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                                                                   EXHIBIT 10.13


                      STRESSGEN BIOTECHNOLOGIES CORPORATION
                           2001 EQUITY INCENTIVE PLAN

                            STOCK OPTION AGREEMENT S
           (INCENTIVE OR NONSTATUTORY WITH ACCELERATION AND PARACHUTE)


Pursuant to your Stock Option Grant Notice ("Grant Notice") and this Stock
Option Agreement, Stressgen Biotechnologies Corporation (the "Company") has
granted you an option under its 2001 Equity Incentive Plan (the "Plan") to
purchase the number of shares of the Company's Common Stock indicated in your
Grant Notice at the exercise price indicated in your Grant Notice. Defined terms
not explicitly defined in this Stock Option Agreement but defined in the Plan
shall have the same definitions as in the Plan.

The details of your option are as follows:

         1.       VESTING. Subject to the limitations contained herein, your
option will vest as provided in your Grant Notice, provided that vesting will
cease upon the termination of your Continuous Service.

         2.       NUMBER OF SHARES AND EXERCISE PRICE. The number of shares of
Common Stock subject to your option and your exercise price per share referenced
in your Grant Notice may be adjusted from time to time for Capitalization
Adjustments, as provided in the Plan.

         3.       METHOD OF PAYMENT. Payment of the exercise price is due in
full upon exercise of all or any part of your option. You may elect to make
payment of the exercise price in cash or by check or in any other manner
PERMITTED BY YOUR GRANT NOTICE, which may include one or more of the following:

         (a)      In the Company's sole discretion at the time your option is
                  exercised and provided that at the time of exercise the Common
                  Stock is publicly traded and quoted regularly in THE WALL
                  STREET JOURNAL, pursuant to a program developed under
                  Regulation T as promulgated by the Federal Reserve Board that,
                  prior to the issuance of Common Stock, results in either the
                  receipt of cash (or check) by the Company or the receipt of
                  irrevocable instructions to pay the aggregate exercise price
                  to the Company from the sales proceeds.

         (b)      Provided that at the time of exercise the Common Stock is
                  publicly traded and quoted regularly in THE WALL STREET
                  JOURNAL, by delivery of already-owned shares of Common Stock
                  either that you have held for the period required to avoid a
                  charge to the Company's reported earnings (generally six
                  months) or that you did not acquire, directly or indirectly
                  from the Company, that are owned free and clear of any liens,
                  claims, encumbrances or security interests, and that are
                  valued at Fair Market Value on the date of exercise.
                  "Delivery" for these purposes, in the sole discretion of the
                  Company at the time you exercise your option, shall include
                  delivery to the Company


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                  of your attestation of ownership of such shares of Common
                  Stock in a form approved by the Company. Notwithstanding the
                  foregoing, you may not exercise your option by tender to the
                  Company of Common Stock to the extent such tender would
                  violate the provisions of any law, regulation or agreement
                  restricting the redemption of the Company's stock.

         4.       WHOLE SHARES. You may exercise your option only for whole
shares of Common Stock.

         5.       SECURITIES LAW COMPLIANCE. Notwithstanding anything to the
contrary contained herein, you may not exercise your option unless the shares of
Common Stock issuable upon such exercise are then registered under the
Securities Act or, if such shares of Common Stock are not then so registered,
the Company has determined that such exercise and issuance would be exempt from
the registration requirements of the Securities Act. The exercise of your option
must also comply with other applicable laws and regulations governing your
option, and you may not exercise your option if the Company determines that such
exercise would not be in material compliance with such laws and regulations.

         6.       TERM. You may not exercise your option before the commencement
of its term or after its term expires. The term of your option commences on the
Date of Grant and expires upon the EARLIEST of the following:

         (a)      as of the date of the termination of your Continuous Service
                  if such termination is for Cause;

         (b)      three (3) months after the termination of your Continuous
                  Service for any reason other than Cause or your Disability or
                  death, provided that if during any part of such three (3)
                  month period your option is not exercisable solely because of
                  the condition set forth in the preceding paragraph relating to
                  "Securities Law Compliance," your option shall not expire
                  until the earlier of the Expiration Date or until it shall
                  have been exercisable for an aggregate period of three (3)
                  months after the termination of your Continuous Service;

         (c)      twelve (12) months after the termination of your Continuous
                  Service due to your Disability;

         (d)      twelve (12) months after your death if you die either during
                  your Continuous Service or within three (3) months after your
                  Continuous Service terminates;

         (e)      the Expiration Date indicated in your Grant Notice; or

         (f)      the day before the tenth (10th) anniversary of the Date of
                  Grant.


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If your option is an incentive stock option, note that, to obtain the federal
income tax advantages associated with an "incentive stock option," the Code
requires that at all times beginning on the date of grant of your option and
ending on the day three (3) months before the date of your option's exercise,
you must be an employee of the Company or an Affiliate, except in the event of
your death or Disability. The Company has provided for extended exercisability
of your option under certain circumstances for your benefit but cannot guarantee
that your option will necessarily be treated as an "incentive stock option" if
you continue to provide services to the Company or an Affiliate as a Consultant
or Director after your employment terminates or if you otherwise exercise your
option more than three (3) months after the date your employment terminates.

         7.       EXERCISE.

         (a)      You may exercise the vested portion of your option (and the
                  unvested portion of your option if your Grant Notice so
                  permits) during its term by delivering a Notice of Exercise
                  (in a form designated by the Company) together with the
                  exercise price to the Secretary of the Company, or to such
                  other person as the Company may designate, during regular
                  business hours, together with such additional documents as the
                  Company may then require.

         (b)      By exercising your option you agree that, as a condition to
                  any exercise of your option, the Company may require you to
                  enter into an arrangement providing for the payment by you to
                  the Company of any tax withholding obligation of the Company
                  arising by reason of (1) the exercise of your option, (2) the
                  lapse of any substantial risk of forfeiture to which the
                  shares of Common Stock are subject at the time of exercise, or
                  (3) the disposition of shares of Common Stock acquired upon
                  such exercise.

         (c)      If your option is an incentive stock option, by exercising
                  your option you agree that you will notify the Company in
                  writing within fifteen (15) days after the date of any
                  disposition of any of the shares of the Common Stock issued
                  upon exercise of your option that occurs within two (2) years
                  after the date of your option grant or within one (1) year
                  after such shares of Common Stock are transferred upon
                  exercise of your option.

         (d)      By exercising your option you agree that the Company (or a
                  representative of the underwriter(s)) may, in connection with
                  the first underwritten registration of the offering of any
                  securities of the Company under the Securities Act, require
                  that you not sell, dispose of, transfer, make any short sale
                  of, grant any option for the purchase of, or enter into any
                  hedging or similar transaction with the same economic effect
                  as a sale, any shares of Common Stock or other securities of
                  the Company held by you, for a period of time specified by the
                  underwriter(s) (not to exceed one hundred eighty (180) days)
                  following the effective date of the registration statement of
                  the Company filed under the Securities Act. You further agree
                  to execute and deliver such other agreements as may be
                  reasonably requested by the Company and/or the underwriter(s)
                  that are consistent with the foregoing or that are necessary
                  to give further effect thereto. In order to enforce the
                  foregoing covenant, the Company may


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                  impose stop-transfer instructions with respect to your shares
                  of Common Stock until the end of such period. The underwriters
                  of the Company's stock are intended third party beneficiaries
                  of this Section 7(d) and shall have the right, power and
                  authority to enforce the provisions hereof as though they were
                  a party hereto.

         8.       ACCELERATION ON CHANGE OF CONTROL. Notwithstanding any other
provisions of the Plan to the contrary, if (i) a Change in Control occurs and
(ii) within the period beginning as of the effective date of such Change in
Control and ending twenty-four (24) months after the effective date of such
Change in Control your Continuous Service terminates due to an involuntary
termination (not including death or Disability) without Cause or due to a
voluntary termination with Good Reason, then, as of the date of termination of
your Continuous Service, the vesting and exercisability of your option shall be
accelerated in full (and any reacquisition or repurchase rights held by the
Company with respect to such option shall lapse in full, as appropriate). For
purposes of the above provision regarding "Acceleration Upon a Change in Control
only, Good Reason means the occurrence of any of the following events,
conditions or actions taken by the Company without Cause and without your
consent: (i) a change in your employment responsibilities with the Company which
represents a material reduction in your level of responsibility, (ii) a
reduction in your level of base salary, or (iii) a relocation of your place of
employment by more than fifty (50) miles. Notwithstanding the foregoing, if you
have an individual written agreement with the Company or any Affiliate which
contains a different definition of Good Reason (or any analogous term), such
definition shall supersede the foregoing definition (it being understood,
however, that if no definition of Good Reason or any analogous term is set forth
in such an individual written agreement, the foregoing definition shall apply).

         9.       PARACHUTE PAYMENTS. If any payment or benefit you would
receive pursuant to a Change in Control from the Company or otherwise
("Payment") would (i) constitute a "parachute payment" within the meaning of
Section 280G of the Code, and (ii) but for this sentence, be subject to the
excise tax imposed by Section 4999 of the U.S. Internal Revenue Code (the
"Excise Tax"), then such Payment shall be reduced to the Reduced Amount. The
"Reduced Amount" shall be either (x) the largest portion of the Payment that
would result in no portion of the Payment being subject to the Excise Tax or (y)
the largest portion, up to and including the total, of the Payment, whichever
amount, after taking into account all applicable federal, state and local
employment taxes, income taxes, and the Excise Tax (all computed at the highest
applicable marginal rate), results in your receipt, on an after-tax basis, of
the greater amount of the Payment notwithstanding that all or some portion of
the Payment may be subject to the Excise Tax. If a reduction in payments or
benefits constituting "parachute payments" is necessary so that the Payment
equals the Reduced Amount, reduction shall occur in the following order unless
you elect in writing a different order (provided, however, that such election
shall be subject to Company approval if made on or after the effective date of
the event that triggers the Payment): reduction of cash payments; cancellation
of accelerated vesting of stock options and other equity-based awards; reduction
of employee benefits. In the event that acceleration of vesting of equity-based
compensation is to be reduced, such acceleration of vesting shall be cancelled
in the reverse order of the date of grant of such equity-based award unless you
elect in writing a different order for cancellation. The accounting firm engaged
by the Company for general audit purposes as of the day Prior to the effective
date of the Change in Control shall perform the foregoing calculations. If the
accounting firm so engaged by the Company is serving as accountant or auditor
for the individual, entity or group effecting the


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Change in Control, the Company shall appoint a nationally recognized accounting
firm to make the determinations required hereunder. The Company shall bear all
expenses with respect to the determinations by such accounting firm required to
be made hereunder. The accounting firm engaged to make the determinations
hereunder shall provide its calculations, together with detailed supporting
documentation, to you and the Company within fifteen (15) calendar days after
the date on which your right to a Payment is triggered (if requested at that
time by you or the Company) or such other time as requested by you or the
Company. If the accounting firm determines that no Excise Tax is payable with
respect to a Payment, either before or after the application of the Reduced
Amount, it shall furnish the Company and you with an opinion reasonably
acceptable to you that no Excise Tax will be imposed with respect to such
Payment. Any good faith determinations of the accounting firm made hereunder
shall be final, binding and conclusive upon you and the Company.

         10.      TRANSFERABILITY. Your option is not transferable, except by
will or by the laws of descent and distribution, and is exercisable during your
life only by you. Notwithstanding the foregoing, by delivering written notice to
the Company, in a form satisfactory to the Company, you may designate a third
party who, in the event of your death, shall thereafter be entitled to exercise
your option.

         11.      RIGHT OF FIRST REFUSAL. Shares of Common Stock that you
acquire upon exercise of your option are subject to any right of first refusal
that may be described in the Company's bylaws in effect at such time the Company
elects to exercise its right. The Company's right of first refusal shall expire
on the Listing Date.

         12.      RIGHT OF REPURCHASE. To the extent provided in the Company's
bylaws as amended from time to time, the Company shall have the right to
repurchase all or any part of the shares of Common Stock you acquire pursuant to
the exercise of your option.

         13.      OPTION NOT A SERVICE CONTRACT. Your option is not an
employment or service contract, and nothing in your option shall be deemed to
create in any way whatsoever any obligation on your part to continue in the
employ of the Company or an Affiliate, or of the Company or an Affiliate to
continue your employment. In addition, nothing in your option shall obligate the
Company or an Affiliate, their respective shareholders, Boards of Directors,
Officers or Employees to continue any relationship that you might have as a
Director or Consultant for the Company or an Affiliate.

         14.      WITHHOLDING OBLIGATIONS.

         (a)      At the time you exercise your option, in whole or in part, or
                  at any time thereafter as requested by the Company, you hereby
                  authorize withholding from payroll and any other amounts
                  payable to you, and otherwise agree to make adequate provision
                  for (including by means of a "cashless exercise" pursuant to a
                  program developed under Regulation T as promulgated by the
                  Federal Reserve Board to the extent permitted by the Company),
                  any sums required to satisfy the federal, state, local and
                  foreign tax withholding obligations of the Company or an
                  Affiliate, if any, which arise in connection with your option.


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         (b)      Upon your request and subject to approval by the Company, in
                  its sole discretion, and compliance with any applicable
                  conditions or restrictions of law, the Company may withhold
                  from fully vested shares of Common Stock otherwise issuable to
                  you upon the exercise of your option a number of whole shares
                  of Common Stock having a Fair Market Value, determined by the
                  Company as of the date of exercise, not in excess of the
                  minimum amount of tax required to be withheld by law. If the
                  date of determination of any tax withholding obligation is
                  deferred to a date later than the date of exercise of your
                  option, share withholding pursuant to the preceding sentence
                  shall not be permitted unless you make a proper and timely
                  election under Section 83(b) of the Code, covering the
                  aggregate number of shares of Common Stock acquired upon such
                  exercise with respect to which such determination is otherwise
                  deferred, to accelerate the determination of such tax
                  withholding obligation to the date of exercise of your option.
                  Notwithstanding the filing of such election, shares of Common
                  Stock shall be withheld solely from fully vested shares of
                  Common Stock determined as of the date of exercise of your
                  option that are otherwise issuable to you upon such exercise.
                  Any adverse consequences to you arising in connection with
                  such share withholding procedure shall be your sole
                  responsibility.

         (c)      You may not exercise your option unless the tax withholding
                  obligations of the Company and/or any Affiliate are satisfied.
                  Accordingly, you may not be able to exercise your option when
                  desired even though your option is vested, and the Company
                  shall have no obligation to issue a certificate for such
                  shares of Common Stock or release such shares of Common Stock
                  from any escrow provided for herein.

         15.      NOTICES. Any notices provided for in your option or the Plan
shall be given in writing and shall be deemed effectively given upon receipt or,
in the case of notices delivered by mail by the Company to you, five (5) days
after deposit in the United States or Canadian mail, or one (1) day after
deposit with an internationally recognized overnight courier, specifying next
day delivery, postage prepaid, addressed to you at the last address you provided
to the Company.

         16.      GOVERNING PLAN DOCUMENT. Your option is subject to all the
provisions of the Plan, the provisions of which are hereby made a part of your
option, and is further subject to all interpretations, amendments, rules and
regulations which may from time to time be promulgated and adopted pursuant to
the Plan. In the event of any conflict between the provisions of your option and
those of the Plan, the provisions of the Plan shall control.