1 Subject: Question re: 2010 Inhalational toxicology paper

Attachments: twopoll.xls; Copy of Inhal Tox_Figures_Estimates.xls

From: "Brüske, Irene, Dr." [mailto:brueske@helmholtz

‐ muenchen.de]

Sent: Monday, June 30, 2014 7:46 AM

To: Patel, Molini

Cc: Hampel, Regina, Dr.; Wolf, Kathrin, Dr.

Subject: WG: question re: 2010 Inhalational toxicology paper

Dear Molini,

please find the data for the two pollutant models in the attachment. Mono

= monocytes, PLT

= platelets, and se ggran mean s "segmentkernige Granulozyten"

= PMC.

I hope this was what you needed

Best regards,

Irene

Von: Patel, Molini [mailto:Patel.Molini@epa.gov]

Gesendet: Dienstag, 17. Juni 2014 22:03

An: Brüske, Irene, Dr.

Betreff: RE: question re: 2010 Inhalational toxicology paper

Hello Irene,

Thank you so much for sending these results so qui ckly. I a pologize for my delay in

responding, but I only now had a chance to look at the excel file carefully. In the last

paragraph of the results section of your paper, you mention results with adjustment for a

second pollutant. If you examined two

‐ pollutant models with NO or NO2

, we wo uld appreciate

you sharing the quantitative results for NO/NO2 and copollutants from those models.

Thank you again, Molini

Molini M. Patel, PhD, MPH

Epidemiologist

U.S. Environmental Protection Agency

National Center for Environmental Assessment

Mailcode: B243

‐ 01

Research Triangle Park, NC 27711

Phone: 919.541.1492, Fax: 919.541.1818, Email:

patel.molini@epa.gov<mailto:patel.molini@epa.gov>

From: " Brüske, Ir ene, Dr." [mailto:brueske@helmholtz

‐ muenchen.de]

Sent: Tuesday, June 03, 2014 4:59 AM

To: Patel, Molini

Subject: AW: question re: 2010 Inhalational toxicology paper

Dear Molini,

I hope these are the data (attachment) you were looking for. Please, let me know, if you need

something different.

Best regards,

Irene2 Von: Patel, Molini [mailto:Patel.Molini@epa.gov]

Gesendet: Donnerstag, 22. Mai 2014 20:08

An: Brüske, Irene, Dr.

Betreff: question re: 2010 Inhalational toxicology paper

Dear Irene,

Our office is currently developing the Integrated Science Assessment of Oxides of Nitrogen

and reviewing your 2010 paper in Inhalation Toxicology, "Impact of ambient air pollution on

the dif ferential white blood cell count in patients with chronic obstructive pulmonary

disease."

We are interested in the results you report in Figure 2 for associations of gaseous

pollutants and white blood cell counts and hope you would share with us the quantitative

results (effect estimates and 95% CI) for NO2, NO, and CO

. Would you also share with us

quantitative results for copollutants models conducted with NO and NO2? In the paper, these

results are reported only in text form.

Thank you for your consideration!

Molini

Molini M. Patel, PhD, MPH

Epidemiologist

U.S. Environmental Protection Agency

National Center for Environmental Assessment

Mailcod e: B243

‐ 01

Research Triangle Park, NC 27711

Phone: 919.541.1492, Fax: 919.541.1818, Email:

patel.molini@epa.gov<mailto:patel.molini@epa.gov>

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Helmholtz Zentrum München

Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Ingolstädter Landstr. 1

85764 Neuherberg

www.helmholtz

‐ muenchen.de

Aufsichtsratsvorsitzende: MinDir ́in Bärbel Brumme

‐ Bothe

Geschäftsführer: Prof. Dr. Günther Wess, Dr. Nikolaus Blum, Dr. Alfons Enhsen

Registergericht: Amtsgericht München HRB 6466

USt

‐ IdNr: DE 129521671