### HOPGUARD **® II**  **For use in beehive s**  **to control Varroa**  **m ites**  **( Varroa destructor**  **) o**  **n h**  **oney bees**  **ACTIVE INGREDIENTS:** BY WEIGHT

Potassium Salt s of Hop Beta Acids ............ ............... ... 16.0 % **OTHER INGREDIENTS**  **:** ... ..................................................... 84.0% TOTAL 100.0% **KEEP OUT OF REACH OF CHILDREN**



## DANGER **PRECAUTIONARY STATEMENTS Hazards to Humans and Dom**  **estic Animals** Danger : Corrosive. Causes irreversible eye damage. Do not get in eyes or on clothing. Wear (specify appropriate protective eyewear such as goggles, face shield, or safety glasses). 

### Wash thoroughl y with soap and water after handl ing and b ef ore eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse. 

# FIRST **AI D** 

. 

### IF IN EYES: Hold eyelids open and flush with a steady, gentle stre am of water for 15 - 20 minutes. Remove contact lens es, if prese nt, af ter the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for advice **IF ON SKIN OR** Take off contaminated clothing. **CLOTHING** : Rinse skin immediately with plenty of water for 15 - 20 minutes.

Call a pois on control center or doctor for further treatment advice. **IF SWALLOWED** 

### : Call a poison control center or doctor immediately for treatment advice.

Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by poi son control center or doctor. Do not give anything by mouth to an unconscious person. 

### Have the product container or label with you when calling a poison control center or doctor, or going for treatment. You may also contact 1 - 800 - 858 - 7378 for emergency medical treatment For general information on product use, etc., call the National Pesticides Information Center at 1 - 800 - 858 - 7378. For emergencies, call the poison contro l center 1 - 8 00 - 222 - 1222. Note to Physician: “Probable mucosal damage may contraindicate the use of gastric lavage”. 

### S ee label back panel for additional precautionary statements. EPA Registration Number 8 3 623 - E EPA Establishment Number 61671 - MN - 001 **NET CONTENTS**Each HopGuard® kit contains 24 cardboard strips. Each strip is folded in half and contains 4.0 grams of

potassium salt s of hop beta acids, and the kit contains 96 grams (3.4 ounces) of potassium salt s of hop beta acids. **Manufactured by:** BetaTec Hop Products, Inc., A Division of John I. Haas, Inc., 1600 River Roa d, Yakima, WA 9890 2 

### PERSONAL **PROTECTION EQUIPMENT**  **(PPE) :**  Applicators and other handlers must wear appropriate protective eyewear, such as face shield or goggles long sleeved shirt and long pants, waterproof gloves and shoes plus socks.

**D IRECTIONS FOR USE**  Bee Package - Cut strips in half. Strips must be applied at the rate of three - half strips per 2 or 3 lb. package of adult worker bees. Attach three - half strips to the top of package so that the strips are hanging within the package. Place bees in the package after the strips are attached. The bees should remain in contact with the strips for at least 48 hours. Colony- Strips must be applied at the rate of one strip per five deep combs covered with bees in each brood super or for example two strips per ten frame brood super (chamber) when all combs are covered with bees. Strips are to be placed only in the brood chamber (not in the honey super). Folded strips must be opened and hung over one of the center brood frames near the middle of the frame with one - half of the strip on each side of the frame. If using a second strip, apply it to an adjacent center frame about four inches away from the first strip. Strips must be placed hanging between frames, and within the colony cluster, and not lai d on top of the frames. Do not lay the strips on top of the frames. Leave strips in the colony for 30 days. Retreat as necessary, up to 3 times per year. A maximum of three applications per year ( 6 strips or approximately 24 grams of potassium salts of hop beta a cids) per ten frame brood super (chamber) is allowed. This limit includes all applications to the package(if applicable) and to the colony. Application timing (usually during spring , summer, and fall) should be based on levels of Varroa mite obs erved in the colony
. Users m ust not take honey and wax from the brood chambers, only from the honey supers. For optimal results, apply HopGuard **®** II when little to no brood is present in the hive. **RESISTANCE MANAGEMENT** Varroa mite populations can become resistant to pesticides. Resistance development is affected by both the frequency of application and rate/dose of application. After an applicati on, the more susceptible pests die and the less susceptible ones survive , mate with other survivors , and reprodu ce. Most of the ensuing offspring inherit the parental resistance. Additional applications continue to kill only the remaining, unsusceptible individuals. Continued relian ce on a single class of miticide or miticide with the same mode of action will select for resistant individuals which will dominate the mite population in subsequent generations. In order to prevent resistance development and to maintain the usefulness of individual pesticides the adoption of an appropriate resistance management strategy is vital. The Mode of Action (MOA) for hop beta acids is undefined at this time: howeve r, it may cause death by asphyxiation by penetration of the pest's thin exoskeleton. To delay resistance: • When possible, rotate the use of miticides to reduce selecti on pressure as compared to repeatedly using the same p rodu ct, mode of action or chemical class. If multiple applications are required, use a different mode of action each time before returning to a previously - used one. 

### USER SAFETY RECOMMENDATIONS: Users must :

 Wa sh hands before eating, drinking, chewing gum, using tobacco or using the toilet.

 Remove clothing immediately if pesticide gets inside. Then wash th oroughly and put on clean clothing.

 Remove PPE immediately after handling this product. Wa sh the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing.• Base rniticide use on Integra ted Pest Management (IPM). This includes proper pest identification, monitoring for

locality, specific economic threshold and economic injury levels, record keepi ng, and utilizing all available control practices (cultural. biological and chemical). • Maximize efficacy by following all label instructions including dosage and timing of application. • Continually monitor treated populations for development of miticide resistance and report suspected res istance to l ocal extension specialists. • Contact your local extension specialist for additional pesticide resistance/management recommendations and /or !PM recommendations for your specific location. • For further information or to report suspected resistance contact your local extension specialist. • Remove strips if still in hive after 30 days. **RESTRICTIONS** • For in - hive use only. • Maximum rate = 2 strips per brood chamber per application (i.e. one strip per five frames covered with bees). 

### • Remove remaining strip(s) after 30 days. • Do not use Hop Guard® II more than 3 times per year. **STORAGE AND DISPOSA L**  Unused strips should be stored in a tightly sealed, cool, dark area. Unused, unregistered product must either be returned to the manufacturer or distributor in unopened containers or disposed of i n accordance with the Resource Conservation Recovery Act
.