2,4-D



### Date:

Subject: Dietary Exposure and Risk Assessment DP #: 0413003



### UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
WASHINGTON, D.C. 20460



### August 8, 2013 OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION



### 2,4-D

. Acute and Chronic Aggregate Dietary (Food and Drinking Water) Exposure and Risk Assessment for t he Section 3 Registration Action on Herbicide-Tolerant Fie ld Com and Soybean.

PC Code : 030001 Decision No

. : 

## l/'/?951
Petition No.: NA DP Barcode : D413003 Registration Nos.: NA Regulatory Action: Section 3 Registration CaseNo.: NA Risk Assessment Type: Dietary TXRNo.: NA CAS No.: 94-75-7 MRID No.: None 40 CFR : 180.142

From:

Through:

To: Alexandra LaMay, Biologist Risk Assessment Branch 

## V II Health Effects Di vision (7509P)

# t~/~~**~**


# -

Nancy Dodd

, Chemist .//

# 41/]~ 1.{)...,;-z/::/""
Meheret Negussie, Chemist 

## NJh e

. 

# .--J**,A}~<::::....** Dietary Exposure Science Advisury ouncil (fS'ESAC)

and

# (IJ/JD~ Michael Metzger, Branch Chief 

# i**~~** 

# ;{

. Health Effects Division (7509P) '

. · '

Michael Walsh Registration Division (7505P)

The current dietary assessment upda tes the most recent die t ary assessment for 2,4- dichlorophenoxyacetic acid (2,4-D) (Memo, T. 

### Jimerson, D315512, 4118/05) and incorporates recently revised toxico lo gica l FQP A/uncertain ty factors, points of departure, the new version of DEEM, and updated drinking water numbe rs fo r 2,4-D. This update is done in support of proposed new us es of2,4-D choline on 2,4-D tol erant field com and soybean

.

Executive Summary

Acute and chronic aggregate (food + die t ary drinking water) exposure and risk assessments were conducted using the Dietary Expo sure E valuat ion Model software with the Food Commodity In take Database (DEEM-FCID) Version 3

. 1 6. This software uses 2003-2008 food consumption 

## data from the U.S. Department of Agr i culture's (USDA's) National Health and Nutrition Examination Survey, What We Eat in America, (NHANES/WWEIA). The current assessment is being conducted i n support of proposed new uses of2,4-D choline on 2,4-D tolerant field com

Page 1 of222

, 4-D Dietary Exposure and Risk Assessment DP 

### # : D413003



### and soybean. This assessment includes the proposed uses and all existing uses of 2,4 D. This memorandum was reviewed by two peer reviewers of the DESAC per DESAC SOP 2012. 1.

The dietary analyses incorporated the drinking water estimates provided b y Environmental Fate and E ffects Division (EFED). The estimated drinking water concentrations ( E DWCs) were estimated using the Pesticide Root Zone Model/Exposure Analysis Modeling System (PRZMJ EXAM S) models for s urface water and Screening Concentration In GROund Water model (SCI-GROW) for ground water. For ground water, the maximum concentration detected from monitoring data was 15 Jlg /L

. For surface water, the 1-in-10 year acute (peak) and annual
average concentrations are 136 and 23 Jlg/L, respectively (0403774 and 404562, F. Khan

, 10/2/20 12). EFED in dicat ed t hat t he estimated drinkin g water exposure for the acute assessment should be 136 ppb, t he 1 in 10 year annual peak exposure based on the MS corn scenario. The chronic assessment should use the 1 in 10 yea r annual mean value of 23 ppb (email communication between Faruque K.han/EF E D and Alexandra L aMay / HED, 10/03/12).

The acute analysis assumed 100% crop treated (CT) for all commodities and tolerance-level
exposure values for all commodities except for soybean. The highest average field trial (HAFT)

va lue for residues of 2,4-dichlorophenol (2,4-DCP) and 

### Yz LOD value for residue of parent 2

, 4-D

was used for soy bean (see description of residues of concern in Section II). Empirical and default processing factors were u sed as appropriate. The resulting acute food plu s drinking water risk estima t es are not of concern to HED [:S1 00% acute population-adjusted dose (aPAD)] at the 95th percentile of the exposure distr ibution for all population s ub groups of intere st. T he resulting
acute risk est imat e for children 1 to 2 years old, the subgroup with the greatest exposure, was 14% of the aP AD at the 95th percentile of the exposure.

The chronic dietary analysis was a lso unrefined, making use of the following: tolerance-level
exposure values for all commodities excep t soybean (2,4-DCP HAFT residue was used for soybean), and 100 %CT information for all commodities

, including field corn and soybean. Empir i cal and default processing factors were us e d as ap p ropriate. T h e r esul t i ng chronic r isk estimates are not of concern to HED. The most highly exposed population was children 1 to 2
years old

, utilizing 15% of the chronic PAD ( cP AD).



### I. Introduction

Dietary risk assessment incorporates both exposure and tox icity of a given pesticide. For acute and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose (i.e., the dose which HED has concluded will result in no unreasonable adverse health effects). This dose is referred to as t he PAD. The PAD is equivalent to a point-of-departure [POD ; e.g.,

no

- observable-adverse-effect-level (NOAEL) ) divided by the required uncertainty or safety factors. For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk exceeds 100% ofthe PAD. References which discuss the acute and chronic risk assessments in more detail are available on the EPA/pesticides web site: "Ava ilable Information on Assessing Exposure from Pesticides, A User's Guide," 6/21/2000, web link: htt p : // www.epa

. gov / fednzstr / EPA-PEST / 2000 / J uly / Da y

- 1 2 / 606l .p df ; or see SOP 99.6 (8 / 20 / 99).

The most recent dietary risk assessment for 2,4-D was conducted by Toiya Jimer son (4 / 18/05, DP Number 315512).

Page 2 of222,4

- D Dietary Exposure and Risk Assessment DP #: D413003

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Page 3 of 22 

### II. Residue Information

Residues of Concern : HED’s Metabolism Assessment Review Committee (MARC) determined that the residue of toxicological concern to be included in crop and livestock tolerances and in dietary risk assessments (food and water) is 2,4

- D, both free and conjugated, determined as the acid ( Memo, T. Jimerson

, 10/13/04 ).

In the risk assessment s for 2,4

- D

- tolerant field corn and soybean (D 400085 , D. Drew, 7/11 /1 3 and D394981, A. LaMay, 10/27/11) , it was determined that the metabolite 2,4

- DCP also be included as a residue of concern for dietary risk assessment purposes for 2,4

- D tolerant field corn and soybean a s there are greater amounts of 2,4

- DCP found in resistant crop compared to non

resistant crop. Since 2,4

- DCP sh ows a similar toxicity profile to 2,4

- D, comparing 2,4

- DCP residues to 2,4

- D endpoints would be protective for risk assessment purposes.

Concerning transgenic field corn, a s the combined residues of 2,4

- D and 2,4

- DCP found in transgenic field corn food items are less than the tolerances of parent only found in non

transgenic field corn, using field corn tolerance

- level values for 2,4

- D in the acute and chronic dietary analyses are protective of residues of 2,4

- D and 2,4

- DCP in transgenic field corn

.

C oncerning transgenic soybean, the combined 2,4

- D and 2,4

- DCP residues were used for the acute and chronic dietary analyses as the combined residues found in tolerant soybean were greater than the tolerance of parent only for soybean. Residue levels of par ent 2,4

- D in/on soybean were non

- detectable, thus estimated 2,4

- D residues (at 1⁄2 LOD of 0.003 ppm, or 0.0015 ppm) were added to the 2,4

- DCP highest average field trial residue ( HAFT is 0.047 ppm) to be used in the acute and chronic dietary analyses. Please refer to D 400085 (D. Drew, 7/11 /1 3 ) for more information

.
Also, as the combined residues of 2,4

- D and 2,4

- DCP found in transgenic corn feed items are lower than those residues expected in other crop feed commodities, the addition of corn feedstuff s to the livestock diet would not increase the dietary burden. The existing livestock commodity tolerances are adequate to cover the use on feedstuffs of herbicide

- tolerant field corn. A livestock feeding/grazing restriction for the soybean use is propos ed; therefore, the current tolerances for residues of 2,4

- D on soybean feedstuffs are not being reevaluated at this time.

Established

/Recommended Tolerances : 2,4

- D tolerances have been established in numerous plant commodities, crop groups, processed products, livestoc k commodities, fish, and shellfish at 40 CFR §180.142. No new or revised tolerances are required to support the proposed new use on 2,4

- D tolerant field corn and soybean (D 400085 , D. Drew

, 7/11 /1 3 and D394981, A. LaMay, 10/27/11).

Residues U

sed in the Acute and Chronic Analys e s : T olerance

- level residues were used as exposure values for all commodities in the acute assessment with the exception of soybean . The 2,4

- DCP HAFT residue for transgenic soybean was used in the assessment. It was assumed that 100% of all crops had been treated. Note that this acute dietary analysis has changed from the previous dietary assessment (T. Jimerson, D315512, 4/18/05) in several ways: (1) use of tolerance

- level residues instea d of HAFT for citrus, (2) use of tolerances

- level residues instead of average field trial residues for potato, (3) inclusion of soybean residue values (HAFT value of 2,4

- DCP and 1⁄2 LOD value for 2,4

- D2,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 4 of 22 

### combined residue for transgenic soybean) , (4) use of tol erance

- level residues for all livestock commodities

, including milk

, ( 5 ) inclusion of all food items for crop groups for which tolerances have been set (previously certain crops were excluded ; see D280885, J. Tyler, 2002 for more information)

, (6) inclusion of default processing factors, and ( 7 ) inclusion of the drinking water estimates provided by EFED

. This acute dietary exposure assessment is considered to be

un refined.

In the chronic dietary assessment, tolerance

- level exposure values wer e used for all commodities except soybean

. Concerning soybeans, the HAFT field trial residue of metabolite 2,4

- DCP was used. It was assumed that 100% of all crops had been treated. Note that this chronic dietary analysis has changed from the previous di etary assessment in several ways: (1) inclusion of tolerance

- level residues for all plant and animal commodities, including milk, (2) inclusion of herbicide

- tolerant crop residue values, (3) use of 100% CT for all commodities

, (4) inclusion of all food items for crop groups for which tolerances have been set, (5) inclusion of default processing factors, and ( 6 ) inclusion of the highest modeled surface water concentration for drinking water

. This chronic dietary assessment is c onsidered to be un refined.

The DEEM 7.81 default concentration factors were used for applicable commodities, as appropriate.

To further refine the 2,4

- D dietary exposure and risk estimates, HED could use %CT

, anticipated residues , or monitoring data , whe re available, in the acute and chronic dietary exposure
assessment

. III. Percent Crop Treated

Percent crop treated (%CT) data were not applied to the acute and chronic assessment s ; 100% CT was assumed for all commodities

, including field corn and soybean, in both analyses

.

IV

. Estimated Drinking Water Concentrations

D rinking water residues were incorporated directly into the acute and chronic dietary analyses ( “water, direct, all sources” and “water, indirect, all sources”) and were provided by EFED ( D403774 and 404562, F. Khan, 10/2/2012 ). The EDWCs were estimated for ground water using the Screening Concentration in Ground Water ( SCIGROW ) model and for surface water using the Pesticide Root Zone Model ( 

### PRZM ) / Exposure Analysis Modeling System ( EXAMS ) for 2,4

- D

. Monitoring data are also available.

EDWCs of 136 ppb and 23 ppb were used in the acute and chronic analys e s, respectively

.

Table 1 . Estimated Concentrations of 2,4

- D in Drinking Water.
Drinking Water Source Estimated Drinking Water Concentrations (ppb) Acute Chronic

Surface Water 136 23

Groundwater 15



### V. DEEM

- FCID  

### Program and Consumption Information2,4

- D Dietary Exposure and Risk Assessment DP #: D413003

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Page 5 of 22 

### 2,4

- D acute and chronic dietary exposure and risk a ssessments were conducted using DEEM

FCID  

### ( Ver

. 3.16 ), which incorporates consumption data from USDA’s NHANES/WWEIA (2003

- 2008 data). The data are based on the repor ted consumption of more than 20,000 individuals over two non

- consecutive survey days. Foods “as consumed” (e.g., apple pie) are linked to EPA

- defined food commodities (e.g., apples, peeled fruit

- cooked; fresh or N/S; baked; or wheat flour

- cooked; fres h or N/S, baked) using publicly available recipe translation files developed jointly by USDA/ARS and EPA. For chronic exposure assessment, consumption data are averaged for the entire U.S. population and within population subgroups. However, for acute

ex posure assessment, consumption data are retained as individual consumption events. Based on analysis of the 2003

- 2008 WWEIA consumption data, which took into account dietary patterns and survey respondents, HED concluded that it is most appropriate to rep ort risk for the following population subgroups: the general U.S. population, all infants (<1 year old), children 1

- 2, children 3

- 5, children 6

- 12, youth 13

- 19, adults 20

- 49, females 13

- 49, and adults 50

- 99 years old.

For acute exposure assessments, indiv idual one

- day food consumption data are used on an individual

- by

- individual basis. The reported consumption amounts of each food item can be multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a deterministic e xposure assessment, or “matched” in multiple random pairings with residue values and then summed in a probabilistic assessment. The resulting distribution of exposures is expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating relevant commodities/food forms) and a per

- capita (i.e., those who reported eating the relevant commodities as well as those who did not) basis. In accordance with HED policy, per capita exposure and risk are reported for analyse s.

For chronic dietary exposure assessment, an estimate of the residue level in each food or food

form (e.g., orange or orange juice) on the food commodity residue list is multiplied by the average daily consumption estimate for that food/food form to produce a residue i ntake estimate. The resulting residue intake estimate for each food/food form is summed with the residue intake estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated exposure. Exposure is expressed in mg/kg body weight/day and as a percent of the cPAD. This procedure is performed for each population subgroup.

V I

. Toxicological Information

The toxicological endpoints for dietary risk assessment are summarized below in Table 2

.

Table 2 . Summary of Toxicological Doses and Endpoints for 2,4

- D for Use in Dietary Risk Assessments

Exposure/ Scenario Point of

Departure Uncertainty/FQP

A Safety Factors RfD, PAD,

Level of Concern for Risk Assessment Study and Toxicological Effects

Acute Dietary (General Population, including Infants and Children) NOAEL= 67

mg/kg/day UF A = 10x

UF H = 10x FQPA SF= 1x a RfD = 0.67

mg/kg/day

aPAD = 0.67 mg/kg/day Acute Neurotoxicity Study

– Rat

MRID 43115201 (1994) LOAEL = 227 mg/kg/day based on slight gait abnormalities (forepaw flexing and knuckling) and increased incidence of incoordination.2,4

- D Dietary Exposure and Risk Assessment DP #: D413003

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Page 6 of 22 Table 2 . Summary of Toxicological Doses and Endpoints for 2,4

- D for Use in Dietary Risk Assessments

Exposure/ Scenario Point of

Departure Uncertainty/FQP

A Safety Factors RfD, PAD,

Level of Concern for Risk Assessment Study and Toxicological Effects

Acute Dietary (Females 13

- 49 years of age) NOAEL = 25

mg/kg/day UF A = 10x

UF H = 10x FQPA SF= 1x a RfD = 0.25

mg/kg/day

a PAD = 0.25 mg/kg/day Developmental Toxicity Study

– Rat

MRID 00130407, 00130408 (1983) Developmental LOAEL = 75 mg/kg/day based on fetal skeletal abnormalities (14 th rudimentary ribs )

Chronic Dietary (All Populations) NOAEL= 21

mg/kg/day UF A = 10x

UF H = 10x FQPA SF = 1x cRfD = 0.2 1

mg/kg/day

cPAD = 0.2 1 mg/kg/day Extended 1

- generation reproduction

( Crl:CD(SD) rat) MRID 47972101 (2010) Parental LOAEL= 800/600 ppm (males 55.6 mkd; females 46.7 mkd ), based on kidney toxicity manifested as increased kidney weights and increased incidence of degeneration of the proximal convoluted tubules

. Cancer (oral, dermal, inhalation) Classification: Group D

- Not Classifiable as to Human Carcinogenicity. That is, the

evidence is inadequate and cannot be interpreted as showing either the presence or absence of a carcinogenic effect. Point of Departure (POD) = A data point or an est imated point that is derived from observed dose

- response data and used to mark the beginning of extrapolation to determine risk associated with lower environmentally relevant human exposures. NOAEL = no observed adverse effect level. LOAEL = lowest obse rved adverse effect level. UF = uncertainty factor. UF A = extrapolation from animal to human (interspecies). UF H = potential variation in sensitivity among members of the human population (intraspecies). FQPA SF = FQPA Safety Factor. PAD = population adjusted dose (a = acute, c = chronic). RfD = reference dose. MOE = margin of exposure. LOC = level of concern. N/A = not applicable.



### V I I

. Results/Discussion

Acute and c hronic analyses were performed using DEEM

- FCID (ver. 3.16 ) which estimate s the dietary exposure of the U.S. population and various population subgroups. The results reported are for the general U.S. p opulation, all infants (<1 year old), children 1

- 2 years old , children 3

- 5 years old , children 6

- 12 years old , youth 13

- 19 years old , females 13

- 49 years old , adults 20

- 49 years old , and adults 50

- 99 years old

. The resulting acute food plus drinking water risk estimates are not of concern to HED ( ≤ 100% aPAD) at the 95 th 

### percentile of the exposure distribution for all p opulation subgroups of interest. T he res ulting acute risk estimate for children 1 to 2 years old, the subgroup with the greatest
exposure , was 14 % of the aPAD at the 95 th 

### percentile of the exposure

. The resulting chronic food plus drinking water risk estimates are not of concern to HED. The most highly exposed
popu lation was children 1 to 2 years old utilizing 15 % of the cPAD. See Table 3 below for a summary of the results of the dietary assessment.

Table 3 . Summary of Dietary (Food and Drinking Water) Exposure Risk for 2,4

- D

.

Population Subgroup Acute Dietary (95 th Percentile) Chronic Dietary Cancer2,4

- D Dietary Exposure and Risk Assessment DP #: D413003

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Page 7 of 22 Dietary Exposure (mg/kg/day) % aPAD * Dietary Exposure (mg/kg/day) % cPAD* Dietary Exposure (mg/kg/day) Risk

General U.S. Population 0.03 2197 4.8 0.0 09882 4.7

N/A N/A All Infants (<1 year old) 0.0 40354 6.0 0.008 879 4.2

Children 1

- 2 years old 0.09 5100 14 0.0 30838 1 5

Children 3

- 5 years old 0.07 7053 1 1 0.025 920 12

Children 6

- 12 years old 0.04 4063 6. 6 0.01 5028 7.2

Youth 13

- 19 years old 0.03 0918 4. 6 0.0 09103 4.3

Adults 20

- 49 years old 0.025 487 3.8 0.00 7842 3.7

Adults 50

- 99 years old 0.02 1883 3. 3 0.007 282 3.5

Females 13

- 49 years old 0.02 5718 10 0.00 7453 3.5

*The values for the highest exposed population for each type of risk assessment are bolded.



### VI I I

. Characterization of Inputs/Outputs

The acute and chronic analyse s assumed tolerance

- level residues and 100% CT . To further refine the 2,4

- D dietary exposure and risk estimates, %CT, anticipated residues, or monitoring data could be used in the acute and chronic dietary exposure assessment s

.

IX

. Conclusions

The acute and chronic exposure and risk assessments were conducted using DEEM

- FCID, ver. 3.16

. DEEM

- FCID incorporates food consumption data from the NHANES/WWEIA ( 2003

- 2008 data ).

The EDWCs were estimated for ground water using the SCI

- GROW model and for surface water using PRZM/EXAMS

. For ground water, the maximum concentration from monitoring data is 15 μg/L. For surface water, the 1

- in

- 10 year acute (peak) and annual average concentrations are 136 and 23 μg/L, respectively. EDWC s of 136 ppb and 23 were used in the acute and chronic analyses, respectively.

The acute analysis assumed tolerance

- level residues (except soybeans) and 100% CT

. The acute analysis also incorporated the drinking water estimates provided by EFED. Empirical and default processing factors were used as appropriate. The resulting acute food plus drinking water risk estimates are not of concern to HED ( ≤ 100% aPAD) at the 95 th 

### percentile of the exposure distribution for all population subgroups of inter est

. The res ulting acute risk estimate for children 1 to 2 years old (the subgroup with the greatest exposure ) was 14 % of the aPAD at the 95 th 

### percentile of the exposure.

The chronic analyses assumed tolerance

- level residues (except soybeans) and 100% CT for all commodities . The chronic analysis also incorporated the drinking water estimates provided by EFED

. Empirical and default processing factors were used as appropriate. The resulting chronic2,4

- D Dietary Exposure and Risk Assessment DP #: D413003

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Page 8 of 22 

### risk estimates are not of concern to HED. The most highly exposed population was all children 1 to 2 years old utilizing 15 % of the cPAD.

Both acute and chronic dietary analyses are unrefined and conservative.

Attachment 1 : DEEM

- FCID  A cute Residue File. Attachment 2 : DEEM

- FCID  Acute Exposure and Risk Estimates

. Attachment 3 : DEEM

- FCID  Chronic Residue File

. Attachment 4 : DEEM

- FCID  Chronic Exposure and Risk Estimates

.

cc: A. LaMay (RAB VII ) RDI: DE SAC Reviewers : 06/20132,4

- D Dietary Exposure and Risk Assessment DP #: D413003

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Page 9 of 22 

### Attachment 1 : DEEM

- FCID  

### A cute R esidue F ile

.

U.S. EPA Ver. 3.16, 03

- 08

- d
DEEM

- FCID Acute analysis for 2,4

- D Residue file name: C: \ Documents and Settings \ ALEMAY \ My Documents \ 24D GMO corn \ 2012 dietary assessment \ November 2012 update new DEEM \ 24D_ACUTE_SCREEN_TOLERANCE FOR ALL_061113.R08 Analysis Date 06

- 12

- 2013 Residue file dated: 06

- 12

- 2013/14:33:00 Reference dose: aRfD = 0.67 mg/kg bw/day NOEL = 67 mg/kg bw/day

---------------------------------------------- ------------------------------------ EPA Crop Def Res Adj.Factors Comment Code Grp Food Name (ppm) #1 #2

---------- ---- ------------------------------- ---------- ------ ------ ------- 1400003000 14 Almond 0.200000 1.000 1.000 1400003001 14 Almond

- babyfood 0.200000 1.000 1.000 1400004000 14 Almond, oil 0.200000 1.000 1.000 1400004 001 14 Almond, oil

- babyfood 0.200000 1.000 1.000 0401005000 4A Amaranth, leafy 0.400000 1.000 1.000 1100007000 11 Apple, fruit with peel 0.050000 1.000 1.000 1100008000 11 Apple, peeled fruit 0.050000 1.000 1.000 1100008001 11 Apple, peeled fruit

- babyfood 0.050000 1.000 1.000 1100009000 11 Apple, dried 0.050000 8.000 1.000 1100009001 11 Apple, dried

- ba byfood 0.050000 8.000 1.000 1100010000 11 Apple, juice 0.050000 1.000 1.000 1100010001 11 Apple, juice

- babyfood 0.050000 1.000 1.000 1100011000 11 Apple, sauce 0.050000 1.000 1.000 1100011001 11 Apple, sauce

- babyfood 0.050000 1.000 1.000 1202012000 12B Apricot 0.050000 1.000 1.000 1202012001 12B Apricot

- babyfood 0.050000 1.000 1.000 1202013000 12B Ap ricot, dried 0.050000 6.000 1.000 1202014000 12B Apricot, juice 0.050000 1.000 1.000 1202014001 12B Apricot, juice

- babyfood 0.050000 1.000 1.000 0103015000 1CD Arrowroot, flour 0.100000 1.000 1.000 0103015001 1CD Arrowroot, flour

- babyfood 0.100000 1.000 1.000 0103017000 1CD Artichoke, Jerusalem 0.100000 1.000 1.000 0401018000 4A Arugula 0.400000 1.000 1.000 95000 19000 O Asparagus 5.000000 1.000 1.000 9500020000 O Avocado 0.050000 1.000 1.000 0902021000 9B Balsam pear 0.050000 1.000 1.000 1500025000 15 Barley, pearled barl ey 2.000000 1.000 1.000 1500025001 15 Barley, pearled barley

- babyfood 2.000000 1.000 1.000 1500026000 15 Barley, flour 2.000000 1.000 1.000 1500026001 15 Barley, flour

- babyfood 2.000000 1.000 1.000 1500027000 15 Barley, bran 4.000000 1.000 1.000 0603030000 6C Bean, black, seed 0.050000 1.000 1.000 0602031000 6B Bean, broad, succulent 0.050000 1.000 1.000 0603032000 6C Bean, broad, seed 0.050000 1.000 1.000 0602033000 6B Bean, cowpea, succulent 0.050000 1.000 1.000 0603034000 6C Bean, cowpea, seed 0.050000 1.000 1.000 0603035000 6C Bean, great no rthern, seed 0.050000 1.000 1.000 0603036000 6C Bean, kidney, seed 0.050000 1.000 1.000 0602037000 6B Bean, lima, succulent 0.050000 1.000 1.000 0603038000 6C Bean, lima, seed 0.050000 1.000 1.000 0603039000 6C Bean, mung, seed 0.050000 1.000 1.000 0603040000 6C Bean, navy, seed 0.050000 1.000 1.000 0603041000 6C Bean, pink, seed 0.050000 1.000 1.000 0603042000 6C Be an, pinto, seed 0.050000 1.000 1.000 0601043000 6A Bean, snap, succulent 0.050000 1.000 1.000 0601043001 6A Bean, snap, succulent

- babyfood 0.050000 1.000 1.000 3100044000 31 Beef, meat 0.300000 1.000 1.000 3100044001 31 Beef, meat

- babyfood 0.300000 1.000 1.000 3100045000 31 Beef, meat, dried 0.300000 1.920 1.000 3100046000 31 Beef, meat byproducts 4.000000 1.000 1.000 31000 46001 31 Beef, meat byproducts

- babyfood 4.000000 1.000 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

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Page 10 of 22 3100047000 31 Beef, fat 0.300000 1.000 1.000 3100047001 31 Beef, fat

- babyfood 0.300000 1.000 1.000 3100048000 31 Beef, kidney 4.000000 1.000 1.000 3100049000 31 Beef, liver 0.300000 1.000 1.000 3100049001 31 Beef, liver

- babyfood 0.300000 1.000 1.000 0101050000 1AB Beet, garden, roots 0.100000 1.000 1.000 0101050001 1AB Beet, garden, roots

- babyfood 0.100000 1.000 1.000 0200051000 2 Beet, garden, tops 0.100000 1.000 1.000 0101052000 1A Beet, sugar 0.100000 1.000 1.000 0101052001 1A Beet, s ugar
- babyfood 0.100000 1.000 1.000 0101053000 1A Beet, sugar, molasses 0.100000 1.000 1.000 0101053001 1A Beet, sugar, molasses

- babyfood 0.100000 1.000 1.000 1301055000 13A Blackberry 0.200000 1.000 1.000 1301056000 13A Blackberry, juice 0.200000 1.000 1.000 1301056001 13A Blackberry, juice

- babyfood 0.200000 1.000 1.000 1302057000 13B Blueberry 0.2000 00 1.000 1.000 1302057001 13B Blueberry

- babyfood 0.200000 1.000 1.000 1301058000 13A Boysenberry 0.200000 1.000 1.000 1400059000 14 Brazil nut 0.200000 1.000 1.000 0501061000 5A Broccoli 0.400000 1.000 1.000 0501061001 5A Broccoli

- babyfood 0.400000 1.000 1.000 0501062000 5A Broccoli, Chinese 0.400000 1.000 1.000 0502063000 5B Broccoli raab 0.400000 1.000 1.000 0501064000 5A Brussels sprouts 0.400000 1.000 1.000 0101067000 1AB Burdock 0.100000 1.000 1.000 1400068000 14 Butternut 0.200000 1.000 1.000 0501069000 5A Cabbage 0.400000 1.000 1.000 0502070000 5B Cabbage, Chinese, bok choy 0.400000 1.000 1.000 0501071000 5A Cabbage, Chinese, napa 0.400000 1.000 1.000 0501072000 5A Cabbage, Chines e, mustard 0.400000 1.000 1.000 0901075000 9A Cantaloupe 0.050000 1.000 1.000 0402076000 4B Cardoon 0.400000 1.000 1.000 0101078000 1AB Carrot 0.100000 1.000 1.000 0101078001 1AB Carrot

- babyfood 0.100000 1.000 1.000 0101079000 1AB Carrot, juice 0.100000 1.000 1.000 1400081000 14 Cashew 0.200000 1.000 1.000 0103082000 1CD Ca ssava 0.100000 1.000 1.000 0103082001 1CD Cassava

- babyfood 0.100000 1.000 1.000 0501083000 5A Cauliflower 0.400000 1.000 1.000 0101084000 1AB Celeriac 0.100000 1.000 1.000 0402085000 4B Celery 0.400000 1.000 1.000 0402085001 4B Celery

- babyfood 0.400000 1.000 1.000 0402086000 4B Celery, juice 0.400000 1.000 1.000 0402087000 4B Celtuce 0.400000 1.000 1.000 0902088000 9B Chayote, fruit 0.050000 1.000 1.000 1201090000 12A Cherry 0.050000 1.000 1.000 1201090001 12A Cherry

- babyfood 0.050000 1.000 1.000 1201091000 12A Cherry, juice 0.050000 1.500 1.000 1201091001 12A Cherry, juice

- babyfood 0.050000 1.500 1.000 1400092000 14 Chestnut 0.200000 1.000 1.000 0603098000 6C Chickpea, seed 0.050000 1.000 1.000 0603098001 6C Chickpea, seed

- babyfood 0.050000 1.000 1.000 0603099000 6C Chickpea, flour 0.050000 1.000 1.000 0101100000 1AB Ch icory, roots 0.100000 1.000 1.000 0200101000 2 Chicory, tops 0.100000 1.000 1.000 0902102000 9B Chinese waxgourd 0.050000 1.000 1.000 0302103000 3B Chive, fresh leaves 0.050000 1.000 1.000 0401104000 4A Chrysanthemum, garland 0.400000 1.000 1.000 1001106000 10A Citron 3.000000 1.000 1.000 1001107000 10A Citrus hybrids 3.000000 1.000 1.000 10011 08000 10A Citrus, oil 3.000000 1.000 1.000 0502117000 5B Collards 0.400000 1.000 1.000 1500120000 15 Corn, field, flour 0.050000 1.000 1.000 1500120001 15 Corn, field, flour

- b abyfood 0.050000 1.000 1.000 1500121000 15 Corn, field, meal 0.050000 1.000 1.000 1500121001 15 Corn, field, meal

- babyfood 0.050000 1.000 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 11 of 22 1500122000 15 Corn, field, bran 0.050000 1.000 1.000 1500123000 15 Corn, field, starch 0.050000 1.000 1.000 1500123001 15 Corn, field, starch

- babyfood 0.050000 1.000 1.000 1500124000 15 Corn, field, syrup 0.050000 1.500 1.000 1500124001 15 Corn, field, syrup

- babyfood 0.050000 1.500 1.000 1500125000 15 Corn, field, oil 0.050000 1.000 1.000 1500125001 15 Corn, field, oil

- babyfood 0.050000 1.000 1.000 1500126000 15 Corn, pop 0. 050000 1.000 1.000 1500127000 15 Corn, sweet 0.050000 1.000 1.000 1500127001 15 Corn, sweet

- babyfood 0.050000 1.000 1.000 2003128000 20C Cottonseed, oil 0.050000 1.000 1.000 200312800 1 20C Cottonseed, oil

- babyfood 0.050000 1.000 1.000 1100129000 11 Crabapple 0.050000 1.000 1.000 1307130000 13G Cranberry 0.500000 1.000 1.000 1307130001 13G Cranberry

- babyfood 0.500000 1.000 1.000 1307131000 13G Cranberry, dried 0.500000 1.000 1.000 1307132000 13G Cranberry, juice 0.500000 1.100 1.000 1307132001 13G Cranberry, juice

- babyfood 0.500000 1.100 1. 000 0401133000 4A Cress, garden 0.400000 1.000 1.000 0401134000 4A Cress, upland 0.400000 1.000 1.000 0902135000 9B Cucumber 0.050000 1.000 1.000 1302136000 13B Currant 0.200000 1.000 1.000 1302137000 13B Currant, dried 0.200000 1.000 1.000 0401138000 4A Dandelion, leaves 0.400000 1.000 1.000 0103139000 1CD Dasheen, corm 0.10000 0 1.000 1.000 0200140000 2 Dasheen, leaves 0.100000 1.000 1.000 1902143000 19B Dill, seed 0.050000 1.000 1.000 0802148000 8BC Eggplant 0.050000 1.000 1.000 1302149000 13B Elderberry 0.200000 1.000 1.000 0401150000 4A Endive 0.400000 1.000 1.000 0402152000 4B Fennel, Florence 0.400000 1.000 1.000 1400155000 14 Hazelnut 0.200000 1.000 1.000 1400156000 14 Hazelnut, oil 0.200000 1.000 1.000 8000157000 80 Fish

- freshwater finfish 0.100000 1.000 1.000 8000158000 80 Fish

- freshwater finfish, farm ra 0.100000 1.000 1.000 8000159000 80 Fish

- saltwater finfish, tuna 0.100000 1.000 1.000 8000160000 80 Fish

- saltwater finfish, other 0.100000 1.000 1.000 8000161000 80 Fish

- shellfish, crustacean 1.000000 1.000 1.000 8000162000 80 Fish

- shellfish, mollusc 1.000000 1.000 1.000 0301165000 3A Garlic, bulb 0.050000 1.000 1.000 0301165001 3A Garlic, bulb

- babyfood 0.050000 1.000 1.000 0103166000 1CD Ginger 0.100000 1.000 1.000 0103166001 1CD Ginger

- babyfood 0.100000 1.000 1.000 0103167000 1CD Ginger, dried 0.100000 1.000 1.000 0101168000 1AB Ginseng, dried 0.100000 1.000 1.000 3200169000 32 Go at, meat 0.300000 1.000 1.000 3200170000 32 Goat, meat byproducts 4.000000 1.000 1.000 3200171000 32 Goat, fat 0.300000 1.000 1.000 3200172000 32 Goat, kidney 4.000000 1.000 1.000 3200173000 32 Goat, liver 0.300000 1.000 1.000 1302174000 13B Gooseberry 0.200000 1.000 1.000 1304175000 13D Grape 0.050000 1.000 1.000 13041 76000 13D Grape, juice 0.050000 1.000 1.000 1304176001 13D Grape, juice

- babyfood 0.050000 1.000 1.000 9500177000 O Grape, leaves 0.050000 1.000 1.000 9500178000 O Grape, raisin 0.050000 1.000 1.000 1304179000 13D Grape, wine and sherry 0.050000 1.000 1.000 1003180000 10C Grapefruit 3.000000 1.000 1.000 1003181000 10C Grapefruit, juice 3.000000 1.000 1.000 0603182000 6C Guar, seed 0.050000 1.000 1.000 0603182001 6C Guar, seed

- babyfood 0.050000 1.000 1.000 1400185000 14 Hickory nut 0.200000 1.000 1.000 0901187000 9A Honeydew melon 0.050000 1.000 1.000 9500188000 O Hop 0.200000 1.000 1.000 3300189000 33 Horse, meat 0.300000 1.000 1.000 0101190000 1AB Horseradish 0.100000 1.000 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 12 of 22 1302191000 13B Huckleberry 0.200000 1.000 1.000 0502194000 5B Kale 0.400000 1.000 1.000 0501196000 5A Kohlrabi 0.400000 1.000 1.000 1002197000 10B Kumquat 3.000000 1.000 1.000 0302198000 3B Leek 0.050000 1.000 1.000 1002199000 10B Lemon 3.000000 1.000 1.000 1002200000 10B Le mon, juice 3.000000 1.000 1.000 1002200001 10B Lemon, juice

- babyfood 3.000000 1.000 1.000 1002201000 10B Lemon, peel 3.000000 1.000 1.000 0603203000 6C Lentil, seed 0.050000 1.000 1.000 0401204000 4A Lettuce, head 0.400000 1.000 1.000 0401205000 4A Lettuce, leaf 0.400000 1.000 1.000 1002206000 10B Lime 3.000000 1.000 1.000 10022 07000 10B Lime, juice 3.000000 1.000 1.000 1002207001 10B Lime, juice

- babyfood 3.000000 1.000 1.000 1301208000 13A Loganberry 0.200000 1.000 1.000 1100210000 11 Loquat 0.050000 1.000 1.000 1400213000 14 Macadamia nut 0.200000 1.000 1.000 3600222000 36 Milk, fat 0.050000 1.000 1.000 3600222001 36 Milk, fat

- baby food/infant formu 0.050000 1.000 1.000 3600223000 36 Milk, nonfat solids 0.050000 1.000 1.000 3600223001 36 Milk, nonfat solids

- baby food/in 0.050000 1.000 1.000 3600224000 36 Milk, water 0.050000 1.000 1.000 3600224001 36 Milk, w ater

- babyfood/infant form 0.050000 1.000 1.000 3600225001 36 Milk, sugar (lactose)

- baby food/ 0.050000 1.000 1.000 1500226000 15 Millet, grain 2.000000 1.000 1.000 1303227000 13C Mulberry 0.200000 1.000 1.000 0502229000 5B Mustard greens 0.400000 1.000 1.000 1202230000 12B Nectarine 0.050000 1.000 1.000 1500231000 15 Oat, bran 2.00 0000 1.000 1.000 1500232000 15 Oat, flour 2.000000 1.000 1.000 1500232001 15 Oat, flour

- babyfood 2.000000 1.000 1.000 1500233000 15 Oat, groats/rolled oats 2.000000 1.000 1.000 1500233001 15 Oat, groats/rolled oats

- babyfood 2.000000 1.000 1.000 0802234000 8BC Okra 0.050000 1.000 1.000 0301237000 3A Onion, bulb 0.050000 1.000 1.000 0301237001 3A Onion, bulb

- babyfood 0.050000 1.000 1.000 0301238000 3A Onion, bulb, dried 0.050000 9.000 1.000 0301238001 3A Onion, bulb, dried

- babyfood 0.050000 9.000 1.000 0302239000 3B Onion, green 0.050000 1.000 1.00 0 1001240000 10A Orange 3.000000 1.000 1.000 1001241000 10A Orange, juice 3.000000 1.000 1.000 1001241001 10A Orange, juice

- babyfood 3.000000 1.000 1.000 1001242000 10A Orange, peel 3.000000 1.000 1.000 0401248000 4A Parsley, leaves 0.400000 1.000 1.000 0101250000 1AB Parsley, turnip rooted 0.100000 1.000 1.000 0101251000 1AB Parsnip 0.100000 1.000 1.000 0101251001 1AB Parsnip

- babyfood 0.100000 1.000 1.000 0602255000 6B Pea, succulent 0.050000 1.000 1.000 0602255001 6B Pea, succulent

- babyfood 0.050000 1.000 1.000 0603256000 6C Pea, dry 0.050000 1.000 1.000 0603256001 6C Pea, dry

- babyfood 0.050000 1.000 1.000 0601257000 6A Pea, edible podded, succulent 0.050000 1.000 1.000 0603258000 6C Pea, pigeon, seed 0.050000 1.000 1.000 0602259000 6B Pea, pigeon, succulent 0.050000 1.000 1.000 1202260000 12B Peach 0.050000 1.000 1.000 1202260001 12B Peach

- babyfood 0.050000 1.000 1.000 1202261000 12B Peach, dried 0.050000 7.000 1.000 1202261001 12B Peach, dried

- babyfood 0.050000 7.000 1.000 1202262000 12B Peach, juice 0.050000 1.500 1.000 1202262001 12B Peach, juice

- babyfood 0.050000 1.500 1.000 1100266000 11 Pear 0.050000 1.000 1.000 1100266001 11 Pear

- babyfood 0.050000 1.000 1.000 1100267000 11 Pe ar, dried 0.050000 6.250 1.000 1100268000 11 Pear, juice 0.050000 1.000 1.000 1100268001 11 Pear, juice

- babyfood 0.050000 1.000 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 13 of 22 1400269000 14 Pecan 0.200000 1.000 1.000 0802270000 8B Pepper, bell 0.050000 1.000 1.000 0802270001 8B Pepper, bell

- babyfood 0.050000 1.000 1.000 0802271000 8B Pepper, bell, dried 0.050000 1.000 1.000 08022 71001 8B Pepper, bell, dried

- babyfood 0.050000 1.000 1.000 0802272000 8BC Pepper, nonbell 0.050000 1.000 1.000 0802272001 8BC Pepper, nonbell

- babyfood 0.050000 1.000 1.000 0802273000 8BC Pepper, nonbell, dri ed 0.050000 1.000 1.000 1400278000 14 Pine nut 0.200000 1.000 1.000 1400282000 14 Pistachio 0.200000 1.000 1.000 1203285000 12C Plum 0.050000 1.000 1.000 1203285001 12C Plum

- babyfood 0.050000 1.000 1.000 1203286000 12C Plum, prune, fresh 0.050000 1.000 1.000 1203286001 12C Plum, prune, fresh

- babyfood 0.050000 1.000 1.000 1203287000 12C Plum, p rune, dried 0.050000 1.000 1.000 1203287001 12C Plum, prune, dried

- babyfood 0.050000 1.000 1.000 1203288000 12C Plum, prune, juice 0.050000 1.400 1.000 1203288001 12C Plum, prune, juice

- babyfood 0.050000 1.400 1.000 0103296000 1C Potato, chips 0.400000 3.600 1.000 0103297000 1C Potato, dry (granules/ flakes) 0.400000 3.700 1.000 0103297001 1C Potato, dry (granules/ flakes)

- b 0.400000 3.700 1.000 0103298000 1C Potato, flour 0.400000 3.700 1.000 0103298001 1C Potato, flour

- babyfood 0.400000 3.700 1.000 0103299000 1C Potato, tuber, w/peel 0.400000 1.000 1.000 0103299001 1C Potato, tuber, w/peel

- babyfood 0.400000 1.000 1.000 0103300000 1C Potato, tuber, w/o peel 0.400000 1.000 1.000 0103300001 1C Potato, tuber, w/o peel

- babyfood 0.400000 1.000 1.000 1003307000 10C Pummelo 3.000000 1.000 1.000 0902308000 9B Pumpkin 0.050000 1.000 1.000 0902309000 9B Pumpkin, seed 0.050000 1.000 1.000 1100310000 11 Quince 0.050000 1.000 1.000 0401313000 4A R adicchio 0.400000 1.000 1.000 0101314000 1AB Radish, roots 0.100000 1.000 1.000 0200315000 2 Radish, tops 0.100000 1.000 1.000 0101316000 1AB Radish, Oriental, roots 0.100000 1.000 1.000 0200317000 2 Radish, Oriental, tops 0.100000 1.000 1.000 0502318000 5B Rape greens 0.400000 1.000 1.000 1301320000 13A Raspberry 0.200000 1.000 1.000 1301 320001 13A Raspberry

- babyfood 0.200000 1.000 1.000 1301321000 13A Raspberry, juice 0.200000 1.000 1.000 1301321001 13A Raspberry, juice

- babyfood 0.200000 1.000 1.000 0402322000 4B Rhubarb 0.400000 1.000 1.000 1500323000 15 Rice, white 0.500000 1.000 1.000 1500323001 15 Rice, white

- babyfood 0.500000 1.000 1.000 1500324000 15 Rice, brown 0.500000 1.00 0 1.000 1500324001 15 Rice, brown

- babyfood 0.500000 1.000 1.000 1500325000 15 Rice, flour 0.500000 1.000 1.000 1500325001 15 Rice, flour

- babyfood 0.500000 1.000 1.000 1500326000 15 Rice, bran 0.500000 1.000 1.000 1500326001 15 Rice, bran

- babyfood 0.500000 1.000 1.000 0101327000 1AB Rutabaga 0.100000 1.000 1.000 1500328000 15 Rye, grain 2.000000 1.000 1.000 1500329000 15 Rye, flour 2.000000 1.000 1.000 0101331000 1AB Salsify, roots 0.100000 1.000 1.000 0200332000 2 Salsify, tops 0.100000 1.000 1.000 0302338500 3B Shallot, fresh leaves 0.050000 1.000 1.000 3500339000 35 Sheep, meat 0.300000 1.000 1.000 3500339001 35 Sheep, meat

- babyfood 0.300000 1.000 1.000 3500340000 35 Sh eep, meat byproducts 0.300000 1.000 1.000 3500341000 35 Sheep, fat 0.300000 1.000 1.000 3500341001 35 Sheep, fat

- babyfood 0.300000 1.000 1.000 3500342000 35 Sheep, kidney 4.000000 1.000 1.000 3500343000 35 Sheep, liver 0.300000 1.000 1.000 1500344000 15 Sorghum, grain 0.200000 1.000 1.000 1500345000 15 Sorghum, syrup 0.200000 1.000 1.000 06003 47000 6 Soybean, seed 0.050000 1.000 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 14 of 22 0603348000 6C Soybean, flour 0.050000 1.000 1.000 0603348001 6C Soybean, flour

- babyfood 0.050000 1.000 1.000 0600349000 6 Soybean, soy milk 0.050000 1.000 1.000 0600349001 6 Soybean, soy milk

- babyfood or in 0.050000 1.000 1.000 0600350000 6 Soybean, oil 0.050000 1.000 1.000 0600350001 6 Soybean, oil

- babyfood 0.050000 1.000 1.000 0401355000 4A Spinach 0.400000 1.000 1.000 0401355001 4A Spinach

- babyfood 0.400000 1.000 1.000 0902356000 9B Squash, summer 0.050000 1.000 1.000 0902356001 9B Squash, summer
- babyfood 0.050000 1.000 1.000 0902357000 9B Squash, winter 0.050000 1.000 1.000 0902357001 9B Squash, winter

- babyfood 0.050000 1.000 1.000 1307359000 13G Strawberry 0.0 50000 1.000 1.000 1307359001 13G Strawberry

- babyfood 0.050000 1.000 1.000 1307360000 13G Strawberry, juice 0.050000 1.000 1.000 1307360001 13G Strawberry, juice

- babyfood 0.050000 1.000 1.000 9500362000 O Sugarcane, sugar 0.050000 1.000 1.000 9500362001 O Sugarcane, sugar

- babyfood 0.050000 1.000 1.000 9500363000 O Sugarcane, molasses 0.200000 1.000 1.000 9500363001 O Sugarcane, molasses

- babyf ood 0.200000 1.000 1.000 0103366000 1CD Sweet potato 0.100000 1.000 1.000 0103366001 1CD Sweet potato

- babyfood 0.100000 1.000 1.000 0402367000 4B Swiss chard 0.400000 1.000 1.0 00 1001369000 10A Tangerine 3.000000 1.000 1.000 1001370000 10A Tangerine, juice 3.000000 1.000 1.000 0103371000 1CD Tanier, corm 0.100000 1.000 1.000 0801374000 8A Tomatillo 0.050000 1.000 1.000 0801375000 8A Tomato 0.050000 1.000 1.000 0801375001 8A Tomato

- babyfood 0.050000 1.000 1.000 0801376000 8A Tomato, paste 0.050000 1.000 1.000 0801376001 8A Tomato, paste

- babyfood 0.050000 1.000 1.000 0801377000 8A Tomato, puree 0.050000 1.000 1.000 0801377001 8A Tomato, puree

- babyfood 0.050000 1.000 1.000 0801378000 8A Tomato, dried 0.050000 14.300 1.000 0801378001 8A Tomato, dried

- babyfood 0.050000 14.300 1.000 0801379000 8A Tomato, juice 0.050000 1.500 1.000 0801380000 8A Tomato, Tree 0.050000 1.000 1.000 1500381000 15 Triticale, flour 0.050000 1.000 1.000 1500381001 15 Triticale, flour

- babyfood 0.050000 1.000 1.000 0103387000 1CD Turmeric 0.100000 1.000 1.000 0101388000 1AB Turnip, roots 0.100000 1.000 1.000 0502389000 5B Turnip, greens 0.400000 1.000 1.000 1400391000 14 Walnut 0.200000 1.000 1.000 8601000000 86A Water, direct, all sources 0.136000 1.000 1.000 8602000000 86B Water, indirect, all sources 0.136000 1.000 1.000 0901399000 9A Watermelon 0.050000 1.000 1.000 0901400000 9A Watermelon, juice 0.050000 1.000 1.000 1500401000 15 Wheat, grain 2.000000 1.000 1.000 1500401001 15 Wheat, grain

- babyfood 2.000000 1.000 1.000 1500402000 15 Wheat, flour 2.000000 1.000 1.000 1500402001 15 Wh eat, flour

- babyfood 2.000000 1.000 1.000 1500403000 15 Wheat, germ 2.000000 1.000 1.000 1500404000 15 Wheat, bran 4.000000 1.000 1.000 1500405000 15 Wild rice 0.050000 1.000 1.000 0103406000 1CD Yam, true 0.100000 1.000 1.000 0103407000 1CD Yam bean 0.100000 1.000 1.000 0301338000 3A Shallot, bulb 0.050000 1.000 1.000 06013 49500 6AB Soybean, vegetable 0.050000 1.000 1.000 1100173500 11 Goji berry 0.050000 1.000 1.000 9500373500 O Teff, flour 2.000000 1.000 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 15 of 22 

### Attachment 2 : DEEM

- FCID  

### Acute Exposure and Risk Estimates.

U.S. EPA Ver. 3.16, 03

- 08

- d
DEEM

- FCID ACUTE Analysis for 2,4

- D NHANES 2003

- 2008 2

- Day Residue file: 24D_ACUTE_SCREEN_TOLERANCE FOR ALL_061113.R08 Adjustment factor #2 NOT used. Analysis Date: 06

- 12

- 2013/14:38:27 Residue file dated: 06

- 12

- 2013/14:33:00 NOEL (Acute) = 67.000000 mg/kg body

- wt/day Acute Pop Adjusted Dose (aPAD) varies with population; see individual reports RAC/FF intake summed over 24 hours Run Comment: ""

===============================================================================

Summary calculations

-- per capita:

--- 95th Percentile

---- --- 99th Percentile

---- --- 99.9th Percentile

---- Exposure % aPAD MOE Ex posure % aPAD MOE Exposure % aPAD MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- -------- Total US Population: 0.032148 4.80 2084 0.062440 9.32 1073 0.147199 21.97 455 All Infants: 0.040035 5.98 1673 0.058087 8.67 1153 0.133057 19.86 503 Children 1

- 2: 0.095354 14.23 702 0.178882 26.70 374 0.278658 41.59 240 Children 3

- 5: 0.076901 11.48 871 0.128961 19.25 519 0.191934 28.65 349 Children 6

- 12: 0.044076 6.58 1520 0.076972 11.49 870 0.161557 24.11 414 Youth 13

- 19: 0.030884 4.61 2169 0.049710 7.42 1347 0.082652 12.34 810 Adults 20

- 49: 0.025527 3.8 1 2624 0.040147 5.99 1668 0.071440 10.66 937 Adults 50

- 99: 0.021844 3.26 3067 0.035784 5.34 1872 0.057036 8.51 1174 Female 13

- 49: 0.025715 10.29 2605 0.040576 16.23 1651 0.065925 26.37 10162,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 16 of 22 

### Attachment 3 : DEEM

- FCID  C hronic R esidue F ile

.

U.S. EPA Ver. 3.16, 03

- 08

- d
DEEM

- FCID Chronic analysis for 2,4

- D Residue file: C: \ Documents and Settings \ ALEMAY \ My Documents \ 24D GMO corn \ 2012 dietary
assessment \ November 2012 update new DEEM \ 24D_CHRONIC_SCREEN_TOLERANCE FOR ALL_061113.R08 Adjust. #2 NOT used
An alysis Date 06

- 12

- 2013 Residue file dated: 06

- 12

- 2013/14:34:41 Reference dose (RfD) = 0.21 mg/kg bw/day

---------------------------------------------------------------------------------- Food Crop Residu e Adj.Factors EPA Code Grp Food Name (ppm) #1 #2

---------- ---- ------------------------------- ---------- ------ ------ 1400003000 14 Almond 0.200000 1.000 1.000 1400003001 14 Almond

- babyfood 0.200000 1.000 1.000 1400004000 14 Almond, oil 0.200000 1.000 1.000 1400004001 14 Almond, oil

- babyfood 0.200000 1.000 1.000 0401005 000 4A Amaranth, leafy 0.400000 1.000 1.000 1100007000 11 Apple, fruit with peel 0.050000 1.000 1.000 1100008000 11 Apple, peeled fruit 0.050000 1.000 1.000 1100008001 11 A pple, peeled fruit

- babyfood 0.050000 1.000 1.000 1100009000 11 Apple, dried 0.050000 8.000 1.000 1100009001 11 Apple, dried

- babyfood 0.050000 8.000 1.000 1100010000 11 Apple, juice 0.050000 1.000 1.000 1100010001 11 Apple, juice

- babyfood 0.050000 1.000 1.000 1100011000 11 Apple, sauce 0.050000 1.000 1.000 1100011001 11 Apple, sauce

- babyfood 0.050000 1.000 1.000 1202012000 12B Apricot 0.050000 1.000 1.000 1202012001 12B Apricot

- babyfood 0.050000 1.000 1.000 1202013000 12B Apri cot, dried 0.050000 6.000 1.000 1202014000 12B Apricot, juice 0.050000 1.000 1.000 1202014001 12B Apricot, juice

- babyfood 0.050000 1.000 1.000 0103015000 1CD Arrowroot, flo ur 0.100000 1.000 1.000 0103015001 1CD Arrowroot, flour

- babyfood 0.100000 1.000 1.000 0103017000 1CD Artichoke, Jerusalem 0.100000 1.000 1.000 0401018000 4A Arugula 0.400000 1.000 1.000 9500019000 O Asparagus 5.000000 1.000 1.000 9500020000 O Avocado 0.050000 1.000 1.000 0902021000 9B Balsam pear 0.050000 1.000 1.000 1500025000 15 Barley, pearled barley 2.000000 1.000 1.000 1500025001 15 Barley, pearled barley

- babyfood 2.000000 1.000 1.000 1500026000 15 Barley, flour 2.000000 1.000 1.000 1500026001 15 Barley, flour

- babyfood 2.000000 1.000 1.000 1500027000 15 Barley, bran 4.000000 1.000 1.000 0603030000 6C Bean, black, seed 0.050000 1.000 1.000 0602031000 6B Bean, broad, succulent 0.050000 1.000 1.000 0603032000 6C Bean, broad, seed 0.050000 1.000 1.000 0602033000 6B Bean, cowpea, succulent 0.050000 1.000 1.000 0603034000 6C Bean, cowpea, seed 0.050000 1.000 1.000 0603035000 6C Bean, great northern, seed 0.050000 1.000 1.000 0603036000 6C Bean, kidney, seed 0.050000 1.000 1.000 06020370 00 6B Bean, lima, succulent 0.050000 1.000 1.000 0603038000 6C Bean, lima, seed 0.050000 1.000 1.000 0603039000 6C Bean, mung, seed 0.050000 1.000 1.000 0603040000 6C Bean, navy, seed 0.050000 1.000 1.000 0603041000 6C Bean, pink, seed 0.050000 1.000 1.000 0603042000 6C Bean, pinto, seed 0.050000 1.000 1.000 0601043000 6A Bean, snap, succulent 0.050000 1.000 1.000 0601043001 6A Bean, snap, succulent

- babyfood 0.050000 1.000 1.000 3100044000 31 Beef, meat 0.300000 1.000 1.000 3100044001 31 Beef , meat

- babyfood 0.300000 1.000 1.000 3100045000 31 Beef, meat, dried 0.300000 1.920 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 17 of 22 3100046000 31 Beef, meat byproducts 4.000000 1.000 1.000 3100046001 31 Beef, meat byp roducts

- babyfood 4.000000 1.000 1.000 3100047000 31 Beef, fat 0.300000 1.000 1.000 3100047001 31 Beef, fat

- babyfood 0.300000 1.000 1.000 3100048000 31 Beef, kidney 4.000000 1.000 1.000 3100049000 31 Beef, liver 0.300000 1.000 1.000 3100049001 31 Beef, liver

- babyfood 0.300000 1.000 1.000 0101050000 1AB Beet, garden, roots 0.100000 1.000 1.000 0101050001 1AB Beet, garden, roots

- babyfood 0.100000 1.000 1.000 0200051000 2 Beet, garden, tops 0.100000 1.000 1.000 0101052000 1A Beet, sugar 0.100000 1.000 1.000 0101052001 1A Beet, sugar

- babyfood 0.100000 1.000 1.000 0101053000 1A Beet, sugar, molasses 0.100000 1.000 1.000 0101053001 1A Beet, sugar, molasses

- babyfood 0.100000 1.000 1.000 1301055000 13A Blackberry 0.200000 1.000 1.000 1301056000 13A Blackberry, juice 0.200000 1.000 1.000 1301056001 13A Blackberry, juice

- babyfood 0.200000 1.000 1.000 1302057000 13B Blueberry 0.200000 1.000 1.000 1302057001 13B Blueberry

- babyfood 0.200000 1.000 1.000 1301058000 13A Boysenberry 0.200000 1.000 1.000 1400059000 14 Brazil nut 0.200000 1.000 1.000 0501061000 5A Broccoli 0.400000 1.000 1.000 0501061001 5A Broccoli

- babyfood 0.400000 1.000 1.000 0501062000 5A Broccoli, Chinese 0.400000 1.000 1.000 0502063000 5B Broccoli raab 0.400000 1.000 1.000 0501064000 5A Brussels sprouts 0.400000 1.000 1.000 0101067000 1AB Burd ock 0.100000 1.000 1.000 1400068000 14 Butternut 0.200000 1.000 1.000 0501069000 5A Cabbage 0.400000 1.000 1.000 0502070000 5B Cabbage, Chine se, bok choy 0.400000 1.000 1.000 0501071000 5A Cabbage, Chinese, napa 0.400000 1.000 1.000 0501072000 5A Cabbage, Chinese, mustard 0.400000 1.000 1.000 0901075000 9A Cantaloupe 0.050000 1.000 1.000 0402076000 4B Cardoon 0.400000 1.000 1.000 0101078000 1AB Carrot 0.100000 1.000 1.000 0101078001 1AB Carrot

- babyfood 0.100000 1.000 1.000 0101079000 1AB Carrot, juice 0.100000 1.000 1.000 1400081000 14 Cashew 0.200000 1.000 1.000 0103082000 1CD Cassava 0.100000 1.000 1.000 0103082001 1CD Cassava

- babyfood 0.100000 1.000 1.000 0501083000 5A Cauliflower 0.400000 1.000 1.000 0101084000 1AB Celeriac 0.100000 1.000 1.000 0402085000 4B Celery 0.400000 1.000 1.000 0402085001 4B Celery

- babyfood 0.400000 1.000 1.000 0402086000 4B Celery, juice 0.400000 1.000 1.000 0402087000 4B Celtuce 0.400000 1.000 1.000 0902088000 9B Chayote, fruit 0.050000 1.000 1.000 1201090000 12A Cherry 0.050000 1.000 1.000 1201090001 12A Cherry

- babyfood 0.050000 1.000 1.000 1201091000 12A Cherry, juice 0.050000 1.500 1.000 1201091001 12A Cherry, juice

- babyfood 0.050000 1.500 1.000 1400092000 14 Chestnut 0.200000 1.000 1.000 0603098000 6C Chickpea, seed 0.050000 1.000 1.000 0603098001 6C Chickpea, seed

- babyfood 0.050000 1.000 1.000 0603099000 6C Chic kpea, flour 0.050000 1.000 1.000 0101100000 1AB Chicory, roots 0.100000 1.000 1.000 0200101000 2 Chicory, tops 0.100000 1.000 1.000 0902102000 9B Chinese waxgou rd 0.050000 1.000 1.000 0302103000 3B Chive, fresh leaves 0.050000 1.000 1.000 0401104000 4A Chrysanthemum, garland 0.400000 1.000 1.000 1001106000 10A Citron 3.000000 1.000 1.000 1001107000 10A Citrus hybrids 3.000000 1.000 1.000 1001108000 10A Citrus, oil 3.000000 1.000 1.000 0502117000 5B Collards 0.400000 1.000 1.000 1500120000 15 Corn, field, flour 0.050000 1.000 1.000 1500120001 15 Corn, field, flour

- babyfood 0.050000 1.000 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 18 of 22 1500121000 15 Corn, field, meal 0.050000 1.000 1.000 1500121001 15 Corn, field, meal

- babyfood 0.050000 1.000 1.000 1500122000 15 Corn, field, bran 0.050000 1.000 1.000 1500123000 15 Corn, field, starch 0.050000 1.000 1.000 1500123001 15 Corn, field, starch

- babyfood 0.050000 1.000 1.000 1500124000 15 Corn, field, syrup 0.050000 1.500 1.000 1500124001 15 Corn, field, syrup

- babyfood 0.050000 1.500 1.000 1500125000 15 Corn, field, oil 0.050000 1.000 1.000 1500125001 15 Corn, field, oil

- babyfood 0.050000 1.000 1.000 1500126000 15 Corn, pop 0.050000 1.000 1.000 15001270 00 15 Corn, sweet 0.050000 1.000 1.000 1500127001 15 Corn, sweet

- babyfood 0.050000 1.000 1.000 2003128000 20C Cottonseed, oil 0.050000 1.000 1.000 2003128001 20C Cottonseed, oil

- babyfood 0.050000 1.000 1.000 1100129000 11 Crabapple 0.050000 1.000 1.000 1307130000 13G Cranberry 0.500000 1.000 1.000 1307130001 13G Cranberry

- babyfood 0.500000 1.000 1.000 1307131000 13G Cranberry, dried 0.500000 1.000 1.000 1307132000 13G Cranberry, juice 0.500000 1.100 1.000 1307132001 13G Cranberry, juice

- bab yfood 0.500000 1.100 1.000 0401133000 4A Cress, garden 0.400000 1.000 1.000 0401134000 4A Cress, upland 0.400000 1.000 1.000 0902135000 9B Cucumber 0.050000 1.000 1.000 1302136000 13B Currant 0.200000 1.000 1.000 1302137000 13B Currant, dried 0.200000 1.000 1.000 0401138000 4A Dandelion, leaves 0.400 000 1.000 1.000 0103139000 1CD Dasheen, corm 0.100000 1.000 1.000 0200140000 2 Dasheen, leaves 0.100000 1.000 1.000 1902143000 19B Dill, seed 0.050000 1.00 0 1.000 0802148000 8BC Eggplant 0.050000 1.000 1.000 1302149000 13B Elderberry 0.200000 1.000 1.000 0401150000 4A Endive 0.400000 1.000 1.0 00 0402152000 4B Fennel, Florence 0.400000 1.000 1.000 1400155000 14 Hazelnut 0.200000 1.000 1.000 1400156000 14 Hazelnut, oil 0.200000 1.000 1.000 8000 157000 80 Fish

- freshwater finfish 0.100000 1.000 1.000 8000158000 80 Fish

- freshwater finfish, farm ra 0.100000 1.000 1.000 8000159000 80 Fish

- saltwater finfish, tuna 0.100000 1.000 1.000 8000160000 80 Fish

- saltwater finfish, other 0.100000 1.000 1.000 8000161000 80 Fish

- shellfish, crustacean 1.000000 1.000 1.000 8000162000 80 Fish

- shellfish, mollusc 1.000000 1.000 1.000 0301165000 3A Garlic, bulb 0.050000 1.000 1.000 0301165001 3A Garlic, bulb

- babyfood 0.050000 1.000 1.000 0103166000 1CD Ginger 0.100000 1.000 1.000 0103166001 1CD Ginger

- babyfood 0.100000 1.000 1.000 0103167000 1CD Ginger, dried 0.100000 1.000 1.000 0101168000 1AB Ginseng, dried 0.100000 1.000 1.000 3200169000 32 Goat , meat 0.300000 1.000 1.000 3200170000 32 Goat, meat byproducts 4.000000 1.000 1.000 3200171000 32 Goat, fat 0.300000 1.000 1.000 3200172000 32 Goat, kidney 4.000000 1.000 1.000 3200173000 32 Goat, liver 0.300000 1.000 1.000 1302174000 13B Gooseberry 0.200000 1.000 1.000 1304175000 13D Grape 0.050000 1.000 1.000 1304176000 13D Grape, juice 0.050000 1.000 1.000 1304176001 13D Grape, juice

- babyfood 0.050000 1.000 1.000 9500177000 O Grape, leaves 0.050000 1.000 1.000 9500178000 O Grape, raisin 0.050000 1.000 1.000 1304179000 13D Grape, wine and sherry 0.050000 1.000 1.000 1003180000 10C Grapefruit 3.000000 1.000 1.000 1003181000 10C Grapefruit, juice 3.000000 1.000 1.000 0603182000 6C Guar, seed 0.050000 1.000 1.000 0603182001 6C Guar, seed

- babyfood 0.050000 1.000 1.000 1400185000 14 Hickory nut 0.200000 1.000 1.000 0901187000 9A Honeydew melon 0.050000 1.000 1.000 9500188000 O Hop 0.200000 1.000 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 19 of 22 3300189000 33 Horse, meat 0.300000 1.000 1.000 0101190000 1AB Horseradish 0.100000 1.000 1.000 1302191000 13B Huckleberry 0.200000 1.000 1.000 0502194000 5B Kale 0.400000 1.000 1.000 0501196000 5A Kohlrabi 0.400000 1.000 1.000 1002197000 10B Kumquat 3.000000 1.000 1.000 0302198000 3B Leek 0.050000 1.000 1.000 1002199000 10B Lemon 3.000000 1.000 1.000 1002200000 10B Lemon, juice 3.000000 1.000 1.000 1002200001 10B Lemo n, juice

- babyfood 3.000000 1.000 1.000 1002201000 10B Lemon, peel 3.000000 1.000 1.000 0603203000 6C Lentil, seed 0.050000 1.000 1.000 0401204000 4A Lettuce, head 0.400000 1.000 1.000 0401205000 4A Lettuce, leaf 0.400000 1.000 1.000 1002206000 10B Lime 3.000000 1.000 1.000 1002207000 10B Lime, juice 3.000000 1.000 1.000 1002207001 10B Lime, juice

- babyfood 3.000000 1.000 1.000 1301208000 13A Loganberry 0.200000 1.000 1.000 1100210000 11 Loquat 0.050000 1.000 1.000 1400213000 14 Macadamia nut 0.200000 1.000 1.000 3600222000 36 Milk, fat 0.050000 1.000 1.000 3600222001 36 Milk, fat

- baby food/infant formu 0.050000 1.000 1.000 3600223000 36 Milk, nonfat solids 0.050000 1.000 1.000 3600223001 36 Milk, nonfat solids

- baby food/in 0.050000 1.000 1.000 3600224000 36 Milk, water 0.050000 1.000 1.000 3600224001 36 Milk, water

- babyfood/infant form 0.050000 1.000 1.000 3600225001 36 Milk, sugar (lactose)

- baby food/ 0.050000 1.000 1.000 1500226000 15 Millet, grain 2.000000 1.000 1.000 1303227000 13C Mulberry 0.200000 1.000 1.000 0502229000 5B Mustard greens 0.400000 1.000 1.000 1202230000 12B Nectarine 0.050000 1.000 1.000 15002310 00 15 Oat, bran 2.000000 1.000 1.000 1500232000 15 Oat, flour 2.000000 1.000 1.000 1500232001 15 Oat, flour

- babyfood 2.000000 1.000 1.000 1500233000 15 Oat, groats/rolled oats 2.000000 1.000 1.000 1500233001 15 Oat, groats/rolled oats

- babyfood 2.000000 1.000 1.000 0802234000 8BC Okra 0.050000 1.000 1.000 0301237000 3A Onion, bulb 0.050000 1.000 1.000 0301237001 3A Onion, bulb

- babyfood 0.050000 1.000 1.000 0301238000 3A Onion, bulb, dried 0.050000 9.000 1.000 0301238001 3A Onio n, bulb, dried

- babyfood 0.050000 9.000 1.000 0302239000 3B Onion, green 0.050000 1.000 1.000 1001240000 10A Orange 3.000000 1.000 1.000 1001241000 10A Orange, juice 3.000000 1.000 1.000 1001241001 10A Orange, juice

- babyfood 3.000000 1.000 1.000 1001242000 10A Orange, peel 3.000000 1.000 1.000 0401248000 4A Parsley, leaves 0.400000 1.000 1.000 0101250000 1AB Parsley, turnip rooted 0.100000 1.000 1.000 0101251000 1AB Parsnip 0.100000 1.000 1.000 0101251001 1AB Parsnip

- babyfood 0.100000 1.000 1.000 0602255000 6B Pea, succulent 0.050000 1.000 1.000 0602255001 6B Pea, succulent

- babyfood 0.050000 1.000 1.000 0603256000 6C Pea, dry 0.050000 1.000 1.000 0603256001 6C Pea, dry

- babyfood 0.050000 1.000 1.000 0601257000 6A Pea, edible podded, succulent 0.050000 1.000 1.000 0603258000 6C Pea, pigeon, seed 0.050000 1.000 1.000 0602259000 6B Pea, pigeon, succulent 0.050000 1.000 1.000 1202260000 12B Peach 0.050000 1.000 1.000 1202260001 12B Peach

- babyfood 0.050000 1.000 1.000 1202261000 12B Peach, dried 0.050000 7.000 1.000 1202261001 12B Peach, dried

- babyfood 0.050000 7.000 1.000 1202262000 12B Peach, juice 0.050000 1.500 1.000 1202262001 12B Peach, juice

- babyfood 0.050000 1.500 1.000 1100266000 11 Pear 0.050000 1.000 1.000 1100266001 11 Pear

- babyfood 0.050000 1.000 1.000 1100267000 11 Pear, dried 0.050000 6.250 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 20 of 22 1100268000 11 Pear, juice 0.050000 1.000 1.000 1100268001 11 Pear, juice

- babyfood 0.050000 1.000 1.000 1400269000 14 Peca n 0.200000 1.000 1.000 0802270000 8B Pepper, bell 0.050000 1.000 1.000 0802270001 8B Pepper, bell

- babyfood 0.050000 1.000 1.000 0802271000 8B Pepper, bell, dried 0.050000 1.000 1.000 0802271001 8B Pepper, bell, dried

- babyfood 0.050000 1.000 1.000 0802272000 8BC Pepper, nonbell 0.050000 1.000 1.000 0802272001 8BC Pepper, nonbell

- babyfood 0.050000 1.000 1.000 0802273000 8BC Pepper, nonbell, dried 0.050000 1.000 1.000 1400278000 14 Pine nut 0.200000 1.000 1.000 1400282000 14 Pistachio 0.200000 1.000 1.000 1203285000 12C Plum 0.050000 1.000 1.000 1203285001 12C Plum

- babyfood 0.050000 1.000 1.000 1203286000 12C Plum, prune, fresh 0.050000 1.000 1.000 1203286001 12C Plum, prune, fresh

- babyfood 0.050000 1.000 1.000 1203287000 12C Plum, prune, dried 0.050000 1.000 1.000 1203287001 12C Plum, prune, dried

- babyfood 0.050000 1.000 1.000 1203288000 12C Plum, prune, juice 0.050000 1.400 1.000 1203288001 12C Plum, prune, juice

- babyfood 0.050000 1.400 1.000 0103296000 1C Potato, chips 0.400000 3.600 1.000 0103297000 1C Potato, dry (granules/ flakes) 0.400000 3.700 1.000 0103297001 1C Potato, dry (granules/ flakes)

- b 0.400000 3.700 1.000 0103298000 1C Potato, flour 0.400000 3.700 1.000 0103298001 1C Potato, flour

- babyfood 0.400000 3.700 1.000 0103299000 1C Potato, tuber, w/peel 0.400000 1.000 1.000 0103299001 1C Potato, tuber, w/peel

- babyfood 0.400000 1.000 1.000 0103300000 1C Potato, tuber, w/o peel 0.400000 1.000 1.000 0103300001 1C Potato, tuber, w/o peel

- babyfood 0.400000 1.000 1.000 1003307000 10C Pummelo 3.000000 1.000 1.000 0902308000 9B Pump kin 0.050000 1.000 1.000 0902309000 9B Pumpkin, seed 0.050000 1.000 1.000 1100310000 11 Quince 0.050000 1.000 1.000 0401313000 4A Radicchio 0.400000 1.000 1.000 0101314000 1AB Radish, roots 0.100000 1.000 1.000 0200315000 2 Radish, tops 0.100000 1.000 1.000 0101316000 1AB Radish, Oriental, roots 0.100000 1.000 1.000 0200317000 2 Radish, Oriental, tops 0.100000 1.000 1.000 0502318000 5B Rape greens 0.400000 1.000 1.000 1301320000 13A Raspberry 0.200000 1.000 1.000 1301320001 13A Raspberry

- babyfood 0.200000 1.000 1.000 1301321000 13A Raspberry, juice 0.200000 1.000 1.000 1301321001 13A Raspberry, juice

- babyfood 0.200000 1.000 1.000 0402322000 4B Rhubarb 0.400000 1.000 1.000 1500323000 15 Rice, white 0.500000 1.000 1.000 1500323001 15 Rice, white

- babyfood 0.500000 1.000 1.000 1500324000 15 Rice, brown 0.500000 1.000 1.000 1500324001 15 Rice, brown

- babyfood 0.500000 1.000 1.000 1500325000 15 Rice, flour 0.500000 1.000 1.000 1500325001 15 Rice, flour

- babyfood 0.500000 1.000 1.000 1500326000 15 Rice, bran 0.500000 1.000 1.000 1500326001 15 Rice, bran

- babyfood 0.500000 1.000 1.000 01013270 00 1AB Rutabaga 0.100000 1.000 1.000 1500328000 15 Rye, grain 2.000000 1.000 1.000 1500329000 15 Rye, flour 2.000000 1.000 1.000 0101331000 1AB Salsify, roots 0.100000 1.000 1.000 0200332000 2 Salsify, tops 0.100000 1.000 1.000 0302338500 3B Shallot, fresh leaves 0.050000 1.000 1.000 3500339000 35 Sheep, mea t 0.300000 1.000 1.000 3500339001 35 Sheep, meat

- babyfood 0.300000 1.000 1.000 3500340000 35 Sheep, meat byproducts 0.300000 1.000 1.000 3500341000 35 Sheep, fat 0.300000 1.000 1.000 3500341001 35 Sheep, fat

- babyfood 0.300000 1.000 1.000 3500342000 35 Sheep, kidney 4.000000 1.000 1.000 3500343000 35 Sheep, liver 0.300000 1.000 1.000 1500344000 15 Sorghum, grain 0.200000 1.000 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 21 of 22 1500345000 15 Sorghum, syrup 0.200000 1.000 1.000 0600347000 6 Soybean, seed 0.050 000 1.000 1.000 0603348000 6C Soybean, flour 0.050000 1.000 1.000 0603348001 6C Soybean, flour

- babyfood 0.050000 1.000 1.000 0600349000 6 Soybean, soy milk 0.050000 1.00 0 1.000 0600349001 6 Soybean, soy milk

- babyfood or in 0.050000 1.000 1.000 0600350000 6 Soybean, oil 0.050000 1.000 1.000 0600350001 6 Soybean, oil

- babyfood 0.050000 1.000 1.0 00 0401355000 4A Spinach 0.400000 1.000 1.000 0401355001 4A Spinach

- babyfood 0.400000 1.000 1.000 0902356000 9B Squash, summer 0.050000 1.000 1.000 0902 356001 9B Squash, summer

- babyfood 0.050000 1.000 1.000 0902357000 9B Squash, winter 0.050000 1.000 1.000 0902357001 9B Squash, winter

- babyfood 0.050000 1.000 1.000 1307359000 13G Strawberry 0.050000 1.000 1.000 1307359001 13G Strawberry

- babyfood 0.050000 1.000 1.000 1307360000 13G Strawberry, juice 0.050000 1.000 1.000 1307360001 13G Strawberry, juice

- babyfood 0.050000 1.000 1.000 9500362000 O Sugarcane, sugar 0.050000 1.000 1.000 9500362001 O Sugarcane, sugar

- babyfood 0.050000 1.000 1.000 9500363000 O Sugarcane, molasses 0.200000 1.000 1.000 9500363001 O Sugarcane, molasses

- babyfood 0.200000 1.000 1.000 0103366000 1CD Sweet potato 0.100000 1.000 1.000 0103366001 1CD Sweet potato

- babyfoo d 0.100000 1.000 1.000 0402367000 4B Swiss chard 0.400000 1.000 1.000 1001369000 10A Tangerine 3.000000 1.000 1.000 1001370000 10A Tangerine, juice 3.000000 1.000 1.000 0103371000 1CD Tanier, corm 0.100000 1.000 1.000 0801374000 8A Tomatillo 0.050000 1.000 1.000 0801375000 8A Tomato 0.050 000 1.000 1.000 0801375001 8A Tomato

- babyfood 0.050000 1.000 1.000 0801376000 8A Tomato, paste 0.050000 1.000 1.000 0801376001 8A Tomato, paste

- babyfood 0.050000 1.00 0 1.000 0801377000 8A Tomato, puree 0.050000 1.000 1.000 0801377001 8A Tomato, puree

- babyfood 0.050000 1.000 1.000 0801378000 8A Tomato, dried 0.050000 14.300 1.0 00 0801378001 8A Tomato, dried

- babyfood 0.050000 14.300 1.000 0801379000 8A Tomato, juice 0.050000 1.500 1.000 0801380000 8A Tomato, Tree 0.050000 1.000 1.000 1500 381000 15 Triticale, flour 0.050000 1.000 1.000 1500381001 15 Triticale, flour

- babyfood 0.050000 1.000 1.000 0103387000 1CD Turmeric 0.100000 1.000 1.000 0101388000 1AB Turnip, roots 0.100000 1.000 1.000 0502389000 5B Turnip, greens 0.400000 1.000 1.000 1400391000 14 Walnut 0.200000 1.000 1.000 8601000000 86A Water , direct, all sources 0.023000 1.000 1.000 8602000000 86B Water, indirect, all sources 0.023000 1.000 1.000 0901399000 9A Watermelon 0.050000 1.000 1.000 0901400000 9A Watermelon, jui ce 0.050000 1.000 1.000 1500401000 15 Wheat, grain 2.000000 1.000 1.000 1500401001 15 Wheat, grain

- babyfood 2.000000 1.000 1.000 1500402000 15 Wheat, flour 2.000000 1.000 1.000 1500402001 15 Wheat, flour

- babyfood 2.000000 1.000 1.000 1500403000 15 Wheat, germ 2.000000 1.000 1.000 1500404000 15 Wheat, bran 4.000000 1.000 1.000 1500405000 15 Wild rice 0.050000 1.000 1.000 0103406000 1CD Yam, true 0.100000 1.000 1.000 0103407000 1CD Yam bean 0.100000 1.000 1.000 0301338000 3A Shallot, bulb 0.050000 1.000 1.000 0601349500 6AB Soybean, vegetable 0.050000 1.000 1.000 1100173500 11 Goji berry 0.050000 1.000 1.000 9500373500 O Teff, flour 2.000000 1.000 1.0002,4

- D Dietary Exposure and Risk Assessment DP #: D413003

_______________________________________________________________________________________ ______

Page 22 of 22 

### Attachment 4 : DEEM

- FCID  

### C hronic E xposure and Risk E stimates

.

U.S. EPA Ver. 3.16, 03

- 08

- d
DEEM

- FCID Chronic analysis for 2,4

- D NHANES 2003

- 2008 2

- day Residue file name: C: \ Documents and Settings \ ALEMAY \ My Documents \ 24D GMO corn \ 2012 dietary assessment \ November 2012 update new DEEM \ 24D_CHRONIC_SCREEN_TOLERANCE FOR ALL_061113.R08 Adjustment factor #2 NOT used. Analysis Date 06

- 12

- 2013/14:42:35 Residue file dated: 06

- 12

- 2013/14:34:41 Reference dose (RfD, Chronic) = .21 mg/kg bw/day

================================================= ============================== Total exposure by population subgroup

-------------------------------------------------------------------------------

Total Exposure

----------------------------------- Population mg/kg Percent of Subgroup body wt/day Rfd

-------------------------------------- --- ---------- ---------------- Total US Population 0.009879 4.7% Hispanic 0.012083 5.8%
Non

- Hisp

- White 0.009270 4.4%
Non

- Hisp

- Black 0.010490 5.0%
Non

- Hisp

- Other 0.010834 5.2% Nursing Infants 0.005120 2.4%
Non

- Nursing Infants 0.010457 5.0% Female 13+ PREG 0.010295 4.9% Children 1

- 6 0.026815 12.8% Children 7

- 12 0.013977 6.7% Male 13

- 19 0.010004 4.8% Female 13

- 19/NP 0.008239 3.9% Male 20+ 0.008043 3.8% Female 20+/NP 0.007118 3.4% Seniors 55+ 0.007202 3.4% All Infants 0.008809 4.2% Female 13

- 50 0.007477 3.6% Children 1

- 2 0.030720 14.6% Children 3

- 5 0.025914 12.3% Children 6

- 12 0.015031 7.2% Youth 13

- 19 0.009103 4.3% Adults 20

- 49 0.007845 3.7% Adults 50

- 99 0.007286 3.5% Female 13

- 49 0.007449 3.5%

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