# Page 7 of 25 

# Appendix A

Occupational and Residential Ex posure and Risk CalculationsPage 8 of 25Table 1 – Short-/Intermediate-term Inhalation MOEsfor Occupational Handlers Applying Space SpraysExposure ScenarioInhalationUnitExposureA(μg/lb ai)Application RateBAmount Sprayedper Daylb ai handled per dayInhalationDoseD(mg/kg/day)InhalationMOEEAerosol can application 1300 0.35% ai6 cansC0.0150.000399000A.Unit Exposure values are from PHED.B.Application rates are from EPA Reg. No. 4822-513.C.Screening level estimate based upon professional judgment.D.Inhalation dose (mg/kg/day) = [unit exposure (ug/lb ai) * 0.001 mg/ g * lb ai handled per day)] / Body weight (70 kg).E.MOE = NOAEL (3.5 mg/kg/day) / DoseTable 2 – Inhalation MOEsfor Residential HandlersExposure ScenarioInhalation UnitExposureA(μg/lb ai)Application RateBAmount Sprayedper Daylb ai handled per dayCInhalationDoseD(mg/kg/day)InhalationMOEEAerosol can application 1300 0.35% ai1 can0.00250.00006554000A.Unit exposures are from PHED or proprietary data. Respiratory protection is not considered for residential exposure assessments.B.Application rates are from EPA Reg. No. 4822-513.C.Based upon ExpoSAC Policy 12.D.Inhalation dose (mg/kg/day) = [Unit Exposure (ug/lb ai) * 0.001 mg/g * lb ai handled per day)] / Body weight (70 kg)E.MOE = NOAEL (3.5 mg/kg/day) /DosePage 9 of 25Table 3 – Incidental Oral Ingestion Risks from Hand-to-Mouth Activityby Toddlers Playing on Indoor SurfacesApplicationTypeIndoor Surface ResidueA(μg/cm2)Indoor SurfaceHand TransferEfficiencyBDaily Oral DoseC(mg/kg/day)Incidental OralMOEDCarpet 8.0% 0.144 170Aerosol can 16.9Vinyl 11.0% 0.099 250A.EPA Reg. No. 4822-153: 16 oz can of 0.35% tetramethrin applied to 100 ft2B.Based upon the NDETF Volume 13 (MRID 46188613).C.Daily Oral Dose (mg/day) = (ISR * HTE * SEF * SA * Freq * ED * 0.001 mg/ug) / BWwhere: ISR = Indoor Surface Residue (ug/cm2)HTE = Hand Transfer EfficiencySEF = Saliva Extraction Factor (50%)SA = Surface area of hand mouthed (20 cm2)Freq = Frequency of Hand to Mouth Events (20 events/hour for short term)ED = Exposure Duration = 4 hours/day for vinyl floors and 8 hours/day for carpeted floorsBW = 15 kg for toddlerD.MOE = NOAEL (25 mg/kg/day for short term exposures)/Daily Oral Dose (mg/kg/day)Table 4 – Inhalation Risks to Residents following Indoor Space Spray ApplicationsNDETF Study Application Rate(mg/m3)AAdjustedApplication Rate(mg/m3)BMeasured Breathing ZoneConcentrationC(mg/m3)Adjusted BreathingZone ConcentrationD(mg/m3)ExposedIndividualDoseE(mg/kg/day)MOEFAdult 0.0018 20000.80 0.56 0.022 0.015Child 0.0057 610A.Based upon aerosol can application of 9.31 grams of 0.50% pyrethrins to a room with an internal volume of 58 cubic meters (NDETF Volume 18; MRID 46188618)B.Application rate from NDETF study (Vol 18) adjustedfor 0.35% tetramethrin aerosol product (4822-513):Adj. App Rate = [NDETF Rate * Tetramethrin Product Conc. (0.35%)] / NDETF Product Conc. (0.5%)C.From NDETF Vol. 18: 2 hour TWA at the 5 foot sampler heightfor time t = 0 to time t = 120 minutes after application (adjustedfor field recovery of 85 percent).D.Adj. Breathing Zone Conc. = [Adjusted App. Rate/NDETF Study Application Rate] * Measured Breathing Zone ConcentrationE.Inhalation Dose = (Adj. BZC * BR * ED) / BWWhere:Adj. BZC = Adjusted Breathing Zone Concentration (mg/m3): measured air concentration from NDETF Vol.18 adjusted to reflect the application rateBR = Breathing rate for adult or child (m3/hr) (1.0 m3/hr adult, 0.7 m3/hr child)BW = 70 kg for adult; 15 kg for toddlerED = Exposure Duration (8 hr/day)F.Inhalation MOE = NOAEL (3.5 mg/kg/day)/ Inhalation Dose

# Page 10 of 25 

# Appendix B

CARES InputsPage 11 of 25APPENDIX BINPUTS FOR “PROBABILISTIC A”Residential Wizard SettingsName: Valent TetramethrinAuthor: Muhilan PandianDate: Thursday, March 20, 2008Comments: Tetramethrin CARESAssessment - March/April 2008Scenarios & MethodsScenarioDuring/PostRouteMethodIndoor Treatment - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPIndoor Treatment - 1 During Inhalation Inhalation 102: Unit Exposure, Amount of FormulationUsedIndoor Treatment - 1 Post Inhalation Inhalation 103: Air Concentration, SpecifiedScenarios & ProductsScenarioProductCASProduct ProbabilityIndoor Treatment P102;Indoor Spray -Aerosol CanTetramethrin 1Scenario ProbabilitiesScenarioScenarioProbabilityMarket Share (ChemicalProbability)Indoor Treatment - 1 1 1Event AllocationMonthly Probabilities (Jan-Jun)ScenarioJanFebMarAprMayJunIndoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Monthly Probabilities (Jul-Dec)ScenarioJulAugSepOctNovDecIndoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Day of Week ProbabilitiesScenarioSunMonTueWedThrFriSatIndoor Treatment - 1 0.14290.1429 0.1429 0.1429 0.1429 0.1429 0.1429Page 12 of 25Annual Use & Treatment IntervalScenario# UsesTreatment Interval (Days)Indoor Treatment - 1 Single (10) Single (10)Co-OccurrenceScenario 1Scenario 2Co-OccurenceIndoor Treatment - 1 Indoor Treatment - 1 0INPUTSScenario-SpecificGroupVariable NameUnitValueIndoor Treatment - 1 Exposure Duration (Adult) hr/day Uniform (1,8)Indoor Treatment - 1 Exposure Duration (Child) hr/day Uniform (1,8)Method-SpecificGroupVariable NameUnitValueIndoor Treatment - 1 ; Ingestion 109: EPA SOP ContactFrequency (Hand-to-Mouth) event/hr Triangular(1,13,26)Indoor Treatment - 1 ; Ingestion 109: EPA SOPTransfer Efficiency per Contact (Hand-toMouth)unitlessUniform(0.2,0.5)Indoor Treatment - 1 ; Ingestion 109: EPA SOPExposure Durationhr/dayUniform (1,5)Indoor Treatment - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular(1,7,20)Product-specificGroupVariable NameUnitValueP102; Indoor Spray - Aerosol CanApplication (AI per Area Treated)mg/cm2Single (0.017)P102; Indoor Spray - Aerosol Can Fraction AI Dislodgeable in Surface unitless LogNormal(0.032,0.018,0.01,0.19)P102; Indoor Spray - Aerosol Can HalfLife day Single (7)P102; Indoor Spray - Aerosol Can Application (Amount of AI Used) kg/m3 Single (2.5)P102; Indoor Spray - Aerosol Can Amount ofFormulation Used (Volume) m3 Single(0.000454)P102; Indoor Spray - Aerosol Can Unit Exposure (Inhalation) mg/lb Single (1.3)P102; Indoor Spray - Aerosol Can Concentration of AI in Air mg/m3 Uniform(0.00022,0.011)Page 13 of 25APPENDIX BINPUTS FOR “PROBABILISTIC B”Residential Wizard SettingsName: Valent TetramethrinAuthor: Muhilan PandianDate: Thursday, March 20, 2008Comments: Tetramethrin CARESAssessment - March/April 2008Scenarios & MethodsScenarioDuring/PostRouteMethodPet Care - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPOutdoor Fogger Use - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPOutdoor Fogger Use - 1 Post Inhalation Inhalation 104: Air Concentration, CalculatedIndoor Fogger Use - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPIndoor Treatment - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPIndoor Treatment - 1 During Inhalation Inhalation 102: Unit Exposure, Amount of FormulationUsedIndoor Treatment - 1 Post Inhalation Inhalation 103: Air Concentration, SpecifiedCustom - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPCustom - 1 Post Inhalation Inhalation 104: Air Concentration, CalculatedScenarios & ProductsScenarioProductCASProduct ProbabilityOutdoor Fogger Use P101;Outdoor TotalRelease FoggerTetramethrin 1Indoor Treatment P102;Indoor Spray -Aerosol CanTetramethrin 1Pet Care P103;Pets - AerosolCanTetramethrin 1Indoor Fogger Use P104;Indoor TotalRelease FoggerTetramethrin 1Indoor Treatment P105;Indoor Spray -RTUTetramethrin 0Custom P106;Outdoor Spray -Handheld FoggerTetramethrin 0.5Custom P107;Outdoor Spray -Aerosol CanTetramethrin 0.5Scenario ProbabilitiesPage 14 of 25ScenarioScenarioProbabilityMarket Share (ChemicalProbability)Pet Care - 1 0 0Outdoor Fogger Use - 1 0 0Indoor Fogger Use - 1 0 0Indoor Treatment - 1 1 1Custom - 1 0 0Event AllocationMonthly Probabilities (Jan-Jun)ScenarioJanFebMarAprMayJunPet Care - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Outdoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Indoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Indoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Custom - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Monthly Probabilities (Jul-Dec)ScenarioJulAugSepOctNovDecPet Care - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Outdoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Indoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Indoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Custom - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Day of Week ProbabilitiesScenarioSunMonTueWedThrFriSatPet Care - 1 0.1429 0.14290.1429 0.1429 0.1429 0.1429 0.1429Outdoor Fogger Use - 1 0.14290.1429 0.1429 0.1429 0.1429 0.1429 0.1429Indoor Fogger Use - 1 0.14290.1429 0.1429 0.1429 0.1429 0.1429 0.1429Indoor Treatment - 1 0.14290.1429 0.1429 0.1429 0.1429 0.1429 0.1429Custom - 1 0.1429 0.14290.1429 0.1429 0.1429 0.1429 0.1429Annual Use & Treatment IntervalScenario# UsesTreatment Interval (Days)Pet Care - 1 Single (10) Single (10)Outdoor Fogger Use - 1 Single (10) Single (10)Indoor Fogger Use - 1 Single (10) Single (10)Indoor Treatment - 1 Single (10) Single (10)Custom - 1 Single (10) Single (10)Page 15 of 25Co-OccurrenceScenario 1Scenario 2Co-OccurencePet Care - 1 Pet Care - 1 0Pet Care - 1 Outdoor Fogger Use - 1 0Pet Care - 1 Indoor Fogger Use - 1 0Pet Care - 1 Indoor Treatment - 1 0Pet Care - 1 Custom - 1 0Outdoor Fogger Use - 1 Pet Care - 1 0Outdoor Fogger Use - 1 Outdoor Fogger Use - 1 0Outdoor Fogger Use - 1 Indoor Fogger Use - 1 0Outdoor Fogger Use - 1 Indoor Treatment - 1 0Outdoor Fogger Use - 1 Custom - 1 0Indoor Fogger Use - 1 Pet Care - 1 0Indoor Fogger Use - 1 Outdoor Fogger Use - 1 0Indoor Fogger Use - 1 Indoor Fogger Use - 1 0Indoor Fogger Use - 1 Indoor Treatment - 1 0Indoor Fogger Use - 1 Custom - 1 0Indoor Treatment - 1 Pet Care - 1 0Indoor Treatment - 1 Outdoor Fogger Use - 1 0Indoor Treatment - 1 Indoor Fogger Use - 1 0Indoor Treatment - 1 Indoor Treatment - 1 0Indoor Treatment - 1 Custom - 1 0Custom - 1 Pet Care - 1 0Custom - 1 Outdoor Fogger Use - 1 0Custom - 1 Indoor Fogger Use - 1 0Custom - 1 Indoor Treatment - 1 0Custom - 1 Custom - 1 0INPUTSScenario-SpecificGroupVariable NameUnitValueOutdoor Fogger Use - 1 Exposure Duration (Adult) hr/day Uniform (1,2)Outdoor Fogger Use - 1 Exposure Duration (Child) hr/day Percentile2 (interpolated)(0 0 5 0.083 25 0.75 50 0.975 2.4 90 3.5 100 3.5)Indoor Treatment - 1 Exposure Duration (Adult) hr/day Uniform (1,8)Indoor Treatment - 1 Exposure Duration (Child) hr/day Uniform (1,8)Custom - 1 Exposure Duration (Adult) hr/day Uniform (1,2)Custom - 1 Exposure Duration (Child)hr/day Percentile2 (interpolated)Page 16 of 25(0 0 5 0.083 25 0.75 50 0.975 2.4 90 3.5 100 3.5)Method-SpecificGroupVariable NameUnitValuePet Care - 1 ; Ingestion 109: EPA SOP ContactFrequency (Hand-to-Mouth) event/hr Triangular(1,13,26)Pet Care - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth)unitless Uniform(0.2,0.5)Pet Care - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Triangular(0.03,0.108,1.03)Pet Care - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular(1,7,20)Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular(1,6,26)Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOPTransfer Efficiency per Contact (Hand-toMouth)unitless Uniform(0.2,0.5)Outdoor Fogger Use - 1 ; Ingestion 109: EPASOP Exposure Duration hr/day Uniform (1,2)Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular(1,7,20)Outdoor Fogger Use - 1 ; Inhalation 104: Air Concentration,CalculatedDilution Factor (Indoor or Outdoor Air) unitless Single (0.01)Outdoor Fogger Use - 1 ; Inhalation 104: Air Concentration,CalculatedVolume (Indoor or Outdoor) m3 Single (130.2)Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP ContactFrequency (Hand-to-Mouth) event/hr Triangular(1,13,26)Indoor Fogger Use - 1 ; Ingestion 109: EPA SOPTransfer Efficiency per Contact (Hand-toMouth)unitless Uniform(0.2,0.5)Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,5)Indoor Fogger Use - 1 ; Ingestion 109: EPA SOPSurface Area - Hands (Mouthed) cm2 Triangular(1,7,20)Indoor Treatment - 1 ; Ingestion 109: EPA SOP ContactFrequency (Hand-to-Mouth) event/hr Triangular(1,13,26)Indoor Treatment - 1 ; Ingestion 109: EPA SOPTransfer Efficiency per Contact (Hand-toMouth)unitlessUniform(0.1,0.5)Indoor Treatment - 1 ; Ingestion 109: EPA SOPExposure Durationhr/dayUniform (1,4)Indoor Treatment - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular(1,7,20)Custom - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular(1,6,26)Custom - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth)unitless Uniform(0.2,0.5)Custom - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,2)Page 17 of 25Custom - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular(1,7,20)Custom - 1 ; Inhalation 104: Air Concentration, CalculatedDilution Factor (Indoor or Outdoor Air) unitless Single (0.01)Custom - 1 ; Inhalation 104: Air Concentration, Calculated Volume (Indoor or Outdoor) m3 Single (130.2)Product-specificGroupVariable NameUnitValueP101; Outdoor Total Release Fogger Application(AI per Area Treated) kg/m2 Single (0.0001)P101; Outdoor Total Release Fogger Fraction AIDislodgeable in Surface unitless Single (0.05)P101; Outdoor Total Release Fogger HalfLife day Single (0.00001)P101; Outdoor Total Release Fogger Amount ofFormulation Used (Volume) cm3 Single (170)P101; Outdoor Total Release Fogger FractionAI in Formulation unitless Single (0.0054)P101; Outdoor Total Release Fogger Density of Formulation g/cm3 Single (1)P102; Indoor Spray - Aerosol CanApplication (AI per Area Treated)mg/cm2Uniform(0.0085,0.017)P102; Indoor Spray - Aerosol Can Fraction AI Dislodgeable in Surface unitless LogNormal(0.032,0.018,0.01,0.19)P102; Indoor Spray - Aerosol Can HalfLife day Single (7)P102; Indoor Spray - Aerosol Can Application (Amount of AI Used) kg/m3 Single (2.5)P102; Indoor Spray - Aerosol Can Amount ofFormulation Used (Volume) m3 Single(0.000454)P102; Indoor Spray - Aerosol Can Unit Exposure (Inhalation) mg/lb Single (1.3)P102; Indoor Spray - Aerosol Can Concentration of AI in Air mg/m3 Uniform(0.00022,0.011)P103; Pets - Aerosol Can Application (AIper Area Treated) mg/cm2 Single (0.024)P103; Pets - Aerosol Can Fraction AI Dislodgeable in Surface unitless Single (0.02)P103; Pets - Aerosol Can HalfLife day Single (0.00001)P104; Indoor Total Release Fogger Application (AI per Area Treated) mg/cm2 Single (0.00129)P104; Indoor Total Release Fogger Fraction AI Dislodgeable in Surface unitless LogNormal(0.032,0.018,0.01,0.19)P104; Indoor Total Release Fogger HalfLife day Single (0.00001)P105; Indoor Spray - RTU Application (AI per Area Treated) mg/cm2 Single (0.0051)P105; Indoor Spray - RTU Fraction AI Dislodgeable in Surface unitless LogNormal(0.032,0.018,0.01,0.19)P105; Indoor Spray - RTU HalfLife day Single (0.00001)P105; Indoor Spray - RTU Application (Amount of AI Used) lb/gal Single (0.02)P105; Indoor Spray - RTU Amount of Formulation Used (Volume) gal Single (1)P105; Indoor Spray - RTU Unit Exposure (Inhalation) mg/lb Single (0.123)P105; Indoor Spray - RTU Concentration of AI in Air mg/m3 Uniform(0.00022,0.011)Page 18 of 25P106; Outdoor Spray - Handheld Fogger Application (AI per Area Treated) mg/cm2 Single(0.000053)P106; Outdoor Spray - Handheld Fogger Fraction AIDislodgeable in Surface unitless Single (0.05)P106; Outdoor Spray - Handheld Fogger HalfLife day Single (0.00001)P106; Outdoor Spray - Handheld Fogger Amount ofFormulation Used (Volume) oz Single (1)P106; Outdoor Spray - Handheld Fogger Fraction AI in Formulation unitless Single (0.001)P106; Outdoor Spray - Handheld Fogger Density of Formulation g/cm3 Single (1)P107; Outdoor Spray - Aerosol Can Application(AI per Area Treated) mg/cm2 Single (0.01)P107; Outdoor Spray - Aerosol Can Fraction AI Dislodgeable in Surface unitless Single (0.05)P107; Outdoor Spray - Aerosol Can HalfLife day Single (0.00001)P107; Outdoor Spray - Aerosol Can Amount ofFormulation Used (Volume) cm3 Single (170)P107; Outdoor Spray - Aerosol Can FractionAI in Formulation unitless Single (0.0054)P107; Outdoor Spray - Aerosol Can Density of Formulation g/cm3 Single (1)Page 19 of 25APPENDIX BINPUTS FOR “PROBABILISTIC C”Residential Wizard SettingsName: Valent TetramethrinAuthor: Muhilan PandianDate: Thursday, March 20, 2008Comments: Tetramethrin CARESAssessment - March/April 2008Scenarios & MethodsScenarioDuring/PostRouteMethodPet Care - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPOutdoor Fogger Use - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPOutdoor Fogger Use - 1 Post Inhalation Inhalation 104: Air Concentration, CalculatedIndoor Fogger Use - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPIndoor Treatment - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPIndoor Treatment - 1 During Inhalation Inhalation 102: Unit Exposure, Amount of FormulationUsedIndoor Treatment - 1 Post Inhalation Inhalation 103: Air Concentration, SpecifiedCustom - 1 Post Ingestion (H-To-M) Ingestion 109: EPA SOPCustom - 1 Post Inhalation Inhalation 104: Air Concentration, CalculatedScenarios & ProductsScenarioProductCASProduct ProbabilityOutdoor Fogger Use P101;Outdoor TotalRelease FoggerTetramethrin 1Indoor Treatment P102;Indoor Spray -Aerosol CanTetramethrin 1Pet Care P103;Pets - AerosolCanTetramethrin 1Indoor Fogger Use P104;Indoor TotalRelease FoggerTetramethrin 1Indoor Treatment P105;Indoor Spray -RTUTetramethrin 0Custom P106;Outdoor Spray -Handheld FoggerTetramethrin 0.5Custom P107;Outdoor Spray -Aerosol CanTetramethrin 0.5Scenario ProbabilitiesScenarioScenarioMarket Share (ChemicalPage 20 of 25ProbabilityProbability)Pet Care - 1 0 0Outdoor Fogger Use - 1 0 0Indoor Fogger Use - 1 0 0Indoor Treatment - 1 1 1Custom - 1 0 0Event AllocationMonthly Probabilities (Jan-Jun)ScenarioJanFebMarAprMayJunPet Care - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Outdoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Indoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Indoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Custom - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Monthly Probabilities (Jul-Dec)ScenarioJulAugSepOctNovDecPet Care - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Outdoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Indoor Fogger Use - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Indoor Treatment - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Custom - 1 0.0833 0.0833 0.0833 0.0833 0.0833 0.0833Day of Week ProbabilitiesScenarioSunMonTueWedThrFriSatPet Care - 1 0.1429 0.14290.1429 0.1429 0.1429 0.1429 0.1429Outdoor Fogger Use - 1 0.14290.1429 0.1429 0.1429 0.1429 0.1429 0.1429Indoor Fogger Use - 1 0.14290.1429 0.1429 0.1429 0.1429 0.1429 0.1429Indoor Treatment - 1 0.14290.1429 0.1429 0.1429 0.1429 0.1429 0.1429Custom - 1 0.1429 0.14290.1429 0.1429 0.1429 0.1429 0.1429Annual Use & Treatment IntervalScenario# UsesTreatment Interval (Days)Pet Care - 1 Single (10) Single (10)Outdoor Fogger Use - 1 Single (10) Single (10)Indoor Fogger Use - 1 Single (10) Single (10)Indoor Treatment - 1 Single (10) Single (10)Custom - 1 Single (10) Single (10)Page 21 of 25Co-OccurrenceScenario 1Scenario 2Co-OccurencePet Care - 1 Pet Care - 1 0Pet Care - 1 Outdoor Fogger Use - 1 0Pet Care - 1 Indoor Fogger Use - 1 0Pet Care - 1 Indoor Treatment - 1 0Pet Care - 1 Custom - 1 0Outdoor Fogger Use - 1 Pet Care - 1 0Outdoor Fogger Use - 1 Outdoor Fogger Use - 1 0Outdoor Fogger Use - 1 Indoor Fogger Use - 1 0Outdoor Fogger Use - 1 Indoor Treatment - 1 0Outdoor Fogger Use - 1 Custom - 1 0Indoor Fogger Use - 1 Pet Care - 1 0Indoor Fogger Use - 1 Outdoor Fogger Use - 1 0Indoor Fogger Use - 1 Indoor Fogger Use - 1 0Indoor Fogger Use - 1 Indoor Treatment - 1 0Indoor Fogger Use - 1 Custom - 1 0Indoor Treatment - 1 Pet Care - 1 0Indoor Treatment - 1 Outdoor Fogger Use - 1 0Indoor Treatment - 1 Indoor Fogger Use - 1 0Indoor Treatment - 1 Indoor Treatment - 1 0Indoor Treatment - 1 Custom - 1 0Custom - 1 Pet Care - 1 0Custom - 1 Outdoor Fogger Use - 1 0Custom - 1 Indoor Fogger Use - 1 0Custom - 1 Indoor Treatment - 1 0Custom - 1 Custom - 1 0INPUTSScenario-SpecificGroupVariable NameUnitValueOutdoor Fogger Use - 1 Exposure Duration (Adult) hr/day Uniform (1,2)Outdoor Fogger Use - 1 Exposure Duration (Child) hr/day Percentile2 (interpolated)(0 0 5 0.083 25 0.75 50 0.975 2.4 90 3.5 100 3.5)Indoor Treatment - 1 Exposure Duration (Adult) hr/day Uniform (1,8)Indoor Treatment - 1 Exposure Duration (Child) hr/day Uniform (1,8)Custom - 1 Exposure Duration (Adult) hr/day Uniform (1,2)Custom - 1 Exposure Duration (Child)hr/day Percentile2 (interpolated)(0 0 5 0.083 25 0.75 50 0.9Page 22 of 2575 2.4 90 3.5 100 3.5)Method-SpecificGroupVariable NameUnitValuePet Care - 1 ; Ingestion 109: EPA SOP ContactFrequency (Hand-to-Mouth) event/hr Triangular(1,13,26)Pet Care - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth)unitless Uniform(0.2,0.5)Pet Care - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Triangular(0.03,0.108,1.03)Pet Care - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular(1,7,20)Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular(1,6,26)Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOPTransfer Efficiency per Contact (Hand-toMouth)unitless Uniform(0.2,0.5)Outdoor Fogger Use - 1 ; Ingestion 109: EPASOP Exposure Duration hr/day Uniform (1,2)Outdoor Fogger Use - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular(1,7,20)Outdoor Fogger Use - 1 ; Inhalation 104: Air Concentration,CalculatedDilution Factor (Indoor or Outdoor Air) unitless Single (0.01)Outdoor Fogger Use - 1 ; Inhalation 104: Air Concentration,CalculatedVolume (Indoor or Outdoor) m3 Single (130.2)Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP ContactFrequency (Hand-to-Mouth) event/hr Triangular(1,13,26)Indoor Fogger Use - 1 ; Ingestion 109: EPA SOPTransfer Efficiency per Contact (Hand-toMouth)unitless Uniform(0.2,0.5)Indoor Fogger Use - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,5)Indoor Fogger Use - 1 ; Ingestion 109: EPA SOPSurface Area - Hands (Mouthed) cm2 Triangular(1,7,20)Indoor Treatment - 1 ; Ingestion 109: EPA SOP ContactFrequency (Hand-to-Mouth) event/hr Triangular(1,13,26)Indoor Treatment - 1 ; Ingestion 109: EPA SOPTransfer Efficiency per Contact (Hand-toMouth)unitlessUniform(0.2,0.5)Indoor Treatment - 1 ; Ingestion 109: EPA SOPExposure Durationhr/dayUniform (1,5)Indoor Treatment - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 Triangular(1,7,20)Custom - 1 ; Ingestion 109: EPA SOP Contact Frequency (Hand-to-Mouth) event/hr Triangular(1,6,26)Custom - 1 ; Ingestion 109: EPA SOP Transfer Efficiency per Contact (Hand-toMouth)unitless Uniform(0.2,0.5)Custom - 1 ; Ingestion 109: EPA SOP Exposure Duration hr/day Uniform (1,2)Custom - 1 ; Ingestion 109: EPA SOP Surface Area - Hands (Mouthed) cm2 TriangularPage 23 of 25(1,7,20)Custom - 1 ; Inhalation 104: Air Concentration, CalculatedDilution Factor (Indoor or Outdoor Air) unitless Single (0.01)Custom - 1 ; Inhalation 104: Air Concentration, Calculated Volume (Indoor or Outdoor) m3 Single (130.2)Product-specificGroupVariable NameUnitValueP101; Outdoor Total Release Fogger Application(AI per Area Treated) kg/m2 Single (0.0001)P101; Outdoor Total Release Fogger Fraction AIDislodgeable in Surface unitless Single (0.05)P101; Outdoor Total Release Fogger HalfLife day Single (0.00001)P101; Outdoor Total Release Fogger Amount ofFormulation Used (Volume) cm3 Single (170)P101; Outdoor Total Release Fogger FractionAI in Formulation unitless Single (0.0054)P101; Outdoor Total Release Fogger Density of Formulation g/cm3 Single (1)P102; Indoor Spray - Aerosol CanApplication (AI per Area Treated)mg/cm2Uniform(0.0085,0.017)P102; Indoor Spray - Aerosol Can Fraction AI Dislodgeable in Surface unitless LogNormal(0.032,0.018,0.01,0.19)P102; Indoor Spray - Aerosol Can HalfLife day Single (7)P102; Indoor Spray - Aerosol Can Application (Amount of AI Used) kg/m3 Single (2.5)P102; Indoor Spray - Aerosol Can Amount ofFormulation Used (Volume) m3 Single(0.000454)P102; Indoor Spray - Aerosol Can Unit Exposure (Inhalation) mg/lb Single (1.3)P102; Indoor Spray - Aerosol Can Concentration of AI in Air mg/m3 Uniform(0.00022,0.011)P103; Pets - Aerosol Can Application (AIper Area Treated) mg/cm2 Single (0.024)P103; Pets - Aerosol Can Fraction AI Dislodgeable in Surface unitless Single (0.02)P103; Pets - Aerosol Can HalfLife day Single (0.00001)P104; Indoor Total Release Fogger Application (AI per Area Treated) mg/cm2 Single (0.00129)P104; Indoor Total Release Fogger Fraction AI Dislodgeable in Surface unitless LogNormal(0.032,0.018,0.01,0.19)P104; Indoor Total Release Fogger HalfLife day Single (0.00001)P105; Indoor Spray - RTU Application (AI per Area Treated) mg/cm2 Single (0.0051)P105; Indoor Spray - RTU Fraction AI Dislodgeable in Surface unitless LogNormal(0.032,0.018,0.01,0.19)P105; Indoor Spray - RTU HalfLife day Single (0.00001)P105; Indoor Spray - RTU Application (Amount of AI Used) lb/gal Single (0.02)P105; Indoor Spray - RTU Amount of Formulation Used (Volume) gal Single (1)P105; Indoor Spray - RTU Unit Exposure (Inhalation) mg/lb Single (0.123)P105; Indoor Spray - RTU Concentration of AI in Air mg/m3 Uniform(0.00022,0.011)P106; Outdoor Spray - Handheld Fogger Application (AI per Area Treated) mg/cm2 SinglePage 24 of 25(0.000053)P106; Outdoor Spray - Handheld Fogger Fraction AIDislodgeable in Surface unitless Single (0.05)P106; Outdoor Spray - Handheld Fogger HalfLife day Single (0.00001)P106; Outdoor Spray - Handheld Fogger Amount ofFormulation Used (Volume) oz Single (1)P106; Outdoor Spray - Handheld Fogger Fraction AI in Formulation unitless Single (0.001)P106; Outdoor Spray - Handheld Fogger Density of Formulation g/cm3 Single (1)P107; Outdoor Spray - Aerosol Can Application(AI per Area Treated) mg/cm2 Single (0.01)P107; Outdoor Spray - Aerosol Can Fraction AI Dislodgeable in Surface unitless Single (0.05)P107; Outdoor Spray - Aerosol Can HalfLife day Single (0.00001)P107; Outdoor Spray - Aerosol Can Amount ofFormulation Used (Volume) cm3 Single (170)P107; Outdoor Spray - Aerosol Can FractionAI in Formulation unitless Single (0.0054)P107; Outdoor Spray - Aerosol Can Density of Formulation g/cm3 Single (1)

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# Attachment 1

Tetramethrin CARES Submission MRID 47713101