I 

114TH CONGRESS 

1ST SESSION H. R. 3537 

To amend the Controlled Substances Act to clarify how controlled substance 

analogues are to be regulated, and for other purposes. 

IN THE HOUSE OF REPRESENTATIVES 

SEPTEMBER 17, 2015 

Mr. DENT (for himself, Mr. HIMES, Mr. MEEHAN, Mr. DOLD, Mr. TIBERI, 

Mr. COSTELLO of Pennsylvania, Mr. HANNA, Mr. THOMPSON of Pennsylvania, Mr. ROGERS of Kentucky, Mr. MURPHY of Pennsylvania, Mr. 

BARLETTA, Ms. NORTON, Mr. LANCE, Mrs. COMSTOCK, Mr. KATKO, Ms. 

ROS-LEHTINEN, and Mr. JOLLY) introduced the following bill; which was 

referred to the Committee on Energy and Commerce, and in addition to 

the Committee on the Judiciary, for a period to be subsequently determined by the Speaker, in each case for consideration of such provisions 

as fall within the jurisdiction of the committee concerned 

A BILL 

To amend the Controlled Substances Act to clarify how controlled substance analogues are to be regulated, and for 

other purposes. 

1 Be it enacted by the Senate and House of Representa2 tives of the United States of America in Congress assembled, 

3 SECTION 1. SHORT TITLE. 

4 This Act may be cited as the ‘‘Synthetic Drug Con5 trol Act of 2015’’. 


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1 SEC. 2. CONTROLLED SUBSTANCE ANALOGUES. 

2 (a) EXPANSION OF DEFINITION.— 

3 (1) IN GENERAL.—Clauses (i), (ii), and (iii) of 

4 section 102(32)(A) of the Controlled Substances Act 

5 (21 U.S.C. 802(32)(A)) are amended by striking 

6 ‘‘substantially’’ each place it appears. 

7 (2) RULE OF CONSTRUCTION.—Section 

8 102(32)(A) of the Controlled Substances Act (21 

9 U.S.C. 82(32)(A)) shall not be construed to require 

10 that a substance satisfy more than one of the 

11 clauses listed in such section 102(32)(A) to meet the 

12 definition of a controlled substance analogue. 

13 (b) LIMITATION ON TREATMENT AS CONTROLLED

14 SUBSTANCES.—Section 203 of the Controlled Substances 

15 Act (21 U.S.C. 813) is amended by inserting before the 

16 period at the end the following: ‘‘for purposes of prohibi17 tions, restrictions, and other requirements with respect to 

18 manufacture, importation, distribution, and sale’’. 

19 SEC. 3. TREATMENT OF CERTAIN DESIGNER DRUGS AS 

20 SCHEDULE I CONTROLLED SUBSTANCES. 

21 (a) IN GENERAL.—Schedule I, as set forth in section 

22 202(c) of the Controlled Substances Act (21 U.S.C. 

23 812(c)) is amended by adding at the end the following: 

24 ‘‘(e)(1) Unless specifically exempted or unless listed 

25 in another schedule, any material, compound, mixture, or 

26 preparation which contains any quantity of a substances 


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1 listed in paragraphs (2) through (10), or which contains 

2 the salts, isomers, and salts of isomers thereof whenever 

3 the existence of such salts, isomers, and salts of isomers 

4 is possible within the specific chemical designation. 

5 ‘‘(2) PHENYLALKYLAMINES.—The substances listed 

6 in this paragraph consist of the following 

7 phenylalkylamines: 

8 ‘‘(A) 2–(ethylamino)–1–(4-methylphenyl)–1- 

9 propanone. 

10 ‘‘(B) 1–(4-ethylphenyl)–2–(methylamino)–1- 

11 propanone. 

12 ‘‘(C) 1–(3-fluorophenyl)–2–(methylamino)–1- 

13 propanone. 

14 ‘‘(D) 1–(4-fluorophenyl)–2–(methylamino)–1- 

15 propanone. 

16 ‘‘(E) 1–(4-methoxyphenyl)–2–(methylamino)–1- 

17 propanone. 

18 ‘‘(F) 2–(ethylamino)–1–(4-methoxyphenyl)–1- 

19 propanone. 

20 ‘‘(G) 1–(2-naphthalenyl)–2–(1-pyrrolidinyl)–1- 

21 pentanone. 

22 ‘‘(H) 1–(1,3-benzodioxol-5-yl)–2–(ethylamino)– 

23 1-propanone. 

24 ‘‘(I) 1–(1,3-benzodioxol-5-yl)–2–(methylamino)– 

25 1-butanone. 


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1 ‘‘(J) 1–(1,3-benzodioxol-5-yl)–2– 

2 (methylamino)–1-pentanone. 

3 ‘‘(K) 2–(ethylamino)–1-phenyl-1-propanone. 

4 ‘‘(L) 1-phenyl-2–(1-pyrrolidinyl)–1-propanone. 

5 ‘‘(M) 1–(4-methylphenyl)–2–(1-pyrrolidinyl)–1- 

6 propanone. 

7 ‘‘(N) 1–(4-methoxyphenyl)–2–(1-pyrrolidinyl)– 

8 1-propanone. 

9 ‘‘(O) 1–(1,3-benzodioxol-5-yl)–2–(1- 

10 pyrrolidinyl)–1-propanone. 

11 ‘‘(P) 1-phenyl-2–(1-pyrrolidinyl)–1-pentanone. 

12 ‘‘(Q) 2-amino-1–(4-fluoro)–1-propanone. 

13 ‘‘(R) 2–(methylamino)–1-phenyl-1-pentanone. 

14 ‘‘(S) 2–(ethylamino)–1–(4-ethylphenyl)–1- 

15 propanone. 

16 ‘‘(T) 2–(dimethylamino)–1-phenyl-1-propanone. 

17 ‘‘(U) 1–(1,3-benzodioxol-5-yl)–2–(1- 

18 pyrrolidinyl)–1-butanone. 

19 ‘‘(V) 1–(methylphenyl)–2–(1-pyrrolidinyl)–1- 

20 hexanone. 

21 ‘‘(W) 2–(methylamino)–1-phenyl-1-butanone. 

22 ‘‘(X) 2–(methylamino)–1-p-tolyl-1-butanone. 

23 ‘‘(Y) 1–(4-methylphenyl)–2–(1-pyrrolidinyl)–1- 

24 butanone. 


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1 ‘‘(Z) 1–(3,4-dimethylphenyl)–2–(methylamino)– 

2 1-propanone. 

3 ‘‘(AA) 1-phenyl-2–(1-pyrrolidinyl)–1-butanone. 

4 ‘‘(BB) 1–(1,3-benzodioxol-5-yl)–2– 

5 (dimethylamino)–1-propanone. 

6 ‘‘(CC) 1–(4-methylphenyl)–2–(benzylamino)–1- 

7 propanone. 

8 ‘‘(DD) 1–(1-naphthy)–2–(1-pyrrolidinyl)–1- 

9 pentanone. 

10 ‘‘(EE) 1–(1,3-benzodioxol-5-yl)–2– 

11 (benzylamino)–1-propanone. 

12 ‘‘(FF) 1–(1,3-benzodioxol-5-yl)–2– 

13 (benzylamino)–1-butanone. 

14 ‘‘(GG) 1–(1,3-benzodioxol)–2-[hydroxy(methyl)- 

15 amino]-1-propanone. 

16 ‘‘(HH) 1–(1,3-benzodioxol-5-yl)–2– 

17 (dimethylamino)–1-butanone. 

18 ‘‘(II) 2–(ethyl(methyl)amino)–1-phenyl-buta19 none. 

20 ‘‘(JJ) 1–(4-bromophenyl)–2–(methylamino)–1- 

21 propanone. 

22 ‘‘(KK) 2–(ethyl(methyl)amino-1-phenyl-1- 

23 propanone. 

24 ‘‘(LL) 2–(methylamino)–1-m-tolyl-1-propanone. 


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1 ‘‘(MM) 2–(pyrrolidin-1-yl)–1–(thiophen-2-yl)–1- 

2 pentanone. 

3 ‘‘(NN) 1–(4-fluorophenyl)–2–(methylamino)–1- 

4 butanone. 

5 ‘‘(OO) 1–(4-methoxyphenyl)–2–(pyrrolidin-1- 

6 yl)–1-butanone. 

7 ‘‘(PP) 1–(4-ethylphenyl)–2–(pyrrolidin-1-yl)–1- 

8 butanone. 

9 ‘‘(QQ) 1–(4-methoxy-3-methylphenyl)–2– 

10 (methylamino)–1-propanone. 

11 ‘‘(RR) 2–(ethylamino)–1–(3-methylphenyl)–1- 

12 propanone. 

13 ‘‘(SS) 2-amino-(1H-indol-5-yl)propan-1-one. 

14 ‘‘(TT) 1-phenyl-2–(piperidin-1-yl)butan-1-one. 

15 ‘‘(UU) 2-methylamino-1–(2,4,5- 

16 trimethylphenyl)-propan-1-one). 

17 ‘‘(VV) 1-phenyl-2–(pyrrolidin-1-yl)heptan-1-one. 

18 ‘‘(WW) 1-phenyl-2–(pyrrolidin-1-yl)hexan-1-one. 

19 ‘‘(XX) 1–(4-fluorophenyl)–2–(pyrrolidin-1- 

20 yl)pentan-1-one. 

21 ‘‘(YY) 1–(benzo[d][1,3]dioxol-5-yl)–2– 

22 (dimethylamino)pentan-1-one. 

23 ‘‘(ZZ) 1–(2-fluorophenyl)–N-methyl-propan-2- 

24 amine. 

25 ‘‘(AAA) 1–(2-fluorophenyl)-propan-2-amine. 


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1 ‘‘(BBB) 1–(3-fluorophenyl)- propan-2-amine. 

2 ‘‘(CCC) 1–(3-fluorophenyl)–N-methyl-propan-2- 

3 amine. 

4 ‘‘(DDD) 1–(4-fluorophenyl)- propan-2-amine. 

5 ‘‘(EEE) 1–(4-fluorophenyl)–N-methyl-propan-2- 

6 amine. 

7 ‘‘(FFF) 1–(4-methylphenyl)propan-2-amine. 

8 ‘‘(GGG) N-ethyl-N-methyl-1-phenylpropan-2- 

9 amine. 

10 ‘‘(HHH) 1–(benzofuran-4-yl)propan-2-amine. 

11 ‘‘(III) 1–(benzofuran-5-yl) propan-2-amine. 

12 ‘‘(JJJ) 1–(2,3-dihydrobenzofuran-5-yl)proan-2- 

13 amine. 

14 ‘‘(KKK) 1–(benzofuran-6-yl)- propan-2-amine. 

15 ‘‘(LLL) 1–(2,3-dihydrobenzofuran-6-yl)proan-2- 

16 amine. 

17 ‘‘(MMM) 1–(4-methoxyphenyl)–N-methyl18 propan-2-amine. 

19 ‘‘(NNN) N,N-dimethyl-1-phenylpropan-2-amine. 

20 ‘‘(OOO) 1–(2,3-dihydro-1H-inden-5-yl)propan21 2-amine. 

22 ‘‘(PPP) 5,6,7,8-tetrahydrobenzo[1,3]- 

23 benzodioxol-7-amine. 

24 ‘‘(QQQ) a-methyl-4–(methylthio)-benzene25 ethanamine. 


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1 ‘‘(RRR) 1–(4-chlorophenyl)-propan-2-amine. 

2 ‘‘(SSS) 1–(2,4,6-trimethoxyphenyl)-propan-2- 

3 amine. 

4 ‘‘(TTT) 1–(2,4,5-trimethoxyphenyl)-propan-2- 

5 amine. 

6 ‘‘(UUU) 1–(2,5-dimethylphenyl)-propan-2- 

7 amine. 

8 ‘‘(VVV) 1–(3,4-dimethylphenyl)-propan-2- 

9 amine. 

10 ‘‘(WWW) N–(1-phenylpropan-2-yl)propan-1- 

11 amine. 

12 ‘‘(XXX) 4–(2-aminopropyl)phenol. 

13 ‘‘(YYY) 3,4-methylenedioxy-N,N-dimethyl-am14 phetamine. 

15 ‘‘(ZZZ) N-ethyl-1–(4-methoxyphenyl)propan-2- 

16 amine. 

17 ‘‘(AAAA) 1–(benzofuran-5-yl)–N-methylpropan18 2-amine. 

19 ‘‘(BBBB) 6,7-dihydro-5H-inden[5,6- 

20 d][1,3]dioxol-6-amine. 

21 ‘‘(CCCC) 5-iodo-2,3-dihydro-1H-inden-2-amine. 

22 ‘‘(DDDD) 2,3-dihydro-1H-inden-2-amine. 

23 ‘‘(EEEE) 5-methoxy-6-methyl-2,3-dihydro-1H24 inden-2-amine. 


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•HR 3537 IH

1 ‘‘(FFFF) N-methyl-6,7-dihydro-5H2 cyclopenta[1,3]-benzodioxol-6-amine. 

3 ‘‘(GGGG) N-methyl-2,3-dihydro-1H-inden-2- 

4 amine. 

5 ‘‘(HHHH) 2-[4–(2-fluoroethylthio)–2,5- 

6 dimethoxyphenyl]ethanamine. 

7 ‘‘(IIII) 8-bromo-2,3,6,7-tetrahydro-benzo[1,2- 

8 b;4,5-b’]difuran-4-ethanamine. 

9 ‘‘(JJJJ) 4-iodo-2,5-dimethoxy-N-[(2- 

10 methoxyphenyl)-methyl-benzene-ethamine. 

11 ‘‘(KKKK) 2–(4-chloro-2,5-dimethoxyphenyl)– 

12 N–(2-methoxybenzyl)-ethanamine. 

13 ‘‘(LLLL) 2–(2,5-dimethoxy-3,4- 

14 dimethylphenyl)-ethanamine. 

15 ‘‘(MMMM) 2–(4-methyl-2,5-dimethoxyphenyl)– 

16 N–(2-methoxybenzyl)-ethanamine. 

17 ‘‘(NNNN) 2–(4-ethyl-2,5-dimethoxyphenyl)–N– 

18 (2-methoxybenzyl)-ethanamine. 

19 ‘‘(OOOO) 2–(2,5-dimethoxy-3,4- 

20 dimethylphenyl)–N–(2-methoxybenzyl)-ethanamine. 

21 ‘‘(PPPP) 2–(2,5-dimethoxyphenyl)–N–(2-me22 thoxybenzyl)-ethanamine. 

23 ‘‘(QQQQ) 2–(4-bromo-2,5-dimethoxyphenyl)– 

24 N–(2-methoxybenzyl)-ethanamine. 


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•HR 3537 IH

1 ‘‘(RRRR) 2–(2,5-dimethoxyphenyl-4-nitro)–N2 [(2-methoxyphenyl)methyl]-ethanamine. 

3 ‘‘(SSSS) 1–(4-iodo-2,5- 

4 dimethoxyphenyl)propan-2-amine. 

5 ‘‘(TTTT) 1–(4-bromofuro[2,3-f]benzofuran-8- 

6 yl)propan-2-amine. 

7 ‘‘(UUUU) 1–(4-chloro-2,5- 

8 dimethoxyphenyl)propan-2-amine. 

9 ‘‘(VVVV) 1–(4-bromo-2,3,6,7- 

10 terahydrofuro[2,3-f]benzofuran-8-yl)propan-2-amine. 

11 ‘‘(WWWW) (2,5-dimethoxyphenyl)-propan-2- 

12 amine. 

13 ‘‘(XXXX) 1-[4–(ethylthio)–2,5- 

14 dimethoxyphenyl)propan-2-amine. 

15 ‘‘(YYYY) 1–(4-ethoxy-2,5- 

16 dimethoxyphenyl)propan-2-amine. 

17 ‘‘(ZZZZ) 1-[2,5-dimethoxy-4– 

18 (propylthio)phenyl]propan-2-amine. 

19 ‘‘(AAAAA) 1–(4-ethyl-2,5- 

20 dimethoxyphenyl)propan-2-amine. 

21 ‘‘(BBBBB) N-benzyl-2-phenylethanamine. 

22 ‘‘(CCCCC) N,N-dimethyl-2-phenylethanamine. 

23 ‘‘(DDDDD) 6-chloro-aminotetralin. 

24 ‘‘(EEEEE) 2-phenyl-propan-1-amine. 

25 ‘‘(FFFFF) 2-phenethylamine. 


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•HR 3537 IH

1 ‘‘(GGGGG) 1-methylamino-1–(3,4- 

2 methylendioxy-phenyl)propane. 

3 ‘‘(HHHHH) N-methyl-3- 

4 phenylbicyclo[2.2.1]heptan-2-amine. 

5 ‘‘(IIIII) 1–(2-methoxyphenyl)–N-methylpropan6 2-amine. 

7 ‘‘(JJJJJ) 2–(4–(allyloxy)–3,5- 

8 dimethoxyphenyl)ethanamine. 

9 ‘‘(KKKKK) 4-methylhexan-2-amine. 

10 ‘‘(LLLLL) 4-methyl-5-phenyl-2-amino11 oxazoline. 

12 ‘‘(MMMMM) N-methyl-1-thiophen-2-yl)propan13 2-amine. 

14 ‘‘(NNNNN) (3-dimethylamino-2,2- 

15 dimethylpropyl)–4-aminobenzoate. 

16 ‘‘(OOOOO) 1–(4-fluorophenyl)–2– 

17 (methylamino)-propan-1-ol. 

18 ‘‘(PPPPP) 4-methyl-5-p-tolyl-4,5-dihydrooxazol19 2-amine. 

20 ‘‘(QQQQQ) 1-phenyl-2–(pyrrolidin-1-yl)propan21 1-ol. 

22 ‘‘(3) CANNABIMIMETIC AGENTS.—The substances 

23 listed in this paragraph consist of the following 

24 cannabimimetic agents: 


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1 ‘‘(A) (4-ethyl-1-naphthalenyl)(1-pentyl-1H2 indol-3-yl)methanone. 

3 ‘‘(B) 2–(2-methylphenyl)–1–(1-pentyl-1H-indol4 3-yl)-ethanone. 

5 ‘‘(C) 1-[1–(2-cyclohexylethyl)–1H-indol-3-yl]-2– 

6 (2-methoxyphenyl)-ethanone. 

7 ‘‘(D) [1–(5-fluoropentyl)–1H-indol-3-yl](2- 

8 iodophenyl)methanone. 

9 ‘‘(E) (2-methyl-1-[(1-methylpiperidin-2- 

10 yl)methyl]-6-nitro-1H-indol-3-yl)methanone. 

11 ‘‘(F) (1-butyl-1H-indol-3-yl)(4-methoxyphenyl)- 

12 methanone. 

13 ‘‘(G) (1-butyl-1H-indol-3-yl)(4- 

14 methylnaphthalen-1-yl)methanone. 

15 ‘‘(H) [1–(5-fluoropentyl)–1H-indol-3-yl](4- 

16 methyl-1-naphthalenyl)-methanone. 

17 ‘‘(I) [1-[(1-methyl-2-piperidinyl)methyl]-1H18 indol-3-yl]-1-naphthalenyl-methanone. 

19 ‘‘(J) 3–(4-methoxyphenyl)–2-methyl-1-[(2–(4- 

20 morpholinyl)ethyl)–1H-indol-3-yl]-methanone. 

21 ‘‘(K) [2,3-dihydro-5-methyl-3–(4- 

22 morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin23 6-yl]-1-naphthalenyl- methanone. 

24 ‘‘(L) 2–(3-methoxyphenyl)–1–(1-pentyl-1H25 indol-3-yl)-ethanone. 


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•HR 3537 IH

1 ‘‘(M) (2-iodophenyl)[1-[(1-methyl-2- 

2 piperidinyl)methyl]-1H-indol-3-yl]-methanone. 

3 ‘‘(N) [1-[(1-methyl-2-piperdinyl)methyl]-1H4 indol-3-yl]tricycle[3.3.1.13,7]dec-1-yl-methanone. 

5 ‘‘(O) 1-naphthalenyl(1-propyl-1H-indol-3-yl)- 

6 methanone. 

7 ‘‘(P) 5-[3–(1-naphthoyl)–1H-indole-1- 

8 yl]pentanenitrile. 

9 ‘‘(Q) 3–(1-naphthenylmethyl)–1-pentyl-1H10 indole. 

11 ‘‘(R) (2-methyl-1-propyl-1H-indol-3-yl)–1- 

12 napthalenyl-methanone. 

13 ‘‘(S) 1-naphthalenyl[1–(4-penten-1-yl)–1H14 indol-3-yl]-methanone. 

15 ‘‘(T) (4-bromonaphthalen-1-yl)(1-pentyl-1H16 indol-3-yl)methanone. 

17 ‘‘(U) (4-fluoronaphthalen-1-yl)(1-pentyl-1H18 indol-3-yl)methanone. 

19 ‘‘(V) (2-methyl-1-phenyl-1H-indol-3-yl)–1- 

20 naphthalenyl-methanone. 

21 ‘‘(W) 2–(2-chlorophenyl)–1–(1-pentyl-1H-indol22 3-yl)-ethanone. 

23 ‘‘(X) [1–(5-chloropentyl)–1H-indol-3-yl](2- 

24 iodophenyl)-methanone. 


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•HR 3537 IH

1 ‘‘(Y) (adamantan-1-yl)(1-pentyl-1H-indol-3-yl)- 

2 methanone. 

3 ‘‘(Z) (2-iodo-5-nitrophenyl)-[1–(1- 

4 methylpiperidin-2-ylmethyl)–1H-indol-3-yl]- 

5 methanone. 

6 ‘‘(AA) (1-pentyl-1H-indol-3-yl)(2,2,3,3- 

7 tetramethylcyclo-propyl)methanone. 

8 ‘‘(BB) [1–(5-fluoropentyl-1H-indol-3- 

9 yl)](2,2,3,3-tetramethylcyclo-propyl)methanone. 

10 ‘‘(CC) [1–(2-morpholinoethyl)–1H-indol-3- 

11 yl](2,2,3,3-tetramethylcyclopropyl)methanone. 

12 ‘‘(DD) 1-[(tetrahydro-2H-pyran-4-yl)methyl]- 

13 1H-indol-3-yl-(2,2,3,3- 

14 tetramethylcyclopropyl)methanone. 

15 ‘‘(EE) 1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl16 1H-indole-3-carboxamide. 

17 ‘‘(FF) 1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl18 1H-indazole-3-carboxamide. 

19 ‘‘(GG) 1–(5-fluoropentyl)–N20 tricyclo[3.3.1.13,7]dec-1-yl-1H-indole-3-carboxamide. 

21 ‘‘(HH) [1–(5-chloropentyl)–1H-indol-3- 

22 yl](2,2,3,3-tetramethylcyclopropyl)methanone. 

23 ‘‘(II) (1-isopentyl-1H-indol-3-yl)(naphthalen-1- 

24 yl)methanone. 


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•HR 3537 IH

1 ‘‘(JJ) 1–(5-fluoropentyl-N2 tricyclo[3.3.1.13,7]dec-1-yl-1H-indazole-3- 

3 carboxamide. 

4 ‘‘(KK) (1-pentyl-1H-indol-3-yl)(4-propyl-1- 

5 naphthalenyl)-methanone. 

6 ‘‘(LL) [1–(5-chloropentyl)–1H-indol-3- 

7 yl](2,2,3,3-tetramethylcyclopropyl)methanone. 

8 ‘‘(MM) (4-methyl-naphthalen-1-yl)[1–(pent-4- 

9 en-1-yl)–1H-indol-3-yl]methanone. 

10 ‘‘(NN) (2-methoxy-1-naphthalenyl)(1-pentyl11 1H-indol-3-yl)methanone. 

12 ‘‘(OO) (3-methoxy-phenyl)(1-pentyl-1H-indol-3- 

13 yl)methanone. 

14 ‘‘(PP) [1–(5-fluoropentyl)–1H-indol-3-yl](4- 

15 ethyl-1-naphthalenyl)-methanone. 

16 ‘‘(QQ) quinolin-8-yl 1-pentyl-1H-indole-3- 

17 carboxylate. 

18 ‘‘(RR) quinolin-8-yl 1–(5-fluoropentyl-1H19 indole-3-carboxylate. 

20 ‘‘(SS) 1–(cyclohexylmethyl)–8-quinolinyl-ester21 1H-indole-3-carboxylic acid. 

22 ‘‘(TT) N–(1-amino-3-methyl-1-oxobutan-2-yl)– 

23 1-pentyl-1H-indazole-3-carboxamide. 

24 ‘‘(UU) 1–(5-fluoropentyl)–N–(naphthalene-1- 

25 yl)–1H-indole-3-carboxamide. 


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•HR 3537 IH

1 ‘‘(VV) N–(1-amino-3-methyl-1-oxobutan-2-yl)– 

2 1–(4-fluorobenzyl)–1H-indazole-3-carboxamide. 

3 ‘‘(WW) N–(1-amino-3,3-dimethyl-1-oxobutan-2- 

4 yl)–1–(4-fluorobenzyl)–1H-indazole-3-carboxamide. 

5 ‘‘(XX) N–(1-amino-3,3-dimethyl-1-oxobutan-2- 

6 yl)–1-pentyl-1H-indole-3-carboxamide. 

7 ‘‘(YY) 2-iodophenyl)(1-pentyl-1H-indol-3- 

8 yl)methanone. 

9 ‘‘(ZZ) [5–(2-methylphenyl)–1-pentyl-1H-pyrrol10 3-yl]-1-naphthalenyl-methanone. 

11 ‘‘(AAA) 1-pentyl-N–(naphthalene-1-yl)–1H12 indole-3-carboxamide. 

13 ‘‘(BBB) 1–(5-chloropentyl)–1H-indol-3-yl](4- 

14 methyl-1-naphthalenyl)-methanone. 

15 ‘‘(CCC) (4-methyl-naphthalen-1-yl)[2-methyl-1– 

16 (pent-4-en-1-yl)–1H-indol-3-yl)]methanone. 

17 ‘‘(DDD) [1–(5-fluoropentyl)–1H-indol-3-yl](o18 tolyl)methanone. 

19 ‘‘(EEE) (2-ethylphenyl)(1–(5-fluoropentyl)–1H20 indol-3-yl)methanone. 

21 ‘‘(FFF) [1–(5-chloropentyl)–1H-indol-3- 

22 yl](naphthalen-1-yl)methanone. 

23 ‘‘(GGG) [1–(5-bromopentyl)–1H-indol-3- 

24 yl](naphthalen-1-yl)methanone. 


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•HR 3537 IH

1 ‘‘(HHH) (1–(5-fluoropentyl)–1H-indazol-3- 

2 yl)(naphthalene-1-yl)methanone. 

3 ‘‘(III) 1-[(1-methyl-2-piperidinyl)methyl]-1H4 indol-3-yl](2,2,3,3- 

5 tetramethylcyclopropyl)methanone. 

6 ‘‘(JJJ) (1–(1-methylazepan-2-yl)–1H-indol-3- 

7 yl)(2,2,3,3-tetramethylcyclopropyl)methanone. 

8 ‘‘(KKK) 4-hydroxy-3,3,4-trimethyl-1–(1-pentyl9 1H-indol-3-yl)pentan-1-one. 

10 ‘‘(LLL) [1–(4-fluoropentyl)–1H-indol-3-yl]-1- 

11 naphthenyl-methanone. 

12 ‘‘(MMM) 2–(2-iodophenyl)–1–(1-pentyl-1H13 indol-3-yl)ethanone. 

14 ‘‘(NNN) (1-hexyl-1H-indol-3-yl)(2,2,3,3- 

15 tetramethylcyclopropyl)methanone. 

16 ‘‘(OOO) (2,2,3,3-tetramethylcyclopropyl)[1– 

17 (4,4,4-trifluorobutyl)–1H-indol-3-yl]methanone. 

18 ‘‘(PPP) 7-methoxy-1–(2-morpholinoethyl)–N– 

19 ((1S,4R)–1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl)– 

20 1H-indole-3-ca rboxamide. 

21 ‘‘(QQQ) quinolin-8-yl 1–(4-fluorobenzyl)–1H22 indole-3-carboxylate. 

23 ‘‘(RRR) naphthalen-1-yl 1–(4-fluorobenzyl)– 

24 1H-indole-3-carboxylate. 


SSpencer on DSK4SPTVN1PROD with BILLS
18 

•HR 3537 IH

1 ‘‘(SSS) N–(1-amino-3,3-dimethyl-1-oxobutan-2- 

2 yl)–1-pentyl-1H-indazole-3-carboxamide. 

3 ‘‘(TTT) N–(1-amino-3,3-dimethyl-1-oxobutan-2- 

4 yl)–1–(5-fluoropentyl)–1H-indole-3-carboxamide. 

5 ‘‘(UUU) (1–(4-fluoropentyl)–1H-indol-3- 

6 yl)(2,2,3,3-tetramethylcyclopropyl)methanone. 

7 ‘‘(VVV) 1-naphthalenyl(1-pentyl-1H-indazol-3- 

8 yl)methanone. 

9 ‘‘(WWW) N-naphthalenyl-1-pentyl-1H-indazole10 3-carboxamide. 

11 ‘‘(XXX) N–(1-amino-3-methyl-1-oxobutan-2- 

12 yl)–1–(cyclohexyl methyl)–1H-indazole-3- 

13 carboxamide. 

14 ‘‘(YYY) naphthalene-1-yl(9-pentyl-9H-carbazol15 3-yl)methanone. 

16 ‘‘(ZZZ) naphthalene-1-yl 1–(5-fluoropentyl)– 

17 1H-indole-3-carboxylate. 

18 ‘‘(AAAA) methyl 3-methyl-2–(1-pentyl-1H-inda19 zole-3-carboxamido. 

20 ‘‘(BBBB) methyl 2–(1–5-fluoropentyl)–1H-in21 dazole-3-caboxamido)–3-methylbutanoate. 

22 ‘‘(CCCC) N-benzyl-1-pentyl-1H-indole-3- 

23 carboxamide. 

24 ‘‘(DDDD) N-benzyl-1–(5-fluoropentyl)–1H25 indole-3-carboxamide. 


SSpencer on DSK4SPTVN1PROD with BILLS
19 

•HR 3537 IH

1 ‘‘(EEEE) methyl 2–(1–(4-fluorobenzyl)–1H-in2 dazole-3-carboxamido)–3-methylbutanoate. 

3 ‘‘(FFFF) quinolin-8-yl 1-pentyl-1H-indazole-3- 

4 carboxylate. 

5 ‘‘(GGGG) quinolin-8-yl 1–(5-fluoropentyl)–1H6 indazole-3-carboxylate. 

7 ‘‘(HHHH) naphthalene-2-yl 1–(2- 

8 fluorophenyl)–1H-indazole-3-carboxylate. 

9 ‘‘(IIII) N–(1-amino-3,3-dimethyl-1-oxobutan-2- 

10 yl)–1–(cyclohexylmethyl)–1H-indazole-3- 

11 carboxamide. 

12 ‘‘(JJJJ) (1–(4-flourobenzyl)–1H-indol-3- 

13 yl)(2,2,3,3-tetramethylcyclopropyl)methanone. 

14 ‘‘(KKKK) N–(1-amino-1-oxo—3-phenylpropan15 2-yl)–1–(5-fluoropentyl)–1H-indole-3-carboxamide. 

16 ‘‘(LLLL) N–(1-amino-1-oxo—3-phenylpropan17 2-yl)–1–(5-fluoropentyl)–1H-indazole-3-carboxamide. 

18 ‘‘(MMMM) methyl (1–(cyclohexylmethyl)–1H19 indazole-3-carbonyl-L-valinate. 

20 ‘‘(NNNN) N-[(1–(cyclohexylmethyl)–1H-inda21 zole-3yl)carbonyl]-3-methyl-L-valine, methyl ester. 

22 ‘‘(OOOO) methyl 2–(1–(cyclohexylmethyl)–1H23 indole-3-carboxamido)–3,3-dimethylbutanoate. 

24 ‘‘(PPPP) (1–(5-fluoropentyl)–1H25 benzo[d]imidazole-2-yl)(naphthalene-1-yl)methanone. 


SSpencer on DSK4SPTVN1PROD with BILLS
20 

•HR 3537 IH

1 ‘‘(QQQQ) (1–(4-fluorobenzyl)–1H-indol-3- 

2 yl)(napthalen-1-yl)methanone. 

3 ‘‘(RRRR) methyl 2–(1–(4-fluorobenzyl)–1H-in4 dazole-3-carboxamido)–3,3-dimethylbutanoate. 

5 ‘‘(SSSS) quinolin-8-yl 1–(4-fluorobenzyl)–1H6 indazole-3-carboxylate. 

7 ‘‘(TTTT) N–(adamantan-1-yl)–1–(4- 

8 fluorobenzyl)–1H-indazole-3-carboxamide. 

9 ‘‘(UUUU) N–(1-amino-3-methyl-1-oxobutan-2- 

10 yl)–1–(5-fluoropentyl)–1H-indole-3-carboxamide. 

11 ‘‘(VVVV) 2-[(1S,3R)–3-hydroxycyclohexyl]-5– 

12 (2-methylheptyl-2-yl)phenol. 

13 ‘‘(WWWW) 2-[(1S,3R)–3-hydroxycyclohexyl]-5– 

14 (2-methyldodecanyl-2-yl)phenol. 

15 ‘‘(XXXX) 3-hydroxy-2[3-methyl-6–(1- 

16 methylethyenyl)–2-cyclohexen-1-yl]-5-pentyl-2,5- 

17 cyclohexadiene-1,4-dione. 

18 ‘‘(YYYY) 4-[4–(1,1-dimethylheptyl)–2,6- 

19 dimethoxyphenyl]-6,6-dimethyl-bicyclo[3.1.1]hept-2- 

20 ene-2-methanol. 

21 ‘‘(ZZZZ) 1-naphthalenyl[4–(pentylox)–1- 

22 naphthalenyl]-methanone. 

23 ‘‘(AAAAA) 3–(2–(hydroxymethyl)–2,3-dihydro24 1H-inden-4-yloxy)phenyl 4,4,4-trifluorobutane-1- 

25 sulfonate. 


SSpencer on DSK4SPTVN1PROD with BILLS
21 

•HR 3537 IH

1 ‘‘(BBBBB) N–(benzo[1,3]dioxol-5-ylmethyl)–7- 

2 methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3- 

3 carboxamide. 

4 ‘‘(CCCCC) N-[3–(2-methoxyethyl)–4,5- 

5 dimethylthiazol-2-ylidene]-2,2,3,3- 

6 tetramethylcyclopropane-carboxamide. 

7 ‘‘(DDDDD) 5-chloro-3-ethyl-N-[4–(piperidin-1- 

8 yl)phenethyl)–1H-indole-2-carboximide. 

9 ‘‘(EEEEE) N-[4–(dimethylamino)phenethyl]-3- 

10 ethyl-5-fluoro-1H-indole-2-carboximide. 

11 ‘‘(FFFFF) N–(1-benzylpyrrolidin-3-yl)–5- 

12 chloro-3-ethyl-1H-indole-2-carboxamide. 

13 ‘‘(GGGGG) [5–(2-fluorophenyl)–1-pentyl-1H14 pyrrol-3-yl](naphthalene-1-yl)methanone. 

15 ‘‘(HHHHH) (3’-(aminocarbonyl)[1,1’-biphenyl]- 

16 3-yl)-cyclohexyl-carbamate. 

17 ‘‘(IIIII) 5–(biphenyl-4-ylmethyl)–N,N-dimethyl18 1H-tetrazole-1-carboxamide. 

19 ‘‘(JJJJJ) 6-methyl-2–(p-tolylamino)–4H20 benzo[d][1,3]oxazin-4-one. 

21 ‘‘(KKKKK) [1,1’-biphenyl]-3-yl-carbamic acid, 

22 cyclohexyl ester. 

23 ‘‘(LLLLL) 4-hydroxy-N–(4-hydroxyphenethyl)– 

24 3–(pentylamino)-benzamide. 


SSpencer on DSK4SPTVN1PROD with BILLS
22 

•HR 3537 IH

1 ‘‘(MMMMM) 3’-carbamoyl-6-hydroxy-[1,1’- 

2 biphenyl]-3-yl cyclohexylcarbamate. 

3 ‘‘(4) ARYLCYCLOHEXAMINES.—The substances listed 

4 in this paragraph consist of the following 

5 arylcyclohexamines: 

6 ‘‘(A) 1–(3-methoxyphenyl)–N-propylcyclohexan7 amine. 

8 ‘‘(B) 2–(ethylamino)–2–(3- 

9 methoxyphenyl)cyclohexanone. 

10 ‘‘(C) 1-phenylcyclohexan-amine. 

11 ‘‘(D) 1-[1–(benzothiophen-2- 

12 yl)cyclohexyl]piperidine. 

13 ‘‘(E) 1–(1-p-tolylcyclohexyl)-piperidine. 

14 ‘‘(F) 1–(4-methoxyphenyl)–N-propylcyclohexan15 amine. 

16 ‘‘(G) 1-[1–(4-methoxyphenyl)cyclohexyl]-piper17 idine. 

18 ‘‘(H) 1-[1–(3-methoxyphenyl)cyclohexyl]-piper19 idine. 

20 ‘‘(I) 1-phenyl-N-propylcyclohexanamine. 

21 ‘‘(J) N–(2-methoxyethyl)–1-phenylcyclohexan22 amine. 

23 ‘‘(K) N–(2-ethoxyethyl)–1-phenylcyclohexan24 amine. 


SSpencer on DSK4SPTVN1PROD with BILLS
23 

•HR 3537 IH

1 ‘‘(L) N–(3-methoxypropyl)–1-phenylcyclohexan2 amine. 

3 ‘‘(M) 3-[1–(piperidin-1-yl)cyclohexyl]-phenol. 

4 ‘‘(N) 2–(methoxyphenyl)–2– 

5 (methylamino)cyclohexanone. 

6 ‘‘(O) N-ethyl-1–(thiophen-2-yl)cyclohexanamine. 

7 ‘‘(P) (2–(2-chlorophenyl)–2–(ethylamino)- 

8 cyclohexanone). 

9 ‘‘(5) TRYPTAMINES.—The substances listed in this 

10 paragraph consist of the following tryptamines: 

11 ‘‘(A) 2–(1H-indol-3-yl)–N-methyl-ethanamine. 

12 ‘‘(B) N–(2–(1H-indol-3-yl)ethyl-N13 methylpropan-2-amine. 

14 ‘‘(C) N-[2–(1H-indol-3-yl)ethyl]-N15 isopropylpropan-2-amine. 

16 ‘‘(D) N,N-dipropyl-1H-indole-3-ethanamine. 

17 ‘‘(E) 3-[2–(diethylamino)ethyl]-1H–4yl acetate. 

18 ‘‘(F) 3–(2-[isopropyl(methyl)amino]ethyl)–1H19 indol-4-ol. 

20 ‘‘(G) 3-[2–(bis[1-methylethyl]amino)ethyl]-1H21 indol-4-ol acetate. 

22 ‘‘(H) 3–(2-[isopropyl(methyl)amino]ethyl)–1H23 indol-4-ol acetate. 

24 ‘‘(I) 3-[2–(dimethylamino)ethyl]-1H-indol-4-yl 

25 acetate. 


SSpencer on DSK4SPTVN1PROD with BILLS
24 

•HR 3537 IH

1 ‘‘(J) 4-hydroxy-N,N-diethyl-1H-indole2 ethanamine. 

3 ‘‘(K) 4-methoxy-N,N-dimethyl-1H-indole-3- 

4 ethanamine. 

5 ‘‘(L) 3–(2–(diisopropylamino)ethyl)–1H-indol-4- 

6 ol. 

7 ‘‘(M) 3-[2–(ethyl[methyl]amino)ethyl]-1H-indol8 4-ol. 

9 ‘‘(N) 3-[2–(ethyl[methyl]amino)ethyl]-1H-indol10 4-yl acetate. 

11 ‘‘(O) 3–(2–(dipropylamino)ethyl)–1H-indol-4-ol. 

12 ‘‘(P) 3-[2–(dipropylamino)ethyl]-1H-indol-4-yl 

13 acetate. 

14 ‘‘(Q) 4-acetoxy-N,N-di-2-propen-1-yl-1H-indole15 3-ethanamine. 

16 ‘‘(R) 5-methoxy-N,N-di-2-propen-1-yl-1H17 indole-3-ethanamine. 

18 ‘‘(S) 3–(2–(dimethylaminoethyl)–1H-indol-5-ol. 

19 ‘‘(T) 2–(5-methoxy-1H-indol-3-yl)–N,N20 dimethylethanamine. 

21 ‘‘(U) N-[2–(5-methoxy-1H-indol-3-yl)ethyl]-N22 methylpropyl. 

23 ‘‘(V) 1–(5-methoxy-1H-indol-3-yl)propan-2- 

24 amine. 


SSpencer on DSK4SPTVN1PROD with BILLS
25 

•HR 3537 IH

1 ‘‘(W) 3-[2–(dimethylamino)-ethyl]-1H-indol-5-yl 

2 acetate. 

3 ‘‘(X) N-[2–(5-methoxy-1H-indol-3-yl)ethyl]-N4 propylpropan-1-amine. 

5 ‘‘(Y) N,N-diethyl-2–(5-methoxy-1H-indol-3- 

6 yl)ethanamine. 

7 ‘‘(Z) N-ethyl-2–(5-methoxy-1H-indol-3-yl)–N8 methyl-ethanamine. 

9 ‘‘(6) BENZYLPIPERIDINES.—The substances listed in 

10 this paragraph consist of the following benzylpiperidines: 

11 ‘‘(A) 2–(diphenylmethyl)-piperidine. 

12 ‘‘(B) 2-benzhydrylpyrrolidine. 

13 ‘‘(C) a,a-diphenyl-(pyrrolidin-2-yl)methanol. 

14 ‘‘(D) methyl 2–(3,4-dichlorophenyl)–2– 

15 (piperdin-2-yl)acetate. 

16 ‘‘(E) methyl 2–(3-chlorophenyl)–2–(piperidin-2- 

17 yl)acetate. 

18 ‘‘(F) methyl 2–(piperidin-2-yl)–2-p-tolylacetate. 

19 ‘‘(G) methyl 2–(4-fluorophenyl)–2–(piperidin-2- 

20 yl)acetate. 

21 ‘‘(H) ethyl 2-phenyl-2–(piperidin-2-yl)acetate. 

22 ‘‘(7) BENZODIAZEPINES.—The substances listed in 

23 this paragraph consist of the following benzodiazepines: 

24 ‘‘(A) 4–(2-chlorophenyl)–2-ethyl-9-methyl-6H25 thieno-[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine. 


SSpencer on DSK4SPTVN1PROD with BILLS
26 

•HR 3537 IH

1 ‘‘(B) 7-bromo-5–(2-chlorophenyl)–1H2 benzo[e][1,4]diazepin-2(3H)-one. 

3 ‘‘(C) 8-bromo-1-methyl-6-phenyl-4H4 [1,2,4]triazolo[4,3a][1,4]benzodiazepine. 

5 ‘‘(D) 3-methyl-6-[3– 

6 (trifluoromethyl)phenyl][1,2,4]triazol[4,3- 

7 b]pyridazine. 

8 ‘‘(E) 6–(5-chloro-2-pyridyl)–6,7-dihydro-7-oxo9 5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1- 

10 carboxylate. 

11 ‘‘(8) OPIOIDS AND OPIOID-LIKE SUBSTANCES.—The 

12 substances listed in this paragraph consist of the following 

13 opioids and opioid-like substances: 

14 ‘‘(A) 2–(1,3-dimethoxybuta-1,3-dien-2-yl)–3- 

15 ethyl-8-methoxy-1,2,3,4,6,7,12,12b16 octahydroindolo[2,3-a]quin olizine. 

17 ‘‘(B) (2a,4aR,6aR,7R,9S,10aS10bR)-methyl-9- 

18 acetoxy-2–(furan-3-yl)–6a,10b-dimethyl-4,10- 

19 dioxododecahydro-1 H-benzo[f]isochromene-7- 

20 carboxylate. 

21 ‘‘(C) 3,4-dichloro-N–([1– 

22 (dimethylamino)cyclohexyl]methyl)benzamide. 

23 ‘‘(D) 3-[2–(amino-1-methylethyl)–1- 

24 hydroxycyclohexyl]-phenol. 

25 ‘‘(E) 4,5-epoxy-17-methylmorphinan-3-ol. 


SSpencer on DSK4SPTVN1PROD with BILLS
27 

•HR 3537 IH

1 ‘‘(F) N-phenyl-N-[1–(2-phenethyl)–4- 

2 piperidinyl] acetamide. 

3 ‘‘(G) N–(1-benzylpiperidin-4-yl)–N–(x4 fluorophenyl)-butanamide. 

5 ‘‘(H) 2-methyl-N-phenyl-N-[1–(1-phenylpropan6 2-yl)piperidin-4-yl]propanamide. 

7 ‘‘(I) N–(1-phenethylpiperidin-4-yl)–N8 phenylbutyramide. 

9 ‘‘(J) 1-cyclohexyl-4–(1,2-diphenylethyl)-piper10 azine. 

11 ‘‘(K) N-phenyl-N–(1–(2–(thiophen-2- 

12 yl)ethyl)piperidin-4-yl)acetamide. 

13 ‘‘(L) 4-chloro-N–(1-phenethylpiperidin-2- 

14 ylidene)benzenesulfonamide. 

15 ‘‘(M) 4-chloro-N–(1–(4- 

16 nitrophenethyl)piperidin-2- 

17 ylidene)benzenesulfonamide. 

18 ‘‘(9) PIPERAZINES.—The substances listed in this 

19 paragraph consist of the following piperazines: 

20 ‘‘(A) 1,4-dibenzylpiperazine. 

21 ‘‘(B) 1–(4-bromo-2,5-dimethoxybenzyl)-piper22 azine. 

23 ‘‘(C) 1–(4-fluorophenyl)-piperazine. 

24 ‘‘(D) 1–(2-methoxyphenyl)-piperazine. 

25 ‘‘(E) 1–(4-chlorophenyl)-piperazine. 


SSpencer on DSK4SPTVN1PROD with BILLS
28 

•HR 3537 IH

1 ‘‘(F) 1–(4-methoxyphenyl)-piperazine. 

2 ‘‘(G) 1–(3-methylbenzyl)piperazine. 

3 ‘‘(H) 1-benzyl-4-methylpiperazine. 

4 ‘‘(10) TROPANE ALKALOIDS.—The substances listed 

5 in this paragraph consist of the following tropane alka6 loids: 

7 ‘‘(A) 8-methyl-8-azabicyclo[3.2.1]octan-3-yl 4- 

8 fluorobenzoate. 

9 ‘‘(B) methyl 3–(4-fluorophenyl)–8-methyl-8- 

10 azabicyclo[3.2.1]octane-2-carboxylate.’’. 

11 (b) EFFECTIVE DATE.—The amendment made by 

12 subsection (a) takes effect on the date that is 30 days 

13 after the date of enactment of this Act. 

Æ 


SSpencer on DSK4SPTVN1PROD with BILLS