Appendix B. Table of Generic Data Requirements and Studies Used to Make the 

Reregistration Decision for Dazomet (PC 035602)

GUIDE TO APPENDIX B

Appendix B contains a listing of data requirements which support the 

reregistration for active ingredients within the dazomet case covered by this RED. It 

contains generic data requirements that apply to dazomet in all products, including data 

requirements for which a “typical formulation” is the test substance.

The data table is organized in the following formats:

1. Data requirement (Column 1). The data requirements are listed in the order in 

which they appear in 40 CFR 158. The reference numbers accompanying each 

test refer to the test protocols set in the Pesticide Assessment Guidance, which is 

available from the National Technical Information Service, 5285 Port Royal 

Road, Springfield, VA 22161. (703) 487-4650.

2. Use Pattern (Column 2). This column indicates the use patterns for which the 

data requirements apply. The following letter designations are used for the given 

use patterns.

A. Terrestrial food

B. Terrestrial feed

C. Terrestrial non-food

D. Aquatic food

E. Aquatic non-food outdoor

F. Aquatic non-food industrial

G. Aquatic non-food residential

H. Greenhouse food

I. Greenhouse non-food

J. Forestry

K. Residential

L. Indoor food

M. Indoor non-food

N. Indoor medical

O. Indoor residential

X . Materials preservatives

Y. Industrial processes and 

water systems-once through

Z. Industrial processes and water 

systems-not once through

BB. Wood preservatives

FF. High Exposure Antimicrobial

GG. Low Exposure Antimicrobial

3. Bibliographic Citation (Column 3). If the Agency has acceptable data in its files, this 

column lists the identifying number of each study. This normally is the Master Record 

Identification (MRID) number, but may be a “GS” number is no MRID number has been 

assigned. Refer to the Bibliography appendix for a complete citation of the study.
Data Requirement

Use Patterns Citations New Guideline Number

Old 

Guideline 

Number

Description

PRODUCT CHEMISTRY

830.7050 None UV/Visible Absorption ALL DATA GAP

830.7550 63-11 Partition coefficient, shake flask 

method

ALL 43540903

ECOLOGICAL EFFECTS

850.1010 72-2 

Acute Toxicity to Freshwater 

Invertebrates ALL 41819302

850.1025 72-3B Estuarine/Marine Toxicity –

Mollusk

ALL DATA GAP

850.1035 72-3C Estuarine/Marine Toxicity –

Shrimp

ALL DATA GAP

850.1075 72-1A Fish Acute Toxicity Bluegill ALL DATA GAP

850.1075 72-1B Fish Acute Toxicity – Rainbow 

Trout

ALL 45919420

850.1075 72-3A Estuarine/Marine Toxicity – Fish ALL DATA GAP

850.1300 72-4(b) Aquatic Invertebrate Lifecycle 

(Freshwater)

ALL 45634001

850.2100 71-1A Avian Acute Oral Toxicity –

Bobwhite quail

ALL 42365101

850.2200 71-2a,b Avian Dietary ALL 42365102

850.2300 Avian Reproduction ALL DATA GAP

850.3020 141-1Honey bee acute contact LD50 ALL DATA GAP

850.4225 122-1(a) Seedling Emergence, Tier II ALL DATA GAP

850.4250 122-1(b) Vegetative Vigor, Tier II ALL DATA GAP

850.5400 122-2B Aquatic Plant Growth, Tier II ALL 45919422, 44588903, 

45919421, DATA GAP

Special Study NA Avian Acute Inhalation C DATA GAP

TOXICOLOGY

870.1100 81-1 Acute Oral Toxicity - Rat ALL 00132468, 00162331

870.1200 81-2 Acute Dermal Toxicity – Rat ALL 00162330

42443501, 42328802

870.1300 81-3 Acute Inhalation Toxicity – Rat ALL 45919410, 41563003

870.2400 81-4 Primary Eye Irritation - Rabbit ALL 44400401, 00162328, 

41563002

870.2500 81-5 Primary Skin Irritation – Rabbit ALL 00162329, 42328801

870.2600 81-6 Dermal Sensitization ALL 43514802, 47014505,

44031801

870.3100 Subchronic Feeding – Rat/Mouse ALL 41865502

870.3465 82-5

90- Day Inhalation Toxicity –

Rat/Mouse

ALL 45314802, 00162041

870.3700 83-3A Developmental Toxicity – Rat ALL 41577101, 42170101, 

DATA GAP

870.3800 83-4

Reproduction and Developmental 

Effects

ALL DATA GAP

870.4100 83-1B Chronic Feeding Toxicity Study -

Dog

ALL 43275801

870.4200 83-2 Carcinogenicity – Mouse/Rat ALL DATA GAP

870.5100 84-2 Bacterial Reverse Mutation Test ALL 00131910, 41482301,
Data Requirement

Use Patterns Citations New Guideline Number

Old 

Guideline 

Number

Description

(Ames Assay) 41497903

870.5375 84-2

Chromosomal Aberration in 

Chinese Hamster Ovary

ALL 41497901

870.5395 84-2 Unscheduled DNA Synthesis – Rat ALL 41482303, DATA GAP

870.5700 84-2

In vitro mammalian gene mutation 

test

ALL 41497902, 41482302

870.6200a 81-8 

Acute neurotoxicity screen study in 

rats, Inhalation Acute 

Neurotoxicity

ALL

43465302

870.7800 85-7 Immunotoxicity ALL DATA GAP

ENVIRONMENTAL FATE

835.8100 163-3 Field Volatility ALL 46340401, DATA GAP

835.2120 161-1 Hydrolysis

ALL 45908301,

41479003,

42111401, 00158162

835.2240 161-2 Photodegradation - Water ALL 41479901,

42111402

835.2410 161-3 Photodegradation - Soil ALL 42569201

835.4100 162-1 Aerobic Soil Metabolism ALL 40211901, 

42111403

835.4400 162-3 Anaerobic Aquatic Metabolism ALL 43596501, 43908426

835.6100 164-1 Terrestrial Field Dissipation ALL 41874801,

41874802

OCCUPATIONAL AND RESIDENTIAL EXPOSURE

875.1200 233 Dermal Exposure – Indoor F, X, Y, Z, BB, 

FF, GG DATA GAP

875.1400 234 Inhalation Exposure – Indoor F, X, Y, Z, BB, 

FF, GG DATA GAP

875.1600 235 Application exposure monitoring 

data reporting

F, X, Y, Z, BB, 

FF, GG DATA GAP

875.1700 236 Product Use Information F, X, Y, Z, BB, 

FF, GG DATA GAP

875.2500 133-4

Inhalation Exposure – Outdoor 

(Post-Application)

F, X, Y, Z, BB, 

FF, GG DATA GAP

875.2700 235 Product Use Information F, X, Y, Z, BB, 

FF, GG DATA GAP

875.2800 133-1 Description of Human Activity F, X, Y, Z, BB, 

FF, GG DATA GAP

875.2900 134 Data Reporting and Calculations F, X, Y, Z, BB, 

FF, GG DATA GAP

Special NA Fumigant Buffer Zone Posting 

Signs

C, I DATA GAP

Special NA Training for Applicators 

Supervising Fumigations C, I DATA GAP

Special NA Training Material for Handlers C, I DATA GAP