<PAGE>
                                                                   EXHIBIT 10.01


                          EIGHTH AMENDMENT TO AGREEMENT

         This Eighth Amendment ("EIGHTH AMENDMENT") is made by and between Atrix
Laboratories, Inc. a Delaware Corporation ("ATRIX"), with its principal place of
business at 2579 Midpoint Drive, Fort Collins, Colorado 80525-4417, and Block
Drug Corporation, a New Jersey corporation ("BLOCK"), with its principal place
of business at 105 Academy Street, Jersey City, New Jersey 07302-9988, effective
this 24th day of August, 2001 (the "AMENDMENT EFFECTIVE DATE"). Atrix and Block
are sometimes referred to collectively herein as the "PARTIES" and individually
as a "PARTY".

         WHEREAS, the Parties entered into an agreement dated December 16, 1996,
as amended by (i) the First Amendment to Agreement dated as of June 10, 1997,
(ii) the Second Amendment to Agreement dated as of July 31, 1997, (iii) the
Third Amendment to Agreement dated February 4, 1998, (iv) the Fourth Amendment
to Agreement dated as of January 12, 1999; (v) the Fifth Amendment to Agreement
dated as of January 27, 1999, (vi) the Sixth Amendment to Agreement dated as of
September 24, 1999, and (vii) the Seventh Amendment to Agreement dated as of
April 20, 2001 (collectively the "AGREEMENT").

         WHEREAS, the Parties desire to further amend the Agreement on the terms
and conditions set forth herein.

         NOW THEREFORE, for good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the Parties hereby amend the
Agreement as follows:

1. LICENSE GRANTS.

         (a) Block hereby grants to Atrix, for a period commencing on the
Amendment Effective Date through the end of the Term (the "SUBLICENSE PERIOD"),
an exclusive, except as to Block during the Transition Period (as defined below)
irrevocable right and sublicense, including the right to grant sublicense
rights, to (i) market, promote, advertise, distribute, commercialize, sell and
manufacture the Products in the Territory during the Sublicense Period, and (ii)
to any and all Improvements to the Products for use in the field of dentistry,
including all of its specialties (the Sublicense to be identical in scope and
duration to the License granted to Block under the Agreement).

         (b) Atrix hereby grants to Block, for the period commencing on the
Amendment Effective Date through the end of the Transition Period, a
non-exclusive, irrevocable, royalty-free limited right, without the right to
sublicense, to use the Marks (as defined below) solely in connection with the
marketing, promotion, advertising, distribution, commercialization and sale of
the Products in the Territory.

2. DEFINITION OF "TERM". Section 7.01 of the Agreement is hereby deleted and the
following language shall be inserted in lieu thereof:

                  "Section 7.01 Term. This Agreement will commence on December
         16, 1996 (the "EFFECTIVE DATE") and will terminate on August 24, 2005
         (the "TERM")."


                                       1

<PAGE>


3. TRANSFER OF ASSETS AND GRANT OF SECURITY INTEREST.

         (a) As soon as practicable after the Amendment Effective Date, but no
later than fifteen (15) days after the Amendment Effective Date, Block shall
provide and deliver to Atrix copies of the "SALES AND TARGET DISTRIBUTION" list,
[ ]** No later than thirty (30) days after the Amendment Effective Date, Block
shall provide and deliver to Atrix all instructional materials and Marketing
Materials (and any associated copyrights), sales and marketing data, to the
extent that such are directly related to the Products or the marketing,
advertising, sale, distribution and promotion of the Products, and only to the
extent thereto. Within ten (10) days of Atrix entering into an agreement with a
third party relating to the marketing, sale, distribution and promotion of the
Products, or at least thirty (30) days prior to the end of the Transition
Period, whichever is earlier, Block will transfer to Atrix complete and
unabridged copies of all customer lists and information directly related to the
Products and the marketing, sale, distribution and promotion of the Products,
[ ]**

         (b) Concurrently with the execution of this Agreement, for and in
consideration of the payments and other obligations herein contained, and
subject to the execution of the Security Interest Agreement set forth as Exhibit
B hereto (the "SECURITY INTEREST AGREEMENT"), Block shall transfer and assign to
Atrix all of Block's right, title and interest in and to (i) the trademarks
Atrisorb(R) and Atridox(R) and all associated trademarks, service marks,
slogans, trade names, copyrights, trade dress and the like (including the
associated goodwill of each) (collectively hereinafter referred to as the
"MARKS"), (ii) all Improvements to the Products, and (iii) all other rights of
Block with respect to the Products, whether acquired pursuant to the Agreement
or otherwise, except as otherwise set forth in this Agreement, in accordance
with the Assignment in the form attached hereto as Exhibit A (the "ASSIGNMENT").
Block represents that to the best of its knowledge, such Marks are free and
clear of any claims or encumbrances. Simultaneously with the execution of this
Eighth Amendment, Block shall execute and deliver to Atrix the Assignment.

         (c) Simultaneously with the execution of this Eighth Amendment, Atrix
shall execute and deliver to Block the Security Interest Agreement, pursuant to
which Block shall take a security interest in the Marks which provides that in
the event of a breach by Atrix of any of its obligations set forth in this
Eighth Amendment, all right, title and interest in the Marks shall revert back
to Block.

4. PAYMENTS BY BLOCK. Within three (3) business days after the Amendment
Effective Date, in consideration of Atrix entering into this Eighth Amendment,
the release granted by Atrix hereunder, and as full and final payment of all
amounts due or to become due as Milestone Payments pursuant to Section 3.02(b)
of the Agreement, Block shall pay to Atrix Three Million U.S. Dollars (U.S.
$3,000,000) (the "ATRISORB MILESTONE PAYMENT") in cash.

5. PAYMENTS BY ATRIX. In consideration of the Sublicense set forth in Section 2
hereof, the transfer of assets pursuant to Section 3 hereof, and the release
granted by Block hereunder, Atrix shall make the following payments to Block:

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** Confidential Treatment Requested



                                        2
<PAGE>


         (a) Three Million Three Hundred Thousand U.S. Dollars (U.S. $3,300,000)
in cash to be paid within three (3) business days after the Amendment Effective
Date; and

         (b) Three Million Seven Hundred Thousand U.S. Dollars (U.S. $3,700,000)
to be paid over a four (4) year period, as follows:

                  (i)      [ ]**

                  (ii)     [ ]**

                  (iii)    [ ]**

                  (iv)     [ ]**

                  (v)      [ ]**

For avoidance of doubt, in no event shall Atrix pay Block more than Three
Million Seven Hundred Thousand U.S. Dollars (U.S. $3,700,000) under this Section
5(b).

Atrix "NET SALES" for purposes of this Eighth Amendment shall have the meaning
given such term in the Agreement, substituting "ATRIX" for "BLOCK" therein.

6. WAIVER AND RELEASE [ ]**.

         (a) In consideration of the foregoing and subject to the terms of this
Section 6 and except for the obligations created by this Eighth Amendment, each
of Block and Atrix hereby releases, acquits and absolutely and forever
discharges the other Party hereto, its affiliates, and its and their officers,
directors, employees, agents, successors and assigns from any and all claims
(including royalty claims), debts, liabilities, demands, damages, accounts,
recordings, obligations, costs, attorneys' fees, expenses, liens, actions and
causes of action of every kind and nature, character and description, whether
now known or unknown, suspected or unsuspected, whether or not heretofore
brought before any arbitrator, local, state or federal court, agency or other
forum, related to the Agreement, occurring prior to or after the date of this
Eighth Amendment, related directly or indirectly to the Agreement including,
without limitation, the matters set forth in [ ]** except for (a) any claim by
either Party that arose prior to the Amendment Effective Date for which the
other Party is obligated to indemnify that Party as provided for in the
Agreement, (b) payment of any obligation due as provided under this Eighth
Amendment, or (c) any breach by either Party of that Party's obligations under
this Eighth Amendment.

         (b) Promptly upon Atrix's receipt of the Atrisorb(R) Milestone Payment,
each Party will take all necessary or required actions to dismiss its claims
against the other Party [ ]** and Atrix shall [ ]** Each Party shall [ ]**

7. TERMINATION OF ESCROW. As soon as practicable following the Amendment
Effective Date, the Parties shall take all action necessary, proper or desirable
to terminate the Escrow

----------

** Confidential Treatment Requested



                                        3
<PAGE>


Agreement and instruct the Escrow Agent to deliver all Documented Technology,
and any material Improvements or Know-How related thereto, held in escrow
pursuant to Section 10.03(a) of the Agreement to Atrix.

8. TRANSITION PERIOD. For the period commencing as of the Amendment Effective
Date, and terminating on [ ]** (the "TRANSITION PERIOD"), the Parties shall
abide by the following obligations:

         (a) Block shall cooperate with and assist Atrix in the complete
transition to Atrix of the marketing, promotion, advertising, distribution and
commercialization of the Products within the Territory.

         (b) Block shall use its reasonable best efforts to continue to market,
promote, advertise, distribute and commercialize the Products pursuant to the
Marketing Plan set forth as Exhibit C, subject to Atrix' rights to promote and
sell the Products during the Transition Period. The incremental costs of any
activities requested by Atrix beyond those set forth in Exhibit C shall be borne
by Atrix.

         (c) Block shall continue to abide by its royalty payment and accounting
reporting obligations as set forth in the Agreement during the Transition
Period. Block shall not be required to make any Milestone Payments following the
Amendment Effective Date, except as provided in Section 4 of this Eighth
Amendment. Block shall use its reasonable best efforts [ ]** Block shall not be
required [ ]** Block shall provide copies of such documentation within ten (10)
days of Atrix's written request.

         (d) In the event that Atrix enters into an agreement with a third party
pertaining to the sublicensing, marketing, promotion, advertising, distribution,
commercialization, sale and development of Products, Atrix shall ensure that
such third party does not engage in any such activities with Block's customers
disclosed on the customer list provided to Atrix hereunder prior to the
expiration of the Transition Period.

         (e) Block shall provide Atrix with copies of all information and
materials related to the marketing, promotion and/or distribution of the
Products, and only to such extent, including but not limited to any proposed or
adopted marketing and/or promotional campaigns for the Products.

         (f) Block shall not be permitted [ ]** Block will not [ ]** All [ ]**
under the Agreement [ ]** Block shall continue [ ]** Atrix shall [ ]** Block
shall [ ]** Any costs incurred [ ]**

         (g) Any Product purchased by Block under the Agreement and not sold or
otherwise distributed by Block prior to the expiration of the Transition Period
will be purchased by Atrix as follows: (i) Atrix shall pay to Block [ ]** (ii)
Block shall [ ]** (iii) the Products and Professional Samples [ ]** and (iv)
shall be shipped to Atrix appropriately packaged and stored, [ ]** All
transportation costs in connection with such sale, including without limitation,
insurance, freight

----------

** Confidential Treatment Requested



                                       4
<PAGE>


and duties, [ ]** Amounts owed [ ]** pursuant to this subsection (g) for the
Products or Professional Samples shall be paid [ ]**

         (h) During the Transition Period, Block shall, at Block's sole expense,
be responsible for that portion of ADE data collection activity that occurs
between Block and the patient or dental professional, as appropriate, including
any follow-up inquiries which Block deems necessary or appropriate.

         (i) Each Party shall maintain such facilities as are reasonably
necessary to carry out the activities to be performed by such Party pursuant to
the terms and provisions of this Eighth Amendment. Upon reasonable advance
notice, each Party agrees to make its employees and non-employee consultants
reasonably available at their respective places of employment to consult with
the other Party on issues arising during the Transition Period and in connection
with any request from any regulatory agency, including, without limitation,
regulatory, scientific, technical and clinical testing issues, provided that any
expense related to such consulting activities, including any travel and living
expenses associated therewith, shall be borne by the Party that incurs them.

9. TRANSITION SALES. If during the Transition Period:

         (a)      Atrix [ ]** then Atrix shall [ ]**

         (b)      Block [ ]** then Block shall [ ]** or

         (c)      Block [ ]**

10. RIGHT TO AUDIT. The Parties shall each complete a final accounting of all
sales of Product and shall provide such report to the other Party within
forty-five (45) days of the expiration of the Transition Period. In the event
that a Party disputes such report, that Party shall provide the other Party
written notice within thirty (30) days of that Party's receipt of such report.
The other Party shall permit an independent certified public accounting firm of
nationally recognized standing selected by the requesting Party, and reasonably
acceptable to audited Party, at the requesting Party's expense, to have access
during normal business hours to such of the records of the audited Party as may
be reasonably necessary to verify the accuracy of the sales reported by each
Party under Section 9 above. The accounting firm shall disclose to the
requesting Party only whether the sales reports are correct or not and the
specific details of any discrepancies. No other information shall be shared. If
such accounting firm concludes that the sales figures reported under Section 9
above were inaccurate, the audited Party shall reconcile its figures and remit
any amounts due and owing to the other Party within thirty (30) days of the date
the requesting Party delivers to the other Party such accounting firm's written
report so concluding. The fees charged by such accounting firm shall be paid by
the requesting Party, provided, however, that if the audit discloses that the
sales figures reported were discrepant by more than [ ]**, then the audited
Party shall pay the reasonable fees and expenses charged by such accounting
firm.

----------

** Confidential Treatment Requested



                                       5
<PAGE>


11. PROJECT LEADERS. Each of Atrix and Block shall designate and appoint a
person to coordinate and be the primary contacts between the Parties with
respect to implementing and carrying out activities during the Transition
Period. Each Party may replace its project leader at any time upon written
notice to the other Party.

12. TERMINATION OF DISTRIBUTION, PAYMENT AND REPORTING OBLIGATION.
Notwithstanding anything contained in the Agreement or this Eighth Amendment to
the contrary, from and after the expiration of the Transition Period, Block
shall not market, promote, advertise, distribute or commercialize the Products,
and Block shall not be required to make any royalty or other payments, or
deliver Royalty Statements or other reports, to Atrix with respect to periods
commencing from and after the expiration of the Transition Period (subject to
Atrix's rights set forth in Section 10).

13. EFFECT ON AGREEMENT.

         (a) As of the date hereof, the following Sections of the Agreement
shall be deleted and of no further force or effect: Articles VI, X, XVII,
Sections 2.01(b), 2.02, 2.03(b), 2.04, 3.03, 7.02 (a), 7.02(b), 7.03, 7.05, the
second and third paragraphs of Section 7.07, 7.08(b), 8.01-8.07, 8.09, 8.10,
8.13, the last two (2) complete sentences of Section 8.14, 9.01, 9.05,
14.01-14.06, 16.02, 16.06, 16.07 and 19.13, 19.17.

         (b) As of the expiration of the Transition Period, the following
Sections of the Agreement shall be deleted and of no further force or effect:
Article IX, Sections 3.07, in Section 8.08 the clause beginning . . . provided
however . . . through the end of Section 8.08, 11.07, 13.01-13.03, 13.06, 14.09,
14.10, 14.11, 16.08, and 19.10.

         (c) Except as expressly modified by the terms of this Eighth Amendment,
the terms and provisions of the Agreement shall remain in full force and effect
as originally written.

14. EXPENSES. The Parties shall each bear their own costs and expenses
(including attorneys' fees) incurred in connection with the negotiation and
preparation of this Eighth Amendment and consummation of the transactions
contemplated hereby. Atrix shall assume all costs associated with the perfection
and recordal of the documents related to the assignment of the Marks from Block
to Atrix. Atrix shall be responsible for all litigation costs incurred in
connection with its use of the Marks during the Transition Period, and any and
all litigation costs concerning the Marks occurring after the Transition Period,
except for litigation costs related to Block's use of the Marks at any time
prior to the termination of the Transition Period, which costs shall be Block's
responsibility.

15. PUBLICITY. The Parties shall not publish or make any statements about each
other that are disparaging and, no public announcement or other disclosure to
third parties concerning the existence of or terms of this Eighth Amendment
shall be made, either directly or indirectly, by either Party, except as may be
legally required or as may be required for financial reporting purposes, without
first obtaining the prior written approval of the other Party hereto and
agreement upon the nature and text of such announcement or disclosure. Each
Party shall review and respond with specific comments to public announcements
and disclosures by the other Party within five (5) business days of receipt of
printed copies thereof, or such proposed



                                       6
<PAGE>


announcement or disclosure shall be deemed approved. The terms of this Eighth
Amendment may also be disclosed to: (a) government agencies where required by
law, including filings required to be made by law with the United States
Securities and Exchange Commission ("SEC"), national securities exchanges or the
Nasdaq Stock Market, (b) a third party in connection with the license of the
Licensed Products, or (c) lenders, investment bankers and other financial
institutions of its choice solely for purposes of financing the business
operations of such Party, so long as such disclosure in (b) and (c) above is
made under a binder of confidentiality at least as restrictive the
confidentiality provisions in Article XVIII of the Agreement, so long as highly
sensitive terms and conditions such as financial terms are extracted from the
Agreement (including in any disclosure required by law or the SEC) or deleted
upon the request of the other Party, and so long as the disclosing Party gives
reasonable advance notice of the disclosure under the circumstances requiring
the disclosure.

16. MISCELLANEOUS.

         (a) All capitalized terms used and not otherwise defined herein shall
have the same meanings as set forth in the Agreement.

         (b) This Eighth Amendment may be executed by the Parties in
counterparts, each of which shall be deemed to be an original, but all such
counterparts shall constitute one and the same instrument, and all signatures
need not appear on any one counterpart. The Parties may execute this Eighth
Amendment by facsimile signature.

         (c) The Parties shall each perform such acts, execute and deliver such
instruments and documents and do all such other things as may be reasonably
necessary to accomplish the transactions contemplated by this Eighth Amendment.

         (d) Nothing in this Eighth Amendment shall be construed to make the
relationship of Block and Atrix herein a joint venture, association or
partnership or make the Parties agents of one another. The Parties are not
authorized to act as agents of one another as to any matter or to make any
representations to any third parties indicating or implying the existence of any
such agency relationship.

         (e) This Eighth Amendment constitutes the entire agreement between the
Parties relating to the subject matter hereof and supersedes any and all
previous agreements and understandings, whether written or oral. No terms or
provision of this Eighth Amendment shall be varied or modified by any prior or
subsequent statement, conduct or act of either of the Parties, except only in
the event that the Parties amend this Eighth Amendment by written instruments
specifically referring to and executed in the same manner as this Eighth
Amendment.

         (f) Each of Block and Atrix acknowledges that it has been represented
by counsel in the negotiation of the terms of this Eighth Amendment, and that it
has reviewed the terms of this Eighth Amendment with said counsel, and that its
decision to enter into this Eighth Amendment is based on the advise of said
counsel. Each of Block and Atrix further acknowledges that it is executing this
Eighth Amendment on a voluntary basis, and that it fully understands its final
and binding effect.



                                       7
<PAGE>


         (g) Each of Block and Atrix shall remain solely responsible for their
own tax obligations arising under the transactions contemplated by this Eighth
Amendment.

         IN WITNESS WHEREOF, the Parties hereto have caused this Eighth
Amendment to be duly executed by their respective authorized officers as of the
date first written above.

ATRIX LABORATORIES, INC.                        BLOCK DRUG CORPORATION

By:  /s/ Charles P. Cox                         By: /s/ DONALD F. PARMAN
   --------------------------------                ----------------------------
     Charles P. Cox, Ph.D., MBA                 Name: Donald F. Parman
     Senior Vice President,                          --------------------------
     Corporate Development                      Title: Secretary
                                                      -------------------------





                                       8

<PAGE>


                                    EXHIBIT A
                                       TO
                                EIGHTH AMENDMENT

                                   ASSIGNMENT

         WHEREAS, Block Drug Corporation (hereinafter "Block"), a New Jersey
corporation with a business address of 105 Academy Street, Jersey City, New
Jersey 07302-9988, is the owner of the trademarks and trademark registrations
for ATRIDOX and ATRISORB (hereinafter "the Marks") as set forth in Attachment A
hereto, and WHEREAS, Atrix Laboratories, Inc., (hereinafter "Atrix"), a Delaware
corporation with a business address of 2579 Midpoint Drive, Fort Collins,
Colorado 80525-4417, is desirous of acquiring said Marks and the registrations
therefor in the United States and Canada, and any other associated intellectual
property rights that are not specifically set forth in Attachment A, such as
trade dress, copyrights and other intellectual property owned by Block and
associated with the Marks;
         NOW, THEREFORE, for good and valuable consideration, the receipt of
which is hereby acknowledged, Block does hereby assign to Atrix all right, title
and interest in and to the Marks, together with any other associated
intellectual property rights that are not specifically set forth in Attachment
A, such as trade dress, copyrights and other intellectual property owned by
Block and associated with the Marks, and the goodwill of the business symbolized
thereby, subject to the Security Interest (as set forth in Exhibit B) in such
Marks granted by Atrix to Block as of even date herewith.


                                            BLOCK DRUG CORPORATION


                                            By: /s/ DONALD F. PARMAN
                                               --------------------------------

                                            Title: Secretary
                                                  -----------------------------

                                            Date:  August 24, 2001







                                  Exhibit A-1


<PAGE>


                                  ATTACHMENT A
                                       TO
                                    EXHIBIT A
                                       TO
                                EIGHTH AMENDMENT

                                   ATRIX MARKS


                  TRADEMARK ROSTER (01) (GROUPED BY TRADEMARK)

<Table>
<Caption>

ATRIDOX
-------

COUNTRY            CLASSES   APP. #       APP. DT        REG. #     REG. DATE   REGISTERED. OWNER             CURRENT STATUS
-------            -------   ------       -------        ------     ---------   -----------------             --------------
<S>                <C>       <C>          <C>            <C>        <C>         <C>                           <C>
Canada                       850,064      07/07/1997     530,394    21/07/2000  Block Drug Corporation        Registered

United States      5         75080259     28/03/1996     2219251    19/01/1999  Block Drug Corporation        Registered

ATRISORB
--------

COUNTRY            CLASSES   APP. #       APP. DT        REG. #     REG. DATE   Registered. Owner             CURRENT STATUS
-------            -------   ------       -------        ------     ---------   -----------------             --------------

Canada                       824,209      25/09/1996     511,768    12/05/1999  Block Drug Corporation        Registered

United States      10        75081223     29/03/1996     2135253    10/02/1998  Block Drug Corporation        Registered

United States      5         74102606     02/10/1990     1912165    15/08/1995  Block Drug Corporation        Sec. 8/15 Accepted
</Table>



                                  Exhibit A-2


<PAGE>


                                    EXHIBIT B
                                       TO
                                EIGHTH AMENDMENT

                           SECURITY INTEREST AGREEMENT


FOR GOOD AND VALUABLE CONSIDERATION, the receipt and sufficiency of which are
acknowledged, Atrix Laboratories, Inc., a Delaware Corporation ("Atrix"), with
its principal place of business at 2579 Midpoint Drive, Fort Collins, Colorado
80525-4417, hereby assigns, grants and mortgages to Block Drug Corporation, a
New Jersey corporation ("Block"), with its principal place of business at 105
Academy Street, Jersey City, New Jersey 07302-9988, a security interest in all
of Atrix' right, title and interest in and to the trademarks and trademark
registrations (the "Marks") set forth in Attachment A to this Agreement,
attached hereto.

THIS AGREEMENT is entered into to secure the full and prompt performance and
payment of all the obligations of Atrix, as set forth in the Eighth Amendment to
Agreement between Atrix and Block dated as of even date herewith. Upon the
satisfaction of all payments to Block from Atrix as set forth in the Eighth
Amendment to Agreement, Block shall, upon such satisfaction, execute,
acknowledge and deliver to Atrix such statements, documents or other instruments
in writing as may be reasonably requested by Atrix releasing the security
interest and mortgage in the Marks granted under this Agreement.

UPON the occurrence and during the continuance of any default by Atrix of the
obligations set forth in the Eighth Amendment to Agreement, Block shall have the
right, without notice to or consent by Atrix, to implement and record the
Assignment of the Marks back to Block as set forth in Exhibit 1 to this
Agreement, attached hereto.

The undersigned have executed this Agreement as of the date first above written.


ATRIX LABORATORIES, INC.                        BLOCK DRUG CORPORATION

By: /s/ CHARLES P. COX                          By:  /s/ DONALD F. PARMAN
   --------------------------------                ----------------------------
     Charles P. Cox, Ph.D., MBA                 Name: Donald F. Parman
     Senior Vice President,                          --------------------------
     Corporate Development                      Title: Secretary
                                                      -------------------------


                                  Exhibit B-1
<PAGE>


                                  ATTACHMENT A
                                       TO
                                    EXHIBIT B
                                       TO
                                EIGHTH AMENDMENT

                                   ATRIX MARKS

                  TRADEMARK ROSTER (01) (GROUPED BY TRADEMARK)


<Table>
<Caption>

ATRIDOX
-------

COUNTRY            CLASSES   APP. #       APP. DT        REG. #     REG. DATE   REGISTERED. OWNER             CURRENT STATUS
-------            -------   ------       -------        ------     ---------   -----------------             --------------
<S>                <C>       <C>          <C>            <C>        <C>         <C>                           <C>
Canada                       850,064      07/07/1997     530,394    21/07/2000  Block Drug Corporation        Registered

United States      5         75080259     28/03/1996     2219251    19/01/1999  Block Drug Corporation        Registered

ATRISORB
--------

COUNTRY            CLASSES   APP. #       APP. DT        REG. #     REG. DATE   Registered. Owner             CURRENT STATUS
-------            -------   ------       -------        ------     ---------   -----------------             --------------

Canada                       824,209      25/09/1996     511,768    12/05/1999  Block Drug Corporation        Registered

United States      10        75081223     29/03/1996     2135253    10/02/1998  Block Drug Corporation        Registered

United States      5         74102606     02/10/1990     1912165    15/08/1995  Block Drug Corporation        Sec. 8/15 Accepted
</Table>




                                   Exhibit B-2


<PAGE>


                                    EXHIBIT 1
                                       TO
                                    EXHIBIT B
                                       TO
                                EIGHTH AMENDMENT

                                   ASSIGNMENT

         WHEREAS, Atrix Laboratories, Inc., a Delaware Corporation ("Atrix"),
with its principal place of business at 2579 Midpoint Drive, Fort Collins,
Colorado 80525-4417, is the owner of the trademarks and trademark registrations
for ATRIDOX and ATRISORB (hereinafter "the Marks") as set forth in Attachment A
hereto, and WHEREAS, Block Drug Corporation (hereinafter "Block"), a New Jersey
corporation with a business address of 105 Academy Street, Jersey City, New
Jersey 07302-9988, is desirous of acquiring said Marks therefor in the United
States and Canada;

         NOW, THEREFORE, for good and valuable consideration, the receipt of
which is hereby acknowledged, Atrix does hereby assign to Block all right, title
and interest in and to the Marks, together with the goodwill of the business
symbolized thereby.


                                              ATRIX LABORATORIES, INC.


                                              By:
                                                 ------------------------------
                                                    Charles P. Cox, Ph.D., MBA
                                                    Senior Vice President,
                                                    Corporate Development




                                   Exhibit B-3
<PAGE>


                                    EXHIBIT C
                                       TO
                                EIGHTH AMENDMENT

                                 MARKETING PLAN

During the Transition Period, Block shall perform the following marketing
activities:


                                      [ ]**





                                   Exhibit C-1