EXHIBIT 12.2
COMPUTATION IN SUPPORT OF RATIO OF EARNINGS TO FIXED CHARGES
AMERICAN EXPRESS COMPANY

|                                         |  |                          |       |      |   |       |  |      |       |      |   |        |  |   |      
|---------------------------------------- |  | ------------------------ | ----- | ---- | - | ----- |  | ---- | ----- | ---- | - | ------ |  | - | -----
|                                         |  |                         
|                                         |  | Years Ended December 31,
|                                         |  |                         
|(Dollars in
 Millions)                   |  | 2010                     |       | 2009 |   | 2008  |  | 2007 |       | 2006
|                                         |  |                          |       |      |   |       |  |      |       |     
|Earnings:                                |  |                          |       |      |   |       |  |      |       |      |   |        |  |   |      
|Pretax income from continuing operations |  | $                        | 5,964 |      | $ | 2,841 |  | $    | 3,581 |      | $ | 5,694  |  | $ | 5,152
|Interest expense                         |  |                          | 2,423 |      |   | 2,208 |  |      | 3,628 |      |   | 4,525  |  |   | 3,258
|Other adjustments                        |  |                          | 126   |      |   | 129   |  |      | 144   |      |   | 143    |  |   | 139  
|                                         |  |                          |       |      |   |       |  |      |       |      |   |        |  |   |      
|Total earnings (a)                       |  | $                        | 8,513 |      | $ | 5,178 |  | $    | 7,353 |      | $ | 10,362 |  | $ | 8,549
|                                         |  |                          |       |      |   |       |  |      |       |      |   |        |  |   |      
|                                         |  |                          |       |      |   |       |  |      |       |      |   |        |  |   |      
|Fixed charges:                           |  |                          |       |      |   |       |  |      |       |      |   |        |  |   |      
|Interest expense                         |  | $                        | 2,423 |      | $ | 2,208 |  | $    | 3,628 |      | $ | 4,525  |  | $ | 3,258
|Other adjustments                        |  |                          | 85    |      |   | 121   |  |      | 114   |      |   | 106    |  |   | 106  
|                                         |  |                          |       |      |   |       |  |      |       |      |   |        |  |   |      
|Total fixed charges (b)                  |  | $                        | 2,508 |      | $ | 2,329 |  | $    | 3,742 |      | $ | 4,631  |  | $ | 3,364
|                                         |  |                          |       |      |   |       |  |      |       |      |   |        |  |   |      
|                                         |  |                          |       |      |   |       |  |      |       |      |   |        |  |   |      
|Ratio of earnings to fixed charges (a/b) |  |                          | 3.39  |      |   | 2.22  |  |      | 1.96  |      |   | 2.24   |  |   | 2.54 
|                                         |  |                          |       |      |   |       |  |      |       |      |   |        |  |   |      

Included in interest expense in the above computation is interest
expense related to the cardmember lending activities, international banking
operations, and charge card and other activities in the Consolidated Statements
of Income. Interest expense does not include interest on liabilities recorded
under GAAP governing accounting for uncertainty in income taxes as American
Express policy is to classify such interest in income tax provision in the
Consolidated Statements of Income.

For purposes of the earnings computation, other adjustments include
adding the amortization of capitalized interest, the net loss of affiliates
accounted for under the equity method whose debt is not guaranteed by American
Express, the noncontrolling interest in the earnings of majority-owned
subsidiaries with fixed charges, and the interest component of rental expense
and subtracting undistributed net income of affiliates accounted for under the
equity method.

For purposes of the fixed charges computation, other adjustments
include capitalized interest costs and the interest component of rental
expense.

E-6

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