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                            Funding & Awards
 Identification of Forensically Relevant Fluids and Tissues by Small RNA Profiling
Award Information
Awardee
              University of Central Florida
Award #
              2009-DN-BX-K255
Funding Category
              Competitive
Location
                    Orlando, FL
Awardee County
              Orange
Congressional District
              7
Status
              Closed
Funding First Awarded
              2009
Total funding (to date)
              $328,962
Original Solicitation
              NIJ FY 09 Forensic DNA Research and Development: Invited Full Proposals
Description of original award (Fiscal Year 2009, $328,962)
Recently, there has been an explosion of interest in a novel class of small non-coding RNAs, microRNAs (~20-25 bases in length), with numerous published studies reporting that some miRNAs are expressed in a tissue specific manner. Additionally, another novel class of small regulatory RNAs, piwi-interacting RNAs (~26-30 bases in length), have been identified only in sperm-producing cells in mammals. It is therefore possible that this class of small RNAs could be ideally suited for the identification of semen. This research seeks to provide a novel strategy for the identification of the body fluid origin of dried forensic biological material (blood, semen, saliva, vaginal secretions, menstrual blood, skin) through expression profiling of body fluid specific small RNAs (miRNAs and piRNAs).
ca/ncf



  
Grant-Funded Publications
        
                      Identification of Forensically Relevant Fluids and Tissues by Small RNA Profiling
                  Binary logistic regression models enable miRNA profiling to provide accurate identification of forensically relevant body fluids and tissues
                  RNA Profiling for the Identification of the Tissue Origin of Dried Stains in Forensic Biology
                  Identification of Forensically Relevant Body Fluids Using a Panel of Differentially Expressed microRNAs

  
Date Created: September 22, 2009
    
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