Page 7 of 25 

Appendix A 

Occupational and Residential Exposure and Risk Calculations 
Page 8 of 25 

Table 1 – Short-/Intermediate-term Inhalation MOEs for Occupational Handlers Applying Spa

Exposure Scenario 

Inhalation 

Unit 

ExposureA

(μg/lb ai) 

Application RateB Amount Sprayed per Day lb ai handled per day 

(

Aerosol can application 1300 0.35% ai 6 cansC 0.015 

A. Unit Exposure values are from PHED. B. Application rates are from EPA Reg. No. 4822-513. C. Screening level estimate based upon professional judgment. 

D. Inhalation dose (mg/kg/day) = [unit exposure (ug/lb ai) * 0.001 mg/ g * lb ai handled per day)] / Body weight (70 kg). E. MOE = NOAEL (3.5 mg/kg/day) / Dose 

Table 2 – Inhalation MOEs for Residential Handlers

Exposure Scenario 

Inhalation Unit 

ExposureA

(μg/lb ai) 

Application RateB Amount Sprayed 

per Day lb ai handled per dayC

Aerosol can application 1300 0.35% ai 1 can 0.0025 

A. Unit exposures are from PHED or proprietary data. Respiratory protection is not considered for residential exposure assessments. B. Application rates are from EPA Reg. No. 4822-513. C. Based upon ExpoSAC Policy 12. 

D. Inhalation dose (mg/kg/day) = [Unit Exposure (ug/lb ai) * 0.001 mg/g * lb ai handled per day)] / Body weight (70 kg) E. MOE = NOAEL (3.5 mg/kg/day) /Dose 
Page 9 of 25 

Table 3 – Incidental Oral Ingestion Risks from Hand-to-Mouth Activity by Toddlers Playing on In

Application 

Type 

Indoor Surface ResidueA

(μg/cm2) Indoor Surface Hand Transfer EfficiencyB Daily Ora

(mg/kg

Carpet 8.0% 0.14

Aerosol can 16.9 

Vinyl 11.0% 0.09

A. EPA Reg. No. 4822-153: 16 oz can of 0.35% tetramethrin applied to 100 ft2

B. Based upon the NDETF Volume 13 (MRID 46188613). C. Daily Oral Dose (mg/day) = (ISR * HTE * SEF * SA * Freq * ED * 0.001 mg/ug) / BW 

where: ISR = Indoor Surface Residue (ug/cm2) 

 HTE = Hand Transfer Efficiency  SEF = Saliva Extraction Factor (50%)  SA = Surface area of hand mouthed (20 cm2) 

 Freq = Frequency of Hand to Mouth Events (20 events/hour for short term)  ED = Exposure Duration = 4 hours/day for vinyl floors and 8 hours/day for carpeted floors  BW = 15 kg for toddler 

D. MOE = NOAEL (25 mg/kg/day for short term exposures)/Daily Oral Dose (mg/kg/day) 

Table 4 – Inhalation Risks to Residents following Indoor Space Spray Applications

NDETF Study Application Rate 

(mg/m3)A

Adjusted 

Application Rate 

(mg/m3)B

Measured Breathing Zone 

ConcentrationC

(mg/m3) 

Adjusted Breathing 

Zone ConcentrationD

(mg/m3) 

Expos

Individ

Adul

0.80 0.56 0.022 0.015 Child 

A. Based upon aerosol can application of 9.31 grams of 0.50% pyrethrins to a room with an internal volume of 58 cubic meters (NDETF 

B. Application rate from NDETF study (Vol 18) adjusted for 0.35% tetramethrin aerosol product (4822-513): 

Adj. App Rate = [NDETF Rate * Tetramethrin Product Conc. (0.35%)] / NDETF Product Conc. (0.5%) 

C. From NDETF Vol. 18: 2 hour TWA at the 5 foot sampler height for time t = 0 to time t = 120 minutes after application (adjusted for 

D. Adj. Breathing Zone Conc. = [Adjusted App. Rate/NDETF Study Application Rate] * Measured Breathing Zone Concentration E. Inhalation Dose = (Adj. BZC * BR * ED) / BW 

Where: 

 Adj. BZC = Adjusted Breathing Zone Concentration (mg/m3): measured air concentration from NDETF Vol. 18 adjust

 BR = Breathing rate for adult or child (m3/hr) (1.0 m3/hr adult, 0.7 m3/hr child) 

 BW = 70 kg for adult; 15 kg for toddler 

 ED = Exposure Duration (8 hr/day) F. Inhalation MOE = NOAEL (3.5 mg/kg/day)/ Inhalation Dose 
Page 10 of 25 

Appendix B 

CARES Inputs 
Page 11 of 25 

APPENDIX B INPUTS FOR “PROBABILISTIC A” Residential Wizard SettingsName: Valent Tetramethrin Author: Muhilan Pandian Date: Thursday, March 20, 2008 Comments: Tetramethrin CARES Assessment - March/April 2008 Scenarios & Methods Scenario During/Post Route Method Indoor Treatment - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Indoor Treatment - 1 During Inhalation Inhalation 102: Unit Exposure, Amount of Formulation 

Used 

Indoor Treatment - 1 Post Inhalation Inhalation 103: Air Concentration, SpecifiedScenarios & Products Scenario Product CAS Product Probability Indoor Treatment P102;Indoor Spray - 

Aerosol Can 

Tetramethrin 1

Scenario Probabilities Scenario Scenario 

Probability 

Market Share (Chemical Probability) 

Indoor Treatment - 1 1 1Event Allocation Monthly Probabilities (Jan-Jun) Scenario Jan Feb Mar Apr May Jun Indoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Monthly Probabilities (Jul-Dec) Scenario Jul Aug Sep Oct Nov Dec Indoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Day of Week Probabilities Scenario Sun Mon Tue Wed Thr Fri Sat Indoor Treatment - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429
Page 12 of 25 

Annual Use & Treatment Interval Scenario # Uses Treatment Interval (Days) Indoor Treatment - 1 Single (10) Single (10)Co-Occurrence Scenario 1 Scenario 2 Co-Occurence Indoor Treatment - 1 Indoor Treatment - 1 0INPUTS Scenario-Specific Group Variable Name Unit Value Indoor Treatment - 1 Exposure Duration (Adult) hr/day Uniform (1,8) Indoor Treatment - 1 Exposure Duration (Child) hr/day Uniform (1,8)Method-Specific Group Variable Name Unit Value Indoor Treatment - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,13,26) 

Indoor Treatment - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.2,0.5) Indoor Treatment - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,5) Indoor Treatment - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 

(1,7,20)

Product-specific Group Variable Name Unit Value P102; Indoor Spray - Aerosol Can Application (AI per Area Treated) mg/cm2 Single (0.017) P102; Indoor Spray - Aerosol Can Fraction AI Dislodgeable in Surface unitless LogNormal 

(0.032,0.018,0.01,0.19) 

P102; Indoor Spray - Aerosol Can HalfLife day Single (7) P102; Indoor Spray - Aerosol Can Application (Amount of AI Used) kg/m3 Single (2.5) P102; Indoor Spray - Aerosol Can Amount of Formulation Used (Volume) m3 Single 

(0.000454) 

P102; Indoor Spray - Aerosol Can Unit Exposure (Inhalation) mg/lb Single (1.3) P102; Indoor Spray - Aerosol Can Concentration of AI in Air mg/m3 Uniform 

(0.00022,0.011)
Page 13 of 25 

APPENDIX B INPUTS FOR “PROBABILISTIC B” Residential Wizard SettingsName: Valent Tetramethrin Author: Muhilan Pandian Date: Thursday, March 20, 2008 Comments: Tetramethrin CARES Assessment - March/April 2008 Scenarios & Methods Scenario During/Post Route Method Pet Care - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Outdoor Fogger Use - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Outdoor Fogger Use - 1 Post Inhalation Inhalation 104: Air Concentration, Calculated Indoor Fogger Use - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Indoor Treatment - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Indoor Treatment - 1 During Inhalation Inhalation 102: Unit Exposure, Amount of Formulation 

Used 

Indoor Treatment - 1 Post Inhalation Inhalation 103: Air Concentration, Specified Custom - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Custom - 1 Post Inhalation Inhalation 104: Air Concentration, CalculatedScenarios & Products Scenario Product CAS Product Probability Outdoor Fogger Use P101;Outdoor Total 

Release Fogger 

Tetramethrin 1 

Indoor Treatment P102;Indoor Spray - 

Aerosol Can 

Tetramethrin 1 

Pet Care P103;Pets - Aerosol 

Can 

Tetramethrin 1 

Indoor Fogger Use P104;Indoor Total 

Release Fogger 

Tetramethrin 1 

Indoor Treatment P105;Indoor Spray - 

RTU 

Tetramethrin 0 

Custom P106;Outdoor Spray - 

Handheld Fogger 

Tetramethrin 0.5 

Custom P107;Outdoor Spray - 

Aerosol Can 

Tetramethrin 0.5

Scenario Probabilities 
Page 14 of 25 

Scenario Scenario 

Probability 

Market Share (Chemical Probability) 

Pet Care - 1 0 0 Outdoor Fogger Use - 1 0 0 Indoor Fogger Use - 1 0 0 Indoor Treatment - 1 1 1 Custom - 1 0 0Event Allocation Monthly Probabilities (Jan-Jun) Scenario Jan Feb Mar Apr May Jun Pet Care - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Outdoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Indoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Indoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Custom - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Monthly Probabilities (Jul-Dec) Scenario Jul Aug Sep Oct Nov Dec Pet Care - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Outdoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Indoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Indoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Custom - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Day of Week Probabilities Scenario Sun Mon Tue Wed Thr Fri Sat Pet Care - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 Outdoor Fogger Use - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 Indoor Fogger Use - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 Indoor Treatment - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 Custom - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429Annual Use & Treatment Interval Scenario # Uses Treatment Interval (Days) Pet Care - 1 Single (10) Single (10) Outdoor Fogger Use - 1 Single (10) Single (10) Indoor Fogger Use - 1 Single (10) Single (10) Indoor Treatment - 1 Single (10) Single (10) Custom - 1 Single (10) Single (10)
Page 15 of 25 

Co-Occurrence Scenario 1 Scenario 2 Co-Occurence Pet Care - 1 Pet Care - 1 0 Pet Care - 1 Outdoor Fogger Use - 1 0 Pet Care - 1 Indoor Fogger Use - 1 0 Pet Care - 1 Indoor Treatment - 1 0 Pet Care - 1 Custom - 1 0 Outdoor Fogger Use - 1 Pet Care - 1 0 Outdoor Fogger Use - 1 Outdoor Fogger Use - 1 0 Outdoor Fogger Use - 1 Indoor Fogger Use - 1 0 Outdoor Fogger Use - 1 Indoor Treatment - 1 0 Outdoor Fogger Use - 1 Custom - 1 0 Indoor Fogger Use - 1 Pet Care - 1 0 Indoor Fogger Use - 1 Outdoor Fogger Use - 1 0 Indoor Fogger Use - 1 Indoor Fogger Use - 1 0 Indoor Fogger Use - 1 Indoor Treatment - 1 0 Indoor Fogger Use - 1 Custom - 1 0 Indoor Treatment - 1 Pet Care - 1 0 Indoor Treatment - 1 Outdoor Fogger Use - 1 0 Indoor Treatment - 1 Indoor Fogger Use - 1 0 Indoor Treatment - 1 Indoor Treatment - 1 0 Indoor Treatment - 1 Custom - 1 0 Custom - 1 Pet Care - 1 0 Custom - 1 Outdoor Fogger Use - 1 0 Custom - 1 Indoor Fogger Use - 1 0 Custom - 1 Indoor Treatment - 1 0 Custom - 1 Custom - 1 0INPUTS Scenario-Specific Group Variable Name Unit Value Outdoor Fogger Use - 1 Exposure Duration (Adult) hr/day Uniform (1,2) Outdoor Fogger Use - 1 Exposure Duration (Child) hr/day Percentile2 (interpolated) 

(0 0 5 0.083 25 0.75 50 0.9 75 2.4 90 3.5 100 3.5) 

Indoor Treatment - 1 Exposure Duration (Adult) hr/day Uniform (1,8) Indoor Treatment - 1 Exposure Duration (Child) hr/day Uniform (1,8) Custom - 1 Exposure Duration (Adult) hr/day Uniform (1,2) Custom - 1 Exposure Duration (Child) hr/day Percentile2 (interpolated) 
Page 16 of 25 

(0 0 5 0.083 25 0.75 50 0.9 75 2.4 90 3.5 100 3.5)

Method-Specific Group Variable Name Unit Value Pet Care - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,13,26) 

Pet Care - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.2,0.5) Pet Care - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Triangular 

(0.03,0.108,1.03) 

Pet Care - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 

(1,7,20) 

Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,6,26) 

Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.2,0.5) Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,2) Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 

(1,7,20) 

Outdoor Fogger Use - 1 ; Inhalation 104: Air Concentration, Calculated 

Dilution Factor (Indoor or Outdoor Air) unitless Single (0.01) 

Outdoor Fogger Use - 1 ; Inhalation 104: Air Concentration, Calculated 

Volume (Indoor or Outdoor) m3 Single (130.2) 

Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,13,26) 

Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.2,0.5) Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,5) Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 

(1,7,20) 

Indoor Treatment - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,13,26) 

Indoor Treatment - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.1,0.5) Indoor Treatment - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,4) Indoor Treatment - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 

(1,7,20) 

Custom - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,6,26) 

Custom - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.2,0.5) Custom - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,2) 
Page 17 of 25 

Custom - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 

(1,7,20) 

Custom - 1 ; Inhalation 104: Air Concentration, Calculated Dilution Factor (Indoor or Outdoor Air) unitless Single (0.01) Custom - 1 ; Inhalation 104: Air Concentration, Calculated Volume (Indoor or Outdoor) m3 Single (130.2)Product-specific Group Variable Name Unit Value P101; Outdoor Total Release Fogger Application (AI per Area Treated) kg/m2 Single (0.0001) P101; Outdoor Total Release Fogger Fraction AI Dislodgeable in Surface unitless Single (0.05) P101; Outdoor Total Release Fogger HalfLife day Single (0.00001) P101; Outdoor Total Release Fogger Amount of Formulation Used (Volume) cm3 Single (170) P101; Outdoor Total Release Fogger Fraction AI in Formulation unitless Single (0.0054) P101; Outdoor Total Release Fogger Density of Formulation g/cm3 Single (1) P102; Indoor Spray - Aerosol Can Application (AI per Area Treated) mg/cm2 Uniform 

(0.0085,0.017) 

P102; Indoor Spray - Aerosol Can Fraction AI Dislodgeable in Surface unitless LogNormal 

(0.032,0.018,0.01,0.19) 

P102; Indoor Spray - Aerosol Can HalfLife day Single (7) P102; Indoor Spray - Aerosol Can Application (Amount of AI Used) kg/m3 Single (2.5) P102; Indoor Spray - Aerosol Can Amount of Formulation Used (Volume) m3 Single 

(0.000454) 

P102; Indoor Spray - Aerosol Can Unit Exposure (Inhalation) mg/lb Single (1.3) P102; Indoor Spray - Aerosol Can Concentration of AI in Air mg/m3 Uniform 

(0.00022,0.011) 

P103; Pets - Aerosol Can Application (AI per Area Treated) mg/cm2 Single (0.024) P103; Pets - Aerosol Can Fraction AI Dislodgeable in Surface unitless Single (0.02) P103; Pets - Aerosol Can HalfLife day Single (0.00001) P104; Indoor Total Release Fogger Application (AI per Area Treated) mg/cm2 Single (0.00129) P104; Indoor Total Release Fogger Fraction AI Dislodgeable in Surface unitless LogNormal 

(0.032,0.018,0.01,0.19) 

P104; Indoor Total Release Fogger HalfLife day Single (0.00001) P105; Indoor Spray - RTU Application (AI per Area Treated) mg/cm2 Single (0.0051) P105; Indoor Spray - RTU Fraction AI Dislodgeable in Surface unitless LogNormal 

(0.032,0.018,0.01,0.19) 

P105; Indoor Spray - RTU HalfLife day Single (0.00001) P105; Indoor Spray - RTU Application (Amount of AI Used) lb/gal Single (0.02) P105; Indoor Spray - RTU Amount of Formulation Used (Volume) gal Single (1) P105; Indoor Spray - RTU Unit Exposure (Inhalation) mg/lb Single (0.123) P105; Indoor Spray - RTU Concentration of AI in Air mg/m3 Uniform 

(0.00022,0.011) 
Page 18 of 25 

P106; Outdoor Spray - Handheld Fogger Application (AI per Area Treated) mg/cm2 Single 

(0.000053) 

P106; Outdoor Spray - Handheld Fogger Fraction AI Dislodgeable in Surface unitless Single (0.05) P106; Outdoor Spray - Handheld Fogger HalfLife day Single (0.00001) P106; Outdoor Spray - Handheld Fogger Amount of Formulation Used (Volume) oz Single (1) P106; Outdoor Spray - Handheld Fogger Fraction AI in Formulation unitless Single (0.001) P106; Outdoor Spray - Handheld Fogger Density of Formulation g/cm3 Single (1) P107; Outdoor Spray - Aerosol Can Application (AI per Area Treated) mg/cm2 Single (0.01) P107; Outdoor Spray - Aerosol Can Fraction AI Dislodgeable in Surface unitless Single (0.05) P107; Outdoor Spray - Aerosol Can HalfLife day Single (0.00001) P107; Outdoor Spray - Aerosol Can Amount of Formulation Used (Volume) cm3 Single (170) P107; Outdoor Spray - Aerosol Can Fraction AI in Formulation unitless Single (0.0054) P107; Outdoor Spray - Aerosol Can Density of Formulation g/cm3 Single (1)
Page 19 of 25 

APPENDIX B INPUTS FOR “PROBABILISTIC C” Residential Wizard SettingsName: Valent Tetramethrin Author: Muhilan Pandian Date: Thursday, March 20, 2008 Comments: Tetramethrin CARES Assessment - March/April 2008 Scenarios & Methods Scenario During/Post Route Method Pet Care - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Outdoor Fogger Use - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Outdoor Fogger Use - 1 Post Inhalation Inhalation 104: Air Concentration, Calculated Indoor Fogger Use - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Indoor Treatment - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Indoor Treatment - 1 During Inhalation Inhalation 102: Unit Exposure, Amount of Formulation 

Used 

Indoor Treatment - 1 Post Inhalation Inhalation 103: Air Concentration, Specified Custom - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOP Custom - 1 Post Inhalation Inhalation 104: Air Concentration, CalculatedScenarios & Products Scenario Product CAS Product Probability Outdoor Fogger Use P101;Outdoor Total 

Release Fogger 

Tetramethrin 1 

Indoor Treatment P102;Indoor Spray - 

Aerosol Can 

Tetramethrin 1 

Pet Care P103;Pets - Aerosol 

Can 

Tetramethrin 1 

Indoor Fogger Use P104;Indoor Total 

Release Fogger 

Tetramethrin 1 

Indoor Treatment P105;Indoor Spray - 

RTU 

Tetramethrin 0 

Custom P106;Outdoor Spray - 

Handheld Fogger 

Tetramethrin 0.5 

Custom P107;Outdoor Spray - 

Aerosol Can 

Tetramethrin 0.5

Scenario Probabilities Scenario Scenario Market Share (Chemical 
Page 20 of 25 

Probability Probability) 

Pet Care - 1 0 0 Outdoor Fogger Use - 1 0 0 Indoor Fogger Use - 1 0 0 Indoor Treatment - 1 1 1 Custom - 1 0 0Event Allocation Monthly Probabilities (Jan-Jun) Scenario Jan Feb Mar Apr May Jun Pet Care - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Outdoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Indoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Indoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Custom - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Monthly Probabilities (Jul-Dec) Scenario Jul Aug Sep Oct Nov Dec Pet Care - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Outdoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Indoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Indoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833 Custom - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Day of Week Probabilities Scenario Sun Mon Tue Wed Thr Fri Sat Pet Care - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 Outdoor Fogger Use - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 Indoor Fogger Use - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 Indoor Treatment - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 Custom - 1 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429 0.1429Annual Use & Treatment Interval Scenario # Uses Treatment Interval (Days) Pet Care - 1 Single (10) Single (10) Outdoor Fogger Use - 1 Single (10) Single (10) Indoor Fogger Use - 1 Single (10) Single (10) Indoor Treatment - 1 Single (10) Single (10) Custom - 1 Single (10) Single (10)
Page 21 of 25 

Co-Occurrence Scenario 1 Scenario 2 Co-Occurence Pet Care - 1 Pet Care - 1 0 Pet Care - 1 Outdoor Fogger Use - 1 0 Pet Care - 1 Indoor Fogger Use - 1 0 Pet Care - 1 Indoor Treatment - 1 0 Pet Care - 1 Custom - 1 0 Outdoor Fogger Use - 1 Pet Care - 1 0 Outdoor Fogger Use - 1 Outdoor Fogger Use - 1 0 Outdoor Fogger Use - 1 Indoor Fogger Use - 1 0 Outdoor Fogger Use - 1 Indoor Treatment - 1 0 Outdoor Fogger Use - 1 Custom - 1 0 Indoor Fogger Use - 1 Pet Care - 1 0 Indoor Fogger Use - 1 Outdoor Fogger Use - 1 0 Indoor Fogger Use - 1 Indoor Fogger Use - 1 0 Indoor Fogger Use - 1 Indoor Treatment - 1 0 Indoor Fogger Use - 1 Custom - 1 0 Indoor Treatment - 1 Pet Care - 1 0 Indoor Treatment - 1 Outdoor Fogger Use - 1 0 Indoor Treatment - 1 Indoor Fogger Use - 1 0 Indoor Treatment - 1 Indoor Treatment - 1 0 Indoor Treatment - 1 Custom - 1 0 Custom - 1 Pet Care - 1 0 Custom - 1 Outdoor Fogger Use - 1 0 Custom - 1 Indoor Fogger Use - 1 0 Custom - 1 Indoor Treatment - 1 0 Custom - 1 Custom - 1 0INPUTS Scenario-Specific Group Variable Name Unit Value Outdoor Fogger Use - 1 Exposure Duration (Adult) hr/day Uniform (1,2) Outdoor Fogger Use - 1 Exposure Duration (Child) hr/day Percentile2 (interpolated) 

(0 0 5 0.083 25 0.75 50 0.9 75 2.4 90 3.5 100 3.5) 

Indoor Treatment - 1 Exposure Duration (Adult) hr/day Uniform (1,8) Indoor Treatment - 1 Exposure Duration (Child) hr/day Uniform (1,8) Custom - 1 Exposure Duration (Adult) hr/day Uniform (1,2) Custom - 1 Exposure Duration (Child) hr/day Percentile2 (interpolated) 

(0 0 5 0.083 25 0.75 50 0.9 
Page 22 of 25 

75 2.4 90 3.5 100 3.5)

Method-Specific Group Variable Name Unit Value Pet Care - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,13,26) 

Pet Care - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.2,0.5) Pet Care - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Triangular 

(0.03,0.108,1.03) 

Pet Care - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 

(1,7,20) 

Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,6,26) 

Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.2,0.5) Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,2) Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 

(1,7,20) 

Outdoor Fogger Use - 1 ; Inhalation 104: Air Concentration, Calculated 

Dilution Factor (Indoor or Outdoor Air) unitless Single (0.01) 

Outdoor Fogger Use - 1 ; Inhalation 104: Air Concentration, Calculated 

Volume (Indoor or Outdoor) m3 Single (130.2) 

Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,13,26) 

Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.2,0.5) Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,5) Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 

(1,7,20) 

Indoor Treatment - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,13,26) 

Indoor Treatment - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.2,0.5) Indoor Treatment - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,5) Indoor Treatment - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 

(1,7,20) 

Custom - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular 

(1,6,26) 

Custom - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth) unitless Uniform (0.2,0.5) Custom - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,2) Custom - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular 
Page 23 of 25 

(1,7,20) 

Custom - 1 ; Inhalation 104: Air Concentration, Calculated Dilution Factor (Indoor or Outdoor Air) unitless Single (0.01) Custom - 1 ; Inhalation 104: Air Concentration, Calculated Volume (Indoor or Outdoor) m3 Single (130.2)Product-specific Group Variable Name Unit Value P101; Outdoor Total Release Fogger Application (AI per Area Treated) kg/m2 Single (0.0001) P101; Outdoor Total Release Fogger Fraction AI Dislodgeable in Surface unitless Single (0.05) P101; Outdoor Total Release Fogger HalfLife day Single (0.00001) P101; Outdoor Total Release Fogger Amount of Formulation Used (Volume) cm3 Single (170) P101; Outdoor Total Release Fogger Fraction AI in Formulation unitless Single (0.0054) P101; Outdoor Total Release Fogger Density of Formulation g/cm3 Single (1) P102; Indoor Spray - Aerosol Can Application (AI per Area Treated) mg/cm2 Uniform 

(0.0085,0.017) 

P102; Indoor Spray - Aerosol Can Fraction AI Dislodgeable in Surface unitless LogNormal 

(0.032,0.018,0.01,0.19) 

P102; Indoor Spray - Aerosol Can HalfLife day Single (7) P102; Indoor Spray - Aerosol Can Application (Amount of AI Used) kg/m3 Single (2.5) P102; Indoor Spray - Aerosol Can Amount of Formulation Used (Volume) m3 Single 

(0.000454) 

P102; Indoor Spray - Aerosol Can Unit Exposure (Inhalation) mg/lb Single (1.3) P102; Indoor Spray - Aerosol Can Concentration of AI in Air mg/m3 Uniform 

(0.00022,0.011) 

P103; Pets - Aerosol Can Application (AI per Area Treated) mg/cm2 Single (0.024) P103; Pets - Aerosol Can Fraction AI Dislodgeable in Surface unitless Single (0.02) P103; Pets - Aerosol Can HalfLife day Single (0.00001) P104; Indoor Total Release Fogger Application (AI per Area Treated) mg/cm2 Single (0.00129) P104; Indoor Total Release Fogger Fraction AI Dislodgeable in Surface unitless LogNormal 

(0.032,0.018,0.01,0.19) 

P104; Indoor Total Release Fogger HalfLife day Single (0.00001) P105; Indoor Spray - RTU Application (AI per Area Treated) mg/cm2 Single (0.0051) P105; Indoor Spray - RTU Fraction AI Dislodgeable in Surface unitless LogNormal 

(0.032,0.018,0.01,0.19) 

P105; Indoor Spray - RTU HalfLife day Single (0.00001) P105; Indoor Spray - RTU Application (Amount of AI Used) lb/gal Single (0.02) P105; Indoor Spray - RTU Amount of Formulation Used (Volume) gal Single (1) P105; Indoor Spray - RTU Unit Exposure (Inhalation) mg/lb Single (0.123) P105; Indoor Spray - RTU Concentration of AI in Air mg/m3 Uniform 

(0.00022,0.011) 

P106; Outdoor Spray - Handheld Fogger Application (AI per Area Treated) mg/cm2 Single 
Page 24 of 25 

(0.000053) 

P106; Outdoor Spray - Handheld Fogger Fraction AI Dislodgeable in Surface unitless Single (0.05) P106; Outdoor Spray - Handheld Fogger HalfLife day Single (0.00001) P106; Outdoor Spray - Handheld Fogger Amount of Formulation Used (Volume) oz Single (1) P106; Outdoor Spray - Handheld Fogger Fraction AI in Formulation unitless Single (0.001) P106; Outdoor Spray - Handheld Fogger Density of Formulation g/cm3 Single (1) P107; Outdoor Spray - Aerosol Can Application (AI per Area Treated) mg/cm2 Single (0.01) P107; Outdoor Spray - Aerosol Can Fraction AI Dislodgeable in Surface unitless Single (0.05) P107; Outdoor Spray - Aerosol Can HalfLife day Single (0.00001) P107; Outdoor Spray - Aerosol Can Amount of Formulation Used (Volume) cm3 Single (170) P107; Outdoor Spray - Aerosol Can Fraction AI in Formulation unitless Single (0.0054) P107; Outdoor Spray - Aerosol Can Density of Formulation g/cm3 Single (1)
Page 25 of 25 

Attachment 1 

Tetramethrin CARES Submission MRID 47713101