Initial to indicate certification as to information on this page

(full text of certification is on page one).

Date

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. 

Use additional sheet(s) if necessary.

2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product 

Registration

5. I wish to cancel 

this product 

registration 

voluntarily

6. Generic Data 7. Product Specific Data

6a. I am claiming a Generic Data 

Exemption because I obtain the 

active ingredient from the source 

EPA registration number listed 

below.

6b. I agree to satisfy Generic Data

Requirements as indicated on the 

attached form entitled 

"Requirements Status and 

Registrant's Response."

7a. My product is an MUP and I 

agree to satisfy the MUP 

requirement on the attached form

entitled "Requirements Status and

Registrant's Response."

7b. My product is an EUP and I 

agree to satisfy the EUP 

requirement on the attached form 

entitled "Requirements Status and 

Registrant's Response."

OMB Approval 2070-0174

1. Company Name and Address

 

0382 - Ethephon

Chemical # and Name: 099801

Ethephon

10-Jan-2012

GENERIC

ID # GDCI-099801-1066

United States Environmental Protection Agency

Washington, D.C. 20460

DATA CALL-IN RESPONSE

Page of 1 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

Signature and Title of Company's Authorized Representative ______________________________________________________

10. Name of Company

N/A N/A

9. Date

11. Phone Number 
Initial to indicate certification as to information on this page (full text of certification is on page one) 

13. Phone Number

10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any 

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

12. Name of Company

11. Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

 

Environmental Fate Data Requirements (Conventional 

Chemical)

Nontarget Plant Protection Data Requirements (Conventional 

Chemical)

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

835.4100

835.4300

835.6100

835.6200

850.4100

850.4150

850.1075

Aerobic soil metabolism

Aerobic aquatic metabolism

Terrestrial field dissipation

Aquatic field dissipation

Terrestrial Plant Toxicity (Seedling Emergence)

Terrestrial plant toxicity, Tier 1 (vegetative vigor)

Fish acute toxicity test, freshwater and marine

0382 - Ethephon

Chemical # and Name: 099801

Ethephon

10-Jan-2012

GENERIC

ID # GDCI-099801-1066

A,B,C,I,Q

A,B,C,I,Q

A,B,C,I,Q

A,B,C,I,Q

A,B,C,I,Q

A,B,C,I,Q

A,B,C,I,Q

PAIRA; TGAI

PAIRA; TGAI

TEP

TEP

TEP

TEP

TEP; TGAI

24

24

24

24

12

12

12

Page 1 of 

(5)

(4)

(3, 7, 9)

(2, 7, 9)

N

N

N

N

N

N

N

2
Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

 

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

Toxicology Data Requirements (Conventional Chemical)

850.1400

850.2100

850.2300

850.3020

870.3465

870.7800

SS-1037

Fish early-life stage toxicity test

Avian acute oral toxicity test

Avian reproduction test

Honey bee acute contact toxicity

90-day inhalation toxicity

Immunotoxicity

Greenhouse Foliar Degradation Study

0382 - Ethephon

Chemical # and Name: 099801

Ethephon

10-Jan-2012

GENERIC

ID # GDCI-099801-1066

A,B,C,I,Q

A,B,C,I,Q

A,B,C,I,Q

A,B,C,I,Q

A,B,C,I,Q

A,B,C,I,Q

A,B,C,I,Q

TGAI

TEP; TGAI

TGAI

TGAI

TGAI

TGAI

EP; PAI; TGAI

12

12

24

12

24

12

24

Page 2 of 

(1, 6)

(1, 8)

N

Y

N

N

N

N

Y

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

0382 - Ethephon

GDCI-099801-1066

1

2

3

4

5

6

7

8

9

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

The proposed protocol is to be submitted to the Agency within 90 days of receipt of this DCI for review and approval prior to study inception.

Refer to public draft guideline 850.4250 for guidance on Tier II vegetative vigor testing.

Refer to public draft guideline 850.4225 for guidance on Tier II seedling emergence testing.

EPA requires only the environmental chemistry analytical method portion of GDLN 835.6200 (aquatic sediment field dissipation).

EPA requires only the environmental chemistry analytical method portion of GDLN 835.6100 (terrestrial field dissipation)

EPA requires data from a study using a Passerine species, selected by the registrant in consultation with the Agency.

Data are required for six species of dicots from at least four families, one species of which is soybean (Glycine max). Data are required for four species of monocots from at least two families,

one species which is corn (Zea mays). At least one of either the monocot or dicot species must be a root crop.

A foliar dissipation study of ethephon applied to cotton in a greenhouse is required, including measurement of ethylene being released from foliar residues of ethephon.

A Tier II study is required. A Tier I plant study may be conducted in lieu of a Tier II study with the understanding that any adverse effects observed by the Tier I study would necessitate conduct

and submission of a Tier II study as well. The purpose of a Tier II study is to establish both a definitive No Observed Adverse Effect Concentration (NOAEC), or alternatively, a concentration at 

which there is a 5% observed inhibition effect (IC05), to be used in a risk assessment and effects determination for endangered or threatened species (listed species), and a definitive IC25 

(concentration at which there is a 25% observed inhibition effect) for assessing risk to non-listed nontarget plants. If any adverse effects are observed in a Tier I study and neither a definitive 

NOAEC nor a definitive IC05 value is available, then the Agency may have to presume in its effects determination, that Ethephon "may affect" and is "likely to adversely affect" listed plant 

species.

Case # and Name:

DCI Number:

Page: 1 of 1

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. 

These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement.

Use Categories Key:

A - Terrestrial food crop

B - Terrestrial feed crop

C - Terrestrial nonfood crop

I - Greenhouse nonfood crop

Q - Residential outdoor use
United States Environmental Protection Agency 

Washington, D.C. 20460

LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE

Case # and Name: 0382 - Ethephon

Page: 1 of 1

83558 CELSIUS PROPERTY B.V., AMSTERDAM 

(NL) 

Co. Nr. Company Name Agent For Company

MAKHTESHIM AGAN OF NORTH 

AMERICA, INC.

3120 HIGHWOODS BLVD., SUITE 100

Address City ZIP

RALEIGH 27604 

OMB Approval 2070-0174

State

NC

 DCI Number: GDCI-099801-1066
LINKS TO FORMS:

The pesticide registration forms that are listed below can be found at:

http://www.epa.gov/opprd001/forms/

Link to Confidential Statement of Formula and Instructions (Form # 8570-4)

http://www.epa.gov/opprd001/forms/8570-4.pdf

Certification of Attempt to Enter Into an Agreement With Registrants for 

Development of Data (Form # 8570-32)

http://www.epa.gov/opprd001/forms/8570-32.pdf

Certification With Respect to Citation of Data (Form # 8570-34)

http://www.epa.gov/opprd001/forms/8570-34.pdf