### Appendix B. Table of Generic Data Requirements and Studies Used to Make the

**Reregistration Decision for Dazomet**  **(PC 035602**  **)** GUIDE TO APPENDIX B Appendix B contains a listing of data requirements which support the reregistration for active ingredients within the dazomet case covered b y this RED. It contains generic data requirements that appl y to dazomet in all products, including data requirements for which a “ty pical formulation” is the test substance. The data table is organize d in the following formats: 1. Data requirement (Column 1). The data requirements are listed in the order in which they

appear in 40 CFR 158. The reference numbers accompanying each test refer to the test protocols set in the Pesticide Assessment Guidance, which is available from the National Technical Information Service, 5285 Port Royal Road, Springfield, VA 22161. (703) 487 - 4650. 2. Use Pattern (Column 2). This column indicates the use patterns for which the data requirements apply. The following letter designations are used for the given use patterns. A. Terrestrial food B. Terrestrial feed C. Terrestrial non- food D. Aquatic food E. Aquatic non- food outdoor F. Aquatic non- food industrial G. Aquatic non- food residential H. Greenhouse food I. Greenhouse non- food J. Forestry K. Residential L. Indoor food M. Indoor non- food N. Indoor medical O. Indoor residential X . Materials preservatives Y. Industrial processes and water s ystems - once through Z. Industrial processes and water systems -not once through BB. Wood preservatives FF. Hi gh Exposure Antimicrobial GG. Low Exposure Antimicrobial 3. Bibliographic Citation (Column 3). If the Agency has acceptable data in its files, this column lists the identifying number of each study . This normally is the Master Record Identification (MRID) number, but may be a “GS” number is no MRID number has been assigned. Refer to the Bibliography appendix for a complete citation of the study .**Data Requirement Use Patterns**  **Citations New Guideline Number**  **Old Guideline**  **Number Description**  **PRODUC T CHEMISTRY**  830.7050 None UV/Visible Absorption ALL DATA GAP 830.7550 63 - 11 Partition coefficient, shake flask method ALL 43540903 **ECOLOGICAL EFFECTS** 850.1010 72 - 2 Acute Toxicity to Freshwater Invertebrates ALL 41819302 850.1025 72 - 3B Estuarine/Marine Toxicity

– Mollusk ALL DATA GAP 850.1035 72 - 3C Estuarine/Marine Toxicity

– Shrimp ALL DATA GAP 850.1075 72 - 1A Fish Acute Toxicity Bluegill ALL DATA GAP 850.1075 72 - 1B Fish Acute Toxicity

– Rainbow Trout ALL 45919420 850.1075 72 - 3A Estuarine/Marine Toxicity

– Fish ALL DATA GAP 850.1300 72 - 4(b) Aquatic Invertebrate Lifecycle (Freshwater) ALL 45634001 850.2100 71 - 1A Avian Acute Oral Toxicity

– Bobwhite quail ALL 42365101 850.2200 71 - 2a,b Avian Dietary ALL 42365102 850.2300 Avian Reproduction ALL DAT A GAP 850.3020 141 - 1 Honey bee acute contact LD50 ALL DATA GAP 850.4225 122 - 1(a) Seedling Emergence, Tier II ALL DATA GAP 850.4250 122 - 1(b) Vegetative Vigor, Tier II ALL DATA GAP 850.5400 122 - 2B Aquatic Plant Growth, Tier II ALL 45919422, 44588903, 45919421 , DATA GAP Special Study NA Avian Acute Inhalation C DATA GAP **TOXICOLOGY** 870.1100 81 - 1 Acute Oral Toxicity - Rat ALL 00132468, 00162331 870.1200 81 - 2 Acute Dermal Toxicity

– Rat ALL 00162330 42443501 , 42328802 870.1300 81 - 3 Acute Inhalation T oxicity

– Rat ALL 45919410, 41563003 870.2400 81 - 4 Primary Eye Irritation - Rabbit ALL 44400401, 00162328 , 41563002 870.2500 81 - 5 Primary Skin Irritation

– Rabbit ALL 00162329 , 42328801 870.2600 81 - 6 Dermal Sensitization ALL 43514802 , 47014505, 44031 801 870.3100 Subchronic Feeding

– Rat/Mouse ALL 41865502 870.3465 82 - 5 90 - Day Inhalation Toxicity

– Rat/Mouse ALL 45314802, 00162041 870.3700 83 - 3A Developmental Toxicity

– Rat ALL 41577101, 42170101 , DATA GAP 870.3800 83 - 4 Reproduction and Developmental Effects ALL DATA GAP 870.4100 83 - 1B Chronic Feeding Toxicity Study - Dog ALL 43275801 870.4200 83 - 2 Carcinogenicity

– Mouse/Rat ALL DATA GAP 870.5100 84 - 2 Bacterial Reverse Mutation Test ALL 00131910, 41482301,**Data Requirement Use Patterns**  **Citations New Guideline Number**  **Old Guideline**  **Number Description** 

(Ames Assay) 41497903 870.5375 84 - 2 Chromosomal Aberration in Chinese Hamster Ovary ALL 41497901 870.5395 84 - 2 Unscheduled DNA Synthesis

– Rat ALL 41482303 , DATA GAP 870.5700 84 - 2 In vitro mammalian gene mutation test ALL 41497902, 41482302 870.6200a 81 - 8 Acute neurotoxicity screen study in rats, Inhalation Acute Neurotoxicity ALL 43465302 870.7800 85 - 7 Immunotoxicity ALL DATA GAP **ENVIRONMENTAL FATE** 835.8100 163 - 3 Field Volatility ALL 46340401 , DATA GAP 835.2120 161 - 1 Hydrolysis ALL 45908301, 41479003, 42111401, 00158162 835.2240 161 - 2 Photodegradation - Water ALL 41479901, 42111402 835.2410 161 - 3 Photodegradation - Soil ALL 42569201 835.4100 162 - 1 Aerobic Soil Metabolism ALL 40211901, 42111403 835.4400 162 - 3 Anaerobic Aquatic Metabolism ALL 43596501, 43908426 835.6100 164 - 1 Terrestrial Field Dissipation ALL 41874801, 41874802 **OCCUPATIONAL AND RESIDENTIAL EXPOSURE** 875.1200 233 Dermal Exposure

– Indoor F, X, Y, Z, BB, FF, GG DATA GAP 875.1 4 00 234 Inhalation Exposure

– Indoor F, X, Y, Z, BB, FF, GG DATA GAP 875.1600 235 Appl ication exposure monitoring data reporting F, X, Y, Z, BB, FF, GG DATA GAP 875.1700 236 Product Use Information F, X, Y, Z, BB, FF, GG DATA GAP 875.2500 133 - 4 Inhalation Exposure

– Outdoor (Post-Application) F, X, Y, Z, BB, FF, GG DATA GAP 875.2700 235 Product Use Information F, X, Y, Z, BB, FF, GG DATA GAP 875.2800 133 - 1 Description of Human Activity F, X, Y, Z, BB, FF, GG DATA GAP 875.2900 134 Data Reporting and Calculations F, X, Y, Z, BB, FF, GG DATA GAP Special NA Fumigant Buffer Zone Posting Si gns C , I DATA GAP Special NA Training for Applicators Supervising Fumigations C , I DATA GAP Special NA Training Material for Handlers C , I DATA GAP