# Support Documents for Significant New Use Rules (SNUR) on Premanufacture Notices (PMN)
P-05-714

EPA Docket EPA-HQ-OPPT-2012-0182

# Index A-001 Structure Activity Team (SAT) Report for PMN P-05-714 A-002 Initial Review Engineering Report for PMN P-05-714 A-003 Initial Review Exposure Report for PMN P-05-714

# A-001 Structure Activity Team (SAT) Report
for PMN P-05-714

### STRUCTURE ACTIVITY TEAM REPORT 19 August 2005

CASE NUMBER: P05-0714

RELATED CASES:

CONCLUSIONS/DISCUSSIONS

TYPE OF CONCERN: HEALTH ECOTOX

LEVEL: 1-2 3
KEYWORDS: LUNG, IRR-MM, AQUATOX-A,C

SUMMARY OF ASSESSMENT:

FATE:

liquid with mp = -2 C (M) S = dispersible at 25 C, pH 7 (P) vp < 1.0E-6 mm Hg or torr at 25 E C (P) H < 1.0E-8 (P) POTW removal = 50 to 90% via sorption and biodegradation time for complete ultimate aerobic biodegradation = weeks to months sorption to soils and sediments = moderate to strong PBT Potential: P1B1T1 *CEB FATE: migration to ground water = moderate to slow
HEALTH: Absorption nil all routes based on physical/chemical properties;
test data for analog, were: rat acute oral LD0 = 5.0 g/kg with no significant toxic signs; slight and transient (1 d) eye irritation in rabbits; slight and transient (7 d) skin irritation in rabbits;
concern for lung toxicity and irritation to mucous membranes due to the

low to moderate concern for toxicity. *CEB HEALTH: Exposures to humans: inhalation only
ECOTOX: Predicted (P) and measured (M) toxicity values in

### mg/L (ppm) are: fish 96-h LC50 =< 1.8 P daphnid 48-h LC50 =< 2.3 P green algal 96-h EC50 =< 0.360 P fish chronic value =< 0.100 P daphnid ChV =< 0.160 P algal ChV =< 0.100 P Predictions are based on SARs for

S = dispersible (P); pH7; effective concentrations based on 100% active ingredients and nominal concentrations; hardness < 150.0 mg/L as CaCO3; and TOC <2.0 mg/L; high concern as a worst case assessment factor = 10.0 concern concentration = 0.010 mg/L (ppm) *CEB ECOTOX: All releases to water with CC = 10 ppb
SAT co-chair: Vince Nabholz, 564.8909

# A-002 Initial Review Engineering Report
for PMN P-05-714

### INITIAL REVIEW ENGINEERING REPORT PMN: 05-0714 Focus Ready Draft 8/29/2005
ENGINEER: Macek \ AMO \ DGR PV (kg/yr):

SUBMITTER:

USE:

OTHER USES:

MSDS: Yes Label: No
Gen Eqpt: PVC or Neoprene gloves / goggles / protective clothing Respirator: not required Health Effects: irritant to skin, eyes, and mucous membranes TLV/PEL: none established

CRSS (08/18/2005): Chemical Name:

S-H20: Dispersible g/L @ VP: 1.0E-6 torr @ MW: Physical State and Misc CRSS Info:

Consumer Use: No
SAT (concerns) (08/19/2005): Migration to groundwater: Slow to moderate

### PBT rating: P1B1T1 Health: 1-2 Inhalation Eco: 3 Water (All releases to water with a CC = 10 ppb)

OCCUPATIONAL EXPOSURE RATING: 1-2D

NOTES & KEY ASSUMPTIONS: Generated by the 06/07/2005 version of ChemSTEER.

POLLUTION PREVENTION CONSIDERATIONS: None.

EXPOSURE-BASED REVIEW: No

INITIAL REVIEW ENGINEERING REPORT PMN: 05-0714
Processing:

Number of Sites/ Location: 100 unknown sites Days/yr: 14 Basis:

### Process Description:

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY IRER Note: The daily releases listed for any source below may coincide with daily releases from the other sources to the same medium. Air - negligible (VP < 0.01 torr).

Water or Incineration High End: 3.1E+0 kg/site-day over 2 days/yr from 100 sites or 6.2E+2 kg/yr

Water or Incineration Conservative: 1.8E-1 kg/site-day over 14 days/yr from 100 sites or 2.5E+2 kg/yr

RELEASE TOTAL 8.8E+2 kg/yr - all sites

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY Tot. # of workers exposed via assessed routes: 0 Basis:

Inhalation: negligible (liquid, VP < 0.001 torr, )

Dermal: not required by SAT.

### INITIAL REVIEW ENGINEERING REPORT PMN: 05-0714

Use 1:

Number of Sites/ Location: 400 unknown sites Days/yr: 250 Basis:

Process Description:

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY IRER Note: The daily releases listed for any source below may coincide with daily releases from the other sources to the same medium. Air - negligible (VP < 0.01 torr).

Water Output 2: 1.5E-1 kg/site-day over 250 days/yr from 400 sites to:

Water or Incineration or Landfill High End: 2.5E-2 kg/site-day over 60 days/yr from 400 sites or 6.0E+2 kg/yr

Water or Incineration or Landfill Conservative: 2.0E-3 kg/site-day over 250 days/yr from 400 sites or 2.0E+2 kg/yr

### RELEASE TOTAL 1.6E+4 kg/yr - all sites

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY Tot. # of workers exposed via assessed routes: 1,200 Basis:

Inhalation:
Exposure to Particulate (Class I) Upper Bound: 6.0E-1 mg/day over 250 days/yr Number of workers (all sites) with inhalation exposure: 1,200 Basis: EB assesses 3 worker/site (default). NOTE: The respirator class is: I. Particulate (including solid or liquid droplets).

INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2)a) Exposure level > 1 mg/day? No OR b) Hazard Rating for health of 2 or greater? 1-2 No Inhalation Monitoring Data Desired? No

Dermal: not required by SAT.

INITIAL REVIEW ENGINEERING REPORT PMN: 05-0714

Use 2:

Number of Sites/ Location: 106 unknown sites Days/yr: 250 Basis:

Process Description:

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY IRER Note: The daily releases listed for any source below may coincide with daily releases from the other sources to the same

### medium. Air - negligible (VP < 0.01 torr).

Water or Incineration or Landfill High End: 2.5E-2 kg/site-day over 28 days/yr from 106 sites or 7.4E+1 kg/yr

Water or Incineration or Landfill Conservative: 1.9E-3 kg/site-day over 250 days/yr from 106 sites or 5.0E+1 kg/yr

RELEASE TOTAL 1.2E+2 kg/yr - all sites

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY Tot. # of workers exposed via assessed routes: 0 Basis:

Inhalation: negligible (liquid, VP < 0.001 torr, )

Dermal: not required by SAT.

INITIAL REVIEW ENGINEERING REPORT PMN: 05-0714

Use 3:

Number of Sites/ Location: 1 unknown site Days/yr: 118 Basis:

### Process Description:

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY IRER Note: The daily releases listed for any source below may coincide with daily releases from the other sources to the same medium.

Water Output 2: 1.5E+0 kg/site-day over 118 days/yr from 1 site

Air Output 2: 6.4E-1 kg/site-day over 118 days/yr from 1 site

Landfill Output 2: 1.4E+1 kg/site-day over 118 days/yr from 1 site or 1.6E+3 kg/yr

RELEASE TOTAL 1.9E+3 kg/yr - all sites

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY Tot. # of workers exposed via assessed routes: 17 Basis:

Inhalation:
Exposure to Mist (non-volatile) (Class I) What-If: 3.7E-1 mg/day over 118 days/yr Number of workers (all sites) with inhalation exposure: 17 Basis:

NOTE: The respirator class is: I. Particulate (including solid or liquid droplets).

### INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2)a) Exposure level > 1 mg/day? No OR b) Hazard Rating for health of 2 or greater? 1-2 No Inhalation Monitoring Data Desired? No

Dermal: not required by SAT.

MEMORANDUM of CBI TELEPHONE CONVERSATION

CALL BY: Aaron Osborne Organization: ERG for EPA/OPPT/CEB

CALL TO:
Organization:

Date: 08/22/2005

Time: 8:30

Phone:

PMN: 05-0714

# A-003 Initial Review Exposure Report
for PMN P-05-714

### Chemical ID: P-05-0714 Reviewer: Delpire/BC
Partially updated exposure report for selected release scenarios (only) using updated SIC code stream flows and 2 Concentrations of Concern (5.6 ppb and 10 ppb).

Chemical ID: P-05-0714 Assessor: Delpire/BC

ENVIRONMENTAL RELEASES

Scenario#:1 Number of Release Sites: Release Activity:
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases: N/A N/A N/A (kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge Release Days/yr: 0.00/ 0.00 N/A N/A

Per Site Release: N/A/0.00 N/A N/A (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

### 12/28/2011 POSTFOCUS EXPOSURE REPORT Page 2 of 9

Chemical ID: P-05-0714

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 1 Number of Sites RELEASE ACTIVITY

SIC-CODE DESCRIPTION: SIC-CODE (S): EX POSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)
0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50 0.42 1.49 2.42 2.93

ALL 10 2.54 7.19 12.35 14.75

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units 50% 10% 50% 10%

Cancer

LADD pot 5.33E-07 3.26E-06 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 2.73E-05 1.67E-04 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 1.25E-04 6.01E-04 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:Chemical ID: P-05-0714

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 1 RELEASE ACTIVITY:

SIC CODE DES CRIPTION:

ASSOCIATED SIC CODES:

SIC CODE RESULTS

COC ( μ g/L) Percent of Year COC Exceeded Number of Days COC Exceeded Release days/year Loading (kg/site/day) Waste Water Treatment (%) High/Avg Analysis

5.60 1 4 60.00 50.00 High

10.00 0 2 60.00 50.00 HighChemical ID: P-05-0714 Assessor:

ENVIRONMENTAL RELEASES

Scenario#:2 Number of Release Sites Release Activity:
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases: N/A N/A N/A (kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge Release Days/yr: 250.00 0.00/0.00 N/A N/A

Per Site Release: N/A/0.00 N/A N/A (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks:

### 12/28/2011 POSTFOCUS EXPOSURE REPORT Page 5 of 9

Chemical ID: P-05-0714

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 2 Number of Site s: RELEASE ACTIVITY:USE 1b

SIC-CODE DESCRIPTION: SIC-CODE (S): EX POSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)
250. 0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50 0.35 1.24 2.02 2.44

ALL 10 2.12 6.00 10.29 12.30

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units 50% 10% 50% 10%

Cancer

LADD pot 1.85E-06 1.13E-05 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 9.49E-05 5.80E-04 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 1.04E-04 5.01E-04 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:Chemical ID: P-05-0714

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 2 RELEASE ACTIVITY: USE 1b

SIC CODE DES CRIPTION:

ASSOCIATED SIC CODES

SIC CODE RESULTS

COC ( μ g/L) Percent of Year COC Exceeded Number of Days COC Exceeded Release days/year Loading (kg/site/day) Waste Water Treatment (%) High/Avg Analysis

5.60 4 13 250.00 High

10.00 2 6 250.00 HighChemical ID: P-05-0714 Assessor:

ENVIRONMENTAL RELEASES

Scenario#:3 Number of Release Sites: Release Activity:
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases: N/A N/A N/A (kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge Release Days/yr: 0.00/ 0.00 N/A N/A

Per Site Release: N/A/0.00 N/A N/A (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks:

### 12/28/2011 POSTFOCUS EXPOSURE REPORT Page 8 of 9

Chemical ID: P-05-0714

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 3 Number of Site s: RELEASE ACTIVITY

SIC-CODE DESCRIPTION: SIC-CODE (S): EXPOSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)
118. 0 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50 2.67 5.74 9.07 11.03

ALL 10 53.84 86.21 150.00 178.57

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units 50% 10% 50% 10%

Cancer

LADD pot 6.73E-06 1.36E-04 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 3.45E-04 6.96E-03 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 4.80E-04 7.20E-03 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:Chemical ID: P-05-0714

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 3 RELEASE ACTIVITY:

SIC CODE DESCRIPTION:

ASSOCIATED SIC CODES:

SIC CODE RESULTS

COC ( μ g/L) Percent of Year COC Exceeded Number of Days COC Exceeded Release days/year Loading (kg/site/day) Waste Water Treatment (%) High/Avg Analysis

5.60 32 118 118.00 High

10.00 32 118 118.00 High