UNITED STATES ENVIRONMENTAL PROTECTION AGE.NCY 

WASHINGTON, D.C 20.:00 

AUG 1 7 2£:6 

,\U:MORANDUM 

OFf1C£ OF CH£L1 1CAL SAf,r'f' 

A"IO J'OllUllON l'REVC <Jnoti 

SUOJECT: BE.-\D Chemic.al Prolil< {llCI•) for Rcgis1rn:tion C\\~ 1\crolcin (00070 1) 

FROM: 

Tllltl:: 

t'arl t·h~n. olo~is t 

Uiologic;1I t\nnlyl\i' l\rnnch 

01.·n:k Ut'f'\\'lllJ. l!cono1nist 

Econ1Jrnic \n 31 i~ llrnnch 

lliologicnl and co on1ic t\naly!"is Di\'ision (750JI') 

1\mct Jones.. Chief ~ 

Biolosical \nal~ :-.i..; rJnin · 

Diann Sirns. Ch f (, J~~ r~/--' Science lnform:uion and \nal~ s Branch 

,,., ·J L,,,, ~ 11 /{1( ltf 

Timothy Kiely. Chief n )0 U.,I/.) ~ Leu uu f •• timO '7 

Economic \n:i.l~ s llmnch 

lliological and IZconornii: 1\n:·1tysis 11i\•ision (75031

1) 

·r<>: Ke l~· B:illard. Chcn1h::11 Kc\'iC\\' ~:fan:igcr 

Ris.k ~1an:igcn cn 1 nnd l111plc111cntation Bran1,:h l 

1)1."Sticidc Rt:--<\':llu:llion l>l\'ision (7$081)) 

QJ)icc of l'es1icidc Prograrn.s (OPP) 

Prod1.1c1 Kt\ it\\' P'anrl d:atr: June 17. 201~ 

'fhc liiological nnd Economic \nn y~i,:; l)i\'i ~io n (BE1\0) Chc1nic:1I Prolilt: (liCI') pm\'idcs an 

O\'Cr\'iC\\' <.•fthc p:st 111::iJ1::ai;en1cn1 role and t.1u;:1n1i1 t1i\'c USl-lge inlC.nn.:uion a\•ailnblc tOr a 

pc)tticidc:. lnl"onn:11ion pr.J\'itl1.xl iu this l'J('J

1 nl:J)' be used by !<>tnkc:holJcrs (e.g .. ll'icrs and 

rcgi~ r.rnt.s). OPI-, risk and lx-nclit l'~.,c..· ~n'S . ()Pl' risk n1:i.n:igcrs. nnd lhc i;.cnc:r.11 public Jurint: 

the: R1:i;i~1ro1ion Re,·ic,,· process of ucrolc:in. 
1\crol.:in \\'35 registered in the United St:.)tcs in 1959. It is r"~s stc cd ns ;1n herbicide :i.nd rilgicide 

,,·ith lL.;c sites such as irriGation syslems. (t is also rcgistcf\.'d as :in :intin1ierobial ,,;lh use .sites 

such tL$ !'>CCt)n<lury oil rceo,·ery injection sys1en1s. Fom1ulntit>nS of it~ cu<l-usc products include 

prcssurii.cJ liquid :i.nd soluble concentr.uc/liquid ('LUIS. 201 4). :\Cf\)lcin earl be applied as a 

\\'ater trcau11cnt using injection cquipn1cnt (I.UIS. 201-1). 

Aerolcin i:< registered lbr control of aquatic ,,·ccds su'h us bnu:~r.;:..,'(( nd tloltins ,·eget:ition. 

algae. and n1icroorgnnisn1s su..:h a-. slinlc·IOn11ing fungi and bacteria (PPLS. 2015; Nl'IRS, 

201 S ). llS end.use product. agnJe c 1-1 Herbici<lc. has also b("cn r("gistcreti tOr u.'\c in irrigJtion 

eanJls and rcscn·oirs under Fll:R.-\ Scc1ion 24(c) in n1ultiplc states such 35 California. Indianan. · 

Oregon. :'lnJ Urnh (Nf'll{S. 2015). 1\erolcin ·s site of action has not been cln .• --silieJ by 1hc 

11crbicide l~csistancc 1\ction Comn1i11cc: or 1he \\•\.-cd Science Society of i\n1crica (\\,.SS1\ ) 

(Hlt·\C. 2015: WSS,\. 2015). 

13EJ\D prcp;ire<l 1:1 sununa.ry of acrolcin ahem.:sti\'eS and a discussion of un..:crtointics in 2008 

(El"•:\ . 2008a). :\t that time. OE1\D ,,.:JS unubh: l<t i<lcnti('' \\'01kablc chcn1ical ahema1ivcs to 

ncrolcin iOr '''cc:J Cl)lltrol in irrig,ntion canals. There '''ere mcchnnicnl ruc:ins of e<lntrol 

identified. such n.s chnining cnnnls. but 1hose arc potent !~· n1orc e.1o;pcnsi,·c than ncrolcin, ht:1\'c 

risks. of accidents to ,,·orkers. and ma)· make ii dillicuh 10 n11.•c1 '''ah!r qua lit~· standards. The 

summlll)' of n'-'roh:in :1h.:rna.1i\'CS nekno,vlcdgc in1ponant uncertainties. ;ind rcqucstc<l conu11cnt' 

fron1 irrigation profes.sion;1ls on 1hc in1p<irtnncc: l''.lf aerolein and a1tcn1ati\·cs: these '''ere 

sun1n1.arizcd in nnother BE1\D docun1cnt (EP :\ 2008b). The con1mc:nts i:onlirrnc:.·J thlt 

mechanical methods '"ere n1on: expensive lh:tn ncrolcin. and eau.'\cd n1orc dan1:igc to earthen 

lint'tl cunnls. 141!1\I) asked a.bout nhcrnati\'es. :ind rc-cci,·ed con1n1cnts on sc,·cr..11. bul all of1hc-sc 

,,·ere identified \\i th <lifficultics substituting tOr ncroll.'in - high..:-r use rntcs. highcr cost long 

required contact tin1c. poor eon1rol or re<iuir .. "(f holding ti1nc in the canal nt)cr a1,p1ication \\'ere 

typical 'on1p nL~. 

·111 .. •f\.' have co no BE1\ D benefits asscssn1cn1s or l)E,,\ 0 n,'\.,"CS:-.'tt11:-nl~ lbr 1:11:R1\ Section IS 

cn1crgcnc)· cxcrnp1ion rl.'qucsts tOr acrolcin in the Jast J 0 years. \\'hilc :ln cntcrt:cncy cxcn1p1ion 

rcquc-st nta)' )icld infonnation :tbout :i cl11.'1nical·s in1pon:incc or \';;tluc that is nol found in (lthcr 

EP1\ records. th!! l:ick of :i FIFR.t\ Sc-ctlon 1 S asscss1ncnt b)' T\1 ~1 ) docs not spcciftenlly indicate 

the rcl:ili\'c importance of this chcrni..:al. 

Qu:intitati\•e us.age inlOm1111ion tbr ncroll.'in is not available. cxccpl th~ 1 ;: ppro~i rn ttcl~' -0nc 

million pounds ofncti\·c ingredient ,,·ere sold annu;11ly (EP1\. :?008c). Oh1aining the tOllo\\'ing 

infontl:ttion n1a.y in1pro,·c futu~ assessments rl.'ln1('(( 10 the tL<;c :ind importance of acrolcin: I) 

total pounds of ncti,·c ingrcdic11t 3pJ1licd per year on a national ;ind/or rcg.iOnl l basis: :2) 

opplicntion rJt("S: tyμic.al and ma.xin1un1: 3) th.-qucney ::ind intervals of application: ;ind .i) 

eOicac)· infonn:11ion.'prt-xluct pcrfom1ancc. 
REFERENCES 

EP1\ . 2008:1. 1\crolcin 1\llcmntivcs 1\ss.:s..<i> 111..:-nt Sun101al')' and Unccnaintics (DP#3346SO). 

iv1orch 16, 2008. 

EP1\ 200Sb. Responses 10 Ct)tnrnC"nts J{ecei\'Cd on the 1\crolcin Rcrci;istr.tlion 1: tig_ibilil)' 

Decision (DP# 353791 ). 1\ugus1 27. 2008. 

EP.-\ . 2008<.:. Rcn:gistration li gibi lit~· Decision · .i\crolcin. Unilcd Slltlc!\ En\'ir(lnn11.'ntol 

Prolcction Agency. 1\ cccsst.'tl l:iy 2015 :it 

ht 1 p :/ /\\'\\'\\' .cp;1. go,·/pcsl ic idc:v'rcri:g is I r.11 ion:'R lil>..,::icrQ.l c i n_ t'-''-Llxi r'. 

I llt1\C. 2015. ('ln.o;silication of Herbicides 1\ccording to Site of 1\ ction. 1 lcrbic.:i<lc Rc ~t:lnC I.' 

:\ ction Co1nrni11cc: (I IR1\C). 1\cccsscd i\lay 2015 at http:l/hr.u:sll'lh.1l.co111/. 

I.UIS. 201 4. The Labd Use lnfonnOlion Sysicm (LUIS) Rcp011 for 1\crolcin. Augus1 26. 201 4. 

Biological and Econon1ic An:ilysis l>ivision. El''J\ Ot)icc of Pcs1icidc Progran1s. 

NPIRS. 2015. Fl.'dcral :ind s-1acc rl.'gis1ra.tion$. l\\1tion.:il Pesticide lntOrmation Rctricvul Sys1c111 

{Nl"'IRS). 1\cccsscd fay 2015 at hllp:!.'npirs.ccris.nurJ uc.l.'(lu. 

PPLS. 2015. EP1\ -;1pprovcd 1"--ehni<:i:tl CLnJ ..:n u.~ jlroducL<;/label$ $UCh as ~· agnic dcT'.'.r H 

llcrbicidc and la ni Tr.t B f\.licrobiocidc. The Pesticide Product :t~I S)'$lClll 

(PPLS). Accessed May 2015 01 

hup://\\ """ gs,1\ pc:~ti._ci_< ~$.'Chc: n M::trchfJ'!)Js:'O I (1707 -C.>00(1Q.:!0 l-l07 3 I .pd f and 

h11p://\\'\\'\\').cpa.go\'/P£sticidcs/c;hcm sc~1n,;J ppJ~ :'O 10707-C)OO I tl 201 ~ 1211.pdl'. 

\\"SS:\. 2015. R..:sistancc \\'e"">.lfs. \\1c-cd Science Society of 1\n1crica (\\'SS,\). 1\ccc-s.scd ri.·fi.1y 

2015 ::ii h1tp;//,\'Ccds.cicncc,l"1rg.i:::ulnn1:10.b11t.!f1.rt.'>N.