MILESTONE SCIENTIFIC INC.

                             STOCK OPTION AGREEMENT

                                                             Dated: May   , 2005

         Milestone Scientific Inc. a Delaware corporation (the "COMPANY"),
grants to Marina Co. (the "OPTIONEE"), a stock option to purchase a total of
66,667 shares of the Company's Common Stock, par value $.001 per share, at $4.37
per share on the terms and conditions set forth herein.

         1.       DURATION.

                  This option shall expire five (5) years from the date hereof
(the "TERMINATION DATE").

         2.       CHARACTERIZATION OF OPTIONS.

         Intentionally omitted.

         3.       ANTI-DILUTION PROVISIONS.

                  (a) If there is any stock dividend, stock split, or
combination of shares of Common Stock of the Company, the number and amount of
shares then subject to this option shall be proportionately and appropriately
adjusted; no change shall be made in the aggregate purchase price to be paid for
all shares subject to this option, but the aggregate purchase price shall be
allocated among all shares subject to this option after giving effect to the
adjustment.

                  (b) If there is any other change in the Common Stock of the
Company, including recapitalization, reorganization, sale or exchange of assets,
exchange of shares, offering of subscription rights, or a merger or
consolidation in which the Company is the surviving corporation, an adjustment,
if any, shall be made in the shares then subject to this option as the Board of
Directors may deem equitable. Failure of the Board of Directors to provide for
an adjustment pursuant to this subparagraph prior to the effective date of any
Company action referred to herein shall be conclusive evidence that no
adjustment is required in consequence of such action.

                  (c) If the Company is merged into or consolidated with any
other corporation, or if it sells all or substantially all of its assets to any
other corporation, then either (i) the Company shall cause provisions to be made
for the continuance of this option after such event, or







for the substitution for this option of an option covering the number and class
of securities which the Optionee would have been entitled to receive in such
merger or consolidation by virtue of such sale if the Optionee had been the
holder of record of a number of shares of Common Stock of the Company equal to
the number of shares covered by the unexercised portion of this option, or (ii)
the Company shall give to the Optionee written notice of its election not to
cause such provision to be made and this option shall become exercisable in full
(or, at the election of the Optionee, in part) at any time during a period of 20
days, to be designated by the Company, ending not more than 10 days prior to the
effective date of the merger, consolidation or sale, in which case this option
shall not be exercisable to any extent after the expiration of such 20-day
period. In no event, however, shall this option be exercisable after the
Termination Date.

         4.       INVESTMENT REPRESENTATION; LEGEND ON CERTIFICATES; SPECIAL
                  RESTRICTION ON RESALE.

                  The Optionee agrees that until such time as a registration
statement under the Securities Act of 1933 becomes effective with respect to the
option and/or the stock, the Optionee is taking this option and will take the
stock underlying this option, for his own account, for investment and not with a
view to the resale or distribution thereof. The Company shall have the right to
place upon the face of any stock certificate or certificates evidencing shares
issuable upon the exercise of this option such legend as the Board of Directors
may prescribe for the purpose of preventing disposition of such shares in
violation of the Securities Act of 1933, as now or hereafter provided.


         5.       NON-TRANSFERABILITY.

                  This option shall not be transferable by the Optionee other
than by will or by the laws of descent or distribution, and is exercisable
during the lifetime of the Optionee only by the Optionee.


         6.       CERTAIN RIGHTS NOT CONFERRED BY OPTION.

                  The Optionee shall not, by virtue of holding this option, be
entitled to any rights of a stockholder in the Company.



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         7.       EXPENSES.

                  The Company shall pay all original issue and transfer taxes
with respect to the issuance and transfer of shares of Common Stock of the
Company pursuant hereto and all other fees and expenses necessarily incurred by
the Company in connection therewith.

         8.       EXERCISE OF OPTIONS.

                  (a) This option shall be exercisable in accordance with its
terms as of the date of grant.

                  (b) An option shall be exercisable by written notice of such
exercise, in the form prescribed by the Board of Directors, to the Secretary or
Treasurer of the Company at its principal office. The notice shall specify the
number of shares for which the option is being exercised (which number, if less
than all of the shares then subject to exercise, shall be 50 or a multiple
thereof) and shall be accompanied by payment (i) in cash or by check in the
amount of the full exercise price of such options, or (ii) in such other manner
as the Board shall deem acceptable. No shares shall be delivered upon exercise
of any option until all laws, rules and regulations, which the Board of
Directors may deem applicable, have been complied with.

                  (c) The person exercising an option shall not be considered a
record holder of the stock so purchased for any purpose until the date on which
he is actually recorded as the holder of such stock in the records of the
Company.
                  (d) In the event of death of the Optionee during the term
hereof, the option may be exercised, at any time within twelve (12) months
following the date of death, by the Optionee's estate or by a person who
acquired the right to exercise this option by bequest or inheritance, but only
to the extent of the right that would have accrued had the Optionee continued
living one (1) month after the date of death. Notwithstanding the provisions of
this Section (d), in no event shall this option be exercisable after the
Termination Date.





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         9. Nothing herein shall be deemed to create any employment agreement
between the Optionee and the Company.

                                   MILESTONE SCIENTIFIC INC.

                                   By:
                                       -----------------------------------------
                                       Leonard A. Osser, Chairman & CEO


Accepted as of the date
first set forth above.


OPTIONEE:


MARINA CO.



By:
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