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|PART IV                       
|SIGNATURES                    
|EXHIBIT INDEX                 
|Consent of Arthur Andersen LLP
|Employee Stock Purchase Plan  



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FORM 10-K/A-1

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

(Mark One)

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| |  | ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
EXCHANGE ACT OF 1934
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| |  | For the fiscal year ended December 31, 2000                                         

OR

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Commission File No. 000-30549

GENOMIC SOLUTIONS INC.
(Exact name of registrant as specified in its charter)

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|State of Delaware      |  | 38-3383038              
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|State of Incorporation |  | I.R.S. Employer I.D. No.

4355 Varsity Drive
Suite E
Ann Arbor, Michigan 48108
(734) 975-4800
(Address of principal executive offices and telephone number)

Securities Registered Pursuant to Section 12(b) of the Act:None

Securities Registered Pursuant to Section 12(g) of the Act:Common Stock, Par Value $.001 Per Share(See explanatory note)

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405
of Regulation S-K is not contained herein, and will not be contained, to the
best of Registrants knowledge, in definitive proxy or information statements
incorporated by reference in Part III of this Form 10-K or any amendment to
this Form 10-K.



Indicate by check mark whether the Registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
Registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days.

Yes       No

As of April 26, 2001, the aggregate market value of the Registrants common
stock held by non-affiliates of the Registrant was approximately $57,953,317,
determined in accordance with the highest price at which the stock was sold on
such date as reported by the Nasdaq National Market.

As of April 26, 2001, there were 24,207,057 shares of the Registrants common
stock issued and outstanding.





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EXPLANATORY NOTE: This Amendment No. 1 to the Registrants Annual Report on
Form 10-K for the fiscal year ended December 31, 2000 (the Form 10-K) is
filed to add certain exhibits under Part IV, Item 14. The Registrant has also
amended the cover page to reflect that as a result of the automatic conversion
of each share of the Registrants callable common stock into one share of the
Registrants common stock, the class of the Registrants securities registered
under Section 12(g) of the Act is common stock, par value $.001 per share.
This conversion is more fully described in the Registrants Amendment to Form
8-A filed April 19, 2001 and the Registrants Current Report on Form 8-K
filed on April 23, 2001.

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ITEM 14. EXHIBITS, FINANCIAL STATEMENT SCHEDULES AND REPORTS ON FORM 8-K:



|(3) | Exhibits: |  |   |                                                                                                               
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|    | 23.1      |  |  | Consent of Arthur Andersen LLP, Independent Public Accountants                                                
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|    | 99.1      |  |  | Information required by Form 11-K with respect to the Genomic Solutions Inc. 2000 Employee Stock Purchase Plan

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The undersigned registrant hereby amends the following items, financial
statements and exhibits of its Annual Report for its fiscal year ended December
31, 2000 on Form 10-K as set forth in the pages attached hereto:

To file as Exhibit 99.1 the Information, Financial Statements and Exhibits
required by Form 11-K for the Genomic Solutions Inc. 2000 Employee Stock Purchase
Plan and to update the cover page to reflect the conversion of the Registrants
callable common stock into common stock.

Pursuant to the requirements of Section 13 or 15(d) of the Security
Exchange Act of 1934, the Registrant has duly caused this Form 10-K/A-1 report
to be signed on its behalf by the undersigned, thereunto duly authorized.

Date: April 30, 2001

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| |  | GENOMIC SOLUTIONS INC.                                                                                                                              
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| |  | By: /s/ Jeffrey S. Williams                                                                                                                         
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| |  | Jeffrey S. Williams, President and
Chief Executive Officer                                                                                          
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| |  | By: /s/ Steven J. Richvalsky                                                                                                                        
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| |  | Steven J. Richvalsky, Chief
Financial Officer, Executive
Vice President and Treasurer
(Principle Financial Officer and
Principle Accounting Officer)

Pursuant to the requirements of the Securities Exchange Act of 1934, this
Annual Report on Form 10-K has been signed by the following persons on behalf
of the registrant and in the capacities and on the dates indicated.

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|Name                                        |  | Title                                           |  | Date          
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|/s/ Jeffrey S. Williams
Jeffrey S. Williams |  | President, Chief Executive
Officer and Director |  | April 27, 2001

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|                                                  |  |                                    |  |               
|------------------------------------------------- |  | ---------------------------------- |  | --------------
|Name                                              |  | Title                              |  | Date          
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|/s/ Robert G. Shepler
Robert G. Shepler           |  | Chairman of the Board of
Directors |  | April 27, 2001
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|/s/ J. Matthew Mackowski
J. Matthew Mackowski     |  | Director                           |  | April 27, 2001
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|/s/ Daniel J. Mitchell
Daniel J. Mitchell         |  | Director                           |  | April 27, 2001
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|/s/ Damion E. Wicker, M.D.
Damion E. Wicker, M.D. |  | Director                           |  | April 27, 2001

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|            |  |             |  |                                                                                                               
|----------- |  | ----------- |  | --------------------------------------------------------------------------------------------------------------
|Exhibit No. |  | Description
|            |  |            
|23.1        |  |            |  | Consent of Arthur Andersen LLP, Independent Public
Accountants                                                
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|99.1        |  |            |  | Information required by Form 11-K with respect to the
Genomic Solutions Inc. 2000 Employee Stock Purchase Plan

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