----

----

|   |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         |
|--------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 1.     | SERVICES: INC Research will render such services (hereinafter “Services”) as may be necessary to complete in a professional manner the project described below:                                                                                                                                                                                                                                                                                                                                                                  |
|   |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         |
|   | Protocol # PBT2-203: A randomized, double-blind, placebo controlled study to assess the safety and tolerability and efficacy of PBT2 in patients with early to mid-stage Huntington disease.                                                                                                                                                                                                                                                                                                                                                 |
|   |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         |
|   | INC Research will perform the Services as specified in Attachment A to this Work Order.                                                                                                                                                                                                                                                                                                                                                                                                                                                      |
|   |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         |
| 2.     | PROJECT SCHEDULE: The major project milestones and target dates are described in Attachment B to this Work Order. Both parties agree that the Project Schedule is a reasonable schedule for the Services to be performed and will put forth all reasonable efforts to comply with these dates.                                                                                                                                                                                                                                               |
|   |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         |
| 3.     | COMPENSATION AND EXPENSES: Sponsor shall pay the fees for INC Research’s Services in accordance with the Project Budget and Payment Schedule provided in Attachment C of this Work Order. INC Research shall invoice Sponsor for taxes or duties actually incurred by INC Research which are imposed upon INC Research by any governmental agency, including, but not limited to Value Added Tax, Stamp Tax, and/or General Sales Tax, as a result of this Agreement with the exception of taxes based on INC Research’s income. |

| INCResearch Australia Pty Limited - 1002213                          |   |
|----------------------------------------------------------------------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |

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| 4. | NOTICES AND PAYMENTS: All communications, notices and payments required under this Work Order shall be mailed by first class mail, postage prepaid, or by overnight carriers, to the respective parties at the addresses set forth below, or to such other addresses as the parties may from time to time specify in writing. |
|----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   |                |                         |
|--------|---------------------|------------------------------|
|   | If to Sponsor:      |                         |
|   |                | Carolyn Stone                |
|   |                | Clinical Program Manager     |
|   |                | Prana Biotechnology Limited  |
|   |                | Level 2                      |
|   |                | 369 Royal Parade             |
|   |                | Parkville VIC 3052 Australia |
|   |                | cstone@pranabio.com          |
|   |                |                         |
|   |                | Cc: Caroline Herd            |
|   |                | cherd@pranabio.com           |
|   |                |                         |
|   | If to INC Research: |                         |

|   | For Communications:       | Contracts Management              |
|--------|---------------------------|-----------------------------------|
|   |                      | INCResearch Australia Pty Limited |
|   |                      | 124 Lipson Street                 |
|   |                      | Port Adelaide SA 5015 Australia   |
|   |                      | Phone: +61 (0) 8 7202 1500        |
|   |                      | Facsimile: +61 (0) 8 7202 1599    |
|   |                      |                              |
|   | For Payments (Via Wire):  |                              |
|   |                      |                              |
|   | Beneficiary Bank:         | HSBC Bank Australia Ltd           |
|   | Beneficiary Bank Address: | Ground Floor, 55 Grenfell Street  |
|   |                      | Adelaide SA 5000, Australia       |
|   | Account Name:             | INCResearch Australia Pty Limited |
|   | BSB (Routing Number):     |                              |
|   | Account Number:           |                              |
|   | Swift:                    |                              |

| 5. | TRANSFER OF OBLIGATIONS: Sponsor assigns the responsibilities pertaining to the Study to INC Research as indicated in Attachment A, Services, |
|----|-----------------------------------------------------------------------------------------------------------------------------------------------|

| INCResearch Australia Pty Limited - 1002213                          |   |
|----------------------------------------------------------------------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |

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|              |         |   |
|-------------------|--------------|--------|
| By:               |              |   |
| Name:   | Dianne Angus |   |
| Title:            | C.O.O.       |   |
| Date:             | 27-3-2013    |   |

| By:               |                                                         |   |
|-------------------|---------------------------------------------------------|--------|
| Name:   | Garth Tierney                                           |   |
| Title:            | Regional General Manager, Australia and South East Asia |   |
| Date              | 28/3/2013                                               |   |

| INCResearch Australia Pty Limited - 1002213                          |   |
|----------------------------------------------------------------------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |

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|              |         |   |
|-------------------|--------------|--------|
| By:               |              |   |
| Name:   | Dianne Angus |   |
| Title:            | C.O.O.       |   |
| Date:             | 27-3-2013    |   |

| By:               |                                                    |   |
|-------------------|---------------------------------------------------------|--------|
| Name:   | Garth Tierney                                           |   |
| Title:            | Regional General Manager, Australia and South East Asia |   |
| Date:             |                                                    |   |

| INCResearch Australia Pty Limited - 1002213                          |   |
|----------------------------------------------------------------------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |

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|                                                      |                                                                                                          |
|-----------------------------------------------------------|---------------------------------------------------------------------------------------------------------------|
| Project Specifications                                    |
| GENERAL                                                   |                                                                                                          |
| Drug Name                                                 | PBT2                                                                                                          |
| Indication                                                | Huntington Disease                                                                                            |
| Phase                                                     | II                                                                                                            |
| PROJECT MANAGEMENT                                        |
| Number of SponsorTeleconferences                          | 12 x 1 hour Teleconference monthlyUp to 4 Face to Face meetings if needed                                     |
| STATISTICAL ANALYSIS/MEDICAL WRITING                      |
| Number of Statistical Analyses                            | 19                                                                                                            |
| Number of UniqueTables/Listings/Figures for FinalAnalysis | 14 Unique Tables / 38 Listings / 36 Figures                                                                   |
| Number Replicate Tables forFinal Analysis                 | 20 Replicate Tables                                                                                           |
| Import of Biomarker, PK, ECGand Imaging data              | 2 transfers for each data type                                                                                |
| Final Deliverable                                         | Final Analysis Sets and Clinical Study Report                                                                 |
|                                                      |                                                                                                          |
| AUDIT SERVICES                                            |
| Number of Countries                                       | 2 (USA & Australia)                                                                                       |
| Number of Audits                                          | 2 X GCP Audit & 1 X Vendor Audit                                                                          |
| Travel Expense                                            | The travel cost and travel time will depend upon thelocation of sites and external service provider selected. |

| INCResearch Australia Pty Limited - 1002213                          |   |
|----------------------------------------------------------------------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |

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| ACTIVITY | Prana                                                                             | INCResearch |
|----------|-----------------------------------------------------------------------------------|-------------|
| 1.       | Pre-Trial Regulatory Filing/Country Level                                         |        |   |
| 1.1      | Compile relevant regulatory documents                                             | X           |   |
| 1.2      | Obtain regulatory approval                                                        | X           |   |
| 1.3      | Answer regulatory queries                                                         | X           |   |
| 1.4      | Manage interactions with regulatory authorities                                   | X           |   |
| 2.       | Study Documents Preparation/Study Docs                                            |        |   |
| 2.1      | Design Study                                                                      | X           |   |
| 3.       | Protocol Versions                                                                 |        |   |
| 3.1      | Write protocol                                                                    | X           |   |
| 3.2      | QC approved protocol                                                              | X           |   |
| 3.3      | Print final protocol copies in English                                            | X           |   |
| 3.4      | Final protocol translations and certification                                     | X           |   |
| 3.5      | Printing of translation of protocol                                               | X           |   |
| 4.       | Study Guide Versions                                                              |        |   |
| 4.1      | Prepare study procedures manual                                                   | X           |   |
| 4.2      | Print study procedures manual                                                     | X           |   |
| 5.       | Investigator Brochure & Study Aids                                            |        |   |
| 5.1      | Prepare Clinical Investigator Brochure                                            | X           |   |
| 5.2      | Print Clinical Investigator Brochure                                              | X           |   |
| 5.3      | Prepare study aids                                                                | X           |   |
| 5.4      | Print study aids                                                                  | X           |   |
| 6.       | Informed Consent Form                                                             |        |   |
| 6.1      | Write template Participant Information Sheet (PIS) and Informed Consent Form (CF) | X           |   |
| 6.2      | Review site specific PIS and ICF                                                  | X           |   |
| 6.3      | Translations of PIS and ICF                                                       | X           |   |
| 7.       | Participant DiariesPre-Study Preparation and Recruitment/Study                    |        |   |
| 7.1      | Design and finalise diary cards or equivalent                                     | X           |   |

| INCReseareh Australia Pty Limited - 1002213                          |   |
|----------------------------------------------------------------------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |

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| 7.2  | Translate diary cards                                                       | X      |   |
|------|-----------------------------------------------------------------------------|--------|--------|
| 7.3  | Print diary cards                                                           | X      |   |
| 7.4  | Site/Sponsor Trial Master File organisation                                 | X      |   |
| 7.5  | Prepare study site files                                                    | X      |   |
| 7.6  | Print study site files                                                      | X      |   |
| 8.   | Evaluation Visits                                                           |   |   |
| 8.1  | Identify trial sites                                                        | X      |   |
| 8.2  | Select Site investigators                                                   | X      |   |
| 8.3  | Evaluate trial site                                                         | X      |   |
| 8.4  | Prepare and finalise confidentiality agreement for investigators            | X      |   |
| 8.5  | Pre-study visits                                                            | X      |   |
| 9.   | Negotiation Visits                                                          |   |   |
| 9.1  | Prepare, negotiate and execute site contractual agreement and budget.       | X      |   |
| 10.  | Ethics                                                                      |   |   |
| 10.1 | Preparation/Co-ordination of IEC/IRB submission                             | X      |   |
| 10.2 | Investigator/Patient indemnity agreement                                    | X      |   |
| 10.3 | Obtain Local IEC/IRB approval                                               | X      |   |
| 10.4 | Pay Ethics Committee                                                        | X      |   |
| 11.  | Investigator Meetings                                                       |   |   |
| 11.1 | Planning/ Administration of Investigator Meetings                           | X      |   |
| 11.2 | Prepare Investigator Meetings Binders/ materials                            | X      |   |
| 11.3 | Attendance/Input at Investigator Meetings                                   | X      |   |
| 11.4 | Train Investigator and Site Personnel                                       | X      |   |
| 12.  | CRO Training/Trainings                                                      |   |   |
| 12.1 | Administration and responsibility for monitor training (SOP, protocol, IMP) | X      |   |
| 12.2 | Attendance/input for monitor training                                       | X      |   |
| 13.  | Project Management                                                          |   |   |
| 13.1 | Administer and track site payments                                          | X      |   |
| 13.2 | Collect pre-study documents e.g. 1572s, CVs, IEC/IRB approvals              | X      |   |
| 13.3 | Development & maintenance of project databases                          | X      |   |

| INCResearch Australia Pty Limited - 1002213                          |   |
|----------------------------------------------------------------------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |

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| 13.4 | Preparation of status reports                                                | X      |   |
|------|------------------------------------------------------------------------------|--------|--------|
| 13.5 | PM Meetings & telephone contacts with Prana                              |   | X      |
| 13.6 | Establishment & maintenance of project files -statistical & CSR only |   | X      |
| 13.7 | Periodic budget & contract review                                        | X      | X      |
| 14.  | Safety/ Pharmacovigilance                                                    |   |   |
| 14.1 | 24/7 Medical Monitor Hotline                                                 | X      |   |
| 14.2 | Generate data for Annual Safety Report (if applicable)                       | X      |   |
| 15.  | Central Laboratory                                                           |   |   |
| 15.1 | Identification of Central Laboratories                                       | X      |   |
| 15.2 | Pre-Qualification Audit of Central Laboratories                              | X      |   |
| 15.3 | Selection of Central Laboratories                                            | X      |   |
| 15.4 | Payment of Central Laboratories                                              | X      |   |
| 15.5 | Management of Central Laboratories                                           | X      |   |
| 15.6 | Organise Project Teleconferences                                             | X      |   |
| 15.7 | Provide status reports                                                       | X      |   |
| 15.8 | Review of clinical laboratory data                                           | X      |   |
| 15.9 | Lab Data transfer to study database                                          | X      |   |
| 16.  | Audits                                                                       |   |   |
| 16.1 | Conduct of GCP audit                                                         |   | X      |
| 16.2 | QA site audits (as per audit plan)                                           |   | X      |
| 16.3 | Final QA audit of report, database, sites (if required) and systems          |   | X      |
| 17.  | Site Initiation Visits/Initiation Days                                       |   |   |
| 17.1 | Conduct site initiation visits & provide written reports                 | X      |   |
| 18.  | Site Monitoring/Monitor Days                                                 |   |   |
| 18.1 | Monitor sites regularly (per GCP)                                            | X      |   |
| 18.2 | Source data verification (SDV) of CRFs                                       | X      |   |
| 18.3 | Provide written monitoring reports                                           | X      |   |
| 18.4 | Review Monitoring Visit Reports                                              | X      |   |
| 18.5 | Perform Drug/Accountability at Site                                          | X      |   |
| 19.  | Site Close-Out                                                               |   |   |
| 19.1 | Perform final drug accountability                                            | X      |   |
| 19.2 | Disposal of unused supplies                                                  | X      |   |

| INCResearch Australia Pty Limited - 1002213                          |   |
|----------------------------------------------------------------------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |

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| 19.3 | Conduct site close-out visit & provide written reports                 | X      |   |
|------|----------------------------------------------------------------------------|--------|--------|
| 20.  | Site management/Site Months                                                |   |   |
| 20.1 | Telephone sites as required                                                | X      |   |
| 20.2 | Shipment and tracking of completed CRFs to Data Management (if applicable) | X      |   |
| 20.3 | Provide status reports                                                     | X      |   |
| 21.  | IMP Packaging and Distribution/Completed Pts                               |   |   |
| 21.1 | Supply IMP to Clinical Trial Supply ESP                                    | X      |   |
| 21.2 | Source and supply of ancillary clinical trial supplies                     | X      |   |
| 21.3 | Shipment and co-ordination of IMP to sites                                 | X      |   |
| 21.4 | Drug tracking: Sponsor → Sites → Destruction         | X      |   |
| 22.  | Case Report Form                                                           |   |   |
| 22.1 | Select EDC Vendor                                                          | X      |   |
| 22.2 | Design of eCRF                                                             | X      |   |
| 22.3 | QC approval of eCRF                                                        | X      |   |
| 22.4 | QA approved eCRF                                                           | X      |   |
| 22.5 | Print eCRFs in English (If applicable)                                     | X      |   |
| 22.6 | Translation of eCRFs                                                       | X      |   |
| 22.7 | Prepare eCRF Instruction Manual                                            | X      |   |
| 23.  | Date Clean-Up/eCRF Pages                                                   |   |   |
| 23.1 | Issue CRF Queries                                                          | X      |   |
| 25.  | Data Management                                                            |   |   |
| 25.1 | Data entry                                                                 | X      |   |
| 25.2 | Medical coding (MedDRA & WHO)                                          | X      |   |
| 25.3 | Data Validation: CRF pre-entry review                                      | X      |   |
| 25.4 | Data Validation: Running validation programs                               | X      |   |
| 25.5 | Data Validation: Query resolution, handling, editing                       | X      |   |
| 25.6 | Data QC/Report                                                             | X      |   |
| 25.7 | Reconciliation of SAEs                                                     | X      |   |
| 25.8 | Transfer Laboratory Data                                                   | X      | X      |
| 25.9 | Database lock                                                              | X      |   |
| 26.  | Statistics                                                                 |   |   |

| INCResearch Australia Pty Limited - 1002213                          |   |
|----------------------------------------------------------------------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |

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| 26.1 | Statistical input into study design                                                               | X      |   |
|------|---------------------------------------------------------------------------------------------------|--------|--------|
| 26.2 | Prepare and finalise Statistical Analysis Plan                                                    |   | X      |
| 26.3 | Perform statistical analysis                                                                      |   | X      |
| 26.4 | Prepare statistical text for inclusion in the Clinical study report                               |   | X      |
| 26.5 | QA checks of statistical text                                                                     |   | X      |
| 27.  | Clinical Study Report                                                                             |   |   |
| 27.1 | Approval of Style Manual for Clinical Study Report                                                | X      |   |
| 27.2 | Prepare ICH format Clinical Study Report                                                          |   | X      |
| 27.4 | Validation of any data conversion                                                                 |   | X      |
| 27.5 | Validation of data transfer                                                                       |   | X      |
| 27.6 | Review of CSR drafts (x2)                                                                         | X      | X      |
| 27.7 | Provide final copy of ICH format Clinical Study Report (Word & PDF), including all appendices |   | X      |
| 27.8 | QC of Clinical Study report                                                                       |   | X      |
| 28.  | Archiving                                                                                         |   |   |
| 28.1 | Assistance with archiving of Investigator Study file if required.                                 |   | X      |
| 28.2 | Database – final archiving                                                             | X      |   |

| INCResearch Australia Pty Limited - 1002213                          |   |   |
|----------------------------------------------------------------------|--------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |   |

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| Timelines         |
|-------------------|
| Start Date        | End Date |
| 1st January 2013  | 1st January 2014 |
| Total - 12 Months |

| INCResearch Australia Pty Limited - 1002213                          |   |   |
|----------------------------------------------------------------------|--------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |   |

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| Total Cost Summary (AUD) |
|--------------------------|
| Direct Costs             | $173,754.00 |
| Pass-Through Costs       | $ 2,310.00 |
| TOTAL PROJECT COST       | $176,064.00 |

|                                                                 |   |   |
|----------------------------------------------------------------------|--------|--------|
| INCResearch Australia Ply Limited - 1002213                          |   |   |
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |   |

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|                                                                 |   |   |
|----------------------------------------------------------------------|--------|--------|
| INCResearch Australia Pty Limited - 1002213                          |   |   |
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |   |

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| Service/Item                                                 |   | Comments                                                                                                                                        |   | Responsibility      |   | Unit             |   | Unit Cost (AUD) |   | Number of Units |   | ItemCost |   | ALD$   |
|--------------------------------------------------------------|--------|-------------------------------------------------------------------------------------------------------------------------------------------------|--------|---------------------|--------|------------------|--------|-----------------|--------|-----------------|--------|----------|--------|--------|
| Data Management & Statistics                             |   |                                                                                                                                            |   |                |   |             |   |            |   |            |   |     |   |   |
| Project familiarization                                      |   | Arrange test data extract from database, assess data structure and data quality. Receive final transfer from HSG                                |   | Clinical Programmer |   | 1hr              |   | 108             |   | 16.00           |   | 1,728    |   |   |
| HSG Meeting (USA)                                            |   | Three days of meetings plus travel time. (Jan Steyn or Melanie Bailey Tippetts and Peter Fursdon). Travel & accommodation arranged by Prana |   |                |   | 40hrs per person |   | 8000            |   | 2.00            |   | 16,000   |   |   |
| Database design                                              |   | Review annotated CRF and database specification documentations                                                                                  |   | Clinical Programmer |   | 0.5hr/dataset    |   | 30              |   | 25.00           |   | 750      |   |   |
| Data Validation Manual                                       |   | Review DVM text/data management plan specifying edit checks                                                                                     |   | CDA                 |   | 40hrs            |   | 104             |   | 16.00           |   | 1,664    |   |   |
| Import BM, PK, ECG and immunology data                       |   | Electronic transfers of Biomarker, PK, ECG and MRI data (Data transfer plans, test transfers & final transfers)                             |   | DBA                 |   | 1 lab source     |   | 1122            |   | 4.00            |   | 4,488    |   |   |
| Statistical Analysis Plan (SAP)                              |   | Includes text and table and listing shells                                                                                                      |   | Statistician        |   | 1 SAP            |   | 9426            |   | 1.00            |   | 9,426    |   |   |
| Identify Protocol Deviations and define Analysis populations |   | Unblinding, Protocol deviations and Definition of populations                                                                                   |   | Statistician        |   | I study          |   | 1600            |   | 1.00            |   | 1,600    |   |   |
| Analysis Datasets                                            |   | Specification, Programming & QC                                                                                                             |   | SAS Programmer      |   | 1 study          |   | 21294           |   | 1.00            |   | 21,294   |   |   |

| INCResearch Australia Pty Limited - 1002213                          |   |   |
|----------------------------------------------------------------------|--------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |   |

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| Service/Item                        |   | Comments                                                                                                                                      |   | Responsibility      |   | Unit                |   | Unit Cost (AUD) |   | Number of Units |   | ItemCost |   | AUD$     |
|-------------------------------------|--------|-----------------------------------------------------------------------------------------------------------------------------------------------|--------|---------------------|--------|---------------------|--------|-----------------|--------|-----------------|--------|----------|--------|----------|
| Production of Tables & Listings |   | 14 Unique tables. Cost per extra $1014 20 Repeat tables. Cost per extra $338 36 Figures, Cost per extra $592 38 Listings. Cost per extra $422 |   | SAS Programmer      |   | 1 study             |   | 52221           |   | 1.00            |   | 52,221   |   |     |
| Statistical Analysis                |   | 19 analysis endpoints. Cost per extra $424                                                                                                    |   | Statistician        |   | 1 analysis endpoint |   | 424             |   | 19.00           |   | 8,056    |   |     |
| Input to Final report               |   | Text for inclusion in study report                                                                                                            |   | Statistician        |   | 1 Study             |   | 5088            |   | 1.00            |   | 5,088    |   |     |
| Unit based Data Management Costs    |   | Program consistency check                                                                                                                     |   | Clinical Programmer |   | 1 check             |   | 60              |   | 1.00            |   | 60       |   |     |
| Unit based Data Management Costs    |   | Raise manual data query                                                                                                                       |   | CDA                 |   | 1 query             |   | 52              |   | 1.00            |   | 52       |   |     |
|                                |   |                                                                                                                                          |   |                |   |                |   |            |   |            |   | Subtotal |   | $122,427 |
| Medical Writing                     |   |                                                                                                                                          |   |                |   |                |   |            |   |            |   |     |   |     |
| Clinical Study Report (CSR)         |   |                                                                                                                                          |   | Medical Writer      |   | per CSR             |   | 25418           |   | 1.00            |   | 25,418   |   |     |
|                                |   |                                                                                                                                          |   |                |   |                |   |            |   |            |   | Subtotal |   | $25,418  |
| Quality Assurance -Site Audits      |   |                                                                                                                                          |   |                |   |                |   |            |   |            |   |     |   |     |
| Quality Assurance Site Audits       |   | GCP Audits preparation time                                                                                                                   |   | QAA                 |   | Site Audit          |   | 1314            |   | 2.00            |   | 2,628    |   |     |
|                                |   | GCP Audits on-site                                                                                                                            |   | QAA                 |   | Site Audit          |   | 2628            |   | 2.00            |   | 5,255    |   |     |
|                                |   | GCP Audits report preparation                                                                                                                 |   | QAA                 |   | Site Audit          |   | 1971            |   | 2.00            |   | 3,941    |   |     |
|                                |   | GCP Audits travel time                                                                                                                        |   | QAA                 |   | Site Audit          |   | 1570            |   | 2.00            |   | 3,140    |   |     |
|                                |   | Review of Audit reports                                                                                                                       |   | QAA                 |   | Site Audit          |   | 443             |   | 2.00            |   | 886      |   |     |
| QA Audit of Vendor(s)               |   |                                                                                                                                          |   | QAA                 |   | Audit               |   | 10059           |   | 1.00            |   | 10,059   |   |     |
|                                |   |                                                                                                                                          |   |                |   |                |   |            |   |            |   | Subtotal |   | $25,909  |
|                                |   |                                                                                                                                          |   |                |   |                |   |            |   |            |   |     |   |     |
|                                |   |                                                                                                                                          |   |                |   |                |   |            |   |            |   | TOTAL    |   | $173,754 |

| INCResearch Australia Pty Limited - 1002213                          |   |   |
|----------------------------------------------------------------------|--------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |   |

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| Expense/Item                               |   | Comments |   | Unit Cost (AUD) |   | Number of Units |   | Item Cost AUD$ |   | AUD$   |
|--------------------------------------------|--------|----------|--------|-----------------|--------|-----------------|--------|----------------|--------|--------|
| Site Visits                                |   |     |   |            |   |            |   |           |   |   |
| Travel Costs (flights/accommodation/taxis) |   |     |   | $l,155/visit    |   | 2               |   | 2,310          |   |   |
|                                       |   |     |   |            |   |            |   | Subtotal       |   | $2,310 |
|                                       |   |     |   |            |   |            |   |           |   |   |
|                                       |   |     |   |            |   |            |   | TOTAL          |   | $2,310 |

| INCResearch Australia Pty Limited - 1002213                          |   |   |
|----------------------------------------------------------------------|--------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |   |

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| INCResearch Australia Pty Limited - 1002213                          |   |   |
|----------------------------------------------------------------------|--------|--------|
| Prana Biotechnology Limited Work Order, Version 3, 30th January 2013 |   |   |

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