Federal Register / Vol. 75, No. 213 / Thursday, November 4, 2010 / Notices 67963 

ENVIRONMENTAL PROTECTION 

AGENCY 

[FRL–9220–2] 

Availability of Draft NPDES General 

Permits MAG580000 and NHG580000 

for Discharges From Publicly Owned 

Treatment Works Treatment Plants 

(POTW Treatment Plants) and Other 

Treatment Works Treating Domestic 

Sewage in the Commonwealth of 

Massachusetts and the State of New 

Hampshire 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice. 

SUMMARY: The Director of the Office of 

Ecosystem Protection, EPA–New 

England, is issuing a notice of 

availability for public comment of the 

draft National Pollutant Discharge 

Elimination System (NPDES) general 

permits for certain Publicly Owned 

Treatment Works Treatment Plants 

(POTW treatment plants) and Other 

Treatment Works Treating Domestic 

Sewage (collectively, ‘‘facilities’’) in the 

Commonwealth of Massachusetts 

(including both Commonwealth and 

Indian country lands) and the State of 

New Hampshire. Throughout this 

document, these two permits are 

collectively referred to as the ‘‘Publicly 

Owned Treatment Works General 

Permit’’ (‘‘POTW GP’’ or the ‘‘General 

Permit’’). The draft General Permits, 

upon final issuance, will replace the 

prior POTW GP which expired on 

September 23, 2010. 

The draft POTW GP establishes 

Notice of Intent (NOI) requirements as 

well as effluent limitations, standards, 

and prohibitions for facilities that 

discharge to fresh and marine waters. 

Coverage under these General Permits is 

available to facilities in Massachusetts 

classified as minor facilities and to 

facilities in New Hampshire classified 

as major or minor facilities. Owners 

and/or operators of these facilities, 

including those facilities authorized to 

discharge under the current General 

Permit, will be required to submit an 

NOI to be covered by the reissued 

POTW GP to both EPA-New England 

and the appropriate State agency, in 

accordance with the notification 

requirements of the General Permit. 

Following EPA and the State review of 

the NOI, the facility will receive a 

written notification from EPA of permit 

coverage and authorization to discharge 

under the General Permit. The eligibility 

requirements for permit coverage, 

including the requirement that a facility 

have a receiving water dilution factor 

equal to or greater than 50, are provided 

in the General Permit. The General 

Permit does not cover new sources as 

defined under 40 CFR 122.2. 

The purpose of this document is to 

solicit public comments on the 

proposed General Permits. 

Public Comment Period: The public 

comment period is from November 4, 

2010 to December 6, 2010. Interested 

persons may submit written comments 

on the draft General Permit to the EPARegion I at the address listed below. 

Within the comment period, interested 

persons may also request, in writing, 

that EPA hold a public hearing pursuant 

to 40 CFR Section 124.12, concerning 

the draft General Permits. Such requests 

shall state the nature of the issues 

proposed to be raised at the hearing. A 

public hearing may be held at least 

thirty days after public notice whenever 

the Regional Administrator finds that 

response to this notice indicates 

significant public interest. In reaching a 

final decision on this draft permit, the 

Regional Administrator will respond to 

all significant comments and make 

responses available to the public at 

EPA’s Boston office. All comments and 

requests for public hearings must be 

postmarked or delivered before 

midnight December 6, 2010, the close of 

the public comment period. All public 

comments or requests for a public 

hearing must be submitted to the 

address below. 

ADDRESSES: Written comments on the 

draft General Permit may be hand 

delivered or mailed to Meridith Timony, 

EPA-Region 1, Office of Ecosystem 

Protection, OEP06–1, 5 Post Office 

Square-Suite 100, Boston, 

Massachusetts 02109–3912; or sent via 

e-mail to Timony.meridith@epa.gov. No 

facsimiles (faxes) will be accepted. 

FOR FURTHER INFORMATION CONTACT: For 

further information contact Meridith 

Timony at 617–918–1533, between the 

hours of 9 a.m. and 5 p.m., Monday 

through Friday, excluding holidays. The 

draft General Permits are based on an 

administrative record available for 

public review at EPA-Region 1, Office of 

Ecosystem Protection, 5 Post Office 

Square-Suite 100, Boston, 

Massachusetts 02109–3912, Monday 

through Friday from 9 a.m.–5 p.m., 

excluding holidays. The draft General 

Permit and a Fact Sheet may also be 

viewed over the Internet via the EPARegion I Web site at http:// 

www.epa.gov/region1/npdes/potwgp.html. To obtain a paper copy of the 

documents, please contact Meridith 

Timony using the contact information 

provided above. A reasonable fee may 

be charged for copying requests. 

Dated: October 19, 2010. 

Ira W. Leighton, 

Acting Regional Administrator, Region 1. 

[FR Doc. 2010–27763 Filed 11–3–10; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

[EPA–HQ–OPPT–2010–0877; FRL–8849–8] 

Endocrine Disruptor Screening 

Program (EDSP); Announcing the 

Availability of a Draft for Weight-ofEvidence Guidance Document: 

Evaluating Results of EDSP Tier 1 

Screening To Identify Candidate 

Chemicals for Tier 2 Testing 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice. 

SUMMARY: EPA is announcing the 

availability for public review and 

comment of a draft guidance document 

titled, ‘‘Weight-of-Evidence Guidance 

Document: Evaluating Results of EDSP 

Tier 1 Screening to Identify Candidate 

Chemicals for Tier 2 Testing.’’ This 

action is in compliance with a directive 

from the House Appropriations 

Committee FY 2010 Report directing the 

EPA to develop and publish criteria by 

October 30, 2010, for evaluating results 

of Tier 1 screening and determining 

whether a chemical should undergo Tier 

2 analysis. The purpose of the weightof-evidence (WoE) document is to set 

forth some of the general principles, 

criteria, and considerations EPA 

generally believes to be relevant under 

a WoE approach for evaluating data 

submitted as part of EPA’s two-tiered 

paradigm for screening and testing 

chemicals for endocrine activity (i.e., 

estrogen, androgen, and thyroid 

hormonal systems; E, A, and T) under 

the EDSP. This document provides a 

transparent scientific approach for 

broadly evaluating Tier 1 screening data 

to detect an interaction with E, A, and/ 

or T hormonal systems and determine if 

additional Tier 2 testing is necessary. 

DATES: Comments must be received on 

or before January 3, 2011. 

ADDRESSES: Submit your comments, 

identified by docket identification (ID) 

number EPA–HQ–OPPT–2010–0877, by 

one of the following methods: 

• Federal eRulemaking Portal: http:// 

www.regulations.gov. Follow the on-line 

instructions for submitting comments. 

• Mail: Document Control Office 

(7407M), Office of Pollution Prevention 

and Toxics (OPPT), Environmental 

Protection Agency, 1200 Pennsylvania 

Ave., NW., Washington, DC 20460– 

0001. 


jlentini on DSKJ8SOYB1PROD with NOTICES
67964 Federal Register / Vol. 75, No. 213 / Thursday, November 4, 2010 / Notices 

• Hand Delivery: OPPT Document 

Control Office (DCO), EPA East Bldg., 

Rm. 6428, 1201 Constitution Ave., NW., 

Washington, DC. Attention: Docket ID 

Number EPA–HQ–OPPT–2010–0877. 

The DCO is open from 8 a.m. to 4 p.m., 

Monday through Friday, excluding legal 

holidays. The telephone number for the 

DCO is (202) 564–8930. Such deliveries 

are only accepted during the DCO’s 

normal hours of operation, and special 

arrangements should be made for 

deliveries of boxed information. 

Instructions: Direct your comments to 

docket ID number EPA–HQ–OPPT– 

2010–0877. EPA’s policy is that all 

comments received will be included in 

the docket without change and may be 

made available on-line at http:// 

www.regulations.gov, including any 

personal information provided, unless 

the comment includes information 

claimed to be Confidential Business 

Information (CBI) or other information 

whose disclosure is restricted by statute. 

Do not submit information that you 

consider to be CBI or otherwise 

protected through regulations.gov or email. The regulations.gov Web site is an 

‘‘anonymous access’’ system, which 

means EPA will not know your identity 

or contact information unless you 

provide it in the body of your comment. 

If you send an e-mail comment directly 

to EPA without going through 

regulations.gov, your e-mail address 

will be automatically captured and 

included as part of the comment that is 

placed in the docket and made available 

on the Internet. If you submit an 

electronic comment, EPA recommends 

that you include your name and other 

contact information in the body of your 

comment and with any disk or CD–ROM 

you submit. If EPA cannot read your 

comment due to technical difficulties 

and cannot contact you for clarification, 

EPA may not be able to consider your 

comment. Electronic files should avoid 

the use of special characters, any form 

of encryption, and be free of any defects 

or viruses. 

Docket: All documents in the docket 

are listed in the docket index available 

at http://www.regulations.gov. Although 

listed in the index, some information is 

not publicly available, e.g., CBI or other 

information whose disclosure is 

restricted by statute. Certain other 

material, such as copyrighted material, 

will be publicly available only in hard 

copy. Publicly available docket 

materials are available electronically at 

http://www.regulations.gov, or, if only 

available in hard copy, at the OPPT 

Docket. The OPPT Docket is located in 

the EPA Docket Center (EPA/DC) at Rm. 

3334, EPA West Bldg., 1301 

Constitution Ave., NW., Washington, 

DC. The EPA/DC Public Reading Room 

hours of operation are 8:30 a.m. to 4:30 

p.m., Monday through Friday, excluding 

legal holidays. The telephone number of 

the EPA/DC Public Reading Room is 

(202) 566–1744, and the telephone 

number for the OPPT Docket is (202) 

566–0280. Docket visitors are required 

to show photographic identification, 

pass through a metal detector, and sign 

the EPA visitor log. All visitor bags are 

processed through an X-ray machine 

and subject to search. Visitors will be 

provided an EPA/DC badge that must be 

visible at all times in the building and 

returned upon departure. 

FOR FURTHER INFORMATION CONTACT: For 

technical information contact: Don 

Bergfelt, Office of Science Coordination 

and Policy (7203M), Environmental 

Protection Agency, 1200 Pennsylvania 

Ave., NW., Washington, DC 20460– 

0001; telephone number: (202) 564– 

8472; e-mail address: 

bergfelt.don@epa.gov. 

For general information contact: The 

TSCA–Hotline, ABVI–Goodwill, 422 

South Clinton Ave., Rochester, NY 

14620; telephone number: (202) 554– 

1404; e-mail address: TSCA– 

Hotline@epa.gov. 

SUPPLEMENTARY INFORMATION: 

I. General Information 

A. Does this action apply to me? 

This action is directed to the public 

in general. You may be potentially 

affected by this action if you produce, 

manufacture, use, consume, work with, 

or import industrial or pesticide 

chemicals. To determine whether you or 

your business may be affected by this 

action, you should carefully examine 

section 408(p) of the Federal Food, 

Drug, and Cosmetic Act (FDCA) (21 

U.S.C. 346a(p)) and the Safe Drinking 

Water Act (42 U.S.C. 300j–17). 

Potentially affected entities may 

include, but are not limited to: 

• Chemical manufacturers, importers 

and processors (NAICS code 325), e.g., 

persons who manufacture, import, or 

process chemical substances. 

• Pesticide, fertilizer, and other 

agricultural chemical manufacturers 

(NAICS code 3253), e.g., persons who 

manufacture, import or process 

pesticide, fertilizer, and agricultural 

chemicals. 

• Scientific research and 

development services (NAICS code 

5417), e.g., persons who conduct testing 

of chemical substances for endocrine 

effects. 

This listing is not intended to be 

exhaustive, but rather provides a guide 

for readers regarding entities likely to be 

affected by this action. Other types of 

entities not listed in this unit could also 

be affected. The North American 

Industrial Classification System 

(NAICS) codes have been provided to 

assist you and others in determining 

whether this action might apply to 

certain entities. If you have any 

questions regarding the applicability of 

this action to a particular entity, consult 

the technical person listed under FOR

FURTHER INFORMATION CONTACT. 

B. What should I consider as I prepare 

my comments for EPA? 

1. Submitting CBI. Do not submit this 

information to EPA through 

regulations.gov or e-mail. Clearly mark 

the part or all of the information that 

you claim to be CBI. For CBI 

information in a disk or CD–ROM that 

you mail to EPA, mark the outside of the 

disk or CD–ROM as CBI and then 

identify electronically within the disk or 

CD–ROM the specific information that 

is claimed as CBI. In addition to one 

complete version of the comment that 

includes information claimed as CBI, a 

copy of the comment that does not 

contain the information claimed as CBI 

must be submitted for inclusion in the 

public docket. Information so marked 

will not be disclosed except in 

accordance with procedures set forth in 

40 CFR part 2. 

2. Tips for preparing your comments. 

When submitting comments, remember 

to: 

i. Identify the document by docket ID 

number and other identifying 

information (subject heading, Federal 

Register date and page number). 

ii. Follow directions. The Agency may 

ask you to respond to specific questions 

or organize comments by referencing a 

Code of Federal Regulations (CFR) part 

or section number. 

iii. Explain why you agree or disagree; 

suggest alternatives and substitute 

language for your requested changes. 

iv. Describe any assumptions and 

provide any technical information and/ 

or data that you used. 

v. If you estimate potential costs or 

burdens, explain how you arrived at 

your estimate in sufficient detail to 

allow for it to be reproduced. 

vi. Provide specific examples to 

illustrate your concerns and suggest 

alternatives. 

vii. Explain your views as clearly as 

possible, avoiding the use of profanity 

or personal threats. 

viii. Make sure to submit your 

comments by the comment period 

deadline identified. 


jlentini on DSKJ8SOYB1PROD with NOTICES
Federal Register / Vol. 75, No. 213 / Thursday, November 4, 2010 / Notices 67965 

II. Background 

A. What action is the agency taking? 

EPA is announcing the availability of 

a draft guidance document titled, 

‘‘Weight-of-Evidence Guidance 

Document: Evaluating Results of EDSP 

Tier 1 Screening to Identify Candidate 

Chemicals for Tier 2 Testing.’’ This 

document invites the public to review 

and comment on the guidance 

document, which is available 

electronically at regulations.gov (http:// 

www.regulations.gov) using docket ID 

number EPA–HQ–OPPT–2010–0877 

and the EDSP Web site http:// 

www.epa.gov/endo. 

This document was prepared to 

provide a transparent, scientific 

approach to set forth some general 

principles, criteria, and considerations 

EPA generally believes to be relevant 

using a WoE approach to evaluate data 

submitted as part of EPA’s EDSP 

involving a battery of validated Tier 1 

screening assays as described in a notice 

published in the Federal Register issue 

of October 21, 2009 (74 FR 54415) (FRL– 

8432–6). The criteria discussed in this 

document are based, in part, on EPA’s 

experience in developing and applying 

risk assessment guidelines involving 

cancer, reproductive and developmental 

toxicity, and ecological toxicity. 

Important considerations include the 

use of expert judgment formed through 

the scientific process, current 

understanding of endocrine 

mechanisms of toxicity, and knowledge 

of other fields of toxicology (e.g., 

developmental, reproductive, 

neurological and immunological 

toxicology, and toxicokinetics). 

Principles articulated in this document 

are equally applicable to a WoE 

evaluation of data from individual 

assays with multiple endpoints, as well 

as across the whole suite of assays in the 

EDSP Tier 1 screening battery. In 

addition, these principles would be 

generally applicable to the review of 

other scientifically relevant information 

(OSRI) submitted in response to test 

orders that request OSRI to be 

considered in lieu of designated 

screening assays in the Tier 1 battery. 

In general, the EDSP is a two-tiered 

paradigm for screening and testing 

chemicals with the potential to interact 

with the endocrine system. Tier 1 

screening consists of a battery of 

complementary in vitro and short term 

in vivo assays designed to maximize 

sensitivity for detecting interactions 

with the E, A, and/or T hormonal 

systems; whereas, Tier 2 testing consists 

of a group of individual in vivo tests 

designed to include males and females 

with an intact hypothalamic-pituitarygonadal axis, multiple pathways of 

exposure and life-stages, and various 

taxa to further identify and characterize 

chemical-induced interactions with E, 

A, and/or T for risk assessment. The 

diversity in endocrine endpoints within 

and among the Tier 1 screening assays 

is expected to provide corroborating 

information and support a WoE 

evaluation to yield a decision as to 

whether or not the chemical indentified 

in Tier 1 requires additional testing in 

Tier 2. 

B. What is the agency’s authority for 

taking this action? 

Section 408(p) of FFDCA requires 

EPA to ‘‘develop a screening program, 

using appropriate validated test systems 

and other scientifically relevant 

information, to determine whether 

certain substances may have an effect in 

humans that is similar to an effect 

produced by a naturally occurring 

estrogen, or such other endocrine effect 

as [EPA] may designate.’’ (21 U.S.C. 

346a(p)). The statute generally requires 

EPA to ‘‘provide for the testing of all 

pesticide chemicals.’’ (21 U.S.C. 

346a(p)(3)). ‘‘Pesticide chemical’’ is 

defined as ‘‘any substance that is a 

pesticide within the meaning of the 

Federal Insecticide, Fungicide, and 

Rodenticide Act (FIFRA), including all 

active and inert ingredients of such 

pesticide.’’ (21 U.S.C. 321(q)(1)). 

List of Subjects 

Environmental protection, Endocrine 

disruptors, Screening assays, Weight-ofevidence. 

Dated: October 27, 2010. 

Stephen A. Owens, 

Assistant Administrator, Office of Chemical 

Safety and Pollution Prevention. 

[FR Doc. 2010–27897 Filed 11–3–10; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

[FRL–9220–9] 

Announcement of Local Government 

Advisory Committee Members 

AGENCY: Environmental Protection 

Agency. 

ACTION: Notice. 

SUMMARY: The U.S. Environmental 

Protection Agency announces that 

Administrator Lisa P. Jackson has 

appointed 29 local, State, and Tribal 

elected and appointed officials from 

across the country to serve on the EPA’s 

Local Government Advisory Committee 

(LGAC). The Committee’s purpose will 

be to give advice and recommendations 

on a broad range of environmental 

issues affecting local governments. 

These new appointments include: 

Mayors (Large Cities) 

Phil Gordon, Mayor, Phoenix, 

Arizona. 

John W. Hickenlooper, Mayor, 

Denver, Colorado. 

Mayors (Moderate Sized Cities) 

Jennifer Hosterman, Mayor, 

Pleasanton, California. 

Terry Bellamy, Mayor, Asheville, 

North Carolina. 

Elizabeth Kautz, Mayor, Burnsville, 

Minnesota. 

Teresa Coons, Mayor, Grand Junction, 

Colorado. 

Dana L. Redd, Mayor, Camden, New 

Jersey. 

Mayors (Small Cities and Towns) 

Bob Dixson, Mayor, Greensburg, 

Kansas. 

Marilyn Murrell, Mayor, Arcadia, 

Oklahoma. 

Ronald K. Davis, Mayor, Prichard, 

Alabama. 

Adam Ortiz, Mayor, Edmonston, 

Maryland. 

Heather McTeer Hudson, Mayor, 

Greenville, Mississippi. 

Carolyn Peterson, Mayor, Ithaca, New 

York. 

Lisa A.Wong, Mayor, Fitchburg, 

Massachusetts. 

David W. Smith, Mayor, Newark, 

California. 

Tribal (Elected and Appointed) 

Steve Ortiz, Chairman Prairie Band 

Potawatomi Nation, Kansas. 

Aaron Miles, Manager at Nez Perce 

Tribe, Idaho. 

Commonwealth 

Evelyn Delereme Camacho, Mayor, 

Municipality of Vieques, Puerto Rico. 

County Executive 

Tom Hickner, County Executive, Bay 

County, Michigan. 

County Commissioners 

*Dave Somers, Councilor, Snohomish 

County, Washington. 

Robert Cope, Commissioner, Lemhi 

County, Idaho. 

Salud Carbajal, Supervisor, Santa 

Barbara County, California. 

Conservation Districts 

Jeffrey Tiberi, Director of Montana 

Association of Conservation Districts, 

Helena, Montana. 

City Councilmember 

Jill Duson, Councilor, Portland, 

Maine. 


jlentini on DSKJ8SOYB1PROD with NOTICES