111TH CONGRESS 

2D SESSION H. R. 1230 

AN ACT 

To amend the Public Health Service Act to provide for 

research on acquired bone marrow failure diseases, minority-focused programs on such diseases, and the development of best practices for diagnosis of and care for 

individuals with such diseases. 

1 Be it enacted by the Senate and House of Representa2 tives of the United States of America in Congress assembled, 
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1 SECTION 1. SHORT TITLE. 

2 This Act may be cited as the ‘‘Acquired Bone Marrow 

3 Failure Disease Research and Treatment Act of 2010’’. 

4 SEC. 2. ACQUIRED BONE MARROW FAILURE DISEASE RE5 SEARCH. 

6 Part B of title III of the Public Health Service Act 

7 (42 U.S.C. 243 et seq.) is amended by inserting after sec8 tion 317T the following: 

9 ‘‘SEC. 317U. ACQUIRED BONE MARROW FAILURE DISEASE 

10 RESEARCH. 

11 ‘‘(a) IN GENERAL.—The Secretary may conduct re12 search on acquired bone marrow failure diseases. Such re13 search may address factors including— 

14 ‘‘(1) trends in the characteristics of individuals 

15 who are diagnosed with acquired bone marrow fail16 ure diseases, including age, race and ethnicity, gen17 eral geographic location, sex, family history, and any 

18 other characteristics determined appropriate by the 

19 Secretary; 

20 ‘‘(2) the genetic and environmental factors, in21 cluding exposure to toxins, that may be associated 

22 with developing acquired bone marrow failure dis23 eases; 

24 ‘‘(3) approaches to treating acquired bone mar25 row failure diseases; 
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1 ‘‘(4) outcomes for individuals treated for ac2 quired bone marrow failure diseases, including out3 comes for recipients of stem cell therapeutic prod4 ucts; and 

5 ‘‘(5) any other factors pertaining to acquired 

6 bone marrow failure diseases determined appropriate 

7 by the Secretary. 

8 ‘‘(b) COLLABORATION WITH THE RADIATION INJURY

9 TREATMENT NETWORK.—In carrying out subsection (a), 

10 the Secretary may collaborate with the Radiation Injury 

11 Treatment Network of the C.W. Bill Young Cell Trans12 plantation Program established pursuant to section 379 

13 to— 

14 ‘‘(1) augment data for the studies under such 

15 subsection; 

16 ‘‘(2) access technical assistance that may be 

17 provided by the Radiation Injury Treatment Net18 work; or 

19 ‘‘(3) perform joint research projects. 

20 ‘‘(c) DEFINITION.—In this section, the term ‘ac21 quired bone marrow failure disease’ means— 

22 ‘‘(1) myelodysplastic syndromes (MDS); 

23 ‘‘(2) aplastic anemia; 

24 ‘‘(3) paroxysmal nocturnal hemoglobinuria 

25 (PNH); 
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1 ‘‘(4) pure red cell aplasia; 

2 ‘‘(5) acute myeloid leukemia that has pro3 gressed from myelodysplastic syndromes; 

4 ‘‘(6) large granular lymphocytic leukemia; or 

5 ‘‘(7) any other bone marrow failure disease 

6 specified by the Secretary, to the extent such disease 

7 is acquired and not inherited, as determined by the 

8 Secretary.’’. 

9 SEC. 3. MINORITY-FOCUSED PROGRAMS ON ACQUIRED 

10 BONE MARROW FAILURE DISEASES. 

11 Title XVII of the Public Health Service Act (42 

12 U.S.C. 300u et seq.) is amended by inserting after section 

13 1707A the following: 

14 ‘‘SEC. 1707B. MINORITY-FOCUSED PROGRAMS ON AC15 QUIRED BONE MARROW FAILURE DISEASES. 

16 ‘‘(a) INFORMATION AND REFERRAL SERVICES.— 

17 ‘‘(1) IN GENERAL.—The Secretary may estab18 lish and coordinate outreach and informational pro19 grams targeted to minority populations, including 

20 Hispanic, Asian-American, Native Hawaiian, and 

21 Pacific Islander populations, that are affected by ac22 quired bone marrow failure diseases. 

23 ‘‘(2) PROGRAM ACTIVITIES.—Programs under 

24 subsection (a) may carry out activities that in25 clude— 
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1 ‘‘(A) making information about treatment 

2 options and clinical trials for acquired bone 

3 marrow failure diseases publicly available; and 

4 ‘‘(B) providing referral services for treat5 ment options and clinical trials. 

6 ‘‘(b) DEFINITION.—In this section, the term ‘ac7 quired bone marrow failure disease’ has the meaning given 

8 such term in section 317U(c).’’. 

9 SEC. 4. BEST PRACTICES FOR DIAGNOSIS OF AND CARE 

10 FOR INDIVIDUALS WITH ACQUIRED BONE 

11 MARROW FAILURE DISEASES. 

12 Part B of title III of the Public Health Service Act 

13 (42 U.S.C. 243 et seq.), as amended by section 2, is fur14 ther amended by inserting after section 317U the fol15 lowing: 

16 ‘‘SEC. 317V. BEST PRACTICES FOR DIAGNOSIS OF AND CARE 

17 FOR INDIVIDUALS WITH ACQUIRED BONE 

18 MARROW FAILURE DISEASES. 

19 ‘‘(a) GRANTS.—The Secretary, acting through the 

20 Director of the Agency for Healthcare Research and Qual21 ity, may award grants to researchers to study best prac22 tices with respect to diagnosing acquired bone marrow 

23 failure diseases and providing care to individuals with such 

24 diseases. 
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1 ‘‘(b) DEFINITION.—In this section, the term ‘ac2 quired bone marrow failure disease’ has the meaning given 

3 such term in section 317U(c).’’. 

Passed the House of Representatives September 30 

(legislative day September 29), 2010. 

Attest: 

Clerk. 

111TH CONGRESS 

2D SESSION H. R. 1230 

AN ACT 

To amend the Public Health Service Act to provide 

diseases. diagnosis of and care for individuals with such eases, and the development of best practices for eases, minority-focused programs on such disfor research on acquired bone marrow failure dis-