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                            Funding & Awards
 High Throughput Mass Spectrometry to Exploit Genetic Differences in Same-Length STR Alleles
Award Information
Awardee
              Ibis Biosciences, Inc., a Subsidiary of Isis Pharmaceuticals
Award #
              2008-DN-BX-K304
Funding Category
              Competitive
Location
                    Carlsbad, CA
Congressional District
              49
Status
              Closed
Funding First Awarded
              2008
Total funding (to date)
              $649,821
Original Solicitation
              NIJ FY 08 Forensic DNA Research and Development: Invited Full Proposals
Description of original award (Fiscal Year 2008, $649,821)
The goal of this project is to build upon work performed under 2006-DN-BX-K011, which  successfully demonstrated the use of mass spectrometry  to analyze Short Tandem Repeat (STR) forensic DNA markers. The current project will expand the approach to the analysis of Y-chromosome STRs; compile information on the frequency of single nucleotide polymorphisms (SNPs) found within the STRs; and analyze samples linked by extended family relationships to verify the faithful transmission of SNP alleles among generations. Further development and validation of this mass spectrometry platform will result in a DNA crime laboratory tool that provides increased discriminatory power while offering the throughput advantages of a  fully automated platform.
ca/ncf



  
Grant-Funded Publications
        
                      Automated Analysis of Sequence Polymorphism in STR Alleles by PCR and Direct Electrospray Ionization Mass Spectrometry
                  High Throughput Mass Spectrometry to Exploit Genetic Differences in Same-Length STR Alleles

  
Date Created: September 10, 2008
    
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