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                            Funding & Awards
 NIJ Proposal to Enhance Methods for Studying Degraded DNA
Award Information
Awardee
              Washington State University Pullman
Award #
              2008-DN-BX-K008
Funding Category
              Competitive
Location
                    Pullman, WA
Congressional District
              5
Status
              Closed
Funding First Awarded
              2008
Total funding (to date)
              $595,196
Original Solicitation
              NIJ FY 08 Forensic DNA Research and Development: Invited Full Proposals
Description of original award (Fiscal Year 2008, $595,196)
This project addresses the major issue of DNA testing of compromised samples and will provide further insight about the behavior of degraded DNA. The activities to be performed include the determination of which treatment of bone can entirely remove surface contamination; the testing of different thermo-stable polymerases with respect to their ability to amplify DNA that has been co-extracted with PCR inhibitors; and an examination of the extent and nature of post mortem genetic damage found in compromised human remains.  The results of the experiments will play a role in improving the success rate of forensic DNA testing of older criminal cases, cold cases, missing persons cases, mass fatality events, and war dead. ca/ncf



  
Grant-Funded Publications
        
                      Evaluating the Efficacy of Various Thermo-Stable Polymerases Against Co-Extracted PCR Inhibitors in Ancient DNA Samples
                  Evaluation of Methods that Subdue the Effects of Polymerase Chain Reaction Inhibitors in the Study of Ancient and Degraded DNA
                  Further Evaluation of the Efficacy of Contamination Removal From Bone Surfaces
                  Mitochondrial DNA Preservation Across 3000 Year Old Northern Fur Seal Ribs is Not Related to Bone Density: Implications for Forensic Investigations
                  One of the Key Characteristics of Ancient DNA Low Copy Number May be a Product of its Extraction
                  NIJ Proposal to Enhance Methods for Studying Degraded DNA, Final Technical Report
                  To clone or not to clone: Method analysis for retrieving consensus sequences in ancient DNA samples

  
Date Created: September 15, 2008
    
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                      Optimizing Analytical Parameters for Detection of Chronic and Single Dose Drug Exposure in Forensic Hair Analysis
                  Evaluation of Target Enrichment for SNP Genotyping of Skeletal Remains
                  Understanding the Implementation and Impact of Credible Messenger Mentoring on Youth Across Settings
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