+
+
+


KIAA0489
1
AB007958


KIAA0494 (KIAA0494)
1
AB007963
+
+
+
+

+


KIAA0515
1
AB011087
+
+
+
+

+


KIAA0521
3
AB011093
+
+



+


KIAA0525
1
AB011097

+

+


KIAA0530
1
AB011102

+
+
+


KIAA0532
1
AB011104
+
+
+
+

+


KIAA0537 (KIAA0537)
1
AB011109


KIAA0540
1
AB011112
+
+
+
+

+


KIAA0543
1
AB011115


+
+

+


KIAA0544
1
AB011116

+
+
+

+


KIAA0549
2
AB011121

+
+
+

+


KIAA0551
2
AB011123

+



+


KIAA0554
8
AB011126

+
+
+

+


KIAA0561
1
AB011133

+

+


KIAA0562 (KIAA0562)
1
AB011134


KIAA0563 (KIAA0563)
1
AB011135


KIAA0569 (KIAA0569)
2
AB011141

+
+
+

+


KIAA0571 (KIAA0571)
2
AB011143

+
+
+


KIAA0573
1
AB011145

+

+

+


KIAA0576
1
AB011148


KIAA0580
1
AB011152


KIAA0584
1
AB011156

+


KIAA0592
3
AB011164
+
+
+
+

+


KIAA0596
1
AB011168

+
+


KIAA0598 (KIAA0598)
1
AB011170

+
+
+


KIAA0608
1
AB011180


+
+


KIAA0614
2
AB014514
+
+
+
+

+


KIAA0615 (KIAA0615)
1
AB014515


KIAA0621
1
AB014521

+
+


+


KIAA0648
1
AB014548

+
+
+

+


KIAA0652 (KIAA0652)
1
AB014552
+
+
+
+

+


KIAA0668
1
AB014568


KIAA0669
1
AB014569


KIAA0671 (KIAA0671)
1
AB014571


+
+

+


KIAA0675 (KIAA0675)
1
AB014575

+

+
+


KIAA0676
1
AB014576

+
+
+

+


KIAA0677 (KIAA0677)
2
AB014577

+
+
+
+
+


KIAA0678
1
AB014578
+
+
+
+

+


KIAA0679
6
AB014579

+
+
+

+


KIAA0680 (KIAA0680)
1
AB014580


KIAA0692
1
AB014592
+
+
+
+

+


KIAA0697
1
AB014597


KIAA0699
1
AB014599
+
+
+
+

+


KIAA0700
1
AB014600

+
+
+

+


KIAA0737 (KIAA0737)
3
AF014837
+
+
+
+

+


KIAA0748 (KIAA0748)
2
AB018291

+


KIAA0763 (KIAA0763)
2
AB018306
+
+
+
+

+


KIAA0769 (KIAA0769)
2
AB018312

+
+
+

+


KIAA0782
1
AB018325
+
+

+


high in BPH stroma


KIAA0796
1
AB018339

+
+
+

+


KIAA0798 (KIAA0798)
1
AB018341


KIAA0823
1
AB020630


KIAA0854
1
AB020661
+
+
+
+

+


KIAA0856
1
AB020663

+
+
+

+


KIAA0860
1
AB020667

+

+


KIAA0862
1
AF054828

+
+
+


KIAA0871 (non-exact 88%)
1
AB020678


KIAA0873
1
AB020680

+
+
+

+


KIAA0892
1
AB020699
+
+
+
+

+


KIAA0906
1
AB020713
+
+
+
+

+


KIAA0991
1
AB023208.1


killer cell lectin-like receptor
1
U11276


+
+

+


subfamily B, member 1


(KLRB1)


killer cell lectin-like receptor
1
U96846


subfamily C, member 4


(KLRC4)


kinectin 1 (kinesin receptor)
1
D13629


(KTN1)


kinesin family member 5B
2
X65873

+
+
+


(KIF5B)


kinesin-like DNA binding
1
AB017430
+
+
+
+

+


protein


Krueppel-related DNA-
1
M61869


binding protein (TF6) (low


match)


Kruppel related gene (clone
1
M20675


pHKR1RS)


Kruppel-like zinc finger
3
U51869
+
+
+
+
+
+


protein Zf9


Kruppel-like zinc finger
1
U44975

+
+

+
+


protein Zf9 (non-exact 76%)


kruppel-type zinc finger
1
AB011414.1


protein, ZK1


L apoferritin
3
X03742


lactate dehydrogenase A
3
X02152

+
+
+
+
+


(LDHA)


lactate dehydrogenase A
1
X02152


(LDHA) (non-exact, 81%)


lactate dehydrogenase B
6
X13794
+
+
+
+
+
+
high in fetal lung


(LDHB)








fibrablast


lactotransferrin (LTF)
1
U07643
+


+

+
high in bone marrow


laminin binding protein (low
1
D28372


score)


laminin receptor 1 (67 kD);
20
X15005
+
+
+
+
+
+
high in many libraries


Ribosomal protein SA


(LAMR1)


laminin receptor homolog {3′
1
S35960


region}


laminin, gamma 1 (formerly
2
J03202
+
+
+


+


LAMB2) (LAMC1)


latent transforming growth
2
M34057

+
+
+

+


factor beta binding protein 1


(LTBP1)


LAZ3/BCL6
1
Z79581


(=Z79582; D28522/4)


LDLC
2
Z34975
+
+
+
+

+


lecithin-cholesterol
1
M17959


acyltransferase (LCAT) (non-


exact, 66%)


lectin, galactoside-binding,
1
M87842



+


soluble, 2 (galectin 2)


(LGALS2)


lectin, galactoside-binding,
1
L13210
+
+
+
+

+


soluble, 3 binding protein


(galectin 6 binding protein)


(LGALS3BP)


leucine rich repeat (in FLII)
5
AJ223075
+
+
+
+
+
+


interacting protein 1


(LRRFIP1)


leucocyte immunoglobulin-
2
AF072099



+


like receptor-5 (LIR-5)


leucocyte immunoglobulin-
7
AF025530


like receptor-6a (LIR-6)


leucocyte immunoglobulin-
2
U82275

+




only found in CNS


like receptor-7 (LIR-7)


leukemia virus receptor 1
1
L20859
+
+
+
+

+


(GLVR1)


leukocyte adhesion protein
1
M29484


p150,95 alpha subunit


leukocyte antigen, HLA-A2
3
Y13267


leukocyte immunoglobulin-
3
AF025528

+


like receptor (MIR-10)


leukocyte tyrosine kinase
1
X60702
+





found only in blood


(LTK)


leukocyte-associated Ig-like
3
AF013249



+


receptor 1 (LIAR1)


leukotriene A4 hydrolase
6
J03459
+
+
+
+
+
+


(LTA4H)


leupaxin (LDPL)
2
AF062075
+


+

+


ligase I, DNA, ATP-
1
M36067
B, T
+
+

+
+


dependent (LIG1)


LIM and SH3 protein 1
2
X82456
+
+
+
+
+
+


(LASP1)


LIM domain kinase 2
2
AC002073
+
+
+
+

+


(LIMK2)


line-1 protein
1


Line-1 repeat mRNA with 2
1
U93566
+
+
+
+
+
+


open reading frames


Line-1 repeat with 2 open
1
M22332
+
+
+
+
+
+
high in gastric tumor


reading frames


LINE-1 REVERSE
1
P08547


TRANSCRIPTASE


HOMOLOG


lipase A, lysosomal acid,
4
X76488
+
+
+
+

+


cholesterol esterase (Wolman


disease) (LIPA)


lipase, hormone-sensitive
1
L11706
+
+



+


(LIPE)


LMP7
1
L11045


Lon protease-like protein
2
X74215
+
+
+
+

+


(LONP)


low density lipoprotein-
2
AF058414




+

only in liver


related protein 1 (alpha-2-


macroglobulin receptor)


(LRP1)


low density lipoprotein-
1
M63959

+
+

+
+


related protein-associated


protein 1 (alpha-2-


macroglobulin receptor-


associated protein 1)


(LRPAP1)


low density lipoprotein-
1
M63959


related protein-associated


protein 1 (alpha-2-


macroglobulin receptor-


associated protein 1)


(LRPAP1) (non-exact, 75%)


low-affinity Fc-gamma
1
L08107


receptor IIA


LPS-induced TNF-alpha
9
AF010312
+
+
+
+
+
+


factor (PIG7)


Lst-1
1
U00921
+
+
+
+

+


L-type amino acid transporter
1
AF104032


subunit LAT1


lung resistance-related protein
1
X79882
+
+
+
+

+


(LRP)


Lymphocyte antigen 75
1
AF011333
B


(LY75)


lymphocyte antigen 9 (LY9)
2
L42621


lymphocyte antigen HLA-
2
L42345


B*4402 and HLA-B*5101


lymphocyte cytosolic protein
42
J02923


1 (L-plastin) (LCP1)


lymphocyte cytosolic protein
4
U20158
T lymphoma,


2 (SH2 domain-containing


T activated


leukocyte protein of 76 kD)


(LCP2)


lymphocyte glycoprotein
2
X04391
+

+


T1/Leu-1


lymphocyte-specific protein 1
16
M33552
+
+
+
+

+


(LSP1)


lymphocyte-specific protein
7
M36881

+



+


tyrosine kinase (LCK)


lymphoid phosphatase LyP1
1
AF001847


lymphoid-restricted membrane
4
U10485
+

+
+


protein (LRMP)


lymphoid-specific SP100
1
U36500





+


homolog (LYSP100-A)


lymphoma proprotein
2
U33849
+
+
+
+

+


convertase (LPC)


LYSOSOMAL
1
P10619


PROTECTIVE PROTEIN


PRECURSOR (CATHEPSIN


A) (CARBOXYPEPTIDASE


C)


lysosomal-associated
1
J04182
+
+
+
+
+
+


membrane protein 1 (LAMP1)


Lysosomal-associated
1
J04183

+
+
+
+
+


membrane protein 2 (LAMP2)


lysozyme (renal amyloidosis)
39
M19045
+
+
+
+

+


(LYZ)


lysyl-tRNA synthetase
2
D32053
+
+
+
+

+


(KARS)


M phase phosphoprotein 10
1
X98494


(U3 small nucleolar


ribonucleoprotein) (MPP-10)


M1-type and M2-type
2
X56494


pyruvate kinase


m6A methyltransferase (MT-
7
AF014837
+
+

+


A70)


mab-21 (C. elegans)-like 1
1
U38810

+
+
+

+


(MAB21L1)


MacMarcks
1
X70326
+
+
+
+
+
+


macrophage-associated
1
Z22968

+
+
+

+


antigen (MM130)


MADS box transcription
1
U49020

+
+
+

+


enhancer factor 2, polypeptide


A (myocyte enhancer factor


2A) (MEF2A)


MADS box transcription
1
L08895

+
+
+

+


enhancer factor 2, polypeptide


C (myocyte enhancer factor


2C) (MEF2C)


major cytoplasmic tRNA-
1
X17516


Val(IAC) (=M33940)


major histocompatibility
1
M95531


complex class I beta chain


(HLA-B)


major histocompatibility
41
Z93949
+
+
+
+

+
high in villous adenoma


complex, class I, A (HLA-A)


major histocompatibility
1
Z72422


complex, class I, A (HLA-A)


(low match)


major histocompatibility
82
M24097
+
+
+
+
+
+


complex, class I, C (HAL-C)


major histocompatibility
77
M20022
+
+
+
+

+


complex, class I, E (HLA-E)


major histocompatibility
2
U15085
+
+
+
+

+


complex, class II, DM BETA


(HLA-DMB)


major histocompatibility
10
M57466
+
+
+
+

+


complex, class II, DP beta 1


(HLA-DPB1)


major histocompatibility
9
V00522
+
+
+
+

+


complex, class II, DR beta 1


(HLA-DRB1)


Major histocompatibility
2
M24070

+
+

+
+


complex, class II, Y box-


binding protein I; DNA-


binding protein B (YB1)


malate dehydrogenase 1, NAD
1
D55654
+
+
+
+
+
+


(soluble) (mdh1)


malate dehydrogenase 1, NAD
3
D55654

+
+

+
+


(soluble) (MDH1)


malonyl-CoA decarboxylase
2
AF097832


precursor


maltase-glucoamylase (mg)
1
AF016833



+


manic fringe (Drosophila)
1
U94352
+
+
+
+

+


homolog (MFNG)


mannose phosphate isomerase
1
X76057

+
+
+

+


(MPI)


mannose phosphate isomerase
2
X76057

+
+
+

+


(mpi)


mannose-6-phosphate receptor
3
X56253

+
+

+
+


(cation dependent) (M6PR)


mannose-P-dolichol
1
AF038961

+
+
+

+


utilitzation defect 1 (MPDU1)


mannosidase, alpha B,
1
U60885

+

+
+
+


lysosomal (MANB)


mannosyl (alpha-1,3-)-
1
M55621
+
+
+
+
+
+


glycoprotein beta-1,2-N-


acetylglucosaminyltransferase


(MGAT1)


map 4q35 repeat region
1
AF064849


MAP kinase-interacting
2
AB000409

+
+
+
+
+


serine/threonine kinase 1


(MKNK1)


MAP/ERK kinase kinase 3
5
U78876

+


(MEKK3)


MAP/ERK kinase kinase 5
1
D84476

+
+

+


(MEKK5)


MAP/microtubule affinity-
4
M80359

+
+


+


regulating kinase 3 (MARK3)


Marenostrin protein
1
Y14441


MASL1
1
AB016816


MAX dimerization protein
3
L06895





+


(MAD)


MaxiK potassium channel
1
AF035046


beta subunit


MBP-2 for MHC binding
1
X65644

+
+
+

+


protein 2


Meis (mouse) homolog 3
1
U68385

+
+
+

+


(MEIS3)


melanoma-associated antigen
1
M12154


p97 (melanotransferrin)


membrane cofactor protein
4
X59405

+
+
+

+


(CD46, trophoblast-


lymphocyte cross-reactive


antigen) (MCP)


membrane component,
4
D14696

+
+
+
+
+


chromosome 17, surface


marker 2 (ovarian carcinoma


antigen CA125) (M17S2)


membrane metallo-
2
J03779
B

+
+
+
+


endopeptidase (neutral


endopeptidase, enkephalinase,


CALLA, CD10) (MME)


membrane protein,
2
M64925

+
+
+
+
+


palmitoylated 1 (55 kD)


(MPP1)


meningioma expressed
1
U94780



+


antigen (MGEA)


meningioma-expressed
1
U73682
+
+

+
+


antigen 11 (MEA11)


Menkes Disease (ATP7A)
1
L06133

+


putative Cu++-transporting P-


type ATPase


metallothionein 2A (MT2A)
1
V00594

+
+
+
+
+


metaxin 1 (MTX1)
1
U46920

+

+

+


methionine
2
X68836
+
+
+
+

+


adenosyltransferase II, alpha


(MAT2A)


methyl-CpG binding domain
1
Y10746


protein 1 (MBD1) (non-exact


59% aa)


methylene tetrahydrofolate
2
X16396
+
+
+
+

+


dehydrogenase (NAD+


dependent),


methenyltetrahydrofolate


cyclohydrolase (MTHFD2)


methylenetetrahydrofolate
1
J04031

+
+
+
+
+


dehydrogenase (NADP+


dependent),


methenyltetrahydrofolate


cyclohydrolase,


formyltetrahydrofolate


synthetase (MTHFD1)


methyltransferase, putative
2
AJ224442


MHC antigen (HLA-B)
1
U14943


(=L42024)


MHC class 1 region
2
AF055066


MHC class I antigen (HLA-
1
U70863


A2)


MHC class I antigen (HLA-
1
U19736


A33)


MHC class I antigen (HLA-C)
1
U38975


MHC class I antigen B*5801
1
U52813


(HLA-B)


MHC class I antigen HLA-A
2
AF015930


(HLA-A)


MHC class I antigen HLA-A
1
U36687


(HLA-A-2402 allele)


MHC class I antigen HLA-
2
X13112


A11K


MHC class I antigen HLA-B
1
U67331


(B*0801 variant)


(=AF028596)


MHC class I antigen HLA-B
1
U67330


(B*0801 variant) (=U88254)


MHC class I antigen HLA-B
1
AF017328


(B*48 allele)


MHC class I antigen HLA-B
1
AF014770


(HLA-B*1502 allele)


MHC class I antigen HLA-B
1
U58643


(HLA-B*40MD)


MHC class I antigen HLA-B
1
AF028596


(HLA-B*4103 allele)


MHC class I antigen HLA-B
1
AF035648


gene (HLA-B*4402 variant


allele)


MHC class I antigen HLA-B
1
U52175


GN00110-B*3910


MHC class I antigen HLA-
1
D83030


Cw*04011


MHC class I antigen R69772
1
U56434


HLA-A (A*0302)


MHC class I antigen SHCHA
1
U58469


(HLA-B*4403 variant)


MHC class I
1
U06697


histocompatibility antigen


(HLA-B) (clone C21/14)


MHC class I HLA B71
2
L07950


MHC class I HLA-A
1
Flp


(Aw33.1)


MHC class I HLA-B
1
U18660


MHC class I HLA-B (HLA-B-
1
U18661


07ZEL allele) (=X86704)


MHC class I HLA-B (HLA-B-
1
U28759


08NR allele)


MHC class I HLA-B*3512
1
L76094


MHC class I HLA-B41
3
U17572


variant (=U17572)


MHC class I HLA-B44.2
1
M24038


chain


MHC class I HLA-B51-cd3.3
1
L41086


MHC class I HLA-C allele
2
Z33459


MHC class I HLA-Cw*0304
1
D64150


(=M84172; M99389)


MHC class I HLA-Cw*0803
3
Z15144


MHC class I HLA-Cw6
1
M28206


MHC class I HLA-J antigen
1
L56139


MHC class I lymphocyte
1
M19670


antigen A2 (A2.1) variant


DK1


MHC class I mic-B antigen
1
X91625


MHC class I polypeptide-
1
L14848



+


related sequence A (MICA)


MHC class I protein HLA-C
1
U61274


heavy chain (C*0701new


allele) (=AF017331)


MHC class II DNA Sequence
1
L18885


(clone A37G7-1C11)


MHC class II DQ-alpha
1
M16995
+

+
+

+


associated with DRw6, DQw1


protein


MHC class II DQ-beta
2
M17564

+

+

+


associated with DR2, DQw1


protein


MHC class II HAL-DQ-LTR5
1
M33842


(DQ, w8) DNA fragment, long


terminal repeat region


MHC class II hla-dr alpha-
1
J00195


chain


(=J00197; M60334; K011171; J00194;


M60333; X00274)


MHC class II HLA-DRB1
1
AF007883


MHC class II HLA-DRw11-
1
M21966


beta-I chain (DRw11.3)


MHC class II lymphocyte
1
M23907


antigen (DPw4-beta-1)


MHC CLASS II
1
P33076


TRANSACTIVATOR CIITA


(non-exact 57%)


MHC HLA-E2.1 (=X87679)
1
M32507


MHC HLA-E2.1 (alpha-2
1
M32507


domain) (low match)


Mi-2 autoantigen 240 kDa
1
U08379


protein (non-exact 84%)


microsomal stress 70 protein
1
U04735


ATPase core (stch)


microtubule-associated
1
U19727
+
+
+
+

+


protein 4 (MAP4)


microtubule-associated
1
X73882


protein 7 (MAP7)


mineralocorticoid receptor
2
M16801

+

+

+


(aldosterone receptor) (MLR)


minichromosome maintenance
1
X62153

+
+
+

+


deficient (S. cerevisiae) 3


(MCM31)


minichromosome maintenance
1
AB011144

+
+
+

+


deficient (S. cerevisiae) 3-


associated protein


(MCM3AP)


minichromosome maintenance
2
X74795
+
+
+
+
+
+


deficient (S. cerevisiae) 5 (cell


division cycle 46) (MCM5)


mitochondiral cytochrome b
1
AF042517


(CYTB)


mitochondrial 16S rRNA
11
Z70759


mitochondrial ATP synthase
2
X59066


(F1-ATPase) alpha subunit


mitochondrial ATP synthase c
1
X69907


subunit (P1 form)


mitochondrial cytochrome b
6
AF042508


(CYTB)


mitochondrial cytochrome b
1
AB006202


small subunit of complex II


mitochondrial
1
P00395


CYTOCHROME C


OXIDASE POLYPEPTIDE I


mitochondrial
1
P00403


CYTOCHROME C


OXIDASE POLYPEPTIDE II


mitochondrial cytochrome C
2
P00403


oxidase subunit II


mitochondrial cytochrome
5
U12691


oxidase subunit II (COII)


(=U12692 Hsa4


mitochondrion cytochrome


oxidase subunit II)


mitochondrial DNA loop
1
X89763


attachment sequences (clone


LAS34)


mitochondrial DNA
1
U94703

+


polymerase accessory subunit


precursor (MtPolB) nuclear


gene encoding mitochondrial


protein,


mitochondrial DNA, complete
1
X93334


genome


mitochondrial genes for
8
V00710


several tRNAs (Phe, Val, Leu)


and 12S and 16S ribosomal


RNAs.


mitochondrial genes for tRNA
3
V00660


(Phe) and 12S rRNA


(fragment)


mitochondrial inner
1
AF106622


membrane preprotein


translocase Tim17a


mitochondrial isolate Afr7
1
AF042503


cytochrome b(CYTB)


mitochondrial loop attachment
1
X89843


sequence (clone LAS88)


mitochondrial NADH
14
AF014893


dehydrogenase subunit 2


(ND2)


mitochondrial translational
1
L34600

+
+
+

+


initiation factor 2 (MTIF2)


mitochondrion cytochrome b
1
U09500


mitogen inducible gene mig-2
1
Z24725

+
+
+

+


mitogen inducible gene mig-2
1
Z24725


(non-exact, 71%)


mitogen-activated protein
2
U43784

+
+
+

+


kinase-activated protein


kinase 3 (MAPKAPK3)


MLN51
2
X80199

+
+
+
+
+


MLN64 (=D38255 CAB1)
1
X80198
+
+
+
+


moesin (MSN)
14
M69066
+
+
+
+

+


monocytic leukaemia zinc
2
U47742

+
+
+

+


finger protein (MOZ)


MOP1 ( )
2
U29165


motor protein (Hs.78504)
2
D21094
+
+
+
+

+


mouse double minute 2,
1
U39736


+
+


human homolog of; p53-


binding protein (MDM2)


M-phase phosphoprotein 6
1
X98263

+
+
+

+


(MPP-6)


M-phase phosphoprotein,
1
X98260


mpp11


MPS1
1
L20314


Mr 110,000 antigen
2
D64154

+

+
+
+


MRC OX-2, V-like region
1
X05324


(=M17227)


mu-adaptin-related protein-2;
1
Y08387


mu subunit of AP-4 (MU-


ARP2)


multifunctional polypeptide
1
X53793
+
+
+
+

+


similar to SAICAR synthetase


and AIR carboxylase


(ADE2H1)


murine leukemia viral (bmi-1)
1
L13689

+

+

+


oncogene homolog (BMI1)


mutant (Daudi) beta2 -
44
X07621


microglobulin


mutated in colorectal cancers
1
M62397

+
+


+


(MCC)


myeloid cell leukemia
9
L08246
+
+
+
+
+
+


sequence 1 (BCL2-related)


(MCL1)


myeloid cell nuclear
11
M81750
+




+


differentiation antigeN


(MNDA)


myeloid differentiation
4
U70451

+
+
+

+


primary response gene (88)


(MYD88)


myeloid leukemia factor 2
3
U57342

+

+

+


(MLF2)


myeloid/lymphoid or mixed-
8
U89867

+
+
+

+


lineage leukemia (trithorax


(Drosophila) homolog);


translocated to, 7 (MLLT7)


MYH9 (cellular myosin heavy
1
M81105


chain)


myomesin (M-protein) 2
1
X69089


(165 kD) (MYOM2)


myosin IE (MYO1E)
11
X98411

+

+


myosin light chain kinase
1
U48959
+

+
+

+


(MLCK)


myosin phosphatase, target
2
D87930

+
+
+

+


subunit 1 (MYPT1)


myosin regulatory light chain
2
D50372


(=U26162)


myosin VIIa (low match 71)
1
U55208


myosin, heavy polypeptide 9,
3
M81105
+
+
+
+

+


non-muscle (MYH9)


myosin, light polypeptide,
6
X54304
+
+
+
+
+
+


regulatory, non-sarcomeric


(20 kD) (MLCB)


myosin-I beta
1
X98507
+
+
+
+

+


myristoylated alanine-rich
1
D10522

+
+


protein kinase C substrate


(MARCKS, 80K-L) (MACS)


myxovirus (influenza)
1
M30817
+
+
+
+

+


resistance 1, homolog of


murine (interferon-inducible


protein p78) (MX1)


myxovirus (influenza)
3
M30818


+


resistance 2, homolog of


murine (MX2)


N-acetylgalactosaminidase,
2
M62783

+
+

+
+


alpha-(NAGA)


N-acetylglucosamine receptor
1
L03532

+
+
+

+


1 (thyroid) (NAGR1)


NACP/alpha-synuclein
2
U46896


N-acylaminoacyl-peptide
1
D38441

+
+

+
+


hydrolase (APEH)


N-acylsphingosine
11
U47674
+
+
+
+

+


amidohydrolase (acid


ceramidase) (ASAH)


NAD+-specific isocitrate
1
U49283
+
+
+
+
+
+


dehydrogenase beta subunit


precursor (encoding


mitochondrial protein)


NADH dehydrogenase
1
U53468.1
+
+
+
+
+
+


(ubiquinone) 1 alpha


subcomplex, 5 (13 kD, B13)


(NDUFA5)


NADH dehydrogenase
1
AF047181

+
+
+
+
+


(ubiquinone) 1 beta


subcomplex, 5 (16 kD, SGDH)


(NDUFB5)


NADH dehydrogenase
1
AF050640

+
+
+
+
+


(ubiquinone) Fe—S protein 2


(49 kD) (NADH-coenzyme Q


eductase) (NDUFS2)


NADH dehydrogenase
1
M22538


+
+
+
+


(ubiquinone) flavoprotein 2


(24 kD) (NDUFV2)


NADH: ubiquinone
2
AF053070
+
+
+
+
+
+


dehydrogenase 51 kDa


subunit (NDUFV1)


NADH-CYTOCHROME B5
1
P00387


REDUCTASE (B5R) (50% aa)


NADH-UBIQUINONE
1
P03886


OXIDOREDUCTASE


CHAIN 1


Nardilysin (N-arginine dibasic
2
U64898
+
+
+
+

+


convertase) (NRD1)


nascent-polypeptide-
5
X80909

+
+

+
+


associated complex alpha


polypeptide (NACA)


natural killer cell group 7
8
S69115



+

+


sequence (NKG7)


natural killer cell transcript 4
19
M32011
+


(NK4)


natural killer-associated
1
U30274
+





blood only


transcript 3 (NKAT3)


natural killer-associated
1
AF022045
+





blood only


transcript 5 (NKAT5)


natural killer-tumor
1
L04288
B

+

+
+


recognition sequence (NKTR)


N-deacetylase/N-
2
AF042084
+
+

+

+


sulfotransferase (heparan


glucosaminyl) 2 (NDST2)


Ndr protein kinase
3
Z35102

+


Nedd-4-like ubiquitin-protein
1
U96113


ligase WWP1


nel (chicken)-like 2 (NELL2)
3
D83018

+
+


N-ethylmaleimide-sensitive
1
U39412

+


+


factor attachment protein,


alpha (NAPA)


N-ethylmaleimide-sensitive
1
U78107

+
+
+


factor attachment protein,


gamma (NAPG)


neural precursor cell
3
X92544
+
+
+
+

+
high in testis


expressed, developmentally


down-regulated 5 (NEDD5)


neural precursor cell
1
D23662
+
+
+
+
+
+


expressed, developmentally


down-regulated 8 (NEDD8)


neuregulin 1 (NRG1)
1
U02330

+

+
+


neuroblastoma RAS viral (v-
4
AB020692
+
+
+
+

+


ras) oncogene homolog


(NRAS)


Neuroblastoma RAS viral (v-
1
X68286


ras) oncogene homolog


(NRAS) (low match)


Neurofibromin 2 (bilateral
1
S73853

+



+


acoustic neuroma) (NF2)


neuronal apoptosis inhibitory
2
U19251
+
+
+


+


protein (NAIP)


neuronal cell adhesion
1
AB002341

+
+
+

+


molecule (NRCAM)


neuropathy target esterase
1
AJ004832

+
+
+

+


(NTE)


neuropeptide Y3 receptor,
1
D28433


5′UTR (low score)


neurotrophic tyrosine kinase,
14
X03541
+
+
+
+
+
+


receptor, type 1 (NTRK1)


neutrophil cytosolic factor 4
2
U50720


(40 kD)


NG31
1
AF129756


NGAL (=X83006)
1
X99133


nibrin (NBS)
1
AF051334


NIK
1
AB014587

+
+
+

+


Ninjurin 1; nerve injury-
1
U72661

+
+
+

+


induced protein-1


nitrilase 1 (NIT1)
1
AF069987


(=AF069984)


NKG2-D (low match) (non-
1
X54870


exact, 58%)


Nmi
1
U32849


N-myristoyltransferase 1
1
AF043324

+
+
+
+
+


(NMT1)


No arches-like (zebrafish)
1
U79569

+
+
+

+


zinc finger protein (NAR)


non-histone chromosome
1
D50420
+
+
+
+
+
+


protein 2 (S. cerevisiae)-like 1


(NHP2L1)


non-muscle (fibroblast)
1


tropomyosin


non-muscle alpha-actinin
1
U48734


non-muscle myosin alkali
3
M22918
+
+
+
+
+
+
High in fetal adrenal


light chain (Hs.77385)








gland and BPH stroma


non-neuronal enolase (EC
1
X16289


4.2.1.11)


non-receptor tyrosine
1
M33689


phosphatase 1


normal keratinocyte
3
X53778
+
+
+
+
+
+
high in many libraries


substraction library mRNA,


clone H22a


notch group protein (N)
3
M99437


novel protein
1
X99961


novel T-cell activation protein
1
X94232

+
+
+

+


N-ras protein NRU
1
A60196


N-sulfoglucosamine
1
U60111

+



+


sulfohydrolase (sulfamidase)


(SGSH)


nsulin induced gene 1
1
U96876
+
+
+
+
+
+


(INSIG1)


ntegrin, alpha 4 (antigen
3
L12002
+


+


CD49D, alpha 4 subunit of


VLA-4 receptor) (ITGA14)


nterferon, gamma-inducible
1
M63838
+
+
+
+

+


protein 16 (IFI16)


nterleukin 1, beta (IL1RB)
1
M15330


nuclear antigen H731-like
2
U83908

+
+
+

+


protein


nuclear antigen Sp100
4
U36501
+


+
+
+


(SP100)


Nuclear antigen Sp100
1
P23497


(SP100) (85% aa)


Nuclear antigen Sp100
1
P23497


(SP100) (89% aa)


nuclear autoantigenic sperm
1
M97856
+

+


protein (histone-binding)


(NASP)


nuclear corepressor KAP-1
1
U78773


(KAP-1) (=U95040; X97548


TIF1beta zinc finger protein)


Nuclear domain 10 protein
4
U22897
+
+
+
+
+
+


(NDP52)


Nuclear factor (erythroid-
1
S74017

+
+
+
+
+


derived 2)-like 2 (NFE2L2)


Nuclear factor of kappa light
2
M58603

+
+

+
+


polypeptide gene enhancer in


B-cells 1 (p105) (NFKB1)


nuclear factor of kappa light
3
M69043

+
+
+

+


polypeptide gene enhancer in


B-cells inhibitor, alpha


(NFKBIA)


nuclear factor related to kappa
1
U08191

+
+
+

+


B binding protein (NFRKB)


nuclear mitotic apparatus
3
Z11583
+
+
+
+
+
+


protein 1 (NUMA1)


nuclear receptor coactivator 2
1
X97674


(GRIP1)


nuclear receptor coactivator 3
2
AF010227
+
+
+


+


(AIB3)


nuclear receptor coactivator 4
22
X77548

+
+
+
+
+


(ELE1)


nuclear receptor interacting
1
X84373

+

+

+


protein 1 (NRIP1)


nuclear respiratory factor 1
1
U02683
B
+
+


(NRF1)


nuclear RNA helicase, DECD
4
U90426
+
+
+
+

+


variant of DEAD box family


(DDXL)


nuclear transcription factor Y,
1
X59711
B


alpha (NFYA)


nuclear transcription factor,
3
U15306

+
+

+


X-box binding 1 (NFX1)


nuclear transport factor 2
1
X07315
+
+
+
+

+


(placental protein 15) (PP15)


nucleobindin (=M96824)
1
U31336


nucleobindin 1 (NUCB1)
2
M96824
+
+
+
+

+


nucleolar phosphoprotein
1
Z34289

+
+


p130 (P130)


nucleolar protein (KKE/D
1
Y12065
+
+
+
+

+


repeat) (NOP56)


nucleolar protein (MSP58)
1
AF015308


nucleolar protein 1 (120 kD)
1
M32110
+
+


(NOL1)


nucleolar protein p40
1
U86602
+
+
+
+

+


nucleolin (NCL)
2
M60858
+
+
+
+

+


nucleophosmin (nucleolar
14
M28699
+
+
+
+

+


phosphoprotein B23,


numatrin) (NPM1)


nucleophosmin-retinoic acid
1
U41742


receptor alpha fusion protein


NPM-RAR long form


nucleoporin (NUP358)
2
L41840


(=D42063 RanBP2 (Ran-


binding protein 2))


nucleoporin 153 kD (NUP153)
1
Z25535


nucleoporin 98 kD (NUP98)
1
U41815


nucleosome assembly protein
1
D28430


nucleosome assembly protein
1
M86667

+
+
+

+


1-like 1 (NAP1L1)


nucleosome assembly protein
2
U77456
+
+
+
+

+


1-like 4 (NAP1L4)


nucleosome assembly protein,
1
D28430


5′UTR


olfactory receptor (OR7-141)
1
U86281


OLFACTORY RECEPTOR-
1
P34982


LIKE PROTEIN HGMP07E


(OR17-4) (non-exact 65%)


oligodendrocyte myelin
7
L05367

+


glycoprotein (OMG)


O-linked N-acetylglucosamine
1
U77413
+
+

+
+
+


(GlcNAc) transferase (UDP-


N-


acetylglucosamine: polypeptide-


N-acetylglucosaminyl


transferase) (OGT)


oncofetal trophoblast
1
A53531


glycoprotein 5T4 precursor


(non-exact 55%)


Oncogene TIM (TIM) (non-
1
U02082


exact 84%)


ORF (Hs.77868)
1
M68864
+
+
+
+
+
+


ORF1; MER37; putative
1
U49973


transposase similar to pogo


element Length = 454


origin recognition complex,
2
U27459



+


subunit 2 (yeast homolog)-like


(ORC2L)


origin recognition complex,
1
AF022108


subunit 4 (yeast homolog)-like


(ORC4L) (low match)


ornithine aminotransferase
2
M23204

+
+
+


(gyrate atrophy) (OAT)


ornithine decarboxylase
1
M20372


(ODC)


ornithine decarboxylase
11
D78361
+
+
+
+
+
+
High in pancreas, and


antizyme, ORF 1 and ORF 2








activated T cells


orphan receptor (Hs.100221)
2
U07132
+
+
+
+

+


OS-9 precurosor
6
AB002806
+
+
+
+
+
+


osteonectin (=X82259 BM-
1
D28381


40)


ovel centrosomal protein
1
AB008515

+
+
+

+


RanBPM (RANBPM)


over-expressed breast tumor
1
L34839


protein


oviductal glycoprotein 1,
1
U09550


+
+
+


120 kD (OVGP1)


oxidase (cytochrome c)
1
X80695

+
+
+
+
+


assembly 1-like (OXAIL)


oxoglutarate dehydrogenase
4
D10523
T
+
+

+
+


(lipoamide) (OGDH)


oxysterol binding protein
1
M86917
+
+


+


(OSBP)


OZF
1
X70394

+
+
+

+


OZF (non-exact zinc finger)
1
X70394


p21/Cdc42/Rac1-activated
2
U51120
+
+

+


kinase 1 (yeast Ste20-related)


(PAK1)


P35-related protein (=S80990
1
D63392


ficolin)


p40
1
U93569


p40phox (=U50720)
1
X77094


P47 LBC oncogene
4
U03634


p53-induced protein (PIG11)
1
AF010315
+
+
+
+


p54nrb (low match)
1
Y11287


p62 nucleoporin
1
X58521


p63 mRNA for
1
X69910
+
+
+
+

+


transmembrane protein


PAC clone DJ0701O16 from
1
Q07108


7q33-q36 (non-exact 54%)


palmitoyl-protein thioesterase
10
U44772

+
+
+

+


(ceroid-lipofuscinosis,


neuronal 1, infantile; Haltia-


Santavuori disease) (PPT)


papillary renal cell carcinoma
1
X99720
+
+
+
+
+
+


(translocation-associated)


(PRCC)


PAR protein
1
AF115850

+

+


partial EST (clone c-1gh04)
1
Z43627


PAX3/forkhead transcription
1
U02368


factor gene fusion


paxillin (PXN)
4
D86862

+
+
+

+


PBK1 protein
2
AJ007398
+
+
+
+

+


PBS-EST (nz92e01.s1
1
AA732534


NCI_CGAP_GCB1 clone


IMAGE: 1302936) (low score)


PDZ domain protein
1
AJ224747
+


+

+


(Drosophila inaD-like)


(INALD)


PEBP2aC Runt domain
1
Z38108


encoding gene (=Z35728)


peptidase D (PEPD)
1
J04605


peptidylprolyl isomerase A
3
Y00052

+
+
+
+
+
high in many libraries


(cyclophilin A) (PPIA)


peptidylprolyl isomerase D
2
L11667
T
+
+

+
+


(cyclophilin D) (PPID)


peptidylprolyl isomerase E
1
AF042386

+
+

+
+


(cyclophilin E) (PPIE)


PERB11.1 (=U56942 MHC
1
U69630


class I chain-related protein


A)


perforin 1 (preforming
14
M28393


protein) (PRF1)


peroxisomal acyl-CoA
2
X86032


thioesterase (PTE1)


Peroxisomal acyl-coenzyme A
1
X71440

+
+
+
+
+


oxidase


peroxisomal farnesylated
1
X75535

+
+
+
+
+


protein (PXF)


phorbol-12-myristate-13-
1
D90070
B, W


acetate-induced protein


(PMAIP1)


phosphate carrier
1
X77337


(mitochondrial gene?)


Phosphate carrier,
3
X60036
+
+
+
+

+


mitochondrial (PHC)


phosphate cytidylyltransferase
1
L28957
T

+

+


1, choline, alpha isoform


(PCYT1A)


PHOSPHATIDATE
1
Q92903


CYTIDYLYLTRANSFERASE


(CDP-DIGLYCERIDE)


phosphatidylinositol 3-kinase
2
U57843


delta catalytic subunit


phosphatidylinositol 4-kinase,
3
AB005910
+
+
+
+

+


catalytic, beta polypeptide


(PIK4CB)


phosphatidylinositol glycan,
1
L19783

+
+
+
+
+


class H (PIGH)


phosphatidylinositol transfer
2
D30037


protein (PI-TPbeta)


phosphatidylinositol transfer
2
X98654
B, T
+


protein, membrane-associated


lymphoma


(PITPNM)


phosphatidylinositol transfer
1
X98654


protein, membrane-associated


(PITPNM) (non-exact 64%)


phosphatidylinositol-4-
1
U14957


+

+


phosphate 5-kinase, type II,


alpha (PIP5K2A)


phosphatidylinositol-4-
1
U85245

+
+
+

+


phosphate 5-kinase, type II,


beta (PIP5K2B)


phosphodiesterase 7A
1
L12052
B, W
+
+

+


(PDE7A)


phosphodiesterase IB
1
U56976

ONLY


(PDES1B)


phosphoglucomutase 1
2
M83088

+
+
+

+


(PGM1)


phosphogluconate
1
U30255


+


dehydrogenase (PGD)


phosphoglycerate kinase 1
12
V00572


(PGK1)


phosphoglycerate mutase 1
3
J04173
+
+
+
+
+
+


(brain) (PGAM1)


phosphoglycerate mutase 2
1
M55673

+
+


+


(muscle) (PGAM2)


phosphoinositide-3-kinase,
1
Z29090

+
+
+


catalytic, alpha polypeptide


(PIK3CA)


phosphoinositide-3-kinase,
4
U86453

+
+
+

+


catalytic, delta polypeptide


(PIK3CD)


phosphoinositide-3-kinase,
1
X83368


catalytic, gamma polypeptide


(PIK3CG)


phospholipase C
1
X14034


phospholipase C, delta 1
2
U09117

+
+
+

+


(PLCD1)


phospholipase C, gamma 1
1
M34667
+
+
+
+

+


(formerly subtype 148)


(PLCG1)


phospholipid scramblase
1
AF008445


phosphoribosyl
1
D61391

+
+


+


pyrophosphate synthetase-


associated protein 1


(PRPSAP1)


phosphoribosylglycinamide
3
X54199

+
+
+
+
+


formyltransferase,


phosphoribosylglycinamide


synthetase,


phosphoribosylaminoimidazole


synthetase (GART)


phosphorylase kinase, alpha 2
3
D38616

+
+
+
+
+


(liver), glycogen storage


disease IX (PHKA2)


phosphorylase, glycogen;
1
U47025
+
+
+


+


brain (PYGB)


phosphorylase, glycogen;
1
U47025


brain (PYGB) (low match,


non-exact, 75%)


phosphorylase, glycogen; liver
1
Y15233

+
+
+

+


(Hers disease, lycogen storage


disease type VI) (PYGL)


phosphorylation regulatory
2


protein HP-10


phosphotidylinositol transfer
1
D30036
+
+
+
+

+


protein (PITPN)


pigment epithelium-derived
1
U29953
+
+
+
+
+
+


factor (PEDF)


pim-1 oncogene (PIM1)
1
M24779
+
+
+


+


pinin, desmosome associated
1
U77718
B, monocyte,


protein (PNN)


T lymphoma


placenta (Diff33)
5
U49188

+
+
+

+


placenta (Diff33) (non-exact,
1
U49188


69%)


placenta (Diff48)
18
U49187
+


placenta (Diff48) (low match)
1
U49187


placenta(Diff48) (low match)
1
U49187


plasminogen activator,
1
X74039

+

+

+


urokinase receptor (PLAUR)


platelet factor 4 (PF4)
1
M25897


+


+


platelet/endothelial cell
8
M37780

+
+
+
+
+


adhesion molecule (CD31


ntigen) (PECAM1)


platelet-activating factor
4
U89386

+
+
+


acetylhydrolase 2 (40 kD)


(PAFAH2)


platelet-activating factor
1
U72342
+
+
+
+
+
+


acetylhydrolase, isoform Ib,


alpha subunit (45 kD)


(PAFAH1B1)


platelet-activating factor
1
D10202

+



+


receptor (PTAFR)


pleckstrin (PLEK)
10
X07743


+
+

+


pleckstrin (PLEK) (low
1
X07743


match)


pleckstrin homology, Sec7
4
M85169
+
+

+

+


and coiled/coil domains


1(cytohesin 1) (PSCD1)


pleckstrin homology, Sec7
4
L06633
+


+


and coiled/coil domains,


binding protein (PSCDBP)


pM5 protein
1
X57398
+
+
+
+

+


PMP69
2
Y14322


poly (ADP-ribose) polymerase
1
X56140


(NAD (+) ADP-


ribosyltransferase) (=X16674)


poly(A) polymerase (PAP)
1
X76770
+
+
+
+

+


poly(A)-binding protein-like 1
19
Y00345
+
+
+
+
+
+


(PABPL1)


poly(rC)-binding protein 1
3
X78137
+
+
+
+
+
+


(PCBP1)


polyadenylate binding protein
1
U75686


polycystic kidney disease 1
5
U24498


(autosomal dominant) (PKD1)


polymerase (DNA directed),
1
D29013

+


+
+


beta (POLB)


polymerase (DNA directed),
6
D84103


gamma (POLG)


polymerase (RNA) II (DNA
1
X63564
+
+
+
+
+
+


directed) polypeptide A


(220 kD) (POLR2A)


polymyositis/scleroderma
1
L01457
+
+
+
+
+
+


autoantigen 2 (100 kD)


(PMSCL2)


polypyrimidine tract binding
1
X65372
+
+
+
+
+
+


protein (heterogeneous


nuclear ribonucleoprotein I)


(PTB)


positive regulator of
3
U13021


+


programmed cell death ICH-


1L (Ich-1)


postmeiotic segregation
1
M16514
+
+
+
+

+


increased 2-like 12


(PMS2L12)


postmeiotic segregation
1
U38964
+
+
+
+

+


increased 2-like 8 (PMS2L8)


potassium inwardly-rectifying
1
D87291



+

+


channel, subfamily J, member


15 (KCNJ15)


potassium voltage-gated
1
AF051426

+
+
+

+


channel, KQT-like subfamily,


member 1 (KCNQ1)


POU domain, class 2,
1
Z49194



+


associating factor 1


(POU2AF1)


POU domain, class 2,
2
X13403

+

+


transcription factor 1


(POU2F1)


PPAR binding protein
1
Y13467
+
+
+
+

+


(PPARBP)


PPAR gamma2
1
D83233


pre-B-cell colony-enhancing
8
U02020


factor (PBEF)


prefoldin 1 (PFDN1)
1
Y17392
+
+
+
+
+
+


prefoldin 5 (PRFLD5)
3
D89667
B
+
+

+


prefoldin subunit 3 (=U96759
1
Y17394


von Hippel-Lindau binding


protein (VBP-1))


pregnancy-associated plasma
1
U28727

+

+


high in placenta


protein A (PAPPA)


pre-mRNA splicing factor
1
U08815
+
+
+
+

+


SF3a (60 kD), similar to S. cerevisiae


PRP9


(spliceosome-associated


protein 61) (SF3A60)


pre-mRNA splicing factor
1
U08815


SF3a (60 kD), similar to S. cerevisiae


PRP9


(spliceosome-associated


protein 61) (SF3A60) (low


score)


pre-mRNA splicing factor
2
D28423


SRp20, 5′UTR


preprotein translocase
3
X97544
+
+
+
+

+


(TIM17)


prion protein
1
X82545


prion protein (p27-30)
1
M13899

+
+
+

+


(Creutzfeld-Jakob disease,


Gerstmann-Strausler-


Scheinker syndrome, fatal


familial insomnia) (PRNP)


pristanoyl-CoA oxidase (low
1
Y11411


match)


pristanoyl-CoA oxidase (low
1
Y11411


score)


procollagen-lysine, 2-
1
M98252

+
+
+

+


oxoglutarate 5-dioxygenase


(lysine hydroxylase, Ehlers-


Danlos syndrome type VI)


(PLOD)


procollagen-proline, 2-
1
M24486
+
+
+
+
+
+


oxoglutarate 4-dioxygenase


(proline 4-hydroxylase), alpha


polypeptide 1 (P4HA1)


procollagen-proline, 2-
4
X05130
+
+
+
+
+
+


oxoglutarate 4-dioxygenase


(proline 4-hydroxylase), beta


polypeptide (protein disulfide


isomerase; thyroid hormone


binding protein p55) (P4HB)


profilin 1 (PFN1)
1
J03191
+
+
+
+
+
+


progesterone receptor-
2
U28918

+


associated p48 protein (P48)


prohibitin (PHB)
1
S85655

+
+
+
+
+


proliferating cell nuclear
3
J04718
+
+
+
+

+


antigen (PCNA)


proliferation-associated gene
4
L19184
+
+
+
+
+
+


A (natural iller-enhancing


factor A) (PAGA)


proline-rich protein B stNI
1
S62936


subfamily 2 (PRB2) (non-


exact, 43% aa)


proline-serine-threonine
1
U94778


phosphatase interacting


protein 1 (PSTPIP1)


prolyl endopeptidase (PREP)
2
X74496

+

+

+


prolylcarboxypeptidase
5
L13977

+
+
+
+
+


(angiotensinase C) (PRCP)


promyelocytic leukemia
1
M80185
+
+
+
+

+


(PML)


properdin P factor,
4
X57748
+


complement (PFC)


pro-platelet basic protein
1
M54995


+
+

+


(includes platelet basic


protein, beta-


thromboglobulin, connective


tissue-activating peptide III,


neutrophil-activating peptide-


2) (PPBP)


pro-platelet basic protein
7
M54995
+

+

+


(includes platelet basic


protein, beta-


thromboglobulin, connective


tissue-activating peptide III,


neutrophil-activating peptide-


2) (PPBP)


proprotein convertase
4
U40623


subtilisin/kexin type 7


(PCSK7)


prosaposin (variant Gaucher
89
D00422
+
+
+
+
+
+


disease and variant


metachromatic


leukodystrophy) (PSAP)


prostaglandin-endoperoxide
1
U63846
B
+


+
+


synthase 1 (prostaglandin G/H


synthase and cyclooxygenase)


(PTGS1)


prostaglandin-endoperoxide
2
L15326


synthase 2 (prostaglandin G/H


synthase and cyclooxygenase)


(PTGS2)


prostaglandin-endoperoxide
1
D64068


synthase-1 (=L08404;


U84208) (all promoters)


prostate carcinoma tumor
2
L78132


antigen (pcta-1)


protease inhibitor 1 (anti-
17
K02212

+
+
+
+
+
high in many libraries


elastase), alpha-1-antitrypsin


(PI)


protease inhibitor 2 (anti-
1
M93056



+

+


elastase), monocyte/neutrophil


(ELANH2) (low match)


proteasome (prosome,
3
L02426
B
+
+


+


macropain) 26S subunit,


ATPase, 1 (PSMC1)


proteasome (prosome,
1
M34079
+
+
+
+

+


macropain) 26S subunit,


ATPase, 3 (PSMC3)


proteasome (prosome,
2
AF020736


macropain) 26S subunit,


ATPase, 4 (PSMC4)


proteasome (prosome,
5
L38810
+
+
+
+
+
+


macropain) 26S subunit,


ATPase, 5 (PSMC5)


proteasome (prosome,
2
D78275
+
+
+
+

+


macropain) 26S subunit,


ATPase, 6 (PMSC6)


proteasome (prosome,
1
AF001212
T
+


+


macropain) 26S subunit, non-


ATPase, 11 (PSMD11)


proteasome (prosome,
2
D78151

+
+


+


macropain) 26S subunit, non-


ATPase, 2 (PSMD2)


proteasome (prosome,
1
S79862
T
+
+

+


macropain) 26S subunit, non-


ATPase, 5 (PSMD5)


proteasome (prosome,
1
D50063

+
+
+

+
high in many libraries


macropain) 26S subunit, non-


ATPase, 7 (Mov34 homolog)


(PMSD7)


proteasome (prosome,
1
AB003103

+
+
+

+


macropain) 26S subunit, on-


ATPase, 12 (PMSD12)


proteasome (prosome,
3
L07633
+
+
+
+

+


macropain) activator subunit 1


(PA28 alpha) (PSME1)


proteasome (prosome,
2
D00762

+
+
+

+


macropain) subunit, alpha


type, 3 (PSMA3)


proteasome (prosome,
3
X61970
+
+
+
+

+


macropain) subunit, alpha


type, 5 (PSMA5)


proteasome (prosome,
3
AF054185

+
+
+
+
+


macropain) subunit, alpha


type, 7 (PSMA7)


proteasome (prosome,
1
AF022815


macropain) subunit, alpha


type, 7 (PSMA7) (low match)


proteasome (prosome,
1
D00761
+
+
+
+
+
+


macropain) subunit, beta type,


1 (PSMB1)


proteasome (prosome,
1
X71874
+
+

+
+
+


macropain) subunit, beta type,


10 (PSMB10)


proteasome (prosome,
1
D29012

+
+
+

+


macropain) subunit, beta type,


6 (PMSB6)


proteasome (prosome,
1
U17497
+
+
+
+

+


macropain) subunit, beta type,


8 (large multifunctional


protease 7) (PSMB8)


proteasome (prosome,
3
Z14977
+


+

+


macropain) subunit, beta type,


9 (large multifunctional


protease 2) (PSMB9)


proteasome (prosome,
1
D38048
+
+
+
+
+
+


macropain) subunit, beta ype,


7 (PSMB7)


protective protein for beta-
3
M22960
+
+
+
+
+
+


galactosidase


(galactosialidosis) (PPGB)


protein A alternatively spliced
1
U47925

+


form 2 (A-2)


protein activator of the
1
AF072860

+
+
+

+
high in testis


interferon-induced protein


kinase (PACT)


protein disulfide isomerase-
2
D49489
+
+
+
+
+
+


related protein (P5)


protein
1
L25441
+
+
+


geranylgeranyltransferase type


I, beta subunit (PGGT1B)


protein homologous to
20
M24194
+
+
+
+
+
+
high in many libraries


chicken B complex protein,


guanine nucleotide binding


(H12.3)


protein kinase A anchoring
1
AF037439

+


protein


protein kinase C substrate
2
U50317
+
+
+
+

+


80K-H (PRKCSH)


protein kinase C, beta 1
6
X06318
+
+
+
+

+


(PRKCB1)


protein kinase C, delta
1
D10495
+
+
+
+

+


(PRKCD)


protein kinase C, eta
1
M55284


+


+


(PRKCH)


protein kinase C, mu
1
X75756


(PRKCM) (non-exact 78%)


Protein kinase C-like 1
2
D26181
+
+
+
+

+


(PRKCL1)


protein kinase, AMP-
1
U42412
B, T
+
+


activated, gamma 1 non-


lymphoma


catalytic subunit (PRKAG1)


protein kinase, cAMP-
4
M18468

+
+
+
+
+


dependent, regulatory, type I,


alpha (tissue specific


extinguisher 1) (PRKAR1A)


protein kinase, DNA-
1
U47077

+
+

+
+


activated, catalytic


polypeptide (PRKDC)


protein kinase, mitogen-
1
Z11695
B
+


+


activated 1 (MAP kinase 1;


p40, p41) (PRKM1)


protein kinase, mitogen-
1
L77964

+

+
+
+


activated 6 (extracellular


signal-regulated kinase, p97)


(PRKM6)


protein kinase, mitogen-
1
U66839
+
+
+
+
+


activated, kinase 3 (MAP


kinase kinase 3) (PRKMK3)


protein phosphatase 1,
5
M63960
+
+
+
+
+
+


catalytic subunit, alpha


isoform (PPP1CA)


protein phosphatase 1,
3
Y13247

+
+
+

+


regulatory subunit 10


(PPPR10)


protein phosphatase 1,
2
Z50749
+
+
+
+
+
+


regulatory subunit 7


(PPP1R7)


protein phosphatase 2
1
X12656
+
+
+
+
+
+


(formerly 2A), catalytic


subunit, beta isoform


(PPP2CB)


protein phosphatase 2
1
L07590


+
+

+


(formerly 2A), regulatory


subunit B′′ (PR 72), alpha


isoform and (PR 130), beta


isoform (PPP2R3)


protein phosphatase 2,
2
L42373
+
+
+
+

+


regulatory subunit B (B56),


alpha isoform (PPP2R5A)


protein phosphatase 2,
3
D78360

+
+
+

+


regulatory subunit B (B56),


delta isoform (PPP2R5D)


protein phosphatase 2,
1
D26445
+
+
+
+

+


regulatory subunit B (B56),


gamma isoform (PPP2R5C)


protein phosphatase 2A
5
J02902
+
+
+
+

+


regulatory subunit alpha-


isotype (alpha-PR65)


protein phosphatase 4
2
AF097996
+
+
+
+

+


(formerly X), catalytic subunit


(PPP4C)


protein tyrosine kinase 2 beta
4
L49207

+

+

+


(PTK2B)


protein tyrosine phosphatase
1
X54134


epsilon


protein tyrosine phosphatase
2
L48723
+
+
+
+

+


type IVA, member 2


(PTP4A2)


protein tyrosine phosphatase,
1
M31724
+
+
+
+


non-receptor type 1 (PTPN1)


protein tyrosine phosphatase,
1
M93425

+
+
+

+
high in testis


non-receptor type 12


(PTPN12)


protein tyrosine phosphatase,
1
M93425


non-receptor type 12


(PTPN12) (non-exact, 70%)


protein tyrosine phosphatase,
2
M25393

+
+
+

+


non-receptor type 2 (PTPN2)


protein tyrosine phosphatase,
1
M68941


+
+

+


non-receptor type 4


(megakaryocyte) (PTPN4)


protein tyrosine phosphatase,
7
M74903
+
+
+
+

+


non-receptor type 6 (PTPN6)


protein tyrosine phosphatase,
1
D11327
+


+

+


non-receptor type 7 (PTPN7)


protein tyrosine phosphatase,
1
M34668
+
+
+
+

+


receptor type, alpha


polypeptide (PTPRA)


protein tyrosine phosphatase,
44
Y00638
+
+

+

+


receptor type, c polypeptide


(PTPRC)


protein tyrosine phosphatase,
1
X58288

+
+
+

+


receptor type, M (PTPRM)


protein tyrosine phosphatase,
2
U81561

+

+

+


receptor type, N polypeptide 2


(PTPRN2)


protein with polyglutamine
1
U94836
+
+
+
+

+


repeat (ERPROT213-21)


protein-kinase, interferon-
1
U28424

+
+
+
+
+


inducible double stranded


RNA dependent inhibitor


(PRKRI)


protein-L-isoaspartate (D-
4
D13892

+
+


aspartate) O-methyltransferase


(PCMT1)


proteoglycan 1, secretory
7
J03223

+

+

+


granule (PRG1)


prothymosin, alpha (gene
12
M14483
+
+
+
+
+
+


sequence 28) (PTMA)


prp28, U5 snRNP 100 kd
7
AF026402
+
+
+
+

+


protein (U5-100K)


PRP4/STK/WD splicing
1
AF001687

+
+
+

+


factor (HPRP4P)


PTK7 protein tyrosine kinase
1
U40271

+
+
+

+


7 (PTK7)


purinergic receptor P2X,
3
AF000234

+
+
+

+


ligand-gated ion channel, 4


(P2RX4)


purinergic receptor P2X,
1
Y12851
+





macrophage only


ligand-gated ion channel, 7


(P2RX7)


puromycin-sensitive
1
Y07701

+
+


+


aminopeptidase (PSA)


putative ATP(GTP)-binding
2
AJ010842

+



+


protein


putative brain nuclearly-
1
AB018308
+
+
+
+

+


targeted protein (KIAA0765)


putative chemokine receptor;
1
D10923
+


GTP-binding protein (HM74)


putative dienoyl-CoA
1
AF030249


isomerase (ECH1)


putative G-binding protein
1
AF065393


Putative human HLA class II
1
U73477
B
+


+


associated protein I (PHAP1)


Putative L-type neutral amino
1
AB007896


acid transporter (KIAA0436)


putative mitochondrial space
1
AF050198


protein 32.1


PUTATIVE MUCIN CORE
1
Q04900


PROTEIN PRECURSOR 24


(MULTI-GLYCOSYLATED


CORE PROTEIN 24) (MGC-


24) (MUC-24)


putative nucleic acid binding
2
X76302
+
+
+
+

+


protein


putative outer mitochondrial
1
U58970

+
+
+

+


membrane 34 kDa translocase


Htom34


putative p150 (non-exact
1
U93568


88%)


putative translation initiation
1
L26247
+
+
+
+
+
+
High in moderately


factor (SUI1)








differentiated colon











adenocarcinoma


putative tumor suppressor
1
AF061836

+
+
+

+


protein (123F2)


pyrroline 5-carboxylate
1
M77836
+
+
+
+

+


reductase


pyruvate dehydrogenase
1
D90084

+
+
+
+
+


(lipoamide) alpha 1 (PDHA1)


pyruvate dehydrogenase
2
J03576
+
+
+
+

+


(lipoamide) beta (PDHB)


Pyruvate dehydrogenase
3
Y13145

+
+


complex, lipoyl-containing


component X; E3-binding


protein (PDX1)


pyruvate kinase, muscle
11
M23725




+


(PKM2)


RAB, member of RAS
1
U18420

+
+
+

+


oncogene family-like (RABL)


RAB1, member RAS
3
M28209

+
+
+

+


oncogene family (RAB1)


RAB11A, member RAS
2
X56740
+
+
+
+

+
high in spleen


oncogene family (RAB11A)


RAB11B, member RAS
1
D45418

+



+


oncogene family (Rab11B)


RAB27A, member RAS
3
U38654



+


oncogene family (RAB27A)


RAB5B, member RAS
1
X54871

+
+
+

+


oncogene family (RAB5B)


RAB6, member RAS
1
M28212

+



+


oncogene family (RAB6)


RAB7, member RAS
1
X93499
+
+
+
+

+


oncogene family (RAB7)


RAB7, member RAS
2
D84488

+
+
+

+


oncogene family-like 1


(RAB7L1)


RAB9, member RAS
1
U44103


oncogene family (RAB9)


RAD50 (S. cerevisiae)
2
U63139

+
+
+


homolog (RAD50)


RAD51 (S. cerevisiae)
1
AF029669

+
+
+

+


homolog C (RAD51C)


Radin blood group (RD)
2
L03411

+
+
+

+


RAE1 (RNA export 1,
3
U84720
+
+
+
+

+


S. pombe) homolog (RAE1)


ralA-binding protein
2
L42542
+
+
+
+


(RLIP76)


RAN binding protein 2-like 1
2
AF012086


(RANBP2L1)


Ran GTPase activating protein
3
X82260
+
+
+
+

+


1 (RANGAP1)


RAN, member RAS oncogene
1
M31469


family (RAN) (low match)


RanBP2 (Ran-binding protein
1
D42063


2) (=U19248; L41840 sapiens


nucleoporin (NUP358))


ransforming growth factor,
4
D50683
+
+
+
+

+


beta receptor II (70-80 kD)


(TGFBR2)


RAP1A, member of RAS
10
M22995
+
+
+
+
+
+


oncogene family (RAP1A)


RAR-related orphan receptor
1
U16997





+


C (RORC)


RAS guanyl releasing protein
1
Y12336
+
+


2 (calcium and DAG-


regulated)


ras homolog gene family,
12
X05026
+
+
+
+
+
+
high in ovary


member A (ARHA)


ras homolog gene family,
1
X61587
+
+
+
+


member G (rho G) (ARHG)


ras homolog gene family,
2
Z35227
+
+
+


+


member H (ARHH)


ras inhibitor (RIN1)
2
M37191

+


Ras-GTPase activating protein
2
AF053535
+
+
+
+

+


SH3 domain-binding protein 2


(KIAA0660)


Ras-GTPase-activating
3
U32519
+
+
+
+

+


protein SH3-domain-binding


protein (G3BP)


ras-related C3 botulinum
11
M29871


+


+


toxin substrate 2 (rho family,


small GTP binding protein


Rac2) (RAC2)


RAS-RELATED PROTEIN
1
P09526


RAP-1B (GTP-BINDING


PROTEIN SMG P21B)


RBQ-1
1
X85133

+
+
+


rearranged T cell receptor beta
1
L06891


variable region (TCRB)


(=X58810)


regulator of Fas-induced
1
AF057557
B



+


apoptosis (TOSO)


regulator of G protein
1
AF073920

+


signalling 6 (RGS6)


regulator of G-protein
2
AF037195
+
+
+
+


signalling 14 (RGS14)


regulator of G-protein
6
L13391
+
+
+
+

+


signalling 2, 24 kD (RGS2)


regulator of G-protein
1
O15539


signalling 5 (RGS5) (49% aa)


regulatory factor X, 4
1
M69297


+
+


(influences HLA class II


expression) (RFX4)


regulatory factor X, 5
2
X85786
T
+
+


+


(influences HLA class II


expression (RFX5)


replication protein A1
1
M63488
+
+
+
+

+


(RPA1)


replication protein A3 (14 kD)
1
L07493


(RPA3) (low match)


reproduction 8 (D8S2298E)
1
D83767

+
+
+


requiem, apoptosis response
2
U94585
+
+
+
+

+


zinc finger gene (REQ)


requiem, apoptosis response
1
U94585


zinc finger gene (REQ)


(=AF001433) (low match)


restin (Reed-Steinberg cell-
1
M97501
B, T
+
+


expressed intermediate


filament-associated protein)


(RSN)


retinoblastoma 1 (including
3
L11910
+
+
+
+


osteosarcoma) (RB1)


retinoblastoma binding
1
AF087481


protein 2 homolog 1


(RBBP2H1)


retinoblastoma-binding
1
S66427
+
+


protein 1 (RBBP1)


retinoblastoma-binding
5
S66431
+
+
+
+

+


protein 2 (RBBP2)


retinoblastoma-binding
1
X71810

+
+
+

+


protein 4 (RBBP4)


retinoblastoma-binding
1
X74262

+
+
+

+


protein 4 (RBBP4)


retinoblastoma-binding
1
U35143


protein 7 (RBBP7)


retinoblastoma-like 2 (p130)
1
X76061

+
+
+

+


(RBL2)


retinoic acid receptor
1
AF060228

+

+
+
+


responder (tazarotene nduced)


3 (RARRES3)


retinoic acid receptor, alpha
1
X06538
+
+

+


(RARA)


retinoic acid responsive
1
U50383

+

+

+


(NN8-4AG)


retinoid X receptor beta
2
X66424

+
+
+

+


(RXR-beta)


REV3 (yeast homolog)-like,
1
AF035537


catalytic subunit of DNA


polymerase zeta (REV3L)


Rho GDP dissociation
23
L07916
+
+
+
+
+
+


inhibitor (GDI) beta


(ARHGDIB)


Rho GTPase activating
2
X78817
+
+


protein 4 (ARHGAP4)


Rho GTPase activating
1
P98171


protein 4 (ARHGAP4) (low


match)


Rho-associated, coiled-coil
1
AB014519


containing protein kinase 2


(ROCK2)


ribonuclease 6 precursor
2
U85625
+
+
+
+
+
+


(RNASE6PL)


ribonuclease 6 precursor
1
U85625


(RNASE6PL) (low match)


ribonuclease, RNase A family,
1
X55988




+


2 (liver, eosinophil-derived


neurotoxin) (RNASE2)


ribonuclease/angiogenin
3
M36717
+
+
+
+

+


inhibitor (RNH)


ribonucleoside diphosphate
1
X65708


reductase M1 subunit


ribonucleotide reductase M2
1
P31350


polypeptide (non-exact 91%)


ribophorin I (RPN1)
1
Y00281
+
+
+
+

+


ribophorin II (RPN2)
1
Y00282
+
+
+
+
+
+


ribosomal 18S rRNA
3
M10098


ribosomal 28S RNA
1
M11167


ribosomal phosphoprotein P0,
1
D28418


5′UTR (low match)


Ribosomal protein
1


ribosomal protein L10
30
L25899
+
+
+
+
+
+
high in many libraries


(RPL10)


RIBOSOMAL PROTEIN
2
P53025


L10A (CSA-19)


ribosomal protein L11
4
X79234
+
+
+
+
+
+
Alveolar


(RPL11)








rhabdomyosarcoma


ribosomal protein L12
2
L06505
+
+
+
+
+
+


(RPL19)


ribosomal protein L13
1
P26373
+
+
+
+
+
+
high in many libraries


(PRL13)


ribosomal protein L14
4
D87735
+
+
+
+
+
+
high in many libraries


(RPL14)


ribosomal protein L17
4
X53777
+





blood only


(RPL17)


ribosomal protein L18
10
L11566
+
+
+
+

+


(RPL18)


ribosomal protein L18a
5
L05093

+
+
+
+
+
High in fetal adrenal


(RPL18A)








gland and skin


ribosomal protein L18a
2
X80821



+


homologue


ribosomal protein L19
15
X63527
+
+
+
+
+
+


(RPL19)


ribosomal protein L21
6
U14967
+
+
+
+
+
+


(RPL21)


ribosomal protein L22
3
D17652
+
+
+
+

+


(RPL22)


ribosomal protein L23
2
X55954
+
+
+
+
+
+
high in many libraries


(RPL23)


ribosomal protein L23a
5
U37230
+
+
+
+
+
+
high in many libraries


(RPL23A)


ribosomal protein L26
8
X69392
+
+
+
+
+
+


(RPL26)


ribosomal protein L27
6
L05094
+
+
+
+

+


(RPL27)


ribosomal protein L27a
10
U14968
+
+
+
+
+
+


(RPL27A)


ribosomal protein L28
6
U14969
+
+
+
+

+


(RPL28)


ribosomal protein L29
6
U10248
+
+
+
+
+
+


(RPL29)


ribosomal protein L3 (RPL3)
81

+
+
+
+
+
+
high in many libraries


ribosomal protein L3
81
X06323


homologue


ribosomal protein L30
6
X79238
+
+
+
+
+
+
high in lymphoma


(RPL30)


ribosomal protein L30
1
X79238


(RPL30) (low score)


ribosomal protein L31
10
X15940
+
+
+
+
+
+
High in alveolar


(RPL31)








rhabdomyosarcoma


ribosomal protein L32
3
X03342
+
+
+
+
+
+


(RPL32)


ribosomal protein L33-like
1
AF047440

+
+
+

+


(RPL33L)


ribosomal protein L34
5
L38941

+
+
+
+
+


(RPL34)


ribosomal protein L34
1
L38941


(RPL34) (low match)


ribosomal protein L37
5
D23661
+
+
+
+
+
+
high in barstead


(RPL37)








prostate


ribosomal protein L37a
4
X66699
+
+
+
+
+
+
high in many libraries


ribosomal protein L38
1
Z26876
+
+
+
+
+
+
high in many libraries


(PRL38)


ribosomal protein L4 (RPL4)
27
D23660
+
+
+
+
+
+
high in many libraries


ribosomal protein L41
4
AF026844
+
+
+
+
+
+
high in many libraries


(RPL41)


ribosomal protein L5 (RPL5)
14
U14966
+
+
+
+
+
+
High in alveolar











rhabdomyosarcoma


ribosomal protein L5 (RPL5)
1
U14966


(low match)


ribosomal protein L6 (RPL6)
7
X69391
+
+
+
+
+
+
high in many libraries


ribosomal protein L7 (RPL7)
14
X52967
+
+
+
+
+
+
high in conorm


ribosomal protein L7a
15
M36072
+
+
+
+
+
+
High in uterus, and


(RPL7A)








seminoma


ribosomal protein L8 (RPL8)
5
Z28407
+
+
+
+
+
+
high in ovary


ribosomal protein L9 (RPL9)
10
U09953

+
+
+
+
+


ribosomal protein S10
5
U14972
+
+
+
+
+
+
high in many libraries


(RPS10)


ribosomal protein S11
4
X06617
+
+
+
+
+
+
high in many libraries


(RPS11)


ribosomal protein S11
1
AB007152


(RPS11) (low match)


ribosomal protein S12
3
X53505
+
+
+
+
+
+
high in many libraries


(RPS12)


ribosomal protein S13
2
L01124

+
+
+
+
+


(RPS13)


ribosomal protein S14
12
M13934
+
+
+
+
+
+


(RPS14)


ribosomal protein S15
2
M32405
+
+
+
+
+
+


(RPS15)


ribosomal protein S16
3
M60854
+
+
+
+
+
+
High in prostate


(RPS16)








invasive tumor


ribosomal protein S17
2
M13932
+
+
+
+
+
+
high in many libraries


(RPS17)


ribosomal protein S18
8
X69150


ribosomal protein S19
7
M81757
+
+
+
+
+
+
high in many libraries


(RPS19)


ribosomal protein S2 (RPS2)
4
X17206
+
+
+
+
+
+
high in many libraries


RIBOSOMAL PROTEIN S2
2
P15880


(RPS4)


ribosomal protein S20
7
L06498
+
+
+
+
+
+
high in many libraries


(RPS20)


ribosomal protein S21
3
L04483
+
+
+
+
+
+
high in CD34+/CD38−


(RPS21)








hematopoietic cells and











skin tumor


ribosomal protein S23
3
D14530

+
+
+

+


(RPS23)


ribosomal protein S24
7
M31520
+
+
+
+
+
+
high in uterus


(RPS24)


ribosomal protein S25
3
M64716
+
+
+
+
+
+
high in barstead


(RPS25)








prostate


ribosomal protein S26
2
X69654

+
+
+
+
+


(RPS26)


ribosomal protein S27
5
U57847
+
+
+
+
+
+


((metallopanstimulin 1)


(RPS27)


ribosomal protein S28
3
U58682
+
+
+
+

+


(RPS28)


ribosomal protein S29
2
U14973
+
+
+
+
+
+


(RPS29)


ribosomal protein S3 (RPS3)
9
X55715
+
+
+
+
+
+
high in many libraries


ribosomal protein S3 (RPS3)
1
U14990


(low match)


ribosomal protein S3A
21
Z83334

+
+
+
+
+
high in many libraries


(RPS3A)


ribosomal protein S3A
1
M77234


(RPS3A) (low score)


ribosomal protein S4, X-
9
M58458
+
+
+
+

+
high in ovary and


linked (RPS4X)








Synovial sarcoma


ribosomal protein S4, Y-
2
M58459
+
+
+
+
+
+


linked (RPS4Y)


ribosomal protein S5 (RPS5)
4
U14970
+
+
+
+
+
+
high in lymphoma


RIBOSOMAL PROTEIN S6
1
P10660


(PHOSPHOPROTEIN NP33)


ribosomal protein S6 (RPS6)
22
M20020
+
+
+
+
+
+


ribosomal protein S6 (RPS6)
1
M77232


(non-exact 86%)


ribosomal protein S6 kinase,
3
L07597
+
+
+
+

+


90 kD, polypeptide 1


(RPS6KA1)


ribosomal protein S6 kinase,
1
X85106


90 kD, polypeptide 2


(RPS6KA2)


ribosomal protein S7 (RPS7)
4
Z25749

+
+
+
+
+


ribosomal protein S8 (RPS8)
6
X67247

+
+
+
+
+


ribosomal protein S9 (RPS9)
8
U14971






colon tumor


ribosomal protein, large, P0
18
M17885
T

+


+


(RPLP0)


ribosomal protein, large, P1
12
M17886
T
+
+

+


(RPLP1)


ribosomal RNA 18S
11
X03205


(=M10098; K03432)


(=polyadenylating sequence)


ribosomal RNA 28S
2
M11167


ribosomal RNA, 16S
1
U25123


ring finger protein (non-exact
1
AJ001019


58%)


ring finger protein 3 (RNF3)
1
AJ001019


ring finger protein 4 (RNF4)
3
AB000468

+
+
+

+


ring zinc-finger protein
3
U41315

+
+
+

+


(ZNF127-Xp)


RNA (guanine-7-)
1
AB007858

+
+
+

+


methyltransferase (RNMT)


RNA binding motif protein 5
4
U23946
+
+
+
+

+


(RBM5)


RNA binding motif, single
1
D28483

+

+

+


stranded interacting protein 2


(RBMS2)


RNA helicase (putative),
1
X98743
+
+
+
+

+


(Myc-regulated DEAD box


protein) (MRD8)


RNA helicase-related protein
1
AF083255

+
+
+

+


RNA pol II largest subunit
2
X74872


RNA polymerase I subunit
1
AF008442

+
+


+


(RPA40)


RTVP-1 protein
2
X91911
+
+
+
+

+


S100 calcium-binding protein
2
M81457


+

+
+


A10 (annexin II ligand,


calpactin I, light polypeptide


(p11)) (S100A10)


S100 calcium-binding protein
1
X80201

+
+
+

+


A11 (calgizzarin) (S100A11)


S100 calcium-binding protein
3
M80563
B

+

+


A4 (calcium protein,


calvasculin, metastasin,


murine placental


homolog)(S100A4)


S100 calcium-binding protein
7
M21005


+
+

+
high in bone marrow


A8 (calgranulin A) (S100A8)


S100 calcium-binding protein
14
X06233


+
+


high in invasive larynx


A9 (calgranulin B) (S100A9)








squamous cell











carcinoma


S164 gene
1
AF109907


S-adenosylmethionine
3
M88003
+
+
+
+

+


decarboxylase 1 (AMD1)


SB classII histocompatibility
5
M27487
+
+
+
+

+


antigen alpha-chain


SC35-interacting protein 1
5
AF030234
+
+
+
+
+
+


(SRRP129)


scaffold attachment factor B
1
U72355
+
+
+
+

+


(SAFB)


scaffold attachment factor B
1
U72355


(SAFB) (non-exact 78%)


scRNA molecule, transcribed
1
L13713


from Alu repeat


SEC14 (S. cerevisiae)-like
4
D67029

+
+
+

+


(SEC14L)


SEC23-like protein B
2
X97065
+
+
+
+

+


(SEC23B)


SEC63 (SEC63)
1
AF100141

+
+


+


secreted protein, acidic,
7
M25746

+
+
+
+
+
high in bone marrow


cysteine-rich (osteonectin)








stroma


(SPARC)


secretory carrier membrane
1
AF038966

+

+


protein 1 (SCAMP1)


secretory carrier membrane
1
AF005038
+
+
+
+
+
+


protein 2 (SCAMP2)


secretory carrier membrane
1
AF005039


protein 3 (SCAMP3)


secretory granule
1
M33649


proteoglycan core (clones


lambda-PG[6,7,8])


selectin L (lymphocyte
43
X17519
+


+

+


adhesion molecule 1) (SELL)


selectin P ligand (SELPLG)
13
U02297
+
+


sema domain,
2
U60800

+

+

+


immunoglobulin domain (Ig),


transmembrane domain (TM)


and short cytoplasmic domain,


(semaphorin) 4D (SEMA4D)


Ser/Arg-related nuclear matrix
4
AF048977

+
+
+
+
+


protein (plenty of prolines


101-like) (SRM160)


serine palmitoyltransferase
1
Y08685

+
+
+

+


subunit I (SPTI)


serine palmitoyltransferase,
1
AB011098
+
+
+
+

+


subunit II (LCB2)


serine protease
1
J02907


serine protease inhibitor,
1
U78095
+
+
+
+

+


Kunitz type, 2 (SPINT2)


serine/threonine kinase 10
1
AB015718
+
+
+
+

+


(STK10)


serine/threonine kinase 19
1
L26260
+
+
+
+


(STK19)


serine/threonine kinase 4
1
U18297

+



+


(STK4)


serine/threonine protein
1
X66358

+
+
+

+


kinase KKIALRE


(KKIALRE)


serine/threonine protein-
1
Y10256

+
+
+


kinase (NIK)


SERINE/THREONINE-
1
P37023


PROTEIN KINASE


RECEPTOR R3


PRECURSOR (SKR3)


serologically defined colon
2
AF039694


cancer antigen 16 (NY-CO-


16)


serologically defined colon
1
AF039698
B, T
+
+

+


cancer antigen 33


(SDCCAG33)


serologically defined colon
1
AF039698


cancer antigen 33


(SDCCAG33) (low score)


serologically defined colon
1
AF039698


cancer antigen 33


(SDCCAG33) (low score)


serum deprivation response
1
AF085481.1


(phosphatidylserine-binding


protein) (SDPR) (=S67386)


serum/glucocorticoid
2
Y10032
+
+
+
+

+


regulated kinase (SGK)


SET domain, bifurcated 1
2
D31891
+
+
+


+


(SETDB1)


SH2 domain protein 1A,
1
AF073019
T




+


Duncan's disease


lymphoproliferative


syndrome) (SH2D1A)


SH3 binding protein (SAB)
2
AB005047
+
+
+
+

+


SH3 domain protein 1B
4
U61167
+


+

+


(SH3D1B)


SH3BGR PROTEIN (=21-
1
P55822


GLUTAMIC ACID-RICH


PROTEIN; 21-GARP) (non-


exact 82% aa)


SH3-binding domain glutamic
1
AF042081
+
+
+
+

+


acid-rich protein like


(SH3BGRL)


SH3-domain GRB2-like 1
1
U65999
+
+
+
+

+


(SH3GL1)


SHC (Src homology 2
2
X68148

+
+
+

+


domain-containing)


transforming protein 1


(SHC1)


siah binding protein 1
2
U51586

+
+
+

+


(SiahBP1)


siah binding protein 1
1
U51586


(SiahBP1) (non-exact, 69%)


Sialomucin CD164 (CD164)
9
D14043


sialophorin (gpL115,
2
J04536


leukosialin, CD43) (SNP)


sialyltransferase (STHM)
1
U14550


+
+

+


sialyltransferase 1 (beta-
2
X17247
+
+
+
+
+
+


galactoside alpha-2,6-


sialytransferase) (SIAT1)


sialyltransferase 4A (beta-
1
AF059321
B
+
+

+
+


galactosidase alpha-2,3-


sialytransferase) (SIAT4A)


sialyltransferase 8 (alpha-2,8-
1
L41680

+


polysialytransferase) D


(SIAT8D)


signal peptidase 25 kDa
1
L38950


subunit


signal recognition particle
1
X73459
+
+
+
+
+
+


14 kD (homologous Alu RNA-


binding protein) (SRP14)


signal recognition particle
1
U51920


+
+

+


54 kD (SRP54)


signal recognition particle
2
U20998

+
+
+
+
+


9 kD (SRP9)


signal recognition particle
5
X06272


receptor (‘docking protein’)


SRPR


signal regulatory protein, beta,
5
Y10376

+



+


1 (SIRP-BETA-1)


signal sequence receptor,
2
Z12830



+

+


alpha (translocon-associated


protein alpha) (SSR1)


signal sequence receptor, beta
2
X74104
+
+
+
+

+


(translocon-associated protein


beta) (SSR2)


signal transducer and activator
4
L41142
+
+
+
+
+
+


of transcription (STAT5A)


signal transducer and activator
1
U18671





+


of transcription 2, 113 KD


(STAT2)


signal transducer and activator
3
L29277


of transcription 3 (acute-phase


response factor) (STAT3)


signal transducer and activator
2
U48730
+
+
+
+
+
+


of transcription 5A (STAT5A)


signal transducing adaptor
1
U43899


molecule (SH3 domain and


ITAM motif) 1 (STAM)


silencing mediator of retinoid
1
U37146


and thyroid hormone action


(SMRT)


similar to beta-transducin
1
U02609
+
+
+


+


superfamily proteins (SAZD)


similar to S. cerevisiae SSM4
1
AB011169

+
+
+

+


(TEB4)


similar to yeast pre-mRNA
1
AF026031
+
+
+
+

+


splicing factors, Prp1/Zer1


and Prp6


SIT protein
1
AJ010059.1


Sjogren syndrome antigen A1
2
M62800




+


(52 kD, ribonucleoprotein


autoantigen SS-A/Ro) (SSA1)


Sjogren syndrome antigen A1
1
M62800


(52 kD, ribonucleoprotein


autoantigen SS-A/Ro) (SSA1)


(non-exact 63%) (match to


zinc finger)


SKAP55 homologue (SKAP-
1
AJ004886

+
+
+

+


HOM)


skb1 (S. pombe) homolog
2
AF015913
+
+
+
+

+


(SKB1)


skeletal muscle abundant
1
X87613
+
+
+
+

+


protein


SMA3 (SMA3)
1
X83300
+
+

+

+


small acidic protein
3
U51678
+
+
+
+

+


small EDRK-rich factor 2
2
Y10351
+
+
+
+
+
+
high in fetal lung


(SERF2)


small inducible cytokine A5
2
M21121
+
+
+
+
+
+
high in many libraries


(RANTES) (SCYA5)


small inducible cytokine
1
D63789


subfamily C, member 2


(SCYC2)


small nuclear
2
M15841

+
+
+

+


ribonucleoprotein polypeptide


B′′ (SNRPB2)


small nuclear
4
J04615
+
+
+
+
+
+


ribonucleoprotein polypeptide


N (SNRPN)


small nuclear
2
J04564
+
+
+
+

+


ribonucleoprotein


polypeptides B and B1


(SNRPB)


small nuclear RNA activating
1
AF093593
+
+
+
+

+


complex, polypeptide 5, 19 kD


(SNAPC5)


smallest subunit of ubiquinol-
1
D55636
+
+
+
+
+
+
high in fetal lung


cytochrome c reductase


SMC (mouse) homolog, X
1
L25270
+
+
+
+

+


chromosome (SMCX)


SMT3B protein (2)
2
X99585
+
+
+
+
+
+


SNARE protein (YKT6) (low
1
U95735


match)


SNC19
1
U20428


SNC73 protein (SNC73)
2
J00220
+
+

+
+
+
high in many libraries


solute carrier family 1 (neutral
2
U53347

+

+

+


amino acid transporter),


member 5 (SLC1A5)


Solute carrier family 11
7
D50403
+


(proton-coupled divalent


metal ion transporters),


member 1 (SLC11A1)


solute carrier family 17
1
U90545



+


(sodium phosphate), member


3 (SLC17A3)


solute carrier family 19 (folate
1
U17566
B, lymphoma
+


+


transporter), member 1


(SLC19A1)


solute carrier family 2
1
K03195
+
+
+
+
+
+


(facilitated glucose


transporter), member 1


(SLC2A1)


solute carrier family 23
3
D87075

+
+
+

+


(nucleobase transporters),


member 2 (SLC23A2)


solute carrier family 25
1
AF070548
B, T
+
+

+
+


(mitochondrial carrier;


oxoglutarate carrier), member


11 (SLC25A11)


solute carrier family 31
3
U83461

+

+


(copper transporters), member


2 (SLC31A2)


solute carrier family 4, anion
1
X62137

+
+


+


exchanger, member 2


(erythrocyte membrane


protein band 3-like 1)


(SLC4A2)


solute carrier family 4, sodium
1
AB018282

+


bicarbonate cotransporter,


member 8 (SLC4A8)


solute carrier family 7
2
M80244
T, W
+
+

+


(cationic amino acid


transporter, y+ system),


member 5 (SLC7A5)


solute carrier family 7
3
D87432
+
+
+


+


(cationic amino acid


transporter, y+ system),


member 6 (SLC7A6)


solute carrier family 7
1
D87432


(cationic amino acid


transporter, y+ system),


member 6 (SLC7A6) (non-


exact 77%)


solute carrier family 9
1
AF030409

+
+
+

+


(sodium/hydrogen exchanger),


isoform 6 (SLC9A6)


somatic cytochrome c (HCS)
2
M22877


SON DNA binding protein
2
X63753

+
+
+

+


(SON)


son of sevenless (Drosophila)
1
L13858
+
+

+


homolog 1 (SOS1)


sorcin (SRI)
1
M32886


sortilin 1 (SORT1)
2
X98248

+

+

+


sortilin-related receptor,
6
Y08110


L(DLR class) A repeats-


containing (SORL1)


sorting nexin 1 (SNX1)
3
U53225
+
+
+
+

+


sorting nexin 2 (SNX2)
2
AF043453


sorting nexin 6 (SNX6)
1
AF121856.1


(=U83194.1 TRAF4-


associated factor 2)


Sp3 transcription factor (SP3)
1
X68560
+
+
+
+

+


Sp3 transcription factor (SP3)
4
M97191
+
+
+
+

+


special AT-rich sequence
1
M97287


binding protein 1 (binds to


nuclear matrix/scaffold-


associating DNA's) (SATB1)


speckle-type POZ protein
4
AJ000644


(SPOP)


speckle-type POZ protein
1
AJ000644


(SPOP) (non-exact)


spectrin SH3 domain binding
6
U87166
+
+
+
+


protein 1 (SSH3BP1)


Spectrin, alpha, non-
2
J05243

+
+


+


erythrocytic 1 (alpha-fodrin)


(SPTAN1)


spermidine/spermine N1-
11
M55580


acetyltransferase (SAT)


spermidine/spermine N1-
1
U40369


acetyltransferase (SAT) (non-


exact, 84%)


spermine synthase (SMS)
1
AD001528
+
+
+
+

+


SPF31 (SPF31)
1
AF083190
+
+
+
+

+


sphingomyelin
1
X52679

+
+

+


phosphodiesterase 1, acid


lysosomal (acid


sphingomyelinase) (SMPD1)


SPINDLIN HOMOLOG
1
Q99865


(PROTEIN DXF34)


spinocerebellar ataxia 1
3
X79204
B
+


+


(olivopontocerebellar ataxia 1,


autosomal dominant, ataxin 1)


(SCA1)


spinocerebellar ataxia 2
1
U70323
B



+


(olivopontocerebellar ataxia 2,


autosomal dominant, ataxin 2)


(SCA2)


spinocerebellar ataxia 7
2
AJ000517

+


(olivopontocerebellar atrophy


with retinal degeneration)


(SCA7)


spliceosome associated
3
U41371

+
+
+
+
+


protein (SAP 145)


splicing factor (CC1.3)
2
L10910
+
+
+
+
+
+


(CC1.3)


splicing factor SRp40-1
7
U30826
+
+
+
+
+
+


(SRp40)


splicing factor,
3
M74002
B
+
+

+
+


arginine/serine-rich 11


(SFRS11)


splicing factor,
4
L41887

+
+
+

+


arginine/serine-rich 7 (35 kD)


(SFRS7)


Src-like adapter protein (non-
1
U30473


exact, 76% aa)


Src-like-adapter (SLA)
6
D89077

+
+
+

+


Src-like-adapter (SLA) (low
1
D89077


match)


Src-like-adapter (SLA) (low
1
U44403


score)


stannin (SNN)
2
AF030196
+
+
+
+

+


STAT induced STAT
1
AB004904



+


inhibitor 3 (SSI-3)


STE20-like kinase 3 (MST-3)
2
AF024636
+
+
+
+

+


step II splicing factor SLU7
1
AF101074

+

+
+
+


(SLU7)


steroid sulfatase
1
M17591


steroid sulfatase (microsomal),
1
J04964

+
+
+


arylsulfatase C, isozyme S


(STS)


sterol carrier protein 2 (SCP2)
1
M55421

+
+
+
+
+


sterol O-acyltransferase (acyl-
1
AF059202




+


Coenzyme A: cholesterol


acyltransferase) 1 (SOAT1)


stimulated trans-acting factor
6
X82200
+
+

+


(50 kDa) (STAF50)


Striatin, calmodulin-binding
1
U17989


protein (STRN) (low match,


71% aa)


Stromal antigen 2 (STAG2)
2
Z75331


+
+
+
+


stromal interaction molecule 1
3
U52426
+
+
+
+

+


(STIM1)


structure specific recognition
1
M86737

+
+
+

+


protein 1 (SSRP1)


succinate dehydrogenase
5
L21936


+


complex, subunit A,


flavoprotein (Fp) (SDHA)


succinate dehydrogenase
1
U17248
+
+
+
+

+


complex, subunit B, iron


sulfur (Ip) (SDHB)


succinate dehydrogenase
1
U57877
+
+
+
+

+


complex, subunit C, integral


membrane protein, 15 kD


(SDHC)


succinate dehydrogenase
3
AB006202

+
+

+


complex, subunit D, Integral


membrane protein (SDHD)


succinate-CoA ligase, GDP-
1
AF058954

+
+
+
+
+


forming, beta subunit


(SUCLG2)


succinyl CoA synthetase
1
Z68204


sudD (suppressor of bimD6,
2
AF013591

+


+
+


Aspergillus nidulans)


homolog (SUDD)


sulfotransferase family 1A,
1
L19999

+


+
+


phenol-preferring, member 1


(SULT1A1)


sulfotransferase family 1A,
1
U37686


phenol-preferring, member 3


(SULT1A3) (non-exact 67%)


superoxide dismutase 1,
4
X02317

+
+

+
+


soluble (amyotrophic lateral


sclerosis 1 (adult)) (SOD1)


superoxide dismutase 2,
5
Y00985

+
+
+
+
+


mitochondrial (SOD2)


supervillin (SVIL)
2
AF051851


+
+

+


suppression of tumorigenicity
2
U15131

+

+

+


5 (ST5)


suppression of tumorigenicity
1
U15779


5 (ST5) (non-exact 82%)


suppressor of K+ transport
1
AF038960


+
+


defect 1 (SKD1)


suppressor of Ty
1
AF064804
+
+
+
+

+


(S. cerevisiae) 3 homolog


(SUPT3H)


suppressor of Ty
2
U38817
+
+
+
+

+


(S. cerevisiae) 4 homolog 1


(SUPT4H1)


suppressor of Ty
2
U56402

+



+


(S. cerevisiae) 5 homolog


(SUPT5H)


suppressor of Ty
2
U46691
+
+
+
+
+
+


(S. cerevisiae) 6 homolog


(SUPT6H)


suppressor of variegation 3-9
1
AF019968

+
+
+


(Drosophila) homolog 1


(SUV39H1)


survival of motor neuron 1,
1
U18423


telomeric (SMN1)


SWI/SNF related, matrix
1
M88163


+
+

+


associated, actin dependent


regulator of chromatin,


subfamily a, member 1


(SMARCA1) (non-exact,


75%)


SWI/SNF related, matrix
2
D26155

+


associated, actin dependent


regulator of chromatin,


subfamily a, member 2


(SMARCA2)


SWI/SNF related, matrix
1
D26156
+
+
+
+
+
+


associated, actin dependent


regulator of chromatin,


subfamily a, member 4


(SMARCA4)


SWI/SNF related, matrix
4
U66616
+
+
+
+
+
+


associated, actin dependent


regulator of chromatin,


subfamily c, member 2


(SMARCC2)


SWI/SNF related, matrix
2
AF035262
B, W
+
+

+
+


associated, actin dependent


regulator of chromatin,


subfamily e, member 1


(SMARCE1)


synaptobrevin-like 1 (SYBL1)
1
X95803

+
+
+

+


synaptosomal-associated
2
AJ011915

+
+
+

+


protein, 23 kD (SNAP23)


syndecan binding protein
15
AF006636
+
+
+
+

+


(syntenin) (SDCBP)


synovial sarcoma, translocated
2
X79201

+


to X chromosome (SSXT)


syntaxin 16
1
AF038897


syntaxin 3A (STX3A)
2
U32315

+

+

+


syntaxin 6 (STX6)
1
AJ002078.1


SYNTAXIN BINDING
1
O00186


PROTEIN 3 (UNC-18


HOMOLOG 3) (UNC-18C)


syntaxin-16C
1
AF008937


SYT interacting protein (SIP)
1
AF080561

+
+
+

+


T cell activation, increased
4
M88282



+


late expression (TACTILE)


T cell receptor V alpha gene
2
X58744


segment V-alpha-7 (clone


IGRa11)


T cell receptor V alpha gene
1
X58740


segment V-alpha-w27


T3 receptor-associating
5
S83390
+
+
+
+
+
+


cofactor-1


tafazzin (cardiomyopathy,
1
X92763
+
+

+

+


dilated 3A (X-linked);


endocardial fibroelastosis 2;


Barth syndrome) (TAZ)


TAFII100 protein (non-exact
1
U80191


53%)


tankyrase, TRF1-interacting
1
AF082556

+
+
+

+


ankyrin-related ADP-ribose


polymerase (TNKS)


TAP1, TAP2, LMP2, LMP7
1
X66401


and DOB


TAR DNA-binding protein-43
6
U23731
+
+
+
+

+


Tat interactive protein (60 kD)
2
U40989
+
+
+
+

+


(TIP60)


TATA box binding protein
1
O00268


(TBP)-associated factor, RNA


polymerase II, C1, 130 kD


(TAF2C1) (non-exact, 55%)


TATA box binding protein
4
X97999

+
+
+
+
+


(TBP)-associated factor, RNA


polymerase II, F, 55 kD


(TAF2F)


TATA box binding protein
2
U21858

+
+
+
+
+


(TBP)-associated factor, RNA


polymerase II, G, 32 kD


(TAF2G)


TATA box binding protein
1
D63705
+
+
+
+

+


(TBP)-associated factor, RNA


polymerase II, I, 28 kD


(TAF2I)


Tax1 (human T-cell leukemia
1
U33821

+
+
+
+
+


virus type I) binding protein 1


(TAX1BP1)


T-box 2 (TBX2) (non-exact
1
U28049


+
+

+


77%)


TBP-associated factor 172
1
AJ001017

+

+

+


(TAF-172)


T-cell death-associated gene 8
1
U95218



+


(TDAG8)


T-cell leukemia/lymphoma 1A
1
X82240
+


(TCL1A)


T-cell leukemia/lymphoma 1A
1
X82240


(TCL1A) (low match)


T-cell receptor (delta D2-J1-
1
M22197


region) (clone K3B)


T-cell receptor (V beta 5.1, J
1
M97705


beta 1.5, C beta 1) (low


match)


T-cell receptor alpha delta
2
AE000662


(=M94081)


T-cell receptor alpha
1
B39625


enhancer-binding protein,


short form (=X58636 Mouse


LEF1 lymphoid enhancer


binding factor 1 (=D16503))


T-cell receptor delta gene D2-
1
M22197


J1-region, clone K3B


T-cell receptor germline beta
1
M11955


chain gene V-region (V) V-


beta-MT1-1


T-cell receptor germline beta-
1
M14159
+





only in blood


chain gene J2.1 exon


T-cell receptor germline delta-
2
M22152


chain D-J region


T-cell receptor interacting
2
AJ224878





+


molecule (TRIM) protein


T-cell receptor rearranged
1
M21784


delta-chain, V-region (V-delta


3-J)


T-cell receptor, alpha
3
AE000660
+
+
+
+

+


(V, D, J, C) (TCRA)


T-cell receptor, beta cluster
3
L34740
+
+
+
+
+
+
high in pancreas


(TCRB)


T-cell receptor, delta
2
X73617


+
+

+


(V, D, J, C) (TCRD)


T-cell, immune regulator 1
3
U45285






only found in tumor


(TCIRG1)


TCF-1 mRNA for T cell factor 1
1
X59870


TCF-1 mRNA for T cell factor
1
X59870


1 (splice form B) (low match)


T-COMPLEX PROTEIN 1,
1
Q99832


ETA SUBUNIT (TCP-1-


ETA) (CCT-ETA) (HIV-1


NEF INTERACTING


PROTEIN)


T-COMPLEX PROTEIN 1,
1
P50990


THETA SUBUNIT (TCP-1-


THETA) (CCT-THETA)


(KIAA0002)


TCR eta = T cell receptor(eta-
1
S94421


exon)


TCR V Beta 13.2
1
X75419


TERA
1
AC004472


testis enhanced gene transcript
33
X75861
+
+
+
+
+
+


(TEGT)


tetracycline transporter-like
2
L11669

+
+
+

+


protein (TETRAN)


tetratricopeptide repeat
1
U46570
+
+
+
+

+


domain 1 (TTC1)


tetratricopeptide repeat
1
U46571

+

+

+


domain 2 (TTC2)


tetratricopeptide repeat
1
D84296
+
+
+
+

+


domain 3 (TTC3)


TGFB1-induced anti-
1
D86970
+
+
+
+

+


apoptotic factor 1 (TIAF1)


thioredoxin reductase 1
3
S79851

+
+
+

+


(TXNRD1)


THIOREDOXIN-
1
P30048


DEPENDENT PEROXIDE


REDUCTASE PRECURSOR,


mitochondrial (ANTI-


OXIDANT PROTEIN 1)


(AOP-1)


threonyl-tRNA synthetase
1
M63180

+
+
+

+


(TARS)


thrombin inhibitor
1
Z22658


thrombospondin 1 (THBS1)
2
X04665

+
+
+
+
+


thromboxane A synthase 1
1
M80647

+

+
+
+


(platelet, cytochrome P450,


subfamily V) (TBXAZ1)


thymidine kinase 2,
2
X76104

+
+

+


mitochondrial (TK2)


thymidylate kinase (CDC8)
1
L16991

+
+
+

+


thymine-DNA glycosylase
2
U51166
+
+
+
+

+


(TDG)


Thymosin, beta 10 (TMSB10)
2
M20259
+
+
+
+
+
+


thymosin, beta 4, X
29
M17733

+
+
+

+


chromosome (TMSB4X)


thyroid autoantigen 70 kD (Ku
7
J04611


antigen) (G22P1)


thyroid hormone receptor
1
AF016270

+

+

+


coactivating protein (SMAP)


thyroid hormone receptor
2
L40357

+
+
+

+


interactor 7 (TRIP7)


thyroid hormone receptor
4
L40411

+


interactor 8r (TRIP8)


thyroid hormone receptor-
1
D83783


associated protein, 230 kDa


subunit (TRAP230)


thyroid receptor interacting
2
L40388
+
+
+
+


protein 15 (TRIP15)


TI-227H
1
D50525


TIA1 cytotoxic granule-
1
M77142

+
+
+

+


associated RNA-binding


protein (TIA1)


tissue inhibitor of
1
X02598
+
+
+
+
+
+


metalloproteinase 1 (erythroid


potentiating activity,


collagenase inhibitor)


(TIMP1)


tissue inhibitor of
1
M32304
+
+
+
+

+
high in placenta


metalloproteinase 2 (TIMP2)


tissue specific transplantation
1
U58766
+
+
+
+

+


antigen P35B (TSTA3)


titin (TTN)
1
X64697
+
+
+
+

+
high in muscle


TNF receptor-associated
1
U12597

+
+
+

+


factor 2 (TRAF2)


TNF receptor-associated
1
AF110908.1

+


factor 3 (TRAF3)


TNF receptor-associated
1
U78798


factor 6 (TRAF6) (low match)


toll-like receptor 1 (TLR1)
1
U88540



+


toll-like receptor 2 (TLR2)
1
U88878
+
+

+

+


toll-like receptor 4 (TLR4)
1
U88880

+


+


toll-like receptor 5 (TILR5)
1
AF051151

+

+


topoisomerase (DNA) I
1
J03250

+
+
+


(TOP1)


topoisomerase (DNA) II beta
2
X68060
+
+
+
+

+


(180 kD) (TOP2B)


topoisomerase (DNA) III beta
3
D87012
+


(TOP3B)


TR3beta
1
D85245

+


TRAF family member-
3
U63830
+
+
+
+
+
+


associated NF-kB activator


(TANK)


TRANSALDOLASE
1
P37837


transaldolase 1 (TALDO1)
4
L19437

+
+
+
+
+


transaldolase-related protein
1
AF010398


transcobalamin II (TCII)
1
AF047576


transcription elongation factor
2
Z47087
+
+
+
+

+


B (SIII), polypeptide 1-like


(TCEB1L)


transcription elongation factor
1
L47345
+
+
+
+
+
+


B (SIII), polypeptide 3


(110 kD, elongin A) (TCEB3)


transcription factor 12 (HTF4,
1
M83233
+
+
+
+

+


helix-loop-helix transcription


factors 4) (TCF12)


transcription factor 17
2
D89928

+

+


(TCF17)


transcription factor 4 (TCR4)
2
X52079

+
+
+

+


transcription factor 6-like 1
2
M62810
+
+
+
+


(mitochondrial transcription


factor 1-like) (TCF6L1)


transcription factor 7-like 2
1
Y11306

+
+
+

+


(T-cell specific, HMG-box)


(TCF7L2)


transcription factor binding to
1
X96717
+
+
+
+

+


IGHM enhancer 3 (TFE3


transcription factor IL-4 Stat
7
AF067575
+
+
+
+
+
+


transcription factor IL-4 Stat
1
U16031


(low match)


transcription factor ISGF-3
4
M97935


(=M97936)


transcription factor REST
1
A56138


transcription factor TFIID
1
Z22828


transcriptional adaptor 2
1
AF064094


(ADA2, yeast, homolog)-like


(TADA2L)


transcriptional intermediary
1
AF009353


factor 1 (TIF1) (non-exact


72%)


transducin (beta)-like 1
1
Y12781
+
+
+
+

+


(TBL1)


transducin-like enhancer of
1
M99438
+
+


split 3, homolog of


Drosophila E(sp1) (TLE3)


Transformation/transcription
1
AF076974
+
+
+
+

+


domain-associated protein


(TRRAP)


transformation-sensitive,
2
M86752

+
+
+

+


similar to Saccharomyces


cerevisiae STI1 (STI1L)


transforming growth factor
1
AB009356


beta-activated kinase 1


(TAK1) (non-exact 78%)


transforming growth factor
3
AJ222700
+
+
+
+

+


beta-stimulated protein TSC-


22 (TSC22)


transforming growth factor,
1
L07594

+
+
+

+


beta receptor III (betaglycan,


300 kD) (TGFBR3)


transforming growth factor,
2
4507466
+
+
+
+
+
+


beta-induced, 68 kD (TGFBI)


TRANSFORMING
2
Q15582


GROWTH FACTOR-BETA


INDUCED PROTEIN IG-H3


PRECURSOR (BETA IG-H3)


transforming, acidic coiled-
1
AF049910


coil containing protein 1


(TACC1) (non-exact 70%)


transgelin 2 (TAGLN2)
14
D21261
+
+
+
+
+
+


transgelin 2 (TAGLN2) (non-
1
D21261


exact)


trans-Golgi network protein
2
AF029316

+

+


(46, 48, 51 kD isoforms)


(TGN51)


transient receptor potential
1
X89066

+
+
+

+


channel 1 (TRPC1)


transketolase (Wernicke-
7
L12711

+
+
+

+


Korsakoff syndrome) (TKT)


translation factor sui1
1
AF064607

+
+
+
+
+


homolog (GC20)


translin (TSN)
3
X78627
+
+
+
+

+


translin-associated factor X
1
X95073

+
+
+

+


(TSNAX)


transmembrane glycoprotein
1
U79725


(A33)


transmembrane protein
1
X69910
+
+
+
+

+


(63 kD), endoplasmic


reticulum/Golgi intermediate


compartment (P63)


transmembrane protein 1
1
AB001523

+

+

+


(TMEM2)


TRANSMEMBRANE
1
P51805


PROTEIN SEX


PRECURSOR (non-exact


65%)


transmembrane trafficking
2
X97442
+
+
+
+
+
+


protein (TMP21)


transporter 1, ABC (ATP
3
L21208
+
+
+
+

+


binding cassette) (TAP1)


Treacher Collins-
2
U40847
+
+
+
+

+
high in many libraries


Franceschetti syndrome 1


(TCOF1)


triosephosphate isomerase 1
2
X69723
+
+
+
+
+
+


(TPI1)


tropomyosin
2
X04201

+
+
+

+


tropomyosin 4 (TPM4)
2
X05276
+
+
+
+

+


TRPM-2 protein
2
M63376


tryptase I precursor (non-exact
1
A35863


64%)(=P20231)


tryptophan rich basic protein
1
Y12478


(WRB)


tryptophanyl-tRNA synthetase
1
X59892
+
+
+
+
+
+


(WARS)


Ts translation elongation
1
L37936
+
+

+

+


factor, mitochondrial (TSFM)


ttopoisomerase (DNA) II beta
1
Z15115

+
+


+


(180 kD)


Tu translation elongation
4
L38995


factor, mitochondrial (TUFM)


tuberous sclerosis 1 (TSC1)
1
AF013168

+
+
+

+


tuberous sclerosis 2 (TSC2)
1
X75621

+
+
+

+


tubulin, alpha 1 (testis
1
X06956

+


+


specific) (TUBA1)


tubulin, alpha, ubiquitous (K-
11
K00558
+
+
+
+
+
+
high in many libraries


ALPHA-1)


tubulin, alpha, ubiquitous (K-
1
K00558


ALPHA-1) (low match)


tubulin-specific chaperone c
1
U61234

+
+
+

+


(TBCC)


tumor necrosis factor (ligand)
7
U37518

+
+
+

+


superfamily, member 10


(TNFSF10)


tumor necrosis factor (ligand)
1
AF046888
+
+

+

+


superfamily, member 13


(TNFSF13)


tumor necrosis factor (ligand)
1
AF036581


superfamily, member 14


(TNFSF14)


tumor necrosis factor (ligand)
1
D38122
+





Found only in library


superfamily, member 6








386: T-cell lymphoma


(TNFSF6)


tumor necrosis factor (ligand)
1
L09753
B only


superfamily, member 8


(TNFSF8)


tumor necrosis factor alpha-
1
AF061034

+
+
+

+


inducible cellular protein


containing leucine zipper


domains (FIP2)


Tumor necrosis factor
2
M63928

+


+


receptor superfamily member


7 (TNFRSF7)


tumor necrosis factor receptor
1
AF016266

+
+
+
+
+


superfamily, member 10b


(TNFRSF10B)


tumor necrosis factor receptor
3
AF012629




+


superfamily, member 10c,


decoy without an intracellular


domain (TNFRSF10C)


tumor necrosis factor receptor
1
AF023849






found only in prostate


superfamily, member 10d,


decoy with truncated death


domain (TNFRSF10D) (non-


exact 84%)


tumor necrosis factor receptor
1
U94508
+
+
+
+

+


superfamily, member 12


(translocating chain-


association


membrane protein)


(TNFRSF12)


tumor necrosis factor receptor
1
U70321
+
+
+
+

+


superfamily, member 14


(herpesvirus entry mediator)


(TNFRSF14)


tumor necrosis factor receptor
5
U52165
+
+
+
+

+


superfamily, member 1B


(TNFRSF1B)


tumor necrosis factor receptor
1
X63717
B, W




+


superfamily, member 6


(TNFRSF6)


tumor necrosis factor receptor
1
M63928
+
+


superfamily, member 7


(TNFRSF7)


tumor necrosis factor, alpha-
8
M92357

+
+

+


induced protein 2 (TNFAIP2)


tumor necrosis factor, alpha-
2
M59465


induced protein 3 (TNFAIP3)


tumor protein 53-binding
1
AF078776

+
+
+

+


protein, 1 (TP53BP1)


tumor protein p53 (Li-
1
M14695
+
+



+


Fraumeni syndrome) (TP53)


Tumor protein p53-binding
1
U82939
+


+

+


protein (TP53BPL)


tumor protein, translationally-
35
X16064


controlled 1 (TPT1)


tumor protein, translationally-
1
X16064


controlled 1 (TPT1) (low


score)


tumor rejection antigen (gp96)
9
X15187
+
+
+
+
+
+


1 (TRA1)


tumorous imaginal discs
2
AF061749

+


(Drosophila) homolog (TID1)


TXK tyrosine kinase (TXK)
2
L27071


type II integral membrane
1
AJ001685




+

found only in fetal


protein (NKG2-E)








liver/spleen


TYRO protein tyrosine kinase
3
AF019562


+


binding protein (TYROBP)


tyrosine 3-
1
X57346
+
+
+
+

+
high in ecnorm


monooxygenase/tryptophan 5-


monooxygenase activation


protein, beta polypeptide


(YWHAB)


tyrosine 3-
1
M86400


monooxygenase/tryptophan 5-


monooxygenase activation


protein, zeta polypeptide


(YWHAZ)


tyrosine 3-
1
M86400


monooxygenase/tryptophan 5-


monooxygenase activation


protein, zeta polypeptide


(YWHAZ)


Tyrosine kinase 2 (TYK2)
3
X54637

+
+
+

+


TYROSINE-PROTEIN
2
P43403


KINASE ZAP-70 (70 KD


ZETA-ASSOCIATED


PROTEIN) (SYK-RELATED


TYROSINE KINASE)


tyrosyl-tRNA synthetase
1
U89436
+
+
+
+

+


(YARS)


U1 small nuclear RNA
1
M14387


U19H snoRNA (=M63485
1
AJ224166


R. norvegicus matrin 3)


U2(RNU2) small nuclear
1
M96982

+
+
+

+


RNA auxillary factor 1 (non-


standard symbol) (U2AF1)


U22 snoRNA host gene
2
U40580


(UHG)


U4/U6-associated RNA
4
AF016370

+
+
+

+


splicing factor (HPRP3P)


U49 small nuclear RNA
1
X96649


U5 snRNP-specific protein
1
AB007510
+
+
+
+

+


(220 kD), ortholog of S. cerevisiae


Prp8p (PRP8)


U5 snRNP-specific protein,
4
D21163
+
+
+
+

+


116 kD (U5-116 KD)


U5 snRNP-specific protein,
3
Z70200


200 kDa (DEXH RNA


helicase family) (U5-200-KD)


Uba80 mRNA for ubiquitin
4
S79522
+
+
+
+
+
+
high in ovary


ubiquinol-cytochrome c
1
D55636
+
+
+
+
+
+
high in fetal lung


reductase (6.4 kD) subunit


(UQCR)


UBIQUINOL-
1
P47985


CYTOCHROME C


REDUCTASE IRON-


SULFUR SUBUNIT


PRECURSOR (RIESKE


IRON-SULFUR PROTEIN)


(RISP) (low match)


ubiquitin A-52 residue
2
X56999


ribosomal protein fusion


product 1 (UBA52)


ubiquitin activating enzyme
1
AF094516

+
+


+


E1-like protein (GSA7)


ubiquitin C (UBC)
5
AB009010

+
+
+
+
+
high in ovary


ubiquitin carboxyl-terminal
1
M30496
+
+
+
+

+


esterase L3 (ubiquitin


thiolesterase) (UCHL3)


ubiquitin fusion degradation
1
U64444
+
+
+
+

+


1-like (UFD1L)


ubiquitin protein ligase E3A
1
U84404
B
+
+


+


(human papilloma virus E6-


associated protein, Angelman


syndrome) (UBE3A)


ubiquitin specific protease 10
4
D80012
+
+
+
+

+


(USP10)


ubiquitin specific protease 11
1
U44839
+
+
+
+
+
+


(USP11)


ubiquitin specific protease 15
3
AB011101
+
+
+
+

+


(USP15)


ubiquitin specific protease 19
1
AB020698

+


(USP19)


ubiquitin specific protease 4
1
AF017305
B
+
+

+
+


(proto-oncogene) (USP4)


ubiquitin specific protease 4
1
AF017306


(proto-oncogene) (USP4)


(non-exact, 66%)


ubiquitin specific protease 7
1
Z72499

+
+
+

+


(herpes virus-associated)


(USP7)


ubiquitin specific protease 8
5
D29956

+
+
+

+


(USP8)


UBIQUITIN-ACTIVATING
1
P22314


ENZYME E1 (A1S9


PROTEIN) (56%)


ubiquitin-activating enzyme
1
M58028
+
+
+
+

+


E1 (A1S9T and BN75


temperature sensitivity


complementing) (UBE1)


ubiquitin-activating enzyme
1
L34170
+
+

+

+


E1, like (UBE1L)


UBIQUITIN-BINDING
1
U41806


+

+


PROTEIN P62;


phosphotyrosine independent


ligand for the Lck SH2


domain p62 (P62)


ubiquitin-conjugating enzyme
2
U49278
+
+
+
+
+
+


E2 variant 1 (UBE2V1)


ubiquitin-conjugating enzyme
1
X98091


E2 variant 2 (UBE2V2)


UBIQUITIN-
1
Q16781


CONJUGATING ENZYME


E2-17 KD (UBIQUITIN-


PROTEIN LIGASE)


ubiquitin-conjugating enzyme
1
M74525
+
+
+
+

+


E2B (RAD6 homolog)


(UBE2B)


ubiquitin-conjugating enzyme
1
AF032456
+
+
+
+

+


E2G 2 (homologous to yeast


UBC7) (UBE2G2)


ubiquitin-conjugating enzyme
1
Z29328
+
+
+
+

+


E2H (homologous to yeast


UBC8) (UBE2H)


ubiquitin-conjugating enzyme
1
X92962

+
+


+


E2L 1 (UBE2L1)


ubiquitin-conjugating enzyme
3
AJ000519

+
+
+

+


E2L 3 (UBE2L3)


ubiquitin-conjugating enzyme
4
AF031141

+
+
+
+
+


E2L 6 (UBE2L6)


ubiquitin-like 1 (sentrin)
2
U61397
+
+
+
+

+


(UBL1)


UDP-N-acetyl-alpha-D-
2
X85019


galactosamine:polypeptide N-


acetylgalactosaminyltransferase


2 (GalNAc-T2) (GALNT2)


UDP-N-acetyl-alpha-D-
1
X92689


galactosamine:polypeptide N-


acetylgalactosaminyltransferase 3


(GalNAc-T3) (GALNT3)


(non-exact 65%)


unactive progesterone
2
L24804

+
+
+

+


receptor, 23 Kd (P23)


unconventional myosin-ID
3
U57053


(MYO1F)


uncoupling protein homolog
1
U94592


(UCPH)


uncoupling protein homolog
1
U94592


(UCPH) (low match 67%)


Unknown gene product
1
AC002310


unknown mRNA (clone
1
AF070542


24514)


unknown protein (clone
2
Z70223


ICRFp507L0677)


unknown protein (Hs.93832)
1
AF070626
+
+
+
+
+
+


unknown protein IT14
1
AF040966


uppressor of Ty (S. cerevisiae)
1
D79984
+
+
+
+
+
+


6 homolog


upregulated by 1,25-
74
S73591
+
+
+
+

+
high in heart


dihydroxyvitamin D-3


(VDUP1)


upregulated by 1,25-
1
S73591


dihydroxyvitamin D-3


(VDUP1) (low match)


upregulated by 1,25-
1
S73591


dihydroxyvitamin D-3


(VDUP1) (low match)


upregulated by 1,25-
1
S73591


dihydroxyvitamin D-3


(VDUP1) (low score)


upstream binding factor
1
X53461
+
+

+

+


(hUBF)


UV radiation resistance
2
X99050

+
+
+

+


associated gene (UVRAG)


vacuolar proton-ATPase,
4
X71490

+
+
+
+
+


subunit D; V-ATPase, subunit


D (ATP6DV)


v-akt murine thymoma viral
1
M63167
+
+
+
+

+


oncogene homolog 1 (AKT1)


Vanin 2 (VNN2)
3
AJ132100


vasodilator-stimulated
3
Z46389
+

+
+

+


phosphoprotein (VASP)


vav 1 oncogene (VAV1)
1
M59834





+


vav 2 oncogene (VAV2)
1
S76992
+
+


v-crk avian sarcoma virus
1
D10656
W
+
+

+


CT10 oncogene homolog


(CRK)


v-erb-b2 avian erythroblastic
1
M29366





+


leukemia viral oncogene


homolog 3 (ERBB3)


VERSICAN CORE
1
P13611


PROTEIN PRECURSOR


Vesicle-associated membrane
1
M36196

+
+
+

+


protein 1 (synaptobrevin 1)


(VAMP1)


vesicle-associated membrane
1
U64520


protein 3 (cellubrevin)


(VAMP3)


v-fos FBJ murine
26
K00650

+
+
+
+
+
high in aorta


osteosarcoma viral oncogene


homolog (FOS)


v-fos FBJ murine
1
K00650


osteosarcoma viral oncogene


homolog (FOS) (low match)


villin 2 (ezrin) (VIL2)
1
X51521
+
+
+
+

+


villin-like protein
1
D88154


vimentin (VIM)
12
X56134

+
+
+
+
+
high in many libraries


vinculin (VCL)
4
M33308

+
+
+

+


vitamin A responsive;
6
AF070523

+
+
+

+


cytoskeleton related (JWA)


v-jun avian sarcoma virus 17
2
U65928
+
+
+
+

+


oncogene homolog (JUN)


v-myb avian myeloblastosis
1
M15024


+

+


viral oncogene homolog


(MYB)


voltage-dependent anion
1
L06132
+
+
+
+

+


channel 1 (VDAC1)


voltage-dependent anion
4
U90943

+
+
+

+


channel 3 (VDAC3)


von Hippel-Lindau syndrome
1
L15409

+
+
+

+


(VHL)


von Willebrand factor (vWF)
1
X06828


(low matched)


v-raf murine sarcoma 3611
2
L24038
+
+
+
+


viral oncogene homolog 1


(ARAF1)


v-raf-1 murine leukemia viral
1
X03484
+
+
+
+

+


oncogene homolog 1 (RAF1)


v-ral simian leukemia viral
3
M35416


oncogene homolog B (ras


related; GTP binding protein)


(RALB)


V-rel avian
1
L19067

+
+
+

+


reticuloendotheliosis viral


oncogene homolog A (nuclear


factor of kappa light


polypeptide gene enhancer in


B-cells 3 (p65)) (RELA)


v-yes-1 Yamaguchi sarcoma
2
M16038
+
+

+

+


viral related oncogene


homolog (LYN)


WD repeat domain 1 (WDR1)
1
AB010427
+
+
+
+
+
+


WDR1 (=AF020260)
1
AF020056


WD-repeat protein (HAN11)
2
U94747

+
+


+


Williams-Beuren syndrome
12
AF045555
+
+
+
+
+
+


chromosome region 1


(WBSCR1)


Wiskott-Aldrich syndrome
4
X86019
+
+
+


+


protein interacting protein


(WASPIP)


X (inactive)-specific transcript
2
M97168


(XIST)


xeroderma pigmentosum,
3
D21089
+
+
+
+


complementation group C


(XPC)


XIAP associated factor-1
2
X99699



+


XIB
1
X90392

+
+

+
+


X-linked anhidroitic
1
AF003528


ectodermal dysplasia


X-ray repair complementing
1
M30938
+
+
+
+

+
high in spleen


defective repair in Chinese


hamster cells 5 (double-


strand-break


rejoining; Ku autoantigen,


80 kD) (XRCC5)


XRP2 protein
1
AJ007590


yeloid differentiation primary
1
U84408

+
+
+

+


response gene (88) (MYD88)


zeta-chain (TCR) associated
1
L05148
+


+


protein kinase (70 kD)


(ZAP70)


zeta-chain (TCR) associated
1
L05148


protein kinase (70 kD)


(ZAP70) (low match)


zinc finger protein (Hs.47371)
2
U69274
+
+
+
+

+


zinc finger protein (Hs.78765)
1
U69645
+
+
+
+

+


zinc finger protein 10 (KOX1)
1
X78933





+


(ZNF10)







only


ZINC FINGER PROTEIN
1
Q15973


124 (HZF-16) (non-exact


51%)


zinc finger protein 124 (HZF-
1
S54641


16) (ZNF124) (non-exact,


78%)


ZINC FINGER PROTEIN
1
P52736


133


zinc finger protein 136 (clone
1
U09367


+
+


pHZ-20) (ZNF136)


zinc finger protein 140 (clone
1
U09368

+

+

+


pHZ-39) (ZNF140)


zinc finger protein 140 (clone
1
AF060865


pHZ-39) (ZNF140) (non-


exact 59%)


zinc finger protein 140 (clone
1
U09368


pHZ-39) (ZNF140) (non-


exact 73%)


zinc finger protein 140 (clone
1
S66508


pHZ-39) (ZNF140) (non-


exact 73% aa)


zinc finger protein 140 (clone
1
U09368


pHZ-39) (ZNF140) (non-


exact, 80%)


zinc finger protein 143 (clone
2
U09850
+
+
+
+
+
+


pHZ-1) (ZNF143)


zinc finger protein 143 (clone
1
U09850


pHZ-1) (ZNF143) (low


match)


zinc finger protein 148 (pHZ-
1
AF039019
+


52) (ZNF148)


ZINC FINGER PROTEIN
1
Q13105


151 (MIZ-1 PROTEIN) (low


match)


zinc finger protein 173
1
U09825
B, T
+
+

+


(ZNF173)


zinc finger protein 192
1
U57796


(ZNF192) (non-exact, 66%)


zinc finger protein 198
1
AJ224901

+
+
+


(ZNF198)


zinc finger protein 2 (ZNF2)
1
X60152


(low match)


zinc finger protein 200
1
AF060866

+

+


(ZNF200)


zinc finger protein 207
6
AF046001
+
+
+
+
+
+
high in prostate


(ZNF207)


zinc finger protein 216
2
AF062072
+
+
+
+

+


(ZNF216)


zinc finger protein 217
1
AF041259
T activated




+


(ZNF217)


ZINC FINGER PROTEIN 22
1
P17026


(ZINC FINGER PROTEIN


KOX15) (non-exact 58%)


zinc finger protein 230
1
U95044

+


(ZNF230)


Zinc finger protein 239
1
L26914

+

+


(ANF239)


zinc finger protein 261
1
AB002383

+
+
+

+


(ZNF261)


zinc finger protein 262
1
AB007885

+
+
+

+


(ANF262)


zinc finger protein 263
1
D88827


(ZNF263)


zinc finger protein 264
1
AB007872

+
+
+


(ZNF264)


ZINC FINGER PROTEIN
1
Q06730


33A (ZINC FINGER


PROTEIN KOX31)


(KIAA0065) (HA0946)


zinc finger protein 42
1
M58297
+
+
+
+

+


(myeloid-specific retinoic cid-


responsive) (ZNF42)


zinc finger protein 43 (HTF6)
1
X59244


(ZNF43) (low match)


zinc finger protein 43 (HTF6)
1
X59244


(ZNF43) (non-exact, 54%)


zinc finger protein 43 (HTF6)
1
X59244


(ZNF43) (non-exact, 71%)


ZINC FINGER PROTEIN 43
1
P28160


(ZINC PROTEIN HTF6)


(non-exact 67%)


zinc finger protein 45 (a
1
L75847






only found in testis


Kruppel-associated box


(KRAB) domain polypeptide)


(ZNF45)


ZINC FINGER PROTEIN 46
1
P24278


(ZINC FINGER PROTEIN


KUP) (non-exact 62%)


zinc finger protein 6
1
X56465

+
+
+

+


(CMPX1) (ZNF6)


zinc finger protein 74 (Cos52)
1
X71623


(ZNF74) (non-exact, 67%)


zinc finger protein 76
1
M91592

+
+
+

+


(expressed in testis) (ZNF76)


ZINC FINGER PROTEIN 83
1
P51522


(ZINC FINGER PROTEIN


HPF1) (non-exact 65%)


zinc finger protein 84 (HPF2)
1
M27878
T activated
+
+


+


(ZNF84)


zinc finger protein 85
2
U35376

+
+
+


(ZNF85))


zinc finger protein 9 (ZNF9)
5
M28372

+
+
+
+
+


ZINC FINGER PROTEIN 93
1
P35789


(=ZINC FINGER PROTEIN


HTF34) (non-exact 70%)


zinc finger protein C2H2-25
3
U38904

+
+
+


(ZNF25)


zinc finger protein clone L3-4
1
AF024706


zinc finger protein
4
M92843
+





blood only


homologous to Zfp-36 in


mouse (ZFP36)


ZINC FINGER PROTEIN
1
Q03164


HRX (ALL-1) (71% a.a.)


zinc finger protein HZF4
1
X78927


zinc finger protein RIZ
1
D45132
+
+
+
+

+


zinc finger protein, subfamily
1
U40462
+


1A, 1 (Ikaros) (LYF1)


zinc finger protein, subfamily
1
U40462


1A, 1 (Ikaros) (LYF1) (low


match)


zinc finger transcriptional
1
M92844


regulator (GOS24)


zinc-finger helicase (hZFH)
2
U91543
+
+
+
+

+


Zn-15 related zinc finger
1
U22377

+
+
+


protein (rlf)


Zn-15 related zinc finger
1
U22377


protein (rlf) (non-exact 56%)


ZNF80-linked ERV9 long
1
X83497


terminal repeat


ZW10 (Drosophila) homolog,
2
U54996

+


centromere/kinetochore


protein (ZW10)


zyxin (ZYX)
4
X95735





Column 1: List of unique genes derived from 6,283 known ESTs from blood cells.


Column 2: Number of genes found in randomly sequenced ESTs from blood cells.


Column 3: Accession number.


Column 4: “+” indicates the presence of the unique gene in publicly available cDNA libraries of blood (Bl), brain (Br), heart (H), kidney (K), liver (Li) and lung (Lu).


**Comparison to previously identified tissue-specific genes was determined using the GenBank of the National Centre of Biotechnology Information (NCBI) Database.






Discussion

Every cell and tissue comprising the human body share the necessary genetic information required to maintain cellular homeostasis. These “housekeeping” genes function in basic cellular maintenance, including energy metabolism and cellular structure in all cell types. However, in certain situations, even the housekeeping genes show altered expression. Thus, it is necessary to define the use of these genes as internal controls from one investigation to another. Current results from the human blood cell EST database indicate that over 50% of the transcripts are widely expressed throughout the human body. Most of the cell or tissue specific genes are also detectable in blood cells by RT-PCR analysis.
For example, isoformic myosin heavy chain genes are known to be generally expressed in cardiac muscle tissue. In the rodent, the (MyHC gene is only highly expressed in the fetus and in diseased states such as overt cardiac hypertrophy, heart failure and diabetes; the (MyHC gene is highly expressed shortly after birth and continues to be expressed in the adult heart. In the human, however, (MyHC is highly expressed in the ventricles from the fetal stage through adulthood. This highly expressed (MyHC, which harbours several mutations, has been demonstrated to be involved in familial hypertrophic cardiomyopathy (Geisterfer-Lowrance et al. 1990). It was reported that mutations of (MyHC can be detected by PCR using blood lymphocyte DNA (Ferrie et al., 1992). Most recently, it was also demonstrated that mutations of the myosin-binding protein C in familial hypertrophic cardiomyopathy can be detected in the DNA extracted from lymphocytes (Niimura et al., 1998).
Similarly, APP and APC, which are known to be tissue specific and predominantly expressed in the brain and intestinal tract, are also detectable in the transcripts of blood. These cell- or tissue-specific transcripts are not detectable by Northern blot analysis. However, the low number of transcript copies can be detected by RT-PCR analysis. These findings strongly demonstrate that genes preferentially expressed in specific tissues can be detected by a highly sensitive RT-PCR assay. In recent years, evidence has been obtained to indicate that expression of cell or tissue-restricted genes can be detected in the peripheral blood of patients with metastatic transitional cell carcinoma (Yuasa et al. 1998) and patients with prostate cancer (Gala et al. 1998).
Atrial natriuretic factor (ANF) and zinc finger protein (ZFP), which are known to be highly expressed in heart tissue biopsies and in the plasma of heart failure patients, are also detectable in the transcripts of blood. Differential expression of zinc finger protein among the normal, diabetic and asymptomatic preclinical subjects may have additional value as a prophylactic “early warning system”. On a related note, there is now more attention/discussion in the cardiovascular disease field being focused on Syndrome X, loosely defined as a continuum of hypertension, increasing sugar levels, diabetes, kidney failure, culminating in heart failure, with the possibility of stroke and heart attack at any time in the continuum. The early identification of patients at risk of organ failure has been a challenge to the medical community for some time and the present method has the potential of resolving or, at least, ameliorating this challenge.
The present invention demonstrates that a simple drop of blood may be used to determine the quantitative expression of various mRNAs that reflect the health/disease state of the subject through the use of RT-PCR analysis. This entire process takes about three hours or less. The single drop of blood may also be used for multiple RT-PCR analyses. There is no need for large samples and/or costly and time-consuming separation of cell types within the blood for this method as compared to the methods described by Kimoto (1998) and Chelly et al. (1989; 1988). It is believed that the present finding can potentially revolutionize the way that diseases are detected, diagnosed and monitored because it provides a non-invasive, simple, highly sensitive and quick screening for tissue-specific transcripts. The transcripts detected in whole blood have potential as prognostic or diagnostic markers of disease, as they reflect disturbances in homeostasis in the human body. Delineation of the sequences and/or quantitation of the expression levels of these marker genes by RT-PCR will allow for an immediate and accurate diagnostic/prognostic test for disease or to assess the efficacy and monitor a particular therapeutic.
In addition to RT-PCR, other methods of amplifying may also be used for the purpose of measuring/quantitating tissue-specific transcripts in human blood. For example, mass spectrometry may be used to quantify the transcripts (Koster et al., 1996; Fu et al., 1998). The application of presently disclosed method for detecting tissue-specific transcripts in blood does not restrict to subjects undergoing course of therapy or treatment, it may also be used for monitoring a patient for the onset of overt symptoms of a disease. Furthermore, the present method may be used for detecting any gene transcripts in blood. A kit for diagnosing, prognosing or even predicting a disease may be designed using gene-specific primers or probes derived from a whole blood sample for a specific disease and applied directly to a drop of blood. A cDNA library specific for a disease may be generated from whole blood samples and used for diagnosis, prognosis or even predicting a disease.
The following references were cited herein:

    Claudio J O et al. (1998). Genomics 50:44-52.
    Chelly J et al. (1989). Proc. Nat. Acad. Sci. USA. 86:2617-2621.
    Chelly J et al. (1988). Nature 333:858-860.
    Drews J & Ryser S (1997). Nature Biotech. 15:1318-9.
    Ferrie R M et al. (1992). Am. J. Hum. Genet. 51:251-62.
    Fu D-J et al. (1998). Nat. Biotech 16: 381-4.
    Gala J L et al. (1998). Clin. Chem. 44(3):472-81.
    Geisterfer-Lowrance AAT et al. (1990). Cell 62:999-1006.
    Groden J et al. (1991). Cell 66:589-600.
    Hwang D M et al. (1997). Circulation 96:4146-4203.
    Jandreski M A & Liew C C (1987). Hum. Genet. 76:47-53.
    Jin O et al. (1990). Circulation 82:8-16
    Kimoto Y (1998). Mol. Gen. Genet. 258:233-239.
    Koster M et al. (1996). Nat. Biotech 14: 1123-8.
    Liew & Jandreski (1986). Proc. Nat. Acad. Sci. USA. 83:3175-3179
    Liew C C et al. (1990). Nucleic Acids Res. 18:3647-3651.
    Liew CC (1993). J Mol. Cell. Cardiol. 25:891-894
    Liew C C et al. (1994). Proc. Natl. Acad. Sci. USA. 91:10645-10649.
    Liew et al. (1997). Mol. and Cell. Biochem. 172:81-87.
    Niimura H et al. (1998). New Eng. J. Med. 338:1248-1257.
    Ogawa M (1993). Blood 81:2844-2853.
    Santoro I M & Groden J (1997). Cancer Res. 57:488-494.
    Yuasa T et al. (1998). Japanese J. Cancer Res. 89:879-882.


Any patents or publications mentioned in this specification are indicative of the levels of those skilled in the art to which the invention pertains. Further, these patents and publications are incorporated by reference herein to the same extent as if each individual publication was specifically and individually indicated to be incorporated by reference.
One skilled in the art will appreciate readily that the present invention is well adapted to carry out the objects and obtain the ends and advantages mentioned, as well as those objects, ends and advantages inherent herein. The present examples, along with the methods, procedures, treatments, molecules, and specific compounds described herein are presently representative of preferred embodiments, are exemplary, and are not intended as limitations on the scope of the invention. Changes therein and other uses will occur to those skilled in the art which are encompassed within the spirit of the invention as defined by the scope of the claims.

## Claims

1. A method of profiling gene expression in a human subject having Alzheimer's disease, the method comprising:
determining, for each gene of a set of genes, a level of RNA encoded by the gene in a blood sample of the subject, wherein the set comprises the genes identified as:
100 kDa coactivator; 10 kD protein (BC10); 14-3-3 epsilon; 14-3-3 protein; 15 kDa selenoprotein (SEP15); 1-phosphatidylinositol-4-phosphate 5-kinase isoform C; 23 kD highly basic protein; 2-5A-dependent RNase; 2′-5′oligoadenylate synthetase 2 (OAS2); 26S proteasome subunit 11; 36 kDa phosphothyrosine protein; 3-phosphoglycerate dehydrogenase (PGAD); 3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 1 (PAPSS1); 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; 5′-nucleotidase; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (PFKFB4); 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PF2K); 71 kd heat shock cognate protein hsc70; 76 kDa membrane protein (P76); 8-oxoguanine DNA glycosylase (OGG1); a disintegrin and metalloprotease domain 10 (ADAM10); a disintegrin and metalloprotease domain 8 (ADAM8); A kinase anchor protein 95 (AKAP95); A kinase anchor protein, 149 kD (AKAP149); Absent in melanoma 1 (AIM1); accessory proteins BAP31/BAP29 (DXS1357E); acetyl-Coenzyme A acyltransferase (peroxisomal 3-oxoacyl-Coenzyme A thiolase) (ACAA); acetyl-Coenzyme A transporter (ACATN); acidic 82 kDa protein; acidic protein rich in leucines (SSP29); Aconitase 2, mitochondrial (ACO2); actin binding protein MAYVEN; actin, beta (ACTB); actin, gamma 1 (ACTG1); actin-binding LIM protein (ABLIM); Actinin, alpha 1 (ACTN1); actinin, alpha 4 (ACTN4); activated p21cdc42Hs kinase (ACK); activated RNA polymerase II transcription cofactor 4 (PC4); activating transcription factor 1 (ATF1); activating transcription factor 2 (ATF2); activating transcription factor 4 (tax-responsive enhancer element B67) (ATF4); active BCR-related gene (ABR); acyl-CoA oxidase (AOX); acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain (ACADM); acyl-Coenzyme A dehydrogenase, very long chain (ACADVL); acyloxyacyl hydrolase (neutrophil) (AOAH); adaptin, delta (ADTD); adaptin, gamma (ADTG); adaptor complex sigma3B (AP3S3); adaptor protein p150; adducin 1 (alpha) (ADD1); adducin 1 (alpha) (add1); adducin 3 (gamma) (ADD3); adenine nucleotide translocator 2 (fibroblast) (ANT2); adenine nucleotide translocator 3 (liver) (ANT3); adenomatous polyposis-coli protein (APC); adenosine deaminase, RNA-specific (ADAR); adenylate cyclase 3 (ADCY3); adenylate cyclase 7 (ADCY7); adenylate kinase 2 (AK2); adenylyl cyclase-associated protein (CAP); adipose differentiation-related protein; adipophilin (ADFP); ADP-ribosylation factor 1 (ARF1); ADP-ribosylation factor 3 (ARF3); ADP-ribosylation factor 4 (ARF4); ADP-ribosylation factor 5 (ARF5); ADP-ribosylation factor domain protein 1, 64 kD (ARFD1); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) (ADPRT); adrenergic, beta, receptor kinase 1 (ADRBK1); adrenoleukodystrophy-like 1 (ALDL1); AF-17; A-gamma-globin; A-gamma-globin (chromosome 11 allele); agammaglobulinaemia tyrosine kinase (ATK); AHNAK nucleoprotein (desmoyokin) (AHNAK); alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) (ANPEP); alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5); aldehyde dehydrogenase 1, soluble (ALDH1); aldehyde dehydrogenase 10 (fatty aldehyde dehydrogenase) (ALDH10); aldehyde reductase 1 (low Km aldose reductase) (ALDR1); aldo-keto reductase family 1, member A1 (aldehyde reductase) (AKR1A1); aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (AKR1C3); aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (AKR7A2); aldolase A, fructose-bisphosphate (ALDOA); aldolase C, fructose-bisphosphate (ALDOC); alkaline phosphatase, liver/bone/kidney (ALPL); alpha mannosidase II isozyme; alpha thalassemia/mental retardation syndrome X-linked (ATRX); alpha-2 macroglobulin; alpha-2-globin; alpha-2-macroglobulin receptor/lipoprotein receptor protein (A2MR/LRP); alpha-polypeptide of N-acetyl-alpha-glucosaminidase (HEXA); alpha-spectrin; alpha-subunit of Gi2 a (GTP-binding signal transduction protein); aminin receptor 1 (67 kD); Ribosomal protein SA (LAMR1); aminolevulinate, delta-, dehydratase (ALAD); amino-terminal enhancer of split (AES); amino-terminal enhancer of split (AES); AMP deaminase isoform L (AMPD2); amphiphysin (Stiff-Mann syndrome with breast cancer 128 kD autoantigen) (AMPH); amphiphysin II; amphiphysin-like (AMPHL); AMY-1; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1); amyloid beta (A4) precursor-like protein 2 (APLP2); amyloid precursor protein (APP); annexin I (lipocortin I) (ANX1); annexin II; annexin II (lipocortin II; calpactin I, heavy polypeptide) (ANX2); annexin IV (placental anticoagulant protein II) (ANX4); annexin V (endonexin II) (ANX5); annexin V (endonexin II) (ANXV); annexin VI (p68) (ANX6); annexin VII (synexin) (ANX7); antigen identified by monoclonal antibodies 12E7, F21 and 013 (MIC2); antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43 (MDU1); anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) (KIAA0106); APEX nuclease (multifunctional DNA repair enzyme) (APEX); apoptosis inhibitor 1 (API1); apoptosis inhibitor 4 (survivin) (API4); apoptosis inhibitor 5 (API5); apoptosis specific protein (ASP); apoptotic protease activating factor (APAF1); aquaporin 3 (AQP3); aquaporin 9 (AQP9); arachidonate 12-lipoxygenase (ALOX12); arachidonate 5-lipoxygenase-activating protein (ALOX5AP); ariadne homolog (ARI); ariadne-2 (D. melanogaster) homolog (all-trans retinoic acid inducible RING finger) (ARI2); ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) (ACTR1A); ARP2 (actin-related protein 2, yeast) homolog (ACTR2); ARP2/3 protein compex subunit 34 (ARC34); Arp2/3 protein compex subunit p41 (ARC41); Arp2/3 protein complex subunit p16 (ARC16); Arp2/3 protein complex subunit p20 (ARC20); Arp2/3 protein complex subunit P21 (ARC21); ARP3 (actin-related protein 3, yeast) homolog (ACTR3); arrestin, beta 2 (ARRB2); arsA (bacterial) arsenite transporter, ATP-binding, homolog 1 (ASNA1); aryl hydrocarbon receptor nuclear translocator-like (ARNTL); aryl hydrocarbon receptor-interacting protein (AIP); arylsulfatase A (ARSA); asialoglycoprotein receptor 2 (ASGR2); asparaginyl-tRNA synthetase (NARS); aspartyl-tRNA synthetase (DARS); ataxia telangiectasia mutated (includes complementation groups A, C and D) (ATM); ataxin-2-like protein A2LP (A2LG); ATF6; ATP synthase (F1-ATPase) alpha subunit, mitochondrial; ATP synthase beta subunit gene; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1 (ATP5F1); ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1 (ATP5G1); ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle (ATP5A1); ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (ATP5B); ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 (ATP5C1); ATP synthase, H+ transporting, mitochondrial F1F0, subunit g (ATP5JG); ATP/GTP-binding protein (HEAB); ATPase, Ca++ transporting, ubiquitous (ATP2A3); ATPase, H+ transporting, lysosomal (vacuolar proton pump) 21 kD (ATP6F); ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31 kD (ATP6E); ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42 kD; Vacuolar proton-ATPase, subunit C; V-ATPase, subunit C (ATP6D); ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha polypeptide, 70 kD, isoform 1 (ATP6A1); ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 56/58 kD, isoform 2 (ATP6B2); ATPase, H+transporting, lysosomal (vacuolar proton pump), member J (ATP6J); ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1 (ATP6S1); ATP-binding cassette 50 (TNF-alpha stimulated) (ABC50); ATP-binding cassette protein M-ABC1 (mitochondrial); ATP-dependent RNA helicase; atrial natriuretic factor (ANF); autoantigen (Hs.75528); autoantigen (Hs.75682); autoantigen La/SS-B; axin (AXIN1); axonemal dynein heavy chain (DNAH17); basement membrane-induced gene (ICB1); basic leucine zipper nuclear factor 1 (JEM-1) (BLZF1); basic transcription factor 3 (BTF3); basigin (BSG); BC-2; B-cell CLL/lymphoma 6 (zinc finger protein 51) (BCL6); B-cell translocation gene 1, anti-proliferative (BTG); BCL2/adenovirus E1B 19 kD-interacting protein 2 (BNIP2); BCL2/adenovirus E1B 19 kD-interacting protein 3-like (BNIP3L); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) (BECN1); beta-1,2-N-acetylglucosaminyltransferase II (MGAT2); beta-2-microglobulin (B2M); beta-hexosaminidase alpha chain (HEXA); beta-tubulin; BING4; biphenyl hydrolase-like (serine hydrolase) (BPHL); bone marrow stromal cell antigen 1 (BST1); box-dependent myc-interacting protein isoform BIN1-10 (BIN1); brain my047 protein; branched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease) (BCKDHA); BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (BAP1); breakpoint cluster region protein, uterine leiomyoma, 1; barrier to autointegration factor (BCRP1); breakpoint cluster region protein, uterine leiomyoma, 2 (BCRP2); bromodomain-containing protein, 140 kD (peregrin) (BR140); Bruton's agammaglobulinemia tyrosine kinase (Btk); Bruton's tyrosine kinase (BTK); BS4; BTG2 (BTG2); BTK region clone ftp; BTK region clone ftp-3; BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog (BUB3); butyrate response factor 1 (EGF-response factor 1) (BRF1); butyrophilin (BTF1); butyrophilin like receptor; CAG repeat containing (CTG4A); CAGH32; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma (CAMK2G); calcium/calmodulin-dependent protein kinase kinase (KIAA0787); calmodulin 1 (phosphorylase kinase, delta) (CALM1); calnexin (CANX); calpain, large polypeptide L1 (CAPN1); calpain, large polypeptide L2 (CANP2); calpain, small polypeptide (CAPN4); calpastatin (CAST); Calponin 2; calponin 2 (CNN2); calumenin (CALU); cAMP response element-binding protein CRE-Bpa (H_GS165L15.1); cAMP-dependent protein kinase type II (Ht31); canicular multispecific organic anion transporter (CMOAT2); capping protein (actin filament) muscle Z-line, alpha 1 (CAPZA1); capping protein (actin filament) muscle Z-line, alpha 2 (CAPZA2); capping protein (actin filament) muscle Z-line, beta (CAPZB); capping protein (actin filament), gelsolin-like (CAPG); carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD); carbonic anhydrase V, mitochondrial (CA5); carboxypeptidase D (CPD); cardiac beta-myosin heavy chain; carnitine/acylcarnitine translocase (CACT); Cas-Br-M (murine) ecotropic retroviral transforming sequence (cb1); casein kinase 1, alpha 1 (CSNK1A1); casein kinase 2, alpha 1 polypeptide (CSNK2A1); casein kinase I gamma 3L (CSNK1G3L); CASP8 and FADD-like apoptosis regulator (CFLAR); caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) (CASP1); caspase 10, apoptosis-related cysteine protease (CASP10); caspase 3, apoptosis-related cysteine protease (CASP3); caspase 4, apoptosis-related cysteine protease (CASP4); caspase 5, apoptosis-related cysteine protease (CASP5); caspase 8, apoptosis-related cysteine protease (CASP8); caspase 9, apoptosis-related cysteine protease (CASP9); catalase (CAT); catechol-O-methyltransferase (COMT); catenin (cadherin-associated protein), alpha 1 (102 kD) (CTNNA1); cathelicidin antimicrobial peptide (CAMP); cathepsin B (CTSB); cathepsin C (CTSC); cathepsin D (lysosomal aspartyl protease) (CTSD); cathepsin E (CTSE); cathepsin G (CTSG); cathepsin S (CTSS); cathepsin W (lymphopain) (CTSW); CCAAT/enhancer binding protein (C/EBP), alpha (CEBPA); CCAAT/enhancer binding protein (C/EBP), delta (CEBPB); CCAAT-box-binding transcription factor (CBF2); CD14 antigen (CD14); CD1C antigen, c polypeptide (CD1C); CD2 antigen (cytoplasmic tail)-binding protein 2 (CD2BP2); CD2 antigen (p50), sheep red blood cell receptor (CD2); CD2 cytoplasmic tail-binding protein 1 (CD2BP1); CD20 antigen (CD20); CD20 receptor (S7); CD22 antigen (CD22); CD24signal transducer; CD33 antigen (gp67) (CD33); CD33 antigen-like 2; CD36 antigen (collagen type I receptor, thrombospondin receptor) (CD36); CD37 antigen (CD37); CD38 alt; CD39 antigen (CD39); CD3D antigen, delta polypeptide (TiT3 complex) (CD3D); CD3E antigen, epsilon polypeptide (TiT3 complex) (CD3E); CD3G antigen, gamma polypeptide (TiT3 complex) (CD3G); CD3Z antigen, zeta polypeptide (TiT3 complex) (CD3Z); CD3-zeta (clone pBS NK1); CD4 antigen (p55) (CD4); CD44 antigen (homing function and Indian blood group system (CD44); CD48 antigen (B-cell membrane protein) (CD48); CD53 antigen (CD53); CD63 antigen (melanoma 1 antigen) (CD63); CD68 antigen (CD68); CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (CD74); CD79A antigen (immunoglobulin-associated alpha) (CD79A); CD79B antigen (immunoglobulin-associated beta) (CD79B); CD8 antigen, alpha polypeptide (p32) (CD8A); CD8 antigen, beta polypeptide 1 (p37) (CD8B1); CD81 antigen (target of antiproliferative antibody 1 (CD81); CD84 antigen (leukocyte antigen) (CD84); CD86 antigen; CD9 antigen (p24) (CD9); CD97 antigen (CD97); CDC23 (cell division cycle 23, yeast, homolog) (CDC23); CDC37 homolog; Cdc42 effector protein 3 (CEP3); CDC-like kinase (CLK); CDC-like kinase 2 (CLK2); CDW52 antigen (CAMPATH-1 antigen) (CDW52); cell cycle progression restoration 8 protein(CPR8); cell division cycle 10 (homologous to CDC10 of S. cerevisiae) (CDC10); cell division cycle 20, S.cerevisiae homolog (CDC20); cell division cycle 25B (CDC25B); cell division cycle 42 (GTP-binding protein, 25 kD) (CDC42); centromere protein B (80 kD) (CENPB); cep250 centrosome associated protein; ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) (CLN2); CGI-19 protein; chaperonin containing TCP1, subunit 3 (gamma) (CCT3); chaperonin containing TCP1, subunit 4 (delta) (CCT4); chaperonin containing TCP1, subunit 6A (zeta 1) (CCT6A); chaperonin containing TCP1, subunit 7 (eta) (CCT7); Chediak-Higashi syndrome 1 (CHS1); chemokine (C-C motif) receptor 2 (CCR2); chemokine (C-C motif) receptor 7 (CCR7); chemokine (C-X3-C) receptor 1 (CX3CR1); chemokine (C-X-C motif), receptor 4 (fusin) (CXCR4); chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1); chitinase 3-like 2 (CHI3L2); chloride channel 6 (CLCN6); Chloride intracellular channel 1 (CLIC1); chondroitin sulfate proteoglycan 2 (versican) (CSPG2); chondroitin sulfate proteoglycan core protein; chromodomain helicase DNA binding protein 1 (CHD1); chromodomain helicase DNA binding protein 1-like (CHD1L); chromodomain helicase DNA binding protein 2 (CHD2); chromodomain helicase DNA binding protein 3 (CHD3); chromodomain helicase DNA binding protein 4 (CHD4); chromosome 1 open reading frame 7 (C1ORF7); chromosome 1 specific transcript KIAA0493; chromosome 17 open reading frame 1B (C17ORF1B); chromosome 4 open reading frame 1 (C4ORF1); chromosome condensation 1-like (CHC1L); chromosome X open reading frame 5 (CXORF5); chromosome-associated polypeptide C(CAP-C); cig42; cig5; citrate synthase (CS); class I major histocompatibility antigen (HLA-Cw3); clathrin assembly protein lymphoid myeloid leukemia (CALM); clathrin heavy chain; clathrin, heavy polypeptide-like 2 (CLTCL2); clathrin-associated/assembly/adaptor protein, medium 1 (CLAPM1); cleavage stimulation factor, 3′ pre-RNA, subunit 3, 77 kD (CSTF3); clk3; clone 23815 (Hs.82845); clone 24592 mRNA sequence; Clq/MBL/SPA receptor ClqR(p); clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) (CLU); CMP-sialic acid transporter (CMPST); CMRF35; c-myc oncogene containing coxIII; coagulation factor II (thrombin) receptor (F2R); coagulation factor V (proaccelerin, labile factor) (F5); coagulation factor XIII a subunit; coagulation factor XIII, A1 polypeptide (F13A1); coated vesicle membrane protein (RNP24); coatomer protein complex, subunit alpha (COPA); Cofilin 1 (non-muscle) (CFL1); cold inducible RNA-binding protein (CIRBP); cold shock domain protein A (CSDA); collagen, type IX, alpha 2 (COL9A2); colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog (CSF1R); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (CSF2RB); colony stimulating factor 3 receptor (granulocyte) (CSF3R); complement component 5 receptor 1 (C5a ligand) (C5R1); conserved gene amplified in osteosarcoma (OS4); COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 3 (COPS3); COP9 homolog (HCOP9); COPII protein, homolog of s. cerevisiae SEC23p (SEC23A); copine I (CPNE1); coproporphyrinogen oxidase (coproporphyria, harderoporphyria) (CPO); core-binding factor, beta subunit (CBFB); coronin; cot (cancer Osaka thyroid) oncogene (COT); cryptochrome 1 (photolyase-like) (CRY1); CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 (CTDP1); C-terminal binding protein 1 (CTBP1); C-terminal binding protein 2 (CTBP2); CUG triplet repeat, RNA-binding protein 1 (CUGBP1); cullin 1 (CUL1); cullin 3 (CUL3); cut (Drosophila)-like 1 (CCAAT displacement protein) (CUTL1); cyclin D2 (CCND2); cyclin D3 (CCND3); cyclin G1 (CNNG1); cyclin I; cyclin T2 (CNNT2); cyclin-dependent kinase 2 (CDK2); cyclin-dependent kinase inhibitor (p27Kipl); cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A); cystatin B (stefin B) (CSTB); cysteine and glycine-rich protein 3 (cardiac LIM protein) (CSRP3); cytidine deaminase (CDA); cytochrome b(-245) beta chain N-terminal region (X-linked granulomatous disease gene); cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB); cytochrome c oxidase subunit IV (COX4); cytochrome c oxidase subunit Vb (COX5B); cytochrome c oxidase subunit VII-related protein (COX7RP); cytokine suppressive anti-inflammatory drug binding protein 1 (p38 MAP kinase) (CSBP1); Cytoplasmic antiproteinase=38 kda intracellular serine proteinase inhibitor; cytotoxic granule-associated RNA-binding protein p40-TIA-1; D123 (D123); D2-2; D38; damage-specific DNA binding protein 1 (127 kD) (DDB1); DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1 (DDXBP1); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide (72 KD) (P72); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1 (DDX1); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 15 (DDX15); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16 (DDX16); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 (DDX3); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68 kD) (DDX5); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54 kD) (DDX6); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 8 (RNA helicase, 54 kD) (DDX8); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9 (RNA helicase A, nuclear DNA helicase II; leukophysin) (DDX9); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome (DBY); Death associated protein 3 (DAP3); death effector domain-containing protein (DEDD); death-associated protein 6 (DAXX); dedicator of cyto-kinesis 2 (DOCK2); defender against cell death 1 (DAD1); Defensin, alpha 1, myeloid-related sequence (DEFA1); DEK gene (D6S231E); delta sleep inducing peptide, immunoreactor (DSIPI); dendritic cell protein (GA17); deoxycytidine kinase (DCK); deoxyribonuclease II, lysosomal (DNASE2); DGS-I; diacylglycerol kinase; diacylglycerol kinase alpha (DAGK1) (clone 24); diaphanous (Drosophila, homolog) 1 (DIAPH1); diaphorase (NADH) (cytochrome b-5reductase) (DIA1); differentiated Embryo Chondrocyte expressed gene 1 (DEC1); differentiation antigen CD20; DiGeorge syndrome critical region gene 2 (DGCR2); dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) (DLD); dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (DLAT); dihydropyrimidinase-like 2 (DPYSL2); dinG gene; diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2 (DPH2L2); DJ-1 protein; Dmx-like 1 (DMXL1); DNA (cytosine-5-)-methyltransferase 1 (DNMT1); DNA fragmentation factor, 40 kD, beta subunit (DFFB); DNA fragmentation factor, 45 kD, alpha subunit (DFFA); DNA mismatch repair protein (hMLH1); DNA segment on chromosome X (unique) 648 expressed sequence; DNA segment, single copy probe LNS-CAI/LNS-CAII (deleted in polyposis (D5S346); DnaJ protein; docking protein 2, 56 kD (DOK2); dolichyl-diphosphooligosaccharide-protein glycosyltransferase (DDOST); dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit (DPM1); down-regulated by activation (immunoglobulin superfamily) (DORA); D-type cyclin-interacting protein 1 (DIP1); dual specificity phosphatase 1 (DUSP1); dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) (dusp11); dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (DUSP3); dual specificity phosphatase 6 (DUSP6); dynactin 1 (p150, Glued (Drosophila) homolog) (DYTN1); dynamin 2 (DNM2); dynein, cytoplasmic, light intermediate polypeptide 2 (DNCLI2); dyskeratosis congenita 1, dyskerin (DKC1); dystonia 1, torsion (autosomal dominant) (DYT1); dystrobrevin, beta (DTNB); dystrophia myotonica-containing WD repeat motif (DMWD); dystrophia myotonica-protein kinase (DMPK); E1B-55 kDa-associated protein; E2F transcription factor 3 (E2F3); E2F transcription factor 4, p107/p130-binding (E2F4); E2F transcription factor 5, p130-binding (E2F5); E74-like factor 1 (ets domain transcription factor) (ELF1); E74-like factor 4 (ets domain transcription factor) (ELF4); early development regulator 2 (homolog of polyhomeotic 2) (EDR2); EBV induced G-protein coupled receptor (EBI2); ecotropic viral integration site 2B (EVI2B); ectin, galactoside-binding, soluble, 1 (galectin 1) (LGALS1); EGF-like-domain, multiple 4 (EGFL4); eIF-2-associated p67 homolog; elav-type RNA-binding protein (ETR-3); electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) (ETFA); ELK3, ETS-domain protein (SRF accessory protein 2) (ELK3); elongation factor 1-beta; elongation factor Ts (mitochondrial protein); elongation factor Tu-nuclear encoded mitochondrial; eMDC II protein; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate) (EMS1); endogenous retroviral element HC2; endosulfine alpha (ENSA); endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 (EDG1); eendothelial monocyte-activating polypeptide (EMAPII); enolase 1, (alpha) (ENO1); enolase 2, (gamma, neuronal) (ENO2); enolase-alpha; enoyl Coenzyme A hydratase 1, peroxisomal (ECH1); enoyl Coenzyme A hydratase, short chain, 1, mitochondrial (ECHS1); epidermal growth factor receptor pathway substrate 15 (EPS15); epithelial membrane protein 3 (EM[P3); Epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1); ERF-2; Erp28 protein; erythrocyte membrane protein; erythroleukemic cells K562; EST (Hs.189509); estrogen receptor-related protein (hERRa1); ET binding factor 1 (SBF1); ets domain protein ERF; eukaryotic translation elongation factor 1 alpha 1 (EEF1A1); eukaryotic translation elongation factor 1 beta 2 (EEF1B2); eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) (EEF1D); eukaryotic translation elongation factor 1 gamma (EEF1G); eukaryotic translation elongation factor 2 (EEF2); eukaryotic translation initiation factor 2, subunit 1 (alpha, 35 kD) (EIF2S1); eukaryotic translation initiation factor 2, subunit 2 (beta, 38 kD) (EIF2S2); eukaryotic translation initiation factor 2, subunit 3 (gamma, 52 kD) (EIF2S3); eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170 kD) (EIF3S10); eukaryotic translation initiation factor 3, subunit 2 (beta, 36 kD) (EIF3S2); eukaryotic translation initiation factor 3, subunit 3 (gamma, 40 kD) (EIF3S3); eukaryotic translation initiation factor 3, subunit 4 (delta, 44 kD) (EIF3S4); eukaryotic translation initiation factor 3, subunit 6 (48 kD) (EIF3S6); eukaryotic translation initiation factor 3, subunit 6 (EIF3S6); eukaryotic translation initiation factor 3, subunit 7 (zeta, 66/67 kD) (EIF3S7); eukaryotic translation initiation factor 3, subunit 8, 110KD (EIF3S8); eukaryotic translation initiation factor 4 gamma, 1 (EIF4G); eukaryotic translation initiation factor 4 gamma, 1 (EIF4G1); eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2); eukaryotic translation initiation factor 4 gamma, 2 (EIFG2); eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1); eukaryotic translation initiation factor 4A, isoform 2 (EIF4A2); eukaryotic translation initiation factor 4B (EIF4B); Eukaryotic translation initiation factor 4E binding protein 2 (EIF4EBP2); eukaryotic translation initiation factor 5 (EIF5); eukaryotic translation termination factor 1 (ETF1); EV12 protein; Ewing sarcoma breakpoint region 1 (EWSR1); EWS/FLI1 activated transcript 2 homolog (EAT-2); EWS-E1A-F chimeric protein; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1); excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)) (ERCC5); exostoses (multiple)-like 3 (EXTL3); F11; F1-ATPase beta subunit (F-1 beta); Fanconi anaemia group A; Fanconi anemia, complementation group A (FANCA); far upstream element (FUSE) binding protein 1 (FUBP1); farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase,dimethylallyltranstransferase, geranyltranstransferase) (FDPS); farnesyl-diphosphate farnesyltransferase 1 (FDFT1); farnesyltransferase, CAAX box, beta (FNTB); Fas-ligand associated factor 1; fatty-acid-Coenzyme A ligase, long-chain 1 (FACL1); Fc fragment of IgA, receptor for (FCAR); Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide (FCER1G); Fc fragment of IgE, low affinity II, receptor for (CD23A) (FCER2); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32) (FCGR2A); Fc fragment of IgG, low affinity IIIa, receptor for (CD16) (FCGR3A); Fc fragment of IgG, receptor, transporter, alpha (FCGRT); fc-fgr; Fc-gamma-receptorIIIB (FCGR3B); feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog(FES) c-fes/fps); female sterile homeotic-related gene 1 (mouse homolog) (FSRG1); ferritin L-chain; ferritin, heavy polypeptide 1 (FTH1); fetal Alzheimer antigen (FALZ); fetal Ig heavy chain variable region; fibrillarin (FBL); fibrinogen-like protein 2 (T49); ficolin (collagen/fibrinogen domain-containing) 1 (FCN1); filamin A, alpha (actin-binding protein-280) (FLNA); filamin B, beta (actin-binding protein-278) (FLNB); Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 (FAU); FK-506 binding protein; FK506-binding protein 1A (12 kD) (FKBP1A); FK506-binding protein 1B (12.6 kD) (FKBP1B); FK506-binding protein 5 (FKBP5); Flightless I (Drosophila) homolog (FLII); FLN29 (FLN29); flotillin 2 (FLOT2); folate receptor 2 (fetal) (FOLR2); forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1 (FKHRL1); Formyl peptide receptor 1 (FPR1); formyl peptide receptor-like 1 (FPRL1); fragile X mental retardation 1 (FMR1); fragile X mental retardation, autosomal homolog 1 (FXR1); Friend leukemia virus integration 1 (FLI1); fructose-bisphosphatase 1 (FBP1); FSHD-associated repeat DNA, proximal region; fucose-1-phosphate guanylyltransferase (FPGT); full length insert cDNA clone ZA78A09; full length insert cDNA YPO7G10; fumarate hydratase (FH); FYN-binding protein (FYB-120/130) (FYB); G protein beta subunit-like protein 12.3; G protein-coupled receptor kinase 6 (GPRK6); G1 to S phase transition 1 (GSPT1); GA-binding protein transcription factor, beta subunit 2 (47 kD) (GABPB2); galactose-1-phosphate uridylyltransferase (GALT); galactosidase, beta 1 (GLB1); galectin-9 isoform; gamma2-adaptin (G2AD); gamma-actin; gamma-aminobutyric acid (GABA) B receptor 1 (GABBR1); GATA-binding protein 2 (GATA2); GATA-binding protein 3 (GATA3); GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1 (GCN5L1); GDP dissociation inhibitor 1 (GDI1); GDP dissociation inhibitor 2 (GCl2); GDS-related protein (HKE1.5); gelsolin (amyloidosis, Finnish type) (GSN); general transcription factor II, I (GTF2I); general transcription factor II, i, pseudogene 1 (GTF2IP1); general transcription factor IIF, polypeptide 1 (74 kD subunit) (GTF2F1); general transcription factor IIH, polypeptide 3 (34 kD subunit) (GTF2H3); general transcription factor IIH, polypeptide 4 (52 kD subunit) (GTF2H4); general transcription factor IIIA (GTF3A); general transcription factor IIIC, polypeptide 1 (alpha subunit, 220 kD) (GTF3C1); general transcription factor IIIC, polypeptide 2 (beta subunit, 110 kD) (GTF3C2); germline immunoglobulin heavy chain (IGHV@); germline immunoglobulin heavy chain, variable region; germline immunoglobulin heavy chain, variable region, (21-2); GLE1 (yeast homolog)-like, RNA export mediator (GLE1L); glia maturation factor, beta (GMFB); glioma-associated oncogene homolog (zinc finger protein) (GLI); globin, alpha 2; glucocorticoid receptor (GRL); glucos phosphate isomerase (CONTAINS LARGE REPEAT); glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) (GNS); glucose transporter-like protein-III (GLUT3); glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) (GAA); glucosidase, beta; acid (includes glucosylceramidase) (GBA); glutamate dehydrogenase 1 (GLUD1); glutamate-ammonia ligase (glutamine synthase) (GLUL); glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), catalytic (72.8 kD) (GLCLC); glutamine cyclotransferase; glutamine-fructose-6-phosphate transaminase 1 (GFPT1); glutaminyl-tRNA synthetase; glutaminyl-tRNA synthetase (QARS); glutamyl-prolyl-tRNA synthetase (EPRS); glutathione peroxidase 1 (GPX1); glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4); glutathione S-transferase pi (GSTP1); glutathione S-transferase subunit 13 homolog; glyceraldehyde-3-phosphate dehydrogenase (GAPD); glycogenin (GYG); glycophorin C (Gerbich blood group) (GYPC); glycoprotein M6B (GPM6B); glycyl-tRNA synthetase (GARS); glyoxalase I (lactoyl glutathione lyase) (GLYI); golgi autoantigen, golgin subfamily a, 1 (GOLGA1); golgi autoantigen, golgin subfamily a, 4 (GOLGA4); golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 (GOLGB1); gp25L2 protein; grancalcin; granulin (GRN); Granulysin (NKG5); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) (GZMA); GRB2-related adaptor protein (GRAP); Grb2-related adaptor protein 2 (GRAP2); GRO1 oncogene (melanoma growth stimulating activity, alpha) (GRO1); growth arrest and DNA-damage-inducible gene (GADD153); growth arrest-specific 7 (GAS7); growth factor receptor-bound protein 2 (GRB2); GS1 (protein of unknown function); GS3955; GTP binding protein 1 (GTPBP1); GTPase activating protein-like (GAPL); Gu protein (GURDB); guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 (GNAI2); guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 (GNAI3); guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1); guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (GNAT2); guanine nucleotide binding protein (G protein), beta 5 (GNB5); guanine nucleotide binding protein (G protein), beta polypeptide 1 (GNB1); guanine nucleotide binding protein (G protein), q polypeptide (GNAQ); guanine nucleotide binding protein-like 1 (GNL1); guanine nucleotide exchange factor; guanine nucleotide regulatory factor (LFP40); GUANINE-MONOPHOSPHATE SYNTHETASE (GMPS); guanosine-diphosphatase like protein; guanylate binding protein 1, interferon-inducible, 67 kD (GBP1); guanylate binding protein 2, interferon-inducible (GBP2); H2A histone family, member C (H2AFC); H2A histone family, member Y (H2AY); H2B histone family, member L (H2BFL); h2-calponin; H-2K binding factor-2; H3 histone family, member K (H3FK); H3 histone, family 3A (H3F3A); H3 histone, family 3B (H3.3B) (H3F3B); hbc647; heat shock 27 kD protein 1 (HSPB1); heat shock 40 kD protein 1 (HSPF1); heat shock 60 kD protein 1 (chaperonin) (HSPD1); heat shock 70 kD protein 1 (HSPA1A); heat shock 70 kD protein 5 (glucose-regulated protein, 78 kD) (HSPA5); heat shock 70 kD protein 6 (HSP70B′) (HSPA6); heat shock 70 kD protein 9B (mortalin-2) (HSPA9B); heat shock factor binding protein 1 (HSBP1); heat shock protein 90; heat shock protein, DNAJ-like 2 (HSJ2); Hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1 (HERC1); hect domain and RLD 2 (HERC2); helicase-like protein (HLP); helix-loop-helix protein HE47 (E2A); hematopoietic cell-specific Lyn substrate 1 (HCLS1); heme oxygenase (decycling) 1 (HMOX1); hemoglobin beta (beta globin); hemoglobin, alpha 1 (HBA1); hemoglobin, beta (HBB); emokine (C-X-C motif), receptor 4 (fusin) (CXCR4); hemopoietic cell kinase (HCK); hepatitis C-associated microtubular aggregate protein p44; hepatoma-derived growth factor; Hermansky-Pudlak syndrome (HPS); heterogeneous nuclear ribonucleoprotein (C1/C2) (HNRPC); heterogeneous nuclear ribonucleoprotein A/B (HNRPAB); heterogeneous nuclear ribonucleoprotein A1 (HNRPA1); heterogeneous nuclear ribonucleoprotein A2/B1 (HNRPA2B1); heterogeneous nuclear ribonucleoprotein D (hnRNP D); heterogeneous nuclear ribonucleoprotein D-like (HNRPDL); heterogeneous nuclear ribonucleoprotein F (HNRPF); heterogeneous nuclear ribonucleoprotein G (HNRPG); heterogeneous nuclear ribonucleoprotein H1 (H) (HNRPH1); heterogeneous nuclear ribonucleoprotein K (HNRPK); heterogeneous nuclear ribonucleoprotein R (HNRPR); heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (HNRPU); hexokinase 1 (HK1); hexokinase 2 (HK2); hexokinase 3 (HK3); hexosaminidase A (alpha polypeptide) (HEXA; HGMPO7I gene for olfactory receptor; High density lipoprotein binding protein (HDLBP); high-mobility group (nonhistone chromosomal) protein 1 (HMG1); High-mobility group (nonhistone chromosomal) protein 17 (HMG17); high-mobility group (nonhistone chromosomal) protein 2 (HMG2); high-mobility group (nonhistone chromosomal) protein isoforms I and Y; histidine ammonia-lyase (HAL); histidyl-tRNA synthetase (HARS); histocompatibility antigen (HLA-Cw3), class I; histone deacetylase 1 (HDAC); histone deacetylase 1 (HDAC1); histone deacetylase 5 (NY-CO-9); HK2 gene for hexokinase II; HL9 monocyte inhibitory receptor precursor; HLA class I heavy chain (HLA-Cw*1701); HLA class I locus C heavy chain; HLA class II SB 4-beta chain; HLA class III region containing NOTCH4 gene; HLA-A; HLA-A*7402; HLA-A11; HLA-B; HLA-B associated transcript-1 (D6S81E); HLA-B associated transcript-2 (D6S51E); HLA-B*1529; HLA-Bw72 antigen; HLA-C gene (HLA-Cw*0701 allele); HLA-Cw*0701; HLA-Cw*0801; HLA-Cw*1203; HLA-DR alpha-chain; HLA-F (leukocyte antigen F); HMG box containing protein 1; Hmob33; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1 (HRMT1L1); homeodomain-interacting protein kinase 3 (HIPK3); homolog of Drosophila past (PAST); homolog of yeast (S. cerevisiae) ufd2 (UFD2); HPV16 E1 protein binding protein; HRIHFB2157; hsc70 gene for 71 kd heat shock cognate protein; HSPC012; HSPC021; HsPex13p; htra2-beta-2; HU-K4; hunc18b2; HUNKI; huntingtin-interacting protein HYPA/FBP11 (HYPA); hVps41p (HVPS41); hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit (HADHA); hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit (HADHB); hydroxysteroid (17-beta) dehydrogenase 1 (HSD17B1); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A); Ia-associated invariant gamma-chain (clones lambda-y (1,2,3)); iduronate 2-sulfatase (Hunter syndrome) (IDS); Ig heavy chain variable region; Ig heavy chain variable region (VH4DJ) (clone T14.4); Ig heavy chain variable region (VH4DJ) (clone T22.18); Ig J chain; Ig kappa; IG kappa light chain variable region A20; Ig lambda light chain variable region (26-34ITIIIF120); Ig mu-chain VDJ4-region; Ig rearranged anti-myelin kappa-chain (V-J4-region, hybridoma AE6-5); Ig rearranged H-chain mRNA V-region; IgG Fc binding protein (FC(GAMMA)BP); IgG heavy chain variable region (vH26); IgM heavy chain (C mu, membrane exons); IkB kinase-beta (IKK-beta); IL-1 receptor type II; IL2-inducible T-cell kinase (ITK); immediate early protein (ETR101); immunogloblin light chain (lambda); Immunoglobulin (CD79A) binding protein 1 (IGBP1); immunoglobulin G Fc receptor IIIB; immunoglobulin gamma 3 (Gm marker) (IGHG3); immunoglobulin heavy chain (VI-3B); immunoglobulin heavy chain J region; immunoglobulin heavy chain J region, B1 haplotype; immunoglobulin heavy chain variable region (IGH) (clone 21u-48); immunoglobulin heavy chain variable region (IGH) (clone 23u-1); immunoglobulin heavy chain variable region V3-43(IGHV@); immunoglobulin heavy chain variable region V3-7 (IGHV@); immunoglobulin IgH heavy chain Fd fragment; immunoglobulin kappa light chain; immunoglobulin kappa light chain V-segment A27; immunoglobulin light chain; immunoglobulin light chain variable region (lambda IIIb subgroup) from IgM rheumatoid factor; immunoglobulin M heavy chain V region=anti-lipid A antibody; immunoglobulin mu (IGHM); immunoglobulin mu binding protein 2 (IGHMBP2); immunoglobulin superfamily, member 2 (IGSF2); imogen 38 (IMOGEN38); IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1); IMP (inosine monophosphate) dehydrogenase 2 (IMPDH2); inc finger protein 151 (pHZ-67) (ZNF151); inc finger protein, C2H2, rapidly turned over (ZNF20); inducible poly(A)-binding protein (IPABP); inducible protein (Hs.80313); inhibitor of DNA binding 2, dominant negative helix-loop-helix protein (ID2); inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP); inositol 1,3,4-trisphosphate 5/6-kinase; inositol 1,4,5 trisphosphate receptor type 1 (ITPR1); inositol 1,4,5-trisphosphate 3-kinase B (ITPKB); inositol monophosphatase; inositol polyphosphate-5-phosphatase, 145 kD (INPP5D); Ins(1,3,4,5)P4-binding protein; insulin (INS); insulin-like growth factor 2 receptor (IGF2R); integral membrane protein 1 (ITM1); integral membrane protein 2C (ITM2C); integral membrane protein Tmp21-I (p23); integrin beta 4 binding protein (ITGB4BP); integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) (ITGA2B); integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5); integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (ITGAL); integrin, alpha M (complement componentreceptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide) (ITGAM); integrin, alpha X (antigen CD11C (p150), alpha polypeptide) (ITGAX); integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2 MSK12) (ITGB1); integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) (ITGB2); integrin, beta 7 (ITGB7); Integrin-linked kinase (ILK); intercellular adhesion molecule 1 (CD54), human rhinovirus receptor (ICAM1); intercellular adhesion molecule 2 (ICAM2); intercellular adhesion molecule 3 (ICAM3); intercellular adhesion molecule 4, Landsteiner-Wiener blood group (ICAM4); Interferon consensus sequence binding protein 1 (ICSBP1); interferon regulatory factor 2 (IRF2); interferon regulatory factorl (IRF1); interferon regulatory factor5 (IRF5); interferon, gamma-inducible protein 16 (IFI16); interferon, gamma-inducible protein 30 (IFI30); interferon-induced protein 17 (IFI17); interferon-induced protein 54 (IF154); interferon-inducible (1-8D); interferon-inducible (1-8U); interferon-related developmental regulator 1 (IFRD1); interferon-stimulated transcription factor 3, gamma (48 kD) (ISGF3G); interleukin 1 receptor, type II (IL1R2); Interleukin 10 receptor, beta (I.10RB); interleukin 12 receptor, beta 1 (IL12RB1); interleukin 13 receptor, alpha 1 (IL13RA1); interleukin 16 (lymphocyte chemoattractant factor) (IL16); interleukin 18 receptor 1 (IL18R1); interleukin 2 receptor, beta (IL2RB); interleukin 2 receptor, gamma (severe combined immunodeficiency) (IL2RG); interleukin 4 receptor (IL4R); interleukin 6 receptor (IL6R); interleukin 6 signal transducer (gp130, oncostatin M receptor) (IL6ST); interleukin 7 receptor (IL7R); interleukin 8 (IL8); interleukin 8 receptor alpha (IL8RA); interleukin 8 receptor, beta (IL8RB); interleukin enhancer binding factor 2, 45 kD (ILF2); interleukin enhancer binding factor 3, 90 kD (ILF3); interleukin-1 receptor-associated kinase 1 (IRAK1); interleukin-10 receptor, alpha (IL10RA); interleukin-11 receptor, alpha (IL11RA); intestinal carboxylesterase; IQ motif containing GTPase activating protein 1 (IQGAP1); IQ motif containing GTPase activating protein 2 (IQGAP2); isocitrate dehydrogenase 1 (NADP+), soluble (IDH1); isocitrate dehydrogenase 2 (NADP+), mitochondrial (IDH2); isocitrate dehydrogenase 3 (NAD+) alpha (IDH3A); isocitrate dehydrogenase 3 (NAD+) gamma (IDH3G); isolate TzCCR5-179 CCR5 receptor (CCR5); isopentenyl-diphosphate delta isomerase (IDI1); Janus kinase 1 (a protein tyrosine kinase) (JAK1); Janus kinase 2 (a protein tyrosine kinase) (JAK2); Jk-recombination signal binding protein (RBPJK); JM1 protein; jumonji (mouse) homolog (JMJ); jun D proto-oncogene (JUND); jun dimerization protein; junction plakoglobin (JUP); kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) (KAI1); karyopherin (importin) beta 1 (KPNB1); karyopherin (importin) beta 2 (KPNB2); karyopherin alpha 1 (importin alpha 5) (KPNA1); karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (DPNA2); karyopherin alpha 3 (importin alpha 4) (KPNA3); karyopherin alpha 4 (KPNA4); Katanin (80 kDa) (KAT); KE03 protein; Keratin 8 (KRT8); ketohexokinase (fructokinase) (KHK); KIAA0002 (KIAA0002); KIAA0005 (KIAA0005); KIAA0010 (KIAA0010); KIAA0016 (KIAA0016); KIAA0017 (KIAA0017); KIAA0022 (KIAA0022); KIAA0023 (KIAA0023); KIAA0024 (KIAA0024); KIAA0025 (KIAA0025); KIAA0026 (KIAA0026); KIAA0027; KIAA0032 (KIAA0032); KIAA0040 (KIAA0040); KIAA0050 (KIAA0050); KIAA0053 (KIAA0053); KIAA0057 (KIAA0057); KIAA0058 (KIAA0058); KIAA0063 (KIAA0063); KIAA0064 (KIAA0064); KIAA0066; KIAA0068; KIAA0073; KIAA0081; ; KIAA0084; KIAA0085; KIAA0088; KIAA0090; KIAA0092 (KIAA0092); KIAA0094; KIAA0095 (KIAA0095); KIAA0096; KIAA0097 (KIAA0097); KIAA0099 (KIAA0099); KIAA0102 (KIAA0102); KIAA0105; KIAA0121 (KIAA0121); KIAA0123; KIAA0128; KIAA0129 (KIAA0129); KIAA0130 (KIAA0130); KIAA0136; KIAA0137 (KIAA0137); KIAA0140 (KIAA0140); KIAA0141 (KIAA0141); KIAA0144 (KIAA0144); KIAA0146; KIAA0148 (KIAA0148); KIAA0154; KIAA0156; KIAA0160; KIAA0161 (KIAA0161); KIAA0164 (KIAA0164); KIAA0167 (KIAA0167); KIAA0168 (KIAA0168); KIAA0169; KIAA0171 (KIAA0171); KIAA0174 (KIAA0174); KIAA0179; KIAA0181; KIAA0183; KIAA0184; KIAA0193 (KIAA0193); KIAA0200 (KIAA0200); KIAA0210 (KIAA0210); KIAA0217; KIAA0219; KIAA0222 (KIAA0222); KIAA0223; KIAA0229; KIAA0232 (KIAA0232); KIAA0233 (KIAA0233); KIAA0235; KIAA0239; KIAA0240; KIAA0242; KIAA0248; KIAA0249 (KIAA0249); KIAA0253; KIAA0254 (KIAA0254); KIAA0255(KIAA0255); KIAA0262 (KIAA0262); KIAA0263 (KIAA0263); KIAA0264; KIAA0268; KIAA0275 (KIAA0275); KIAA0304 (KIAA0304); KIAA0308; KIAA0310 (KIAA0310); KIAA0315 (KIAA0315); KIAA0329 (KIAA0329); KIAA0330; KIAA0332; KIAA0333; KIAA0336 (KIAA0336); KIAA0342 (KIAA0342); KIAA0344 (KIAA0344); KIAA0354 (KIAA0354); KIAA0365 (KIAA0365); KIAA0370; KIAA0372 (KIAA0372); KIAA0373 (KIAA0373); KIAA0375 (KIAA0375); KIAA0377 (KIAA0377); KIAA0379; KIAA0380 (KIAA0380); KIAA0382 (KIAA0382); KIAA0383; KIAA0386 (KIAA0386); KIAA0392; KIAA0397 (KIAA0397); KIAA0403; KIAA0404; KIAA0409; KIAA0421; KIAA0428 (KIAA0428); KIAA0429 (KIAA0429); KIAA0430 (KIAA0430); KIAA0432 (KIAA0432); KIAA0435 (KIAA0435); KIAA0438 (KIAA0438); KIAA0447 (KIAA0447); KIAA0449; KIAA0456; KIAA0458 (KIAA0458); KIAA0462; KIAA0465; KIAA0476 (KIAA0476); KIAA0489; KIAA0494 (KIAA0494); KIAA0515; KIAA0521; KIAA0525; KIAA0530; KIAA0532; KIAA0537 (KIAA0537); KIAA0540; KIAA0543; KIAA0544; KIAA0549; KIAA0551; KIAA0554; KIAA0561; KIAA0562 (KIAA0562); KIAA0563 (KIAA0563); KIAA0569 (KIAA0569); KIAA0571 (KIAA0571); KIAA0573; KIAA0576; KIAA0580; KIAA0584; KIAA0592; KIAA0596; KIAA0598 (KIAA0598); KIAA0608; KIAA0614; KIAA0615 (KIAA0615); KIAA0621; KIAA0648; KIAA0652 (KIAA0652); KIAA0668; KIAA0669; KIAA0671 (KIAA0671); KIAA0675 (KIAA0675); KIAA0676; KIAA0677 (KIAA0677); KIAA0678; KIAA0679; KIAA0680 (KIAA0680); KIAA0692; KIAA0697; KIAA0699; KIAA0700; KIAA0737 (KIAA0737); KIAA0748 (KIAA0748); KIAA0763 (KIAA0763); KIAA0769 (KIAA0769); KIAA0782; KIAA0796; KIAA0798 (KIAA0798); KIAA0823; KIAA0854; KIAA0856; KIAA0860; KIAA0862; KIAA0873; KIAA0892; KIAA0906; KIAA0991; killer cell lectin-like receptor subfamily B, member 1 (KLRB1); killer cell lectin-like receptor subfamily C, member 4 (KLRC4); kinectin 1 (kinesin receptor) (KTN1); kinesin family member 5B (KIF5B); kinesin-like DNA binding protein; Kruppel related gene (clone pHKR1RS); Kruppel-like zinc finger protein Zf9; kruppel-type zinc finger protein, ZK1; L apoferritin; lactate dehydrogenase A (LDHA); lactate dehydrogenase B (LDHB); lactotransferrin (LTF); laminin receptor 1 (67 kD); Ribosomal protein SA (LAMR1); laminin receptor homolog {3′ region}; laminin, gamma 1 (formerly LAMB2) (LAMC1); latent transforming growth factor beta binding protein 1 (LTBP1); LDLC; lectin, galactoside-binding, soluble, 2 (galectin 2) (LGALS2); lectin, galactoside-binding, soluble, 3 binding protein (galectin 6 binding protein) (LGALS3BP); leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1); leucocyte immunoglobulin-like receptor-5 (LIR-5); leucocyte immunoglobulin-like receptor-6a (LIR-6); leucocyte immunoglobulin-like receptor-7 (LIR-7); leukemia virus receptor 1 (GLVR1); leukocyte adhesion protein p150,95 alpha subunit; leukocyte antigen, HLA-A2; leukocyte immunoglobulin-like receptor (MIR-10); leukocyte tyrosine kinase (LTK); leukocyte-associated Ig-like receptor 1 (LIAR1); leukotriene A4 hydrolase (LTA4H); leupaxin (LDPL); ligase I, DNA, ATP-dependent (LIG1); LIM and SH3 protein 1 (LASP1); LIM domain kinase 2 (LIMK2); Line-1 repeat mRNA with 2 open reading frames; Line-1 repeat with 2 open reading frames; lipase A, lysosomal acid, cholesterol esterase (Wolman disease) (LIPA); lipase, hormone-sensitive (LIPE); LMP7; Lon protease-like protein (LONP); low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) (LRP1); low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) (LRPAP1); low-affinity Fc-gamma receptor IIA; LPS-induced TNF-alpha factor (PIG7); Lst-1; L-type amino acid transporter subunit LAT1; lung resistance-related protein (LRP); Lymphocyte antigen 75 (LY75); lymphocyte antigen 9 (LY9); lymphocyte antigen HLA-B*4402 and HLA-B*5101; lymphocyte cytosolic protein 1 (L-plastin) (LCP1); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kD) (LCP2); lymphocyte glycoprotein T1/Leu-1; lymphocyte-specific protein 1 (LSP1); lymphocyte-specific protein tyrosine kinase (LCK); lymphoid phosphatase LyP1; lymphoid-restricted membrane protein (LRMP); lymphoid-specific SP100 homolog (LYSP100-A); lymphoma proprotein convertase (LPC); lysosomal-associated membrane protein 1 (LAMP1); Lysosomal-associated membrane protein 2 (LAMP2); lysozyme (renal amyloidosis) (LYZ); lysyl-tRNA synthetase (KARS); M phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) (MPP-10); M1-type and M2-type pyruvate kinase; m6A methyltransferase (MT-A70); mab-21 (C. elegans)-like 1 (MAB21L1); MacMarcks; macrophage-associated antigen (MM130); MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) (MEF2A); MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) (MEF2C); major histocompatibility complex class I beta chain (HLA-B); major histocompatibility complex, class I, A (HLA-A); major histocompatibility complex, class I, C (HAL-C); major histocompatibility complex, class I, E (HLA-E); major histocompatibility complex, class II, DM BETA (HLA-DMB); major histocompatibility complex, class II, DP beta 1 (HLA-DPB1); major histocompatibility complex, class II, DR beta 1 (HLA-DRB1); Major histocompatibility complex, class II, Y box-binding protein I; DNA-binding protein B (YB1); malate dehydrogenase 1, NAD (soluble) (mdh1); malate dehydrogenase 1, NAD (soluble) (MDH1); malonyl-CoA decarboxylase precursor; maltase-glucoamylase (mg); manic fringe (Drosophila) homolog (MFNG); mannose phosphate isomerase (MPI); mannose phosphate isomerase (mpi); mannose-6-phosphate receptor (cation dependent) (M6PR); mannose-P-dolichol utilitzation defect 1 (MPDU1); mannosidase, alpha B, lysosomal (MANB); mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT1); map 4q35 repeat region; MAP kinase-interacting serine/threonine kinase 1 (MKNK1); MAP/ERK kinase kinase 3 (MEKK3); MAP/ERK kinase kinase 5 (MEKK5); MAP/microtubule affinity-regulating kinase 3 (MARK3); Marenostrin protein; MASL1; MAX dimerization protein (MAD); MaxiK potassium channel beta subunit; MBP-2 for MHC binding protein 2; Meis (mouse) homolog 3 (MEIS3); melanoma-associated antigen p97 (melanotransferrin); membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) (MCP); membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) (M17S2); membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) (MME); membrane protein, palmitoylated 1 (55 kD) (MPP1); meningioma expressed antigen (MGEA); meningioma-expressed antigen 11 (MEA11); Menkes Disease (ATP7A) putative Cu++-transporting P-type ATPase; metallothionein 2A (MT2A); metaxin 1 (MTX1); methionine adenosyltransferase II, alpha (MAT2A); methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase (MTHFD2); methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (MTHFD1); methyltransferase, putative; MHC class 1 region; MHC class I antigen (HLA-A2); MHC class I antigen (HLA-A33); MHC class I antigen (HLA-C); MHC class I antigen B*5801 (HLA-B); MHC class I antigen HLA-A (HLA-A); MHC class I antigen HLA-A (HLA-A-2402 allele); MHC class I antigen HLA-A11K; MHC class I antigen HLA-B (B*48 allele); MHC class I antigen HLA-B (HLA-B*1502 allele); MHC class I antigen HLA-B (HLA-B*40MD); MHC class I antigen HLA-B (HLA-B*4103 allele); MHC class I antigen HLA-B gene (HLA-B*4402 variant allele); MHC class I antigen HLA-B GN00110-B*3910; MHC class I antigen HLA-Cw*04011; MHC class I antigen R69772 HLA-A (A*0302); MHC class I antigen SHCHA (HLA-B*4403 variant); MHC class I histocompatibility antigen (HLA-B) (clone C21/14); MHC class I HLA B71; MHC class I HLA-A (Aw33.1); MHC class I HLA-B; MHC class I HLA-B (HLA-B-08NR allele); MHC class I HLA-B*3512; MHC class I HLA-B44.2 chain; MHC class I HLA-B51-cd3.3; MHC class I HLA-C allele; MHC class I HLA-Cw*0803; MHC class I HLA-Cw6; MHC class I lymphocyte antigen A2 (A2.1) variant DK1; MHC class I mic-B antigen; MHC class I polypeptide-related sequence A (MICA); MHC class II DNA Sequence (clone A37G7-1C11); MHC class II DQ-alpha associated with DRw6, DQw1 protein; MHC class II DQ-beta associated with DR2, DQw1 protein; MHC class II HAL-DQ-LTR5 (DQ,w8) DNA fragment, long terminal repeat region; MHC class II HLA-DRB1; MHC class II HLA-DRw11-beta-I chain (DRw11.3); MHC class II lymphocyte antigen (DPw4-beta-1); microsomal stress 70 protein ATPase core (stch); microtubule-associated protein 4 (MAP4); microtubule-associated protein 7 (MAP7); mineralocorticoid receptor (aldosterone receptor) (MLR); minichromosome maintenance deficient (S. cerevisiae) 3 (MCM31); minichromosome maintenance deficient (S. cerevisiae) 3-associated protein (MCM3AP); minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46) (MCM5); mitochondrial 16S rRNA; mitochondrial ATP synthase (F1-ATPase) alpha subunit; mitochondrial ATP synthase c subunit (P1 form); mitochondrial cytochrome b small subunit of complex II; mitochondrial DNA loop attachment sequences (clone LAS34); mitochondrial DNA polymerase accessory subunit precursor (MtPo1B) nuclear gene encoding mitochondrial protein,; mitochondrial DNA, complete genome; mitochondrial inner membrane preprotein translocase Tim17a; mitochondrial loop attachment sequence (clone LAS88); mitochondrial NADH dehydrogenase subunit 2 (ND2); mitochondrial translational initiation factor 2 (MTIF2); mitochondrion cytochrome b; mitogen inducible gene mig-2; mitogen-activated protein kinase-activated protein kinase 3 (MAPKAPK3); MLN51; moesin (MSN); monocytic leukaemia zinc finger protein (MOZ); MOP1 ( ); motor protein (Hs.78504); mouse double minute 2, human homolog of; p53-binding protein (MDM2); M-phase phosphoprotein 6 (MPP-6); M-phase phosphoprotein, mpp11; MPS1; Mr 110,000 antigen; mu-adaptin-related protein-2; mu subunit of AP-4 (MU-ARP2); murine leukemia viral (bmi-1) oncogene homolog (BMI1); mutant (Daudi) beta2- microglobulin; mutated in Alzheimer's diseases (MCC); myeloid cell leukemia sequence 1 (BCL2-related) (MCL1); myeloid cell nuclear differentiation antigeN (MNDA); myeloid differentiation primary response gene (88) (MYD88); myeloid leukemia factor 2 (MLF2); myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 7 (MLLT7); MYH9 (cellular myosin heavy chain); myomesin (M-protein) 2 (165 kD) (MYOM2); myosin IE (MYO1E); myosin light chain kinase (MLCK); myosin phosphatase, target subunit 1 (MYPT1); myosin, heavy polypeptide 9, non-muscle (MYH9); myosin, light polypeptide, regulatory, non-sarcomeric (20 kD) (MLCB); myosin-I beta; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) (MACS); myxovirus (influenza) resistance 1, homolog of murine (interferon-inducible protein p78) (MX1); myxovirus (influenza) resistance 2, homolog of murine (MX2); N-acetylgalactosaminidase, alpha- (NAGA); N-acetylglucosamine receptor 1 (thyroid) (NAGR1); NACP/alpha-synuclein; N-acylaminoacyl-peptide hydrolase (APEH); N-acylsphingosine amidohydrolase (acid ceramidase) (ASAH); NAD+-specific isocitrate dehydrogenase beta subunit precursor (encoding mitochondrial protein); NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13 kD, B13) (NDUFA5); NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 (16 kD, SGDH) (NDUFB5); NADH dehydrogenase (ubiquinone) Fe-S protein 2 (49 kD) (NADH-coenzyme Q eductase) (NDUFS2); NADH dehydrogenase (ubiquinone) flavoprotein 2 (24 kD) (NDUFV2); NADH:ubiquinone dehydrogenase 51 kDa subunit (NDUFV1); Nardilysin (N-arginine dibasic convertase) (NRD1); nascent-polypeptide-associated complex alpha polypeptide (NACA); natural killer cell group 7 sequence (NKG7); natural killer cell transcript 4 (NK4); natural killer-associated transcript 3 (NKAT3); natural killer-associated transcript 5 (NKAT5); natural killer-tumor recognition sequence (NKTR); N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (NDST2); Ndr protein kinase; Nedd-4-like ubiquitin-protein ligase WWP1; nel (chicken)-like 2 (NELL2); N-ethylmaleimide-sensitive factor attachment protein, alpha (NAPA); N-ethylmaleimide-sensitive factor attachment protein, gamma (NAPG); neural precursor cell expressed, developmentally down-regulated 5 (NEDD5); neural precursor cell expressed, developmentally down-regulated 8 (NEDD8); neuregulin 1 (NRG1); neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS); Neurofibromin 2 (bilateral acoustic neuroma) (NF2); neuronal apoptosis inhibitory protein (NAIP); neuronal cell adhesion molecule (NRCAM); neuropathy target esterase (NTE); neurotrophic tyrosine kinase, receptor, type 1 (NTRK1); neutrophil cytosolic factor 4 (40 kD); NG31; nibrin (NBS); NIK; Ninjurin 1; nerve injury-induced protein-1; Nmi; N-myristoyltransferase 1 (NMT1); No arches-like (zebrafish) zinc finger protein (NAR); non-histone chromosome protein 2 (S. cerevisiae)-like 1 (NHP2L1); non-muscle alpha-actinin; non-muscle myosin alkali light chain (Hs.77385); non-neuronal enolase (EC 4.2.1.11); non-receptor tyrosine phosphatase 1; normal keratinocyte substraction library mRNA, clone H22a; notch group protein (N); novel protein; novel T-cell activation protein; N-sulfoglucosamine sulfohydrolase (sulfamidase) (SGSH); nsulin induced gene 1 (INSIG1); ntegrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA14); nterferon, gamma-inducible protein 16 (IFI16); nterleukin 1, beta (IL1RB); nuclear antigen H731-like protein; nuclear antigen Sp100 (SP100); nuclear autoantigenic sperm protein (histone-binding) (NASP); Nuclear domain 10 protein (NDP52); Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2); Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) (NFKB1); nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA); nuclear factor related to kappa B binding protein (NFRKB); nuclear mitotic apparatus protein 1 (NUMA1); nuclear receptor coactivator 2 (GRIP1); nuclear receptor coactivator 3 (AIB3); nuclear receptor coactivator 4 (ELE1); nuclear receptor interacting protein 1 (NRIP1); nuclear respiratory factor 1 (NRF1); nuclear RNA helicase, DECD variant of DEAD box family (DDXL); nuclear transcription factor Y, alpha (NFYA); nuclear transcription factor, X-box binding 1 (NFX1); nuclear transport factor 2 (placental protein 15) (PP15); nucleobindin 1 (NUCB1); nucleolar phosphoprotein p130 (P130); nucleolar protein (KKE/D repeat) (NOP56); nucleolar protein (MSP58); nucleolar protein 1 (120 kD) (NOL1); nucleolar protein p40; nucleolin (NCL); nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1); nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form; nucleoporin 153 kD (NUP153); nucleoporin 98 kD (NUP98); nucleosome assembly protein; nucleosome assembly protein 1-like 1 (NAP1L1); nucleosome assembly protein 1-like 4 (NAP1L4); nucleosome assembly protein, 5′UTR; olfactory receptor (OR7-141); oligodendrocyte myelin glycoprotein (OMG); 0-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (OGT); ORF (Hs.77868); ORF1; MER37; origin recognition complex, subunit 2 (yeast homolog)-like (ORC2L); ornithine aminotransferase (gyrate atrophy) (OAT); ornithine decarboxylase (ODC); ornithine decarboxylase antizyme, ORF 1 and ORF 2; orphan receptor (Hs.100221); OS-9 precurosor; ovel centrosomal protein RanBPM (RANBPM); over-expressed breast tumor protein; oviductal glycoprotein 1, 120 kD (OVGP1); oxidase (cytochrome c) assembly 1-like (OXA1L); oxoglutarate dehydrogenase (lipoamide) (OGDH); oxysterol binding protein (OSBP); OZF; p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) (PAK1); p40; P47 LBC oncogene; p53-induced protein (PIGl1); p62 nucleoporin; p63 mRNA for transmembrane protein; palmitoyl-protein thioesterase (ceroid-lipofuscinosis, neuronal 1, infantile; Haltia-Santavuori disease) (PPT); papillary renal cell carcinoma (translocation-associated) (PRCC); PAR protein; PAX3/forkhead transcription factor gene fusion; paxillin (PXN); PBK1 protein; PDZ domain protein (Drosophila inaD-like) (INALD); peptidase D (PEPD); peptidylprolyl isomerase A (cyclophilin A) (PPIA); peptidylprolyl isomerase D (cyclophilin D) (PPID); peptidylprolyl isomerase E (cyclophilin E) (PPIE); perforin 1 (preforming protein) (PRF1); peroxisomal acyl-CoA thioesterase (PTE1); Peroxisomal acyl-coenzyme A oxidase; peroxisomal farnesylated protein (PXF); phorbol-12-myristate-13-acetate-induced protein (PMAIP1); Phosphate carrier, mitochondrial (PHC); phosphate cytidylyltransferase 1, choline, alpha isoform (PCYT1A); phosphatidylinositol 3-kinase delta catalytic subunit; phosphatidylinositol 4-kinase, catalytic, beta polypeptide (PIK4CB); phosphatidylinositol glycan, class H (PIGH); phosphatidylinositol transfer protein (PI-TPbeta); phosphatidylinositol transfer protein, membrane-associated (PITPNM); phosphatidylinositol-4-phosphate 5-kinase, type II, alpha (PIP5K2A); phosphatidylinositol-4-phosphate 5-kinase, type II, beta (PIP5K2B); phosphodiesterase 7A (PDE7A); phosphodiesterase IB (PDES1B); phosphoglucomutase 1 (PGM1); phosphogluconate dehydrogenase (PGD); phosphoglycerate kinase 1 (PGK1); phosphoglycerate mutase 1 (brain) (PGAM1); phosphoglycerate mutase 2 (muscle) (PGAM2); phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA); phosphoinositide-3-kinase, catalytic, delta polypeptide (PIK3CD); phosphoinositide-3-kinase, catalytic, gamma polypeptide (PIK3CG); phospholipase C; phospholipase C, delta 1 (PLCD1); phospholipase C, gamma 1 (formerly subtype 148) (PLCG1); phospholipid scramblase; phosphoribosyl pyrophosphate synthetase-associated protein 1 (PRPSAP1); phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART); phosphorylase kinase, alpha 2 (liver), glycogen storage disease IX (PHKA2); phosphorylase, glycogen; brain (PYGB); phosphorylase, glycogen; liver (Hers disease, lycogen storage disease type VI) (PYGL); phosphorylation regulatory protein HP-10; phosphotidylinositol transfer protein (PITPN); pigment epithelium-derived factor (PEDF); pim-1 oncogene (PIM1); pinin, desmosome associated protein (PNN); placenta (Diff33); placenta (Diff48); plasminogen activator, urokinase receptor (PLAUR); platelet factor 4 (PF4); platelet/endothelial cell adhesion molecule (CD31 ntigen) (PECAM1); platelet-activating factor acetylhydrolase 2 (40 kD) (PAFAH2); platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45 kD) (PAFAH1B1); platelet-activating factor receptor (PTAFR); pleckstrin (PLEK); pleckstrin homology, Sec7 and coiled/coil domains 1(cytohesin 1) (PSCD1); pleckstrin homology, Sec7 and coiled/coil domains, binding protein (PSCDBP); pM5 protein; PMP69; poly(A) polymerase (PAP); poly(A)-binding protein-like 1 (PABPL1); poly(rC)-binding protein 1 (PCBP1); polyadenylate binding protein; polycystic kidney disease 1 (autosomal dominant) (PKD1); polymerase (DNA directed), beta (POLB); polymerase (DNA directed), gamma (POLG); polymerase (RNA) II (DNA directed) polypeptide A (220 kD) (POLR2A); polymyositis/scleroderma autoantigen 2 (100 kD) (PMSCL2); polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) (PTB); positive regulator of programmed cell death ICH-1L (Ich-1); postmeiotic segregation increased 2-like 12 (PMS2L12); postmeiotic segregation increased 2-like 8 (PMS2L8); potassium inwardly-rectifying channel, subfamily J, member 15 (KCNJ15); potassium voltage-gated channel, KQT-like subfamily, member 1 (KCNQ1); POU domain, class 2, associating factor 1 (POU2AF1); POU domain, class 2, transcription factor 1 (POU2F1); PPAR binding protein (PPARBP); PPAR gamma2; pre-B-cell colony-enhancing factor (PBEF); prefoldin 1 (PFDN1); prefoldin 5 (PRFLD5); pregnancy-associated plasma protein A (PAPPA); pre-mRNA splicing factor SRp20, 5′UTR; preprotein translocase (TIM17); prion protein; prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) (PRNP); procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) (PLOD); procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 1 (P4HA1); procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein P55) (P4HB); profilin 1 (PFN1); progesterone receptor-associated p48 protein (P48); prohibitin (PHB); proliferating cell nuclear antigen (PCNA); proliferation-associated gene A (natural killer-enhancing factor A) (PAGA); proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1); prolyl endopeptidase (PREP); prolylcarboxypeptidase (angiotensinase C) (PRCP); promyelocytic leukemia (PML); properdin P factor, complement (PFC); pro-platelet basic protein (includes platelet basic protein, beta-thromboglobulin, connective tissue-activating peptide III, neutrophil-activating peptide-2) (PPBP); proprotein convertase subtilisin/kexin type 7 (PCSK7); prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) (PSAP); prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (PTGS1); prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2); prostate carcinoma tumor antigen (pcta-1); protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin (PI); protease inhibitor 2 (anti-elastase), proteasome (prosome, macropain) 26S subunit, ATPase, 1 (PSMC1); proteasome (prosome, macropain) 26S subunit, ATPase, 3 (PSMC3); proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4); proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5); proteasome (prosome, macropain) 26S subunit, ATPase, 6 (PMSC6); proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 (PSMD11); proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (PSMD2); proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 (PSMD5); proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) (PMSD7); proteasome (prosome, macropain) 26S subunit, on-ATPase, 12 (PMSD12); proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) (PSME1); proteasome (prosome, macropain) subunit, alpha type, 3 (PSMA3); proteasome (prosome, macropain) subunit, alpha type, 5 (PSMA5); proteasome (prosome, macropain) subunit, alpha type, 7 (PSMA7); proteasome (prosome, macropain) subunit, beta type, 1 (PSMB1); proteasome (prosome, macropain) subunit, beta type, 10 (PSMB10); proteasome (prosome, macropain) subunit, beta type, 6 (PMSB6); proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7) (PSMB8); proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2) (PSMB9); proteasome (prosome, macropain) subunit, beta type, 7 (PSMB7); protective protein for beta-galactosidase (galactosialidosis) (PPGB); protein A alternatively spliced form 2 (A-2); protein activator of the interferon-induced protein kinase (PACT); protein disulfide isomerase-related protein (P5); protein geranylgeranyltransferase type I, beta subunit (PGGT1B); protein homologous to chicken B complex protein, guanine nucleotide binding (H12.3); protein kinase A anchoring protein; protein kinase C substrate 80K-H (PRKCSH); protein kinase C, beta 1 (PRKCB1); protein kinase C, delta (PRKCD); protein kinase C, eta (PRKCH); Protein kinase C-like 1 (PRKCL1); protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1); protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A); protein kinase, DNA-activated, catalytic polypeptide (PRKDC); protein kinase, mitogen-activated 1 (MAP kinase 1; p40, p41) (PRKM1); protein kinase, mitogen-activated 6 (extracellular signal-regulated kinase, p97) (PRKM6); protein kinase, mitogen-activated, kinase 3 (MAP kinase kinase 3) (PRKMK3); protein phosphatase 1, catalytic subunit, alpha isoform (PPP1CA); protein phosphatase 1, regulatory subunit 10 (PPPR10); protein phosphatase 1, regulatory subunit 7 (PPP1R7); protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (PPP2CB); protein phosphatase 2 (formerly 2A), regulatory subunit B′′ (PR 72), alpha isoform and (PR 130), beta isoform (PPP2R3); protein phosphatase 2, regulatory subunit B (B56), alpha isoform (PPP2R5A); protein phosphatase 2, regulatory subunit B (B56), delta isoform (PPP2R5D); protein phosphatase 2, regulatory subunit B (B56), gamma isoform (PPP2R5C); protein phosphatase 2A regulatory subunit alpha-isotype (alpha-PR65); protein phosphatase 4 (formerly X), catalytic subunit (PPP4C); protein tyrosine kinase 2 beta (PTK2B); protein tyrosine phosphatase epsilon; protein tyrosine phosphatase type IVA, member 2 (PTP4A2); protein tyrosine phosphatase, non-receptor type 1 (PTPN1); protein tyrosine phosphatase, non-receptor type 12 (PTPN12); protein tyrosine phosphatase, non-receptor type 2 (PTPN2); protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) (PTPN4); protein tyrosine phosphatase, non-receptor type 6 (PTPN6); protein tyrosine phosphatase, non-receptor type 7 (PTPN7); protein tyrosine phosphatase, receptor type, alpha polypeptide (PTPRA); protein tyrosine phosphatase, receptor type, c polypeptide (PTPRC); protein tyrosine phosphatase, receptor type, M (PTPRM); protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2); protein with polyglutamine repeat (ERPROT213-21); protein-kinase, interferon-inducible double stranded RNA dependent inhibitor (PRKRI); protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1); proteoglycan 1, secretory granule (PRG1); prothymosin, alpha (gene sequence 28) (PTMA); prp28, U5 snRNP 100 kd protein (U5-100K); PRP4/STK/WD splicing factor (HPRP4P); PTK7 protein tyrosine kinase 7 (PTK7); purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4); purinergic receptor P2X, ligand-gated ion channel, 7 (P2RX7); puromycin-sensitive aminopeptidase (PSA); putative ATP(GTP)-binding protein; putative brain nuclearly-targeted protein (KIAA0765); putative chemokine receptor; GTP-binding protein (HM74); putative dienoyl-CoA isomerase (ECH1); putative G-binding protein; Putative human HLA class II associated protein I (PHAP1); Putative L-type neutral amino acid transporter (KIAA0436); putative mitochondrial space protein 32.1; putative nucleic acid binding protein; putative outer mitochondrial membrane 34 kDa translocase Htom34; putative translation initiation factor (SUI1); putative tumor suppressor protein (123F2); pyrroline 5-carboxylate reductase; pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1); pyruvate dehydrogenase (lipoamide) beta (PDHB); Pyruvate dehydrogenase complex, lipoyl-containing component X; E3-binding protein (PDX1); pyruvate kinase, muscle (PKM2); RAB, member of RAS oncogene family-like (RABL); RAB1, member RAS oncogene family (RAB1); RAB11A, member RAS oncogene family (RAB11A); RAB11B, member RAS oncogene family (Rab11B); RAB27A, member RAS oncogene family (RAB27A); RAB5B, member RAS oncogene family (RAB5B); RAB6, member RAS oncogene family (RAB6); RAB7, member RAS oncogene family (RAB7); RAB7, member RAS oncogene family-like 1 (RAB7L1); RAB9, member RAS oncogene family (RAB9); RAD50 (S. cerevisiae) homolog (RAD50); RAD51 (S. cerevisiae) homolog C (RAD51C); Radin blood group (RD); RAE1 (RNA export 1, S.pombe) homolog (RAE1); ralA-binding protein (RLIP76); RAN binding protein 2-like 1 (RANBP2L1); Ran GTPase activating protein 1 (RANGAP1); transforming growth factor, beta receptor II (70-80 kD) (TGFBR2); RAP1A, member of RAS oncogene family (RAP1A); RAR-related orphan receptor C (RORC); RAS guanyl releasing protein 2 (calcium and DAG-regulated); ras homolog gene family, member A (ARHA); ras homolog gene family, member G (rho G) (ARHG); ras homolog gene family, member H (ARHH); ras inhibitor (RIN1); Ras-GTPase activating protein SH3 domain-binding protein 2 (KIAA0660); Ras-GTPase-activating protein SH3-domain-binding protein (G3BP); ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2); RBQ-1; regulator of Fas-induced apoptosis (TOSO); regulator of G protein signalling 6 (RGS6); regulator of G-protein signalling 14 (RGS14); regulator of G-protein signalling 2, 24 kD (RGS2); regulatory factor X, 4 (influences HLA class II expression) (RFX4); regulatory factor X, 5 (influences HLA class II expression (RFX5); replication protein A1 (RPA1); reproduction 8 (D8S2298E); requiem, apoptosis response zinc finger gene (REQ); restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) (RSN); retinoblastoma 1 (including osteosarcoma) (RB1); retinoblastoma binding protein 2 homolog 1 (RBBP2H1); retinoblastoma-binding protein 1 (RBBP1); retinoblastoma-binding protein 2 (RBBP2); retinoblastoma-binding protein 4 (RBBP4); retinoblastoma-binding protein 7 (RBBP7); retinoblastoma-like 2 (p130) (RBL2); retinoic acid receptor responder (tazarotene induced) 3 (RARRES3); retinoic acid receptor, alpha (RARA); retinoic acid responsive (NN8-4AG); retinoid X receptor beta (RXR-beta); REV3 (yeast homolog)-like, catalytic subunit of DNA polymerase zeta (REV3L); Rho GDP dissociation inhibitor (GDI) beta (ARHGDIB); Rho GTPase activating protein 4 (ARHGAP4); Rho-associated, coiled-coil containing protein kinase 2 (ROCK2); ribonuclease 6 precursor (RNASE6PL); ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) (RNASE2); ribonuclease/angiogenin inhibitor (RNH); ribonucleoside diphosphate reductase M1 subunit; ribophorin I (RPN1); ribophorin II (RPN2); ribosomal 18S rRNA; ribosomal 28S RNA; ribosomal protein L10 (RPL10); ribosomal protein L11 (RPL11); ribosomal protein L12 (RPL19); ribosomal protein L14 (RPL14); ribosomal protein L17 (RPL17); ribosomal protein L18 (RPL18); ribosomal protein L18a (RPL18A); ribosomal protein L18a homologue; ribosomal protein L19 (RPL19); ribosomal protein L21 (RPL21); ribosomal protein L22 (RPL22); ribosomal protein L23 (RPL23); ribosomal protein L23a (RPL23A); ribosomal protein L26 (RPL26); ribosomal protein L27 (RPL27); ribosomal protein L27a (RPL27A); ribosomal protein L28 (RPL28); ribosomal protein L29 (RPL29); ribosomal protein L3 (RPL3); ribosomal protein L3 homologue; ribosomal protein L30 (RPL30); ribosomal protein L31 (RPL31); ribosomal protein L32 (RPL32); ribosomal protein L33-like (RPL33L); ribosomal protein L34 (RPL34); ribosomal protein L37 (RPL37); ribosomal protein L37a; ribosomal protein L38 (PRL38); ribosomal protein L4 (RPL4); ribosomal protein L41 (RPL41); ribosomal protein L5 (RPL5); ribosomal protein L6 (RPL6); ribosomal protein L7 (RPL7); ribosomal protein L7a (RPL7A); ribosomal protein L8 (RPL8); ribosomal protein L9 (RPL9); ribosomal protein S10 (RPS10); ribosomal protein S11 (RPS11); ribosomal protein S12 (RPS12); ribosomal protein S13 (RPS13); ribosomal protein S14 (RPS14); ribosomal protein S15 (RPS15); ribosomal protein S16 (RPS16); ribosomal protein S17 (RPS17); ribosomal protein S18; ribosomal protein S19 (RPS19); ribosomal protein S2 (RPS2); ribosomal protein S20 (RPS20); ribosomal protein S21 (RPS21); ribosomal protein S23 (RPS23); ribosomal protein S24 (RPS24); ribosomal protein S25 (RPS25); ribosomal protein S26 (RPS26); ribosomal protein S27 ((metallopanstimulin 1) (RPS27); ribosomal protein S28 (RPS28); ribosomal protein S29 (RPS29); ribosomal protein S3 (RPS3); ribosomal protein S3A (RPS3A); ribosomal protein S4, X-linked (RPS4X); ribosomal protein S4, Y-linked (RPS4Y); ribosomal protein S5 (RPS5); ribosomal protein S6 (RPS6); ribosomal protein S6 kinase, 90 kD, polypeptide 1 (RPS6KA1); ribosomal protein S6 kinase, 90 kD, polypeptide 2 (RPS6KA2); ribosomal protein S7 (RPS7); ribosomal protein S8 (RPS8); ribosomal protein S9 (RPS9); ribosomal protein, large, P0 (RPLP0); ribosomal protein, large, P1 (RPLP1); ribosomal RNA 28S; ribosomal RNA, 16S; ring finger protein 3 (RNF3); ring finger protein 4 (RNF4); ring zinc-finger protein (ZNF127-Xp); RNA (guanine-7-) methyltransferase (RNMT); RNA binding motif protein 5 (RBM5); RNA binding motif, single stranded interacting protein 2 (RBMS2); RNA helicase (putative), (Myc-regulated DEAD box protein) (MRD8); RNA helicase-related protein; RNA pol II largest subunit; RNA polymerase I subunit (RPA40); RTVP-1 protein; S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) (S100A10); S100 calcium-binding protein A11 (calgizzarin) (S100A11); S100calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)(S 100A4); S100 calcium-binding protein A8 (calgranulin A) (S100A8); S100 calcium-binding protein A9 (calgranulin B) (S100A9); S164 gene; S-adenosylmethionine decarboxylase 1 (AMD1); SB class II histocompatibility antigen alpha-chain; SC35-interacting protein 1 (SRRP129); scaffold attachment factor B (SAFB); scRNA molecule, transcribed from Alu repeat; SEC14 (S. cerevisiae)-like (SEC14L); SEC23-like protein B (SEC23B); SEC63 (SEC63); secreted protein, acidic, cysteine-rich (osteonectin) (SPARC); secretory carrier membrane protein 1 (SCAMP1); secretory carrier membrane protein 2 (SCAMP2); secretory carrier membrane protein 3 (SCAMP3); secretory granule proteoglycan core (clones lambda-PG[6,7,8]); selectin L (lymphocyte adhesion molecule 1) (SELL); selectin P ligand (SELPLG); sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (SEMA4D); Ser/Arg-related nuclear matrix protein (plenty of prolines 101-like) (SRM160); serine palmitoyltransferase subunit I (SPTI); serine palmitoyltransferase, subunit II (LCB2); serine protease; serine protease inhibitor, Kunitz type, 2 (SPINT2); serine/threonine kinase 10 (STK10); serine/threonine kinase 19 (STK19); serine/threonine kinase 4 (STK4); serine/threonine protein kinase KKIALRE (KKIALRE); serine/threonine protein-kinase (NIK); serologically defined colon cancer antigen 16 (NY-CO-16); serologically defined colon cancer antigen 33 (SDCCAG33); serum/glucocorticoid regulated kinase (SGK); SET domain, bifurcated 1 (SETDB1); SH2 domain protein 1A, Duncan's disease lymphoproliferative syndrome) (SH2D1A); SH3 binding protein (SAB); SH3 domain protein 1B (SH3D1B); SH3-binding domain glutamic acid-rich protein like (SH3BGRL); SH3-domain GRB2-like 1 (SH3GL1); SHC (Src homology 2 domain-containing) transforming protein 1 (SHC1); siah binding protein 1 (SiahBP1); Sialomucin CD164 (CD164); sialophorin (gpL115, leukosialin, CD43) (SNP); sialyltransferase (STHM); sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) (SIAT1); sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase) (SIAT4A); sialyltransferase 8 (alpha-2, 8-polysialytransferase) D (SIAT8D); signal peptidase 25 kDa subunit; signal recognition particle 14 kD (homologous Alu RNA-binding protein) (SRP14); signal recognition particle 54 kD (SRP54); signal recognition particle 9 kD (SRP9); signal recognition particle receptor (‘docking protein’) SRPR; signal regulatory protein, beta, 1 (SIRP-BETA-1); signal sequence receptor, alpha (translocon-associated protein alpha) (SSR1); signal sequence receptor, beta (translocon-associated protein beta) (SSR2); signal transducer and activator of transcription (STAT5A); signal transducer and activator of transcription 2, 113KD (STAT2); signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3); signal transducer and activator of transcription 5A (STAT5A); signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 (STAM); silencing mediator of retinoid and thyroid hormone action (SMRT); SIT protein; Sjogren syndrome antigen A1 (52 kD, ribonucleoprotein autoantigen SS-A/Ro) (SSA1); SKAP55 homologue (SKAP-HOM); skb1 (S. pombe) homolog (SKB1); skeletal muscle abundant protein; SMA3 (SMA3); small acidic protein; small EDRK-rich factor 2 (SERF2); small inducible cytokine A5 (RANTES) (SCYA5); small inducible cytokine subfamily C, member 2 (SCYC2); small nuclear ribonucleoprotein polypeptide B′′ (SNRPB2); small nuclear ribonucleoprotein polypeptide N (SNRPN); small nuclear ribonucleoprotein polypeptides B and B1 (SNRPB); small nuclear RNA activating complex, polypeptide 5, 19 kD (SNAPC5); smallest subunit of ubiquinol-cytochrome c reductase; SMC (mouse) homolog, X chromosome (SMCX); SMT3B protein (2); SNC19; SNC73 protein (SNC73); solute carrier family 1 (neutral amino acid transporter), member 5 (SLC1A5); Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (SLC11A1); solute carrier family 17 (sodium phosphate), member 3 (SLC17A3); solute carrier family 19 (folate transporter), member 1 (SLC19A1); solute carrier family 2 (facilitated glucose transporter), member 1 (SLC2A1); solute carrier family 23 (nucleobase transporters), member 2 (SLC23A2); solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 (SLC25A11); solute carrier family 31 (copper transporters), member 2 (SLC31A2); solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) (SLC4A2); solute carrier family 4, sodium bicarbonate cotransporter, member 8 (SLC4A8); solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (SLC7A5); solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (SLC7A6); solute carrier family 9 (sodium/hydrogen exchanger), isoform 6 (SLC9A6); somatic cytochrome c (HCS); SON DNA binding protein (SON); son of sevenless (Drosophila) homolog 1 (SOS1); sorcin (SRI); sortilin 1 (SORT1); sortilin-related receptor, L(DLR class) A repeats-containing (SORL1); sorting nexin 1 (SNX1); sorting nexin 2 (SNX2); Sp3 transcription factor (SP3); special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) (SATB1); speckle-type POZ protein (SPOP); spectrin SH3 domain binding protein 1 (SSH3BP1); Spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) (SPTAN1); spermidine/spermine N1-acetyltransferase (SAT); spermine synthase (SMS); SPF31 (SPF31); sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) (SMPD1); spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1) (SCA1); spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2) (SCA2); spinocerebellar ataxia 7 (olivopontocerebellar atrophy with retinal degeneration) (SCA7); spliceosome associated protein (SAP 145); splicing factor (CC1.3) (CC1.3); splicing factor SRp40-1(SRp40); splicing factor, arginine/serine-rich 11 (SFRS11); splicing factor, arginine/serine-rich 7 (35 kD) (SFRS7); Src-like-adapter (SLA); stannin (SNN); STAT induced STAT inhibitor 3 (SSI-3); STE20-like kinase 3 (MST-3); step II splicing factor SLU7 (SLU7); steroid sulfatase; steroid sulfatase (microsomal), arylsulfatase C, isozyme S (STS); sterol carrier protein 2 (SCP2); sterol 0-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 (SOAT1); stimulated trans-acting factor (50 kDa) (STAF50); Stromal antigen 2 (STAG2); stromal interaction molecule 1 (STIM1); structure specific recognition protein 1 (SSRP1); succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA); succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB); succinate dehydrogenase complex, subunit C, integral membrane protein, 15 kD (SDHC); succinate dehydrogenase complex, subunit D, Integral membrane protein (SDHD); succinate-CoA ligase, GDP-forming, beta subunit (SUCLG2); succinyl CoA synthetase; sudD (suppressor of bimD6, Aspergillus nidulans) homolog (SUDD); sulfotransferase family 1A, phenol-preferring, member 1 (SULT1A1); superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1); superoxide dismutase 2, mitochondrial (SOD2); supervillin (SVIL); suppression of tumorigenicity 5 (ST5); suppressor of K+ transport defect 1 (SKD1); suppressor of Ty (S.cerevisiae) 3 homolog (SUPT3H); suppressor of Ty (S.cerevisiae) 4 homolog 1 (SUPT4H1); suppressor of Ty (S.cerevisiae) 5 homolog (SUPT5H); suppressor of Ty (S.cerevisiae) 6 homolog (SUPT6H); suppressor of variegation 3-9 (Drosophila) homolog 1 (SUV39H1); survival of motor neuron 1, telomeric (SMN1); SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2); SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4); SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 (SMARCC2); SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (SMARCE1); synaptobrevin-like 1 (SYBL1); synaptosomal-associated protein, 23 kD (SNAP23); syndecan binding protein (syntenin) (SDCBP); synovial sarcoma, translocated to X chromosome (SSXT); syntaxin 16; syntaxin 3A (STX3A); syntaxin 6 (STX6); SYNTAXIN BINDING PROTEIN 3 (UNC-18 HOMOLOG 3) (UNC-18C); syntaxin-16C; SYT interacting protein (SIP); T cell activation, increased late expression (TACTILE); T cell receptor V alpha gene segment V-alpha-7 (clone IGRa11); T cell receptor V alpha gene segment V-alpha-w27; T3 receptor-associating cofactor-1; tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) (TAZ); tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (TNKS); TAR DNA-binding protein-43; Tat interactive protein (60kD) (TIP60); TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55 kD (TAF2F); TATA box binding protein (TBP)-associated factor, RNA polymerase II, G, 32 kD (TAF2G); TATA box binding protein (TBP)-associated factor, RNA polymerase II, I, 28 kD (TAF2I); Tax1 (human T-cell leukemia virus type I) binding protein 1 (TAX1BP1); TBP-associated factor 172 (TAF-172); T-cell death-associated gene 8 (TDAG8); T-cell leukemia/lymphoma 1A (TCL1A); T-cell receptor (delta D2-J1-region) (clone K3B); T-cell receptor delta gene D2-J1-region, clone K3B; T-cell receptor germline beta chain gene V-region (V) V-beta-MT1-1; T-cell receptor germline beta-chain gene J2.1 exon; T-cell receptor germline delta-chain D-J region; T-cell receptor interacting molecule (TRIM) protein; T-cell receptor rearranged delta-chain, V-region (V-delta 3-J); T-cell receptor, alpha (V,D,J,C) (TCRA); T-cell receptor, beta cluster (TCRB); T-cell receptor, delta (V,D,J,C) (TCRD); T-cell, immune regulator 1 (TCIRG1); TCF-1 mRNA for T cell factor 1; TCR eta =T cell receptor(eta-exon); TCR V Beta 13.2; TERA; testis enhanced gene transcript (TEGT); tetracycline transporter-like protein (TETRAN); tetratricopeptide repeat domain 1 (TTC1); tetratricopeptide repeat domain 2 (TTC2); tetratricopeptide repeat domain 3 (TTC3); TGFB1-induced anti-apoptotic factor 1 (TIAF1); thioredoxin reductase 1 (TXNRD1); threonyl-tRNA synthetase (TARS); thrombin inhibitor; thrombospondin 1 (THBS1); thromboxane A synthase 1 (platelet, cytochrome P450, subfamily V) (TBXAZ1); thymidine kinase 2, mitochondrial (TK2); thymidylate kinase (CDC8); thymine-DNA glycosylase (TDG); Thymosin, beta 10 (TMSB10); thymosin, beta 4, X chromosome (TMSB4X); thyroid autoantigen 70 kD (Ku antigen) (G22P1); thyroid hormone receptor coactivating protein (SMAP); thyroid hormone receptor interactor 7 (TRIP7); thyroid hormone receptor interactor 8r (TRIP8); thyroid hormone receptor-associated protein, 230 kDa subunit (TRAP230); thyroid receptor interacting protein 15 (TRIP15); TI-227H; TIA1 cytotoxic granule-associated RNA-binding protein (TIA1); tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) (TIMP1); tissue inhibitor of metalloproteinase 2 (TIMP2); tissue specific transplantation antigen P35B (TSTA3); titin (TTN); TNF receptor-associated factor 2 (TRAF2); TNF receptor-associated factor 3 (TRAF3); toll-like receptor 1 (TLR1); toll-like receptor 2 (TLR2); toll-like receptor 4 (TLR4); toll-like receptor 5 (TILR5); topoisomerase (DNA) I (TOP1); topoisomerase (DNA) II beta (180 kD) (TOP2B); topoisomerase (DNA) III beta (TOP3B); TR3beta; TRAF family member-associated NF-kB activator (TANK); transaldolase 1 (TALDO1); transaldolase-related protein; transcobalamin II (TCII); transcription elongation factor B (SIII), polypeptide 1-like (TCEB1L); transcription elongation factor B (SIII), polypeptide 3 (110 kD, elongin A) (TCEB3); transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) (TCF12); transcription factor 17 (TCF17); transcription factor 4 (TCR4); transcription factor 6-like 1 (mitochondrial transcription factor 1-like) (TCF6L1); transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2); transcription factor binding to IGHM enhancer 3 (TFE3; transcription factor IL-4 Stat; transcription factor TFIID; transcriptional adaptor 2 (ADA2, yeast, homolog)-like (TADA2L); transducin (beta)-like 1 (TBL1); transducin-like enhancer of split 3, homolog of Drosophila E(sp1) (TLE3); Transformation/transcription domain-associated protein (TRRAP); transformation-sensitive, transforming growth factor beta-stimulated protein TSC-22 (TSC22); transforming growth factor, beta receptor III (betaglycan, 300 kD) (TGFBR3); transforming growth factor, beta-induced, 68 kD (TGFBI); transgelin 2 (TAGLN2); trans-Golgi network protein (46, 48, 51 kD isoforms) (TGN51); transient receptor potential channel 1 (TRPC1); transketolase (Wernicke-Korsakoff syndrome) (TKT); translation factor sui1 homolog (GC20); translin (TSN); translin-associated factor X (TSNAX); transmembrane glycoprotein (A33); transmembrane protein (63 kD), endoplasmic reticulum/Golgi intermediate compartment (P63); transmembrane protein 1 (TMEM2); transmembrane trafficking protein (TMP21); transporter 1, ABC (ATP binding cassette) (TAP1); Treacher Collins-Franceschetti syndrome 1 (TCOF1); triosephosphate isomerase 1 (TPI1); tropomyosin; tropomyosin 4 (TPM4); TRPM-2 protein; tryptophan rich basic protein (WRB); tryptophanyl-tRNA synthetase (WARS); Ts translation elongation factor, mitochondrial (TSFM); ttopoisomerase (DNA) II beta (180 kD); Tu translation elongation factor, mitochondrial (TUFM); tuberous sclerosis 1 (TSC1); tuberous sclerosis 2 (TSC2); tubulin, alpha 1 (testis specific) (TUBA1); tubulin, alpha, ubiquitous (K-ALPHA-1); tubulin-specific chaperone c (TBCC); tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10); tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13); tumor necrosis factor (ligand) superfamily, member 14 (TNFSF14); tumor necrosis factor (ligand) superfamily, member 6 (TNFSF6); tumor necrosis factor (ligand) superfamily, member 8 (TNFSF8); tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains (FIP2); Tumor necrosis factor receptor superfamily member 7 (TNFRSF7); tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B); tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C); tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein) (TNFRSF12); tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14); tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B); tumor necrosis factor receptor superfamily, member 6 (TNFRSF6); tumor necrosis factor receptor superfamily, member 7 (TNFRSF7); tumor necrosis factor, alpha-induced protein 2 (TNFAIP2); tumor necrosis factor, alpha-induced protein 3 (TNFAIP3); tumor protein 53-binding protein, 1 (TP53BP1); tumor protein p53 (Li-Fraumeni syndrome) (TP53); Tumor protein p53-binding protein (TP53BPL); tumor protein, translationally-controlled 1 (TPT1); tumor rejection antigen (gp96) 1 (TRA1); tumorous imaginal discs (Drosophila) homolog (TID1); TXK tyrosine kinase (TXK); type II integral membrane protein (NKG2-E); TYRO protein tyrosine kinase binding protein (TYROBP); tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB); tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ); Tyrosine kinase 2 (TYK2); tyrosyl-tRNA synthetase (YARS); U1 small nuclear RNA; U2(RNU2) small nuclear RNA auxillary factor 1 (non-standard symbol) (U2AF1); U22 snoRNA host gene (UHG); U4/U6-associated RNA splicing factor (HPRP3P); U49 small nuclear RNA; U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p (PRP8); U5 snRNP-specific protein, 116 kD (U5-116KD); U5 snRNP-specific protein, 200 kDa (DEXH RNA helicase family) (U5-200-KD); Uba80 mRNA for ubiquitin; ubiquinol-cytochrome c reductase (6.4 kD) subunit (UQCR); ubiquitin A-52 residue ribosomal protein fusion product 1 (UBA52); ubiquitin activating enzyme El-like protein (GSA7); ubiquitin C (UBC); ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) (UCHL3); ubiquitin fusion degradation 1-like (UFD1L); ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) (UBE3A); ubiquitin specific protease 10 (USP10); ubiquitin specific protease 11 (USP11); ubiquitin specific protease 15 (USP15); ubiquitin specific protease 19 (USP19); ubiquitin specific protease 4 (proto-oncogene) (USP4); ubiquitin specific protease 7 (herpes virus-associated) (USP7); ubiquitin specific protease 8 (USP8); ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) (UBE1); ubiquitin-activating enzyme E1, like (UBE1L); UBIQUITIN-BINDING PROTEIN P62; phosphotyrosine independent ligand for the Lck SH2 domain p62 (P62); ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1); ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2); ubiquitin-conjugating enzyme E2B (RAD6 homolog) (UBE2B); ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7) (UBE2G2); ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8) (UBE2H); ubiquitin-conjugating enzyme E2L 1 (UBE2L1); ubiquitin-conjugating enzyme E2L 3 (UBE2L3); ubiquitin-conjugating enzyme E2L 6 (UBE2L6); ubiquitin-like 1 (sentrin) (UBL1); UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) (GALNT2); unactive progesterone receptor, 23 Kd (P23); unconventional myosin-ID (MYO1F); uncoupling protein homolog (UCPH); uppressor of Ty (S.cerevisiae) 6 homolog; upregulated by 1,25-dihydroxyvitamin D-3 (VDUP1); upstream binding factor (hUBF); UV radiation resistance associated gene (UVRAG); vacuolar proton-ATPase, subunit D; V-ATPase, subunit D (ATP6DV); v-akt murine thymoma viral oncogene homolog 1 (AKT1); Vanin 2 (VNN2); vasodilator-stimulated phosphoprotein (VASP); vav 1 oncogene (VAV1); vav 2 oncogene (VAV2); v-crk avian sarcoma virus CT10 oncogene homolog (CRK); v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (ERBB3); Vesicle-associated membrane protein 1 (synaptobrevin 1) (VAMP1); vesicle-associated membrane protein 3 (cellubrevin) (VAMP3); v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS); villin 2 (ezrin) (VIL2); villin-like protein; vimentin (VIM); vinculin (VCL); vitamin A responsive; cytoskeleton related (JWA); v-jun avian sarcoma virus 17 oncogene homolog (JUN); v-myb avian myeloblastosis viral oncogene homolog (MYB); voltage-dependent anion channel 1 (VDAC1); voltage-dependent anion channel 3 (VDAC3); von Hippel-Lindau syndrome (VHL); v-raf murine sarcoma 3611 viral oncogene homolog 1 (ARAF1); v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1); v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) (RALB); V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)) (RELA); v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (LYN); WD repeat domain 1 (WDR1); WD-repeat protein (HAN11); Williams-Beuren syndrome chromosome region 1 (WBSCR1); Wiskott-Aldrich syndrome protein interacting protein (WASPIP); X (inactive)-specific transcript (XIST); xeroderma pigmentosum, complementation group C (XPC); XIAP associated factor-1; XIB; X-linked anhidroitic ectodermal dysplasia; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80 kD) (XRCC5); XRP2 protein; yeloid differentiation primary response gene (88) (MYD88); zeta-chain (TCR) associated protein kinase (70kD) (ZAP70); zinc finger protein (Hs.47371); zinc finger protein (Hs.78765); zinc finger protein 10 (KOX 1) (ZNF10); zinc finger protein 136 (clone pHZ-20) (ZNF136); zinc finger protein 140 (clone pHZ-39) (ZNF140); zinc finger protein 143 (clone pHZ-1) (ZNF143); zinc finger protein 148 (pHZ-52) (ZNF148); zinc finger protein 173 (ZNF173); zinc finger protein 198 (ZNF198); zinc finger protein 200 (ZNF200); zinc finger protein 207 (ZNF207); zinc finger protein 216 (ZNF216); zinc finger protein 217 (ZNF217); zinc finger protein 230 (ZNF230); Zinc finger protein 239 (ANF239); zinc finger protein 261 (ZNF261); zinc finger protein 262 (ANF262); zinc finger protein 263 (ZNF263); zinc finger protein 264 (ZNF264); zinc finger protein 42 (myeloid-specific retinoic cid-responsive) (ZNF42); zinc finger protein 45 (a Kruppel-associated box (KRAB) domain polypeptide) (ZNF45); zinc finger protein 76 (expressed in testis) (ZNF76); zinc finger protein 84 (HPF2) (ZNF84); zinc finger protein 85 (ZNF85)); zinc finger protein 9 (ZNF9); zinc finger protein C2H2-25 (ZNF25); zinc finger protein clone L3-4; zinc finger protein homologous to Zfp-36 in mouse (ZFP36); zinc finger protein HZF4; zinc finger protein RIZ; zinc finger protein, subfamily 1A, 1 (Ikaros) (LYF1); zinc finger transcriptional regulator (GOS24); zinc-finger helicase (hZFH); Zn-15 related zinc finger protein (rlf); ZNF80-linked ERV9 long terminal repeat; ZW10 (Drosophila) homolog, centromere/kinetochore protein (ZW10); and zyxin (ZYX);
thereby profiling gene expression in a human subject.

2. The method of claim 1, wherein determining the level is performed using at least one oligonucleotide of predetermined sequence.

3. The method of claim 2, wherein the at least one oligonucleotide is specific for RNA encoded only by the gene in blood of human subjects, and/or is specific for cDNA complementary to RNA encoded only by the gene in blood of human subjects.

4. The method of claim 3, wherein determining the level is performed by amplifying of RNA encoded by the gene to form amplified product, using at least one primer, and quantifying the amplified product, wherein the at least one oligonucleotide comprises the at least one primer.

5. The method of claim 3, wherein determining the level is performed by hybridizing cDNA complementary to RNA encoded by the gene with at least one immobilized probe to form hybridization product, and quantifying the hybridization product, wherein the at least one oligonucleotide comprises the at least one probe.

6. The method of claim 1, wherein determining the level is performed by amplifying RNA encoded by the gene.

7. The method of claim 1, wherein determining the level is performed using an immobilized probe.

8. The method of claim 1, wherein determining the level is performed by quantifying cDNA generated from RNA encoded by said gene.

9. The method of claim 1, wherein determining the level is performed by quantifying EST generated from RNA encoded by the gene.

10. The method of claim 1, wherein the level of RNA encoded by the gene is determined relative to a level of RNA encoded by an internal control gene in the blood sample.