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Tivida ® FL 2500 0 ~ 

I . Ppoduct and c®mpany uderafitucaftuon 

Product name : Tivida"I FL 2500 

Product code : 1.02458 

Supplier : EMD Chemicals 

An Affiliate of Merck KGaA, Darmstadt Germany 

One Internationa' Plaza 

Suite 300 

Philadelphia, PA 19113 

888-367-3275 

Material uses : Coating agents 

Validation date : 3/11/2014. 

In case of emergency : Chemtrec (USA): 800-424-9300 

Canutec (Canada): 613-996-6666 

24 Hours/Day; 7 Days/Week 

2 . Hazards odentoficatu®n 

Emergency overvievv 

Physical state 

OSHA/HCS status 

Routes of entry 

Inhalation 

Ingestion 

Sbcin 

Eyes 

Medical conditions 

aggravated by overexposure 

WARNING! 

FLAMMABLE LIQUID AND VAPOR. CAUSES SKIN IRRITATION. SERIOUS EYE 

DAMAGE/ EYE IRRITATION May cause drowsiness and dizziness. CONTAINS 

MATERIAL THAT MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL 

DATA. 

Liquid. 

This material is considered hazardous by the OSHA Hazard Communication Standard ( 

29 CFR 1910.1200). 

Dermal contact. Eye contact. Inhalation. Ingestion. 

May be hazardous in case of inhalation (lung irritant). 

May be hazardous in case of ingestion. 

Irritating to skin. 

Severely irritating to eyes. Risk of serious damage to eyes. 

Repeated or prolonged inhalation of vapors may aggravate respiratory rr:edical 

conditions. 

Seetoxicological information (section 11) 

D®mp®situ®n/int'®rrnatu®n ®n Angred°uents 

Name CAS number % by weight 

1-methoxy-2-prcpanol 107-98-2 55 

Trade secret acid, TSRN 13-2666399-5862P Trade secret 30 

water 7732-18-5 15 

*Chemical Identity withheld as a Trade Secret under the OSHA Hazard Communication Standard, 29CFR 1910.1200 (i) (1). 

~ . I~ur~t ~o~l ~~~~a~~c~~ 

Eye contact : Check for and remove any contact lenses. Immediately flush eyes with plenty of water 

for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical 

attention immediately. 

Skin contact : In case of contact, immediately flush skin with plenty of water for at least 15 minutes 

while removing contaminated clothing and shoes. Wash clothing before reuse. Clean 

shoes thoroughly before reuse. Get medical attention immediately. 

Continued on next page 
Tividal FL 2500 1.02458 217 

4. Mrst aM measures 

Inhalation : Move exposed person to fresh air. If not breathing, if breathing is irregular or if 

respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. 

Loosen tight clothing such as a collar, tie, belt or waistband. Get medical at;ention 

immediately. 

Ingestion : Wash out mouth with water. Do not induce vomiting unless directed to do so by medical 

personnel. Never give anything by mouth to an unconscious person. Get medical 

attention immediately. 

5 e Fire-fighting measures 

Flammability of the product : Combustible material. 

Extinguishing media : Use dry chemical, COz, water spray (fog) or foam. 

iUot suitable : Do not use water jet. 

Special exposure hazards : Promptly isolate the scene by removing all persons from the vicinity of the incident if 

there is a fire. No action shall be taken involving any personal risk or without suitable 

training. Move containers from fire area if this can be done without risk. Use water 

spray to keep fire-exposed containers cool. 

Hazardous thermal : Decomposition products may include the following materials: 

decomposition products carbon dioxide 

carbon monoxide 

Special protective : Fire-fighters should wear appropriate protective equipment and self-contained breathing 

equipment for fire-fighters apparatus (SCBA) with a full face-piece operated in positive pressure mode. 

Special remarks on fire : Combustible material. Vapors are heavier than air and niay spread along floors. Forms 

hazards explosive mixtures with air on intense heating. Development of hazardous combustion 

gases or vapors possible in the event of fire. Ambient fire may liberate hazardous vapors 

. The following may develop in event of fire: hydrogen fluoride 

5 e Qcc ~,dierficai Wease measures 

Personal precautions : No action shall be taken involving any personal risk or without suitable training. 

Evacuate surrounding areas. Keep unnecessary and unprotected personnel from 

entering. Do not touch or walk through spilled material. Shut off all ignition sources. No 

flares, smoking or flames in hazard area. Avoid breathing vapor or mist. Provide 

adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put 

on appropriate personal protective equipment (see Section 8). 

Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterNays, drains 

and sewers. Inform the relevant authorities if the produc ,~ has caused environmental 

pollution (sewers, waterways. soil or air). 

I'dtethods for cleaninq up 

Spill : Stop leak if without risk. Move containers from spill area. Approach release from 

upwind. Prevent entry into sewers, water courses, basements or confined areas. 

Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth, 

vermiculite or diatomaceous earth and place in container for disposal according to local 

regulations (see section 13). Use spark-proef tools and explosion-proof equipment. 

Dispose of via a licensed waste disposal contractor. Contaminated abscrbent material 

may pose the same hazard as the spilled product. Note: see section 1 for emergency 

contact information and section 13 `or waste disposal. Dilute with water and mop up if 

water-soluble or absorb with an inert dry material and place in an appropriate waste 

disposal container. 

~ Continued on next page 
L_ 

 Tivida l FL 2500 1.02458 317 

7. Handling and storage 

Handling : Do not get in eyes, on skin or on clothing. Avoid breathing vapor or mist. Use only with 

adequate ventilation. Keep in the original container or an approved alternative made 

from a compatible material, kept tightly closed when not in use. 

Storage : Store in accordance with local regulations. Store in a segregated and approved area. 

Store in original container, protected from direct sunlight. Eliminate all ignition sources. 

Separate from oxidizing materials. Keep container tightly closed and sealed until ready 

for use. Containers that have been opened must be carefully resealed and kept upright 

to prevent leakage. Store between the following temperatures: 5 to 30°C (41 to 86 0 F). 

8 . Exposure controls/personal protection 

Ingredient Exposure limits 

1-methoxy-2-propanol ACGIH TLV (United States, 6/2013). 

TWA: 50 ppm 8 hour(s). 

TWA: 184 mg/m' 8 hour(s). 

STEL: 100 ppm 15 minute(s). 

STEL: 369 mg/m3 15 minute(s). 

OSHA PEL 1989 (United States, 3/1989). 

TWA: 100 ppm 8 hour(s). 

TWA: 360 mg/m' 8 hour(s). 

STEL: 150 ppm 15 minute(s). 

STEL: 540 mg/m' 15 minute(s). 

NIOSH REL (United States, 10/2013). 

TWA: 100 ppm 10 hour(s). 

TWA: 360 mg/m' 10 hour(s). 

STEL: 150 ppm 15 minute(s). 

STEL: 540 mg/m3 15 minute(s). 

Consult local authorities for acceptable exposure limits. 

Engineering measures : Use only with adequate ventilation. Use process enclosures, local exhaust ventilation or 

other engineering controls to keep worker exposure to airborne contaminants below any 

recommended or statutory limits. The engineering controls also need to keep gas, vapor 

or dust concentrations below any lower explosive limits. Use explosion-proof ventilation 

equipment. 

Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before 

eating, smoking and using the lavatory and at the end of the working period. Appropriate 

techniques should be used to remove potentially contaminated clothing. Wash 

contaminated clothing before reusing. Ensure that eyewash stations and safety showers 

are close to the workstation location. 

Personal protection 

Respiratory : Vapor respirator or self-contained breathing apparatus (SCBA). Ensure an MSHA/ 

NIOSH-approved respirator is used. 

Hands : Chemical-resistant, corrosive resistant, impervious to FL 2300 gloves complying with an 

approved standard should be worn at all times when handling chemical products if a risk 

assessment indicates this is necessary. 

Eyes : Safety eyewear complying with an approved standard should be used when a risk 

assessment, by a qualified Industrial Hygienist, indicates their use to avoid exposure to 

liquid splashes, mists or dusts. 

Skin : Personal protective equipment for the body should be selected based on the task being 

performed and the risks involved and should be approved by a specialist before handling 

this product. 

Continued on next page 
Tivida`" FL 2500 1.02458 417 

9 . ~ hysecal and chemoca9 pr®pertses 

Physical state : Liquid. 

Flash point : Closed cup: 31 °C (87.8°F) 

Information refers to the main component 

Color : Light yellow 

Odor : Characteristic. 

pH ; Not available. 

Boiling/condensation point : Not available. 

IVlelting/freezing point : Not available. 

Relative density : Not available. 

llapor pressure : Not available. 

Vapor density : Not available. 

Odor threshold : Not available. 

Evaporation rate : Not applicable 

vOC : 55 % (w/w) 

Solubility : Soluble 

10 . StaboMy and rr°eactovity 

Chemical stability : The product is stable. 

T®xec®0®gical onf®rmati®n 

Acute toxicity 

Product/ingredient name Test Route Species Result 

1-methoxy-2-propanol LD50 Dermal Rabbit 13 g/kg 

LD50 Rat 3720 mg/kg 

Intraperitoneal 

LD50 Intravenous Rat 4200 mg/kg 

LD50 Oral Mouse 11700 mg/kg 

LD50 Oral Rat 6600 mg/kg 

LD50 Oral Rabbit 5700 mg/kg 

LD50 Rat 7800 mg/kg 

Subcutaneous 

LDLo Oral Rat 3739 mg/kg 

LC50 Inhalation Rat 10000 ppm 

Gas. 

Species Score Observation 

Rabbit - - 

Rabbit - - 

EPA NIOSH I'dTP OSHA 

- None. - - 

Irritation/Corrosion 

Product/ingredient name 

1-methoxy-2-propanol 

Carcinoqenicity 

Classification 

Product/ingredient name 

1-methoxy-2-propanol 

Result 

Eyes - Mild irritant 

Skin - Mild irritant 

ACGIFi IARC 

A4 - 

No known significant effects or critical hazards. 

Niutaqenicity 

No known significant effects or critical hazards. 

Teratogenicity 

No known significant effects or critical hazards. 

~ntfnued on next page 
L— 

 Tivida ~" FL 2500 1.02458 517 

12. Ec®I®gical inf®rmatu®n 

Acauatic ecotoxicity 

Product/ingredient name Result Species Exposure 

Tivida" FL 2500 EC50 >100 mg/I Daphnia 48 hours 

EC50 >100 mg/I Algae 72 hours 

Environmental effects : No known significant effects or critical hazards. 

13 . ®isp®sal c®nsudlerati®ns 

The information presented only applies to the material as supplied. The identification based on characteristic(s) or listing 

may not apply if the material has been used or othenNise contaminated. It is the responsibility of the waste generator to 

determine the toxicity and physical properties of the material generatec to determine the proper waste identification and 

disposal methods in compliance with applicable regulations. Disposal should be in accordance with applicable regional, 

national and local laws and regulations. 

1~ . Transp®rt inf®rrnati®n 

Regulatory UN number Proper shipping Classes PG* Label Additional 

information name information 

DOT Classification UN3092 1-Methoxy-2-propanol 3 III - 

IATA-DGR Class UN3092 1-Methoxy-2-propanol 3 III 

PG' : Packing group 

I~egu ~ at®ry unformata®n 

United States 

U.S. Federal regulations : FOR RESEARCH AND DEVELOPPJIENT USE ONLY. Use under the supervision of 

qualified personnel. 

SARA 302/304/311/312 extremely hazardous substances: No products were found. 

SARA 302/304 emergency planning and notification: No products were found. 

SARA 302/304/311/312 hazardous chemicals: 1-methoxy-2-propanol 

SARA 311/312 MSDS distribution - chemical inventory - hazard identification: 1- 

methoxy-2-propanol: Fire hazard, Immediate (acute) health hazard, Delayed (chronic) 

health hazard 

Connecticut Carcinogen : None of the components are listed. 

Reporting 

Connecticut Hazardous : None of the components are listed. 

Material Survey 

Florida substances : None of the components are listed. 

Illinois Chemical Safety Act : None of the components are listed. 

Illinois Toxic Substances : None of the components are listed 

Disclosure to Employee Act 

Louisiana Spill 

Louisiana Reporting 

fdlassachusetts Spill 

PUlassachusetts Substances 

Minnesota Hazardous 

Substances 

: None of the components are listed 

: None of the components are listed 

: None of the components are listed 

: None of the components are listed 

: None of the components are listed 

Continued on next page 
Tivida'", FL 2500 1.02458 617 

15 . Regula$®rry unf®rmatu®n 

Michigan Critical Material 

filew Jersey Toxic 

Catastrophe Prevention Act 

New Jersey Spill 

New Jersey Hazardous 

Substances 

New York Toxic Chemical 

Release Reporting 

New York Acutely 

Hazardous Substances 

Pennsylvania RTK 

Hazardous Substances 

Rhode Island Hazardous 

Substances 

Canada 

WHMIS (Canada) : Class B-2: Flammable liquid 

None of the components are listed. 

None of the components are listed. 

None of the components are listed. 

None of the components are listed. 

None of the components are listed. 

None of the components are listed. 

None of the components are listed. 

None of the components are listed. 

Canadian lists : CEPA Toxic substances: None of the components are 'isted. 

Canadian ARET: None of the components are listed. 

Canadian NPRI: None of the components are listed. 

Alberta Designated Substances: None of the components are listed. 

Ontario Designated Substances: None of the components are listed. 

Quebec Designated Substances: None of the components are listed. 

This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the 

MSDS contains all the information required by the Controlled Products Regulations. 

EU reclulations 

Risk phrases : R10- Flammable. 

R67- Vapors may cause drowsiness and dizziness. 

Safety phrases : S2- Keep out of the reach of children. 

International requlations 

16. ®fhec unf®a°mafi®n 

Hazardous Material 

Information System (U.S.A.) 

Health 

Flammability 

Physical 

3 

3 

hazards 10 

Caution: HMISO ratings are based on a 0-4 rating scale, with 0 representing minimal hazards or risks, and 4 

representing significant hazards or risks Although HMISO ratings are not required on MSDSs under 29 CFR 1910. 

1200, the preparer may choose to provide them. HMISO ratings are to be used with a fully implemented HMISO 

program. HMISO is a registered mark of the hlational Paint & Coatings Association (NPCA). HMISO materials may 

be purchased exclusively from J. J. 14eller (800) 327-6868. 

National Fire Protection 

Association (U.S.A.) 

^ , Flammability 

Health > Instability 

Special 

Continued on next page 
TividaI FL 2500 1.02458 7/7 

16. Other unf®rmafl®n 

Other special : No additional information. 

considerations 

Notice to reader 

The statements contained herein are based upon technical data that EhiID Millipore Corporation believes to be 

reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency 

handling of the material by a properly trained person having the necessary technical skills. Users should consider 

these data only as a supplement to other information gathered by them and must make independent 

determinations of suitability and completeness of information from all sources to assure proper use, storage and 

disposal of these materials and the safety and health of employees and customers and the protection of the 

environment. EfVID MILLIPORE CORPORATION IVIAKES iV0 REPRESENTATIOfd OR WARRAIVTY OF AhlY KIfVD, 

EXPRESS OR IMPLIED, INCLUDIIVG f1flERCHANTABILITY OR FITNESS FOR A PARTICULAR USE, NUITH RESPECT 

TO THE IIVFORMATIOIV HEREIIV OR THE PRODUCT TO WHICH THE INFORMATIOIV REFERS.