### 76460 Federal Register / Vol. 75, No. 235 / Wednesday, December 8, 2010 / Notices

approach may allow estimation of dataderived uncertainty factors that consider use of toxicokinetic and toxicodynamic data to inform quantitative extrapolations for interspecies differences and human variability in dose response assessment. The topics to be covered in the February 2011 SAP are consistent with EPA’s Office of Pesticide Programs continuing efforts to improve the scientific basis for risk assessment by broadening the application of probabilistic exposure techniques and PBPK models. The Agency has a conceptually similar effort on-going to link PBPK models for pyrethroids with Stochastic Human Exposure and Dose Simulator (SHEDS) exposure software, a probabilistic exposure model developed by the EPA’s Office of Research and Development, which was reviewed by the SAP in July 2010. The current effort by Dow AgroSciences is a research effort which may, if sufficiently robust, inform future risk assessments; the February meeting is a key milestone in this research. The Agency will solicit feedback from the Panel on technical issues related to PBPK/PD model, the proposed approach for merging the PBPK/PD model with CARES, and the use of such merged models in risk assessment.
C. FIFRA SAP Documents and Meeting Minutes

EPA’s background paper, related supporting materials, charge/questions to FIFRA SAP, FIFRA SAP composition ( i.e., members and ad hoc members for this meeting), and the meeting agenda will be available by late January 2011. In addition, the Agency may provide additional background documents as the materials become available. You may obtain electronic copies of these documents, and certain other related documents that might be available electronically, at http:// www.regulations.gov and the FIFRA SAP homepage at http://www.epa.gov/ scipoly/sap.

FIFRA SAP will prepare meeting minutes summarizing its recommendations to the Agency approximately 90 days after the meeting. The meeting minutes will be posted on the FIFRA SAP Web site or may be obtained from the OPP Regulatory Public Docket at http:// www.regulations.gov.
List of Subjects

Environmental protection, Pesticides and pests. Dated: November 23, 2010. Frank Sanders, Director, Office of Science Coordination and Policy.
[FR Doc. 2010–30630 Filed 12–7–10; 8:45 am]

**BILLING CODE 6560–50–P**

**ENVIRONMENTAL PROTECTION AGENCY** 

**[FRL–9236–6; Docket ID No. EPA–HQ–ORD– 2010–0991]** 

**Lymphohematopoietic Cancers Induced by Chemicals and Other**  **Agents: Overview and Implications for Risk Assessment** 

**AGENCY :**  Environmental Protection Agency (EPA).

**ACTION :**  Notice of public comment period.

**SUMMARY :**  EPA is announcing a 45-day public comment period for the draft document titled,

‘‘ Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview and Implications for Risk Assessment’’ (EPA/600/R–10/ 095A). The draft document was prepared by the National Center for Environmental Assessment within EPA’s Office of Research and Development. The draft document provides an overview of the types and mechanisms underlying the lymphohematopoietic cancers induced by chemical agents and radiation in humans, with a primary emphasis on leukemia and leukemia-inducing agents. In addition, the document also focuses on how mechanistic information on human leukemia-inducing agents can inform risk assessment.

EPA is releasing this draft documentsolely for the purpose of predissemination peer review under applicable information quality guidelines. This draft document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy or determination. All public comments received will be provided to the peer reviewers at the beginning of the review process.

**DATES :**  The 45-day public comment period begins December 8, 2010, and ends January 24, 2011. Technical comments should be in writing and must be received by EPA by January 24,
2011.

**ADDRESSES :**  The draft

‘‘ Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview and Implications for Risk Assessment’’ is available primarily via the Internet on the National Center for Environmental Assessment’s home page under the Recent Additions and the Data and Publications menus at http://www.epa.gov/ncea. A limited number of paper copies are available from the Information Management Team, NCEA; telephone: 703–347–8561; facsimile: 703–347–8691. If you are requesting a paper copy, please provide your name, your mailing address, and the draft document title,

‘‘ Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview and Implications for Risk Assessment. ’’

Comments may be submitted electronically via http:// www.regulations.gov, by mail, by facsimile, or by hand delivery/courier. Please follow the detailed instructions provided in the **SUPPLEMENTARY**
**INFORMATION** section of this notice.

**FOR FURTHER INFORMATION CONTACT :**  For information on the public comment period, contact the Office of Environmental Information Docket; telephone: 202–566–1752; facsimile: 202–566–1753; or e-mail: ORD.Docket@epa.gov.

For technical information, contact Nagu Keshava, NCEA; telephone: 919– 541–3047; facsimile: 919–541–0245; or e-mail: keshava.nagu@epa.gov.

**SUPPLEMENTARY INFORMATION :**  I. Information About the Project/ Document

This project was initiated to better understand the mechanisms underlying the lymphohematopoietic cancers induced by chemical agents in humans. A draft report was developed that provides an overview of types and mechanisms underlying the lymphohematopoietic cancers induced by both chemical agents and radiation in humans, with a primary emphasis on leukemia and leukemia-inducing agents.

II. How to Submit Technical Comments to the Docket at http:// www.regulations.gov

Submit your comments, identified by Docket ID No. EPA–HQ–ORD–2010– 0991, by one of the following methods:

• http://www.regulations.gov: Follow the on-line instructions for submitting
comments.

• E-mail: ORD.Docket@epa.gov.

• Fax: 202–566–1753.

• Mail: Office of Environmental Information (OEI) Docket (Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202–566–1752.

• Hand Delivery: The OEI Docket is located in the EPA Headquarters Docket


### 76461 Federal Register / Vol. 75, No. 235 / Wednesday, December 8, 2010 / Notices

Center, Room 3334 EPA West Building, 1301 Constitution Ave., NW., Washington, DC. The EPA Docket Center Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number for the Public Reading Room is 202–566–1744. Such deliveries are only accepted during the docket’s normal hours of operation, and special arrangements should be made for deliveries of boxed information. If you provide comments by mail or hand delivery, please submit three copies of the comments. For attachments, provide an index, number pages consecutively with the comments, and submit an unbound original and three copies.

Instructions: Direct your comments to Docket ID No. EPA–HQ–ORD–2010– 0991. Please ensure that your comments are submitted within the specified comment period. Comments received after the closing date will be marked

‘‘ late, ’’ and may only be considered if time permits. It is EPA’s policy to include all comments it receives in the public docket without change and to make the comments available online at http://www.regulations.gov, including any personal information provided, unless a comment includes information claimed to be Confidential Business Information (CBI) or other information whose disclosure is restricted by statute. Do not submit information that you consider to be CBI or otherwise protected through http:// www.regulations.gov or e-mail. The http://www.regulations.gov Web site is

an ‘‘ anonymous access ’’ system, which means EPA will not know your identity or contact information unless you provide it in the body of your comment. If you send an e-mail comment directly to EPA without going through http:// www.regulations.gov, your e-mail address will be automatically captured and included as part of the comment that is placed in the public docket and made available on the Internet. If you submit an electronic comment, EPA recommends that you include your name and other contact information in the body of your comment and with any disk or CD–ROM you submit. If EPA cannot read your comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic files should avoid the use of special characters, any form of encryption, and be free of any defects or viruses. For additional information about EPA’s public docket visit the EPA Docket Center homepage at http:// www.epa.gov/epahome/dockets.htm. Docket: Documents in the docket are listed in the http://www.regulations.gov index. Although listed in the index, some information is not publicly available, e.g., CBI or other information whose disclosure is restricted by statute. Certain other materials, such as copyrighted material, are publicly available only in hard copy. Publicly available docket materials are available either electronically in http:// www.regulations.gov or in hard copy at the OEI Docket in the EPA Headquarters Docket Center.

Dated: December 2, 2010. Darrell A. Winner, Acting Director, National Center for Environmental Assessment.
[FR Doc. 2010–30848 Filed 12–7–10; 8:45 am]

**BILLING CODE 6560–50–P**

**ENVIRONMENTAL PROTECTION AGENCY** 

**[EPA–HQ–OPP–2010–0548; FRL–8852–8]**

**Petition for a Ban on Triclosan; Notice of Availability** 

**AGENCY :**  Environmental Protection Agency (EPA).

**ACTION :**  Notice.

**SUMMARY :**  This notice makes available for review and public comment a petition submitted by Beyond Pesticides, and Food & Water Watch (hereafter referred to as ‘‘the petitioners ’’ ) to the Environmental Protection Agency (hereafter referred to

as ‘‘EPA’’ or ‘‘the Agency’’ ), asking EPA to use its authority under various statutes to regulate triclosan. Triclosan is an antimicrobial substance used in pesticide products, hand sanitizers, toothpaste, and other consumer products. The petitioners claim that the

‘‘pervasive and widespread use ’’ of triclosan poses significant risks to human health and the environment. In addition, the petitioners claim that the agency failed to address the impacts posed by triclosan’s degradation products on human health and the environment, failed to conduct separate assessments for triclosan residues in contaminated drinking water and food, and is complacent in seriously addressing concerns related to antibacterial resistance and endocrine disruption. EPA has established a public docket, which contains a copy of the petition and will contain all comments received in response to this notice. The docket may be accessed as described in this notice.

**DATES :**  Comments must be received on or before February 7, 2011. **ADDRESSES :**  Submit your comments, identified by docket identification (ID) number EPA–HQ–OPP–2010–0548, by one of the following methods:

• Federal eRulemaking Portal: http:// www.regulations.gov. Follow the on-line instructions for submitting comments.

• Mail: Office of Pesticide Programs (OPP) Regulatory Public Docket (7502P), Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460–0001.

• Delivery: OPP Regulatory Public Docket (7502P), Environmental Protection Agency, Rm. S–4400, One Potomac Yard (South Bldg.), 2777 S. Crystal Dr., Arlington, VA. Deliveries are only accepted during the Docket Facility’s normal hours of operation (8:30 a.m. to 4 p.m., Monday through Friday, excluding legal holidays). Special arrangements should be made for deliveries of boxed information. The Docket Facility telephone number is (703) 305–5805.

Instructions: Direct your comments to docket ID number EPA–HQ–OPP–2010– 0548. When commenting, please specify the statute to which your comments refer (FIFRA, FFDCA, SDWA, CWA, or ESA) and the specific issue(s) raised in the petition regarding that statute on which you are commenting. EPA’s policy is that all comments received will be included in the docket withoutchange and may be made available online at http://www.regulations.gov, including any personal information provided, unless the comment includes information claimed to be Confidential Business Information (CBI) or other information whose disclosure is restricted by statute. Do not submit information that you consider to be CBI or otherwise protected through regulations.gov or e-mail. The regulations.gov Web site is an

‘‘ anonymous access ’’ system, which means EPA will not know your identity or contact information unless you provide it in the body of your comment. If you send an e-mail comment directly to EPA without going through regulations.gov, your e-mail address will be automatically captured and included as part of the comment that is placed in the docket and made available on the Internet. If you submit an electronic comment, EPA recommends that you include your name and other contact information in the body of your comment and with any disk or CD–ROM you submit. If EPA cannot read your comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic files should avoid the use of special characters, any form