U.S. Environmental Protection Agency December 2010

1 List of References Published from 2007 through 2010 of Some Relevance to the Environmental Toxicity of BPA

(1) Baek, H.J.; Hwang, I.J.; Kim, K.S.; Lee, Y.D. ; Kim, H.B.; Yoo, M.S. 2007. Effects of BPA and DES on longchin goby (Chasmichthys dolichognat hus) in vitro during the oocyte maturation. Mar. Environ. Res. 64, 79–86.

(2) Bjerregaard, P.; Andersen, S.B.; Pedersen, K. L.; Pedersen, S.N.; Korsgaard, B. 2007. Orally administered bisphenol A in rainbow trout ( Oncorhynchus mykiss ): Estrogenicity, metabolism and retention. Environ. Toxicol. Chem. 26 (9), 1910–1915.

(3) Bjerregaard, L.B.; Lindholst, C.; Korsg aard, B.; Bjerregaard, P. 2008. Sex hormone concentrations and gonad histology in brown trout ( Salmo trutta ) exposed to 17 b -estradiol and bisphenol A. Ecotox. 17, 252–263.

(4) Brian, J.; Harris, C.A.; Scholze, M.; Korten kamp, A.; Booy, P.; Lamoree, M.; Pojana, G.; Jonkers, N., Marcomini, A., Sumpter, J. P. 2007. Evidence of estrogenic mixture effects on the reproductive performance of fish. Environ. Sci. Technol. 41, 337-344.

(5) Correia, A.D.; Freitas, S.; Scholze, M.; Gonçal ves, J.F.; Booij, P.; Lamoree, M.H.; Mañanós, E.; Reis-Henriques, M.A. 2007. Monograph: Mixtures of Estrogenic Chemicals Enhance Vitellogenic Response in Sea Bass. Envir on. Health Perspect. 115 (Suppl. 1), 115-121.

(6) Fini, J-B.; Dolo, L.; Cravedi, J-P.; Deme neix, B.; Zalko, D. 2009. Metabolism of the Endocrine Disruptor BPA by Xenopus laevis Tadpoles. Trends in Compar. Endocrin. Neurobio.: Ann. N.Y. Acad. Sci. 1163, 394–397.

(7) Forbes, V.E; Aufderheide, J.; Warbritton, R.; Thompson, R.; van der Hoeven, N.; Caspers, N. 2008. Effects of bisphenol A on fecundity, e gg hatchability, and j uvenile growth of Maris

Cornuarietis . Environ. Toxicol. and Chem. 27 (11), 2332–2340.

(8) Hayashi, H.; Nishimoto, A.; Oshima, N.; Iwamuro, S. 2007. Expression of the estrogen receptor alpha gene in the anal fin of Japanese medaka, Oryzias latipes , by environmental concentrations of bisphenol A. The J. of Toxicol. Sci. 32 (1), 91-96.

(9) Heimeier, R. A.; Das, B.; Buchholz, D.R.; Shi, Y. 2009. The Xenoestrogen Bisphenol A inhibits postembryonic vertebrate developm ent by antagonizing gene regulation by thyroid hormone. Endocrinology , 150, 2964-2973.

(10) Jolly, C.; Katsiadaki c , I.; Morris, S.; Le Belle b, N.; Dufour b , S.; Mayer, I.; Pottinger d

, T.G.; Scott, A.P. 2009. Detection of the anti -androgenic effect of endocrine disrupting environmental contaminants using in vivo and in vitro assays in the three-spined stickleback. Aquatic Toxicol. 92, 228–239.

(11) Kausch, U.; Alberti, M.; Haindl, S.; B udczies, J.; Bertold, H. 2008. Biomarkers for exposure to estrogenic compounds: Gene expression analysis in zebrafish ( Danio rerio ). Environ.

Tox. 23 (1), 15-24.U.S. Environmental Protection Agency December 2010

2 (12) Klecka, G.M.; Staples, C.A.; Clark, K.E.; Va n Der Hoeven, N.; Thomas, D.E.; Hentges, S.G. 2009. Exposure analysis of bisphenol A in surfa ce water systems in North America and Europe. Environ. Sci. Technol. 43 (16), 6145-6150.

(13) Koponen, P.S; Tuikka, A.; Kukkonen, J.V.K. 2007. Effects of ultraviolet-B radiation and larval growth on toxicokinetics of wa terborne bisphenol A in common frog ( Rana temporaria ) larvae. Chemosphere 66, 1323-1328.

(14) Lee, S-B.; Choi, J. 2007. Effects of bis phenol A and ethynyl estradiol exposure on enzyme activities, growth and development in the fourth instar larvae of Chironomus riparius (Diptera, Chironomidae). Ecotox. Environ. Safety 68, 84-90.

(15) Li, X.; Lin, L.; Luan, T.; Yang, L.; Lan, C. 2008. Effects of landfill leachate effluent and bisphenol A on glutathione and gl utathione-related enzymes in the gills and digestive glands of

the freshwater snail Bellamya purificata . Chemosphere 70, 1903-1909.

(16) Li, R.; Chen, G-Z.; Tam, N.F.Y.; Luan, T-G.; Shin, P.K.S.; Cheun, S.G.; Liu, Y. 2009. Toxicity of bisphenol A a nd its bioaccumulation and removal by a marine microalga Stephanadiscus hantzschii . Ecotox. Environ. Safety 72, 321-328.

(17) Lv, X.; Zhou, Q.; Song, M.; Jiang, G.; Sh ao, J. 2007. Vitellogenic responses of 17 β

estradiol and bisphenol A in male Chinese loach ( Misgurnus anguillicaudatus ). Environ. Toxicol. Pharm. 24, 155-159.

(18) Mandich, A.; Bottero, S.; Benfenati, E.; Cevasco, A.; Erratico, C. ; Maggioni, S.; Massari, A.; Pedemonte, F.; Vigano, L. 2007. In vivo exposure of carp to gr aded concentrations of bisphenol A. Gen. Comp. Endocrin. 153, 15-24.

(19) Mihaich, E.M.; Friederich, U.; Caspers, N.; Hall, A.T.; Klecka, G.M.; Dimond, S.S.; Staples, C.A.; Ortego, L.S.; Hentges, S.G. 2009. Acute and chronic toxicity testing of bisphenol A with aquatic invertebrates and plants . Ecotox. Environ. Safety 72, 1392-1399.

(20) Oehlmann, J.; Oetken, M.; Schulte-Oehlm ann, U. 2008. A critical evaluation of the environmental risk assessment for plasticizers in the freshwater environment in Europe, with special emphasis on bisphenol A and e ndocrine disruption. E nviron. Res. 108, 140-149.

(21) Oehlmann, J.; Schulte-Oehlmann, U.; Oetken, M. 2008. Letter to the editor: Superfeminization as an e ffect of bisphenol A in Marisa cornuarietis . Ecotox. Environ. Safety 69, 577-579.

(22) Olsvik, P.A.; Lie, K.K.; Sturve, J.; Hasse lberg, L.; Andersen, O.K. 2009. Transcriptional effects of nonylphenol, bisphenol A and PBDE-4 7 in liver of juvenile Atlantic cod ( Gadus

morhua ). Chemosphere 75, 360-367.U.S. Environmental Protection Agency December 2010

3 (23) Ozlem, C.A.; Hatice, P. 2008. Effects of bisphenol A on the embryonic development of sea urchin ( Paracentrotus lividus ). Environ. Toxicol. 23, 387-392.

(24) Park, K.; Kwak, I-S. 2010. Molecular eff ects of endocrine-disr upting chemicals on the Chironomus riparius estrogen-related receptor gene. Chemosphere, 934-941.

(25) Park, S-Y.; Choi, J. 2009. Genotoxic eff ects of nonylphenol and bisphenol A exposure in aquatic biomonitoring species: freshwater crustacean, Daphnia magna , and aquatic midge, Chironomus riparius . Bull. Environ. Toxicol. 83, 463-468.

(26) Ramakrishnan, S.; Wayne, N.L. 2008. Impact of bisphenol-A on early embryonic development and reproductive maturation. Reproductive Toxicology 25, 177–183.

(27) Staples, C.A.; Woodburn, K.B.; Klecka, G.M.; Mihaich, E.M.; Hall, A.T.; Ortego, L.; Caspers, N.; Hentges, S.G. 2008. Comparison of four species sensitivity distribution methods to calculate predicted no effect conc entrations for bisphenol A. Human and Ecol. Risk Assess. 14,

455-478.

(28) Staples, C., Friederich, U., Hall, T.; Kl ecka, G.; Mihaich, E.; Ortego, L.; Caspers, N.; Hentges, S. 2010. Estimating potential risks to terrestrial invertebrates and plants exposed to bisphenol A in soil amended with activated sludge biosolids. Environ. Toxicol. Chem. 29 (2),

467-475.

(29) Vajda, A.M.; Barber, L.B.; Gray, J.L.; Lopez, E.M.; Woodling, J.D.; Norris, D.O. 2008. Reproductive disruption in fish downstream from an estrogenic wastewater effluent. Environ. Sci. Technol. 42, 3407-3414.

(30) Warner, K.E.; Jenkins, J.J. 2007. Effects of 17 α -ethinylestradiol and bisphenol A on vertebral development in the fathead minnow ( Pimephales promelas ). Environ. Toxicol. Chem. 26 (4), 732-737.

Older Studies of Sub-Lethal Effects Also Cited in Table 2

(1) Andersen, H.R.; Halling-Sørensen, B.; Ku sk, K.O. 1999. A parameter for detecting estrogenic exposure in the copepod Acartia tonsa . Ecotox. Environ. Safe. 44, 56-61.

(2) Bowmer, T.; Gimeno, S. 2001. The Effects of Bisphenol-A on the Development of the Male Carp Reproductive Tract When Exposed During Se xual Differentiation – Implications for Test Design and Risk Assessment. Unpublishe d TNO Report. [As cited in EU. 2008. European Union Updated Risk Assessment Report. Bisphenol A, CAS No: 80-05-7 . Institute for Health and Consumer Protection, European Chemicals Bu reau, European Commission Joint Research Centre, 3rd Priority List, Luxe mbourg: Office for Official Publications of the European Communities.]U.S. Environmental Protection Agency December 2010

4 (3) Duft, M.; Schulte-Oehlmann, U.; Weltje, L. ; Tillman, M.; Oehlmann, J. 2003. Stimulated embryo production as a parameter of estrogeni c exposure via sediments in the freshwater

mudsnail Potamopyrgus antipodarum . Aquatic Toxicol. 64, 437-449.

(4) Furuya, M.; Adachi, K.; Kuwahara, S.; Ogawa, K.; Tsukamoto, Y. 2006. Inhibition of male chick phenotypes and spermatogenesis by Bisphenol-A. Life Sciences 78, 1767-1776.

(5) Japanese Ministry of the Environment. 2006. Results of Assay and Tests in Evaluation of the Endocrine Disrupting Activi ties in Fish (Medaka). http://www.env.go.jp/en/chemi/ed/rt_medaka.pdf

.

(6) Jobling, S.; Casey, D.; Rodgers-Gray, T.; Oe hlmann, J.; Schulte-Oehlmann, U.; Pawlowski, S.; Baunbeck, T.; Turner, A.P.; Tyler, C.R. 2004. Comparative responses of molluscs and fish to environmental estrogens and an estrogen ic effluent. Aquat. Toxicol. 66, 207-222.

(7) Kashiwada, S.; Ishikawa, H.; Miyamoto, N.; Ohnishi, Y.; Magara, Y. 2002. Fish test for endocrine-disruption and estimation of water quality of Japanese rivers. Water Res. 36, 2161-

2166.

(8) Kwak, H.I.; Bae, M.O.; Lee, M.H.; Lee, Y.S. ; Lee, B.J.; Kang, K.S.; Chae, C.H.; Sung, H.J.; Shin, J.S.; Kim, J.H.; Mar, W.C.; Sheen, Y.Y.; Cho, M.H. 2001. Effects of nonylphenol, bisphenol-A, and their mixture on th e viviparous swordtail fish ( Xiphophorus helleri ). Environ. Toxicol. Chem. 20(4), 787-795.

(9) Levy, G.; Lutz, I.; Krüger, A.; Kloas, W. 2004. Bisphenol A i nduces feminization in Xenopus laevis tadpoles. Environ. Res. 94, 102-111.

(10) Marcial, H.S.; Hagiwara, A.; Snell, T.W. 2003. Estrogenic compounds affect development of harpacticoid copepod Tigriopus japonicus . Environ. Toxicol. Chem. 22(12), 3025-3030.

(11) Metcalfe, C.D.; Metcalfe, T.L.; Kipariss is, Y.; Koenig, B.G.; Khan, C.; Hughes, R.J.; Croley, T.R.; March, R.E.; Potter, T. 2001. Estroge nic potency of chemicals detected in sewage treatment plant effluents as determined by in vivo assays with Japanese medaka ( Oryzias latipes ). Environ. Toxicol. Chem. 20, 297-308.

(12) Oehlmann, J.; Schulte-Oehlmann, U.; Tillmann, M.; Markert, B. 2000. Effects of endocrine disruptors on prosobranch snails (Mollusca: Ga stropoda) in the laborator y. Part I: Bisphenol-A and Octylphenol as xenoestr ogens. Ecotoxicology 9, 383-397.

(13) Oehlmann, J.; Schulte-Oehlmann, U.; Bachmann, J.; Oetken, M.; Lutz, I. ; Kloas, W.; Ternes, T.A. 2005. Bisphenol A Induces Superfemin ization in the Ramshorn Snail (Gastropoda: Prosobranchia) at Environmentally Relevant Concentrations. Environ. Health Perspect. 114 (Suppl. 1), 127-133.U.S. Environmental Protection Agency December 2010

5 (14) Rhodes JE, Wolf JC and van der Hoeven N (2007). Bisphenol A: par tial life-cycle toxicity test with the fathead minnow, Pimephales promelas . ABC Laboratories, Inc. and Experimental Pathology Laboratories, Inc., ABC Study numbe r 48972 (Unpublished study). [As cited in EU.

2008. European Union Updated Risk Assessment Report. Bisphenol A, CAS No: 80-05-7

. Institute for Health and Consumer Protec tion, European Chemicals Bureau, European

Commission Joint Research Cent re, 3rd Priority List, Luxe mbourg: Office for Official Publications of the European Communities.]

(15) Tabata, A.; Kashiwada, S.; Ohnishi, Y.; Is hikawa, H.; Miyamoto, N.; Itoh, M.; Magara, Y. 2001. Estrogenic influences of estradiol-17ß, p-nonylphenol a nd bisphenol-A on Japanese Medaka ( Oryzias latipes ) at detected environmental con centrations. Water Science Technol. 43(2), 109-116.

(16) Watts, M.M.; Pascoe, D.; Carroll, K. 2001. Survival and precopulatory behaviour of Gammarus pulex (L.) exposed to two xenoestrogens. Water Res. 35(10), 2347-2352.

(17) Watts, M.M.; Pascoe, D.; Carroll, K. 2003. Chronic exposure to 17 α -ethinylestradiol and bisphenol A - effects on devel opment and reproduction in th e freshwater invertebrate Chironomus riparius (Diptera: Chironomidae). Aquatic Toxicol. 55, 113-124.

(18) Yokota, H.; Tsuruda, Y.; Maeda, M.; Os hima, Y.; Tadokoro, H.; Nakazono, A.; Honjo, T.; Kobayashi, K. 2000. Effect of bisphenol-A on the early life stage in Japanese medaka ( Oryzias latipes ). Environ. Toxicol. Chem. 19(7), 1925-1930.