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                            Funding & Awards
 Microfabricated Capillary Array Electrophoresis Genetic Analyzers for Forensic Short Tanden Repeat DNA Profiling
Award Information
Awardee
              Regents of The University of California
Award #
              2004-DN-BX-K216
Funding Category
              Competitive
Location
                    Berkeley, CA
Congressional District
              13
Status
              Closed
Funding First Awarded
              2004
Total funding (to date)
              $821,623
Original Solicitation
              Forensic DNA Research & Development
Description of original award (Fiscal Year 2004, $821,623)
This project will develop microfabricated capillary array electrophoresis (μCAE) instruments and methods that integrate sample amplification, product clean-up and multiplex STR electrophoretic analysis of up to 96 samples on a single-wafer system. The development and initial evaluation will be performed at the Department of Chemistry at UC Berkeley in collaboration with the Virginia Division of Forensic Science (VADFS) and the Palm Beach Sheriff Office (PBSO). Once developed, μCAE instruments will be placed at VADFS for evaluation by VADFS and PBSO personnel. These systems together with advanced reagent and fluorescent labeling methods will be valuable for forensic STR analysis because the fully integrated microfluidic process will improve analysis sensitivity and reliability, eliminate operator variability, reduce sample contamination and tracking issues, reduce analysis cost, and make modern STR analysis available to a wider range of forensic laboratories. 

ca/ncf



  
Grant-Funded Publications
        
                      Microfabricated Capillary Array Electrophoresis Genetic Analyzers for Forensic Short Tandem Repeat DNA Profiling
                  Real-Time Forensic DNA Analysis at a Crime Scene Using a Portable Microchip Analyzer
                  Forensic Laboratory Tests the Berkeley Microfabricated Capillary Array Electrophoresis Device
                  Rapid and High-Throughput Forensic Short Tandem Repeat Typing Using a 96-Lane Microfabricated Capillary Array Electrophoresis Microdevice
                  Integrated Portable PCR-capillary Electrophoresis Microsystem for Rapid Forensic Short Tandem Repeat Typing

  
Date Created: September 20, 2004
    
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