EPA Jacket 87276‐7
1

BPPD Old Active Ingredient Checklist 

New Product RegistrationlExisting Product Amendment 

Fast Track 0 PRlA Actions B650 0, B660 0, B670 0, B672 0, B680 0, B681 0, B7IOD, 

B720 0, B721 0, B730 0, B880 0, B881 0, B890 0, & B900 0 

EPA Reg. No.: RAL: Application Date: 

1. Application Form (EPA Fonn 8570-1) - signed & complete including package 

type? IF NO, STOP! Call applicant and have them correct application and 

2. If amendment, was final printed labeling received for previous action? IF NO, 

E-mail and 

3. Confidential Statement (CSF) EPA Form 8570-4 Basic Formula 0 Alten;ate 

b. 

d. 

e. Certified limits agree 40 CFR 158.175? Note that' 5 batch 

analysis differ from Section 158.175(b), limits based on batch analysis would need 

be 

Viability (if' 

NAD 

g. PC codes assigned on CSF for actives & 

codes noted for 

h. List I inert ingredient(s) present in the formulation? If YES, sure it is listed on 

i. Alternate 

alternate CSFs per 

40 CFR IS2.43(b)(3). 

NAD 

not require different labeling CSF or other 

• 

j. Source for a.i. is a registered pesticide? (When a proposed alternate or new basic 

formula involves a new registered manufacturing-use product as the active 

ingredient source it must be detennined whether the manufacturing-use products 

us'ed to fonnulate are similar enough to warrant use of existing product specific data 

as acute 

CSF list peanuts, tree nuts, milk, soybeans, eggs (including putrescent eggs), 

fish, crustacea, or wheat commodities? If YES, RAL must evaluate label directions 

1071. 

a) Selective NO, SKIP to note that data matrix 

should be used for the cite-aU method to indicate the companies to whom offers 

Data Matrix the the 
2

proposed amendment. Minimum Data Matrix for registration includes: product ,.-

specific acute toxicity, product chemistry, and efficacy data for public health pests 

claimed on label. 

c. Adequate product specific data submitted? 

d. Registered source used for active ingredient? IF YES, SKIP to ITEM 5. (If active 

ingredient is from a registered source (manufacturing~use product), generic data 

should be satisfied by registered source.) If NO or if use not supported by 

registered source, generic data is necessary. 1-

e. Data passed PR Notice 86~5 for fonnatting and MRID number assignment? 

f. Public copy of Data Matrix provided? (PRN 98-5) 

5. Certification with Respect to Citation of Data (EPA Form 8570·34): See 40 C R 152 .so:-

98 and PR Notice 98~5 [Note: Ifno data are required or submitted, fonn is not needed. This . s ofte hue 

forminor amendments.] .- a. Did applicant check a Method of Support? 

b. General Offer to Pay checked for Cite~all Method or Cite~all under Selective 

Method? 

c. Is the form signed and dated? 

d. Check fonn and Data Matrix; are Exclusive Use data cited from other sources? 

e. IF YES, is the required authorization letter included in application? 

6. Formulators Exemption (EPA Form 5870~27) 

a. If registrant is using a registered source active ingredient in the formulation 

(manufacturing~use product), is form filled out completely and signed? , 

NAD 1'- 7. Exclusive Use Notice Requirement Prior to Registration (Required per 40 

CFR 152.116, separate from permission of an exclusive use data submitter to rely on 

exclusive use data) 

I 

Is this an exclusive use active ingredient or mix of active ingredients (registered w/in 

last 10 yrs)? 

I If YES, go to a) or b) below. 1-

a. a) Has a notification of intent to register letter or email been sent to the exclusive 

use data submitter(s) at least 30 days before registration? (This notification is I 

required for all methods of data support except when the exclusive use data I 

submitter(s)' product is used to formulate and the formulator's exemption is 

claimed.) 

b. Has exclusive use data submitter requested during 30 day period the applicants' list 

of data requirements and method of compliance? 1'-

c. Has registrant submitted certification from exclusive use data submitter that 

submitter is aware of the application and does not object to the registration? .-

8. Science Review completed? Comments: I 

, 

, 

1 

i 

! 

I 

2 
3

Label Review 

File Symbol' . Date" f f Reviewer. .--

[Site/Use] [ Res lAg !Both 1 [Food INon·Food !Both .-~ [Tax Categories: 1 [ AcOra!: /AcDerm: fAc!nhl: /Eyelrr: fSkinlrr: DermSens: 1 

--- Label Requirement Acceptable Not Acceptable NfA Comments LRM3 

Recommendations ---

Restricted Use Pesticide ----- --- ----- Cn 6 

Product Name Pg 12-3 

Compny Name and Info Pg 15-1 

Identification Numbers Go 14 --- Net Contents Ch17 

Ingredients Statement Gh 5 --- Label Claims Pgs 4-5, 5-7 

11-10 & Ch 12 

Alternate Formula 5-12 --

-- Precautionary Statements 

Label Requirement Acceptable No' NlA Comments LRNi3 

Acceptable Recommendations 

KOROC 3-1 & 9 

7-3 &4 - ---- Signal Word Ch3Ch'7 

Ch 10 ---

General Heading Ch 7 

,.PRECAUTIONARY 

STATEMENTS= 

First Aid (PRN 20001-1) I Ch 3 & 7 

Hazards to Humans Ch 3, 7-3 

and Domestic Animals 

PPE (WPS) Ch7, Pg 7-

Engineering Controls 12 

Pgs 10-4 15 

User Safety Ch10 

Requirements 

User Safety Ch 10 

Recommendations 

Environmenta! Hazards Ch 8 

Physical and Chemica! Pg 3-4 

Hazards Ch 9 ---
4

---

Directions for USE {FiFRA Text, WPS plus Storage and Disposal 

Label Requirement Acceptable Not NfA Comments LRiVl3 

Acceptable Recommendations 

Header >Djrections for 10-16 

Use", 

Violation of Federal Law ]10-26,1':;-7 text 

WPS Text Ch 1O, 7 .. ] 

(PPE) 7-11 

Non-WPS Text 7-12, Cli 10 

--- Pesticide Storage and __ 111-16, Ch 13 Disposal 

Container Disposal & ; PRN 20C7-4 

Batch Code i ---

Directions for Use (General Instructions and Information) 

Label Requirement Acceptable Not NfA Comments LRIVI3 

Acceptable Recommendations 

General Instructions an::! 

Sub-Header --- Chemigation I Prohibition PRN -- RE] Pg 1O-20 ---

._-

Label Requirement Acceptable Not NfA Comments LRM3 

Acceptable Recommendations 

-- General Info. (non-site 

specific info. on uses. pests. 

mixing, and loading, tank mixing, 

etc.) 

General Precautions and 

Restrictions 

Directions for Use 

Directions for Application 1 ___ Warranty Information 

-- Consistency with label 12-6 

instructions ._-

Not false or misleading 

"The warranty section contains an overly broad statement concerning limitations of liability. As such, this 

statement may be misleading and may constitute misbranding under the Federal Insecticide, Fungicide and 

Rodenticide Act (FIFRA). It is suggested that the existing statement be preceded by the phrase, Ato the exte nt 

allowable by state law@, or othelWise qualified to make it clear that this warranly is not intended to be a 

statement of law which implies that the buyer has no legal rights to recover damages from the manufacturer if" 

he/she suffered a loss or iniury from the product and concludes that it would be futile to pursue what might in 

reality be a valid claim." . 
5

#- 2..724 -35 2. 

[ J indicates optional statements 

ZOECON RF-291 EMULSIFIABLE CONCENTRATE 

With [Contains] PRECOR®[vIGRen®] Insect Growth Regulator 

Lasts 210 days 

Makes 1 gallon of spray 

Treats 1500 square feet 

Breaks the flea life cycle 

To Prevent the Emergence of Adult Fleas Indoors 

ACTIVE INGREDIENT: 

(S)-Methoprene (CAS #65733-16-6) ......................................................................... 1.2% 

OTHER INGREDIENTS': ....................................................................................... 98.8% 

Total 100.0% 

* Contains petroleum distillates 

KEEP OUT OF REACH OF CHILDREN 

CAUTION 

See back panel for additional precautionary statements 

EPA Reg. No. 2724-352 

EPA Est. No.: 

Net Contents: 

1 

1§; © C E: ]? T lEi') 

I~R 5 2004 
6

INTRODUCTION: Zoecon RF-291 Emulsifiable Concentrate [contains the insect growth 

regulator, S-Methoprene, which] acts on the immature life stages of the flea, preventing the adult 

flea from developing. Flea eggs deposited on, and larvae crawling onto treated areas will not 

develop into adult fleas. Existing adult fleas and flea pupae are not affected. 

If a high population of adult fleas (the biting stage) is present, tank-mix with an adulticide of choice 

that is EPA registered and properly labeled for flea control. Use Zoecon RF-291 Emulsifiable 

Concentrate prior to the flea season as a preventative treatment. To prevent infestations before 

they start, apply Zoecon RF-291 Emulsifiable Concentrate prior to flea season. 

When applied to surfaces where fleas are found, such as carpets, upholstered furniture, and pet 

sleeping areas, Zoecon RF-291 Emulsifiable Concentrate prevents adult flea emergence for up to 

7 months [210 days J. 

Controlling fleas on pets is important to prevent introduction of adult fleas indoors. If fleas are a 

problem on pets, treat the pets with an effective EPA registered flea control product. 

PRECAUTIONARY STATEMENTS 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS - CAUTION: Harmful if absorbed through 

the skin. Causes moderate eye irritation. Avoid contact with skin, eyes, or clothing. Wash 

thoroughly with soap and water after handling. 

FIRST AID 

Call a poison control center or doctor immediately for treatment advice. 

If in eyes • Hold eye open and rinse slowly and gently with water for t5-20 minutes. 

• Remove contact lenses, if present, after the first 5 minutes, then continue 

rinsinq eye. 

If on skin or • Take off contaminated clothing. 

Clothing • Rinse skin immediately with plenty of water for 15-20 minutes. 

Have the product container or label with you when calling a poison control center or doctor, or 

going for treatment. You may also contact 1-800-[phone number] for emergency medical 

treatment information. 

NOTE TO PHYSICIAN: This product contains petroleum distillates. If swallowed: Immediately 

call a poison control center or doctor. Do not induce vomiting unless told to do so by the poison 

control center or doctor. Do not give any liquid to the person. Do not give anything by mouth to 

an unconscious person. 

[Note. First aid statement paragraph format may be used If space IS limited.] 

PHYSICAL OR CHEMICAL HAZARDS: Combustible. Do not use or store near heat or open 

flame. 

DIRECTIONS FOR USE 

It is a violation of Federal Law to use this product in a manner inconsistent with its labelingi . , , : . , . 

This product may not be used or referenced as a source of ingredient in the formulation, 

manufacture, or registration of any other products without prior written authorization from 

Well mark International. 

2 
7

METHOD AND RATE OF APPLICATION: Prepare a diluted spray solution with a final 

S-Methoprene concentration of approximately 0.007%, by adding 1 oz of Zoecon RF-291 

Emulsifiable Concentrate to 1 gallon of water. Partially fiU the mixing container with % gallon of 

water, add Zoecon RF-291 Emulsifiable Concentrate, shake well, and then add the remaining ~ 

gallon of water. Shake well before each use. When tank-mixing, follow the directions above 

except add the product to tank mix first, agitate, and then add Zoecon RF-291 Emulsifiable 

Concentrate, agitate and complete filling of spray tank, and agitate once more. 

Apply at a rate of 1 gallon of the diluted spray-solution per 1500 sq ft of surface area with any low 

pressure sprayer with a fan tip that is typically used for indoor applications. Treat all areas 

harboring fleas, including carpets, furniture, pet sleeping and bedding areas, and throw rugs. 

Treat under cushions of upholstered furniture. Avoid contact with treated surfaces until dry. 

When applying to upholstery where staining could be a concern, apply dilution to a smaU 

inconspicuous location to determine if possible staining could occur. Generally, RF291 

Emulsifiable Concentrate will not stain areas that would not be stained by water alone. 

STORAGE and DISPOSAL: Do not contaminate water, food, or feed by storage and disposal. 

Storage: Store in a cool place away from heat or open flame. Pesticide Disposal: Wastes 

resulting from the use of this product may be disposed of on site or at an approved waste disposal 

facility. Container Disposal: If empty: Do not reuse this container. Place in trash or offer for 

recycling if available. If partly filled: Call your local solid waste agency or 1-800-CLEANUP for 

disposal instructions. Never place unused product down any indoor or outdoor drain. 

WARRANTY AND CONDITIONS OF SALE: Seller makes no warranty, expressed or implied, 

concerning the use and handlin9 of this product other than indicated on the label. Buyer assumes 

aU risks of use and handling of this material when such use and handling are contrary to label 

instructions. 

PRECQR® Insect Growth Regulator and vlGRen® Insect Growth Regulator are registered 

trademarks of Wellmark International. 

Wellmark International 

Schaumburg IL 60173 

Made in USA 

[For information](For questions or comments] call1-800-XXX-XXX X or visit our Web site: 

www.zoecon.com . 

3 
ential Statement of Formula may be entitled to confidential treatment*
12

r~~---'---' -~-.--~-~----- -.~---

I 

f 

I 

t 

I 

I 

--. ,3.·' 

ISB'S Front-end PRIA Completeness Screen 

Draft 3; 10/25107 

EPA Receipt Date: NOV 18 2010 '. EPA Reg . .Num"~r:"f 71)7(:; ~ r 

.' .•.. c· ~ •. " 

. . ·•··· ..... Ch~k;Ji;j~f ri, . i ,;,. •. .. " .... , •... • ... ~."j;;.il\j/A . 

I Haothe PRIA Fee been Paid; is a copY, t t~e ~nec~ 'or .')( 

Pay. gOY receipl included in the '" .'. 

'S "nApplication FOI'm (EPA Form 8570.I)jncluded in. the . 

2 Submission Package, is it completely filled ouf and 'signed , ' , ' ;( including package type? . . 

.'. .' '. 

Is a Confidential Statement of Formula (EPA Form 8570· 

3 29) .Included in the Submission Package, is it completely X 

filled out and signed (boxes 1·21)? 

4 Is a Formulator's Exemption Statement (EPA Form 8570· 

27) Included in the Submission Package? I 

5 'S a Certification with Respect to Citation of Data (EPA 

Form 8570.34) Included in the Submission x: 

(, Is a Data Matrix (EPA Form 8570·35) Included in the 

Submission Package? . I 

7 'S a I ;ahellncluded in the . , >< 

X Arc Da~a Included in the 

• ... ?<-

9 ., ".~ . an 4, . ." 

.' ... ' '.>" 

.', . 

. .-' 

>: -- :-;,; . .-

, . '. ::' . ./ .. ,. .. '<.' 

'. -< . ~ ,', ,. , ' ',' " 

, ~ ____ ~ ~_ . ~~ .~" _~ __ ~ __ ." "~_~~~_~ __ ~ ~ ___ ~. _ ~_~::..:-~'~ __ .. ~. ___ ~ _______ .;£"~ ,_ -.---:.~~..c_::"_~'_'~"-. __ :.':~ __ .. _~, 
13

Material Sent for Data Extraction 

Reg. No. S7J1~/] 

Description: ,[;]'0(,-1 5-= r&~('2ce (;J~ TC;~ C%.nbk'..= 

~Material(s) Sent to Data Extraction contractors: 

( 0 Newly stamped accepted label Dated:_ 

o 

p 

o 

Notification Dated: __ 

New CSF Dated:~1V,l(k t¥J I ~:S (0<,1120/1') 

Other: 

o Decision #: _____ _ 

o Other Action/Comments: ___________ _ 

File this coversheet and attach materials in the jacket. It 

must be well organized and clipped together, NOT STAPLED. 

Then give the Jacket with the coversheet and materials inside, 

to Staff in the Information Services Center(ISC) (Room 8-4900) 

or place in the designated bin. If the Jacket is full or only 

available as an image, please file materials in a new jacket 

cover follow the same procedure as above. For further 

information, please call 703-605-0716. 

Reviewer's Name: _.LO/....l,a-'r£tiMv~~"'-· ____ _ 

Phone: 0D)~Jc{1 iV/b 

Date: i !l]~.9--('1 

Division: r3t!:D 

Created September 28, 2011 
14

$YMaOL 

~ , 

UNITED STATES ENVIRONMENTAL PROTEC .. ON AGENCY 

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D,C, 20460 

NOV 222011 

OFFICE OF CHEMICAL SAFETY 

AND POLLUTION PREVENTION 

Michael Kellogg, Agent 

Envincio LLC 

C/o Pyxis Regulatory Consulting, Inc. 

4110 1361h St, NW 

Gig Harbor, WA 98332 

Subject: Equil S-Methoprene 1.2% IGR Concentrate 

EPA Registration No, 87276·7 

CSF Amendment to replace alternate formulations # 1-3 dated January 13, 2011 and 

replace with alternate formulations # 1-3 dated April 20, 2011 

Decision #: 448218 

Application Dated: August 19, 2011 

Dear ML Kellogg: 

The amendment referred to above, submitted in connection with registration under FIFRA section 

3(c)(5), is acceptable provided that you submit and/or cite all data required for 

registration/reregistration of your product l.mder FIFRA section 3( c) (5) when the Agency requires 

all registrants of similar products to submit such data, The alternate Confidential Statements of 

Fonnula (CSFs) # 1·3 dated April 20, 2011, have been added to your file as current and updated, 

Please note that your alternate CSFs # 1-3 dated January 13, 2011 are considered outdated and 

obsolete. Should you have any questions, you may contact Ms. Menyon Adams directly at 

703.347.8496 or via email at adams.nIenvon!7l;epa.lLOv. 

I 

. ....... ......... - ................. 

Sijerely, (I I 

~ fcL1tJ- ol. 

Linda A. Hollis, Chief 

Biochemical Pesticides Branch 

Biopesticides and Pollution 

Prevention Division (7511 P) 

COHCURR!HCI!$ 

. ................ .................. . ................ . ................. ................. StlRNAME 

!\~ ..... . ... ................. ................. ................. ................. .. ............... .................. ................. DATE , II" I \ I 

EPA Form 132Q..1A 1190\ PTUuld 011 Rl IrdPa , OFFICIAL. FILE COpy 
15

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

OFFIC£ OF CHEMICAl SAFElY AND POLUTION PREVENTION/OHIC£ OF PESTICIDE PROGRAMS 

MEMORANDUM 

DATE: October 11, 2011 

SUBJECT: Review of Registrant CSF Amendment Request in Support of the Registration of 

Equil S-Methoprene 1.2% IGR Concentrate, Containing 1.2% (S)-Methoprene As 

Its Active Ingredient. 

FROM: 

TO: 

Decision Number: 

DP Number: 

EPA Registration Number: 

Chemical Class: 

PC Code: 

CAS Number: 

448218 

393461 

87276-7 

Biochemical 

105402 

65733-16-6 

Active Ingredient Tolerance Exemptions: 40 CFR 180.1033 

MRlD Numbers: N/A 

Type of Review: Product Chemistry 

Biochemical 

SadafShaukat, 

Pesticides 

Biologist 

Brangu""'{,/ 

)0'// ~ ~ Biopesticides & Pollution Prevention Division (7511P) 

Menyon Adams, Regulatory Action Leader 

Biochemical Pesticides Branch 

Biopesticides & Pollution Prevention Division (7511P) 

ACTION REQUESTED 

Envincio LLC is proposing to replace two inert ingredients in the product formulation with two 

new inert ingredients. 
16

(S)-Methoprene 

PC Code: 105402 

RECOMMENDATIONS AND CONCLUSIONS 

1. The product chemistry submission is UNACCEPTABLE. 

DP Number: 393461 

EPA Reg. No.: 87276-7 

a. Both new inert ingredients* that the registrant wishes to add in the alternate 

formulation are now approved by the Agency as per the attached email 

correspondence between Elizabeth Fertich on behalf of the Inerts Branch and 

Mike Kellogg dated S/1911 1. The eSF's dated 4/2011 1 are acceptable. 

*See confidential appendix for more delails. 

STUDY SUMMARIES 

Product Chemistry 

No DER was created. 

The registrant submitted a new CSF with the proposed new alternate formulations. Both inert 

ingredients* proposed to be added are now approved by the Agency. The CSF's dated 4/20111 

are acceptable. 

*See confidential appendix for more details. 
17

(S)-Methoprene 

PC Code: 105402 

CONFIDENTIAL APPENDIX 

RECOMMENDATIONS AND CONCLUSIONS 

RECOMMENDATIONS AND CONCLUSIONS 

1. The product chemistry submission is UNACCEPTABLE. 

DP Number: 393461 

EPA Reg. No.: 87276-7 

a. Both new inert ingredients that the registrant wishes to add 

in the alternate formulation are now approved by the Agency as per the attached 

email correspondence between Elizabeth Fertich on behalf of the Inerts Branch 

and Mike Kellogg dated 8119/11. The eSF's dated 4/20111 are acceptable. 

STUDY SUMMARIES 

Product Chemistry 

No DER was created. 

The registrant submitted a new CSF with the proposed new alternate formulations. Both inert 

ingredients proposed to be added are now approved by the Agency. The 

eSF's dated 4/20111 are acceptable. 

cc: S. Shaukat, MAdams, BPPD Science Review File, IHAD/ARS 

S. Shaukat, FT, PY-S: 10111/11 

*Inert ingredient information may be entitled to confidential treatment*
18

Mike Kellogg 

From: 

Sent: 

To: 

Cc: 

Subject: 

Mr. Kellogg, 

Fertich.Elizabeth@epamail.epa.govon behalf of InertsBranch@epamail.epa.gov 

Friday, August 19, 2011 10:22 AM 

Mike Kellogg 

Shah.Pv@epamail.epa.gov 

RE: & 

We received the compositional information for and from Both 

compositions have been updated/added to our trade name database. The inert ingredient approval status follows: 

(pre- and post-harvest uses) (pre~ and post-harvest uses), 180.920 (post-harvest 

uses), & 180.930 (applications to animals) 

Please let us know if you encounter problems with your next (SF submittal containing these ingredients. 

Regards, 

liAS 

***Please direct all correspondence related to this email and all new inquires/comments to inertsbranch@epa.govand 

not to the individual sender ofthis email. All emails received by the sender will be forwarded to the 

inertsbranch@epa.gov . You assistance in this matter allows liAS to track the requests/questions/comments and to 

maintain a record of the information provided. *** 

From: InertsSranch 

To; Mike Kellogg <Mike@PyxisRC.com> 

(c; Pv Shah/DC/USEPA/US@EPA 

Date: 08/18/201102:36 PM 

Subject:RE: & 

Sent by: Elizabeth Fertich 

Mr. Kellogg, 

We will look into the issue regarding and get back to you assoon as possible. As for the composition for 

it may be mailed to liAS. The contact information and address are listed in Question 2S ofthe "Inert Ingredient 

Frequently Asked Questions" available on our website at http://www.epa.gov/opprd001/inerts/. 

Regards, 

liAS 

***Please direct all correspondence related to this email and all new inquires/comments to inef<'~bnnch@~pa ROV and 

not to the individual sender ofthis email. All emails received by the sender will be forwarded to th:-

inertsbranch@epa.gov . You assistance in this matter allows liAS to track the requests/questic.rs/.;omments and to 

maintain a record of the information provided. *** 

*Inert ingredient information may be entitled to confidential treatment* *Product ingredient source information may be entitled to confidential treatment*
19
20

I " OMA N,. .2·' .... United StotOli § Registration ow Idontifiar Number 

,sEPA Environmental Protection Agency .f Amendment 

Walhington, DC 20460 . Other 

for , , - , I 

r. Compllny/Product Numbsl 2. EPA Product Mllnllgar 3. Proposed CIlI$sificlltion 

87276-7 L. Holf;, o Nonll o Rostricted 

,'N.m,' PM. 

Concentrate 91 

5. Num .. lind Addross of Applicllfll/lncludo ZIP Coda) 6. Expedited Reveiw. In aCCOIdance with FIFRA Section 3(c)f3) 

Envincio LLC {b)fil, my product is similal or identical in composITion and labeling 

clO Pyxls Regulatory Consufling, Inc. to: 

41;~:~61hS'. NW EPA Reg. No, 

Gia ~ ~A 98332 

Chrck if this is tI new .dd,..:;:; tName 

, ,-II 

0 Amondmonl- Explain balow. U Final printud labol. In fI'p"on!tD to 

Agoney !ottor dilloci 

0 Rl,IGubminion in rO$POnSD 10 Agoney lotter dlllod 7/26/2011 0 ~M. TDO~ AppHclltion. 

0 NOli!icllti"n' Expillin b"'ow. 0 Othor - Eltploin bolow. 

, : Usa odditional PUII!,!!S! i/ nBCOUOry. (For $oction I .. nd Suction If.) 

Response!o Agency deficiency letter daled Ju!y 26,2011 (DecisJon#: 448218). 

:rn 

1 f. II .. ' ""' Child'Rolllstont Pockolling lu~~ I ~r solubl .. Pochging 2. Typu of Contoinor 

[2j'"' :z:J YII" 

.( No -'-;i N, I t2j N, 

Yo. ~M"" ,/ Philltic 

Glaps 

~~flftificstJon must ."." No.p" If -Yas· No.,,, pap,,; {Specify! 

flubmitted wgt. Packago wgt Othor . 

'0' 10 

[(J ~:;f N., 

, 14. "",.) Roo. 1 1 01 labol Oiroctions 

[.(1 10 x 1 fl. oz. and 16 fl. 0'. t±:l 0,",. , 

6. Munnor in Which labe! I. Affixod to Product 

l'~ 0 Othor 

-IV 

, Ifo hOI ' ... .,..- N~ "d, I To!ophono No. 1Irn:lud!l Aroo Codo> 

Michael Kellogg Agent (253) 853-7369 

Certification I', 

I conify th"t tha statomonts I hov!'! mado on this form end "II ettochmonto thoroto oro tntll, occurotll und comple~o: ' ) , 

I IICknowIOdoe_~~~~_n,~_knoWlin911y falsa Or misillading stotamont may bo punishllblo by finll or !mprisonment or ; , (StamPed) both undar " , ,': " , , 

,. ",O'"" £, 3. TItlll .. /1A';'. Agent 

N~, 5. Doto 

Michael Kellogg gln!lf ' )' 

,,. , , 'A ••. 3·94' P"",,, "''''0'' ." _ "El' ........ 'on""'" "-,, 
21

PYXIS REGULATORY CONSULTING, INC. 

4110 136m St. NW 

Gig Harbor, WA 98332 

COURIER DELIVERY 

Menyon Adams (BPPD) 

Document Processing Desk (AMEND) 

Office of Pesticide Programs (7504P) 

U.S, Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 S. Crystal Drive 

Arlington, VA 22202 

August 19, 2011 

Phone: 253-853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

RE: Envincio LLC - Equil S-Methoprene 1.2% IGR Concentrate (EPA Reg. No. 87276-7) 

Submission in Response to Agency Letter dated July 26, 2011 

Decision#: 448218 

Dear Ms. Adams, 

On behalf of Envincio LLC please let this letter serve as our response to the Agency deficiency letter 

dated July 26, 2011 for Envincio's Equil S-Methoprene 1.2% IGR Concentrate, The two inert ingredients 

listed in the Confidential Attachment of the July 26, 2011 letter have been approved by the Inerts Branch 

per the enclosed email confirmation. 

In support of this submission please find the following 

I. Completed Application for Amendment (EPA Form 8570~1) 

2. Copy ofemail correspondence from EPA Inerts Branch dated August 19, 2011 

Please feel free to call me if you have any questions or need any additional infonnation. 

J~ Michael Kellogg 

Enclosures 

" , , , " , 

" " 

" " , , 
22

DATA PACKAGE BEAN SHEET 

Date: 01-Sep-2011 

Page 1 of 1 

* * * Registration Information * * * 

Registration: 87276-7 - EQUIL S-METHOPRENE 1.2% IGR CONCENTRATE 

Decision #: 448218 

DP #: (393461) 

NON PRrA 

Parent DP #: 

Submission #: 902076 

E-Sub #: 

Company: 87276· =E~N~V~IN~C~IO"-,,L~LC,,--_____________________ _ 

Risk Manager: RM 91.. - Linda Hollis - (703) 308-8733 Room# PY1 S·8761 

Risk Manager Reviewer: Menyon Adams MADAMS07 

Sent Date: 23-Aug-2011 Calcula1ed Due Date: 21 -Nov-2011 

Type of Registration; Product Registration - Section 3 

Action Desc: (345) FORMULA CHANGE;TECHNICAl: 

Edited Due Date: ____ _ 

Ingredients: 105402, S-Metho~p~"~"~'~(1~.2~%~),--___________________ _ 

* * * Data Package Information * * * 

Expedite: 0 Yes. No Dale Sent: 01-Sep-2011 Due Back: ____ _ 

DP Ingredient: 105402, S-Melhoprene 

DP Title: _____________ _ 

CSF Inctuded: • Yes 0 No Label Included: • Yes 0 No Parent DP #: ____ _ 

Assigned To 

Organization: oB~P~P~D~I~B~P~B _______ _ 

Team Name: ~R~M~9~1 __________ _ 

Reviewer Name: ,JO~"~,~,.~R~o~'~"~II'-n ______ _ 

Conlractor Name: S_~~d~,~f-~ _____ _ 

Date In 

91-Sep-2011 

01-Sep-2011 

01-Sep-2011 

Date Out 

* * * Studies Sent for Review * * * 

No Studies 

Last Possible Science Due Date: 07-0ct-2011 

Science Due Date: 

Sub Data Package Due Date: ____ _ 

* * * Additional Data Package for this Decision * * * 

Can be printed on its own page 

* * * Data Package Instructions * * * 

Hi Russ, 

Please review. This is a response to Agency deficiency leiter daled July 26, 2011. This action considt of a CSF Amendment replacing CSF #'s 

1-3 with Alt CSF#'s 1-3<.D.J1.e.Date November 21, 2011. Review Due"Dale is OCtober'21, 2011. 

Thanks, 
23

BPPD FOr]II1t1ation Amendment Check List 

Fast Track ifand PRIA Actions B680 0, B681 D,B730D 

1. Application Form (EPA Form 8570-1) - signed & complete including package type? IF NO,_ 

STOP! Call and them correct and 

2, Final printed received for previous action? IF NO, STOP! E-mail applicant and 

final 

3. storage 

If so have the terms/conditions been met? /' 

4. Confidential of Formula (CSF) EPA Form 8570-4 Basic Formula 

e. Certified' I agree with 40 CFR 158.175? Note that if preliminary or 5 batch analysis 

from Section 158.1~ limits based on batch analysis would need to be proposed under Section 

158. 

f. microbial, i.e., 

g. assigned on CSF for 180.910,180.920, and 180.930 

noted for that have food or feed uses? 

h. List I inert fonnulation? 

k. 

do I)0t require different labeling from basic CSF or other alternate CSFs . 

. . I alternate or new basic involves 

a new registered manufacturing-use product as the active ingredient source it must be detennined 

or wheat 

180.1071. 

products used to I to warrant use of 

list peanuts, tree nuts, milk, soybeans, eggs (including putrescent eggs), fish, crustacea, 

If YES, RAL must evaluate label directions for compliance with 40 CFR 

5. Data and Data Matrix Fonn 

a. a) Using Selective Method? [[IF NO, SKIP to item 5 and note that data matrix should be used 

for the cite-all method to indicate the companies to whom offers of compensation were 

b. Data Matrix. Minimum Data Matrix for 

, and data for 

I 
24

d. Registered source used for active ingredient? IF YES, SKIP to ITEM 5. (Active ingredient is 

from a registered source and generic data should be satisfied by registered source. IF NO, generic 

data needed. 

e. Data passed PR Notice 86-5 for formatting and MRID number assignment? 

f. Public copy of Data Matrix provided? (PRN 98-5) 

6. Certification with Respect to Citation of Data (EPA Form 8570~34): See 40 CFR 152.80-98 

and PR N?tice 98-5 [Note: 1:00 data are requi:ed or sUbmitted,a ce~with Respect to Citation of 

Data form IS not needed. This IS often true for mmor amenjrnenls.J L 

a. Did applicant check a Method of Support? L~ 

b. General Offer to Pay checked for Cite-all Method or Cite-all under Selective Method? 

c. Is the fonn signed and dated? 

d. Check form and Data Matrix; are Exclusive Use data cited from other sources? 

IF :Vhe required authorization letter included in application? 

NA 

7. Formulators Exemption (EPA Form 5870-27) 

a. If registrant is usi~a,registered source active ingredient in the fonnulation, is form filled out 

comva--signed? 

NA 

8. Science Review completed? Comments: 

~m~~~~AtNV I 

Inlernal BPPD Guidance Document- Other Items May be Required 2 January 2010 
25

Ross Gilbert, Agent 

Envincio LLC 

"\ : 

jlTED STATES ENVIRONMENTAL PROT,-~ hON AGENCY 

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

clo Pyxis Regulatory Consulting, Inc. 

4110 136th St. NW 

Gig Harbor, WA 98332 

Subject: Equil S-Methoprene 1.2% IGR Concentrate 

EPA Registration No. 87276-7 

OFfiCE OF CHEMICAL SAFETY 

AND POLLUTION PREVENTION 

CSF Amendment to amend alternate formulations #'s 1-3 for the products registration 

Decision#: 448218 

Application Dated: April 20, 2011 

Dear Mr. Ross: 

The amendment referred to above, submitted in connection with registration under FIFRA 

section 3(c)(5), is not acceptable. The deficiencies in your application are listed in the Confidential 

Attaclunent to this letter, 

The labeling amendment requesting to aroend alternate product formulations #' s 1-3 has been 

reviewed by the Biopesticides and Pollution Prevention Division and the proposed amendment is 

unacceptable. By regulation, the Agency is obligated to give you 75 days (40 CFR 152.105) in 

which to address the deficiencies identified above, You will have 75 days from the date of this letter 

to submit the required information before the Agency will withdraw your application because it is 

incomplete. !fyou have any questions please contact Menyon Adams at 703-347-8496, or by email 

at adams.menyon@epa.gov. 

t::,Q~. Linda A. Hollis, Chief 

Biochemical Pesticides Branch 

Biopesticides and Pollution 

Prevention Division (7511P) 

CONCURRENCES 

SYMBOL E : ~'P.. ..... 1.0l! .. f.'.. .... .............................................................................................................................. . 

:~:AME ~ ·()ih~t> .. "iffiif ............................................................................................................................. .. EPA Form 132o-1A (1/90) Printed em Recycled Paper OFFICIAL FILE COpy 

"u.s.. Govonuncnt Ptintin~ 011\0", 2005 20~ I~) 
26

Confidential Attachment 

The product chemistry submission is UNACCEPTABLE. 

Both new inert ingredients that you wish to add in alternate formulatious 

#'s 1~3 are not approved by the Agency. You must contact the Inerts Branch in the Registration 

Division of OPP to seek approval for these ingredients. 

*Inert ingredient information may be entitled to confidential treatment*
27

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

OffICE Of CHEMICAL SAfETY AND POlUTION PREVENTION/OFfICE OF PESTICIDE PROGRAMS 

MEMORANDUM 

DATE: July 13,2011 JUL 1 3 10" 

SUBJECT: Review of Registrant CSF Amendment Request in Support of the Registration of 

Equil S-Methoprene 1.2% IGR Concen{rate, Containing 1.2% (S)-Methoprene As 

Its Active Ingredient. 

FROM: 

TO: 

Decision Number: 448218 

DP Number: 389168 

EPA Registration Number: 87276-7 

Chemical Class: Biochemical 

PC Code: 105402 

CAS Number: 65733-16-6 

Active Ingredient Tolerance Exemptions: 40 CFR 180.1033 

MRID Numbers: N/A 

Type of Review: Product Chemistry 

Biochemical 

Biopesticides 

SadafShaukat, 

Pesticides 

& 

Biologist 

Pollution 

Branch 

Prevention 

~ 

Division (7511P) 

Menyon Adams, Regulatory Action Leader 

Biochemical Pesticides Branch 

Biopesticides & Pollution Prevention Division (7511P) 

ACTION REQUESTED 

Envmcio LLC is proposing to replace two inert ingredients in the product formulation with two 

new inert ingredients. 
28

(S)-Methoprene 

PC Code: 105402 

RECOMMENDATIONS AND CONCLUSIONS 

1. The product chemistry submission is UNACCEPTABLE. 

DP Number: 389168 

EPA Reg. No,: 87276-7 

a. Both new inert ingredients* that the registrant wishes to add in the alternate 

formulation are not approved by the Agency. The registrant must contact the 

Inerts Branch in the Registration Division of opp to seek approval for these 

ingredients. 

*See confidential appendix for more details. 

STUDY SUMMARIES 

Product Chemistry 

No DER was created. 

The registrant submitted a new CSF with the proposed new alternate formulations. Both inert 

ingredients* proposed to be added are not approved by the Agency, and must be approved before 

a full review can ensue. 

*See confidential appendix for more details. 
29

(S)-Methoprene 

PC Code: 105402 

CONFIDENTIAL APPENDIX 

RECOMMENDATIONS AND CONCLUSIONS 

RECOMMENDATIONS AND CONCLUSIONS 

1. The product chemistry submission is UNACCEPTABLE. 

DP Number: 389168 

EPA Reg. No.: 87276-7 

b. Both new inert ingredients & that the registrant wishes to add 

in the alternate formulation are not approved by the Agency. The registrant must 

contact the Inerts Branch in the Registration Division ofOPP to seek approval for 

these ingredients. 

STUDY SUMMARIES 

Product Chemistry 

No DER was created. 

The registrant submitted a new CSF with the proposed new alternate formulations. Both inert 

ingredients & proposed to be added are not approved by the Agency, and must 

be approved before a full review can ensue. 

cc: S. Shaukat, MAdams, BPPD Science Review File, IHAD/ARS 

S. Shaukat, FT, PY-S: 7/13/11 

*Inert ingredient information may be entitled to confidential treatment*
30

\\~'U\ m\Q-\.o\ l\ 

fu~~ D41~1111. 

11c UAK.: DioliOLt 

lY}~ Ollf~I'1 

. LQ~ ITl/ fLj It; 
31
32

Fo I At roved. OMB No. 2070-0080. , .><Dl," '-'8-95 

. 

United Stotes O Registration 

.; Amendment 

Other 

OPP Identifier Number 

&EPA Environmental Protection Agency 

Washington, OC 20460 

Application for Pesticide - Section I 

,. Compony/Product Number 

87276-7 

4. Company/Product INomo) 

2. EPA Product Manugor 

L Hollis 

PM. 

3. Proposed Classification 

[2] None D Rostricted 

Envincio LLC I Equil S-Methoprene 1.2% IGR Concentrate 91 

5, Name and Addross of Applicant (Include ZIP Cod., 

Envincio LLC 

clo Pyxis Regulatory consulting, Inc, 

4110 136th 51. NW 

6. Expedited Reveiw. In accordance with FIFAA Section 3(e)13) 

lbj(il, my product is similar at identical in composition and labeling 

to: 

Giq Harbor. WA 98332 

EPA Reg. No. _______________ _ 

o Check if this is II new (lddrsS$ Product Name 

o 

o 

o 

Section - II 

Amendment - Expluin below. 

Resubmission in response to Agency lottor dated ______ _ 

u 

o 

o Notification - Explain below. 

Explanation; Use odditional poge{sl if nccessery. (For 5uction I and Section 11.) 

Anal printod lobolll in repsonse to 

Agoncy lottor doted 

"Mo Too" Applicotion. 

Other - Explain bulow. 

Submission of an amendment to Ihe Confidential Statement of Formula (Alternate Formulations 1-3). As no data are being submitted with 

this amendment, nor will data need to be reviewed to approve the proposed amendment, Envincio LLC believes this action qualifies as a Fas' 

Track amendment and is not subject to a Pesticide Registration Service Fee. Should you have any questions please contact me via email at 

Ross@PyxisRC.com or phone at (253) 853-7369. 

1. Motorial Thi, Product Wlll a. Peckaged In: 

Child-Rosislonr Pockeging 

DV" [2] No 

Unit Peckllging 

[7lV" 

[ZjNo 

If ~Yos~ No. por 

Section - III 

Wllter Soluble Peckoging 

D v., 

[{] No 

2. Type of Containor 

Gless 

Peper • C8rtification must 

bfJ submitted 

Unit Packaging wgt. container 

If ~Ye$" 

Peckogll wgt 

No. par 

containar 

E] ~:::lc 

Other !SpacifyJ ______ _ 

1 oz. 10 I 

3. Locetion of Net Contenls Information 

[{J lobel l.{J Contoiner 

6. Mennor in Which label is Affixed to Product 

4. SilO lsi Rotoil Containar 

10 X 1 fl. oz. and 16 fl. oz. 1

5. locotion of Label Oirections 

J - On Labol f:2j On Lab~linll accompanying product 

lJ Uthograph ./ Poper aluod 

StanciIGd 

Section - IV 

o Other __________ _ 

1. Contoct Point {Comp/Me ifums dirflcriy bolow for fdentificfltion of individual ro bo confoctBd, if nBcBssary, 10 procoss this opplicofion. ( 

Nome Title 

Agent 

Telephone No. IInclude Area Code) 

Ross Gilbert (253) 853-7369 

Certification 

I cenify thel the stolflments I have mode on this form ond all ottochments thoreto oro truo, occurote en<::! complete. 

I acknowledge that any kno wlinglly fllisa or mislollding stotomont moy be punish9ble by fine or imprisonment or 

both undor epplicablelew. 1-,-. s-;-,-"'-t-"-,,----'-'---------------r3-.-T1-'-tl.--------~--;-;-;-,-;-r--?' ,-.-'-j' t-11-\J1-eA-- Agent i . • . I 

4. TyPod Nllmo 5. Oatil 

Ross Gilbert 

6. Oete Applicetien 

Roceivttd 

(Stamped) 

. • • 

. • • • • · · · · • 

• 

, ) ,; , 

EPA Form 6570·1 IRev. 3-941 PreVIOUS editions are obsolete. White - EPA File Copy !oiiglniii ... Yellow· AppRc.nt Copy 
33

IFee for Servicel 

This package includes the following 

o New Registration 

@Amendment 

I 0 Studies? 0 Fee Waiver? 

I 0 volpay % Reduction: __ 

for Division 

OAD 

@BPPD 

ORD 

I Risk Mgr. 

I I 

{894333'-

Receipt No. s-:=I =8=94=3=3=3===: 

EPA File Symbol/Reg. No. :=1 ==87=2=7=6::::-7===: 

Pin-Punch Date: 1 4/21/2011 

ur This item is NOT subject to FFS action. 

Action Code: II, Parent/Child Decisions: I 

Requested: I ' 

Granted: LI ___ -' I 

Amount Due: $ __ __ 

L-____________________ ~, 

ILl ________________ ~ 

QSJ Inert Cleared for Intended Use 0 Uncleared Inert in Product 

Reviewer: 4i./t:N &~k",l Date: t/J':;' )// / / Remarks: 
34

March 22, 2011 

To Whom It May Concern: 

RE: Letter of Authorization 

Dear Sir or Madam: 

~nvmclo 

200 Cascade Poin1e Lane, Suite 101 

Cary. North Carolina 27513 

919-610-1065 

www.envincio.com 

", ; 

Please let this letter serve to confmn that Janelle Kay and Michael Kellogg of Pyxis Regulatory 

Consulting, Inc. are authorized to act as agent for Envincio LLC (EPA Company Number 87276), before 

the U.S. Envirorunental Protection Agency, California Department of Pesticide Regulation Pesticide 

Registration Branch and other state governmental agencies in all matters regarding our pesticide 

registrations pursuant to the Federal Insecticide, Fungicide and Rodenticide Act (''FIFRA''), 7 U.S.C. § 

136 et seq. and state law. 

If you have any questions, please do not hesitate to contact me. 

Sincerely, 

Randall V. Canady 

Chief Operating Officer 

cc: Pyxis Regulatory Consulting, Inc. 
35

Form approved. OMB No. 2070-0060, 2070-0057, 2070-Ot07, 2070-0122, 2070-0164. 

&EPA 

United States 

Environmental Protection Agency 

Washington, DC 20460 

Formulator's Exemption Statement 

(40 CFR 152,85) 

Applicant's Name and Address EPA File Symbol/Registration Number 

Envincio LLC 87276-7 

200 Cascade Pointe Lane, Suite 101 Product Name 

Cary, NC 27513 Equil S-Methoprene 1.2% IGR Concentrate " 

Date of Confidential Statement of Formula (EPA Fonn 8510--4) 

04/20/2011 

As an autholized representatTve of the applicant for registration of the product identified above, I certify that: 

(1) This product contains the following active ingredient(s): 

S~ Methoprene 

';' ) 

, 0 

), ) 

(2) Of Ihese. each active ingredient listed in paragraph (4) is present sotely as the result of the use of that active ingredient in the manufacturing, 

formulation or repackaging another product which contains that active ingredient which is registered under FIFRA Section 3 ~is pJrchased by 

us from another person and meets the requirements of 40 CFR section 1S8.S0(e)(2) or (3). ')' , 

, , • 0 • 

(3) Indicate by checking (A) or (B) below which paragraph applies: 0 0 

0 , , , 

01 (A) A, ,,,",,,, C,"","Ii,' S""m,"' 01 F"m"" (EPA FORM 8570-4) r" Ih' ,b", id'"'''' 'co,"" i, ,tt""" to Ih'; '''I;'~'"t ' 0 : : f "." , That formula statement indicates, by company name, registration number. and product name, the source of the active ing{edient(s} listed in" ; > 

paragraph (t). ' ., >, 

OR 0 0 

0 " " " 

, (B) The Confidential Statement of Formuta (CSF}(EPA Form 8570-4) referenced above and on file with the EPA is cowp:S~e: current, an , accurate and contains the information required on the current CSF. 

(4) The tollowing active ingredients in this product qualify for the formulator's exemption. 

Source 

Active Ingredient Product Name Registration Number 

S~Methoprene 

, • Signature 

~ Name and Title Date 

Ross Gilbert / Agent " 't/';l-o /d-ol I 

EPA Form 8570-2 Rev, 06-2004 Co py 1 EPA 

Copy 2 - Applicant copy 

*Product ingredient source information may be entitled to confidential treatment*
ct ingredient source information may be entitled to confidential treatment*
38

PYXIS REGULATORY CONSULTING, INC. 

4110 136m St. NW 

Gig Harbor, WA 98332 

COURIER DELIVERY 

Linda Hollis (PM 91) 

Document Processing Desk (AMEND) 

Office of Pesticide Programs (7504P) 

U.S. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 S. Crystal Drive 

Arlington, VA 22202-4501 

Apri120,2011 

Phone: 253~853· 7369 

Fax: 253-853-5516 

www.PyxisRC.com 

.,' , 

RE; Envincio LLC - Equil S-Methoprene 1.2% IGR Concentrate (EPA Reg. No. 87276-7) 

Amendment to the Confidential Statement of Formula (CSF) , " " . ; 

Dear Ms. Hollis, 

On behalf of Envincio LLC we are submitting a non-PRIA fast track amendment to revise Alternate 

Confidential Statements of Formula (no.'s 1,2 and 3) to the Equil S-Methoprene 1.2% IGR Concentrate 

registration. The enclosed Alternate esP's 1~3 are intended to REPLACE the currently approved 

Alternate CSF's I ~3. Envincio LLC is proposing to add new (but similar in function) inert ingredients. 

Neither the nominal concentration of the active ingredient or the nominal inert ingredient total has 

changed. Envincio LLC believes the revisions do not invalidate product~specific data for this product, 

and no changes to the product's labeling are required. 

The following documents are submitted in support of this amendment: 

1. Application for Amendment (EPA Fonn 8570~ I) 

2. Two (2) copies of the proposed CSF's (Alternate Fonnulation 1~3 dated April 20, 2011) 

3. Fonnulators Exemption Statement (EPA Form 8570-27) 

4. MSDS' for the inert ingredients 

5. Letter of Authorization 

As no data are being submitted with this amendment, nor will data need to be reviewed to approve the 

proposed amendment, Envincio LLC believes this action qualifies as a Fast Track amendment and is not 

subject to a Pesticide Registration Service Fee. 

We trust you will find this application complete. Please contact me by email (Ross@PyxisRC.com) or by 

phone (253) 853~7369 if you have any questions or need any additional information. 

Sincerely, 

Ross Gilbert 

Enclosures 
39

BPPD ForlJlUlation Amendment Check List 

Fast Track rn-and PRIA Actions B680 0, B681 D,B730D 

RAL: fv1. 

Form (EPA Form 8570~1) - signed & complete 

Call them 

2. Final printed IFNO,STOP! 

3. storage data)? 

If so have the terms/conditions been met? ~ 

4. of Formula (CSF) EPA Form 8570-4 Basic Formula D Alternate 

IF 

e, ! limits agree with CFR 158.175? Note if preliminary or 5 batch analysis 

f. 

g. 

h. 

from Section 1 limits based on batch analysis would need to be proposed under Section 

i.e., cfulgram)? 

on actives & inerts 

that have food or feed uses? 

CFR 1 codes 

i. Alternate formula(s) do not require different from basic CSF or other alternate CSFs. 

D 

j. pesticide? (When a or new basic 

new registered manufacturing-use product as the active ingredient source it must be detennined 

II~~~~~~~~~~~~~ products llsed to fonnulate are similar enough to warrant use of 

I k. peanuts, tree nuts, ,eggs i putrescent eggs), fish, crustacea, 

or wheat commodities? If YES, RAL must evaluate label directions for compliance with 40 CFR 

5. 

a. a) Using Selective Method? [[IF NO, SKIP to item 5 and note that data matrix should be used 

for the cite-all method to indicate the companies to whom offers of compensation were 

b. Data Matrix. Minimum Data Matrix for registration includes; acute 
40

d. Registered source used for active ingredient? IF YES, SKIP to ITEM 5. (Active ingredient is 

from a registered source and generic data should be satisfied by registered source. IF NO, generic 

data needed. 

e. Data passed PR Notice 86~5 for formatting and MRID number assignment? 

f. Public copy of Data Matrix provided? (PRN 98-5) 

6. Certification with Respect to Citation of Data (EPA Fonn 8570-34): See 40 CFR 152.80-98 

and PR Notice 98-5 [Note: Ifno data are required or submitted, a Certifjton with Respecl10 Citation of 

Data form is not needed. This is often true for minor amendments.] rJ W 

a. Did applicant check a Method of Support? 

b. General Offer to Pay checked for Cite-all Method or Cite-a!! under Selective Method? 

c. Is the form signed and dated? 

d. Check form and Data Matrix; are Exclusive Use data cited from other sources? . 

IF YES, is the required authorization letter included in application? 

NAO 

7. Formulators Exemption (EPA Form 5870-27) v;r::....J 

a. If registrant is using a registered source active ingredient in the formulation, is form filled out 

completely and signed? ~ 

NA 0 :;J 

8. Science Review completed? Comments: 

~AcW- ":::J\n ~\.ct c;. ~ 

inlernal BPPD Guidance Documenl - Oiher Items May be Required 2 January 20iO 
41

DATA PACKAGE BEAN SHEET 

Date: 27~Apr~2011 

Page 1 of t 

* * * Registration Information * * * 

Registration: 87276-7 - EQUIL S-METHOPRENE 1.2% IGR CONCENTRATE 

Company: 87276 - EN,V~IN~C~IO,,-"L,LC,,-________________ _ 

Risk Manager: RM 91 -_Andrew Bryceland - (703) 305-6928 Room# PYt S-891 t ___ _ 

Risk Manager Reviewer: ~enyon ~dams MADAMSO~ _______________ _ 

Sent Dale: __ _ Calculated Due Date: 20-Jul-20t1 

Type of Registration: Product Registration - Section 3 

Decision #: 448218 

DP #: (389168) 

NON PRIA 

Parent DP #: 

Submission #: 894333 

Edited Due Oate: 

Action Desc: (345) F~~MULA CHANGE;"!"ECHNICAL; 

Ingredients: t05402.'.....~:Methoprene{1.2'yo"-) __ ---------------

.-----------

* * * Data Package Information * * * 

Expedite: 0 Yes. No Date Sent: 27-Apr-2011 Due Back: 

DP Ingredienl: 105402, S-Melhopren,o''--_______ _ 

DP Title: ------------~-----

CSF Included: • Yes 0 No Label Included: • Yes 0 No Parent DP#: 

Date In Date Out 

Organization: BPPE~~ __ . __________ . 27-Apr·201 t Last Possible Science Due Date: 05-Jun+201 t 

Team Name: RM 91 27-Apr-20t1 Science Due Oate: 

R N j-,,";,\,>-" eviewer ame:~~~,R-m;se~ •. _._. ________ 27-Apr-2~2.1 __ Sub Data Package Due Date: ________ _ 

Contractor Name: 

* * * Studies Sent for Review * * * 

No Studies 

* * * Additional Data Package for this Decision * * * 

No Additional Data Packages 

* * * Data Package Instructions * * * 

Russ, 

Please conduct a CSF review. The registrant wants to replace Ihe current_rgp.P-S~9.f.Jt CSF # 1-3 enclosed. 

registrant is proposing to add new (but similar in function) inert ingredients _:. 

Th, 

Thanks 
42

PYXIS REGULATORY CONSULTING, INC. 

4110 136!h St. NW 

Gig Harbor, WA 98332 

COURIER DELIVERY 

Linda Hollis (PM 91) 

Document Processing Desk (AMEND) 

Office of Pesticide Programs (7504P) 

U.S. Environmental Protecfion Agency 

Room S-4900, One Potomac Yard 

2777 S. Crystal Drive 

Arlington, V A 22202-450 I 

April 20, 2011 

Phone: 253·853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

RE: Envincio LLC - Equil S-Methoprene 1.2% IGR Concentrate (EPA Reg. No. 87276-7) 

Amendment to the Confidential Statement ofFonnula (CSF) 

Dear Ms. Hollis, 

On behalf of Envincio LLC we are submitting a non-PRIA fast track amendment to revise Alternate 

Confidential Statements of Formula (no.'s I, 2 and 3) to the Equil S-Methoprene 1.2% IGR Concentrate 

registration. The enclosed Alternate CSF's 1-3 are intended to REPLACE the currently approved 

Alternate CSF's 1-3. Envincio LLC is proposing to add new (but similar in function) inert ingredients. 

Neither the nominal concentration of the active ingredient or the nominal inert ingredient total has 

changed. Envincio LLC believes the revisions do not invalidate product-specific data for this product, 

and no changes to the product's labeling are required. 

The following documents are submitted in support of this amendment 

I. Application for Amendment (EPA Form 8570-1) 

2. Two (2) copies of the proposed CSF's (Alternate Formulation 1-3 dated April 20,20 II) 

3. Formulators Exemption Statement (EPA Form 8570-27) 

4. MSDS' for the inert ingredients 

5. Letter of Authorization 

As no data are being submitted with this amendment, nor will data need to be reviewed to approve the 

proposed amendment, Envincio LLC believes this action qualifies as a Fast Track amendment and is not 

subject to a Pesticide Registration Service Fee. 

We trust you will find this application complete. Please contact me by email (Ross@PyxisRC.com) or by 

phone (253) 853-7369 if you have any questions or need any additional information. 

Sincerely, 

Ross Gilbert 

Enclosures 
Pages 43-44-*Product ingredient source information may be entitled to co
45

;-,: 

Decembcr 3, 2009 

To Whom It May Cllncem: 

RE: Leiter of Authoriza.tion 

Dcar Sir or Madam: 

Envillcio LLC 

200 Cascade Pointe Lane. Suite 101 

Cary, North Carolina 27513 

919-610-1065 

919-677-6161 (Fax) 

Please Ict this letter serve to confirm that Pyxis Regulatory Consulting, Inc. is authorized to act as agents 

for l:nvi11cio LLC (l~PA Company Nwnber rpendingj), beforc the U.S. Environmental Protection Agcncy 

and state governmental agencies ill all matters regarding our pesticide registrations pursllant to thc FcdcI1l1 

Inscclicide, Fllngicide altd Rodenticide Act ("FIFRA"), 7 U.S.C. § 136 et seq. and statc la\\'. 

If yOll have any qllcstions. pleasc do not hesitate to contact me. 

Sincerely. 

~d::7 FOlmdcr & Chief Executive Officcr 

cc; Pyxis Regulatory Con~111ting, Inc. 
46

Please Read Alilnsiruclions Selole complellng this Form (form must be typed) Form Approved OMS No 2070 0044 Approval Expires I 31 95 . . . 

United States 

&EPA Environmental Protection Agency 

Office of Pesticide Programs !7505C) 

Washington, DC 2046()"0001 

Notice of Supplemental Distribution of a Registered Product 

Instructions 

After a registrant has obtained registration for the basic product, the registrant may then supplementally distribute his/her 

product. One form must be submitted for each distributor product and must be signed by the distributor involved. The basic 

registration number and the distributor company number must be shown. 

If a registrant has a potential distributor who does not have a company number assigned, she/he should have the distributor 

apply, on letterhead stationary, to the Registration Division to have a number assigned prior to submitting this form to the 

agency. 

This Notice of Supplemental Distribution must be submitted by the basic registrant. The completed form must have the 

concurrence and signature of both the registrant and the distributor. 

EPA Registration Number ot Product Dlstrlbulor Company NUmber -- ;' J.. ",. 87276·7 I/I! (,', J .. 53883 

! Note; Do not submit distributor product labels 

Name ot Regislered Product (baSi" product name accepled by EPA) Distributor Product Name 

EquU S-Methoprene 1.2% IGR Concentrate Meteor 

Name and Address ot Distributor (Type: include ZIP code) 

Control Solutions, Inc. 

5903 Genoa·Red 81uff 

Pasadena, TX 77505 

Read All Conditions Before Signfng 

1. The distributor product must have the same composition as the basic product. 

2. The distributor product must be manufactured and packaged by the same person who manufactures and packages 

the registered basic product. 

3. The labeling for the distributor product must bear the same claims as the basic product, provided, however, that 

specific claims may be deleted if by doing so, no other changes to the label are necessary. 

4. The product must remain in the manufacturer's unbroken container. 

S. The label must bear the EPA registration number of the basic product, followed by a hyphen and the distributor's 

company number. 

6. Distributor product labels must bear the name and address of the disllibutor qualified by such terms as "packed for ... ", 

"distributed by ... "; or "sold by ... " to show that the name is not that of the manufacturer. 

7. All conditions of the basic registration apply equally to distributor products. It is the responsibility of the basic 

registrant to see that all disllibutor labeling is kept in compliancs 'Nith requirements placed on the basic product. 

Distributor 

We intend 10 market our producl under the Dlstrlbllor Product Name specified above, subject to Ihe conditions specified on Ihls Nollce. ,.' ' 

. ~e1~ 

.. , Date 

Director, Reg. Affairs 6/16(2011 , , 

, 

'...--- Registrant , 

, , 

, '" I agree tllat Ille disl~ r named above may dlsfribute and sail tile distributor Product specified above, subject 10 Ihe cond~t/ons specl:I'Ir!, ';f',II.liS Notfce. ' 

s~~~re!ft Ti e tr Date //IlL ' , , :f 

/ /[f'" ('-1: it. . '" , 'W,.,","," EPA Form 8S70.5 Rev. 8·94 Prevlou£'edilions are obsolete. White - EPA 

·u.s. GPO: 1988·432·472161004 

" , , 

, , 

, , 
47

Material to be added to an e-Jacket/Jacket 

R ego N O. Zl~7G-1 

1. ¢ Placement within the e-Jacket/jacket: 

o Default: (chronological, top/newest) 

o Description: (PDF page number, i.e., "before page 

45") 

2. 'lZl Send to Data Extraction contractors this material: 

o Newly stamped accepted label 

o Notification 

o NewCSF 

¢ Other: ~-"'J-f2w L.J.,L 

3. Attach this coversheet to the top of the material or jacket. It 

must be well organized and clipped together, NOT STAPLED. 

Then give the material with this coversheet to staff in the 

Information Services Center (Room S-4900). 

Reviewer's name: Sylvester George 

Phone: 603-0688 Division: BPPD 

Created January 26, 2009 

(}J,u\ i~ brQ,'::-
48
49

PYXIS REGULATORY CONSULTING, INC. 

4110 136th St. NW 

Gig Harbor, WA 98332 

Phone: 253-853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

COURIER DELIVERY 

Linda Hollis (PM 91) 

Document Processing Desk (FNL LBL) 

Office of Pesticide Programs (7504P) 

u.s. Environmental Protection Agency 

Room 8-4900, One Potomac Yard 

2777 S. Crystal Drive 

Arlington, VA 22202 

June 23, 2011 

RE: Envincio LLC - Equil S-Methoprene 1.2% IGR Concentrate (EPA Reg. No. 87276-7) 

Submission of Final Printed Label per the Agency letter dated February 15, 20 II 

Dear Ms. Hollis, 

On behalf of Envincio LLC please find the enclosed final printed label per the Agency letter dated 

February 15, 20 II. 

In support of this submission please find the following 

I. Completed Application for Registration (EPA Fonn 8570-1) 

2. Three (3) copies of the Equil S-Methoprene 1.2% lOR Concentrate final printed label 

3. Letter of Authorization 

Please feel free to call me if you have any questions or need any additional infonnation. 

;;;)J~ 

Michael Kellogg 

Enclosures 

, 0 , , , , 

, 

" , " 

" " 

, , , , 

, . , , , 

" , , , 

," , 
50

w. , ~ 

) ,_. o. OM" No, _,,. ,0," 

United Statlls Registration OPP Identifior Numbor 

&EPA - Environmental Protection Agency 

Z 

Amendment 

Weshington, DC 20460 Other 

i for ' . I 

• Compeny!Prod\Jct Number 2. EPA Product MenDger 3. Proposed Classification 

87276-7 L, Hollis o Nona o Rostrictod 

4. Compeny!Product (Nllmo) PM. 

EnYincio LLC I EqU-iI S-Methoprane 1.2% IGR Concentrate 91 

5. Nama lind Addross of Applicant (Includll ZIP Codo! 6. Expedited Reveiw. In accordance with FIFAA Section 3(c){3) 

Envincio LLC {bHij. my product is similar or identical in composition and labeling 

c/o Pyxis Regulatory Consulting, Inc. to: 

41 ~ ~~:6th St. NW EPA Reg. No. 

GiQ 0 ~A 98332 

Check ff (his is 1# noW sddros$ Product Name 

, • II 

D Amondment - Expillin bolow. ~ Final printed labals in repsonslI to 2/15/2011 Agoncy letter dOt9d o Resubmis8ion in response to Agoncy lettar dated D ~MII Too· Application. I 0 Notitlcetion - Explain billow. D Othor - Explain balow. 

Usa odditionol pagols) jf nocossary. tFor soction I and Section II.) 

Submission of final printed labeling for Equil S-Methoprene 1.2% IGR Concentrate per the Agency leller daled February 15, 2011. 

Section· III 

I t, " Thl, P';d;~';" d'~ 

Child-Resistant Psckoging Unit Packaging ~lIr Solutlle Packaging 2. Typa of ContoinOf 

[2jY" ~ Yas h Yas r;J Mol" .( No r.r No [{ No 

./ Plastic 

Gloss 

• Certification must If "Yos~ No. per If "YIIS" No. pDr Papor 

bo submitted Unjt Packaging wgt. container Packago wgt container Othor I 

1 oz:. to I a.- Locution of Not 

1.(1 

14, S{"", R."" 15[;8'.; ~,:~b" I r.f! Lobol , 10 x 1 fl. oz.and 16fl. 0', 

Is. Manner in Which Lobel Is Affb:ad to Product 

J , o Other 

Section· IV 

1. Contllct Point -;;;;~ o b. "hIs 

Name TItle Tolephone No. !1~cl~dQ Araa Codel 

Michael Kellogg Agent , I pc, , , 

Certification , 6. OeJJ ~pplicetion ,,, , ~ , . I certify thot the statements I heve made on this form end oft otlechmonts thOfOto afa truo, occureto and complo\i'. , Re<:eivoki 

lacknowladgo that eny knowlingUy fols9 or misleading statement may be punishable by fina or imprisonment or .ISiorn'Ped) both undar applicablalaw. " ' 

':''"=22 3, TItio , 

~ " , ' , Agent , ~ , , , " 

'YP Namo 5.0ate 

Michael Kellogg G/ ::2(f II / 

EPA Fo'm mO,t ,.", 3,94, s editions era , Wh., • EPA ... C"", V,'ow, 
51

Proof Approval 

If you have any questions, please contact 

ART DEPARTMENT 

PHONE: 406.863.3800 

FAX' 406 862.3544 

DATE. I~TTEN'T10N 

05/19/11 IRandy Canady 

LABEL DESCRIPTION 

Total Label USA,,, 

You, Toral Label Solution 

I~OMPI\NV 

I Envincio LLC 

Equil S-Methoprene 1.2% 16 oz./1 Pint Front ILABELs/zE 14" x 2.75" 

Front 

Please email mtwo,k to: 

art@totallabel.com 

500 Label Lane 

Whitefish, MT 59937 

DI~SHl\pE lOST 

RCR 

COLORS 

7427 Red, Black IUPCNUM8ER REWIND 

3 

LABELS/CORE 

12" 0.0. 

FlNtSH 

Lamination I~TOCK 

I White Bopp IADHESIVE 

I Permanent 

I 

Please examine carefully the intormation on this Proal Appro""l, The content and accuracy 01 this information IS your responsibility. Your labels Will"I 4t llIJ! It/ be printed exactly as you specify On thiS Proof Approval. Please verify and sign this Proof Approval. No production will begin without signed approval. (j I I, Ii 

• 

I APPROVED AS IS I CHANGES 

Signature of Authonzed Customer Representative Date 

,"'" "',. "" ... ' '"'''~.... "'''' "'"~ 

Equl S-M<tllopr,'lO t.~':IIGR c.ncootral. ~ notmamn.cture<!", Nl(tUieli 

(JyW~mOl1<'~'''''I''''~ orZoe<on, ,.tiM 011'riW'. 

£l'AR,..N .. aWG-7 

£fA Elt No. Iodfut,d by las! ~\tOf 

ot 1M b.!<;h ,umbOI' on thi> ~"ka~. 

IAl: 055-GA0001; IBI ~ ~3&I3-P:·002 

N'IColI\,nts:t Pint 

lronuflctl!'<d \01 

50t c.s"",. Pfitll' u.n~ -~ Surt> tOO t.ry.lrc~7513 

REWfND#3 

Signature ot Authorized Customer Representative Date 

Complies with 

EPA Accepted Labeling 

Date:_--l'-IF£:.tlB'-.II,..,S""Z ... OI ... 1 __ 

,', , 

", , 

• 

, . 

Gi',..<", 

Arii,t 00000 

Pmote·OOOOO 133420 073851 Color proofs are not Irue representatioll!i OJ color. 

Job Number Use for color breaks only. 
52

Proof Approval 

If you have arty questions, please contact ~- Booklet 

Please email altwolk to: 

ART DEPARTMENT 

PHONE: 406.863.3800 

FAX' 406,862.3544 

Total Label USA,," art@totallabel.com 

500 Label Larr8 

YO"' Total Lobel SOI"1100 Whitefish, MT 59937 

OATE I~TTENTION 

05/19/11 I Randy Canady I~OMPANY I Envincio LLC 

LA8EL OESCfllPlKlN 

Equil S-Methoprene 12% 16 oz. / 1 Pint Book 

COLORS 

Black 

FINISH 

Lamination I~OCK 

I White Bopp 

I LAflEL SIZE 

14" x 2.75" 

I~OKESIVE 

I Permanent 

OIESKAPE 

RCR 

REWIND 

4 

I Please examine caretully the imormalion on this ProOI Approval. The conlsnl and accuracy ot this inlOrmtllion is your responsibility. Your I~twls will I 

be printed exactly as you specify on this Proal ApPl0val, Please verify and sign this Proal Approval. No production will begin without signed approva!.! 

I APPROVED AS IS ICHANGES 

IABELSfCORE 

12"0.D. 

lid/itt (i t 'fM; 

REWIND #4 

Signature ot Authoozect Customer Representative Signature ot Authotlled Custcmo:.- Represenlalive Date 

II!qui/~ 

S-Methoprene 1.2% 

To Prevent the Development of 

Adult Fleas lOT Up To Seven MGflths 

AC11VE I~GREOlmT' 

(S1-MOIh<)j>renoICAS #65733·1 6·6) ". 

onlER INGREOIENTS':., ,.~ 

'Conl,ins pelrQ10um d~~Ir.I" 

EIlu, S-MelhOiJ",n" 11% 16R Co"'.nt",,, ~ '"" manu1:lOlurod ., diatnbolOO 1>'1 w,llmarl: Int" .. I""',1 " <00001\, setler, oIP,oeo,e. 

KEEP OUT OF REACH OF CHILDREN 

CAUTION So< 10,1 .. labeillooktel "" fiRST A10, 

I'fIECAllTIONAllY STAl1'MEmS ond OIRECTIONS fOR 

lISE Inci(Jdlng STORAGE ANO OISPOSAI. 1 .. ""oIion .. 

_nvmclo 

El'AIIo,.No.mU-T M"'E~~~~:l~ El'A Est. !Itl.lnillcated by\a.llottw 501 Casc.del'oinlO i1lne. 

Ollhe b;l\Cll numbe' .... l1li. paok,!I". Suil. 100 

IAI ~ i)5;'GA-OOt; til): 5J88:l-TX-002 C;o'Y. ~C 11513 

Ani" 00000 

Pcootet 0 0 0 0 0 133421 073851 

Job Number 

" 

, 

, 

, 

, , 

, 

, 

. O. nol g;" "~Ing b1 

fa, CI1otniool Spl~, loa!<, fire,., f;:pow". 

c.Jl: CHEMTIIEC 1-8IJO-<I24-9300 

for Modlcal Emtfll""" .. llIlty. Call: _267_411 i 

PRECAunDNARY STATEMENTS 

HAZAllDSTD HUMANS AND OOMESTlC ANIMALS 

CAUTION Harmful il _eel lhrnIlijh the Sl<ifl. Cou ... mod"",,,, eyo 

Irrilatlon. "'01<1 <onlaOi with Skil\, eyes. ., c1olfling. WaSh 

tfloroughln.rl\h """" and water afWMnttllf!1l, ' , , , , , 

., , 

Color proofs are not true representatjol~&" at color. 

Use for eoloT breaks only. 
53

9/11 

I APPROVED AS IS 

Signalure ot Authorized Customer Ropresentativa 

DIRECTIONS FOR USE !I i,. uio!alion 01 Federal Law 10 u,OIN. ~ro~OCI" a mann .. 

inoonsislen! with its lab.lini, 

Thi' ~"~UCI mal not be uWl 0' ,ele .. nce~ as, ""u," 01 

;'i"tP.Onl ill Iho to,mu!alion, manulacture, 0' regill"'on 01 

"'" 01l10, ~"OUCI$ will10ul prio, w,iuen .utho,I,a\lon lrom El1u.,oioLLC, 

PRODUCT INFORMATION T~is pf\l~UOI contlln, Ih •• c~u. Ing, .. !.m S.M.thopO'eno, 

,., insect ~rawtl1 .. ~ublo' I~'I pro"nl' Roo, lram maturin~ 

inlO adu!to b, .cling In th' •• ~, m"!)O, 01 development. 

Tre,lme"1 willl Illi. ~ro~oc! on ."., w~"e tho" at. II", 

!","e, th~1 Re. !o",". will en!" into, 0' wh." R.a og~, M"O 

be", do~,,"il'~ w!! ~"Uonl ,~u~ R.a, lram ~,u.lo~i lor 

IIjl 10 7 months, Becau" I~i, 1IfO,,"0I1 •• ,,",wlh ,egulato" 

i! does nOI affect R, .. that 11 ... , ... eII,d lui! ~.u'lo~m.nl 0' 

n"s th.1 h.\fC ,e"""oo th. pu~ •• ,tag" 

!MPORTANT N~TE: !n o,~" 10 p",u,nl tie .. trom b.lng 

inuo~uoo~ "~oors, ~ 0; impcrt.,,1 10 ueal p.ta 10 CI1.". I~'I 

Ih., tIo not c."y flea,. Treat ~eto with a product "gi.I".~ 

w~~ I~. E~A""~ !,b.lo~ lor sum. use. 

M!X!NG O!AE(;lI~HS 

~,ep"e lIfO~uct ... a dilutad $pray ",IIllion b, ao~in~ to,"",. 

01 I~~ ~ro,,"ct to 112 ij'liion olwate, in. m!'",g COOla!n .. .,,~ 

a\lllalO tho"ugll!j'. ThOll od~ an Mdittonol 112 !/O!too 01 wOle, 

an<togtlalo ogain. ",,!Ung in one g;l1!on o! lpray solution. 

STORAGE AND DISPOSAL 00 not Oootaminoi, water. tood. or Ie,," by s~ on~ 

~i,posal, 

PEST!C!OE STOMGE: SI"", in a coo! ~laoo ""'" trom ho.1 0' 

0jl0il flam .. 

PEST!C!1)f OISf'OSAL.: Wn.stes I1)Wtti"ll from 1"" ""0 ot 1111, 

lI<ll~uol may b. d~ ot on sit, 0' oi on aPI''''''''" """,I. Oiep_!fao~rty. 

COIIT.lIhElIIlANOWIG: N<>n/cfiltah!e Cllnbiller, Ito not ,,_ 

0' ,efiI! lI1is """tai"",. Tripi, ,ill" container lor o(!IJil'Olerl~ 

II<llm~il1 alIer ."",tyll1g. Trip!' 'in .... tollows: ,m~ty jj,. 

rem.inill9 corn,1l\:! !"'" 'Pllllca~on .quiJlment 0< 0 mix I>i1k 

aM drain to, Ib .<co,,"' .her I~, Row hegins 10 drill, f~! Ill' 

oQ<ltaina, 114 M wWl w.ter and ,.oap, S~ak1! tor 10SllCQll</o. 

Pour ,.,,,,Ie into ""pllcatlOf1 .quijlm.nt or b ma tank er ito" 

liMate lor lale, use 0' ~i'~I. bra!n!or Ib ,,,,,"oos ,l!ertho 

IIow b<gin$ III <fri~ RO~'"1 Ill" procedure 1M> mo<e ~me" 

Thon off" lor ,0000olin~ II .... loIllo 0' ~""CIIJ" aM ~iopase ot 

in • '''itar, """fi!l, 0' by .,o~erat;"'. or, II a!lowed by $tal<! 

""~ fa",,! ,ulllorltieo. tim" ~ bum.~, oul of ,""ox~ 

CONDITION OF SAlE ANO UMITATION OF 

WARRANTY AND UABIUTY IIOTlCE: R.,," IIle Mti'eOireo!iQf1,Io,u •• ""g OonOi~Of1' otSoIe 

an~ limftotion ot wa .... ty on~ UaIJ;lity before bU)'ing 0' usll1g 

jj,"PrOd\lCL ~111' term ..... not otttpt\l)ie,ll)\\Jm tho producl.1 

Q<loe,lIIlopena<l."~ tho purd1,.0 prloo wi!bo reflIlltted. 

Tho biMotioos !or Use of til;' Product must be fa!lowed c","fully, 

~ Is !mpoosfblo 10 elimillal' .I! nol<, !nhe""'il1."""'i"",~ w<th 

tho .... 01 111;; product. In,!!,CIiW1, .. or Olll" unlnlfllldod 

co .. oq""oc •• m.y ",,"II he"..... of ,udl tacter:s as m ....... o! 

""e or ""~IOtat>o,,, W"II,,~ pres"",e of otIlor malollol' or""'" imill'flCi"ll toctors In til. ",a o! 1M 1I<ll<loet. whict1 or, boyer1g 

jj,e comrot of El1Uil1.io I.l.C or S.1!e~ To the I)X!ooI CO"';SIIlm 

with ,pplicatJl' !.", .11 ooch fisk; shlil he a",",,",~ by Bu"" ..,~ 

, 

Your label~ will be printed 

I CHANGES 

SignatlJla of AI.'lho~zed CUstomer Represantallve 

TA~KM!XES 

~ the,. i, oIrea~, • hi!Jh ~O~!'lion 01 Rea, .1 the Ming 

l.du~l.tag., I"'~'mi:< thl. ~roOuol with an EPA regO;tore~ 

pro~uol I~'I i, !olJ.I,~ to, uso 10 oonlroltlJ!fy ""uelo~ecll.~u~ 

R,as, M~lh. broduol)lOlJ M. I>!l~ ml,;n~ wi:!! this p,od"OI 

to liZ 9'I110n 01 w.ler in ",. mi'ing Clln!lline, an~ a~il.lo 

I~O(OlJ~~fy, TIl.n a~~th!' ~'o~uOI 10 1M mi:<in~ Cllnlainer M~ 

,~il'l' IurUm, flnal!y, a~~ an id~iliM'! liZ gal!Q<l 01 w.IO, 

10 tM mi.in9 conl.iner to creal. one g.!!on of ,~"y solution 

ond "!Iitol.lII. mixture lil""'ug~ly, 

APPL!CATIbN RATE 

Ap~fy thO; pro,,"C! .1 tho ,alo 01 t g.!lon "'Med "%I' 

solution"",, "MIXING O!RECT!O~S' aboW! ~er 1>00 'quare 

!oel 01 surl"," ,,,a. 

MUH~O Ilf APPlICAT!ON 

In o,do, to pO'ou,nl n .. , ..,d ~ .. inl"talion, o~ply th;, 

praduOI beto,e thl lie" sea,oo. U,""'"~p!I,"lors mu,1 

ono"e I~'I Ih.y ,~al<e the solution well plio, to o.c~ uso, 

Ap~!, 10 .reas whore Ilea" lie. e~ge. an~ t!e~ !arval er'" 

.... !I~'!' to be !o"led suoh as SUrlaoe$ wMre vets ,!'OV, 

OO'l"!'. '"~, ""~ upl\O!store~ lurn~ .... tinclu~inb on .n~ 

""do, "",ilion, .n~ I~"W ,"g'l u,lng a !ow pressure s~"'YC' 

With. ton lill IW.C'!fy u,.~ lor ~dOOf .~~liCtlllenS, 

NOTE: TIl .. pro~utt Iyploally w!l! nol sl.in m.to,I.!, thot 

would MI bo ,tain.~ b, I'I3ler alone. How ... " ~,!or 10 lu!! 

aW!ioation a lesl sI\oul~ b, ma"" b,ab~!ylng a sma!! amount 

of tIi!ule~ so!ulion 10 an i""ons~ou01J' ..... !n oro", to dot.""in. whetherilatninb ",!II ta~, ~!"" •. 

/IIIoi~ contaol with ....... I~al have been tre.led u"li! I~OY 

~ .. 

U'e<; and BUler and user agree to hol~ EIW~clo I.l.C an~ S.!~, 

harmless tor My 01>1 .... ruEaoog to suo~ !aotor<. 

OIMntiD I.l.C """",,\'l jj,.1 this producl Cllniorrn, to 1ft< chom;Cil 

d .. cription on ti10 Ia/le! an~ ~ .. ..,,""'iy rtt for Ill' ~Ul']JO'" 

state~ in tho OI,octiMs 1M lfuo, sulli~ to the irri1e .. nt fioI<, 

rulo",," to 'hove, when u<cd io acwrdonCll willi ~i,.,,;lloo, ..,~" 

normal use <C!l~i!iaFlS. TIlis w"'""ty doos IlI)\ extend to tho u" 

ot l1li, product <C!ltfilry to !i\b0! ""trool"",, 0' un~" ab!1orma! 

condi~on, or ""00r contlitions not roaoonal>ly t_.eatl. to or beyond !II(! Cllntn)l ot S(I]kir Of En~no" I.l.c. ..,~ BU)'O, arlO 

u,e, ",""m. tho rts~ 01 any SlJeII u"", To 1I1e e>;iOnl COIISlstem 

wlill appIicablo IiIw, ENVINCIO u.c MAKES IItl WAAMlmES OF 

MERC!/ANTABUlY Oft OF FITNESS fOlI A PAA11C\1lA1! PIIAP~S~ 

NOR Am OTHER EXPRESS OR IMflJED WARIIAIfIY E<CEPT AS 

Sl1\TEO/lJlOl'E. 

To th, ,<lonl con,istenl with a~pl""'b!. !.w Enulnoio I.l.C " 

Sollor Shal! nOI be !iob!. lor 'n, iIlo!~ental. Con'''lu.ntia! Of 

s~aClal o.mage' ,"SU!llng lrom tho us' or ~""d!iIlg 01 thl, 

~",,,"ct. To tho eXIoIll coo,i,lonl ",!jj, apblloap!' !.w, THE 

EXClUS!VE REMEtIY OF TIlE lISER OR BUTEA. ANI) THE 

EXCLUSIVE UA9!UTY OF EN'I!NC!O LLC ANO SELWI F~R 

AllY ArlO AU. CLA!MS. LOSru. !NJIIR!ES ~A ·"o.JJ,,),tfP ~NCLUbING CLA!MS SAS~O ON IiAEACH Of vI}lIlW'JY. 

COIITMOT, N,SL!GEIICE, TORT, S"m!CT L!A~:t!TY OR 

tfTHEIlW!SE) RESUlTlNI) fR~M TIlE USE OR Hl\NbUNG OF 

~:~~~~~;~~~Tn~~~~ ~~:g;o~~~~~~' LLC on SEtLER, THE REPLACEMENT OFTHE PRbOliCT. 

En"'o" u.c ""~ Soil" otter 111!, product. ""~ B~ p~ , lkw 1I<:<opt tt. subjecl 10 ",. to<egoln~ Condition, of 5>le ~nd 

LJm~.1iol1 01 Worr.>nty an~ liobifity, whid1 may not b. med'lied 

... opt b:I _ ogruemCl11 'igned b:I a ,,"Iy a~p,,,,,I,J 

'ap,esontati" O! ErtvinciolU:. 

~'''Of .n~ Zooo"" a", "~i'lere~ tra~e ... rks 01 Welim"" Inlom.ltooal. 

EPA2\lltlJ4!1 

Dala 
54

1.2%16 1 Pint 

" 

I APPROVED AS IS I CHANGES 

Signature ot Aulhorized CUSlomsr Representawe Date 

II!qui/ru 

S-Methoprene 1.2% 

TGR ConcenTrate 

To Preuent the Development ot 

Adult Fleas tor Up To Seven Months 

ACT!V£ !t«;IW)!ElU: 

!S1·Me!hol"1'"' ICAS mm-16-6) ."_ ... _., ........... 1.2% 

ornEll !t«;I\tO!UlTS', ............................ , .... " .. 98,8% 

TOTAl.: ." .......................... ," .. ".100,0% 

'Con!ains p,uo~um ~i'!I'a!" 

EQui! S-M'!~O\lrene 1.2% IGR CoII<.ntr31e ~ no! mamJlac!urW or ~i'tritlut(>d II)' W,IIm,r): !nt.ma!ico,1 or Z"""OO,Sel!,rsolprscor", 

KEEP DUT OF REACH DF CHI..DREN 

CAUTION s~~ lato! bookl,llor F!I!ST AlO. PRECAUTIONARY 

STAr£MEIfIS ."~ O!IItCTIONS FOIl USE !nokJl:I!"8 

STORAGE AIlO OISPOSAl. tn.lruc~o",. 

ti 

Signalure ot Authonzed Customer RepresenlatNe 

" , 

, ) , > 

, ' 

" ' 

,>, , 

Date 
55

Proof Approval 

I! you have any questions, please contact 

ART DEPARTMENT 

PHONE: 406.863.3800 

FAX' 406.862.3544 

OATE IATTENTION 

05/19/11 Randy Canady 

LABEL DESCRtPTION 

¢. 

Total Label USA"c 

You, Total Label Solution 

ICOMPANY 

I Envincio LLC 

Equil S-Methoprene 1.2% 16 oz./1 Pint Front 

COLORS 

7427 Red, Black 

~" lamination 1

=" White 80pp 

LABEL~ZE 

4" x 2.75" 

I

ADHESlVE 

Permanent 

Front 

Please email anwark to: 

art@totaliabel.com 

500 Label Lane 

Whitefish, MT 59937 

DtESHAPE 

RCR 

REVItNO LA6ELSICOAE 

3 12" 0.0. 

I Plea~e examine calefully the Information an this PIOO! ApplOval. The content and accuracy ot this Information is your responsibility. YoU/labels will I (l-/~ lit! 

be prlnted exactly as yov specify on this Proof Approval. Please verily and sign this Proal Apploval. No production will begin without signed approval. I /8 ",/,./; 

I APPROVED AS IS 

Signature of Authorized Customer Representative Date 

- -' "'" ." ,"" ..... "'''' "'~ 

M>t 00000 

Proofer 0 0 0 0 0 

'1'J.1I<g.~,,8727~·1 

EI'J.Eat I/o.lnlll .. to. 'It.,II,Ito, 

oIth. b,l<:h n.",lm ,n\hl, poclc.~. 

!At: ~.GII.-OIlt; (lit: $36113·rx·1lO2 

N,t Corrt,"I~ t Pint 

133420073851 

Job Number 

I CHANGES 

trf3. ... .,~~1¢r 

"W""lit 50r ca.oad. Poi.;!<I.rul<.Su!Io roo 

cary. tIC 215rJ 

REWtND#3 

Signature ot Authorized Customw RepresentatlVB Date 

, 0 , , 

Color proofs are not true representati?rJ~ ;:,f ::olor. 

Use for color oreaks only. 
56

Proof Approval 

I! you have any questions, please contact 

¢ Booklet 

Please email artwork to: 

ART DEPARTMENT 

PHONE: 406.863.3800 

FAX' 406.862.3544 

Total Label USA"" art@totallabel.com 

500 Label lane Your Toiol Lobel Solulion Whitefish, MT 59937 

OAT~ IATIElffiON 

05/19/11 I Randy Canady I.AS~l OESC~I!>TlON 

Equil S-Methoprene 1.2% 16 oz. / 1 Pint Book COlORS 

Black 

"~" Lamination I~TOCK 

I White Bopp 

ICOMPANY 

I Envincio LLC 

ILA6~lSIZE 

14" x 2.75" 

I~H~SlV~ 

I Permanent 

OlE SHAPE 

RCR 

REWINO 

4 l.AlI~LSICO~~ 12" 0.0. 

I Please ex~min& carefully the Informa~on on !his Proof Approval. The content and accuracy of thiS Information;5 your respon~jbjljty. You, labels will I //(/ //,1 

be printed exactly as you ~pecity on this Proof Approval. Please verify 3nd sign this Proof Approval. No production will begin without signed approval. I (j ~ -fix';; 

I APPROVED AS IS 

Signature of Authorized CustQm ... Representative 

... , "" ,,,,, 

~quil'" 

S-Methoprene 1.2% 

To Prevent the Development of 

Adult Fleas for Up To Seven Months 

ACTIVE ING~EO~: 

{S1·Methoprc"" {CAS r65733·! 6 ·GJ 

ornE/! tIW~EPlmTS' 

TOTAl: 

'Conbin, pe\lol,.m di'111,ms 

EelU" o·lIethOl're"" 1.2% ,"R eoU.ntr>I, is no! 

m,,"ufar:Med 0' ~i'tn".1ed ~1I'/etlm'" Inl'rn:II~nal or Ltw<o'" "I:",. 01 Prec",~. 

KEEP OUT OF REACH OF CHILDREN 

CAUTION 

Soot",fd. lab!! bOokl!lto, FIRSr AlO, 

PRECAIIII~NAAY 57ATEMENTS 'n~ Ot~ECTl~No FOR 

lISE Including STORAGE M~ ~IS!'PSAI. t""'II<Uon,. 

-nvmclo 

EPA ~'9. No. 8727 .. 7 Ma"~~~: ~o~ EPA Est.1tJ. lndl .. led byu.'ttctw SOl eaSOM. ~o~nc lal1" ot Ill. ,.tetl """,1m on this ,,",eka!/!,. S",1. !~l 

1A)~655-~t:{B)~5l3(1HX..(J02 tary,NC215t3 

.. '" .... -,"''' .,. 

Date 

Am,' 00000 

Peoofe. 00000 133421 073851 

Job Number 

REWIND #4 

I CHANGES 

Signature of Authorized Customer Rep<e~entatlve Date 

" 

,il ,. 

for CIltml .. 1 SpiH,l,>k, rore, ~,Expo$"IlI, 

C,II: CHEMTRa; r·00I).4z+9:IOO 

For Medical <mOl!/Of1c!e' OnfJl; C,II: 866--257·4118 

PRECAUTI[lNARY Sl1IT£MENTS 

HAZARDS TO HUMANS AND OOMESTIC ANIMALS 

CAUTION H'lT11fiJ1 I aboorllod throulih !he skm. ca .... mod<Jlat, eye illltatioo. AIIoid contac1 Mill ,~, ~ or ~IOlfling. IVa:lh 

1ll"0~lyw"",oopOlldwnt,,,.n.r"0IIdIi"ll_ , j J , , j 

, , 

" 

" 

Color proofs are not true repyesentatlc'ns,,,(c.'Olor. 

Use foy color IJreaks only, 
57

Proof Approval 

"'~ A-rrENTlO~ 

05/19/11 Randy Canady 

LABEL O~CRIPllO~ 

Equil S-Methoprene 1.2% 16 oz. 11 Pint Book 

COMPANY 

Envincio LLC 

COLORS 

Black 

JOBWMBER 

33421 07385 

Please examine carefu!ly Ihe informalion on lhis Proof Approval. The content and accul'llcy 01 this information is yOllr responsibilfty. Your laoo!s will 00 printed exaclly as 

you specify on this Proof Approvel. Please verify and sign this Proo( ApPIoYa!. No production will begin without signed approval. 

I APPROVED AS IS 

Signa lure of Aulhorized CuSlomer Representative 

OIRECTlONS FOR USE 

III, • ,'o'al'on olf,d.tall.w 10 ",. tl1t$ tmJduOI in a manner 

incons~I'"I wttlt Its labelil1ll, 

TIli' pro<flJcl may 1101 b,"sed or rel",cnoed as a 10"rtC 01 

ing"dlml",",P l"mu~lio", ma"ul.ot"re, or ,"gi,tnI~o" 01 

,n, o",or pro<flJ.t> willlo"I pfl" w,in.n a"lhO,illltiO" fmm 

""vll1cioUC. 

PRODUCT INFORMATION This IIMd"ct cont."" 1M a~ti'~ inorapieni $·M''''PlIMnt. 

an in .. ct oro"'" relllJlal" IMI prevenl, flea, from m.to'"'~ 

loto adull' by acting in 111~ .. rl, SlO~ 01 <Ie,,~pm.nl. 

Tm.lmenl wil" lIlis p,od".1 On are.1 wl1ere ttl" .... n .. 1'''''1 •• ll1al fl •• I.,,,. wi! .",lOr inl»,or whOf' lleo .i~' l1a,. 

b,,,,, d.p"oted will p',,"'nl adu~ flea, from d""c~pin~ 10' 

"PlO 7 mon111" B ... ",. Ihi, ptMuct Is, grr>wIIl rel"I.I". 

il do .. nol .H"I ft.a, 111.1 h.", reached fuI! d,vel<!lmenl " 

II ... Ihal h.,. read1.d Ih' pop •• ,"'oe. 

!MPORTANT NOTE: In o,d" 10 prev'nt II .. , from """'~ 

inlroO"COd ioOo"". ~ il Impoftoot 10 "".1 pelS II' e","re Ihal 

tho, <10 noloarry 11 ... , Jr •• 1 bol' w,th. produOI re~i'tored 

wjllllllC EPA and lab.red lor swell • us .. 

MIXING DIRECTIONS 

Prepare p,od"ct " • dllut.d ,pray ",hJIIM by 'ddin~ I OU"C. 

ollll;, prod"ct 10 112 gallon 01 w.IO,., a m;xinooonta"" anO 

agilote Itiorou!jltly. TIl"" .dd ." ad<l"~o".1 112 gallon 01 ""lor 

aop a'''Ie aOain, ,"S\JII~~ ., on. gal~n 01 'PI'"' SOlution. 

STORAGE AND DISPOSAL ::1 00 not en""""mate 1'101". lcod. 0' I •• d by ,"mgo an~ 

d~p">I, 

PESTlC10E STDIlAGE: SI ... m , enOl pllee aw.y lrom "".1 0' 

"1'''' flam .. 

PESllCIOE OI.POSAl: Wul" ",ullinO kom !he """ 01 Ill'" 

prOO<r<l "'., be di'po'oo 01 .. silO or al an appnWed was1p 

<lispwaf locmty. 

CbNTAlNEflIW/IIUNG: Non"r.lbbl. conl:l.iI18r. "" no1 'euse 

0' "Iii! ttli, """tam," Tripl' rinse 00111.11"" (or 'Q"ilIale"~ 

promplly aftar emplyi"!I- Tnpl. rinse ,,!Ollows, Empty tho 

"m.inmo ,." ... ts into ,ppli<otion oqujpmonl or • milr tank 

and ",.in fo, 10 ,econ<l"II" 111, flow bc~i", to POi!>. F,; 111. 

c""tal .. , 114 NIl witllw.lOr and ro<:$jl. 5I>a!<elor 10 ,orooO', 

Pou, ,",s:lIe Inlo lIjl~icO)ti"" '"l\Jipmonl 0' a mIX tanX or "or. 

"",al.lor ~I" ",. or !lisp05a[ omi" fur lO.oc""Os aft" "', 

IIow b'g;" to drip. Rep"I thil PlO¢<>d"" two mo" ~m ... 

111<11 off" lor rec,dll1~ ! ... i""l0 or pu"cture and ~.P 0::1 '~ • ,,,,Io,y laI1or,~ " by 'If1Ci""'tion, 0\ W albwod by ,tal' 

""~ loeal.u1Ilooill .. , bumin ! b"mod., out 01 ,moll'. 

CONOmON OF SAlE ANO LIMITATION OF 

WARRANTY ANO LIABILITY IIllTICE: R",d 111Ccut"" Olroclion, forlho ""d CMdiUQI11 ol Sale 

an< lim"","," ot Womwlty ""d Uabllity b,lo" buying Or usl"ll tl1;,product IIIIle to'IllS'" nolocceplobl,,"ltim ttl.productal 

once, lIIlop",od, OM tl1. punilO$C prico will b, re1IJnded, 

TIl' Oiroclio .. lor U,. 01 "'i, Prodt!d.RIlJ$I t.e 101",we<lCOIONlI" 

fl ~ IJllj)OO<ible 10 Olimll1.to ~1I11sk$I"hcrootfy ... oc~d wtlh 

me u" 01 UJj, p,""uet IneflOCl~'''so 0' othor """te",lcd 

COllSoquern: .. m.y mull "" .... ,' ol SlJch I,clo" as man"" 01 

u.s. or appncaoO", w .. 111". P""""" 01 othor maleri,1!! pr oth ... 

inlhJern:ing facie", in tho "'.01 Ih. Plod"", vdliCh .... Oe)'llnd 

tl1. c .. ~1 01 ErMncio UC "Sell ... , To ttlo """ot o"",is'",'" 

with appIi ... ble law, pll 0U<Il "",,,"<liin be ... "mod by Buyet and 

Dale 

I CHANGES 

Signatule o(Avihonzed CuslomS! Representalive 

TAHKMIXES 

!I ~.,,,. i, i!J"ad, , hi~h popol.Iion 01 II"s al "'. bili"g 

(a<lull) S"'ie, I'nk·mix thl. prOO"ct wlll1 ." EPA rogts"red 

product Ih.1 il tot.eIOdlorllSa 10 co"lrol lully d''''lop<clJadull 

lie .. , Add th' produol)lOlJ or, tank mi,",~ witl1 Ihj, p,o;l""I 

10 112 galon 01 waler", the mi,jn~ CP"!a~" .nd .gll.I. 

Iho'o"Ohly, loon .dd 111i, prod"cllo Ih. mixl"g ooot.'n., ond 

agital, lurthe', ftn~lIy. add "" addnjo"oj 112 gallon 01 w.I" 

10 Ill. ml""9 ~""Iai"er 10 orealO ""p gallo" 01 Sjl",y solutio" 

.nd 'ojtatt IIlC mixture thp,oughly. 

Al'PlICATlO~ RATE 

App~ tl1ts Pfoduct al Illc rale 01 I gallon dllUled Sjl",y 

.,I\lUan (,.e "MOONG OIi1ECTIONS· abo",) pe' l50b 'Qua,. 1"101 'urlac. " ... 

METltOD Of A1'PLICATION 

~ oro" to I"'."nl II ... ""d ft •• i"I.Slat;"n. app~ Ihi, 

oro1llJcl b,I". Ih, flea seasan, lISerol'pp!i<:alors musl 

enS"" Ihalln,y ,11."" Ih. ,01"Ilp" Well prior to e.eII ", .. 

Ai'ply 10 " .... Whe .. II • .,. II,. .ggs and Il,a to",. "'. 0' 

arc Ilkel, to bp 10"'I'd ,uch as ,"H.oes wIlo:<e pet> Sleep. 

O''lletl. "'~, and upllolm"d I"'n~ur. (i"cl"dino on and 

under c",hjO"S ond Il1I111'1 (\l0'1 ",jni a ~w pre,,",. ,p",er 

wllh a I.n ~P I,pio,'I, "IOd I" Iodoor 'pjllicollo",. 

NOTE: TIliS P'o<I!JCl typically wm nol mill mm,I.I, tl1M 

wo"'d nol b. ,tained b)' waler ."'n" However. Pljor 10 lull 

'pjlli."lo" a 1051 SOll"ld be m.<lplri .pplYlng • ,m.lI.mO"nl 

01 pol"tod ,01"Iio" 10 an inconspicuous or,. in 00)" 10 

d'Iermtne whelher ,tajning will lal<o p~o" 

A,pld O""Ioct With are .. Ih.I 11." "",n keatod "nlll Ihey 

are pry, 

lIw •• nO E",er and Usar ""roe 10 l1~d Ell'Imcio lLC..,d s,u., h"mioso lor any claims ro!i\IioO to ouCh facto"," 

"""""0 ILC warrnnts 111.1 "'" prOOuctcO)l1tC<mS '" It", Chem;cal Oe~~on on tl1. 1aIl,I and ~ " .. o .. illy Iillor 111e pUIjJ .... 

.... top i" ttl. Oimltans for U'~ 'tJIl~I " me inherenl n'''" 

"Ierred 10 obow. wIl," u.ed ~ .~(lr1i"'cewiill diract~"' ",,<lor 

normal ... coodlltans. TIl~ "",..-anI\' d ... npt I!xtend 10 !he"", 

of "'i, proil\lcl ",,"lIlIry Ip laIl,1 in,truCtionl. or under abll"mal 

COnditions 0' ""c1or """dioo", not "."nobly hlre<s00al>~ to 

or bey<lfld \he conlflll 01 S,II ... or En~oc~ ILC, and !I\J,,, and 

lmr &Sitlm~ lIle "o!< 01 .ny !Nch ..... To 1M ,>len! consistenl 

wilh awt~a\ll. law. EIMIlCIO UC IAAKES NO WARIWffiES Of M!:RCHANlABllIfY 01\ OF F!TllESS FOR A PARTICUlAR PURPOSE 

OOR AllY (J1IfEA EIO'IlESS 01\ IMPliEP WAAIWlTY EXcr~ AS 

STAlED ASOVE, 

To "' •• >:IMI oon,I''''nlwith apjll;cabl. law E"""cio UC" 

S,IIe, ,noll nol oe Itsbl. lor any incittenl'( enn"Q"'n!lal " 

Sjl.,'al dam'go, "",ullino lrom Ih'"'" "h .. dljng of tl1is 

product 10 111 •• xI1!nt o"",i,lOnl willl appli<oolp law. THE 

EKClUSIVE RIMEDY Of TIlE Usa! OR DUTEA, AAb TltE 

fl(ClUSIVE UABILITY OF EtlVlNCIO UC A~O SEiW! RJA 

/lIlY iUlb AU ClAIMS. LOSSES. ItlJlJIllES ~~ -lI.'J{.).CW 

(I~Cl UblNG CLAIMS 9ASED ON BRfACH OF 'WAAp.,\Im: 

~~=~:~ :~~~:~EfR~~R;'KE S~~CToo ~';~~~ ~: THIS PROOUCT, SHALL BE THI: REruM OF Tlt'l>F1I.CI:A.iE-' 

PRICE OF THE PROOUCT dR. AT THE ELEOTION OF EII~IIWIO' 

I lC bR SELLER, THE REPLACEMIIIT OF TltE PRODUCT. ' .' 

Elwlnda liC ."d SOli ... 0/1" "'is p!Q<flJct, ..,d BuylJr and 

U .. , accepl il ""biact 10 tho fc"!IOI"Il Condnians Jls.,-. ilna 

limitation 01 Warranty and liliJi'ty. wtIich ... , not b, m~iti.d , 

oxoopl by Wlllton <>greem'n! "!jI1ed by a <luI, ~"Jt)("J 

roprllO",tabl" OIEr,.incia Uc. 

P'eco' ao~ loccon .re rogl'tored U;;<lem.rts .1 Wellm.rl< 

~Iernational. 

EPAtoll0421 

", ) 
58

I. 1 

I APPROVED AS IS I CHANGES 

Signature 01 Authofized Customer Representatrve Dale 

IIlquit"" 

S-Methoprene 1.2% 

IGR Concentrate 

To Prevent the Development of 

Adult Ftaas for Up To Seven Months 

ACTWE INGR!:OlaIl: 

{Sj-M.lIlop~"e ICAS #6,T33-16-6j ..................... , 1.2% 

OTHm IHGRWIEIITS':" .... _ ........ _ ...... ".98.8% 

TOTAl., , ...... " .. ,", ... ," __ ,' __ "_._, .... _ .... _ .......... ,, ... ,' 100.0% 

'CoIlI,ln, ~Irnloum di,m~I" 

Equll S-MotM;lr¢l1' n% h'J~ Con""nlral. I, "01 m,,"1>otUlOd (I( d~\('butod bl W~lm",k ~terna""'l Of 

Zoeoon, 'ClI<r~ 01 PrWlr". 

i i . Your labels will be p,jnted exactly as 

Signature ot Authorized Customer Representative Date 
59

MATI[-:RlAl TO BE ADDED TO JACKET 

Description: ~II ~-.(\1d-l0r~ );;2'7::, TGL 

C.~Ul'+~le.. pplicable, check all that are attached: f&, new stamped accepted label 

r'-' , l .. _ 

o 

new CSF 

[)g notification u:] fotller: 

, 

Instr"'lctloi1Js: 

Oa~tcl) 

U'l 

ro 

:::I 

0. 

n0 

n 

U'l 

n 

Attach tCis sheet to the top of All material sent to the file room (both loose paper 

and new material in jackets). This sheet will be imaged; a clear description will aid 

in findins' the material in the e-jacket. Remove staples from all material. If 

returnins loose paper then hold together with a binder or paper clip. CSFs should 

be placed in the i:SF folder (if returning jacket) or covered with a red CBr sheet (if 

returning loose paper). Material to be returned to file room should be placed in the 

appropriCl:e bin. 

Reviewer: _-,-M:.ce~n,"-y:..:o",nCl...LA",d",a",m-,-,-"s,--___ Date: APR 26 2011 

Phone: _---1703) 347-8496 Division: BPPD 
60
61

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

Michael Kellogg, Agent 

Envincio LLC 

APR U 20n 

c/o Pyx is Regulatory Consulting, Inc. 

4110136"' St. NW 

Gig Harbor, WA 98332 

RE: Product Name: Equil S-Metboprene 1.2% IGR Concentrate 

EPA Reg. No: 87276-7 

OFFICE OF CHEMICAL SAFETY 

AND POLLUTION PREVENTION 

Application for Label Notification Dated April 21, 2011 to add an optional 

marketing claim per PR Notice 98-10 

Dear Mr. Kellogg: 

The Biopesticides and Pollution Prevention Division is in receipt of your application for 

Notification under Pesticide Registration CPR) Notice 98-10 dated above. A preliminary screen 

of this request has been conducted for its applicability under PR Notice 98-10 and it has been 

detennined that the action(s) requested falls within the scope of PR Notice 98-10. Our records 

have been duly noted, and the label submitted with this application has been stamped 

"Notification Accepted" and will be placed accordingly in our records. 

If you have any questions concerning this action, please feel free to contact Ms. Menyon 

Adams at (703) 347-8496 or email at adams.menyon@epa.gov. 

Sincerely, 

Linda Hollis, Chief 

Biochemical Pesticides Branch 

Biopesticides and Pollution Prevention 

Division (7511P) 
62

pt""s" ,..~d flut " b."', mt>l"tj fo~. 'n [v~n nM.S No. 207 ,"'L 5 

United Statee D Registration opp Idontifier Number 

&EPA Environmental Protection Agency Amendment 

Washington, DC 20460 .( Other 

Application for Pesticide - Section I 

t. Compllnytproduct Numbllr 2. EPA Produot Managar 3. Prop oiled Classifioltion 

87276-7 L. Hollis o Nono D Reltricted 

4. Company/Produot tNemel p"" Envincio llC I Equil S·Melhoprene 1.2% IGR Concenlrale 91 

5. Name end Addross of Applicant (lnc!udfJ ZIP Co dol 6, Expedited Reveiw. In accordance with FIFAA Section 31c)13) 

Envincio LLC (b)l1), my product is similat or identical in composition and labeling 

cto Pyxis Regulatory Consulting, Inc. to: Notification Accepted 4110 136th St. NW EPA Reg. No. 

Gia Harbor. WA 98332 D Chook if this is II now sddross Product Name 

Date: APR j6 2011 

Section - II <eviewer: \, \ AnA'!YD 

D Amendment - Explein bolow. U Final printod lobals in ropsenso to 

Agancy lattar detod 

D Rasubmission in responso to Agency loner dated D ~Mo Too~ Applicetion. 

0 Notilication - Explain below. D Othor - Explain below. 

Exp)anation: Use edditionel pagels) if necessary. IFor seotion I end Seotion 11.1 

Notification of a minor label revision per PRN 98-10 (addition of optional marketing statement). This notification is consistent wilh the 

provisions of PR Notice 98-10 and EPA regulations at 40 CFR 152.46, and no other changes have been made to the labeling or the 

confidential statement of formula of this product. I understand that it is a violation of 18 U.S.C. Sec. 1001 to willfully make any false stalement 

10 EPA. I further understand that if this notification is not consistent with the terms of PR Notice 98-10 and 40 CFR 152.46, this producl may 

be in violation of FIFRA and I may be subject to enforcement action and penalties under sections 12 and 14 of FIFRA. 

Section - III 

1. Motori.1 Thi. ProdUct Will Be P.ck.g.d In: 

Child-Resistent Paokaging Unit Packaging Water Soluble Packaging 2. Typo 01 Containor 

t2]y" ~y" t2j y" E]M"" .( No .( N. 

./ PlOlltic 

N. Gless 

.. Certification must If ~Yes~ No. p~r If ~Yos· No. par Papor 

Unit Packsging wgt. contaln.r Pockago wgt centainer Other tSpacifyl be submitted 1 oz. 10 

3. laotltion of Nat Contonts Information 4. Siletsl Retail Conteiner 5. loootion of lobol Oiroctions 

[{J labal [{J Container 10x1fLoz.and16fl. oz. 

W On Labol 

.~ On Lab~ling accomp.nyin~ producl 

6. Mannor in Which label is Atfixad to Product uUthOgr~h 0 Other 

of Pepar ~'Ued Stonci ad 

Section - IV 

t. Contact Point (Complelo itoms direcrty below for identification of individual to be contt1ctt1d, if necessary, to process this t1pplicalion.j 

Name Titla Talaphono No_ (inoluda Aree Coda) 

Michae) Ke))ogg Agent (253) 853-7369"" , " , , • , ~ > 

Certification , 

, 6. Dete Applic.tion , RecaivicJ I oertify that tha stotamants I hllve mado an this form and all enachments thllrllto are true, eocuroto end oomp'lt1to. " , I acknowlodge thet any knowlingl1y lal50 or misillooing st.temant may bo punishnble by fino or imprisoMlont ur' ; , , ;CS1:31l)'lped) both under IIPplionblelaw. , " , 

:;;;"1IJ~/' 3. ntlll , , , '" , " , 

Agent , .. , , 

4. Typod Nama \ // 5. Deta 

Michae) Ke))ogg V/:U/;/ ' "' " , , , 

EPA Form 8570-1 R ...... 3·94 Previous editions era obsolete. , While - E A p FiMo Co pytgin{ on ~ Y.llow· Ap, , .... Copy 
63

December 3, 2009 

Tn Whom It May Oll1ccrn: 

RE: Letter of Authorization 

Dear Sir or Madam: 

EIIVillcio LLC 

200 Cascade Pointe Lane, Su ite 101 

CUI)', North Carolina 27513 

9\9-6\0-\065 

919-677-6161 (Fax) 

Please let this letter serve to confirm that Pyxis Regulatory Consulting, Inc. is authorized to act as agents 

lor Envillcio LLC (EPA Company Number fpendingj), before the U.S. Enviwilmental Protection Agency 

and stale governmental agencies in al1 matters regarding our pesticide registrations purS(Jant to the Federal 

Insecticide, Flmgicidc and Rodenticide Act ("FIFRA"), 7 U.s.C. § 136 el seq. and state lavl". 

If you have any questions. please do not hesitate to cOlltnct me. 

Sincerely. 

~F~ Randa 11 V. Canady 

FOl1nder & Chief Executive Officer 

cC: Pyxis Regulatol}'CollsI11ting, Inc. 

, > 

I, , 

, 

, - - " , I 
64

PYXIS REGULATORY CONSULTING, INC. 

4110 136th St. NW 

Gig Harbor, WA 98332 

Phone: 253·853·7369 

Fax: 253-853-5516 

www.PyxisRCcom 

COURlER DELIVERY 

Linda Hollis (PM 91) 

Document Processing Desk (NOTIF) 

Office of Pesticide Programs (7504P) 

U.S. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 S. Crystal Drive 

Arlington, VA 22202-4501 

April 21, 2011 

RE: Envincio LLC - Equil S-Methoprene 1.2% lOR Concentrate (EPA Reg. No. 87276-7) 

Notification of a Minor Label Revision per PRN 98-10 

Dear Ms. Hollis, 

On behalf of Envincio LLC please find the enclosed label notification making a minor label revision as 

allowed per PRN 98-10. Envincio is adding an additional optional marketing statement "To Prevent the 

Development of Adult Fleas for Up To Seven Months". This statement appears on pg. I of the label 

under the product name. 

Envincio would like to note this is NOT new language or a new claim. Envincio is simply rephrasing 

existing approved language that currently appears on the Equil S-Methoprene 1.2% lOR Concentrate 

label (i.e., "Treatment with this product on areas where there are flea larvae, that flea larvae will enter 

into, or where flea eggs have been deposited will prevent adult fleas from developing for up to 7 

months.") 

Tn support of this label notification, please find the foHowing: 

I. One (1) copy of the Equil S-Methoprene 1.2% IGR Concentrate label with changes tracked 

2. One (I) copy of the Equil S-Methoprene 1.2% IGR Concentrate label with changes incorporated 

3. Certification with Respect to Label Integrity 

4. One (I) copy of the Equil S-Methoprene 1.2% TGR Concentrate label on CD 

5. Letter of Authorization 

Please contact me by email (Ross@PyxisRC.com)orbyphone(253)853-7369 if you have any questions 

or need any additional infonnation. 

,~ :' 

Michael Kell~ : , 

Enclosures 

, 

, " " . " , , , 

, , , , , " , 

, '" , 

. " , , 
65

Notification Accepted 

[ ] Indicates optional statements Date: 

. APR 26 2011 

Equil S-Methoprene 1.2%"fGR W\/doAlill 

Concentrate 

With [Contains] S-Methoprene Insect Growth Regulator 

[Lasts 210 days[ 

[Makes 1 gallon of spray] 

[Treats 1500 square feet] 

[Breaks the flea life cycle] 

Contains s-methoprene, the active 

ingredient used in Precor®. 

[To Prevent the Emergence of Adult Fleas Indoors] 

[To Prevent the Development of Adult Fleas for Up To Seven Months] 

ACTIVE INGREDIENT: 

(S)-Melhoprene (CAS #65733-16-6) .. ....................... 1.2% 

OTHER INGREDIENTS·: ..................... . .................. 98,8% 

TOTAL:................................. . ....................... . ................... . .. 100.0% 

*Contains petroleum distillates 

If in eyes: 

If on skin or 

ctothing: 

KEEP OUT OF REACH OF CHILDREN 

CAUTION 

FIRST AID 

• Hold eye open and rinse slowly and gently with water for 15-20 

minutes. 

• Remove contact lenses, if present, after the first 5 minutes, then 

continue rinsing eye. 

• Call a poison control center or doctor for treatment advice. 

• Take off contaminated clothing. 

• Rinse skin immediately with plenty of water for 15-20 minutes. 

• Call a poison control center or doctor for treatment advice. 

HOT LINE NUMBER 

Have the product container or label with you when calling a poison control center or doctor, 

or going for treatment You may also contact 1-866-257-4118 for emergency medical 

treatment information. 

NOTE TO PHYSICIAN: This product contains petroleum distillates. If swallowed: 

Immediately call a poison control center or doctor. Do not induce vomiting unless told to do 

so by the poison control center or doctor. Do not give any liquid to the person. Do not give 

anything by mouth to an unconscious person. 

See back panel for additional Precautionary Statements 

For Chemical Spill, Leak, Fire, or Exposure, Call: CHEMTREC 1-800-424-9300 

For Medical Emergencies Only, Call: 866-257-4118 

EPA Reg. No. 87276-7 EPA Es~ 'N6. 

Manufactured for: 

Envincio LLC 

200 Cascade Point Lane, Suite 101 

Cary, NC 27513 

"')!) "" 

,---------------~-~~~, 

Equil S-Methoprene 1.2% IGR C0ncEm~'rate is not 

manufactured or distributed by 1JI..:eI:r,l<;lrk ~ >, ) 

International or Zoecon, sellers of Fr~9.i>r®. ') , , 

Net Contents: 

')', ) 
66

PRECAUTIONARY STATEMENTS 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

CAUTION 

Harmful if absorbed through the skin. Causes moderate eye irritation. Avoid contact with skin, eyes, or 

clothing. Wash thoroughly with soap and water after handling. 

DIRECTIONS FOR USE 

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. 

This product may not be used or referenced as a source of ingredient in the formulation, manufacture, or 

regislration of any other products without prior written authorization from Envincio LLC. 

PRODUCT INFORMATION 

This product contains the active ingredient S-Methoprene, an insect growth regulator that prevents fleas 

from maturing into adults by acting in the early stages of development. Treatment with this producl on 

areas where there are flea larvae, that flea larvae will enter into, or where flea eggs have been deposited 

will prevent adult fleas from developing for up to 7 months. Because this product is a growth regulator, it 

does not affect fleas that have reached full development or fleas that have reached the pupae stage. 

IMPORTANT NOTE: In order prevent fleas from being introduced indoors, it is important to treat pels to 

ensure that they do not carry fleas. Treat pets with a product registered with the EPA and labeled for 

such a use. 

MIXING DIRECTIONS 

Prepare product as a diluted spray solution by adding 1 ounce of this product to 1/2 gallon of water in a 

mixing container and agilate thoroughly. Then add an additional 1/2 gallon of water and agitate again, 

resulting in one gallon of spray solution. 

TANK MIXES 

If there is already a high population of fleas at the biting (adult) stage, tank-mix this product with an EPA 

registered product that is labeled for use to control fully developed/adult fleas. Add the product you are 

tank mixing with this product to 1/2 galion of water in the mixing container and agitate thoroughly. Then 

add this product to the mixing container and agitate further. Finally, add an additional 1/2 galion of water 

to the mixing container to create one galion of spray solution and agitate the mixture thoroughly. 

APPLICATION RATE 

Apply this product at the rate of 1 gallon diluted spray solution (see "MIXING DIRECTIONS" above) per 

1500 square feet of surface area, 

METHOD OF APPLICATION 

In order to prevent fleas and flea infestation, apply this product before the flea season. Users/applicators 

must ensure that they shake the solution well prior to each use. 

Apply to areas where fleas, flea eggs and flea larvae are or are likely to be located such as surfaces 

where pets sleep, carpets, rugs and upholstered furniture (including on and under cushions and throw 

rugs) using a low pressure sprayer with a fan tip typically used for indoor applications. 

NOTE: This product typically will not stain materials that would not be stained by water alone. However,,, 

prior to full application a test should be made by applying a small amount of diluted soiuUon to an ,,:" 

inconspicuous area in order to determine whether staining will take place. ; :; , 

Avoid contact with areas that have been treated until they are dry. , " , , 

" , , , 

, , " " 
67

STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage and disposal. 

PESTICIDE STORAGE: Store in a cool place away from heat or open flame. 

PESTICIDE DISPOSAL: Wastes resulting from the use of this product may be disposed of on site or at 

an approved waste disposal facility, 

CO NT AINER HANDLING: Nonrefillable container. Do not reuse or refill this container. Triple rinse 

container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents 

into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the 

container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or 

a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. 

Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in 

a sanitary landfill, or by incineration, or, if allowed by state and local authorities, by burning. If burned, 

stay out of smoke. 

CONDITION OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 

NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and 

Liability before buying or using this product. If the terms are not acceptable, return the product at once, 

unopened, and the purchase price will be refunded. 

The Direction for Use of this Product must be followed carefully. It is impossible to eliminate all risks 

inherently associated with the use of this product Ineffectiveness or other unintended consequences 

may result because of such factors as manner of use or application, weather, presence of other materials 

or other influencing factors in the use of the product, which are beyond the control of Envincio LLC or 

Seller. To the extent consistent with applicable law, all such risks shall be assumed by Buyer and User, 

and Buyer and User agree to hold Envincio LLC and Seller harmless for any claims relating to such 

factors. 

Envincio LLC warrants that this product conforms to the chemical description on the label and is 

reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks referred to 

above, when used in accordance with directions under normal use conditions. This warranty does not 

extend to the use of this product contrary to label instructions, or under abnormal conditions or under 

conditions not reasonably foreseeable to or beyond the control of Seller or Envincio LLC, and Buyer and 

User assume the risk of any such use. To the extent consistent with applicable law, ENVINCIO LLC 

MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE 

NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS STATED ABOVE. 

To the extent consistent with applicable law Envincio LLC or Seller shall not be liable for any incidental, 

consequential or special damages resulting from the use or handling of this product. To the extent 

consistent with applicable law, THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE 

EXCLUSIVE LIABILITY OF ENVINCIO LLC AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, 

INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, 

NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR 

HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE 

PRODUCT OR, AT THE ELECTION OF ENVINCIO LLC OR SELLER, THE REPLACEMENT OF THE 

PRODUCT. 

Envincio LLC and Seller offer this product, and Buyer and User accept it, subject to the foregoing : ~" 

Conditions of Sale and Limitation of Warranty and Liability, which may not be modified~exdert by written 

agreement signed by a duly authorized representative of Envincio LLC. : " 

Precor and Zoecon are registered trademarks of Wellmark International, 

EPA20110421 

, , " 

, " 

, '" , , " , 

", , 
68

Certification with Respect to Label Integrity 

version: 9111/02 

I certify that the information (including, but not limited to, text, tables, and graphics) 

contained in the electronic file identified below by file name and submitted with this 

certification is the same information as that on the paper copies of these documents 

included with this submission. 

IPROPOSED LABEL 

Date Submitted 

EPA Registration # to EPA Electronic file name 

87276-7 April 21, 2011 087276-00007.20110421.Equil S-Methoprene 

1.2% lOR Concentrate notification Jabe1.pdf 

I certify that the statements that I have made on this form are true, accurate, and 

complete. I acknowledge that any knowingly false or misleading statements may be 

punishable by fine or imprisonment or both under applicable law. 

Si nature Date 

Michael Kellogg 

Name (typed) 

Agent 

Title 

, , , , , 0,.,,, " 

, " 

" , , , " , 

, , " , 
69

I 

Pr{OCESSING ElECTkONIC lABELS 

(rev. 115/09, tch) 

If e-Iabel submitted via XML e-submission (not on CD-ROM), you may wish to find e-Iabel in 

Documentum, save e-Iabel to "My Documents", add e-Iabel to ELL, start below at step 5. 

Initial E-Label per application (on CD·ROM with paper via ITRMD) 

I JTRMD receives 

paper submissjon 

wi e-Jabel on CD 

b Save copy of elabel from ELL to 

My Documents 

1U Send annotated 

e-Iabel to registrant 

via elnall 

~ Tracking 

record added to 

OPPIN 

I Review label 

III QCCOPIOOlo, .k,p 10 .IOp 20) 

1 r File print of 

annotated e-Iabel 

and email in jacket 

J ITRMO adds 

e-Jabel to ELL 

in-process 

~ Add comments 

to e-Iabel 

Ioovo. ~dd 'w,l1, 

<o",mO"I," 10 ~Ienomu 

review 

U Add annotated elabel to ELL 

out-process 

4 ITRMD sends 

paper submission 

to AD/BPPD/RD 

~ Connect ELL 

record with 

OPPIN S# 

II Print annotated elabel 

1; Close 

submission in 

OPPIN 

Resubmission (via email to staffer or PM) 

14 Receive email 

submission wI e· 

label attached 

I~ Add tracking 

record to 

OPPIN 

1\, Add e-Iabel 

10 ELL 

in·process 

I~ Save copy of elabels {old & new) from 

ELL to My Documents 

I~ Compare old and 

new labels with 

Acrobat 

JU Print e.label, " Mail stamped 

stamp, write cover label & cover 

letter letter to registrant 

!u.o 'P",'I ",II, F1,on~m. 'J 

process - big picture 

1- create QPPIN tracking 

2- put label in ELL; link to S# 

3· save ELL label to MyDocuments 

4- compare I comment 

5- outprocess 

review 

:l;i File stamped 

label & cover letter 

in jacket 

out-process 

11 Connect ELL 

record with 

QPPIN S# 

(if revisions needed repeat steps 8-19) 

~J Add cover 

letterto ELL 

(m",ld<llcry il acc.pl~~ 

\'.1111 ccmm"""J 

<4 Close 

submiss'lon 'In 

OPPIN 

techniques to know 

- filename for e-Iabels 

- "print with filename" 

- compare I comment 

- printing with comments 
70

There is an ELECTRONIC LABEL for this action 

You can use Acrobat to compare the e-Iabel to the previous version (and find the 

changes). You can also use Acrobat to mark-up the e-Iabel with your comments. 

If e-Iabel was submitted via 

CD-ROM with paper application 

then you will find e-Iabel in 

Electronic Label Library 

It tllD e-lol1el is not found In IIle ELL /lIen it was probably not nnmed 

correclly and could not be eillored In/a llie ELL. HowQvor, tllO file 

Ciln be retrieved from 1110 CD w/lie/I Is retained by Ille Front End 

or If e-Iabel was submitted via 

XML E-Submission (no paper) 

then you will find e-Iabel in 

Documentum 

See overview of processing e-Iabels on other side of this sheet. 

If you have any questions on e-Iabels, please contact one of your division e-Iabel experts: 

AD Willie Abney 308-1689 

Renae Whitaker 308-7003 

Tracy Lantz 308-6415 

BPPD 

RD Tom Harris 308·9423 
71

MATERIAL TO BE ADDED TO JACKET 

REG #: 87276-7 

Description: new registration 

if applicable, check all that are attached: 

L8J new stamped accepted label CJ) 

(l) 

L8J :::l 

new CSF Cl.. 

r-f" 

D 0 

notification n 

CJ) 

D other: n 

Instructions: 

Attach this sheet to the top of ALL material sent to the file room (both loose paper 

and new material in jackets). This sheet will be imaged; a cieardescription will aid 

in finding the material in the e-jacket. Remove staples from all material. If 

returning loose paper then hold together with a binder or paper clip. CSFs should 

be placed in the CSF folder (if returning jacket) or covered with a red CBI sheet (if 

returning loose paper). Material to be returned to file room should be placed in the 

appropriate bin. 

Reviewer: John Fournier Date: 2/23/2011 

Phone: (703) 308-0169 Division: BPPD 
72

! , 

u.Y~~,*r~\l.~1jtMJt81~'tVOH A'i;'" -Y 

'8;' PAReg. 

Office of Pesticide Programs Number: Date ofIssuance: ~ U Biopesticides and Pollution Prevention Division 

\, -} (7511C) 87276·7 FEB 15 2011 1200 Pennsylvania A venue NW 

~L. AAO'ie:- Washington, DC 20460 Tennof UNCONDITIONAL 

NOTICE OF PESTICIDE Issuance: 

Name of Pesticide Product: 

_X_ Registration __ Re-registration 

(under FIFRA, as amended) Equil S-Methoprene 1.2% IGR 

Concentrate 

Name and Address of Registrant (include ZIP Code): 

Envincio LLC 

200 Cascade Pointe Lane, Suite 101 

Cary, NC 27513 

• •• >·.CO>..,>" .. ··,>'.·....·. '.""',.""".' ." '.' ..... ". .;; ..... '. '::~ ?t~::;;C?han'i~~sJP;)ageliifg'AiffeJ:iIig ,i~':,suks~9,e::fi,pn:r!h~f;~'~c'eP:f~d :ir! :,co,nnectioir with:. this registration must be 

":s,ub;pl#~d'':to,;~(f:*(5~?iii~~;fjy~fh~<i';Bfop'e'~HtiCie:~f:~4 p,oil#fib,il;Prey,~'nti(}ri:tjiviS.~on'priorto'use,:O{ihe label iri I '~qAlll]:et;Cey>[ri::,anY:;'c'p,l#,~p,(hiii~ric~>,(ii! ,:this':pfodu~f81~a)?s,:;r¢ledo 'tile :a1?ov~"Er A' r,egistTa1lon' 'Dumper. ' 

On the basis of information furnished by the registrant, the above named pesticide is hereby registered under the 

Federal msecticide, Fungicide and Rodenticide Act. 

Registration is in no way to be construed as an endorsement or recommendation of this product by the Agency. In 

order to protect health and the envirorunent, the Administrator, on his motion, may at any time suspend or cancel the 

registration of a pesticide in accordance with the Act. The acceptance of any name in connection with the registration 

of a product under this Act is not to be construed as giving the registrant a right to exclusive use of the name or to its 

use if it has been covered by others. 

This product is unconditionally registered in accordance with FIFRA Sec. 3(c)(5) provided you: 

L Submit and/or cite all data required for registration} reregistration of your product under FIFRA 

section 3(c)(5) and section 4 when the Agency requires all registrants of similar products to submit 

such data. 

2. Make the following label change before you release the product for shipment: Revise the EPA Registration 

Number to read, "EPA Reg. No. 87276~7." 

3. Submit three (3) copies of the revised final printed labeling before you release the product for 

shipment. 

4. Submit within 1 year after the Date of Registration acceptable data packages for Guideline Studies: Storage 

Stability study (OCSPP GLN: 830.6317) and Corrosion Characteristics study (OSCPP GLN: 830.6320) for this 

product. 

If these conditions are not complied with, the registration will be subject to cancellation in accordance with FIFRA 

sec.6(e). Your release for shipment of the product constitutes acceptance of these conditions. A stamped copy of the 

label is enclosed for your records. 

~,gn"ture 01 ApproVIng omc, .. !: 

rw-£l;- Date: 

w- ytLdJ FEB 15 2011 

w COHCURR!!HC!S 

SYM~ esticides and llution Preven ion Division 75//Y 15 If 1:[JIV . .. ..... ... SURNAME PA Form 857 6 "f-" I\A e1' Z£:4(: 1!,t;~Z;··· ................. . ................. . ................ ................ ..... _ ........ - .............. _ . DATE . 15"e-b II 

EPA Foon 1320-1A (1/90) 

, I OFFICIAL FtLE COpy 
73

[ ] Indicates optional statements 

; 

Equil S-Methoprene 1.2% IGR 

Concentrate 

With [Contains]iS-Methoprene Insect Growth Regulator 

[Lasts 21 0 day~] 

[Makes 1 gallol") of spray] Contains s-methoprene, the active 

[Treats 1500 s9uare feet] ingredient used in Precor®. 

[Breaks the flea life cycle] Ace 

[To Prevent thel Emergence of Adult Fleas Indool!T\ 

. fEBU2 

ACTIVE INGREDIENT: 

(S)-Melhopren~ (CAS #65733-16-6) ............. u ... · thii·l'tdiiiii· "',.,, """"""" , , '"'' "" ,1.2% 

OTHER INGREDIENTS"': .......... . ............ and.~odentJc:ItN.~~.::.~~~~!~, .... 98 8% 

TOTA~: ........... : .......... : .. : .................................. .tht.~.~=r ..... ~.~.... . .. 100.0% 

*Contalns petro;leum distillates EPA Reo. No. '&' 7 J. 7 (" - 7 

on or 

clothing: 

KEEP OUT OF REACH OF CHILDREN 

CAUTION 

• Hold eye open and rinse slowly and gently with water for 15-20 

minutes. 

• Remove contact lenses, if present, after the first 5 minutes, then 

continue rinsing eye. 

II I 

• i i 

• Rinse skin immediately with of water for 15-20 minutes. 

~ ________ ~~I~ I ~~~~~~~~ 

or i you or 

treatment. You may also contact 1-8:66-257-4118 for emergency medical 

information. 

i ill I , 

Imnnedj~tE"Y cali a poison I center or . Do not induce vomiting unless told to de;' " 

so by the poison control center or doctor. Do not give any liquid to the person. Do not give, , 

anything: by mouth to an unconscious person. ' ' I ~ , , 

See back panel for additional Precautionary Statements 

ForChemical Spill, Leak, Fire, or Exposure, Call: CHEMTREC 1-800-424-3300 

For Medical Emergencies Only, Call: 866-257-4118 .", , 

EPA Reg. No. i87276-xx 

Manufactured (or: 

Envincio LLC 

200 Cascade Point Lane, Suite 101 

Cary, NC 27513 

EPA Est: No. 

Equil S-Methoprene 1.2% IGR Concentrate is'r,ct·' 

manufactured or distributed by Wellmark 

International or Zoecon, sellers of Precor®. 

Net Contents: 
74

PRECAUTIONARY STATEMENTS 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

CAUTION 

Harmful if absorbed through Ihe skin. Causes moderate eye irritation. Avoid contact with skin, eyes, or 

clothing. Wash thoroughly with soap and water after handling. 

DIRECTIONS FOR USE 

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. 

This product may not be used or referenced as a source of ingredient in the formulation, manufacture, or 

registration of any other products without prior written authorizati(;ln fran; Envincio LLC, 

PRODUCT INFORMATION 

This product contains the acflve 'Ingredient S-Methoprene, an insect growth regulator that prevents fleas 

from maturing into adults by acting in the early stages of development. rreatment with this product on 

areas where there are flea larvae, that flea larvae will enter into, or wiler!?' fief! eggs have been deposited 

will prevent adult fleas from developing for up to 7 months. Because. this. product is a growth regulator, it 

does not affect fleas that have reached full development or fleas that have reached the pupae stage. 

IMPORTANT NOTE: In order prevent fleas from being introduced indoors, it is important to treat pets to 

ensure that they do not carry fleas. Treat pets with a product registered with the EPA and labeled for 

such a use. 

MIXING DIRECTIONS 

Prepare product as a diluted spray solution by adding 1 ounce of this product to 1/2 gallon of water in a 

mixing container and agitate thoroughly. Then add an additional 1/2 gallon of water and agitate again, 

resulting in one gallon of spray solution. 

TANK MIXES 

If there is already a high population of fleas at the biting (adult) stage, tank~mix this product with an EPA 

registered product that is labeled for use to control fully developed/adult fleas. Add the product you are 

tank mixing with this product to 1/2 gallon of water in the mixing container and agitate thoroughly. Then 

add Ihis product to the mixing container and agitate further. Finally, add an additional 1/2 gallon of water 

to the mixing container to create one gallon of spray solution and agitate the mixture thoroughly. 

APPLICATION RATE 

Apply this product at the rate of 1 gallon diluted spray solution (see "MIXING DIRECTIONS" above) per 

1500 square feet of surface area. 

METHOD OF APPLICATION 

In order to prevent fleas and flea infestation, apply this product before the flea season. Users/applicators 

must ensure that they shake the solution well prior to each use. 

Apply to areas where fleas, flea eggs and flea larvae are or are likely to be located such as surfaces 

where pets sleep, carpets, rugs and upholstered furniture (including on and under cushions and throw 

rugs) using a low pressure sprayer with a fan tip typically used for indoor applications. 

NOTE: This product typically will not stain materials that would not be stained by water alone. However, 

prior to full application a test should be made by applying a small amount of diluted solution to an 

inconspicuous area in order to determine whether staining will take place. 

Avoid contact with areas that have been treated until they are dry. 

2 
75

STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage and disposal. 

PESTICIDE STORAGE: Store in a cool place away from heat or open flame. 

PESTICIDE DISPOSAL: Wastes resulting from the use of this product may be disposed of on site or at 

an approved waste disposal facility. 

CONTAINER HANDLING: Nonrefillable container. Do not reuse Or refill this container. Triple rinse 

container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents 

into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the 

container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or 

a mix tank or store rinsate for later use or disposal, Drain for 10 seconds after the flow begins to drip. 

Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in 

a sanitary landfill, or by incineration, or, if allowed by state and local authorities, by burning. If burned, 

stay out of smoke. 

CONDITION OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 

NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of Warranty and 

Liability before buying or using this product. If the telTlls are not acceptable, return the product at once, 

unopened, and the purchase price will be refunded. 

The Direction for Use of this Product must be followed carefully. It is impossible to eliminate all risks 

inherently associated with the use of this product. Ineffectiveness or other unintended consequences 

may result because of such factors as manner of use or application, weather, presence of other materials 

or other influencing factors in the use of the product, which are beyond the control of Envincio LLC or 

Seller. To the extent consistent with applicable law, all such risks shall be assumed by Buyer and User, 

and Buyer and User agree to hold Envincio LLC and Seller harmless for any claims relating to such 

factors. 

Envincio LLC warrants that this product conforms to the chemical description on the label and is 

reasonably fit for the purposes stated in the Directions for Use, subject to the inherent risks referred to 

above, when used in accordance with directions under normal use conditions. This warranty does not 

extend to the use of this product contrary to label instructions, or under abnormal conditions or under 

conditions not reasonably foreseeable to or beyond the control of Seller or Envincio LLC, and Buyer and 

User assume the risk of any such use. To the extent consistent with applicable law, ENVINCIO LLC 

MAKES NO WARRANTIES OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE 

NOR ANY OTHER EXPRESS OR IMPLIED WARRANTY EXCEPT AS STATED ABOVE. 

To the extent consistent with applicable law Envincio LLC or Seller shall not be liable for any incidental, 

consequential or special damages resulting from the use or handling of this product. To the extent 

consistent with applicable law, THE EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE 

EXCLUSIVE LIABILITY OF ENVINCIO LLC AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, 

INJURIES OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, CONTRACT, 

NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) RESULTING FROM THE USE OR 

HANDLING OF THIS PRODUCT, SHALL BE THE RETURN OF THE PURCHASE PRICE OF THE 

PRODUCT OR, AT THE ELECTION OF ENVINCIO LLC OR SELLER, THE REPLACEMENT OF THE 

PRODUCT. 

Envincio LLC and Seller offer this product, and Buyer and User accept it, subject to the foregOing 

Conditions of Sale and Limitation of Warranty and Liability, which may not be modified except by written 

agreement signed by a duly authorized representative of Envincio LLC. 

Precor and Zoecon are registered trademarks of Wellmark International. 

[EPA approval date] 

3 
76

"j 

PYXIS RhGULATORY CONSULTING, IN\.-. 483551·00 

Phone: 253-853~7369 

Fax: 253-853-5516 

www.PyxisRC.com 

4110 136!iI St. NW 

Gig Harbor, WA 98332 

COURIER DELIVERY 

John Fournier (BPPD) 

Document Processing Desk (APPL) 

Office of Pesticide Programs (7504P) 

U.S. Environmental Protection Agency 

Room SA900, One Potomac Yard 

2777 S. Crystal Drive 

Arlington, VA 22202-4501 

January 18, 2011 

RE: Envincio LLC - Equil S~Methoprene 1.2% lOR Concentrate (EPA File Symbol No. 87276-T) 

Response to Agency Correspondence dated January 13,2011 

Dear Mr. Fournier, 

On behalfofEnvinco LLC and in response to your email dated January 13,2011, please find the (..I).yl,o_:;~d 

supporting documentation for the Equil S-Methoprene 1.2% IGR Concentrate applicatio'1 for regi~tration. 

1. Application for Pesticide Registration (EPA Form 8570~1) 

2. Revised Confidential Statements of Formula (Basic and three (3) Alternate F'}r)l111lations C:ated 

January 13,2011) 

3. Copies of offer-to-pay letters sent to companies on the Data Submitters List for S~methoprene 

4. Product Specific Data: 

Volume 1 830.1650 Kellogg, M. Description of Quality Control Procedures and Measures 

48355101 Used During the Formulation Process of Equil S-Methoprene 1.2% 

IGR Concentrate. SUpplemental Report to MRlD No. 48300101. 

As I mentioned in my email of January 14,2011, a storage stability and corrosion characteristic study is 

currently underway for Equil S-Methoprene 1.2% lOR Concentrate. We expect the final study report to 

be available for submission to the Agency by January 1,2012. 

Please feel free to call me if you have any questions or need any additional information. 

Michael Kellogg 

Enclosures 
77

Hi John, 

Re: Slightly Revised Memo: 87276-T [;j 

Sadaf Shaukat to: John Fournier o tI t9/201 t 02: t3 PM 

The CSF is acceptable and so is the description of the quality control. I would just make sure that all the 

companies originally cited in the data matrix (there were quite a few) are covered with these letters they 

sent. Ifthat looks good, then I think it's a go! 

Thanks! 

Sadaf Shaukat 

Biologist 

U.S. Environmental Protection Agency 

Biopesticides & Pollution Prevention Division (7511 P) 

1200 Pennsylvania Ave., NW 

Washington, DC 20460 

shaukat.sadaf@epa.gov 

703-347-8670 

John Fournier Hey Sadaf, 1 spoke to the registran1 on the phon ... 

From: 

To: 

Date: 

Subject: 

Hey Sadaf, 

John Fournier/DC/USEPAlUS 

Sadaf ShaukatJDC/USEPAJUS@EPA 

o tI t9/20 t t 09:23 AM 

Re: Slightly Revised Memo: 87276~T 

01/19/2011 09:23:55 AM 

I spoke to the registrant on the phone last week and they sent off (almost) everything we needed. 

The guy I spoke to said that he was sending hard copies in the mail but he e-mailed me advance copies of 

the letters with offers to pay, revised CSFs with box 4 filled, and revised study with quality control 

measures. The only thing they are not addressing is the storage/stability, which they'll submit at a later 

date and will be a condition of registration. If you think this description of quality control is ok, I can go 

ahead and register the product. 

[attachment "2011 0113 Equil S-Methoprene 1.2% IGR Concentrate revised CSF's.pdf' deleted by Sadaf 

ShaukatlDC/USEPAlUS] [attachment "201011 04 Envincio S-Methoprene 1.2% IGR Concentrate OTPs 

Sent.pdf' deleted by Sadaf ShaukatiDC/USEPAlUS] [attachment "2011 0113 Equil S-Methoprene 1.2% 

IGR Concentrate 61 series report supplement.pdf' deleted by Sadaf ShaukatiDC/USEPAlUSj 

Thanks, 

John Fournier 

Regulatory Action Leader, Biochemical Pesticides Branch 

Biopesticides and Pollution Prevention Division 

Office of Pesticide Programs (7511 P) 

u.S. Environmental Protection Agency 

One Potomac Yard 

2777 S. Crystal Drive 

Arlington, VA 22202 

fournier.john@epa.gov 

(703) 308-0169 (phone) 

(703) 305-0118 (fax) 

http://www.epa.gov/pesticides 
78

UNITED STATES ENVIRONMENTAl PROTECTION AGENCT 

WASHINGTON, D.C. 20460 

OFFICE Of CHEMICAL SAfUY AND POlUTION PREVENTlDN/omCE OF PUTICIDE PRDGRAMS 

MEMORANDUM JAN 1 0 2011 

DATE: 

SUBJECT: 

FROM: 

TO: 

January 10,2010 

Science Review in Support of the Registration of Equil S-Methoprene 1.2% IGR 

Concentrate, Containing 1.2% S-Methoprene as Its Active Ingredient. 

Decision Number: 442373 

DP Number: 384495 

EPA File Symbol Number: 87276-T 

Chemical Class: Biochemical 

PC Code: 105402 

CAS Number: 65733-16-6 

Active Ingredient Tolerance Exemptions: OCSPP 180,1033 

MRID Numbers: 48300101-03 

Type of Review: Product Chemistry 

Sadaf Shaukat, Biologist 

Biochemical Pesticides Branch 

Biopesticides & Pollution Prevention Division (7511P) 

John Fournier, Regulatory Action Leader 

Biochemical Pesticides Branch 

Biopesticides & Pollution Prevention Division (7511P) 

ACTION REQUESTED 

Envinco LLC requests registration of Equil S-Methoprene 1.2% lGR Concentrate, an end-use 

product to prevent the emergency of adult fleas indoors. In support of this registration, the 

registrant has submitted Product Chemistry data (MRID 48300101-03) including a proposed 

product label and Confidential Statement of Formula (CSF) dated 11/0211 O. 
79

S-Melhoprene 

PC Code: 105402 

2 

RECOMMENDATIONS AND CONCLUSIONS 

DP Number: 384495 

EPA Reg. No.: 87276-T 

1. The product chemistry submission is SUPPLEMENTAL, but upgradeable pending 

resolution of deficiencies. 

MRID 483001 0 1: Supplemental, but Upgradeable 

MRID 48300102: Acceptable 

MRlO 48300103: Acceplable 

a. The registrant must add the registration number in Box #4 of the eSF. 

b. Quality control and assurance measures must be described for the manufacturing process. 

c. Results of one~year storage stability and corrosion characteristics studies must be 

submitted for the EP. (OCSPP 830.6317, 830.6320) 

Note to RAL: The registrant writes that they will make an offer to pay cited companies for acute 

toxicity data. The registrant must submit proof that they have offered to pay these companies. qv 

STUDY SUMMARIES 

Product Chemistry 

The EP contains S-Methoprene which is an insect growth regulator that prevents fleas from 

maturing into adults by acting in the early stages of development. The active ingredient 

nominally comprises 1.2% of the end-use product by weight. There are several inert ingredients 

in the product. The eSF and product label are in agreement regarding the active ingredient 

content. 

A list of the starting materials was submitted in MRlD 48300101. A description of the 

manufacturing process was submitted. 

Also, the registrant submitted an acceptable discussion on the formation of impurities. In 

summary, no impurities are introduced during the formulation. No impurities are fonned by the 

interaction of its components. No chemical reactions occur which could lead to the formation of 

new by-products. 

The enforcement analytical method was sufficiently identified as gas chromatography using 

flame ionization detection. Stability and corrosion characteristics data were not submitted and are 

required. The submitted physical and chemical property data are sufficient and can be found in 

the table below. Methods used to determine each physical/chemical property were submitted. 

*Please see confidential appendix for details. 
Page 80-*Manufacturing process information may be entitled to confidential treatment*
81

S-Melhoprene 

PC Code: 105402 

4 

TABLE 1. Physical and Chemical Propertics for Corvus MA 

Guideline Reference No.!Property Dcscription of Result 

830.6302 Color Very light yellow 

830.6303 Physical State Liquid 

830.6304 Odor Faint aliphatic hydrocarbon odor 

830.6314 OxidationlRed uction Water 

Initial: mixture formed white 

emulstion 

I minute: no change 

24 hours: mixture separated into 

transparent colorless liquid over 

white emulsion 

Ammonium Phosuhate 

Initial: off~white emulsion 

I minute: no change 

24 hours: separated into colorless 

liquid over white emulsion 

Iron uowder 

Initial: very light yellow w/grey 

sediment 

I minute: no change 

24 hours: no change 

Potassium P!,;:rmanganate 

Initial: purple, opaque liquid 

I minute: no change (temp 

increased by 5 degrees) 

24 hours: light brown, opaque 

liquid 

Gasoline 

Initial: very light yellow 

transparent liquid 

I minute: no change 

24 hours: no change 

830.6315 FlanunabilitylFlash Point 203°F 

830.7000 pH (20°C) 5.44 

830.7100 Viscosity (24°C) 3.3 centipoise 

830.7300 Relative!Bulk Density (24°C) 0.820 glcm (6.84Ibslgal) 

, Data from MRlD 48300103 

cc: S. Shaukat, J. Fot/rnier, BPPD Science Review File, IHAD/ARS 

S. Shaukat, FT, PY-S: ]/]0/]0 

DP Number: 384495 

EPA Reg. No.: 87276-T 

Methods 

Visual inspection 

Visual inspection 

Olfactory inspection 

Aliquots oftest subslance mixed 

with various reactants (water, 5% 

v/v anunonium phosphale, iron 

poweder, 5% w/v potassium 

permanganate, gasoline) 

Setaflash 

Electrometric, on a I % dispersion 

Capillary viscometry 

Hydrometer 
82

Memorandum 

Date: 1124/11 

To: PM 91, Regulatory Manager 

From: Information Services Branch, ITRMD 

Your receipt of this data submission is not an 

indication that MRIDs for the enclosed studies have 

been posted to OPPIN. 

We expect that it will be approximately 5 days 

from the above date before the study-level data is 

available in OPPIN. 

If you have any questions about this process, 

please contact Teresa Downs (305-5363). 

This is a: %cully accepted submission 

o partially accepted submission 

o rejected submission 
83

Administrative 

Materials 
84

PI ... o ",.d /fI#t ' O~ ,.v.rso bf/fo,.CtlmDl.tiM ,,,m,. " I ADDrovo OM. 0.2070..nnM "", ,MR_" 

Unitlld States § Registration OPP Identifillr Number 

&EPA Environmental Protection Agency Amendment 

Woshington, OC 20460 .f Other 

Application for Pesticide· Section I 

I. Company/Product Number 2. EPA Prodl./ct Manager 3. Proposed Classification 

87276-T John Foumier o None o Restrictad 

4. Compony/Product INamol PM. 

Envincio LLC I Equil S-Methoprene f .2% IGR Concentrate BPPD 

5. Nome lind Addross of Applicont IIncludo ZIP Codo/ 6. Expedited Reveiw. In accordance with FIFAA Section 3{cH3) 

Envincio LLC Ib)!i(, my product is similar Of identical in composition and labeling 

c/o Pyxis Regulatory Consulling, Inc. to: 2724-352 41 to 136th 81. NW EPA Reg. No. 

GiQ Harbor. WA 98332 D Chock ff this fs II now oddross Product Name 

Zoecon RF-291 Emulsifiable Concenlrate with Pro cor 

Section· II 

0 Amendment - Explein below. U Rnal printed lebels in repsonse to 

Agency letter doted 

0 Rosubmisslon in response to Agency letter doted 1113/2011 0 "Ma Too· Application. 

0 Notification - Explllin belew. 0 Other - Expillin bolow. 

Explanation: Use edditionel pegor:;1 ir neconory. , , IFor soction I ond Section 11.1 >'"" "", , , 

Submission of revised Confidential Stalements of Formula, offer-to-pay leiters and description of quality cohtro~ prOcedures ;?Jld measures 

used during the formulation process of Equil S·Methoprene 1.2% IGR Concentrate per the Agency email dated Jahuary t3, 2(\t1. , , , , , > , , """ , , 

" , , , , , " , , , j 

, > , , , , - - Section· III , , , " " , - t. Materiel Thi. Product WIll Be Peckeged In: "'.H , 

Child-Rosistllnt Packaging Unit Packaging Wator Solublll Pockoging 2. Typo of Container - , ,,~,>, 

t2jv" ~v" [ZJ v" EJ M".I ' 

.f No .f No No .; Plastic 

GlO$1,I 

" Certification must If ·Yos· No. per If ·Yos· No. par Pepllr 

Unit Packoging wgt. contolnor Packogo wgt container Othor ISpecifyl btl submitted 1 oz. to 

3. Locetion ef Net Contents Information 4. Size(s) Rotoil Cont.inor 5. Locetion of Label Oiroctions 

[{J label [{J Container 10 X 1 fl. oz. and t6 fl. oz. ~ On Labol .,- On Labeling accompanying product 

6. Mannor in Which Lobal is Affixed to Preduct ~Uthegr'Ph D Othor 

of Poper p'lued Stonci .d 

Section· IV 

f. Contllct Point /Comp/oto i10ms diroctly below to, idtmlificotion of rndivfdual to btl contllctad, if nsc(Jssary, ro proCtlSS lhis IIpp/icstron./ 

Nllme Titlo Tolophone No. {Include ArGa Codol 

Michael KeUogg Agent (253) 853-7369 

Certification 6. Ooto Appnclllion 

I certify that the statomants I hovo mlKlo on this form and allattllchments thorpto aro true, eccurate and complote. Receivad 

I Ilcknewh'fdgo that IIny knowlinglly falslI er misloading statemont moy be punhihoblu by fino or imprisorvnont or (Stamped) both undor applicobl. law. 

2. Signature 3. TItle 

Ab-~ Agen1 

4. Typed N~;O 5.0ata 

Michael KeUogg t/;,f;J/ 

EPA Form 8570·1IRev. 3 -941 ProvlOu$ adltlons ero obsolote. White· EPA File Copy (onglnal) Yellow - AppHcent Copv 
85

I PYXIS l<.£GULATORY CONSULTING, L,'::. 

4110 J36lh St. NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CERTIFIED MAIL, RETURN RECEIPT REQUESTED 

70101060000194753886 

ADM Alliance Nutrition,lnc. 

1000 North 30th Street, Box Cl 

Quincy, IL 62305 

RE: Offer-to-Pay 

Dear SirfMadam: 

Phone: 253~853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1.2% IGR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.P.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30, 2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S~methoprene. Therefore, in accordance with Section 3(c)(I)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(1 )(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

ofFIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the terms of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

,~~ f"JK. /~ 

Janelle Kay 

Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 
86

1 

I 

PYXIS It£GULATORY CONSULTING, 1,,';. 

4110 J36th St. NW 

Gig Harbor, WA 98332 

November 4, 20 I 0 

VIA CERTIFIED MAIL. RETURN RECEIPT REQUESTED 

70101060000194753749 

Ambands 

PQBox 1019 

Salem, VA 24153 

RE: Offer-to-Pay 

Dear Sir/Madam: 

Phone: 253-853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil ,S-Methoprene; ,] ,2% TOR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3(c)(1 )(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(I)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to detennine which data are subject to the compensation regulations 

ofFIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the tenns of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

, 

Janelle Kay 

Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 
87

PYXIS REGULATORY CONSULTING, n,";. 

4110 136th St. NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CERTIFIED MAIL. RETURN RECEIPT REQUESTED 

70101060000194753701 

B2E Biotech, LLC 

1501 East Woodfield Road 

Suite 200 West 

Schaumurg, IL 60173 

RE: Offer-to-Pay 

Dear SirlMadam: 

Phone: 253-853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1,2% IGR Concentrate." 

Envincio LLC intends on using the cite-all under selective method afdata support (40 C.F,R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3(c)(1)(F) ofthe Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

1) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(1 )(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to detennine which data are subject to the compensation regulations 

ofFIFRA, and the amount and tenns of compensation,}f any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the tenns of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

Janelle Kay 

Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 
88

I PYXIS tlEGULATORY CONSULTING, ",C. 

4110 136th St. NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CERTIFIED MAIL. RETURN RECEIPT REQUESTED 

70101060000194753787 

B2E Corporation 

1501 East Woodfield Road 

Suite 200 West 

Schaumurg, IL 60173 

Dear Sir/Madam: 

Phone: 253-853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "EquiI S-Methoprene 1,2% IGR Concentrate." 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F.R. § 152.95) 

to satisfY acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S.methoprene. Therefore, in accordance with Section 3(c)(1)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and, efficacy data (EPA Guideline Requirements 

810.3500. 870.1100. 870.1200. 870.1300. 870.2400, 870.2500. and 870.2600) to the extent required 

by FIFRA section 3(c)(l)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

ofFIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the terms of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

Janelle Kay 

Agent for Envincio LLC 

,. 

cc: R. Canady; Envincio LLC 
89

J 

PYXIS "lGULATORY CONSULTING,!..'::. 

4110 136th St. NW 

Gig Harbor, WA 98332 

November 4,2010 

VIA CERTIFIED MAIL, RETURN RECEIPT REQUESTED 

70101060000194753770 

Babolna Bioenvironmental Centre Ltd. 

PO Box 5126 

Valdosta, GA 31603 

RE: Offer-to-Pay 

Dear SirfMadam: 

Phone: 253-853-7369 

Fax; 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1.2% IGR Concentrate." 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3(c)(1)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay. compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(1 )(F) contingent on approval of the registration, and 

3) Offer to commen-ce negotiations to determine which data are subject to the compensation regulations 

ofFIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the terms of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

,?4 

Janelle Kay 

Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 

.1 r, 
90

I PYXIS "EGULATORY CONSULTING, L,C. 

4110136th St.NW 

Gig Harbor, WA 98332 

November 4, 20 J 0 

VIA CERTIFIED MAIL. RETURN RECEIPT REQUESTED 

7010 10600001 94753848 

Chattem, Inc. 

1715 West 38th Street 

Chattanooga, TN 37409 

RE: Offer-to-Pay 

Dear SirlMadam: 

Phone: 253v 853-7369 

Fax'. 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene J .2% IGR Concentrate." 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F.R, § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30, 2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3(c)(I)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

1) Notification of its intent to apply for registration, 

2) Offer to' pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500. 870.1100. 870.1200. 870.lJOO. 870.2400. 870.2500. and 870.2600) to the extent required 

by FIFRA section 3(c)( I )(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

of FIFRA, and the amount and terms of compensation, if any, due, 

In your retum correspondence, please indicate any items of data for which you intend to request 

compensation and the tenns of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

Janelle Kay 

Agent for Envincio LLC 

cc: R, Canady; Envincio LLC 
91

I 4110 \36th 31. NW 

GigHarbor,WA 98332 

November 4, 20 I 0 

PYXIS "lWULATORY CONSULTING, l .. C. 

VIA CERTIFIED MAIL, RETURN RECEIPT REQUESTED 

70101060000194753824 

Control Solutions, Inc. 

427 Hide Away Circle 

Cub Run, KY 42729 

Dear SirlMadam: 

Phone: 253-853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1.2% JGR Concentrate." 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F.R. § 152.95) 

to satisry acute toxicity and efficacy data requirements only. In EPA's September 30, 2010 Listing of 

Pesticide Data Subm itters, your company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3(c)(J)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

1) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

8103500, 870. 1100, 870,1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(J )(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

of FIFRA, and the amount and terms of compensation, ifany, due, 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the terms of compensation that you propose, if any, If we have not received your 

response within 90 days, we will assume that no compensation is requested, 

Thank you for your cooperation, 

~~ ;IZJ/t! 

, " 

Janelle Kay 

Agent for Envincio LLC 

cc: R, Canady; Envincio LLC 
92

I PYXIS ,JGULATORY CONSULTING, L,-';, 

4110 136m St. NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CERTIFIED MAIL RETURN RECEIPT REQUESTED 

70101060000194753763 

Egis Phannaceuticals Public Limited Co. 

1150 18th Street, NW, Suite 1000 

Washington, DC 20036 

Dear SirlMadam: 

Phone: 253·853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-metnoprene as the active 

ingredient The proposed product name is "Equil S-Methoprene 1.2% IGR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F,R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30, 2010 Listing of 

Pesticide Data Submitters, your company is included as on:e of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3 (c)(l)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FTFRA), as amended, this letter constitutes Envincio LLC's: 

1) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870,2600) to the extent required 

by FIFRA section 3(c)(J)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

of F1FRA, and the amount and tenns of compensation, if any, due. 

In your retum correspondence, please indicate any items of data for which you intend to request 

compensation and the tenns of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested, 

Thank you for your cooperation. 

~~#-

Janelle 

,42/( 

Kay 

~ 

Agent for Envincio LLC ! ,', \ 

cc: R, Canady; Envincio LLC 
93

J 

PYXIS KEGULATORY CONSULTING, L,C. 

4110 J36th St. NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CERTIFIED MAIL. RETURN RECEIPT REQUESTED 

70101060000194753725 

Hartz-B2E LLC 

7 12 5th Street, Suite A 

Davis, CA 95616 

RE: OffeHo-Pay 

Dear Sir/Madam: 

Phone: 253·853·7369 

Fax: 253·853·5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient The proposed product name is "Equil S-Methoprene 1.2% IGR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F,R, § 152.95) 

to satisfY acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S~methoprene. Therefore, in accordance with Section 3(c)(l)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500. 870.1100. 870.1200. 870.1300. 870.2400. 870.2500. and 870.2600) to the extent required 

by FIFRA section 3(c)(l)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to detennine which data are subject to the compensation regulations 

ofFIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the tenns of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

~~ Janelle Kay 

Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 
94

J 

) 

PYXIS hcGULATORY CONSULTING, J,.~. 

4110 J36th St. NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CERTIFIED MAIL. RETURN RECEIPT REQUESTED 

70101060000194753688 

Loradochem, Inc. 

4061 North 156th Drive 

Goodyear, AZ 85338 

Dear SirlMadam: 

Phone: 253-853-7369 

Fax: 253-853-5516 

www.Pyx:isRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1.2% lOR Concentrate." 

Envincio LLC intends on using the cite-aU under selective method of data support (40 C.F.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30, 2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore. in accordance with Section 3(c)(I)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(I)(F) contingent on approval ofthe registration, and 

3) Offer to commence negotiations to detennine which data are subject to the compensation regulations 

ofFIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the terms of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

',0£ ~ Janelle Kay ~ Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 
95

I 

PYXIS fikGULATORY CONSULTING, 1.,C. 

4110 136th St. NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CERTIFIED MAIL. RETURN RECEIPT REQUESTED 

70101060000194753817 ' 

Management Contract Services, Inc. 

PO Box 5209 

Valdosta, GA 31603 

Dear Sir/Madam: 

Phone: 253·853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient The proposed product name is "Equi! S-Methoprene 1.2% IGR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30, 2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S.methoprene. Therefore, in accordance with Section 3(c)(l){F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500,870.1100,870.1200,870.1300,870.2400, 8[70.2500, and 870.2600) to the extent required 

by FIFRA section 3{c){I)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to detennine which data are subject to the compensation regulations 

ofFIFRA, and the amount and tenns of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the terms of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

~~- ;12K r-::r 

Janelle Kay 

Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 
96

J 

PYXIS "EGULATORY CONSULTING, 1,,(;. 

4110 1361h St. NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CER TJFJED MAIL. RETURN RECEIPT REOUESTED 

70101060000194753732· . 

Marketquest, Inc. 

PO Box 1019 

Salem, VA 24153 

RE: Offer-to-Pay 

Dear SirlMadam: 

Phone: 253~8S3~ 7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1.2% IGR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C,F.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30, 2010 Listing of 

Pesticide Data Submitters, YOUT company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3(c)(l)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(J)(F) contingent on approval o(the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

of FIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the tenns of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

~~- /OK /~ Janelle Kay 

Agent for Envincio LLC 

cc; R. Canady; Envincio LLC 
97

] 

j 

PYXIS ,,£GULATORY CONSULTING, L.'::. 

4110 J36!h St. NW 

Gig Harbor, WA 98332 

November 4, 20 I 0 

VIA CERTIFIED MAIL. RETURN RECEIPT REQUESTED 

70101060000194753800 

Merial Limited 

3239 Satellite Blvd. 

Bldg. 500, Office 113 

Duluth, GA 30096 

RE: Offer-to-Pay 

Dear SirlMadam: 

Phone: 253-853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1.2% IGR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C,F.R, § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3(c)(l)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(I)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

ofFIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the terms of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

Janelle Kay 

Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 
98

I PYXIS hEGULATORY CONSULTING, L-:. 

4110 1361h St. NW Phone: 253~853-7369 

Gig Harbor, WA 98332 Fax; 253-853-5516 

www.PyxisRC.com 

November 4, 20 I 0 

VIA CER Tl flED MA IL, RETURN RECEIPT REQUESTED 

70101060000194753718 

Residential Exposure Joint Venture (RElY) 

900 17th Street NW, Suite 300 

Washington, DC 20006 

Dear Sir/Madam: 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1.2% IGR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.P.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S~methoprene. Therefore, in accordance with Section 3(c)( I)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

1) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3( c)(I)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

ofFIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items df data for which you intend to request 

compensation and the tenus of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested, 

Thank you for your cooperation, 

~ Janelle 

;0;< 

Kay 

~ Agent for Envincio LLC 

cc: R, Canady; Envincio LLC 
99

/ 

PYXIS h£GULATORY CONSULTING, I,,';. 

4110 J36th St. NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CERTIFIED MAIL. RETURN RECEIPT REQUESTED 

70101060000194753879 

Sergeant's Pet Care Products Inc. 

2625 South 158th Plaza 

Omaha, NE 68130 

RE: Offer-ta-Pay 

Dear SirlMadam: 

Phone: 253 w 853 w 7369 

Fax: 253 w 853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1,2% lOR Concentrate." 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as one ofthose who have data on file at the Agency 

for Swmethoprene. Therefore, in accordance with Section 3(c)(1 )(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

1) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870,1300,870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)( I )(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

of FIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the terms of compensation that you propo~e, if any, If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

;:;~ p~ k4 

Janelle Kay 

Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 

, , 
100

PYXIS h€GULATORY CONSULTING, I,,";. 

4110 136!h St. NW 

Gig Harbor, WA 98332 

November 4, 20 I 0 

VIA CERTIFIED MAIL, RETURN RECEIPT REQUESTED 

70101060000194753794 

Spray Drift Task Force 

1900 K Street, NW 

Washington, DC 20006 

RE: Offer-to-Pay 

Dear SirlMadam: 

Phone: 253~853~7369 

Fax: 253~853~5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient The proposed product name is "Equil S-Methoprene 1.2% lOR Concentrate." 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.P.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3(c)(I)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100. 870.1200, 870.1300. 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(I)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to detennine which data are subject to the compensation regulations 

ofFIFRA, and the amount and terms of compensation, if any, due. 

In your retum correspondence, please indicate any items of data for which you intend to request 

compensation and the tenns of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation js requested. 

Thank you for your cooperation. 

~ Janelle 

/21;:< 

Kay 

~ Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 
101

I PYXIS h£GULATORY CONSULTING, J;,-:. 

4110 136th St. NW Phone: 253~853~7369 

Gig Harbor, WA 98332 Fax: 253~853-5516 

www.PyxisRC.com 

November 4, 2010 

VIA CERTIFIED MAIL, RETURN RECEIPT REQUESTED 

70101060000194753862 

The Hartz Mountain Corp. 

400 Plaza Drive 

Secaucus, NJ 07094 

RE: Offer-to-Pay 

Dear SirlMadam: 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1.2% lOR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F,R, § 152,95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30, 2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S~methoprene. Therefore, in accordance with Section 3(c)(I)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870,2600) to the extent required 

by FIFRA section 3(c){l)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

of FIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the terms of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

~ Janelle 

Agent 

!8~ for 

Kay 

Envincio 

~ LLC 

cc: R. Canady; Envincio LLC 
102

I PYXIS rtEGULATORY CONSULTING, ... C. 

4110 136th S1, NW 

Gig Harbor, WA 98332 

November 4, 20 I 0 

VIA CERTIFIED MAIL, RETURN RECEIPT REQUESTED 

7010 10600001 94753756 

Valent Biosciences Corporation 

870 Technology Way, Suite 100 

Libertyville, IL 60048 

Dear SirlMadam: 

Phone: 253·853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1.2% IGR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.P.R. § 152.95) 

to satisfY acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as Qne Qf those who have data on file at the Agency 

for S·methoprene. Therefore, in accordance with Section 3(c)(I)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's; 

1) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(l)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

of FIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the tenns of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

Janelle Kay 

Agent for Envincio LLC 

cc; R. Canady; Envincio LLC 
103

PYXIS hcGULATORY CONSULTING, I,,";. 

4110136Ul St.NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CERTIFIED MAIL, RETURN RECEIPT REQUESTED 

70101060000194753855 

WeIImark International 

1501 E. Woodfield Road 

Suite 200 West 

Schaumburg, IL 60173 

RE: Offer-to-Pay 

Dear Sir/Madam: 

Phone: 253~853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end-use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S-Methoprene 1.2% fOR Concentrate," 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F.R. § 152.95) 

to satisfY acute toxicity and efficacy data requirements only. In EPA's September 30, 2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3(c)(l)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Qffer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(I)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

of FIFRA, and the amount and tenus of compensation, if any, due. 

In your return cOlTespondence, please indicate any items of data for which you intend to request 

compensation and the telms of compensation that you propose, if any. If we have not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

~ RJ~ ~ t. 

Janelle Kay 

Agent for Envincio LLC 

cc: R. Canady; Envincio LLC 
104

PYXIS REGULATORY CONSULTING, INC, 

4110 136th St. NW 

Gig Harbor, WA 98332 

November 4,2010 

VIA CERTIFIED MAIL, RETURN RECEIPT REQUESTED 

70101060000194753831 

ZEP Commercial Sales and Service 

1310 Seaboard Industrial Blvd. NW 

Atlanta, GA 30318 

RE: Offervto·Pay 

Dear SirlMadam: 

Phone: 253 v 853v 7369 

Fax: 253-853-5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end·use product containing S-methoprene as the active 

ingredient. The proposed product name is "Equil S·Methoprene 1.2% lOR Concentrate." 

Envincio LLC intends on using the cite-all under selective method of data support (40 C.F.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30, 2010 Listing of 

Pesticide Data Submitters, your company is included as one of those who have data on file at the Agency 

for S-methoprene. Therefore, in accordance with Section 3 (c)(I)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guidl~line Requirements 

810.3500, 870.11.00, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(I)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to determine which data are subject to the compensation regulations 

ofFIFRA, and the amount and tenns of compensation, ifany, due. 

In your return correspondence, please indicate any items of data for which yot,1 intend to request 

compensation and the terms of compensation that you propose, if any. If we hav(~ not received your 

response within 90 days, we will assume that no compensation is requested. 

Thank you for your cooperation. 

~ Janelle 

NK 

Kay 

~ Agent for Envincio LLC 

cc; R. Canady; Envincio LLC 
105

PYXb REGULATORY 

i 

CONSULTING, ,j .NC. 

4110 136th St. NW 

Gig Harbor, WA 98332 

November 4, 2010 

VIA CERTIFIED MAIL, RETURN RECEIPT REQUESTED 

70101060000194753695 

Zocor Incorporated 

70 I Eighth Street NW 

Suite410 

Washingtop, DC 2000 I 

RE: Offer~to~Pay 

Dear Sir/Madam: 

Phone: 253~853~7369 

Fax: 253~853~5516 

www.PyxisRC.com 

Envincio LLC is applying for registration of an end~use product containing S~methoprene as the active 

ingredient. The proposed product name is "Equil S~Methoprene 1.2% IGR Concentrate." 

Envincio LLC intends on using the cite~alJ under selective method of data support (40 C.F.R. § 152.95) 

to satisfy acute toxicity and efficacy data requirements only. In EPA's September 30,2010 Listing of 

Pesticide Data Submitters, your company is included as one 9fthose who have data on file at the Agency 

for S~methoprene. Therefore, in accordance with Section 3(c)(I)(F) of the Federal Insecticide, Fungicide 

and Rodenticide Act (FIFRA), as amended, this letter constitutes Envincio LLC's: 

I) Notification of its intent to apply for registration, 

2) Offer to pay compensation for acute toxicity and efficacy data (EPA Guideline Requirements 

810.3500, 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, and 870.2600) to the extent required 

by FIFRA section 3(c)(I)(F) contingent on approval of the registration, and 

3) Offer to commence negotiations to detennine which data are subject to the compensation regulations 

of FIFRA, and the amount and terms of compensation, if any, due. 

In your return correspondence, please indicate any items of data for which you intend to request 

compensation and the terms of compensation that you propose, if any. If we haVI~ not received your 

response within 90 days, we will aSSume that no compensation is requested. 

Thank you for your cooperation. 

:;:;;P4 

Janelle Kay 

Agent for Envincio LLC ( 

cc: R. Canady; Envincio LLC 
106

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

January 24, 2011 

JANELLE KAY 

PYXIS REGULATORY CONSULTING, INC. 

ENVINCIO LLC 

4110 1136TH STREET, NW 

GIG HARBOR, W A 98332-

Report of Analysis for Compliance with PR Notice 86-5 

OFFICE OF 

PREVENTION, PESTICIDES AND 

TOXIC SUBSTANCES 

Thank you for your submittal of 19-JAN-ll. Our staff has completed a preliminary 

analysis of the material. The results are provided as follows: 

Your submittal was found to be in full compliance with the standards for submission of 

data contained in PR Notice 86-5. A copy of your bibliography is enclosed, annotated with 

Master Record ID's (MRIDs) assigned to each document submitted. Please use these numbers in 

all future references to these documents. Thank you for your cooperation. If you have any 

questions concerning this data submission, please raise them with the cognizant Product 

Manager, to whom the data have been released. 
107
108

j 

PYXIS Rhu'ULATORY CONSULTING, INc. 483561-00 

Phone: 253-853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

4110 136th St. NW 

Gig Harbor, WA 98332 

COURIER DELIVERY 

John Fournier (BPPD) 

Document Processing Desk (APPL) 

Office of Pesticide Programs (7504P) 

U.s. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 S. Crystal Drive 

Arlington, VA 22202-4501 

January 18,2011 

RE: Envincio LLC - Equil S-Methoprene 1.2% IGR Concentrate (EPA File Symbol No. 87276-T) 

Response to Agency Correspondence dated January 13,2011 

Dear Mr. Fournier, 

On behalf of Envinco LLC and in response to your email dated January 13,2011, please find the (.l)'ilo:;~d 

supporting documentation for the Equil S-Methoprene 1.2% IGR Concentrate applicatio'1 for regbtration. 

1. Application for Pesticide Registration (EPA Form 8570-1) 

2. Revised Confidential Statements of Fonnula (Basic and three (3) Alternate F'lTTTllllations Gated 

January 13.2011) 

3. Copies of offer-to-pay letters sent to companies on the Data Submitters List for S-methoprene 

4. Product Specific Data: 

Volume 1 830.1650 Kellogg, M. Description of Quality Control Procedures and Measures 

48355101 Used During the Fonnulation Process of Equil S-Methoprene 1.2% 

lOR Concentrate. Supplemental Report to MRlD No. 48300101. 

As I mentioned in my email of January 14, 2011, a storage stability and corrosion characteristic study is 

currently underway for Equil S-Methoprene 1.2% IGR Concentrate. We expect the final study report to 

be available for submission to the Agency by January 1,2012. 

Please feel free to call me if you have any questions or need any additional infonnation. 

Michael Kellogg 

Enclosures 

, "l 
109

U'-"I., $:lLrL f"',;Qr"r.<, '-j"Clr;\',,' :'~.r.:. 

Olkl 01 ~I L\I.:,OL ~'09'j 

1,,10'lT.!I,D'" '1.101,l{;.r u,e S.rY<.\ :)"'q,on 

Irdolffill,crr. S''';''~I\ B"",,.· 

8EPA 

Pl\1: q I 

• 

CI-IEMJCAl No.: ______ ---'--___ _ 

The jacket for this action can be 

requCoSted through the J . .i.CKETS system 
110

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

November 23, 2010 

PYXIS REGULATORY CONSULTING, INC. 

ENVINCIO LLC 

4110 1136TH STREET, NW 

GIG HARBOR, WA 98332-

Report of Analysis for Compliance with PR Notice 86-5 

OFFICE OF 

PREVENTION, PEST1CIDES AND 

TOXIC SUBSTANCES 

Thank you for your submittal of IS-NOV -10. Our staff has completed a preliminary 

analysis of the material. The results are provided as follows: 

Your submittal was found to be in full compliance with the standards for submission of 

data contained in PR Notice 86-5. A copy of your bibliography is enclosed, annotated with 

Master Record ID's (MRlDs) assigned to each document submitted. Please use these numbers in 

all future references to these documents. Thank you for your cooperation. If you have any 

questions concerning this data submission, please raise them with the cognizant Product 

Manager, to whom the data have been released. 
111

T "",t F "'" ,,~+ JJ." , I' J q ) / 0 

,("",f f!(l1.A J"" ~" 3/'i 1'°« 

Ph<5ei-. 1)'1//0 

Q'J 0 If h~>c :t O~ '3> 

~hdC 9/ 2)'1)/0 

fh"H <f 3/'11'0 11 
112

PYXIS h,,;GULATORY CONSULTING, 11-<":. 

4110 136th St.NW 

Gig Harbor, WA 98332 

COURIER DELIVERY 

Linda Hollis (PM 91) 

Document Processing Desk (REGFEE) 

Office of Pesticide Programs (7504P) 

U.S. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 S. Crystal Drive 

Arlington, VA 22202-4501 

November 17,2010 

483001-00 

Phone: 253-853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

RE: Envincio LLC - Equil S-Methoprene 1.2% lOR Concentrate (EPA Reg. No. 87276- ) 

Application for a New Pesticide Registration 

Dear Ms. Hollis, 

On behalf of Envinco LLC please find the enclosed application materials for registration of Equil SMethoprene 1.2% lOR Concentrate an end-use product containing S-methoprene as the active ingredient. 

In support of this application, we submit the following documents: 

1. Application for a New Pesticide Registration (EPA Form 8570-1) 

2. Receipt ofPRIA pre-payment from pay.gov 

3. Confidential Statements of Formula (Basic and three (3) Alternate Formulations dated November 

2,2010) 

4. Formulators Exemption Statement (EPA Form 8570-27) 

5. Five (5) copies of the proposed labeling 

6. Certification With Respect to Label Integrity 

7. Electronic copy of the proposed label on CD 

8. Certification with Respect to Citation of Data (EPA Form 8570-34) 

9. Agency Internal Use Copy of the Data Matrix (EPA Form 8570-35) 

10. Public File Copy ofthe Data Matrix (EPA Form 8570-35) 

II. Letter of Authorization 

12. Product Specific Data: , c c ~ c ( . Volume 1 830.1550,830.1600, Miller, R. Product Identity and Composition, Description of Materials 

Used to Produce the Product, Description of the Fonnulabo~cProcess, 

48300101 

830.1650,830.1670, 

and Discussion of Fonnation ofImpurities.- (. , , , . -~ 48300102 Volume 2 830.1700, 830.1750, Miller, R. Equil S-Metboprene 12% IGR C~OPPrl:lvate Pt~lil(rifl1.ry 830.1800 Analysis, Certified Limits and Enforcement Al-ifl\y.:ical M~tboQs. . , 48300103 Volume 3 830.6302 through Miller, R. (S)-Methoprene IGR EC Producf(s~6n-ltstry. PTdduCt 

830.7950 Properties: Color, Physical State, Odor, Ox'iMti6niReductiorl': 

Chemical Incompatibility, Flammability, pH, Viscosity, a~iDccsitv. 

Equil S-Methoprene 1.2% IGR Concentrate is substantially similar to the currently registered 'p'fulluct 

(EPA Reg. No. 2724-352). Envincio LLC believes this application falls under Category R300 (44) since 
113

L. Hollis 

November 17, 2010 

Page 2 of2 

Equil S-Methoprene 1.2% lOR Concentrate is a new product, substantially similar in composition and use 

to a registered product, only product chemistry data are being submitted to support the application for 

registration and the cite-aU option under the selective method is being used to support product specific 

acute toxicity and efficacy data requirements. In addition, the technical source(s) of active ingredient are 

based on registered source(s) of supply and therefore, Equil S-Methoprene 1.2% lOR Concentrate 

qualifies for Fonnulators Exemption for S-methoprene generic data requirements. 

Please note: (S)-Methoprene IGR EC and Equil S-Methoprene 1.2% IGR Concentrate are the same 

product. Envincio requested the product name be changed to Equil S-Methoprene 1.2% IGR Concentrate 

shortly before submitting this application for registration. 

We trust you will find this application complete and in compliance with the requirements for registration 

under FIFRA. Please feel free to call me if you have any questions or need any additional infonnation. 

Michael Kellogg 

Enclosures 

• C ( , 
114

Endnotes for Data Matrix for Equil S.Methoprene 1.2% IGR Concentrate 

1 830.1620 _ Per OPPTS 830.1000, these data are not required for the registration of an 

end-use product. See 830.1650 for formulation process information. 

2 830.1700 _ This product does not consist solely of the technical grade active ingredient (TGAI) and is 

not produced by an integrated system, therefore, per OPPTS 830.1700, these data are not required. 

, 830.6313, 830.7050, 830.7200, 830.7220, 830.7370, 830.7550, 830.7560, 830.7570, 830.7840, 

830.7860 and 830.7950 - Per OPPTS 830.1000, these data are not required for the registration of an 

end-use product. 

4830.6316 _ This product does not have explosive characteristics; therefore these data are not required. 

Please refer to the Confidential Statement of Formula for additional information on the composition of 

Equil S-Methoprene 1.2% IGR Concentrate. 

s 830.6317, 830.6320 - Envincio LLC is currently conducting storage stability and corrosion characteristic 

studies to satisfy guidelines 830.6317 and 830.6320, respectively. Per PR Notice 92-5, storage 

stability data are not required to be submitted unless specifically requested by the Agency. OPPTS 

830.6317 and 830.6320 guidelines allow the corrosion characteristics study and storage stability study 

to be conducted simultaneously. Envincio LLC will submit these data upon completion. As these 

studies take over a year to complete, Envincio LLC requests that a conditional registration for Equil SMethoprene 1.2% IGR Concentrate be granted on the submission of these data. 

6830.6319 _ The Equil S-Methoprene 1.2% IGR Concentrate proposed labeling recommends dilution 

with water, not oil; therefore, these data are not required. 

7830.6321 _ This product is not proposed for use around electrical equipment. Therefore, these data are 

not applicable nor are these date required. 

8830.7520 _ These data are not required for Equil S-Methoprene 1.2% IGR Concentrate because it is not 

water insoluble and is not a fibrous material. 

Page 1 of 1 
115

Certification with Respect to Label Integrity 

version: 9111/02 

I certify that the information (including, but not limited to, text, tables, and graphics) 

contained in the electronic file identified below by file name and submitted with this 

certification is the same information as that on the paper copies of these documents 

included with this submission. 

IPROPOSED LABEL 

Date Submitted 

EPA Registration # to EPA Electronic file name 

87276-xx November 17, 2010 087276-xxxxx.20 1 01117. Equi1 S-Methoprene 

1.2% IGR Concentrate label.pdf 

I certify that the statements that I have made on this form are true, accurate, and 

complete. I acknowledge that any knowingly false or misleading statements may be 

punishable by fine or imprisonment or both under applicable law. 

Date 

Michael Kellogg 

Name (typed) 

Agent 

Title 
116

NEW APPLICATIONS 

DATE: NOV j 8 2010 

FILE NUMBER: y7 :)76 - T 

PEP (OPPIN ENTRY) tV !!/.!1/;).olo 

(Initial & date) . 

f'ILE ROOl\1: _____ _ 

(Initia! & date) 

SIG: 

(Initial & date) 

FILE ROOM: ------

(Initial & date) 

_/ ASSIGN TO PM .?! _ (NO DATA) 

__ JACKET TO SHELF (DATA) 
117

21-Day Screen Completed by 

Contractor 

21-Day Expires on I'L - 9 - 10 

Jacket # S 7 Z 7 G - T 

MRID# L.( r"S 00 I 

Content Screen: Recommended to @Fail 

86-5 Review: assedl aiIed/NA 

Transfer This Jacket to: 

I 
118

PRIA 2 - 21 Day Content Screen Review Worksheet 

(EPA/OPP Use Only) 

3/23/09 

21 Day Screen Start Date: /I - I 8- - I 0 / 

Experts In-Processing Signature: rtF J!rlAA/-",,(J'TM/ Date 1/- Z ']-10 Fee Paid: Yes ~ 

Division management contacted on issues No Yes Date 

EPA Reg. Number: 'is 72. 7 r. EPA Receipt Date: II-IS-/O 

1 

2 

3 

4 

5 

6 

Items for Review Yes No N/A* 

Application Form (EPA Form 8570-1)(link to form) signed & complete 

induding package type X 

Confidential Statement of Formula all boxes completed, form signed, and \-

dated Form . to 

a) All inerts (link to http://www.epa.gov/opprdOOllinertsl), 

including fragrances, approved for the proposed uses (see 

Footnote 

Certification with Respect to Citation of Data (EPA Form 8570-34) (Link to V 

form) completed and signed (N/A if 100% repack) f\ 

Certificate and data matrix consistent 

If applicant is relying on data that are compensable, is the offer 

to pay statement included. (see Footnote B) 

yes no 

Exemption ~F~0;;nn~~*~i'7iTn~t~ofu;;;;\-+--~-~--1 and signed (N/A if source is unregistered or applicant owns the 

Data Matrix (EPA Form 8570-35) (Link to form) both internal and external 

copies (PR 98~5) (Link to PR 98~5) completed aod signed (N/A if 100% 

Selective Method 

b) Cite-All (Fee category experts use) 

c) Applicant owns all data (Fee category experts use) 

5 Copies of Label (link to http://www.epa.gov/oppfeadl/1abelingflrm!) 

(Electronic labels on CD are encouraged and guidance is available)( link to V 

http://www.epa.gov/pesticides/regulating/registering/submissions/index.htm#labels "\ 

1 
119

7 Is the data package consistent with PR Notice 8685 (link to PRN 86-5) X 

Notice of Filing (link to 

8 httl!!lIwww.el!a.gov/l!esticideslregulatin2ltolerance I!etitions.htm) included 

with petitions (link to 

http://www.epa.govil'esticidesire2ulatin!!itolerances.htm) X 

9 If applicable for conventional applications, reduced risk rationale (link to 

http://www.epa.gov/opprd001/workplan/reducedrisk.html) ARequired Data (link to 

httl!!lIwww.el!a.gov/l!esticides/regulatin2fdata reguirements.htm) and/or 

data waivers. See Footnote C. 

a) List study (or studies) not included with application 

10 

2 
120

Comments: 

~* Ach~ 

'* ;if 

\ 

, 

, 

, 

, 

\ 

* N/A - Not Applicable 

Footnotes 

/ 

I ;, ';"'" "{- .. ;-0. \ 

A During the 21 day initial content review, all CSFs will be reviewed to detennine 

whether all inerts listed, including fragrances, are approved for the proposed uses. If an 

unapproved inert is identified, the applicant must either 1) resolve the inert issue by, for 

example, removing the inert, substituting it with an approved inert, submitting 

documentation that EPA approved the inert for the proposed pesticidal uses, correcting 

mistakes on the CSF, etc. or 2) provide the data to support OPP approval of the inert or 3) 

withdraw the application. Removing or substituting an inert ingredient will require a new 

CSF and may require submission of data. All information, fOTITIs. data and 

documentation resolving the inert issue must have been received by the Agency or the 

application withdrawn within the 21 day period. otherwise, the Agency will reject the 

application as described below. 

To successfully complete this aspect of the 21 day initial content screen, applicants are 

strongly encouraged to verify that all inert ingredients have been approved for the 

application's uses even if a product is currently registered by consulting the inert Web 

3 
121

site [link to http://www.epa.gov/opprdOOllinerts/lists.html1 and if the inert is not 

approved, to obtain the necessary inert approval prior to submitting an application 

to register a pesticide product containing that inert ingredient. Some inert 

ingredients are no longer approved for food uses or certain types of uses. The name 

and/or CAS number on a CSF must match the name and CAS number on this web site. 

Simple typographical errors in the name or CAS number have resulted in processing 

delays. 

If an inert is not listed on the inert ingredient web site and the applicant believes that the 

inert has been approved, the applicant should contact the Inert Ingredient Assessment 

Branch (IlAB) at inertsbranch@epa.gov and resolve the issue. Copies of the 

correspondence with IIAB resolving the issue should accompany the application. All 

new inerts except PIP inerts are reviewed by IIAB. The JIAB should also be contacted 

for any questions on what supporting data needs to be submitted for and the Agency's 

inert review process. Questions on PIP inerts should be directed to the Chief of 

Microbial Pesticides Branch [Link to 

http://www.epa.gov/oppbppdllbjopesticides/contactsbppd.htm ] . 

When a brand, trade, or proprietary name of an inert ingredient is listed on a CSF, 

additional infonnation such as an alternate name of the inert, CAS number or other 

infonnation [link: to http://www.epa.gov/opprdOOllinerts/tips.pdf] must also be included 

to enable the Agency to detennine if it has been approved. Each component of an inert 

mixture (including a fragrance) must be identified. In some cases, the supplier of the 

mixture or fragrance may need to provide this infonnation to the Agency. Prior to the 

Agency's receipt of an application, applicants must arrange with a proprietary mixture or 

fragrance supplier to provide the component information to the Agency or promptly upon 

EPA's request. If the inert ingredients in a proprietary blend (including fragrances) 

cannot or are not identified or provided within the 21-day content review period, the 

Agency will reject the application. 

During the 21 day content review, applicants should submit infonnation to the individual 

identified by the Agency when the applicant is infonned of an unapproved inert. 

Unapproved Inerts Identified on CSFs 

All applications except conventional new products and PIPs 

Once an unapproved inert is identified on a CSF, the Agency will contact the 

applicant with the following options: 

1. Correct the application by, for instance, correcting the inert's identity or CAS 

number, providing documentation that the inert has been approved, or 

removing the unapproved inert from the CSF or replacing it with one that is 

approved for the application's uses; or 

2. Submit the information and data needed for the Agency to approve the 

unapproved inert If this option is selected and implemented, the Agency may 

request an extension in the PRlA decision review timeframe to accommodate 

the inert review/approval process; 

4 
122

3. Withdraw the application (the Agency retains 25% of the full fee for the fee 

category estimated); or 

If none of these options is selected and implemented by the applicant within the 

21 day content review period, the Agency will reject the application and retain 

25% of the full fee of the category identified. 

Conventional New Product Applications 

When the Registration Division identifies an unapproved inert on a CSF with an 

application for a new product that the applicant has not identified as requiring an 

inert approval (R311, R312 or R313), it will contact the applicant with the 

following options: 

1. Correct the application by, for instance, correcting the inert's identity or CAS 

number, providing documentation that the inert has been approved, or 

removing the unapproved inert from the CSF or replacing it with one that is 

approved for the application's uses; or 

2. Submit the information and data needed for the Agency to approve the 

unapproved inert, including any required petition to establish or amend a 

tolerance or exemption from a tolerance. (This option may change the PRIA 

category for the application, which could require a longer decision review 

time and a larger fee. If additional fees are due, they must be received by the 

Agency within the 21 day content review period.) 

3. Withdraw the application (the Agency retains 25% of the full fee for the fee 

category estimated); or 

If none of the above options is selected and implemented during the 21-day 

content-review period, the Agency will reject the application and retain 25% of 

the appropriate fee for the new product-inert approval category. 

PIP Applications 

"When the Biopesticide and Pollution Prevention Division identifies an 

unapproved inert on a PIP CSF and a request to approve the inert does not 

accompany the application, it will contact the applicant with the following 

options: 

1. Correct the application by, for instance, correcting the spelling or name of the 

inert to that in 40 CFR 174, or providing documentation that the inert has been 

approved; or 

2. Submit the information and data needed for the Agency to approve the 

unapproved inert. If an inert ingredient tolerance exemption petition is 

required, the petition must be received by the Agency and the B903 fee paid 

within the 21 day period. If this option is selected and implemented, the 

Agency will discuss harmonizing the timeframe for both actions. 

5 
123

3. Withdraw the application (the Agency retains 25% of the full fee for the fee 

category estimated)~ or 

If none of the above options is selected and implemented during the 21 day 

content review period, the Agency will reject the application and retain 25% of 

the fee. 

B. A policy on documentation of offers to pay is still being developed, however, for a 

me-too or fast track (similar/identical) new product, R300 or A530, an application 

without the necessary authorizations of offers to pay will be placed into either R301 or 

A53l. The Agency recommends that authorizations of offers to pay be submitted with 

other PRIA applications to avoid delays in the Agency's decision. 

c. Biopesticide applicants are advised to contact the Agency and discuss study waivers 

prior to submitting their application to the Agency. Documentation of such discussions 

should be submitted with the study waiver. 

6 
124

UNIl .... .J' STATES ENVIRONMENTAL PROTECTlO~ AGENCY 

WASHINGTON, D.C. 20460 

November 23,2010 

OPP Decision Nmnber: D-442373 

EPA File Symbol or Registration Nwnber: 87276-T 

OFFICE OF 

PREVENTION, PESTICIDES AND 

TOXIC SUBSTANCES 

Product Name: EQUIL S-METHOPRENE 1.2% IGR CONCENTRATE 

EPA Receipt Date: 18-Nov-20lO 

EPA Company Nmnber: 87276 

Company Name: ENVINCIO LLC 

JANELLE KAY 

PYXIS REGULATORY CONSULTING, INC. 

ENVINCIO LLC 

4110 1136TH STREET, NW 

GIG HARBOR, WA 98332-

SUBJECT: Receipt of Registration Application Subject to Registration Service Fee 

Dear Registrant: 

The Office of Pesticide Programs has received your application and certification of 

payment. If you submitted data with this application, the results of the PRN-86-5 screen will be 

communicated separately. During the administrative screen, the Office of Pesticide Programs 

has determined that this Action is subject to a Pesticide Registration Service Fee as defined in 

the Pesticide Registration Improvement Act. 

The Action has been identified as Action Code: B660 

ME-TOO;NEW PRODUCT;MICROBIALIBIOCHEMICAL;F AST-TRACK; 

No additional payment is due at this time. We will process a refund of your $275 

overpayment as soon as is practicable. 

If you have any questions, please contact the Pesticide Registration Service Fee 

Ombudsman at (703) 305-7973. 

SinCerelY'~~~Uxz-.... Front End Processing Staff 

Information Technology & Resources Management Division 
125

IFee for Servicel 

This package includes the following 

@ New Registration 

°Amendment 

o Fee Waiver? 

for Division 

OAD 

@BPPD 

oRO 

{8859471-

! 

I 0 volpay % Reduction: 

Risk Mgr. []]] 

Receipt No. s-I 885947 l 

EPA File Symbol/Reg. No. 1 87276-T 

I Pin-Punch Date: 1 11/18/2010 L _________________________________ _ 

n This item is NOT subject to FFS action. 

-' 

Action Cude: --:1 Parent/Child Decisions: ! 

I ! i 

Requested: I R300 II I 

II 

Granted: I ~C~ 0 !' 

'-----_A_m __ ou_n_t _Du_e_: _$_a_, ___ II_t;_i ___ \IL! ____________ ~ 

Uncleared Inert in Product 
126
127

FEE FOR SERVICE 
128

Mike Kellogg 

From: 

Sent: 

To: 

paygovadmin@mail.doc.twai.gov 

Wednesday, November 17,20108:09 AM 

Mike Kellogg 

Subject: Pay.Gov Payment Confirmation 

THIS IS AN AUTOMATED MESSAGE. PLEASE DO NOT REPLY. 

Your transaction has been successfully completed. 

Transaction Summary 

Application Name: PRIA Service Fees 

Pay.gov Tracking 1D: 251TK7JU 

Agency Tracking 1D: 74152812159 

Account Holder Name: Randall V Canady 

Transaction Type: Sale 

Transaction Amount: $1,434.08 

Billing Address: 200 Cascade Point Lane, Ste 181 

City: Cary 

State/Province: NC 

Zip/Postal Code: 27513 

country; USA 

Card Type: American Express 

Card Number: ***********1809 

Transaction Date: Nov 17, 2018 11:89:21 AM 

Decision Number: 

Registration Number: 87276-xx 

Company Name: Envincio LLC 

Company Number: B7276 

Action Code: R300 

1 

, , , 3 , , , 

, '" , 

, , , " 

'" , 
129

Pf •••• f. d rrutructJ, • /Ufo,. , n m '0 Fo A< rov8d . 'IB No. 2070'()()8C I.ml," 2·28·95 

United StetoB ~ Registration OPP Identifier Number 

&EPA Environmental Protection Agency Amendment Wa~hington, DC 20460 Other 

Application for Pesticide - Section I 

t. Company/Product Number 2. EPA Product Manegor 3. Proposod Clessificotion 

87276· "/ L. Hollis [{-J None o Restrictod 

4. CompenylProduct tNamol PM. 

Envincio LLC I Equil S-Mathoprana 1.2% IGR Concentrale 91 

5. Name and Addross of Applicant flnc/ud. ZIP Code) 6. Expedited Reveiw. In accordance with FIFRA Section 3(c[(3) 

Envincio LLC Ibj[i[, my product is similar Ot identical in composition and labeling 

c/o Pyxis Regulatory Consulting, Inc. to: 2724-352 4110 136thSt. NW EPA Reg. No. 

Gia Harbor. WA 98332 o Chock ff thrs j$ a nll'W addfoss Product Name 

Zoecon RF-291 Emulsifiable Concentrale wilh Precor 

Section - II 

0 Amendment - Explain balow. U Final printed labels in ropoonse to 

Agancy letter dotod 

0 Resubmission in responii1e to Agency letter dated [2] "Me Too" Applicotion. 

0 Notificelion - Explain below. 0 Other - Explein below. 

Explanation: Uso addilional pagotsl if necossory. IFor $sction I and Seclion 11.1 

This application falls under Category R300 (44) as it is a new product substantially similar in composition and use to a registered product, 

only product chemistry data are being submitted and the cile-all method of data support is being used to support product specific acute 

toxicity and efficacy data requirements. The fee due is $1434.00 and the decision timeline is 3 months. A receipt of PRIA pre-payment from 

pay.gov is included with this application, Should you have any questions, please contact me at (email) Mike@PyxisRC.com or (phone) 253-

853-7369, 

Section· III 

1. Materi.1 Thia Pr.duct Wi" Be Pack.gad In: 

Child-ResiSlont Pockeging Unil P&ck&ging Woter Solubla Packaging 2. Type of Conteiner 

t2]y" ~y" B y" [;J M".I 

.( No .( No No 

./ Plootic 

Gleys 

• Certification must If "Yosft No. per If ·Yesft No. per Papor 

Unit Pockeging wgl. container Pockoge wgt containor Other (Specifyl be submitttHJ 1 oz. 10 

3. Localion of Net Contants Information 4. Size(s) ROlail Container 15. Locetion of label Oiroctions 

J - On Labol [{J Lebel [{J Container 10x1fLoz.and16n. 0'. ~ On Lab~ling ace<>mpanylng producl 

6. Mannor in Which Lebel is Affixed to Product lJ Uthogreph 0 Other 

./ paper ~Iued Stenei ed 

Section - IV 

1. Contact Point (Camp/uta irams difacr/y btl/ow for idanrfficarion of fndfvfdulll to ba contactfld, if nucflssflry. ro procass this flPp/{cati<J1lo) , ... Name Titlo Telephone No! (Jnclude Aroo Codel 

Michael Kellogg Agent (253) 853·1;000:, 

Certification " , , , - 6. Deto4Applicetion • , , I cortify th&t tho statemants I have made on this form and 011 attachmenls tharato ero true, eccurote ond complote.' Aeclriv:td 

'''» >, locknowlodge that any knowlinglly felse or misleading slotemont mey bo punishabla by fino or imprisonmon~ co' ' , , (Stamped) both under applicobla low. ' , .. , , , 

2'S;;~jj j{) ~ 3. Title " " ) .. , , .. • 

Agent , " , , " 

4. Typed Nome /' // S.Ooto ,)' ; 

, Michael Kellogg 

11117(tO ") , 

.. EPA Form 8570-' (R.v. 3·941 PravlOus odlllons oro obsolote . Whit. - EPA Fi~ Copy (anginal) Yallow - Applicant Copy 
130

Py], iREGULATORY CONSULTINl :NC. 

4110 136th St. NW 

Gig Harbor, WA 98332 

COURIER DELIVERY 

Linda Hollis (PM 91) 

Document Processing Desk (REGFEE) 

Office of Pesticide Programs (7504P) 

U.S. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 S. Crystal Drive 

Arlington, VA 22202-450 I 

November 17,2010 

Phone: 253~853-7369 

Fax: 253-853-5516 

www.PyxisRC.com 

RE: Envincio LLC ~ Equii S-Methoprene 1.2% IGR Concentrate (EPA Reg. No. 87276- ) 

Application for a New Pesticide Registration 

Dear Ms. Hollis, 

On behalf of Envinca LLC please find the enclosed application materials for registration of Equil sMethoprene 1.2% IGR Concentrate an end-use product containing S-methoprene as the active ingredient. 

In support of this application, we submit the following documents: 

I. Application for a New Pesticide Registration (EPA Form 8570~1) 

2. Receipt ofPRIA pre-payment from pay.gov 

3. Confidential Statements of Fonnula (Basic and three (3) Alternate Formulations dated November 

2,2010) 

4. Fonnulators Exemption Statement (EPA Form 8570-27) 

5. Five (5) copies of the proposed labeling 

6. Certification With Respect to Label Integrity 

7. Electronic copy of the proposed label on CD 

8. Certification with Respect to Citation of Data (EPA Form 8570-34) 

9. Agency Internal Use Copy of the Data Matrix (EPA Fonn 8570-35) 

10. Public File Copy of the Data Matrix (EPA Fonn 8570-35) 

II. Letter of Authorization 

12. Product Specific Data: 

Volume I 830.1550,830.1600, Miller, R. Product Identity and Composition, Descriptior~ ofM<'!terials 

830.1650,830.1670, Used to Produce the Product, Description ofthe Fonnula:ion Process, 

and Discussion ofFonnation oflmpurities. -- Volume 2 830.1700, 830.1750, Miller, R. Equil S-Methoprene 1.2% IGR c:onq::ntrate Pr.>!;LnilJbJ), 

830.1800 Analysis, Certified Limits and Enforcement A,Jaly.ical Methorls. 

Volume 3 830.6302 through Miller, R. (S)-Methoprene IGR EC Product CJ.tnl!$try. Pl'o'duct 

830.7950 Properties: Color, Physical State, Odor, OXlUatlOn/Reduction: 

Chemical Incompatibility, Flammability, pH, Viscosity, en::! D6csity. 

Equil S-Methoprene 1.2% IGR Concentrate is substantially similar to the currently registered pcuJuct 

(EPA Reg. No. 2724-352). Envincio LLC believes this application falls under Category R300 (44) since 
131

L. Hollis 

November 17, 2010 

Page 2 of2 

Equil S-Methoprene 1.2% IGR Concentrate is a new product, substantially similar in composition and use 

to a registered product, only product chemistry data are being submitted to support the application for 

registration and the cite-all option under the selective method is being used to support product specific 

acute toxicity and efficacy data requirements. In addition, the technical source(s) of active ingredient are 

based on registered source(s) of supply and therefore, Equil S-Methoprene 1.2% lOR Concentrate 

qualifies for FOITIlulators Exemption for S-methoprene generic data requirements. 

Please note: (S)-Methoprene IGR EC and Equil S-Methoprene 1.2% lOR Concentrate are the same 

product. Envincio requested the product name be changed to Equil S-Methoprene 1.2% IGR Concentrate 

shortly before submitting this application for registration. 

We trust you will find this application complete and in compliance with the requirements for registration 

under FIFRA. Please feel free to call me if you have any questions or need any additional infonnation. 

Michael Kellogg 

Enclosures 
132

There is an ELECTRONIC LABEL for this action 

You can use Acrobat to compare the e-Iabel to the previous version (and find the 

changes). You can also use Acrobat to mark-up the e-Iabel with your comments. 

If e-Iabel was submitted via 

CD-ROM with paper application 

then you will find e-Iabel in 

Electronic Label Library 

If 1110 o-Iohol is nol found in /110 ELL IIlen il WllS probobly no/ nomed 

correcl/y end could no/II(! onterod 1/110 Ilia ELL. However, !lIO filo 

can be relrievad rro,!2J!!g~CD which is retained by /flO F!...onl Enrj, __ 

or If e-Iabel was submitted via 

XML E-Submission (no paper) 

then you will find e-Iabel in 

Documentum 

See overview of processing e-Iabels on other side of this sheet. 

If you have any questions on e-Iabels. please contact one of your division e-Iabel experts: 

AD Willie Abney 308-1689 

Renae Whitaker 308-7003 

Tracy Lantz 308-6415 

BPPD 

RD Tom Harris 308-9423 
133

1 

t 

; 

I""KU\,;t:~~IN\,:j t:Lt:(; I KUNI(; LABeLS 

(rev, 115109, tch) 

If e-Iabel submitted via XML e-submission (not on CD-ROM), you may wish to find e-Iabel in 

Documentum, save e-Iabel to "My Documents", add e-Iabel to ELL, start below at step 5, 

Initial E-Label per application (on CD-ROM with paper via ITRMD) 

1 ITRMD receives , Tracking J ITRMD adds r, ITRMD sends ~ Connect ELL 

paper submission record added to e-Iabel to ELL paper submission record with 

wI e-Iabel on CD OPPIN to AD/BPPD/RD OPPIN S# 

in-process 

\j Save copy of e- I Review label II Add comments !J Print annotated elabel from ELL to to e-Iabel label 

My Documents III OCC~p,"bltl, .kJp 10 .Iup ZO) (n,o, u:I:1 '\vllh 

'Om,nQ~I." 10 hiaMmo (u.e 'p, I~t wilh rJtn",nu") 

review 

11.1 Send annotated 11 File print of !< Add annotated e" Ll Close 

e·label to registrant annotated e"label label to ELL submiSsio)l in 

via email and email in jacket OPPIN 

(~I," ,o"d "Ho~' To p),""1 

out-process 

Resubmission (via email to staffer or PM) 

!4 Receive email 1~ Add tracking If .. Add e"label 

submission wI e· record to to ELL 

label allacl1ed OPPIN 

in~process 

,II Save copy of e" lU Compare old and 

labels {old & new) from new labels with 

ELL 10 My Documents Acrobat 

:11.1 Print e.label, 0'1 Mail stamped 

stamp, write cover label & cover 

leller letter to registrant 

(u.e "P"n', \\llh r"o"mnU'1 

process - big picture 

1- create OPPIN tracking 

2- put label in ELL; link to S# 

3- save ELL label to My Documents 

4- compare / comment 

5- outprocess 

review 

'U File stamped 

label & cover letter 

in jacket 

oul-process 

11 Connect ELL 

record with 

OPPIN Sft 

(if revisions needed repeat steps 8-19) 

~J Add cover ~·1 Close 

leiter to ELL submission in 

(",,,"",,10<), J ~,.cu~'"~ OPPIN w,!t. cun,mu,,'~) 

techniques to know 

- filename for e-Iabels 

• "print with filename" 

• compare / comment 

- printing with comments 
134

Applicant's Name and Address 

Envincio LLC 

200 Cascade Point Lane, Suite 101 

Cary, NC 27513 

Form approved. OMS No. 2070-0060, 2070-0057, 2 ... , ,-,-01 07, 2070-0122, 2070-0164. 

United States 

Environmental Protection Agency 

Washington, DC 20460 

Formulator's Exemption Statement 

(40 CFR 152.85) 

EPA File Symbol/Registration Number 

87276-

Product Name 

Equil S~Methoprene 1.2% IGR Concentrate 

Dale of Confidential Statement of Formula (EPA Fonn 8570-4) 

11/02/2010 

t; i I 

(1) This product conlains the following active ingredient{s): 

S~Methoprene 

(2) Ot Ihese. each active ingredient listed in paragraph (4) is present solely as the result of the use of that active ingredient in the manufacturing, 

formula lion or repackaging another product which contains that active ingredienl which is registered under FIFRA Section 3. is purchased by 

us from anolher person and meets the requiremenls of 40 CFR section 158.50{e){2) or (3). 

(3) Indicale by checking (A) or (B) below which paragraph applies: 

11 (A) An accvrate Confidential Stalement of Formula (EPA FORM 8570-4) for Ihe above identified product is allached 10 thiS statement. 

That formula stalement indicates, by company name, registration number, and product name, the source of the aclive ingredienl{s) lisled in 

paragraph (1). 

OR 

"I (B) The Confidential Stalemenl of Formula (CSF){EPA Form 8570-4) referenced above and on file wilh Ihe EPA is complete, current, an 

accurate and conlains the information required on the current CSF. 

(4) The following active ingredients in this product qualify for the formulator's exemption. 

S~Methoprene 

Source 

it 

Michael 

, 

" 

'" , 

- Applicant copy 

*Product ingredient source information may be entitled to confidential treatment*
135

Form Approved OMS No. 2070-0060 

"~"". UNITED STATES ENVIRONMENTAL PROTECTION AGENCY ~Al ~, 401 M Street, S.W. - WASHINGTON, D,C. 20460 

Paperwork Reduction Act Notice: The pubic reporting burden for this collection of information is estimated to average 1.25 hours per response for registration 

and 025 hours per response for reregistration and spedal review activities, including time for reading the instructions and completing the necessary forms. Send 

comments regarding bmlen estimate or any other aspect Of this collection of information, including suggestions for reducing the burden to: Director. QPPE 

Information Management Division (2137), U,S. En,,;ronmental Protection Agency, 401 M Street, S.w., Washington, DC 20460. 

00 not send the completed form to this address. 

Cert!flcation with Respect to Citation of Data 

Applicanfs/Registranfs Name, Address, and Telephone Number EPA Registration Number/File Svmbol 

Envincio LLC cio Pyxis Regulatory Consull;ng, Inc.; 4110 136th SI. NW Gig Harbor. WA 96332. (253) 653-7369 87276-

Active Inqredient(s) and/or representative test comoound(s) Date 

S-methoprene November 17, 2010 

General Use Pattem(s) (list al those claimed for this product using 40 CFR Part 158) Product Name 

Terrestrial Nonfood; Indoor Use Equil S"Methoprene 1.2% IGR Concentrate 

NOTE: If your product is a tOO% repackaging of another purchased EPA-registered product labeled for all the same uses on your label, you do not need to 

submit this form. You must subm~ the Formulato~s Exel"llJtion Statement (EPA Form 8570-27). 

0 I am responding to a Data-Call-In Notice, and have induded with this form a list of companies sent offers of compensation (the Data Matrix form shoukj 

be used for this purpose). 

SECTION t: METHOD OF DATASUPPORT (Check one method only) 

0 I am using the dte-all method of support, and have included with this form [2] I am using the selective method of support (or cite-all option 

a list ot companies sent offers of compensation {the Data Matrix form under the selective method}, and have indLlded with this form a 

should be used for this purpose). completed list of data requirements (the Data Matrix form must be 

used). 

SECTION It: GENERAL OFFER TO PAY 

IRequired if using the c~e-all method or when using the cite-all option under the selective method to satisfy one or more data requirementsl 

[2] I hereby offer and agree to pay compensation, to other persons, with regard to the approval of this applicatton, to the extent required by FIFRA. 

SECTtON ItI: CERTIFtCATlON 

I certify that this application for registration, this form for reregistration, Cf'this Data-CalHn response is supported by all data submitted or cited in the 

application for registration, the form for reregistration, or the Oata-Call-In response, b1 add~ion, if the cite-all option or dte-all opUon under the selective method is 

indicated in Section I, this application is supported by al data in the Agency's files that (1) concem the properties or effects of this product or an identical or 

substantially similar product, or one or more of the ingredients in this produd: and (2) is a type of data that would be required to be submitted under the data 

requirements in effect on the date of approval of this application if the application sought the initiat registration of a product of identical or similar composition and 

uses. 

I certify that for eam exdusive use study died J1 support of this registraUon or reregistration, Illat I am the original data submitter or thilt I ha'{e obtained 

the written permission ofthe original data submilterto c~e that study. , """. 

I certify that for each study c~ed in support ofthrs registration or reregistration that is not an exdusive use study, either: (a) I am the OIlpjf18! q'lja 

submitter; (b) I have obtained the permission of Ille original data subm~ter to use the study in support of this application; (c) all periods of eligibil:ly for 

compensation have expired for the study: (d) the study is in the public literature: oriel I have notified in writing the company tha~~lJ\J'J11t'7d the study Wld have 

offered (I) to pay compensa~on to the extoot required by sections 3{c}(I}(F) and/or 3{c}{2XB) of FIFRA; and (Ii) to commence nllgotiatio,1s to determine the 

amount and terms of compensation, if any, to be pai:l for the use of the study. ' , ~ , ~ , ; • ;, > , , " , , , I certify that in all instances where an offer of compensation is required. copies of all olfers to pay compensation and evidcn;e of their d$l);{el'i' in 

accordance with sections 3(c)(1 }(F) and/or 3(c}(2}(B} of FIFRA are available and will be submitted to the Agency upon request., ~iJ('Jj.d t tail to Pr:l~-u'bJ ~uch 

~:~~ to the Agency upon request, I understand that the Agency may initiate action to deny, cancel or suspend the registrati9n, '1 Illy-product in col'formity with 

, , " , , .. I certify that the statements t have matle on this form anti at! attachments to It are !rue, accurae, anti complete. I acknowlldge that any 

knowingty fatse or misteadlrg statement may be punishable bJ fine or imprisonment or both under applicatllo law. ) , , , , , , , > , 

S~A'j;d~. D;;'lnuo Typed or Printed Name and Title 

Micheel Kellogg; Agent 

EPA Form 8570-34 (9-97) Electronic per versions available. Submit only Paper version. 
136

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

401 M Street, S.W. 

WASHINGTON, D.C. 20460 

Paperwork Roduction Act Notice: The public reporting burden for this collection of information is estimated to average 0.25 hours per response for registration activities and 0.2

reregistration and special review activities. including time for reading the instruclions and completing the necessary forms. Send comments regarding the burden estimate or any oinformation, including suggestions for reducing Ihe burden 10: Director, OPPE tnfomlation Management Division (2137), U.S. Environmental Protection Agency, 401 M Street. S.W

send the fOmlto this address. 

DATA MATRIX 

Oate November 17, 2010 

ApplicanfslRegistranl's Name & Address 

Ingredient S-Melhoprene 

Envincio LLC 

200 Cascade Point Lane, Suite 101 

Cary, NC 27513 

Guideline Reference Number I Guideline 

Product Specific Data Requirements 

830.1550 I Product Identity and Composition 

830.1600 Description of Materials Used to Produce the 

Product 

830.1620 1 Description of Production Process 830.1650 I Desc..r:!m.ion of Formulation Process 

830.1670 I Discussion of Formation of Impurities 830.1700 I Preliminary Analysis 830.1750 I Certified limits 

MRID Number 

Volume 1 Volume 1 

Volume 1 Volume 1 Volume 2 

830.1800 I Enforcement Analytical Method I vUlume L 

830.6302 Color I ... vOlume .j 

"_L ___ . 830.6303 Physical State I VUIUIIII;:l 0 

830.6304 O!::lor 

, , 

830.6313 §tability to Normal and Elevated Temperatures, 

Metals, and Metal Ions 

Volume 3 

EPA Reg No.fFile Symbol 87276- Product 

Equil S-Methoprene 1

Submiller 

Envincio LLC Envincio LLC 

Envincio LLC 

Envincio LLC 

Envincio LLC 

Envincio LLC 

Envincio LLC Envincio LLC 

Envincio LLC 

1830.6314 __ , __ "'----' Chem·lcallncompatibility Volume 3 Envincio LLC 

830.6315 Flamp,abinty Volume 3 Envincio LLC 830.6316 

Signature Name and Tille 

Michael Kellogg, Consultant 

EPA Form 8570·35 and Paper versions available. Submil only Paper version_ Agency tn
137

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

401 M Street, S.W. 

WASHINGTON, D.C. 20460 

PapelWork Reduction Act Nottce: The pub tic reporting burden for this coltection of intormation is estimated to average 0.25 hours per response for registration activities and 0.2

reregistration and special review actMties. including time for reading the instructions and completing the necessary torms. Send comments regarding the burden estimate or any 

intormation, including suggestions for reducing the burden to: Director, OPPE Intormation Management Division (2137), U.S. Environmental Protection Agency, 401 M Street, S.W

send the form to this address. 

DATA MATRIX 

Date November 17, 2010 EPA Reg NO./File Symbol 87276- 

Applicant's/Registrant's Name & Address Product 

Envincio LLC Equil S-Methoprene 1

200 Cascade Point Lane, Suite 101 

Cary, NC 27513 

Inaredient S-MelhoDrene 

Guideline Reference Number Guideline Stu_I!:i.Name MRID Number SubmiUer 

830.6317 Storaqe Stability 

830,6319 Miscibility 

830,6320 Corrosion Characteristics 

830.6321 Dielectric Breakdown Voltage 

830,7000 pH Volume 3 Envincio LLC 830,7050 UVNisible Absorption 

830.7100 Viscosity Volume 3 Envincio LLC 

830,7200 Melting PoinUMelting Range 830,7220 Boiling PoinUBoiling Range 830,7300 Densitv/Relative DensitvlBulk Densitv Volume 3 Envincio LLC 

830,7370 Dissociation Constants in Water 

830.7520 Particle size, fiber length, diameter distribution 

830,7550 Partition Coefficient (n-octanol/water), Shake 

Flask Method 

830,7560 Partition Coefficient (n-octanol/water), 

Generator Column Method 

830,7570 Partition Coefficient (n-octanol/water), 

Estimation by Liquid Chromatography 

j/J Name and Title 

Michael Kellogg, Consultant 

,gency 
138

! 

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

401 M Street, S.W. 

WASHINGTON, D.C. 20460 

Paperwork Reduction Act Notice: The public reporting burden for this collection of information is estimated to average 0.25 hours per response for registration activities and 0.2

reregistration and special reView actillities, including lime for reading fhe instructions and completing the necessary forms. Send comments regarding the burden esfimate or aoy 

in/onna/ion, including suggestions for reducing the burden 10: Director, OPPE lolorma/ion Management Division (2137), U.S. Environmental Protection Agency, 401 M Street, S.W 

send fhe fonn to this address. 

DATA MATRIX 

Oafe November 17, 2010 EPA Reg No.lFile Symbol 87276- 

Applicanf's/Regisfranf's Name & Address Product 

Envincio LLC Equil S-Methoprene 

200 Cascade Point Lane, Suite 101 

Cary, NC 27513 

Ingredienl S-Methoprene 

Guideline Reference Number Guideline Sfudy Name MRID Number Submitter 

830.7840 Water Solubility: Column Elution Method; 

Shake Flask Method 

830.7860 Water Solubility, Generator Column Method 830.7950 Vapor Pressure 

870.1100 Acute Oral TOXicity: Rat Cite-All 870.1200 Acute Dermal Toxicity: Rat Cite-All 870.1300 Acute Inhalation Toxicity: Rat Cite-All 

8702400 PrimarY Eye Irritation: Rabbit Cite-All 

870.2500 Primary Dermal Irritation Cite-All 

870.2600 Dermal Sensitization Cite-All 

810.3500 Premises Treatments Cite-All 

Sigo"", jiJ A1Jh Name and nile 

4t/.; -" Michael Kellogg, Consultant c-- 

/u 

EPA Form 8570-35 (9-97) Eleclfonic and Paper lIersions allailable. Submit only Paper lIersion. Agency I
139

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

401 M Street, S.W. 

WASHINGTON, D.C. 20460 

Paperwork Reduction Act Notice: The public reporting burden tor this collection of informalion is eslimaled to average 0.25 hours per response tor regislration activities and 0.2

reregistration and special review aclivilies, including time for reading the instructions and completing the necessary forms. Send commenls regarding the burden eslimate or any 

informalion, including suggestions for reducing the burden to: Oirector, OPPE Informalion Management Division (2137). U.S. Environmenlal proteclion AgenCy, 40t M Street, S_W 

send the form to this address. 

DATA MATRIX 

Oale November 17, 2010 EPA Reg No.fFile Symbol 87276- 

Applicanl's/Registranl's Name & Address Product 

Envincio llC Equil S-Methoprene 1

200 Cascade Point lane, Suite 101 

Cary, NC 27513 

Ingredienl S-Melhoprene 

Guideline Reference Number Guideline Study Name MRID Number Submitter 

Equll S-Methoprene 1.2% IGR Concentrate Product Specific Data Requirements 

Envincio llC is using the cite-all option under the selective method to satisfy 

acute toxicity and efficacy data requirements. Envincio llC will make offers-topay to the following companies on the September 30, 20 to Data Submitters list 

for S-Methoprene. 

S-Methoprene product Specific Data Requirements 

S-Methoprene Product Cite-All ADM Alliance Nutrition, Inc. 

Specific Data Requirements S-Methoprene Product Cite-All Sergeant's Pet Care Products, Specific Data Regyirements Inc. 

S-Methoprene Product Cite-All The Hartz Mountain Corp. 

Data Requirements 

S-Methoprene Product Cite-All Wellmark International 

Specific Data Requirements 

S-Methoprene Product Cite-All Chattem, Inc. 

Specific Data Requirements 

S-Methoprene Product Cite-All ZEP Commercial Sales & 

Specific Data Regyirements Service 

Sigo"ore I. t] Name and Tille 

/>/i.- Michael Kellogg, Consultant /, 

EPA Form 8570-35 (9-97) Electronic and Paper versions available. Submit only Paper version. Agency I
140

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

401 M Street, S.W. 

WASHINGTON, D.C. 20460 

Paperwork Reduction Act Notice: The public reporting burden for this collection ot illfonnation is estimated to average 0.25 hours per response for registration activilies and 0.2

reregistrntion and special review aclivities, including time for reading the inslructions and completing the necessary fonns. Send comments regarding the burden estimate or any o

infonnation, including suggestions for reducing the burden to: Oirector, OPPE Information Management Oivision (2137), U.S. Environmental Protection Agency, 401 M Street, S.W

send the fonn to this address. 

DATA MATRIX 

Oate November 17, 2010 EPA Reg No.lFile Symbol 87276- 

Applicanl's/Registrant's Name & Address Product 

Envincio LLC Equil S-Methoprene 1

200 Cascade Point Lane, Suite 101 

Cary, NC 27513 

Inqredienl S-Melhoorene 

Guideline Reference Number Guideline Stud Name MRID Number Submiller 

S-Methoprene Product Cite-All Control Solutions, Inc. Specific Data Requirements 

S-Methoprene Product Cite-All Management Contract 

Specific Data Requirements Services, Inc. 

S-Methoprene Product Cite-AI! Mertal Limited 

Specific Data Requirements S-Methoprene Product Cite-All Spray Drift Task Force 

Specific Data Requirements S-Methoprene Product Cite-All B2E Corporation 

$peclfic Data Requirements 

S-Methoprene Product Cite-All Bablona Bioenvironmental 

Specific Data Requirements Centre Ltd. 

S-Methoprene Product Cite-All Egis Pharmaceuticals Public 

Specific Data Requirements Limited Co. 

S-Methoprene Product Cite-All Valent BioSciences 

$pecific Data Requirements Corporation 

S-Methoprene Product Cite-AI! Ambrands 

Specific Data Requirements 

Name .md Tille 

Michael Kellogg, Consultant 

EPA Fonn 8570-35 (9-97) Eleclronic and Paper versions available. Submil only Paper version. Agency tn
141

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

401 M Street, S.W. 

WASHINGTON, D.C. 20460 

Paperwork Reduction Act Notice: The public reporting burden for this collection 01 information is estimated to average 0.25 hours per response for registration activities and 0.2

reregistration and special review activities, including time for reading the instructions and completing the necessary forms. Send comments regarding the burden estimate or any o

information, including suggestions for reducing the burden to: Director, OPPE Information Management Division (2137), U.S. Environmental Protection Agency, 401 M Street, S.W 

send the form to this address. 

DATA MATRIX 

Date November 17,2010 EPA Reg No.lFile Symbol 87276- 

Applicant's/Registrant's Name & Address Product 

Envincio LLC Equil S-Methoprene 1

200 Cascade Point Lane, Suite 101 

Cary, NC 27513 

Innredienl S-Methonrene 

Guideline Reference Number Guideline Studv Name MRIDNumber Submitter 

S-Methoprene Product Cite-All Marketquest, Inc. 

Specific Data Renuirements 

S-Methoprene Product Snecific Data 

Cite-All Hartz-B2E LLC 

S-Methoprene Product Cite-All Joint 

Soecific Data Reauirements Venture REJV 

S-Methoprene Product Cite-All B2E Biotech LLC 

Snecific Data Renuirements 

S-Methoprene Product 

Snecific Data 

Cite-All Zocor Incorporated 

S-Methoprene Product Loradochem, Inc. 

Snecific Data Renuirements 

Generic Data Renuirements 

Equil S-Methoprene 1.2% IGR Concentrate qualifies for Formulator's Exemption for SMethoorene aeneric data reauirements. 

Sig"",re L /J, Name and Title 

/A - Michael Kellogg, Consultant 

EPA Form 8570-35 (9-97) Electronic and Paper versions available. Submit only Paper version. Agency In
142

Endnotes for Data Matrix for Equil S-Methoprene 1.2% IGR Concentrate 

1830.1620 _ Per QPPTS 830.1000, these data are not required for the registration of an 

end-use product. See 830.1650 for formulation process information. 

2830.1700 _ This product does not consist solely of the technical grade active ingredient (TGAI) and is 

not produced by an integrated system, therefore, per OPPTS 830.1700, these data are not required. 

, 830.6313. 830.7050. 830.7200. 830.7220. 830.7370. 830.7550. 830.7560. 830.7570. 830.7840, 

830.7860 and 830.7950 - Per OPPTS 830.1000, these data are not required for the registration of an 

end-use product. 

4830.6316 _ This product does not have explosive characteristics; therefore these data are not required. 

Please refer to the Confidential Statement of Formula for additional information on the composition of 

Equil S~Methoprene 1.2% IGR Concentrate. 

s 830.6317, 830.6320 - Envincio LLC is currently conducting storage stability and corrosion characteristic 

studies to satisfy guidelines 830.6317 and 830.6320, respectively. Per PR Notice 92·5, storage 

stability data are not required to be submitted unless specificaJly requested by the Agency. QPPTS 

830.6317 and 830.6320 guidelines alJow the corrosion characteristics study and storage stability study 

to be conducted simultaneously. Envincio LLC wilJ submit these data upon completion. As these 

studies take over a year to complete, Envincio LLC requests that a conditional registration for Equil S~ 

Methoprene 1.2% IGR Concentrate be granted on the submission of these data. 

6830.6319 - The Equil S~Methoprene 1.2% IGR Concentrate proposed labeling recommends dilution 

with water, not oil; therefore, these data are not required. 

7830.6321 - This product is not proposed for use around electrical equipment. Therefore, these data are 

not applicable nor are these date required. 

8 830.7520 ~ These data are not required for Equil S~Methoprene 1.2% IGR Concentrate because it is not 

water insoluble and is not a fibrous material. 

Page 1 of 1 
143

Certification with Respect to Label Integrity 

version: 9111/02 

I certify that the information (including, but not limited to, text, tables, and graphics) 

contained in the electronic file identified below by file name and submitted with this 

certification is the same information as that on the paper copies of these documents 

included with this submission. 

IPROPOSED LABEL 

Date Submitted 

EPA Registration # to EPA Electronic file name 

87276-xx November 17,2010 087276-xxxxx.201 01117. Equil S-Methoprene 

1.2% lOR Concentrate label.pdf 

I certify that the statements that I have made on this form are true, accurate, and 

complete. I acknowledge that any knowingly false or misleading statements may be 

punishable by fine or imprisonment or both under applicable law. 

Signature Date 

Michael Kellogg 

Name (typed) , , , , , > 

Agent , , , , , , 

Title 

. " ". , 

• " " 

, " , , , 

'" , ", , 
144

])eccmber 3, 20()9 

To Whom It May Concern: 

RE: LeHer of Authorization 

Dcar Sir or lVladam: 

E"villcio LLC 

200 Cascade Pointe Lane, Su ire 101 

Cary, North Carolina 27513 

919-610-1065 

919-677·6161 (Fax) 

Please let this letter serve to confirm that Pyxis Regulatory Consulting, Il1c. is authorized to act as agents 

(or Envincio LLC (EPA Company Nllmber [pendingj), before the U.S, Environmental Protection Agency 

and stale governmental agcltcics in all matters regarding our pesticide registrations pursuant to the Fcdcrnl 

Insecticide, Fungicide and Rodenticide Act("FlFRA"), 7 U.S.C. § 136 et seq. and St'dtc law. 

lfyotl have any quc!itions. please do not hesitate to contact me. 

Sincerely. 

~y~ Randall V. Canady 

Founder & Chief Executive Officer 

cc: Pyxis Regulatory COI1Sllltiltg. Il1c. 

,,' . 

" , , , 

" , 

"" , 
145

PR,FORM _ ..... SOU 

FU.ESYMBOL 

REC1STRATION NO. 

87:r16-T 

CONFIDENTIAL STATEMENT OF FORMULA ENC

DATE 

SUBMITTED 

NOV 18 2010 

. 

SUBMITTED BY (,;) 

APPLICANT BASIC SUPPLIER Do Not Write Com

Formula, or Parts of 

on This Envelo

NOTE 

It sball be untawful-for any person to use 

Of to reveal, other than to the Secretaf%. or 

the United States Department of Agriculture o

or to the courts In response to a subpoena, 

emergencies to pharmacists and other qual

the preparation of antidotes, In accordance the Secretary may prescribe, any Informatio

products acquired by authority of Section 4 of 

fungicide. and Rodenticide Act. " 
Pages 146-159-*Confidential Statement of Formula may be entitled to co