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                            Funding & Awards
 The Use of MiniSTRs as Tools for the Investigation of DNA Degradation and Inhibition
Award Information
Awardee
              The Florida International University Board of Trustees
Award #
              2005-MU-BX-K073
Funding Category
              Competitive
Location
                    Miami, FL
Awardee County
              Dade
Congressional District
              24
Status
              Closed
Funding First Awarded
              2005
Total funding (to date)
              $171,394
Original Solicitation
              Forensic DNA Research & Development Full Application
Description of original award (Fiscal Year 2005, $171,394)
This project will build on the work previously performed under award 2002-IJ-CX-K007, which demonstrated the utility of miniSTRs for analysis of degraded or compromised DNA evidence. The principal investigator (in conjunction with Dr. John Butler from NIST) has shown these miniSTR sets to be highly robust and capable of results that are compatible with commercial kits. While the validation process of these markers has begun, further tests are needed to examine their application to non-routine forensic samples such as bone, hair, fingernail scrapings, and low copy number DNA.  A wider ranging population study is also needed to examine the application of MiniSTRs in the analysis of Asian and other population groups not analyzed in the previous population studies. 



ca/ncf



  
Grant-Funded Publications
        
                      A Study of PCR Inhibition Mechanisms Using Real Time PCR
                  Developmental Validation of Reduced-Size STR Miniplex Primer Sets
                  The Application of Miniplex Primer Sets in the Analysis of Degraded DNA from Human Skeletal Remains

  
Date Created: September 18, 2005
    
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