# Support Documents for
Significant New Use Rules (SNUR) on
Premanufacture Notice (PMN)

P-09-72

EPA Docket EPA-HQ-OPPT-2010-1075

# Index

A-001 Structure Activity Team (SAT) Report for
PMN P -09-72

A-002 Initial Review Engineering Report for
PMN P -09-72

A-003 Initial Review Exposure Report for
PMN P -09-72

# A-001
Structure Activity Team (SAT) Report

for PMN P-09-72

## SAT Report PMN Number: P-09-0072 SAT Date: 11/25/2008

Related cases : Health related cases: Ecotox related cases:

Concern levels :


### Type of Concern: Health Eco Comments Level of Concern: 1-2 3

Persistence Bioaccum Toxicity Comments 1 1 1

Exposure Based Review : Health: N o Ecotox: N o

Routes of exposure : Health: Inhalation, dermal, ingestion, drinking water Ecotox: All releases to water Fate: ;

Keywords : Keywords: IRR-E DEVEL UNCERT MUTA

Summary of Assessment :

Fate : Fate Summary: P-09-0072 FATE: Liquid with MP = -62.4 EC (M) log Kow = 1.81 (M); S = 83 mg/L at 25 EC (M) VP = 1.3E-2 torr at 25 EC ( N OMO5) BP = 269.1 EC (M) H < 1.00E-8 (E) log Koc = 2.32 (E) log Fish BCF = 0.69 (E) POTW removal (%) = 90 via biodegradation; OECD 301F(Mano Resp): 14.7%/28d. Time for complete ultimate aerobic biodeg = wk

### Sorption to soils/sediments = low PBT Potential: P1B1 *CEB FATE: Migration to ground water = moderate

Health : Health Summary: Absorption is good all routes, based on analogs. There are concerns for eye irritation and developmental toxicity, and uncertain concern for mutagenicity, based on phenols. Test Data: Submitted with the PMN: Salmonella assay negative with and without activation; N ot a dermal sensitizer in guinea pigs; Moderate eye irritant in rabbits; N ot a dermal irritant in rabbits; Rat acute oral (gavage) LD50 > 2000 mg/kg

Submitted with Salmonella assay negative with and without activation; N ot a dermal sensitizer in guinea pigs; N ot a photosensitizer in guinea pigs; Moderate eye irritant in rabbits; Mouse acute oral LD50 > 2800 mg/kg

Submitted with N ot a dermal sensitizer in guinea pigs; N ot a photosensitizer in guinea pigs; Moderate eye irritant in rabbits; Mouse acute oral LD50 > 1800 mg/kg

Ecotox :

Test Organism Test Type Test End Point Predicted Measured Comments

fish 96-h LC50 25 daphnid 48-h LC50 9 green algal 96-h EC50 41
fish

_ chronic value 1.9/0.006 30-day/60-day daphnid

_ chronic value 1.7 algal

_ chronic value 19 Sewage Sludge 3-h EC50

_ Sewage Sludge

_ Chronic Value

_ Ecotox Values Comments: Predictions are based on SARs for phenols; SAR chemical class

= p henol; MW 196; log Kow = 2.10 (EPI); p H7; effective concentrations based on 100% active ingredients and nominal concentrations; hardness <180.0 mg/L as CaCO3; and TOC <2.0 mg/L;

### Factors Values Comments Assessment Factor 10 Concentration of Concern ( p pb) 1

SARs SAR Class

Ecotox Factors Comments:

SAT Chair: J. Kwiat

# A-002
Initial Review Engineering Report

for PMN P-09-72

### INITIAL REVIEW ENGINEERING REPORT
P-09-0072 Focus Ready Draft 12/18/2008

ENGINEER: Macek \ JAS PV (kg/yr):

Revision Notes/Assessment Overview:

SUBMITTER: Mane, USA (submitter)

USE:

OTHER USES: N one found.

MSDS: Yes LABEL : N o

Gen Eqpt: rubber or synthetic gloves/ conventional eye/face protection Respirator: respirator not normally required, if prolonged exposure to high concentrations, use OSHA respirator Health Effects: avoid contact with skin and eyes/ slightly irritating to skin/ moderately irritating to eyes TLV/PEL : - none established.

CRSS: Chemical Name: Phenol, 2-ethoxy-4-(ethoxymethyl)- S-H2O: 0.083 g/L @ VP: 1.3E-2 torr @ MW: 196 0.0%<500 0.0%<1000 Physical State and Misc CRSS Info: Neat: Liquid Mfg: N K, imported Proc/Form: Solution End Use: Solid/liquid in finished products. Submitted data: vanilla, amber, sandalwood scent, mp = -62.4°C, bp = 269.1°C, vp <0.001 torr (calculated), ws = 83 mg/L, log P = 1.81, d = 1.072-1.082 g/cc, flash point = 100.7°C. The structure is consistent with IR, 1H- and 13C- N MR spectra provided. Estimated data: EPI (with mp entered as -62.4°C, bp as 269.1 °C, ws as 0.83 g/L, log P as 1.81): bp = 297.63°C, vp = 0.00372 torr, ws = 4.285 g/L, log P = 2.10. N OMO5 for bp = 269.1°C: vp = 0.013 torr. ACD Labs (Prop database): bp = 291.7°C, vp = 1.1E-3 torr, ws = 2.4 g/L, log P = 1.988.

Consumer Use: Yes

SAT (concerns):

Migration to groundwater: Moderate PBT rating: P 1 B 1 T 1 Health: 1-2, Dermal, Inhalation Eco: 3, Water (All releases to water with a CC = 100 ppb)

OCCUPATIONAL EXPOSURE RATING: 1-2C

NOTES & KEY ASSUMPTIONS: Generated by the 06/07/2005 version of ChemSTEER.POLLUTION PREVENTION CONSIDERATIONS : N one.

P2 REC:

EXPOSURE-BASED REVIEW:P-09-0072

Proc1:

Number of Sites/Location: 1 submitter site(s) MANE, USA Wayne NJ 07470 Basis: Process Description:



## ENVIRONMENTAL RELEASES ESTIMATE SUMMARY IRER Note: The daily releases listed for any source below may coincide with daily releases from the other sources to the same medium.

Water Conservative: 10.0E-2 kg/site-day over 20 day/yr from 1 sites or 2.0E+0 kg/y r to: POTW, per submission

Air Output 2: 9.0E-4 kg/site-day over 20 day/yr from 1 sites or 1.8E-2 kg/y r to: Air

Air Typical: 6.9E-7 kg/site-day over 20 day/yr from 1 sites or 1.4E-5 kg/y r Worst Case: 1.4E-6 kg/site-day over 20 day/yr from 1 sites or kg/y r to: Air

Air Typical: 6.9E-7 kg/site-day over 20 day/yr from 1 sites or 1.4E-5 kg/y r Worst Case: 1.4E-6 kg/site-day over 20 day/yr from 1 sites or kg/y r to: Air

Air Output 2: 8.4E-8 kg/site-day over 20 day/yr from 1 sites or 1.7E-6 kg/y r to: Air

Water or Incineration or LandfillHigh End: 1.1E-1 kg/site-day over 11 day/yr from 1 sites or 1.2E+0 kg/y r to: uncertain

Air Typical: 3.3E-6 kg /site-day over 20 day/yr from 1 sites or 6.6E-5 kg/y r Worst Case: 2.6E-5 kg/site-day over 20 day/yr from 1 sites or kg/y r to: from: Sampling Liquid Raw Material basis:



## RELEASE TOTAL 3.3E+0 kg/y r - all sites



## OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY Tot. # of workers exposed via assessed routes: 15 Basis:

Dermal:

Exposure to Liquid High End: 3.5E+2 mg/day over 20 days/y r Number of workers (all sites) with Dermal exposure: 5 Basis:

Inhalation:

Exposure to Vapor Typical: 3.3E-4 mg/day over 20 days/y r Worst Case: 2.0E-2 mg/day over 20 days/y r Number of workers (all sites) with Inhalation exposure: 5 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Dermal:Exposure to Liquid High End: 1.8E+3 mg/day over 20 days/y r Number of workers (all sites) with Dermal exposure: 10 Basis:

Inhalation:

Exposure to Vapor Typical: 3.3E-4 mg/day over 20 days/y r Worst Case: 2.0E-2 mg/day over 20 days/y r Number of workers (all sites) with Inhalation exposure: 10 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Dermal:

Exposure to Liquid High End: 8.8E+2 mg/day over 20 days/y r Number of workers (all sites) with Dermal exposure: 10 Basis:

Inhalation:

Exposure to Vapor Typical: 1.6E-3 mg/day over 20 days/y r Worst Case: 3.8E-1 mg/day over 20 days/y r Number of workers (all sites) with Inhalation exposure: 10 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N oP-09-0072

Proc2:

Number of Sites/Location: 1 submitter site(s) unknown customer site Basis: Process Description:



## ENVIRONMENTAL RELEASES ESTIMATE SUMMARY IRER Note: The daily releases listed for any source below may coincide with daily releases from the other sources to the same medium.

Air Typical: 1.4E-6 kg/site-day over 200 day/yr from 1 sites or 2.7E-4 kg/y r Worst Case: 2.7E-6 kg/site-day over 200 day/yr from 1 sites or kg/y r to: Air

Air Output 2: 4.6E-8 kg/site-day over 200 day/yr from 1 sites or 9.2E-6 kg/y r to: Air

Water or Incineration or Landfill High End: 3.1E-1 kg/site-day over 19 day/yr from 1 sites or 5.9E+0 kg/y r to: uncertain

Air Typical: 1.4E-7 kg/site-day over 200 day/yr from 1 sites or 2.7E-5 kg/y r Worst Case: 2.7E-7 kg/site-day over 200 day/yr from 1 sites or kg/y r to: Air

Water or Air or Landfill Output 2: 6.8E-3 kg/site-day over 200 day/yr from 1 sites or 1.4E+0 kg/y r to: water, landfill or airAir Typical: 6.6E-7 kg/site-day over 200 day/yr from 1 sites or 1.3E-4 kg/y r Worst Case: 5.3E-6 kg/site-day over 200 day/yr from 1 sites or kg/y r to: Air

Air Output 2: 6.6E-4 kg/site-day over 200 day/yr from 1 sites or 1.3E-1 kg/y r to: Air

Air Output 2: 1.4E-3 kg/site-day over 200 day/yr from 1 sites or 2.9E-1 kg/y r to: Air

Water or Incineration or Landfill Conservative: 2.0E-2 kg/site-day over 200 day/yr from 1 sites or 4.0E+0 kg/y r to: uncertain



## RELEASE TOTAL 1.2E+1 kg/y r - all sites



## OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY Tot. # of workers exposed via assessed routes: 29 Basis:

Dermal:

Exposure to Liquid High End: 8.8E+1 mg/day over 200 days/y r Number of workers (all sites) with Dermal exposure: 29 Basis:Inhalation:

Exposure to Vapor Typical: 6.6E-4 mg/day over 200 days/y r Worst Case: 3.9E-2 mg/day over 200 days/y r Number of workers (all sites) with Inhalation exposure: 29 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Inhalation:

Exposure to Vapor Typical: 6.6E-5 mg/day over 200 days/y r Worst Case: 3.9E-3 mg/day over 200 days/y r Number of workers (all sites) with Inhalation exposure: 29 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Dermal:

Exposure to Solid High End: 1.6E+2 mg/day over 200 days/y r Number of workers (all sites) with Dermal exposure: 29 Basis:

Inhalation:

Exposure to Particulate Upper Bound: 7.5E-1 mg/day over 200 days/y r Number of workers (all sites) with Inhalation exposure: 29 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Inhalation:Exposure to Vapor Typical: 3.2E-4 mg/day over 200 days/y r Worst Case: 7.6E-2 mg/day over 200 days/y r Number of workers (all sites) with Inhalation exposure: 29 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Dermal:

Exposure to Liquid High End: 8.8E+1 mg/day over 200 days/y r Number of workers (all sites) with Dermal exposure: 29 Basis:

Inhalation:

Exposure to Vapor Typical: 1.7E-2 mg/day over 200 days/y r Worst Case: 7.9E-2 mg/day over 200 days/y r Number of workers (all sites) with Inhalation exposure: 29 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

### INITIAL REVIEW ENGINEERING REPORT
P-09-0072 Focus Ready Draft 12/18/2008

ENGINEER: Macek \ JAS PV (kg/yr):

Revision Notes/Assessment Overview:

SUBMITTER: Mane, USA (submitter)

USE:

OTHER USES: N one found.

MSDS: Yes LABEL : N o

Gen Eqpt: rubber or synthetic gloves/ conventional eye/face protection Respirator: respirator not normally required, if prolonged exposure to high concentrations, use OSHA respirator Health Effects: avoid contact with skin and eyes/ slightly irritating to skin/ moderately irritating to eyes TLV/PEL : - none established.

CRSS: Chemical Name: Phenol, 2-ethoxy-4-(ethoxymethyl)- S-H2O: 0.083 g/L @ VP: 1.3E-2 torr @ MW: 196 0.0%<500 0.0%<1000 Physical State and Misc CRSS Info: Neat: Liquid Mfg: N K, imported Proc/Form: Solution End Use: Solid/liquid in finished products. Submitted data: vanilla, amber, sandalwood scent, mp = -62.4°C, bp = 269.1°C, vp <0.001 torr (calculated), ws = 83 mg/L, log P = 1.81, d = 1.072-1.082 g/cc, flash point = 100.7°C. The structure is consistent with IR, 1H- and 13C- N MR spectra provided. Estimated data: EPI (with mp entered as -62.4°C, bp as 269.1 °C, ws as 0.83 g/L, log P as 1.81): bp = 297.63°C, vp = 0.00372 torr, ws = 4.285 g/L, log P = 2.10. N OMO5 for bp = 269.1°C: vp = 0.013 torr. ACD Labs (Prop database): bp = 291.7°C, vp = 1.1E-3 torr, ws = 2.4 g/L, log P = 1.988.

Consumer Use: Yes

SAT (concerns):

Migration to groundwater: Moderate PBT rating: P 1 B 1 T 1 Health: 1-2, Dermal, Inhalation Eco: 3, Water (All releases to water with a CC = 100 ppb)

OCCUPATIONAL EXPOSURE RATING: 1-2C

NOTES & KEY ASSUMPTIONS: Generated by the 06/07/2005 version of ChemSTEER.POLLUTION PREVENTION CONSIDERATIONS : N one.

P2 REC:

EXPOSURE-BASED REVIEW:P-09-0072

Proc1:

Number of Sites/Location: 1 submitter site(s) MANE, USA Wayne NJ 07470 Basis: Process Description:



## ENVIRONMENTAL RELEASES ESTIMATE SUMMARY IRER Note: The daily releases listed for any source below may coincide with daily releases from the other sources to the same medium.

Water Conservative: 10.0E-2 kg/site-day over 20 day/yr from 1 sites or 2.0E+0 kg/y r to: POTW, per submission

Air Output 2: 9.0E-4 kg/site-day over 20 day/yr from 1 sites or 1.8E-2 kg/y r to: Air

Air Typical: 6.9E-7 kg/site-day over 20 day/yr from 1 sites or 1.4E-5 kg/y r Worst Case: 1.4E-6 kg/site-day over 20 day/yr from 1 sites or kg/y r to: Air

Air Typical: 6.9E-7 kg/site-day over 20 day/yr from 1 sites or 1.4E-5 kg/y r Worst Case: 1.4E-6 kg/site-day over 20 day/yr from 1 sites or kg/y r to: Air

Air Output 2: 8.4E-8 kg/site-day over 20 day/yr from 1 sites or 1.7E-6 kg/y r to: Air

Water or Incineration or LandfillHigh End: 1.1E-1 kg/site-day over 11 day/yr from 1 sites or 1.2E+0 kg/y r to: uncertain

Air Typical: 3.3E-6 kg/site-day over 20 day/yr from 1 sites or 6.6E-5 kg/y r Worst Case: 2.6E-5 kg/site-day over 20 day/yr from 1 sites or kg/y r to: from: basis:



## RELEASE TOTAL 3.3E+0 kg/y r - all sites



## OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY Tot. # of workers exposed via assessed routes: 15 Basis:

Dermal:

Exposure to Liquid High End: 3.5E+2 mg/day over 20 days/y r Number of workers (all sites) with Dermal exposure: 5 Basis:

Inhalation:

Exposure to Vapor Typical: 3.3E-4 mg/day over 20 days/y r Worst Case: 2.0E-2 mg/day over 20 days/y r Number of workers (all sites) with Inhalation exposure: 5 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Dermal:Exposure to Liquid High End: 1.8E+3 mg/day over 20 days/y r Number of workers (all sites) with Dermal exposure: 10 Basis:

Inhalation:

Exposure to Vapor Typical: 3.3E-4 mg/day over 20 days/y r Worst Case: 2.0E-2 mg/day over 20 days/y r Number of workers (all sites) with Inhalation exposure: 10 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Dermal:

Exposure to Liquid High End: 8.8E+2 mg/day over 20 days/y r Number of workers (all sites) with Dermal exposure: 10 Basis:

Inhalation:

Exposure to Vapor Typical: 1.6E-3 mg/day over 20 days/y r Worst Case: 3.8E-1 mg/day over 20 days/y r Number of workers (all sites) with Inhalation exposure: 10 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N oP-09-0072

Proc2:

Number of Sites/Location: 1 submitter site(s) unknown customer site Basis: Process Description:



## ENVIRONMENTAL RELEASES ESTIMATE SUMMARY IRER Note: The daily releases listed for any source below may coincide with daily releases from the other sources to the same medium.

Air Typical: 1.4E-6 kg/site-day over 200 day/yr from 1 sites or 2.7E-4 kg/y r Worst Case: 2.7E-6 kg/site-day over 200 day/yr from 1 sites or kg/y r to: Air

Air Output 2: 4.6E-8 kg/site-day over 200 day/yr from 1 sites or 9.2E-6 kg/y r to: Air

Water or Incineration or Landfill High End: 3.1E-1 kg/site-day over 19 day/yr from 1 sites or 5.9E+0 kg/y r to: uncertain

Air Typical: 1.4E-7 kg/site-day over 200 day/yr from 1 sites or 2.7E-5 kg/y r Worst Case: 2.7E-7 kg/site-day over 200 day/yr from 1 sites or kg/y r to: Air

Water or Air or Landfill Output 2: 6.8E-3 kg/site-day over 200 day/yr from 1 sites or 1.4E+0 kg/y r to: water, landfill or air (Air Typical: 6.6E-7 kg/site-day over 200 day/yr from 1 sites or 1.3E-4 kg/y r Worst Case: 5.3E-6 kg/site-day over 200 day/yr from 1 sites or kg/y r to: Air

Air Output 2: 6.6E-4 kg/site-day over 200 day/yr from 1 sites or 1.3E-1 kg/y r to: Air

Air Output 2: 1.4E-3 kg/site-day over 200 day/yr from 1 sites or 2.9E-1 kg/y r to: Air

Water or Incineration or Landfill Conservative: 2.0E-2 kg/site-day over 200 day/yr from 1 sites or 4.0E+0 kg/y r to: uncertain



## RELEASE TOTAL 1.2E+1 kg/y r - all sites



## OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY Tot. # of workers exposed via assessed routes: 29 Basis:

Dermal:

Exposure to Liquid High End: 8.8E+1 mg/day over 200 days/y r Number of workers (all sites) with Dermal exposure: 29 Basis:Inhalation:

Exposure to Vapor Typical: 6.6E-4 mg/day over 200 days/y r Worst Case: 3.9E-2 mg/day over 200 days/y r Number of workers (all sites) with Inhalation exposure: 29 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Inhalation:

Exposure to Vapor Typical: 6.6E-5 mg/day over 200 days/y r Worst Case: 3.9E-3 mg/day over 200 days/y r Number of workers (all sites) with Inhalation exposure: 29 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Dermal:

Exposure to Solid High End: 1.6E+2 mg/day over 200 days/y r Number of workers (all sites) with Dermal exposure: 29 Basis:

Inhalation:

Exposure to Particulate Upper Bound: 7.5E-1 mg/day over 200 days/y r Number of workers (all sites) with Inhalation exposure: 29 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Inhalation:Exposure to Vapor Typical: 3.2E-4 mg/day over 200 days/y r Worst Case: 7.6E-2 mg/day over 200 days/y r Number of workers (all sites) with Inhalation exposure: 29 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

Dermal:

Exposure to Liquid High End: 8.8E+1 mg/day over 200 days/y r Number of workers (all sites) with Dermal exposure: 29 Basis:

Inhalation:

Exposure to Vapor Typical: 1.7E-2 mg/day over 200 days/y r Worst Case: 7.9E-2 mg/day over 200 days/y r Number of workers (all sites) with Inhalation exposure: 29 Basis:



## INHALATION MONITORING DATA REVIEW 1) Uncertainty (estimate based on model, regulatory limit, or data not specific to industry): Yes 2) (a) Exposure level > 1 mg/day? N o (b) Hazard Rating for health of 2 or greater? N o Inhalation Monitoring Data Desired? N o

# A-003
Initial Review Exposure Report

for PMN P -09-7212/10/08 Page of

INITIAL REVIEW EXPOSU RE REPORT (IRExR)

Chemical ID: P090072 Reviewer: Cinalli

Results Table: Dose, Concentration, and Days Exceeded Results Summary

Exposure Scenario 1 Water Landfill Stack Air Fugitive Air Drinking Water Fish Ingestion

ADR LADD ADR LADD 7Q10 CC=100 PDM Days Exceeded LADD ADR LADD ADR LADD Release activity(ies) 2 ; exposure calculation(s) 3
mg/kg/day mg/kg/day mg/kg/day mg/kg/day μ g/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day PROC1: max acute

eco --- --- --- --- 20.21 --- --- --- --- --- ---

PROC1: max PDM --- --- --- --- 9.62 0 --- --- --- --- ---

PROC2: max acute

eco --- --- --- --- 320.75 --- --- --- --- --- ----

PROC2: max PDM --- --- --- --- 25.28 3 --- --- --- --- ---

1 Exposure scenario titles consist of release activ ity followed by exposure calculation abbreviation.

2 Release activities are from engineering report's Manufactur ing (Mfg), Processing (Proc) and Use release activity labels. Multiple release activities are combined in one exposure scenario if their releases occur at same location.

3 Exposure calculations are Acute Dose Rate (ADR), Lifetime Average Daily Dose (LADD), and Probabilistic Dilution Model (PDM). There may be one, two, or all three exposure calculations per exposure scenario. CC is the aquatic concentration of concern.

Remarks:

Fate test recommendations?: (default is NA)12/10/08 Page of

INITIAL REVIEW EXPOSU RE REPORT (IRExR)

Summary Table: Endpoints assessed12/10/08 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P090072 Assessor: Cinalli

ENVIRONMENTAL RELEASES12/10/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

WWT
REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

0.00 11. 0.21 0.21 0.00 4.94

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50 413.73 144.88 85.50 75.59 0.51 1.45 2.46 2.78

ALL 10 47.35 23.64 10.39 11.73 4.44 8.88 20.21 17.90

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 1.19E-07 1.04E-06 mg/kg/day 2.53E-09 2.21E-08 mg/kg/day

LADC pot 6.12E-06 5.35E-05 mg/L 3.02E-05 2.64E-04 mg/kg

Acute

ADR pot 1.21E-04 7.42E-04 mg/kg/day 4.50E-06 3.94E-05 mg/kg/day

SIC Code Comments:12/10/08 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P090072 Assessor:

ENVIRONMENTAL RELEASES

Scenario#:2 Number of Release Sites: 1.
Release Activity: PROC1: max PDM

Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases: 2.00 N/A N/A N/A

(kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge

Release Days/yr: 20.00 0.00/0.00 N/A N/A

Per Site Release: 0. 10 N/A/0.00 N/A N/A

(kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks:12/10/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 2 Number of Site s: 1 RELEASE ACTIVITY:PROC1: max PDM

Comments:12/10/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 2 RELEASE ACTIVITY: PROC1: max PDM12/10/08 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P090072 Assessor:

ENVIRONMENTAL RELEASES

Remarks:12/10/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 3 Number of Site s: 1 RELEASE ACTIVITY:PROC2:
max acute eco

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 1.10E-06 1.24E-05 mg/kg/day 2.33E-08 2.63E-07 mg/kg/day

LADC pot 5.64E-05 6.37E-04 mg/L 2.79E-04 3.15E-03 mg/kg

Acute

ADR pot 6.45E-04 1.46E-02 mg/kg/day 2.40E-05 2.72E-04 mg/kg/day

SIC Code Comments:12/10/08 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P090072 Assessor:

ENVIRONMENTAL RELEASES12/10/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 4 Number of Site s: 1 RELEASE ACTIVITY:PROC2: max PDM

WWT
REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

0.00 200. 0.0268 2.68E-02 0.00 4.94

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50 125.56 44.02 26.80 22.53 0.21 0.61 1.00 1.19

ALL 10 11.11 1.94 1.06 0.96 2.41 13.81 25.28 27.92

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 9.12E-07 1.03E-05 mg/kg/day 1.93E-08 2.18E-07 mg/kg/day

LADC pot 4.68E-05 5.29E-04 mg/L 2.31E-04 2.61E-03 mg/kg

Acute

ADR pot 5.09E-05 1.15E-03 mg/kg/day 1.89E-06 2.14E-05 mg/kg/day

SIC Code Comments:12/10/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 4 RELEASE ACTIVITY: PROC2: max PDM12/10/08 Page of



## LEGEND FOR NEW CHEMICAL S EXPOSURE REPORT

This new chemicals exposure report wa s prepared by the Exposure Assessment Branch (EAB) of the Economics, Exposure and Technology Division, Office of Pollution Prevention and Toxics, USEPA.

The goals of these reports are to calcula te conservative (protective) estimates of exposure endpoints for consumers, the general population, and the environment.

For each exposure scenario to industrial releases, the following three endpoints are calculated: (1) maximum possible acute concentrations and doses (2) maximum possible chronic concentrations and doses (3) for water releases ≥ 20 days, the probability of exceedence of the aquatic concentration of concern These endpoints are identified by abbreviati ons on the Release Activity line, e.g., (1) max ADR , (2) max LADD , (3) max PDM . Depending on the release inputs, these e ndpoints may be calculated and presented on the same page or different pages. That is, a release activity ID of mfg; max ADR, max PDM, max LADD indicates that all the exposure endpoints were cal culated from common manufacturing release values; conversely, a release activity ID of mfg &proc; max ADR indicates that only the maximum acute exposure values were calculated for manufacturing and proce ssing releases that occurred at the same site.

For each consumer product use exposure scenario, whether exposure is to the user directly or to the general population/environment, the maximum exposure values are calculated and presented together.

In addition to the exposure values above, EPA policy dir ects that exposure and release values be compared to criteria threshold values for Exposure-based and PBT Exposure-based cases.

Exposure-based (YX) cases (those with ≥ 100,000 kg/yr production volume) Criteria are exceeded under the following conditions: Presence in consumer product with likely exposure ≥ 3E-3 mg/kg/d exposure via air, fish ingestion or drinking water ≥ 10,000 kg/yr release to environment (post-treatment) ≥ 1,000 kg/yr release to water (post-treatment)

Persistent, Bioaccumulative, Toxic (PBT) chemical s of P2B2 rating or hi gher and production volume ≥ 20,000 kg/yr Criteria are exceeded as for YX cases, with the following differences: ≥ 2,000 kg/yr release to environment (post-treatment) ≥ 200 kg/yr release to water (post-treatment)

Bolding rules in the Report: Values for endpoints above th at are also health or eco concerns are bolded.12/19/08 Page of12/19/08 Page of

INITIAL REVIEW EXPOSU RE REPORT (IRExR)

Re marks:12/19/08 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P090072 Assessor: Sherer

ENVIRONMENTAL RELEASES

Scenario#:1 Number of Release Sites: 1.
Release Activity:

Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases: 2.31 N/A N/A N/A

(kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge

Release Days/yr: 11.00 0.00/0.00 N/A N/A

Per Site Release: 0. 21 N/A/0.00 N/A N/A

(kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks:12/19/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SCENARIO #: 1 Number of Site s: 1 RELEASE ACTIVITY:PROC1:

SIC-CODE DESCRIPTION:

SIC-CODE (S): EXPOSED POPULATION: Adult

WWT
REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

0.00 11. 0.21 0.21 0.00 4.94

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50 413.73 144.88 85.50 75.59 0.51 1.45 2.46 2.78

ALL 10 47.35 23.64 10.39 11.73 4.44 8.88 20.21 17.90

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 1.19E-07 1.04E-06 mg/kg/day 2.53E-09 2.21E-08 mg/kg/day

LADC pot 6.12E-06 5.35E-05 mg/L 3.02E-05 2.64E-04 mg/kg

Acute

ADR pot 1.21E-04 7.42E-04 mg/kg/day 4.50E-06 3.94E-05 mg/kg/day

SIC Code Comments:12/19/08 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P090072 Assessor:12/19/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SCENARIO #: 2 Number of Site s: 1 RELEASE ACTIVITY:PROC1: max PDM

WWT
REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

0.00 20. 0.1 0.10 0.00 4.94

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50 413.73 144.88 85.50 75.59 0.24 0.69 1.17 1.32

ALL 10 47.35 23.64 10.39 11.73 2.11 4.23 9.62 8.53

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 1.03E-07 9.03E-07 mg/kg/day 2.19E-09 1.91E-08 mg/kg/day

LADC pot 5.30E-06 4.63E-05 mg/L 2.62E-05 2.29E-04 mg/kg

Acute

ADR pot 5.77E-05 3.53E-04 mg/kg/day 2.15E-06 1.87E-05 mg/kg/day

SIC Code Comments:12/19/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SCENARIO #: 2 RELEASE ACTIVITY: PROC1: max PDM

SIC CODE RESULTS

COC ( μ g/L) Percent of Year COC Exceeded Number of Days COC Exceeded Release days/year Loading (kg/site/day) Waste Water Treatment (%) High/Avg Analysis

1.00 5 19 20.00 0.10 0.00 High12/19/08 Page of

INITIAL REVIEW EXPOSURE REPORT12/19/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SCENARIO #: 3 Number of Site s: 1 RELEASE ACTIVITY:PROC2: max Acute Eco

SIC-CODE DESCRIPTIO

EX POSED POPULATION: Adult

WWT
REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

0.00 19. 0.34 0.34 0.00 4.94

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50 125.56 44.02 26.80 22.53 2.71 7.72 12.69 15.09

ALL 10 11.11 1.94 1.06 0.96 30.60 175.26 320.75 354.17

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 1.10E-06 1.24E-05 mg/kg/day 2.33E-08 2.63E-07 mg/kg/day

LADC pot 5.64E-05 6.37E-04 mg/L 2.79E-04 3.15E-03 mg/kg

Acute

ADR pot 6.45E-04 1.46E-02 mg/kg/day 2.40E-05 2.72E-04 mg/kg/day

SIC Code Comments:12/19/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SCENARIO #: 3 RELEASE ACTI VITY: PROC2: max Acute Eco

SIC CODE RESULTS

COC ( μ g/L) Percent of Year COC Exceeded Number of Days COC Exceeded Release days/year Loading (kg/site/day) Waste Water Treatment (%) High/Avg Analysis

1.00 5 19 19.00 0.34 0.00 High12/19/08 Page of

INITIAL REVIEW EXPOSURE REPORT12/19/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SCENARIO #: 4 Number of Site s: 1 RELEASE ACTIVITY:PROC2: max PDM

WWT
REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

0.00 200. 0.0268 2.68E-02 0.00 4.94

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50 125.56 44.02 26.80 22.53 0.21 0.61 1.00 1.19

ALL 10 11.11 1.94 1.06 0.96 2.41 13.81 25.28 27.92

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 9.12E-07 1.03E-05 mg/kg/day 1.93E-08 2.18E-07 mg/kg/day

LADC pot 4.68E-05 5.29E-04 mg/L 2.31E-04 2.61E-03 mg/kg

Acute

ADR pot 5.09E-05 1.15E-03 mg/kg/day 1.89E-06 2.14E-05 mg/kg/day

SIC Code Comments:12/19/08 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090072

SCENARIO #: 4 RELEASE ACTIVITY: PROC2: max PDM

SIC CODE RESULTS

COC ( μ g/L) Percent of Year COC Exceeded Number of Days COC Exceeded Release days/year Loading (kg/site/day) Waste Water Treatment (%) High/Avg Analysis

1.00 38 140 200.00 2.68E-02 0.00 High

Remarks: COC exceeded for > 20 days.12/19/08 Page of12/19/08 Page of12/19/08 Page of12/19/08 Page of

Lifetime Average Daily Dose (mg/kg-day)
ADR - Acute Dose Rate (mg/kg-day)12/19/08 Page of