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                            Funding & Awards
 Denver Police Department, Crime Laboratory Bureau: Forensic DNA Research and Development - Sperm Capture Using Aptamer Based Technology
Award Information
Awardee
              City and County of Denver; Denver Police Department
Award #
              2009-DN-BX-K043
Funding Category
              Competitive
Location
                    Denver, CO
Congressional District
              1
Status
              Closed
Funding First Awarded
              2009
Total funding (to date)
              $405,812
Original Solicitation
              NIJ FY 09 Forensic DNA Research and Development: Invited Full Proposals
Description of original award (Fiscal Year 2009, $405,812)
Aptamers are single-stranded nucleic acid molecules with molecular recognition properties comparable to antibodies, although often with even higher specificity. The goal of this project is to develop an assay that uses aptamers to capture and separate spermatozoa found in sexual assault evidence prior to DNA extraction. The assay will allow for the immobilization of spermatozoa on a solid matrix, such as a coated 96-well plate, beads, or other suitable matrices. This sperm-capture assay can be automated for high-throughput processing and could therefore greatly decrease the amount of time required to develop male DNA profiles from sexual assault evidence in a cost effective manner. 

ca/ncf



  
Grant-Funded Publications
        
                      Sperm Cell Purification From Mock Forensic Swabs Using SOMAmer (TM) Affinity Reagents
                  Sperm Capture Using Aptamer Based Technology

  
Date Created: September 9, 2009
    
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