Exhibit 4.21







CONFIDENTIAL







THE SYMBOL "[****]" DENOTES PLACES
WHERE PORTIONS OF THIS DOCUMENT HAVE BEEN OMIITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT. SUCH MATERIAL HAS BEEN FILED
SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION



MASTER AGREEMENT WORK ORDER

AMENDMENT #1



Protocol # RHB-104-01 (MAP and Other Analysis)



Effective Date: date of last signature below



RedHill Biopharma

21 Ha’arba’a St.

Tel-Aviv Israel 64739



WHEREAS, RedhIll Biopharma Ltd. and Quest Diagnostics Clinical Laboratories, Inc. are
parties (together the “Parties”) to a Clinical Trials Global Master Services Agreement dated 27-December-2015 (the
“Agreement”) and have also entered into a Work Order on 10-Oct-2013 pursuant to Protocol RHB-104-01 (the “Work
Order”).



WHEREAS, Quintiles Laboratories and Quest Diagnostics have formed the company Q Squared
Solutions (Quest) LLC, to provide certain laboratory services (including central and bio-analytical laboratory services).



WHEREAS, pursuant to the joint venture described in the above recital, Q Squared Solutions
(Quest) LLC will hereinafter perform the Services under the Agreement, and all references to Quest Diagnostics Clinical Laboratories,
Inc. in the Agreement, the Work Order and this Amendment #1 shall reflect Q Squared Solutions (Quest) LLC (hereinafter “Q
Squared”) following the effective date of this Amendment.



NOW THEREFORE, the Parties agree as follows:



1.The purpose of this Amendment #1 to the Work Order is to revise the budget, update the project term and to provide services
by Q Squared Solutions.



2.The Term of the Agreement shall now be as follows:

Effective Date: 10-Oct-2013 End Date: [****]



| | 3. | The Budget has been updated to reflect :
| | -- | ----------------------------------------

| | · | the addition of Australia and New Zealand;
| | - | ------------------------------------------

| | · | an estimate for optional [****]use in the US only;
| | - | --------------------------------------------------

| | · | the addition of [****];
| | - | -----------------------

| | · | updated [****], [****], [****]
| | - | ------------------------------

| | · | that Israel and [****]shipping costs from sites direct [****]have
been line itemed until Quest is notified to begin shipping directly and the budget will be updated with these costs at that time;
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

| | · | outbound shipping of [****]is included - estimating [****]per
site;
| | - | -------------------------------------------------------------------

| | · | the inclusion of[****];
| | - | -----------------------

| | · | the addition of [****]: [****], [****], [****], [****],
[****], [****];
| | - | -----------------------------------------------------------------------

| | · | additional updates made to [****], [****] per client request;
| | - | -------------------------------------------------------------

| | · | the addition of [****]
| | - | ----------------------





RedHill Biopharma LimitedProtocol # RHB-104-01Master Agreement Work Order, Amendment #1Page 1 of 3








| | · | and a revised [****] sample volume;
| | - | -----------------------------------

| | · | add [****]([****]sites/[****]
screen/[****] randomized);
| | - | --------------------------------------------------------

| | · | remove [****] patients from [****]to move to [****];
| | - | ----------------------------------------------------

| | · | update visit names;
| | - | -------------------

| | · | study amendment fee;
| | - | --------------------

| | · | update to [****];
| | - | -----------------

| | · | [****];
| | - | -------

| | · | [****];
| | - | -------

| | · | Add [****], [****]to be sent to [****];
| | - | ---------------------------------------

| | · | change to [****];
| | - | -----------------

| | · | New kit for [****];
| | - | -------------------

| | · | costs added for [****];
| | - | -----------------------

| | · | extend DNA storage length to 10 years.
| | - | --------------------------------------



4. The revised Estimated Central Laboratory Budget is attached hereto as Attachment #1,
is incorporated herein by reference, and shall replace the Attachment #1 of the Work Order.



5. The study value is revised as follows:



|Document            | Change Value | Total Study
        Contracted Value*
|------------------- | ------------ | -------------------------------------
|Original Work Order | $0.00        | $[****]                              
|Amendment #1        | $[****]      | $[****]                              



*RedHill shall be invoiced for actual tests performed and services
rendered.



6. All other terms and conditions of the Work Order and the Clinical Trials Global Master
Services Agreement (the “Agreement”) shall remain in full force and effect. In the event of any conflict between the
terms of the Agreement, the Work Order, and this Amendment, the terms of this Amendment shall control.



7. The parties hereto agree to this Amendment #1 as of the effective date by authorized
signature below.





|REDHILL BIOPHARMA LIMITED               |  | Q Squared Solutions (Quest) LLC | 
|--------------------------------------- |  | ------------------------------- | 
|                                        |  |                                 | 
|                                        |  |                                 | 
|/s/ Dror Ben Asher     /s/ Ori Shilo    |  | /s/ Terrence D. Burke           | 
|Authorized Signature                    |  | Terrence D Burke                | 
|                                        |  | Authorized Person               | 
|Dror Ben-Asher               Ori Shilo  |  |                                 | 
|Name Printed                            |  |                                 | 
|                                        |  |                                 | 
|CEO                          Deputy CEO |  |                                 | 
|Title                                   |  |                                 | 
|                                        |  |                                 | 
|December 29, 2015                       |  | December 30, 2015               | 
|Date                                    |  | Date                            | 







RedHill Biopharma LimitedProtocol # RHB-104-01Master Agreement Work Order, Amendment #1Page 2 of 3




Attachment # 1

Protocol # RHB-104-01 (MAP and Other Analysis)











[The Quest Diagnostics Budget Version #16, dated 2-Sep-2015, is attached
hereto, is incorporated herein, contains 27 printed pages, and shall be printed in full for contract signature]































RedHill Biopharma LimitedProtocol # RHB-104-01Master Agreement Work Order, Amendment #1Page 3 of 3








CONFIDENTIAL









| |  | 
| |  | 
| |  | 
| |  | 







Q2 Solutions, a Quintiles Quest Joint Venture

Central
Laboratory Services Budget





Q2 Solutions, a Quintiles Quest Joint Venture (JV), brings together the clinical trials laboratory operations of the two parent organizations to provide biopharmaceutical customers with the diverse capabilities and end-to-end services required in the rapidly evolving biopharmaceutical industry.  The new organization creates a global laboratory network that combines Quintiles’ scale, clinical trial expertise, and diverse therapeutic experience with Quest Diagnostics’ operational, scientific and quality excellence, supply-chain network and informatics to promote greater innovation, quality and  value for biopharmaceutical customers.







RedHill Biopharma Limited

RHB-104-01 (CR)

Version 16

2-Sep-15









|              |        |        |       
|------------- | ------ | ------ | ------
|              |        |        |       
|Prepared for: | [****] | by:    | [****]
|              | [****] |        | [****]
|              | [****] |        | [****]
|              | [****] |        | [****]
|              | [****] |        | [****]
|              |        |        | [****]
|              |        |        |       
|              |        |        |       
|Tel:          | [****] | Tel:   | [****]
|              |        | Fax:   | [****]
|Email:        | [****] | Email: | [****]
























| |  | 
| |  | 
| |  | 
| |  | 





|2-Sep-15                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                   
|------------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|                                                                                                                          |                                                                                                                                                                                                                                                                                                                                                                                                                   
|Patrick L. McLean                                                                                                        
|Product Manager                                                                                                          
|RedHill Biopharma Limited                                                                                                
|21 Ha’arba’a St.                                                                                                         
|Tel-Aviv  Israel  64739                                                                                                  
|                                                                                                                          |                                                                                                                                                                                                                                                                                                                                                                                                                   
|                                                                                                                          |                                                                                                                                                                                                                                                                                                                                                                                                                   
|Regarding:                                                                                                                | Centralized Clinical Laboratory and Related Support Services for Protocol                                                                                                                                                                                                                                                                                                                                         
|                                                                                                                          | RHB-104-01 (CR)                                                                                                                                                                                                                                                                                                                                                                                                   
|                                                                                                                          |                                                                                                                                                                                                                                                                                                                                                                                                                   
|Dear Patrick :                                                                                                            |                                                                                                                                                                                                                                                                                                                                                                                                                   
|                                                                                                                          |                                                                                                                                                                                                                                                                                                                                                                                                                   
|Thank you for the opportunity to submit a revised budget for your study. This budget
    includes the  following changes.
|                                                                                                                          |                                                                                                                                                                                                                                                                                                                                                                                                                   
|                                                                                                                          | version16:
- add [****] ([****] sites/[****] screen/[****] randomized)- remove [****] patients from US to move to [****]- update visit names- study amendment fee: update to [****], Initial [****] receiving reported
as [****].  Remaining [****] to be [****], add [****], AUS/NZ MAP to be sent to [****],[****], New kit for [****] collection- costs added for [****]- extend DNA storage length to 10 years



Q2Solutions,
a Quintiles Quest Joint Venture has a commitment to peak performance, superior value for our customers, teamwork, innovation
and integrity.  We look forward to the opportunity to work with you todemonstrate our dedication to these
values.





If you have any questions or require further assistance, please feel free to call me.





Yours sincerely,













[****]



Senior Strategic Account Executive

Q2 Solutions, a Quintiles Quest Joint Venture


















|RedHill Biopharma Limited | Quote for Services                                                                                           | 
|------------------------- | ------------------------------------------------------------------------------------------------------------ | 
|                          |                                                                                                              | 
|                          | Assumptions
                                                                       Protocol: RHB-104-01 (CR) | 







Assumptions:





Global Phase III trial

[****] countries, [****] sites: Israel: [****] sites, US/Canada: [****] sites, AUS:  [****],
NZ:  [****], respectively, [****]:  [****] sites, [****]:  [****] sites
[****] screened , [****] baseline to visit [****], and decreasing number of patients from visit [****] to visit [****]

Recommended couriers:
Israel-  sites to [****], sites to Quest ([****],[****] and [****]and [****]),
[****]-  sites to [****] ([****],[****]), sites to Quest [****] ([****], [****] and [****] and [****]),
[****]-  sites to [****] ([****], [****]), sites to Quest [****] ([****], [****]and [****] and [****]),
Canada - sites to [****] ([****] and [****]), sites to Quest [****] ([****] and [****]),
US- sites to [****] ([****]), sites to Quest [****] ([****]),
Quest [****]
[****] to Quest US- [****] ([****])
Courier mapping- [****],[****],[****]:
Sites to Quest [****],
Sites to Quest [****], [****], [****].
Sites to Quest [****], [****].
Sites to [****]
Quest UK to [****], [****]
Courier mapping- [****] /Australia/New Zealand
Sites to Quest [****]
Sites to Quest [****], [****], [****].
Sites to [****]
Sites to [****], [****].
[****] to Quest [****]

Inbound budget (shipments from sites to Quest Diagnostics): [****], [****]

[****], [****].

PK [****]
PK [****], [****].
Worst case scenario: we assume [****] to be revised in accordance to validation data.
PK [****]

HIV Western Blot- we assume [****]

[****]:
1- [****],
2- [****],
3- [****],
4- [****],
5- [****].

[****]

Stored specimen:
For bidding purpose, we assume average storage of [****]. [****].
DNA extraction samples are due to be stored for 10 years.
Note: RedHill Biopharma is charged for rendered services only.

[****]-
[****] ([****], [****]) [****].
[****].
[****]
[****]
[****]
[****]



Week-end shipments from sites - [****]
EWP(extreme weather packaging)-[****].

Australia andNew Zealand supplies are sourced from the
US, these quantities are reflected in US region.



- [****]:
- [****]sites ([****] Aust, [****] NZ)
- [****]total visits plus ET
- [****] Enrolled ([****] total patient visits)
- supplies are sourced locally





Forceps can only be shipped in US; remaining countries will be sourced locally by RHB.












|RedHill Biopharma Limited | Quote for Services                                                                                                       | 
|------------------------- | ------------------------------------------------------------------------------------------------------------------------ | 
|                          |                                                                                                                          | 
|                          | Change In Scope History
                                                                       Protocol: RHB-104-01 (CR) | 







|Category                                          | Updated Study Value | Previous Study Value * | Difference | Comments                                                                                                                                                                                         
|------------------------------------------------- | ------------------- | ---------------------- | ---------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|Laboratory
    Testing                            | $[****]             | $[****]                | $[****]    | Addition of [****] patients ([****]
    screened/[****] randomized/[****] completed):  total of [****] additional patient visits                                                                 
|Supplies                                          | $[****]             | $[****]                | $[****]    | EU supplies increase of [****]%
    to account for [****] patients.                                                                                                                              
|Additional
    Pass-Through Services              | $[****]             | $[****]                | $[****]    | Reduction in US weekend shipments for patients that moved under
    [****]:-$[****][****]budget:  $[****][****] outbound sample shipping:  $[****][****] weekend shipments:  $[****]             
|Study
    Management                              | $[****]             | $[****]                | $[****]    | Capture all amendment charges:
    - update to [****]- add [****]- change to AUS/NZ [****] to [****]- change to [****]- New kit for [****]Per visit quantities updated to capture [****] patients
|Storage
    & Services                            | $[****]             | $[****]                | $[****]    | [****]                                                                                                                                                                                           
|Inbound
    Transportation                        | $[****]             | $[****]                | $[****]    | Adjustment to account for [****]
    shipping                                                                                                                                                    
|Batched
    Inbound                               | $[****]             | $[****]                | $[****]    | Adjustment to account for [****]
    shipping                                                                                                                                                    
|Outbound
    Transportation                       | $[****]             | $[****]                | $[****]    | Adjustment to account for [****]
    shipping                                                                                                                                                    
|Outbound
    Transportation - Shipping Containers | $[****]             | $[****]                | $[****]    | Adjustment to account for [****]
    shipping                                                                                                                                                    
|Estimated
    Central Laboratory Budget:          | $[****]             | $[****]                | $[****]    |                                                                                                                                                                                                  







* Budget taken from RedHill Biopharma Limited:  RHB-104-01 (CR).v15







|Date      | Reason                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               | Total Value | Difference | 
|--------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | ----------- | ---------- | 
|31-Oct-11 | Original                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             | $[****]     | $[****]    | 
|14-Nov-11 | Version2
    reflects the amended protocol (28October 2011)-  MAP testing and Chemistry/Hematology/Inflammatory markers/Urinalysis/Other
    AP markers                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              | $[****]     | $[****]    | 
|24-Nov-11 | version3:
    updated MAP testing processes/pricing, increasing number of MAP tests, expanded stool culture COP panel (addition of [****]
    agents: [****])                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        | $[****]     | $[****]    | 
|21-Dec-11 | version4:
    MAP validations/testing and other analysis[****]: revised countries:patients distribution for USA, Canada versus Israel resulting in a
    grand total of [****] screned/ week26-week[****] patients in North America and [****] patients in EuropeCombined shipments(ambient/frozen) at screening, [****] and [****]Updated selection of couriers in Canada and US for ambient shipments with [****] and Quest courier
    respectively                                                                                                                                                                                                                                                                                                                                                                               | $[****]     | $[****]    | 
|11-Jan-12 | Version
    5:  Updated discounting in testing and study management section.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         | $[****]     | $[****]    | 
|29-Aug-12 | version6
    reflects
    Protocol dated 22-Aug-2012
    Updated country:site:visit:patient distribution.
    3 countries, [****] sites, [****] screened/other visits patientsRoutine clinical laboratory tests (hematology, biochemistry, inflammatory markers and stool
    tests performed at Quest Diagnostics.Viral serology performed at screening visit.Urine pregnancy kits and urinalysis dipsticks to be supplies by Quest to sites[****]assay performed at Quest Diagnostics (frozen whole blood),Additional samples of [****]blood([****]) collected and frozen at weeks [****]. These samples
    will be retained at Quest Diagnostics during the course of the study for future MAP assessment.PK specimens managementCourier model as follow: (1) Combined shipments (ambient and frozen) at screening, [****] only. | $[****]     | $[****]    | 
|7-Mar-13  | version
    7 reflects FINAL protocol dated 20Feb2013
    All testing managed by Quest Diagnostics: safety, MAP testing and PK analysis.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             | $[****]     | $[****]    | 
|20-Mar-13 | version8
    captures study specs discussed on 20-March with RHB.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    | $[****]     | $[****]    | 
|15-Apr-13 | version9:
    
    PK analysis ([****]) done by a 3rd party located in Canada (confirmed by RHB 5-April);PK analysis ([****]) to be confirmed soon by RHB: testing AND validation fees as line items
    into this budget (zero quantity) - budget to be updated if QDCT eventually perform PK tissue analysis;validation fees( removed and to be included into the existing fully separate contract relating
    to MAP validations;no changes into the transportation budget ([****]s collected at the same time than other [****]samples).                                                                                                                                                                                                                                                                                        | $[****]     | $[****]    | 
|2-Sep-13  | version10
    captures the most recent decisions/information including notably the protocol amendment, approved [****],
    [****]for v, updated samples processes for Israel, US/Canada, special supplies.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          | $[****]     | $[****]    | 
|25-Sep-13 | version11-
    adjusted testing/aliquoting/storage mapping.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          | $[****]     | $[****]    | 
|8-Oct-13  | version
    12: Updated patients:visits distribution based on info dated 9-October (decreasing grand total number of patient-visits)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 | $[****]     | $[****]    | 
|5-Jun-14  | version13:  add
    Australia and New Zealand; add estimate for optional [****]use in US only.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       | $[****]     | $[****]    | 
|14-Nov-14 | version14:  
    add [****];update site numbers;[****]kits, starter packs and resupplies have been updated based on study amendments;Israel and [****] shipping costs from sites direct [****]have been line itemed until Quest is
    notified to begin shipping directly- budget to be updated with these costs at that time;outbound shipping of cooled [****] has also been included- estimate [****] shipments per site;[****]charge included as line item;add [****]                                                                                                                                                                                                                                                                                                                                                           | $[****]     | $[****]    | 
|15-Jan-15 | version15:
    - update site/visit/patient numbers per Patrick 19 Jan 2015,
    - addition of [****],- revised [****]volume of samples                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               | $[****]     | $[****]    | 
|18-Jun-15 | version16:
    [****]([****] sites/[****] screen/[****] randomized)- remove [****] patients from US to move to [****]- update visit names- study amendment fee: update to [****]results, [****]reported as[****].  [****]Remaining
    [****] related results to be [****], add [****], AUS/NZ MAP to be sent to [****], change to PK, New kit for calprotectin collection- costs added for [****]- extend DNA storage length to 10 years                                                                                                                                                                                                                                                                                                                                                                                            | $[****]     | $[****]    | 
























|RedHill Biopharma Limited | Quote for Services                                                                                              | 
|------------------------- | --------------------------------------------------------------------------------------------------------------- | 
|                          |                                                                                                                 | 
|                          | Budget Summary
                                                                       Protocol: RHB-104-01 (CR) | 







|Study Duration:        | [****] | Total Investigators:  | [****] | 
|---------------------- | ------ | --------------------- | ------ | 
|Quote Date:            | [****] | Total Countries:      | [****] | 
|Quote Expiration Date: | [****] | Total Visits:         | [****] | 
|                       |        | Total Patient-Visits: | [****] | 









|Estimated
    Grand Total Amount   | $[****] | 
|---------------------------------- | ------- | 
|Average Cost
    Per Patient-Visit | $[****] | 
|Average Cost
    Per Patient       | $[****] | 









Budget Summary1





|Sub-Totals                         | Region                     | Billing
    Amount         | Conversion
    Rate | Estimated
    Total Amount
|---------------------------------- | -------------------------- | -------------------------- | ------------------- | --------------------------
|                                   | USA,
    Canada            | $[****]                    | 1.0000              | $[****]                   
|* See
    Budget Summary_EU        | Israel,
    [****], [****] | $[****]                    | 1.0000              | $[****]                   
|                                   | Australia,
    New Zealand | $[****]                    | 1.0000              | $[****]                   
|                                   | Study
    Set-up Fees      | $[****]                    | 1.0000              | $[****]                   
|                                   |                            |                            |                     | $[****]                   
|Average
    Cost Per Patient-Visit | Region                     | Estimated
    Total Amount | Patient
    Visits  | Average
    Cost          
|                                   | USA,
    Canada            | $[****]                    | [****]              | $[****]                   
|                                   | Israel,
    [****], [****] | $[****]                    | [****]              | $[****]                   
|                                   | Australia,
    New Zealand | $[****]                    | [****]              | $[****]                   
|                                   | Study
    Set-up Fees      | $[****]                    |                     |                           
|                                   |                            | $[****]                    | [****]              | $[****]                   
|Average
    Cost Per Patient       | Region                     | Estimated
    Total Amount | Patients            | Average
    Cost          
|                                   | USA,
    Canada            | $[****]                    | [****]              | $[****]                   
|                                   | Israel,
    [****], [****] | $[****]                    | [****]              | $[****]                   
|                                   | Australia,
    New Zealand | $[****]                    | [****]              | $[****]                   
|                                   | Study
    Set-up Fees      | $[****]                    |                     |                           
|                                   |                            | $[****]                    | 270                 | $[****]                   







Detailed Budget
Summary







|Laboratory
    Testing                                     | Region                     | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount
|---------------------------------------------------------- | -------------------------- | ------------------ | ------------------- | --------------------------
|                                                           | USA, Canada                | $[****]            | 1.0000              | $[****]                   
|                                                           | Israel, [****],
    [****] | $[****]            | 1.0000              | $[****]                   
|                                                           | Australia, New Zealand     | $[****]            | 1.0000              | $[****]                   
|Laboratory Testing Total 1LT,3LT,5LT,6LT,7LT,8LT,9LT       |                            |                    |                     | $[****]                   
|Supplies                                                   | Region                     | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount
|                                                           | USA, Canada                | $[****]            | 1.0000              | $[****]                   
|                                                           | Israel, [****],
    [****] | $[****]            | 1.0000              | $[****]                   
|                                                           | Australia, New Zealand     | $[****]            | 1.0000              | $[****]                   
|Supplies Total *SL                                         |                            |                    |                     | $[****]                   
|Additional
    Pass-Through Services                       | Region                     | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount
|                                                           | USA, Canada                | $[****]            | 1.0000              | $[****]                   
|                                                           | Israel, [****],
    [****] | $[****]            | 1.0000              | $[****]                   
|                                                           | Australia, New Zealand     | $[****]            | 1.0000              | $[****]                   
|Additional Pass-Through Services
    Total                 |                            |                    |                     | $[****]                   
|Storage                                                    | Region                     | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount
|                                                           | USA, Canada                | $[****]            | 1.0000              | $[****]                   
|                                                           | Israel, [****],
    [****] | $[****]            | 1.0000              | $[****]                   
|                                                           | Australia, New Zealand     | $[****]            | 1.0000              | $[****]                   
|Storage Total  1ST,2ST,3ST                                 |                            |                    |                     | $[****]                   
|Study
    Management                                       | Region                     | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount
|                                                           | USA, Canada                | $[****]            | 1.0000              | $[****]                   
|                                                           | Israel, [****],
    [****] | $[****]            | 1.0000              | $[****]                   
|                                                           | Australia, New Zealand     | $[****]            | 1.0000              | $[****]                   
|                                                           | Study Set-up Fees          | $[****]            | 1.0000              | $[****]                   
|Study Management Total  1SM,2SM,3SM,4SM,5SM,6SM,7SM,8SM    |                            |                    |                     | $[****]                   
|Inbound
    Transportation                                 | Region                     | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount
|                                                           | USA, Canada                | $[****]            | 1.0000              | $[****]                   
|                                                           | Israel, [****],
    [****] | $[****]            | 1.0000              | $[****]                   
|                                                           | Australia, New Zealand     | $[****]            | 1.0000              | $[****]                   
|Inbound Transportation Total  1IT,2IT,3IT,**               |                            |                    |                     | $[****]                   
|Inbound
    Batched Shipments                              | Region                     | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount
|                                                           | USA, Canada                | $[****]            | 1.0000              | $[****]                   
|                                                           | Israel, [****],
    [****] | $[****]            | 1.0000              | $[****]                   
|                                                           | Australia, New Zealand     | $[****]            | 1.0000              | $[****]                   
|Inbound Batched Shipments Total  1IT,2IT,3IT,***           |                            |                    |                     | $[****]                   
|Outbound
    Transportation                                | Region                     | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount
|                                                           | USA, Canada                | $[****]            | 1.0000              | $[****]                   
|                                                           | Israel,[****], [****]      | $[****]            | 1.0000              | $[****]                   
|                                                           | Australia, New Zealand     | $[****]            | 1.0000              | $[****]                   
|Outbound Transportation Total  1OT,2OT,3OT,4OT,5OT,6OT,7OT |                            |                    |                     | $[****]                   
|Shipping
    Container Transportation                      | Region                     | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount
|                                                           | USA, Canada                | $[****]            | 1.0000              | $[****]                   
|                                                           | Israel, [****],
    [****] | $[****]            | 1.0000              | $[****]                   
|Shipping
    Container Transportation Total  5OT,6OT,7OT   |                            |                    |                     | $[****]                   






















|Fee
    Type                                      | Israel  | [****]  | [****]  | Total
    EU
|------------------------------------------------- | ------- | ------- | ------- | ------------
|Laboratory
    Testing                            | $[****] | $[****] | $[****] | $[****]     
|Supplies                                          | $[****] | $[****] | $[****] | $[****]     
|Special
    Services                              | $[****] | $[****] | $[****] | $[****]     
|Study
    Management                              | $[****] | $[****] | $[****] | $[****]     
|Storage
    & Services                            | $[****] | $[****] | $[****] | $[****]     
|Inbound
    Transportation                        | $[****] | $[****] | $[****] | $[****]     
|Batched
    Inbound                               | $[****] | $[****] | $[****] | $[****]     
|Outbound
    Transportation                       | $[****] | $[****] | $[****] | $[****]     
|Outbound
    Transportation - Shipping Containers | $[****] | $[****] | $[****] | $[****]     
|Estimated
    Central Laboratory Budget:          | $[****] | $[****] | $[****] | $[****]     














|RedHill Biopharma Limited | Quote for Services                                                                                              | 
|------------------------- | --------------------------------------------------------------------------------------------------------------- | 
|                          |                                                                                                                 | 
|                          | Detail Summary
                                                                       Protocol: RHB-104-01 (CR) | 













|Laboratory
    Testing                      | Region                 | Time
    Points | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|------------------------------------------- | ---------------------- | --------------- | --------- | ----------------------------------- | ------------------ | ------------------- | -------------------------- | --------------------- | ------------------------------------------------ | ----------------------------------- | ----------------------------
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | TBD                                 | TBD                | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | 1               | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Laboratory Testing Total                    |                        |                 |           |                                     |                    |                     | $[****]                    |                       |                                                  | $[****]                             | $[****]                     
|Supplies                                    | Region                 | Unit            | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      | USA, Canada            | CASE            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | CASE            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | BOX             | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | CASE            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | PACK            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | EACH            | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Supplies Total                              |                        |                 |           |                                     |                    |                     | $[****]                    |                       |                                                  | $[****]                             | $[****]                     
|Additional
    Pass-Through Services        | Region                 | Unit            | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Additional
    Pass-Through Services        | Region                 | Unit            | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      |                        |                 | [****]    |                                     |                    |                     |                            |                       |                                                  |                                     |                             
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Additional Pass-Through
    Services Total  |                        |                 |           |                                     |                    |                     | $[****]                    |                       |                                                  | $[****]                             | $[****]                     
|Storage                                     | Region                 | Aliquots        | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Storage                                     | Region                 | Aliquots        | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      | Israel, [****], [****] | [****]          | 413       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 9,499     | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 413       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 922       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | Line Item | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 922       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 121       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | Line Item | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 121       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | Line Item | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 1,219     | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 6,307     | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 6,307     | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 669       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 15,387    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 669       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 669       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 79,611    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 669       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 669       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 79,611    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 669       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 262       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 31,178    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 262       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 262       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 31,178    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 262       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 931       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 931       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 931       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 53        | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 262       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 262       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 922       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 922       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 922       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 121       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 121       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] | [****]          | 121       | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Storage                                     | Region                 | Aliquots        | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand | [****]          | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Storage Total                               |                        |                 |           |                                     |                    |                     | $[****]                    |                       |                                                  | $[****]                             | $[****]                     
|Study
    Management                        | Region                 | Unit            | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Study Set-up Fees      |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Study Set-up Fees      |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Study Set-up Fees      |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Study Set-up Fees      |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Study Management Total                      |                        |                 |           |                                     |                    |                     | $[****]                    |                       |                                                  | $[****]                             | $[****]                     
|Inbound
    Transportation                  | Region                 | Unit            | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Inbound Transportation
    Total            |                        |                 |           |                                     |                    |                     | $[****]                    |                       |                                                  | $[****]                             | $[****]                     
|Inbound
    Batched Shipments               | Region                 | Unit            | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Inbound Batched Shipments
    Total         |                        |                 |           |                                     |                    |                     | $[****]                    |                       |                                                  | $[****]                             | $[****]                     
|Outbound
    Transportation                 | Region                 | Unit            | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | [****]              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Australia, New Zealand |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Outbound Transportation
    Total           |                        |                 |           |                                     |                    |                     | $[****]                    |                       |                                                  | $[****]                             | $[****]                     
|Shipping
    Container Transportation       | Region                 | Unit            | Quantity  | Billing
    Currency
    Unit Price | Billing
    Amount | Conversion
    Rate | Estimated
    Total Amount | Previous
    Quantity | Previous
    Billing
    Currency
    Unit Price | Previous
    Estimated Total Amount | Estimated
    Total Variance
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | USA, Canada            |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|[****]                                      | Israel, [****], [****] |                 | [****]    | $[****]                             | $[****]            | 1.0000              | $[****]                    | [****]                | $[****]                                          | $[****]                             | $[****]                     
|Shipping Container Transportation
    Total |                        |                 |           |                                     |                    |                     | $[****]                    |                       |                                                  | $[****]                             | $[****]                     




















|RedHill Biopharma Limited | Quote for Services                                                                                                                                                                                                                | 
|------------------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | 
|                          |                                                                                                                                                                                                                                   | 
|                          | Test Visit Schedule
                                                                                               All Locations
                                                                       Protocol: RHB-104-01 (CR) | 

















[****]






















|RedHill Biopharma Limited | Quote for Services                                                                                                                                                                                                                   | 
|------------------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | 
|                          |                                                                                                                                                                                                                                      | 
|                          | Patient Visit Schedule
                                                                                               All Locations
                                                                       Protocol: RHB-104-01 (CR) | 



















|Country                                               | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|----------------------------------------------------- | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------ | ------
|Calculated Totals:                                    | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|                                                      | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|Canada (Toronto)                                      | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|United States (New York)                              | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|Israel (Tel Aviv)                                     | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|Israel (Tel Aviv) - sites direct to [****]            | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|Canada (Toronto) - sites direct to [****]             | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|United States (New York) - sites direct to
    [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|Australia ([****])                                    | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|Australia ([****]) - sites direct to [****]           | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|New Zealand ([****])                                  | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|New Zealand ([****]) - [****]                         | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|[****]                                                | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|[****]                                                | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|[****]                                                | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]
|[****]                                                | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****] | [****]






















|RedHill Biopharma Limited | Quote for Services                                                                                         | 
|------------------------- | ---------------------------------------------------------------------------------------------------------- | 
|                          |                                                                                                            | 
|                          | End Notes
                                                                       Protocol: RHB-104-01 (CR) | 







|Global Summary                                   
|-------------------------------------------------
|1                                                
|Global Summary - Laboratory Testing (LT)         
|1LT                                              
|2LT                                              
|3LT                                              
|4LT                                              
|5LT                                              
|6LT                                              
|7LT                                              
|8LT                                              
|9LT                                              
|Global Summary - Supplies
    (SL)               
|*                                                
|Global Summary - Storage (ST)                    
|1ST                                              
|2ST                                              
|3ST                                              
|Global Summary - Study Management
    (SM)       
|1SM                                              
|2SM                                              
|3SM                                              
|4SM                                              
|5SM                                              
|6SM                                              
|7SM                                              
|8SM                                              
|Global Summary - Inbound Transportation
    (IT) 
|**                                               
|***                                              
|1IT                                              
|2IT                                              
|3IT                                              
|Global Summary - Outbound
    Transportation (OT)
|1OT                                              
|2OT                                              
|3OT                                              
|4OT                                              
|5OT                                              
|6OT                                              
|7OT