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                            Funding & Awards
 Designer Amphetamines in Forensic Toxicology: Analysis and Prevalence
Note:
              This awardee has received supplemental funding. This award detail page includes information about both the original award and supplemental awards.
Award Information
Awardee
              Sam Houston State University
Award #
              2008-DN-BX-K126
Funding Category
              Competitive
Location
                    Huntsville, TX
Awardee County
              Walker
Congressional District
              8
Status
              Closed
Funding First Awarded
              2008
Total funding (to date)
              $466,492
Original Solicitation
              NIJ FY 08 Research and Development in Forensic Toxicology: Invited Full Proposals
Description of original award (Fiscal Year 2008, $226,550)
This project seeks to develop screening and confirmatory methods for new, emerging  'designer' amphetamines, using the most widely used technologies in forensic toxicological laboratories today, specifically enzyme-linked immunosorbent assay (ELISA) and gas chromatography/mass spectrometry (GC/MS).  The cross-reactivity of antibodies used in commercial immunoassays for methamphetamine will be examined to determine whether existing commercial immunoassays are effective screening tools for emerging designer drugs.  Extraction protocols and chemical derivatives will be considered in order to develop a confirmatory analysis using GC/MS, taking into consideration existing resources that do not place an undue burden on the laboratory or require extensive familiarization.  The resulting procedures will be scientifically validated according to established procedures and accreditation requirements.  Such validated procedures, using commonly used technologies and methodologies, will assist in reducing case backlog in the area of forensic toxicology.  Finally, prevalence of these drugs in actual forensic toxicology casework samples will be investigated.
ca/ncf
Supplemental Award 1 (Fiscal Year 2009, $239,942)
This award will provide funding to Sam Houston State University to expand research of emerging designer amphetamines in casework, by increasing the number of targeted drugs from 10 to as many as 27, and by examining the prevalence of the targeted compounds in more case samples, from 500 cases to 2500 cases, drawn from a wider geographic area.  The extension of this research will provide routine testing laboratories with practical information that will allow them to implement new analytical procedures for the detection of the newer designer amphetamines.  This will reduce case backlog by allowing for testing for more compounds with one test.
ca/ncf


  
Grant-Funded Publications
        
                      Designer Psychostimulants in Urine by Liquid Chromatography-Tandem Mass Spectrometry
                  Designer Psychostimulants in Urine by Liquid Chromatography–Tandem Mass Spectrometry
                  Designer Amphetamines in Forensic Toxicology Casework
                  Evaluation of Commercial Enzyme Linked Immunosorbent Assays to Identify Psychedelic Phenethylamines
                  Simultaneous Detection of Ten Psychedelic Phenethylamines in Urine by Gas Chromatography-Mass Spectrometry

  
Date Created: September 15, 2008
    
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