Support Documents for 

Significant New Use Rules (SNUR) on 

Premanufacture Notices (PMN) 

P-05-714 

EPA Docket EPA-HQ-OPPT-2012-0182 

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Index 

A-001 Structure Activity Team (SAT) Report for 

 PMN P-05-714 

A-002 Initial Review Engineering Report for 

 PMN P-05-714 

A-003 Initial Review Exposure Report for 

 PMN P-05-714 

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A-001 

Structure Activity Team (SAT) Report 

 for PMN P-05-714 

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STRUCTURE ACTIVITY TEAM REPORT 19 August 2005 

CASE NUMBER: P05-0714

RELATED CASES: 

CONCLUSIONS/DISCUSSIONS 

TYPE OF CONCERN: HEALTH ECOTOX

LEVEL: 1-2 3 

KEYWORDS: LUNG, IRR-MM, AQUATOX-A,C 

SUMMARY OF ASSESSMENT: 

FATE: 

liquid with mp = -2 C (M) 

S = dispersible at 25 C, pH 7 (P) 

vp < 1.0E-6 mm Hg or torr at 25 EC (P) 

H < 1.0E-8 (P) 

POTW removal = 50 to 90% via sorption and biodegradation 

time for complete ultimate aerobic biodegradation = weeks to 

months 

sorption to soils and sediments = moderate to strong 

PBT Potential: P1B1T1 

*CEB FATE: migration to ground water = moderate to slow 

HEALTH: Absorption nil all routes based on 

physical/chemical properties; 

test data for analog, were: 

rat acute oral LD0 = 5.0 g/kg with no significant toxic 

signs; 

slight and transient (1 d) eye irritation in rabbits; 

slight and transient (7 d) skin irritation in rabbits; 

concern for lung toxicity and irritation to mucous membranes 

due to the

low to moderate concern for toxicity. 

*CEB HEALTH: Exposures to humans: inhalation only 

ECOTOX: Predicted (P) and measured (M) toxicity values in 

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mg/L (ppm) are: 

fish 96-h LC50 =< 1.8 P 

daphnid 48-h LC50 =< 2.3 P 

green algal 96-h EC50 =< 0.360 P 

fish chronic value =< 0.100 P 

daphnid ChV =< 0.160 P 

algal ChV =< 0.100 P 

Predictions are based on SARs for 

 S = dispersible 

(P); pH7; effective concentrations based on 100% active 

ingredients and nominal concentrations; hardness < 150.0 

mg/L as CaCO3; and TOC <2.0 mg/L; 

high concern as a worst case 

assessment factor = 10.0 

concern concentration = 0.010 mg/L (ppm) 

*CEB ECOTOX: All releases to water with CC = 10 ppb 

SAT co-chair: Vince Nabholz, 564.8909 

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A-002 

Initial Review Engineering Report 

 for PMN P-05-714 

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INITIAL REVIEW ENGINEERING REPORT 

PMN: 05-0714

Focus Ready Draft 8/29/2005

ENGINEER: Macek \ AMO \ DGR

PV (kg/yr): 

SUBMITTER: 

USE:

OTHER USES:

MSDS: Yes Label: No

Gen Eqpt: PVC or Neoprene gloves / goggles / protective clothing

Respirator: not required

Health Effects: irritant to skin, eyes, and mucous membranes

TLV/PEL:

none established

CRSS (08/18/2005):

Chemical Name: 

S-H20: Dispersible g/L @

VP: 1.0E-6 torr @

MW: 

Physical State and Misc CRSS Info:

 

Consumer Use: No

SAT (concerns) (08/19/2005):

Migration to groundwater: Slow to moderate

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PBT rating: P1B1T1

Health: 1-2 Inhalation

Eco: 3 Water (All releases to water with a CC = 10 ppb)

OCCUPATIONAL EXPOSURE RATING: 1-2D

NOTES & KEY ASSUMPTIONS:

Generated by the 06/07/2005 version of ChemSTEER. 

 

POLLUTION PREVENTION CONSIDERATIONS:

None.

EXPOSURE-BASED REVIEW: No

INITIAL REVIEW ENGINEERING REPORT 

PMN: 05-0714

Processing: 

Number of Sites/ Location: 100

unknown sites

Days/yr: 14

Basis:

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Process Description: 

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY

IRER Note: The daily releases listed for any source below may

coincide with daily releases from the other sources to the same

medium. Air - negligible (VP < 0.01 torr).

Water or Incineration

High End: 3.1E+0 kg/site-day over 2 days/yr from 100 sites

or 6.2E+2 kg/yr

Water or Incineration

Conservative: 1.8E-1 kg/site-day over 14 days/yr from 100 sites

or 2.5E+2 kg/yr

RELEASE TOTAL

8.8E+2 kg/yr - all sites

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY

Tot. # of workers exposed via assessed routes: 0

Basis:

Inhalation:

negligible (liquid, VP < 0.001 torr, 

)

Dermal:

not required by SAT.

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INITIAL REVIEW ENGINEERING REPORT 

PMN: 05-0714

Use 1: 

Number of Sites/ Location: 400

unknown sites

Days/yr: 250

Basis:

Process Description: 

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY

IRER Note: The daily releases listed for any source below may

coincide with daily releases from the other sources to the same

medium. Air - negligible (VP < 0.01 torr).

Water

Output 2: 1.5E-1 kg/site-day over 250 days/yr from 400 sites

to:

Water or Incineration or Landfill

High End: 2.5E-2 kg/site-day over 60 days/yr from 400 sites

or 6.0E+2 kg/yr

Water or Incineration or Landfill

Conservative: 2.0E-3 kg/site-day over 250 days/yr from 400 sites

or 2.0E+2 kg/yr

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RELEASE TOTAL

1.6E+4 kg/yr - all sites

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY

Tot. # of workers exposed via assessed routes: 1,200

Basis:

Inhalation:

Exposure to Particulate (Class I)

Upper Bound: 6.0E-1 mg/day over 250 days/yr

Number of workers (all sites) with inhalation exposure: 1,200

Basis:

EB assesses 3 worker/site (default).

NOTE: The respirator class is: I. Particulate (including solid

or liquid droplets).

INHALATION MONITORING DATA REVIEW

1) Uncertainty (estimate based on model, regulatory limit,

 or data not specific to industry): Yes

2)a) Exposure level > 1 mg/day? No

 OR

 b) Hazard Rating for health of 2 or greater? 1-2 No

Inhalation Monitoring Data Desired? No

Dermal:

not required by SAT.

INITIAL REVIEW ENGINEERING REPORT 

PMN: 05-0714

Use 2: 

Number of Sites/ Location: 106

unknown sites

Days/yr: 250

Basis: 

Process Description: 

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY

IRER Note: The daily releases listed for any source below may

coincide with daily releases from the other sources to the same

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medium. Air - negligible (VP < 0.01 torr).

Water or Incineration or Landfill

High End: 2.5E-2 kg/site-day over 28 days/yr from 106 sites

or 7.4E+1 kg/yr

Water or Incineration or Landfill

Conservative: 1.9E-3 kg/site-day over 250 days/yr from 106 sites

or 5.0E+1 kg/yr

RELEASE TOTAL

1.2E+2 kg/yr - all sites

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY

Tot. # of workers exposed via assessed routes: 0

Basis:

Inhalation:

negligible (liquid, VP < 0.001 torr, 

)

Dermal:

not required by SAT.

INITIAL REVIEW ENGINEERING REPORT 

PMN: 05-0714

Use 3: 

Number of Sites/ Location: 1

unknown site

Days/yr: 118

Basis:

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Process Description: 

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY

IRER Note: The daily releases listed for any source below may

coincide with daily releases from the other sources to the same

medium.

Water

Output 2: 1.5E+0 kg/site-day over 118 days/yr from 1 site

Air

Output 2: 6.4E-1 kg/site-day over 118 days/yr from 1 site

Landfill

Output 2: 1.4E+1 kg/site-day over 118 days/yr from 1 site

or 1.6E+3 kg/yr

RELEASE TOTAL

1.9E+3 kg/yr - all sites

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY

Tot. # of workers exposed via assessed routes: 17

Basis: 

Inhalation:

Exposure to Mist (non-volatile) (Class I)

What-If: 3.7E-1 mg/day over 118 days/yr

Number of workers (all sites) with inhalation exposure: 17

Basis:

NOTE: The respirator class is: I. Particulate (including solid

or liquid droplets).

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INHALATION MONITORING DATA REVIEW

1) Uncertainty (estimate based on model, regulatory limit,

 or data not specific to industry): Yes

2)a) Exposure level > 1 mg/day? No

 OR

 b) Hazard Rating for health of 2 or greater? 1-2 No

Inhalation Monitoring Data Desired? No

Dermal:

not required by SAT.

MEMORANDUM of CBI TELEPHONE CONVERSATION

CALL BY: Aaron Osborne

Organization: ERG for EPA/OPPT/CEB

CALL TO: 

Organization: 

Date: 08/22/2005

Time: 8:30

Phone: 

PMN: 05-0714

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A-003 

Initial Review Exposure Report 

 for PMN P-05-714 

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Chemical ID: P-05-0714 Reviewer: Delpire/BC 

Partially updated exposure report for selected release scenarios (only) using updated SIC 

code stream flows and 2 Concentrations of Concern (5.6 ppb and 10 ppb). 

Chemical ID: P-05-0714 Assessor: Delpire/BC 

ENVIRONMENTAL RELEASES 

 Scenario#:1 Number of Release Sites: 

 Release Activity: 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: N/A N/A N/A 

(kg/yr) (kg/yr) (kg/yr) (kg/yr) 

Non-sludge/Sludge 

Release Days/yr: 0.00/0.00 N/A N/A 

Per Site Release: N/A/0.00 N/A N/A 

(kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

 

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12/28/2011 POSTFOCUS EXPOSURE REPORT Page 2 of 9 

 

 Chemical ID: P-05-0714 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 1 Number of Sites RELEASE ACTIVITY

SIC-CODE DESCRIPTION: 

SIC-CODE (S): EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 0.00 0.00 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 0.42 1.49 2.42 2.93 

ALL 10 2.54 7.19 12.35 14.75 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot 5.33E-07 3.26E-06 mg/kg/day 0.00 0.00 mg/kg/day 

LADCpot 2.73E-05 1.67E-04 mg/L 0.00 0.00 mg/kg 

Acute 

ADRpot 1.25E-04 6.01E-04 mg/kg/day 0.00 0.00 mg/kg/day 

SIC Code Comments: 

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 Chemical ID: P-05-0714 

SIC CODE EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 1 RELEASE ACTIVITY: 

SIC CODE DESCRIPTION: 

ASSOCIATED SIC CODES: 

SIC CODE RESULTS 

COC (μg/L) 

Percent of 

Year COC 

Exceeded 

Number of 

Days COC 

Exceeded 

Release 

days/year 

Loading 

(kg/site/day) 

Waste Water 

Treatment (%) 

High/Avg 

Analysis 

5.60 1 4 60.00 50.00 High 

10.00 0 2 60.00 50.00 High 

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Chemical ID: P-05-0714 Assessor: 

ENVIRONMENTAL RELEASES 

 Scenario#:2 Number of Release Sites 

 Release Activity: 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: N/A N/A N/A 

(kg/yr) (kg/yr) (kg/yr) (kg/yr) 

Non-sludge/Sludge 

Release Days/yr: 250.00 0.00/0.00 N/A N/A 

Per Site Release: N/A/0.00 N/A N/A 

(kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 

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12/28/2011 POSTFOCUS EXPOSURE REPORT Page 5 of 9 

 

 Chemical ID: P-05-0714 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 2 Number of Sites: RELEASE ACTIVITY:USE 1b 

SIC-CODE DESCRIPTION: 

SIC-CODE (S): EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

250. 0.00 0.00 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 0.35 1.24 2.02 2.44 

ALL 10 2.12 6.00 10.29 12.30 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot 1.85E-06 1.13E-05 mg/kg/day 0.00 0.00 mg/kg/day 

LADCpot 9.49E-05 5.80E-04 mg/L 0.00 0.00 mg/kg 

Acute 

ADRpot 1.04E-04 5.01E-04 mg/kg/day 0.00 0.00 mg/kg/day 

SIC Code Comments: 

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 Chemical ID: P-05-0714 

SIC CODE EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 2 RELEASE ACTIVITY: USE 1b 

SIC CODE DESCRIPTION: 

ASSOCIATED SIC CODES

SIC CODE RESULTS 

COC (μg/L) 

Percent of 

Year COC 

Exceeded 

Number of 

Days COC 

Exceeded 

Release 

days/year 

Loading 

(kg/site/day) 

Waste Water 

Treatment (%) 

High/Avg 

Analysis 

5.60 4 13 250.00 High 

10.00 2 6 250.00 High 

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Chemical ID: P-05-0714 Assessor: 

ENVIRONMENTAL RELEASES 

 Scenario#:3 Number of Release Sites: 

 Release Activity: 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: N/A N/A N/A 

(kg/yr) (kg/yr) (kg/yr) (kg/yr) 

Non-sludge/Sludge 

Release Days/yr: 0.00/0.00 N/A N/A 

Per Site Release: N/A/0.00 N/A N/A 

(kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 

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12/28/2011 POSTFOCUS EXPOSURE REPORT Page 8 of 9 

 

 Chemical ID: P-05-0714 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 3 Number of Sites: RELEASE ACTIVITY

SIC-CODE DESCRIPTION: 

SIC-CODE (S): EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

118. 0 0.00 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 2.67 5.74 9.07 11.03 

ALL 10 53.84 86.21 150.00 178.57 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot 6.73E-06 1.36E-04 mg/kg/day 0.00 0.00 mg/kg/day 

LADCpot 3.45E-04 6.96E-03 mg/L 0.00 0.00 mg/kg 

Acute 

ADRpot 4.80E-04 7.20E-03 mg/kg/day 0.00 0.00 mg/kg/day 

SIC Code Comments: 

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 Chemical ID: P-05-0714 

SIC CODE EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 3 RELEASE ACTIVITY: 

SIC CODE DESCRIPTION: 

ASSOCIATED SIC CODES: 

SIC CODE RESULTS 

COC (μg/L) 

Percent of 

Year COC 

Exceeded 

Number of 

Days COC 

Exceeded 

Release 

days/year 

Loading 

(kg/site/day) 

Waste Water 

Treatment (%) 

High/Avg 

Analysis 

5.60 32 118 118.00 High 

10.00 32 118 118.00 High 

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