UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON , D.C. 20460 

### MAY 25 

## 2011

OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION 

### MEMORANDUM
SUBJECT: BEAD Chemical Profile for Registration Review: Amitrole: PC Code 004401
Kaitlin Rienzo-Stack, Biologist Biological Analysis Branch**J~** Jihad Alsadek, Economist 

# ..J' Science Information and Analysis Branch Andrew 

### Lee, Economist 

# jJ.L.(. Economic Analysis Branch 

# 'f" Biological and Economic Analysis Division (7503P) Amet Jones, Chief 

# /1**k·\rta~,..-** Biological Analysis

## Branch**J/f}** Diann Sims, Chief

# A"""~Qr**I ' 6dl/~;1;~**  Science

## Informatio~~alysi~ranch Timothy Kiely. Chief

# fA_~ Economic Analysis Branch IIV\.. Biological and Economic Analys ivision (7 03 ) 

### FROM:

THRU:

TO: Kaitlin Keller, Chemical Review Manager Risk Management and Implementation, Branch 3 Pesticide Reevaluation Division (7508P)


### Product Review Panel date: April 6, 2011 

### INTRODUCTION The purpose ofthis document is to convey usage information and a broad overview ofthe pest management roles ofpesticides that are beginning to undergo registration review
. The anticipated audience consists ofthe team ofEPA staffcurrently evaluating the registration status ofamitrole, and eventually the general public
. This document builds upon the data already provided in the "Usage and Label Use Data Packages" that are also provided to RegistrationReview teams by BEAD. The document is based on information and data available to BEAD as ofMarch 30,2011. Amitrole is a triazole herbicide. It was previously classified as a restricted use pesticide but that designation was rescinded following mitigation measures and product and use cancellations. While it is used internationally on orchards and other agricultural crops, there are no agricultural use sites for amitrole registered by the US EPA. Weeds resistant to amitrole have been documented in other countries but none are known ofin the United States at this time. 

### USE SITES Agricultural Use Sites There are no registered agricultural use sites for amitrole in the U.S. Non-Agricultural Use Sites • Industrial outdoor construction areas • Outdoor buildings and structures
• Rights-of-way, fencerows, hedgerows
• Uncultivated areas, soils • Paved private roads and sidewalks COMMON FORMULATIONS AND APPLICATION METHODS Amitrole is available as soluble powder, granular and pellet formulations. It is applied as a spray using boom sprayer. USAGE Agricultural There are no registered agricultural crops for amitrole. Non-Agricultural Less than 5 lbs. a.i. ofamitrole are used annually on rights-of-way in California. This is the only usage data currently available to EPA. for amitrole, See section "INFORMATION THAT MAY BE USEFUL FOR BEAD'S FUTURE WORK ON AMITROLE" below for information that could help improve the Agency's understanding ofamitrole usage.
BIOLOGICAL ASPECTS RELEVANT TO AMITROLE Amitrole is a triazole herbicide, classified as a Group F3 chemical by the Herbicide Resistance Action Committee (HRAC 2009). There are 4 weed species with known, documented resistance to Group F3 herbicides (Heap 2011). Ofthose, all 4 have known documented resistance to amitrole specifically (Table 1). The absence ofincidents ofamitrole-resistant weeds in the United States in this table does not necessarily mean there are not any but rather that none are known and/or documented at this time.Table 1: Known, documented incidents ofweed resistance to amitrole Common Resistant Weed Name Incidents Years Locations Crop Poaannua Putnualbluegrass 

### 1 1983 Belgium orchards Polygonum Prostrate aviculare knotweed 

### 1 1984 Belgium apple Agrostis Creeping stolonifera bentgrass I 

### 1986 Belgium pears 

### 1988, railways, roadsides, Lolium rigidum Rigid ryegrass 

### 1 2008 Australia vineyards Source: Heap 2011
mSTORY OF BEAD ASSESSMENTS FOR AMITROLE There are no BEAD assessments for amitrole, INFORMATION THAT MAY BE USEFUL FOR BEAD'S FUTURE WORK ON
" AMITROLE Obtaining additional information on the following items would improve future BEAD assessments ofamitrole and may be required as part ofthe registration review ofthis pesticide. Usage data are needed on the following non-agricultural sites:

• Industrial/ConstructionAreas (Outdoor)

• Non-agricultural OutdoorBuildings/Structures

• Non-agricultural Right-of- Way/Fencerows/Hedgerows

• Non-agricultural UncultivatedAreas/Soils

• PavedAreas (Private Roads/Sidewalks)
REFERENCES Heap, I. 2011. The International Survey ofHerbicide Resistant Weeds. Accessed February, 2011. Available online at www.weedscience.com Herbicide Resistance Action Committee. 2009. Classification ofHerbicides According to Site of Action. Last updated 2009. Accessed February, 2011. Available online at; http://www.hracglobal.com/Publications/ClassificationofHerbicideSiteofAction/tabid/222 lDefault.aspx http://www.cdpr.ca.gov/docs/pur/purmain.htm. 2007-2009