Exhibit 12.1

Cephalon, Inc.  Computation of Ratio of Earnings to Fixed Charges  (Amounts in thousands of dollars)

|                                                                                                                                                                       |  | 2001 |         | 2002 |   | 2003    |  | 2004 |         | 2005 |  
|---------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  | ---- | ------- | ---- | - | ------- |  | ---- | ------- | ---- | -
|Pre-tax income (loss) from continuing operations                                                                                                                       |  | $    | (55,484 | )    | $ | 62,433  |  | $    | 130,314 |      | $
|                                                                                                                                                                       |  |      |         |      |   |         |  |      |         |      |  
|Fixed charges:                                                                                                                                                         |  |      |         |      |   |         |  |      |         |      |  
|Interest expense and amortization of debt discount and premium on all indebtedness                                                                                     |  |      | 20,630  |      |   | 38,215  |  |      | 28,905  |      |  
|Capitalized interest                                                                                                                                                   |  |      |        |      |   |        |  |      |        |      |  
|Appropriate portion of rentals                                                                                                                                         |  |      | 1,092   |      |   | 1,433   |  |      | 2,286   |      |  
|Preferred stock dividend requirements of consolidated subsidiaries                                                                                                     |  |      | 5,664   |      |   |        |  |      |        |      |  
|                                                                                                                                                                       |  |      |         |      |   |         |  |      |         |      |  
|Total fixed charges                                                                                                                                                    |  |      | 27,386  |      |   | 39,648  |  |      | 31,191  |      |  
|                                                                                                                                                                       |  |      |         |      |   |         |  |      |         |      |  
|Pre-tax income (loss) from continuing operations, plus fixed charges, less capitalized interest and preferred stock dividend requirements of consolidated subsidiaries |  | $    | (33,762 | )    | $ | 102,081 |  | $    | 161,505 |      | $
|                                                                                                                                                                       |  |      |         |      |   |         |  |      |         |      |  
|Ratio of earnings to fixed charges(1)                                                                                                                                  |  |      |        |      |   | 2.57    |  |      | 5.18    |      |  
|                                                                                                                                                                       |  |      |         |      |   |         |  |      |         |      |  

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