UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

MEMORANDUM 

Date: 20-JAN-2015 

OFFICE OF CHEMICAL SAFETY AND 

POLLUTION PREVENTION 

Subject: Sedaxane. Petition for the Establishment of Permanent Tolerances for Seed 

Treatment Use on Cotton and Sugar Beet. Update to Summary of Analytical 

Chemistry and Residue Data. 

PC Code: 129223 

Decision No.: 489552 

Petition No.: 4F8263 

Risk Assessment Type: NA 

TXRNo.: NA 

MRlDNo.: NA 

DP Barcode: 0425 112 

Registration No.: 100-1381, 100-RLLA 

Regulatory Action: Section 3 Registration 

Case No.: NA 

CAS No.: 874967-67-6 

40 CFR: § 180.665 

From: 

Ris

William 

k Assessment 

H. Donovan, 

Branch 

Ph.D., 

(RAB) 

Senior 

V 

Chemist {A)~ u;:J, ~ 

Health Effects Division (7509P) 

Through: MichaelS. Metzger, Branch Chief / d (} (}) /A _, 

RAB V & VII [L;\V{_ v{' ;L/ - Health Effects Division (7509P) · 

To: Driss Benmhend, Risk Manager 

Fungicide-Herbicide Branch 

Registration Division (7505P) 

Jennifer Urbanski, Risk Manager 

Invertebrate-Vertebrate Branch 3 

Registration Division (7505P) 

A residue chemistry summary memo for the new use request of sedaxane inion cotton and sugar 

beet was recently completed (D423822, W. Donovan, 19-DEC-2014). In the process of 

preparing the risk assessment for this action, the need for an update to the residue chemistry 

summary memo was identified. Accordingly, the following tables and section should replace the 

corresponding tables and section of the 19-DEC-201 4 memo. 

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Sedaxane Update to Summary of Analytical Chemistry and Residue Data D425112 

Table 1. Tolerance Summary for Sedaxane. 

Commodity Proposed Tolerance Recommended Comments; Correct Commodity 

(ppm) Tolerance (ppm) Definition 

Cotton, undelinted seed 0.01 0.01 Cotton, undelinted seed 

Cotton, gin byproducts 0.01 0.01 Cotton, gin byproducts 

Beet, sugar 0.01 0.01 Beet, sugar, roots 

2.2.3 Revisions to Petitioned-For Tolerances 

None 

Table3.3 Summary of Directions for Proposed New Uses of Sedaxane. 

Formulation Application Rate 

Application [EPA File lb ai/1 00 lb seed Use Directions and Limitations Type Symbol No.] [g ai/1 00 kg seed] 

(mg ai/seed) 

Cotton 

Do not use seed for feed, food or oil purposes. Store 

away from feeds and foodstuffs. Following sedaxane 

treated seeds except potato seed pieces: All crops that 

have not been treated with sedaxane may be planted 

30 days after planting sedaxane treated seeds. All 

crops treated with sedaxane may be replanted 

immediately with the exception of potato. Following 

potato seed pieces treated with sedaxane: No 

sedaxane treated potato seeds may be planted for a 

4.3 lb/gal FS 0.0027-0.020 24-month period following planting of sedaxane 

Seed treatment [2.7-20] treated potato seed pieces. All crops treated with [100- 1347] (0.002-0.0 17)1 sedaxane other than potato may be replanted 

immediately. No sedaxane treated potato seeds may 

be planted for a 24-month period following planting 

of sedaxane treated potato seed pieces. Excess treated 

seed may be used for ethanol production only if(l) 

by-products are not used for livestock feed and (2) no 

measurable residues of pesticide remain in ethanol byproducts that are used for agronomic practice. The 

maximum number of applications per year is 2. 

Sugar Beet (not allowed on sugar beets grown for seed production) 

4.3 lb/gal FS 0.044-0.66 

Seed treatment [44-660]2 As above [100- 1347] (0.0050 - 0.075) 

1 Assuming an average seed size of 5,500 seeds/pound, as indicated in the Use Rate section of the label. However, 

HED assumes 4,500 seeds/pound [J. Becker and S. Ratnayake, "Acres Planted per day and Sowing Rates of Crops 

Grown in the U.S." 24-MAR-2011], which implies a maximum application rate of0.020 mg sedaxane/seed. 

2 Calculated assuming 40000 seeds/lb. Label expresses use rate in terms offl oz and g ai per 100,000 seeds: 0.03 -

0.49 fl oz product/100,000 seeds and 0.50 - 7.5 g ai/100,000 seeds. 

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