Exhibit 10.30

DATED 27th July, 2001

THE MASTER FELLOWS AND  SCHOLARS OF TRINITY COLLEGE  CAMBRIDGE(1)

ACCELRYS LIMITED(2)

ACCELRYS INC(3)

TRINITY COLLEGE (CSP) LIMITED(4)

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AGREEMENT

relating to the grant of a lease of Unit  334 Cambridge Science Park Milton  Road Cambridge

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THIS AGREEMENTis made on 29th July, 2001BETWEEN:

Whereas
the Premises are held by the Landlord which is an exempt charity

NOW IT IS HEREBY AGREEDas follows:

1 Interpretation

2

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3

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2 Landlord's Works

4

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3 Programme

4 Landlord's Variations

5 Site Visits By and Supply of Information to the Tenant

5

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6 Issue of Certificate of Practical Completion

7 Post Completion Works

6

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8 Defects

7

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9 General Conditions

10 Grant of Lease

8

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11 Determination

9

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12 No Demise/Early Access

13 Alienation

14 Declaration of Non-Merger

15 Resolution of Disputes

16 Notices

17 Value Added Tax

10

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18 Statutory Compliance

19 Legal Costs

20 Late Payment

21 No Representations

22 Insurance

23 Guarantee

11

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24 Proper Law

25 Charity

26 Contracts (Rights of Third Parties) Act 1999

27 The Company

This
instrument:

12

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APPENDIX 1

Design packages

1  Structural
Steel Work Connections

2  Curtain
Walling Windows and Wall Cladding

3  Lift

4  Staircase
and Balastrades

5  Atrium
Roofing System

6  Window
Sunshades

7  Revolving
Door

8  Upper
Floor Construction

|The common seal of THE MASTER |  | )
|----------------------------- |  | -
|FELLOWS AND SCHOLARS OF       |  | )
|TRINITY COLLEGE CAMBRIDGE was |  | )
|affixed in the presence of:   |  | )
|                              |  |  
|                              |  |  
|/s/ Jeremy Fairbrother        |  |  
|Senior Bursar                 |  |  
|                              |  |  
|                              |  |  
|/s/ Alexander Simm            |  |  
|Junior Bursar                 |  |  

13

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|Signed as a deed by TRINITY COLLEGE       |  | )
|----------------------------------------- |  | -
|(CSP) LIMITED acting either by a director |  | )
|and its secretary or by two directors     |  | )
|                                          |  |  
|                                          |  |  
|/s/ Jeremy Fairbrother                    |  |  
|Director                                  |  |  
|                                          |  |  
|                                          |  |  
|/s/ Alexander Simm                        |  |  
|Director/Secretary                        |  |  

|The common seal of ACCELRYS LIMITED |  | )
|----------------------------------- |  | -
|was affixed in the presence of:     |  | )
|                                    |  |  
|                                    |  |  
|/s/ Joseph A. Mollica               |  |  
|Director                            |  |  
|                                    |  |  
|                                    |  |  
|/s/ Bruce C. Myers                  |  |  
|Secretary                           |  |  

|Signed as a deed by ACCELRYS INC          |  | )
|----------------------------------------- |  | -
|acting by its duly authorised signatories |  | )
|                                          |  |  
|                                          |  |  
|/s/ Joseph A. Mollica                     |  |  
|Duly authorised signatory                 |  |  
|                                          |  |  
|                                          |  |  
|/s/ Bruce C. Myers                        |  |  
|Duly authorised signatory                 |  |  

14

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Exhibit 10.30

DATED                        2001

THE MASTER FELLOWS AND  SCHOLARS OF TRINITY COLLEGE  CAMBRIDGE(1)

ACCELRYS LIMITED(2)

ACCELRYS INC(3)

TRINITY COLLEGE (CSP) LIMITED(4)

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LEASE

of Unit 334 Phase VI  Cambridge Science Park

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|Term:              |  | 20 years (plus broken quarter if any)                                                                                                                                                                           |  |  |  | 
|------------------ |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  |  |  | 
|Initial Rent:      |  | £900,000 per annum                                                                                                                                                                                              |  |  |  | 
|Rent Review Dates: |  | [Insert 5th, 10th and 15th anniversary of Practical Completion or (if Practical Completion not a quarter day) the quarter day succeeding Practical Completion]                                                  |  |  |  | 
|Expiry Date:       |  | [Insert day preceding [    ] anniversary of Practical Completion or (if Practical Completion is not a quarter day) the day preceding the [    ] anniversary of the quarter day
succeeding practical completion] |  |  |  | 

Mills & Reeve
Cambridge

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Contents

|1          |  | Definitions and Interpretation                        |  | 1                                                                  
|---------- |  | ----------------------------------------------------- |  | -------------------------------------------------------------------
|2          |  | The demise habendum and reddendum                     |  | 4                                                                  
|3          |  | Tenant's covenants                                    |  | 5                                                                  
|4          |  | Landlord's covenants                                  |  | 5                                                                  
|5          |  | Company's covenants                                   |  | 5                                                                  
|6          |  | Proviso agreement and declaration                     |  | 5                                                                  
|           |  | 6.1                                                   |  | Forfeiture                                                         
|           |  | 6.2                                                   |  | Notices                                                            
|           |  | 6.3                                                   |  | Rent abatement                                                     
|           |  | 6.4                                                   |  | Part II Landlord and Tenant Act 1954                               
|           |  | 6.5                                                   |  | Warranties                                                         
|           |  | 6.6                                                   |  | Landlord's powers to deal with the Landlord's Neighbouring Premises
|           |  | 6.7                                                   |  | Arbitration                                                        
|           |  | 6.8                                                   |  | Landlord's obligations                                             
|           |  | 6.9                                                   |  | Value added tax                                                    
|           |  | 6.10                                                  |  | Reference to Rights                                                
|           |  | 6.11                                                  |  | References to Consents                                             
|           |  | 6.12                                                  |  | References to Rights of Entry                                      
|           |  | 6.13                                                  |  | Third Party Rights                                                 
|7          |  | Surety's covenant                                     |  | 8                                                                  
|8          |  | Personal Rent Abatement                               |  | 8                                                                  
|Schedule 1 |  | 10                                                   
|           |  | Part 1                                                |  | 10                                                                 
|           |  | The property included in this demise                  |  | 10                                                                 
|           |  | Part 2                                                |  | 10                                                                 
|1          |  | Right to services                                     |  | 10                                                                 
|2          |  | Right of way                                          |  | 10                                                                 
|3          |  | Right to support                                      |  | 10                                                                 
|Schedule 2 |  | 11                                                   
|           |  | Part 1                                                |  | 11                                                                 
|           |  | Exceptions and reservations in favour of the Landlord |  | 11                                                                 
|1          |  | Right to light and air                                |  | 11                                                                 
|2          |  | Right to enter to cultivate                           |  | 11                                                                 
|3          |  | Right to restrict access                              |  | 11                                                                 
|4          |  | Right to services                                     |  | 11                                                                 
|           |  | Part 2                                                |  | 11                                                                 

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|           |  | Existing Encumbrances                                         |  | 11
|---------- |  | ------------------------------------------------------------- |  | --
|Schedule 3 |  | 12                                                           
|           |  | The rents payable by the Tenant                               |  | 12
|           |  | Part 1Rents payable quarterly                                |  | 12
|1          |  | Definitions                                                   |  | 13
|2          |  | The rent review                                               |  | 13
|3          |  | Memorandum of agreement as to rent                            |  | 13
|4          |  | Where assessment of rent delayed                              |  | 13
|5          |  | Intermediate rent periods                                     |  | 13
|           |  | Part 2Rents payable upon demand                              |  | 14
|1          |  | Insurance Rent                                                |  | 14
|2          |  | Rent for common parts                                         |  | 14
|3          |  | Interest on arrears                                           |  | 14
|4          |  | Insurance excess                                              |  | 14
|           |  | Part 3                                                        |  | 14
|           |  | Provisions and obligations relating to the Service Rent       |  | 14
|Schedule 4 |  | 20                                                           
|           |  | Tenant's covenants                                            |  | 20
|1          |  | To pay rent                                                   |  | 20
|2          |  | To pay outgoings                                              |  | 20
|3          |  | To repair and decorate                                        |  | 20
|4          |  | Not to make alterations                                       |  | 21
|5          |  | To permit entry                                               |  | 22
|6          |  | To repair on notice                                           |  | 22
|7          |  | To pay Landlord's costs                                       |  | 22
|8          |  | As to use and safety                                          |  | 23
|9          |  | Not to use for unlawful or illegal purposes or cause nuisance |  | 24
|10         |  | Not to reside                                                 |  | 24
|11         |  | As to user                                                    |  | 24
|12         |  | To keep open and security                                     |  | 25
|13         |  | Displays and advertisements                                   |  | 25
|14         |  | To keep clean                                                 |  | 25
|15         |  | To comply with Legal Obligations and give notice              |  | 25
|16         |  | To comply with the Planning Acts                              |  | 26
|17         |  | Insurance                                                     |  | 26
|18         |  | To indemnify                                                  |  | 27
|19         |  | Dealings with the Premises                                    |  | 28
|20         |  | To give notice of assignments, devolutions etc.               |  | 30

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|21         |  | As to loss or acquisition of easements                     |  | 30
|---------- |  | ---------------------------------------------------------- |  | --
|22         |  | To produce plans/documents                                 |  | 31
|23         |  | Not to interfere with reserved rights                      |  | 31
|24         |  | To permit entry for reletting etc.                         |  | 31
|25         |  | To yield up                                                |  | 31
|26         |  | New surety                                                 |  | 31
|27         |  | As to value added tax                                      |  | 31
|28         |  | As to maintenance contracts                                |  | 32
|29         |  | Statutory acquisitions                                     |  | 32
|30         |  | Fire fighting appliances                                   |  | 32
|31         |  | Existing Encumbrances                                      |  | 33
|32         |  | Not to obstruct                                            |  | 33
|33         |  | To comply with regulations                                 |  | 33
|34         |  | To comply with Planning Agreement and planning permissions |  | 33
|35         |  | To pay cost of damage                                      |  | 33
|36         |  | To permit access to the Company                            |  | 33
|37         |  | Costs                                                      |  | 33
|Schedule 5 |  | 34                                                        
|           |  | Landlord's covenants                                       |  | 34
|1          |  | As to quiet enjoyment                                      |  | 34
|2          |  | To insure and reinstate                                    |  | 34
|3          |  | Duty to Mitigate                                           |  | 34
|Schedule 6 |  | 35                                                        
|           |  | Surety's covenants and agreements                          |  | 35
|1          |  | Covenants by Surety                                        |  | 35
|2          |  | Agreements by Surety                                       |  | 35
|Schedule 7 |  | 37                                                        
|           |  | Guarantee Agreement                                        |  | 37
|1          |  | Definitions and interpretation                             |  | 37
|2          |  | Guarantee                                                  |  | 37
|3          |  | New lease                                                  |  | 38
|4          |  | Security taken by Guarantor                                |  | 39
|5          |  | Limitation on Guarantor's liability                        |  | 39
|6          |  | Joint and several Guarantors                               |  | 39

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THIS LEASEis made on            2001BETWEEN:

NOW THIS LEASE WITNESSETHas follows:

1   Definitions and Interpretation



1

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2

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3

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2   The demise habendum and reddendum

all
such payments to be made without any deduction

4

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3   Tenant's covenants

4   Landlord's covenants

5   Company's covenants

6   Proviso agreement and declaration

Without
prejudice to any other rights of the Landlord if:



5

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Any
notice under this Lease shall be in writing and any notice







6

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7

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7   Surety's covenant

8   Personal Rent Abatement

8

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Column 1

Column 2£1000,000

1st Year of the Term£75,000

2nd Year of the Term£50,000

3rd Year of the Term£25,000

4th Year of the Term




9

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Schedule 1

Part 1
The property included in this demise

ALL THATpiece or parcel of land forming part of Cambridge Science Park and known as Unit 334 as the same is
more particularly delineated on Plan 1 and thereon edged red and for the purpose of identification only delineated on Plan 2 and thereon edged green together with the buildings standing thereon or on
some part thereof

Part 2

1   Right to services

2   Right of way

3   Right to support

10

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Schedule 2

Part 1
Exceptions and reservations in favour of the Landlord

1   Right to light and air

2   Right to enter to cultivate

3   Right to restrict access

4   Right to services

Part 2
Existing Encumbrances

11

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Schedule 3

The rents payable by the Tenant
Part 1Rents payable quarterly

1   Definitions



12

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2   The rent review



3   Memorandum of agreement as to rent

4   Where assessment of rent delayed

5   Intermediate rent periods

13

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Part 2Rents payable upon demand

1   Insurance Rent

2   Rent for common parts

3   Interest on arrears

4   Insurance excess

Part 3
Provisions and obligations relating to the Service Rent

14

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15

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16

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17

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18

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19

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Schedule 4

Tenant's covenants

1   To pay rent

2   To pay outgoings

3   To repair and decorate





20

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4   Not to make alterations



21

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5   To permit entry



6   To repair on notice

7   To pay Landlord's costs

22

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8   As to use and safety

23

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9   Not to use for unlawful or illegal purposes or cause nuisance

10  Not to reside

11  As to user

24

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12  To keep open and security

13  Displays and advertisements

14  To keep clean

15  To comply with Legal Obligations and give notice

25

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16  To comply with the Planning Acts

17  Insurance

26

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18  To indemnify





27

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19  Dealings with the Premises

28

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29

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20  To give notice of assignments, devolutions etc.

21  As to loss or acquisition of easements

30

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22  To produce plans/documents

23  Not to interfere with reserved rights

24  To permit entry for reletting etc.

25  To yield up

26  New surety



27  As to value added tax

31

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28  As to maintenance contracts

29  Statutory acquisitions

30  Fire fighting appliances

32

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31  Existing Encumbrances

32  Not to obstruct

33  To comply with regulations

34  To comply with Planning Agreement and planning permissions



35  To pay cost of damage

36  To permit access to the Company

37  Costs

33

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Schedule 5

Landlord's covenants

1   As to quiet enjoyment

2   To insure and reinstate

3   Duty to Mitigate

34

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Schedule 6

Surety's covenants and agreements

1   Covenants by Surety

2   Agreements by Surety

35

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36

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Schedule 7

Guarantee Agreement

THIS DEEDdated            is madeBETWEEN:

("the Guarantor")

("the Landlord")

1   Definitions and interpretation



2   Guarantee

37

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3   New lease

38

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4   Security taken by Guarantor

5   Limitation on Guarantor's liability

6   Joint and several Guarantors

39

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[Executed
by the Guarantor and the Landlord as a deed]

|                                                                                                                |  |        
|--------------------------------------------------------------------------------------------------------------- |  | -------
|The common seal of THE MASTER
FELLOWS AND SCHOLARS OF
TRINITY COLLEGE CAMBRIDGE was
affixed in the presence of: |  | )
)
)
)
|                                                                                                                |  |        
|                                                                                                                |  |        
|Senior Bursar                                                                                                   |  |        
|                                                                                                                |  |        
|Junior Bursar                                                                                                   |  |        
|                                                                                                                |  |        
|                                                                                                                |  |        
|Signed as a deed by TRINITY COLLEGE
(CSP) LIMITED acting by a director and
its secretary or two directors       |  | )
)    
|                                                                                                                |  |        
|                                                                                                                |  |        
|Director                                                                                                        |  |        
|                                                                                                                |  |        
|Director/Secretary                                                                                              |  |        
|                                                                                                                |  |        
|                                                                                                                |  |        
|The common seal of ACCELRYS
LIMITED was affixed in thepresence of:                                              |  | )
)
)  
|                                                                                                                |  |        
|                                                                                                                |  |        
|Director                                                                                                        |  |        
|                                                                                                                |  |        
|Secretary                                                                                                       |  |        
|                                                                                                                |  |        
|                                                                                                                |  |        
|Signed as a deed by ACCELRYS INC
acting by a its authorised signatories                                         |  | )      
|                                                                                                                |  |        
|                                                                                                                |  |        
|Duly Authorised Signatory                                                                                       |  |        
|                                                                                                                |  |        
|Duly Authorised Signatory                                                                                       |  |        

40

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