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                            Funding & Awards
 Meeting National Safety Council Recommendations: Accurate Rapid Tests and Laboratory Confirmation Procedures for Fentanyl and Prevalent Opioids in Oral Fluid
Award Information
Awardee
              9 DELTA ANALYTICAL, LLC
Award #
              15PNIJ-23-GG-04233-RESS
Funding Category
              Competitive Discretionary
Location
                    ONTARIO, CA
Awardee County
              San Bernardino
Congressional District
              35
Status
              Open
Funding First Awarded
              2023
Total funding (to date)
              $434,500
Original Solicitation
              NIJ FY23 Research and Development in Forensic Science for Criminal Justice Purposes
Description of original award (Fiscal Year 2023, $434,500)
Meeting National Safety Council Recommendations: Accurate Rapid Tests and Laboratory Confirmation Procedures for Fentanyl and Prevalent Opioids in Oral Fluid
Description of the problem: Fentanyl and synthetic opioid use, abuse, overdose, and deaths are currently occurring at an alarming rate in the USA. The law enforcement community, the Food and Drug Administration (FDA) and the Centers for Disease Control (CDC) are all keenly aware of the urgency in addressing an unmet public health need to identify opioid overdose in individuals as rapidly as possible.  Individual health outcomes will be significantly improved by allowing the correct treatments to be administered quickly.
Proposed solution:
a. development of an inexpensive, visually read testing device which allows the operator to rapidly identify the presence of fentanyl and/or other opioids in oral fluid taken from the subject, and
b. development of environmentally friendly confirmatory laboratory procedures for the remaining specimen.
The device is “Made in America”
	The same specimen used for rapid testing will be confirmed by newly developed environmentally friendly laboratory procedures
	Laboratory procedures will allow comparison of on-site results from clinical specimens to confirmatory methods which are necessary to perform characterization and performance of the device
	Laboratory procedures will be published and provided to both forensic and clinical facilities, to assist in their support of law enforcement
Drugs in oral fluid reflect related compounds circulating in blood, therefore oral fluid analysis is indicative of free drugs in the body. The new device for presumptive testing, followed by laboratory confirmation for evidential analysis will promote the use of oral fluid in many areas including: identification of drugged drivers, in suspected overdose antemortem situations, in prisons testing and among parolees.
Commercially available instrumented devices are expensive and require training of the officers to operate correctly. Currently no commercially available instrumented device includes fentanyl or oxycodone analysis, and none are “Made in America”.
Commercially available non-instrumented (visually read) devices are generally inexpensive and disposable, but none are manufactured in the USA. The current commercially available devices do not include fentanyl, which is the major issue in the opioid crisis.
The success of our project will provide a solution to a currently unmet public health need, assist law enforcement in assessing various overdose situations, and will be useful in opioid treatment clinics. CA/NCF

  
Date Created: September 26, 2023
    
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                      Development of a Stable Matrix-Matched Standard for Molecular and Elemental Analysis of Hair in Forensic Toxicology
                  Sampling and Selection Bias in Research using Documented Skeletal Collections
                  Beyond Suspect Identification: Fingerprint Aging with Machine Learning and Multidimensional Chemical Analysis
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