65234 Federal Register / Vol. 65, No. 211 / Tuesday, October 31, 2000 / Notices

ENVIRONMENTAL PROTECTION

AGENCY

[OPPTS–41051; FRL–6049–5]

Forty-Third Report of the TSCA

Interagency Testing Committee to the

Administrator; Receipt of Report and

Request for Comments

AGENCY: Environmental Protection

Agency (EPA).

ACTION: Notice.

SUMMARY: The Toxic Substances Control

Act (TSCA) Interagency Testing

Committee (ITC) transmitted its FortyThird Report to the Administrator of the

EPA on November 19, 1998. In the 43rd

Report, which is included with this

notice, the ITC revised the TSCA section

4(e) Priority Testing List by removing 9

High Production Volume Chemicals

(HPVCs), 7 alkylphenols, and 2

octylphenol ethoxylates. The ITC is also

asking EPA to promulgate a TSCA

section (d) reporting rule for 18

alkylphenols; 15 nonylphenol

ethoxylates; 3-amino-5-mercapto-1,2,4-

triazole; glycoluril; and methylal

recommended by the ITC for testing in

several previous ITC Reports. There are

no recommended, designated, or

recommended with intent-to-designate

chemicals or chemical groups in the 43rd

Report. EPA invites interested persons

to submit written comments on the

Report.

DATES: Comments, identified by docket

control number OPPTS–41051, must be

received on or before November 30,

2000.

ADDRESSES: Comments may be

submitted by mail, electronically, or in

person. Please follow the detailed

instructions for each method as

provided in Unit I. of the

SUPPLEMENTARY INFORMATION. To ensure

proper receipt by EPA, it is imperative

that you identify docket control number

OPPTS–41051 in the subject line on the

first page of your response.

FOR FURTHER INFORMATION CONTACT: For

general information contact: Barbara

Cunningham, Acting Director,

Environmental Assistance Division,

Office of Pollution Prevention and

Toxics (7408), Environmental Protection

Agency, 1200 Pennsylvania Ave., NW.,

Washington, DC 20460; telephone

number: (202) 554–1404; e-mail address:

TSCA-Hotline@epa.gov.

For technical information contact:

John D. Walker, ITC Executive Director

(7401), Environmental Protection

Agency, 1200 Pennsylvania Ave., NW.,

Washington, DC 20460; telephone

number: (202) 260–1825; fax: (202) 260–

7895; e-mail address:

walker.johnd@epa.gov.

SUPPLEMENTARY INFORMATION:

I. General Information

A. Does this Action Apply to Me?

This action is directed to the public

in general. It may, however, be of

particular interest to you if you

manufacture (defined by statute to

include import) any of the chemicals

listed and you may be identified by the

North American Industrial

Classification System (NAICS) codes

325 and 32411. Because this action is

directed to the general public and other

entities may also be interested, the

Agency has not attempted to describe all

the specific entities that may be

interested in this action. If you have any

questions regarding the applicability of

this action to a particular entity, consult

the person listed under FOR FURTHER

INFORMATION CONTACT.

B. How Can I Get Additional

Information, Including Copies of this

Document or Other Related Documents?

1. Electronically. You may obtain

electronic copies of this document, and

certain other related documents that

might be available electronically, from

the EPA Internet Home Page at http://

www.epa.gov/. To access this

document, on the Home Page select

‘‘Laws and Regulations,’’ ‘‘Regulations

and Proposed Rules,’’ and then look up

the entry for this document under the

‘‘Federal Register—Environmental

Documents.’’ You can also go directly to

the Federal Register listings at http://

www.epa.gov/fedrgstr/.

You may also access additional

information about the ITC and the TSCA

testing program through the web site for

the Office of Prevention, Pesticides and

Toxic Substances (OPPTS) at http://

www.epa.gov/internet/oppts/, or go

directly to the ITC Home Page at http:/

/www.epa.gov/opptintr/itc/.

2. In person. The Agency has

established an official record for this

action under docket control number

OPPTS–41051. The official record

consists of the documents specifically

referenced in this action, any public

comments received during an applicable

comment period, and other information

related to this action, including any

information claimed as Confidential

Business Information (CBI). This official

record includes the documents that are

physically located in the docket, as well

as the documents that are referenced in

those documents. The public version of

the official record does not include any

information claimed as CBI. The public

version of the official record, which

includes printed, paper versions of any

electronic comments submitted during

an applicable comment period, is

available for inspection in the TSCA

Nonconfidential Information Center,

North East Mall Rm. B–607, Waterside

Mall, 401 M St., SW., Washington, DC.

The Center is open from noon to 4 p.m.,

Monday through Friday, excluding legal

holidays. The telephone number for the

Center is (202) 260–7099.

C. How and to Whom Do I Submit

Comments?

You may submit comments through

the mail, in person, or electronically. To

ensure proper receipt by EPA, it is

imperative that you identify docket

control number OPPTS–41051 in the

subject line on the first page of your

response.

1. By mail. Submit your comments to:

Document Control Office (7407), Office

of Pollution Prevention and Toxics

(OPPT), Environmental Protection

Agency, 1200 Pennsylvania Ave., NW.,

Washington, DC 20460.

2. In person or by courier. Deliver

your comments to: OPPT Document

Control Office (DCO) in East Tower Rm.

G–099, Waterside Mall, 401 M St., SW.,

Washington, DC. The DCO is open from

8 a.m. to 4 p.m., Monday through

Friday, excluding legal holidays. The

telephone number for the DCO is (202)

260–7093.

3. Electronically. You may submit

your comments electronically by e-mail

to: oppt.ncic@epa.gov, or mail your

computer disk to the address identified

above. Do not submit any information

electronically that you consider to be

CBI. Electronic comments must be

submitted as an ASCII file avoiding the

use of special characters and any form

of encryption. Comments and data will

also be accepted on standard disks in

WordPerfect 6.1/8 or ASCII file format.

All comments in electronic form must

be identified by docket control number

OPPTS–41051. Electronic comments

may also be filed online at many Federal

Depository Libraries.

D. How Should I Handle CBI

Information That I Want to Submit to

the Agency?

Do not submit any information

electronically that you consider to be

CBI. You may claim information that

you submit to EPA in response to this

document as CBI by marking any part or

all of that information as CBI.

Information so marked will not be

disclosed except in accordance with

procedures set forth in 40 CFR part 2.

In addition to one complete version of

the comment that includes any

information claimed as CBI, a copy of

Federal Register / Vol. 65, No. 211 / Tuesday, October 31, 2000 / Notices 65235

the comment that does not contain the

information claimed as CBI must be

submitted for inclusion in the public

version of the official record.

Information not marked confidential

will be included in the public version

of the official record without prior

notice. If you have any questions about

CBI or the procedures for claiming CBI,

please consult the technical person

listed under FOR FURTHER INFORMATION

CONTACT.

E. What Should I Consider as I Prepare

My Comments for EPA?

We invite you to provide your views

and comments on the ITC’s 43rd Report.

You may find the following suggestions

helpful for preparing your comments:

1. Explain your views as clearly as

possible.

2. Describe any assumptions that you

used.

3. Provide copies of any technical

information and/or data you used that

support your views.

4. Provide specific examples to

illustrate your concerns.

5. Make sure to submit your

comments by the deadline in this

notice.

6. To ensure proper receipt by EPA,

be sure to identify the docket control

number OPPTS–41051 in the subject

line on the first page of your response.

You may also provide the name, date,

and Federal Register citation.

II. Background

The Toxic Substances Control Act

(TSCA) (15 U.S.C. 2601 et seq.)

authorizes the Administrator of the EPA

to promulgate regulations under section

4(a) requiring testing of chemicals and

chemical groups in order to develop

data relevant to determining the risks

that such chemicals and chemical

groups may present to health or the

environment. Section 4(e) of TSCA

established the ITC to recommend

chemicals and chemical groups to the

Administrator of the EPA for priority

testing consideration. Section 4(e) of

TSCA directs the ITC to revise the TSCA

section 4(e) Priority Testing List at least

every 6 months.

EPA has received the TSCA ITC’s

43rd Report to the Administrator. The

most recent revisions to the Priority

Testing List are included in the ITC’s

43rd Report. The Report was received

by the EPA Administrator on November

19, 1998, and is included in this notice.

The ITC revised the TSCA section 4(e)

Priority Testing List by removing 9

HPVCs that were recommended in the

36th Report (60 FR 42982, August 17,

1995) (FRL–4965–6) and 7 alkylphenols

and 2 octylphenol ethoxylates that were

recommended in the 37th Report (61 FR

4188, February 2, 1996) (FRL–4991–6).

The ITC is also asking EPA to

promulgate a TSCA section 8(d)

reporting rule for 15 nonylphenol

ethoxylates that were recommended in

the 39th Report (62 FR 8578, February

25, 1997) (FRL–5580–9), 18

alkylphenols that were recommended in

the 41st Report (63 FR 17658, April 8,

1998) (FRL–5773–5), and 3-amino-5-

mercapto-1,2,4-triazole; glycoluril; and

methylal that were recommended in the

42nd Report (63 FR 42553, August 7,

1998) (FRL–5797–8) to determine if

there are unpublished data to meet

previously determined U.S. Government

data needs.

1. Promulgation of a TSCA section

8(d) reporting rule. The ITC’s Voluntary

Information Submissions Innovative

Online Network (VISION) is accessible

through the world wide web (http://

www.epa.gov/opptintr/itc/vision.htm)

and is designed to promote more

efficient use of TSCA section 8

resources through submission of

electronic information. As part of

VISION, the Voluntary Information

Submission Policy clearly states that if

the ITC does not receive voluntary

electronic information submissions to

meet the data needs for recommended

chemicals, then it will ask the EPA to

promulgate a TSCA section 8(d)

reporting rule to determine if there are

unpublished studies to meet those data

needs. The EPA is being asked to

promulgate a TSCA section 8(d)

reporting rule for the chemicals

referenced in this unit, because studies

submitted to the VISION did not

adequately meet the data needs for those

chemicals. The ITC is requesting that

the EPA promulgate a TSCA section 8(d)

reporting rule to meet only those data

needs listed in certain previous ITC

Reports.

2. Data needs—i. Nonylphenol

ethoxylates and alkylphenols. Data

needs for 15 nonylphenol ethoxylates

recommended in the 39th ITC Report

and 18 alkylphenols recommended in

the 41st ITC Report are identical and are

listed in this unit as they were

expressed in the 41st ITC Report:

a. Fish and amphibian multigeneration reproductive effects data.

b. Avian acute toxicity data (oral

feeding and egg exposure studies).

c. Avian reproductive effects data.

d. Fish and wildlife studies data.

e. Bioaccumulation or bioavailability

data.

f. Health effects data, including

absorption, toxicokinetics, systemic

toxicity, endocrine disruption,

reproductive effects, and

carcinogenicity data.

ii. 3-Amino-5-mercapto-1,2,4-triazole.

Data needs for 3-amino-5-mercapto1,2,4-triazole are listed in this unit as

they were expressed in the 42nd ITC

Report: Health effects.

iii. Glycoluril. Data needs for

glycoluril are listed in this unit as they

were expressed in the 42nd Report:

Health effects.

iv. Methylal. Data needs for methylal

are listed in this unit as they were

expressed in the 42nd Report: Health

effects, especially, in vivo mammalian

metabolism and chronic effects.

3. Status of the Priority Testing List.

The TSCA section 4(e) Priority Testing

List as of November 1998 can be found

in Table 1 of the 43rd ITC Report which

is included in this notice.

List of Subjects

Environmental protection, Chemicals,

Hazardous substances.

Dated: October 24, 2000.

Charles M. Auer,

Director, Chemical Control Division, Office

of Pollution Prevention and Toxics.

Forty-Third Report of the TSCA

Interagency Testing Committee to the

Administrator, U.S. Environmental

Protection Agency

Table of Contents

Summary

I. Background

II. TSCA Section 8 Reporting

A. TSCA Section 8 Rules

B. ITC’s Use of TSCA Section 8 and ‘‘Other

Information’’

C. Promoting More Efficient Use of

Information Submission Resources

D. Request to Promulgate a TSCA Section

8(d) Rule

E. Chemicals for Which the ITC is

Requesting That EPA Promulgate a TSCA

Section 8(d) Rule

III. ITC’s Dialogue Group Activities During

This Reporting Period (May to November

1998)

IV. Revisions to the TSCA Section 4(e)

Priority Testing List

A. Summary Table of Changes

B. Chemicals Removed From the Priority

Testing List

V. TSCA Interagency Testing Committee

Summary

This is the 43rd Report of the TSCA

Interagency Testing Committee (ITC) to

the Administrator of the U.S.

Environmental Protection Agency

(EPA). In this Report, the ITC is revising

its TSCA section 4(e) Priority Testing

List by removing 9 High Production

Volume Chemicals (HPVCs), 7

alkylphenols, and 2 octylphenol

ethoxylates. In this Report, the ITC is

also asking EPA to promulgate a TSCA

section 8(d) Health and Safety Data

Reporting (HaSD) rule for 18

65236 Federal Register / Vol. 65, No. 211 / Tuesday, October 31, 2000 / Notices

alkylphenols, 15 nonylphenol

ethoxylates, 3-amino-5-mercapto-1,2,4-

triazole, glycoluril, and methylal to

determine if there are unpublished data

to meet previously determined U.S.

Government data needs. The revised

TSCA section 4(e) Priority Testing List

follows as Table 1.

TABLE 1.—THE TSCA SECTION 4(E) Priority Testing List (NOVEMBER 1998) 1

Report Date Chemical/Group Action

26 ......................... May 1990 ........................... 8 Isocyanates .................................................. Recommended with intent-to-designate

27 ......................... November 1990 ................. 62 Aldehydes .................................................. Recommended with intent-to-designate

28 ......................... May 1991 ........................... Chemicals with Low Confidence Reference

Dose (RfD).

Acetone

Thiophenol

Designated

30 ......................... May 1992 ........................... 5 Siloxanes ..................................................... Recommended

31 ......................... January 1993 ..................... 24 Chemicals with insufficient dermal absorption rate data.Designated

32 ......................... May 1993 ........................... 32 Chemicals with insufficient dermal absorption rate data.Designated

35 ......................... November 1994 ................. 24 Chemicals with insufficient dermal absorption rate data.Designated

37 ......................... November 1995 ................. 16 Alkylphenols and 3 alkylphenol

polyethoxylates.

Recommended

39 ......................... November 1996 ................. 15 Nonylphenol ethoxylates and 8

alkylphenol polyethoxylates.

Recommended

41 ......................... November 1997 ................. 18 Alkylphenols, 5 polyalkyphenols, and 6

alkylphenol polyethoxylates.

Recommended

42 ......................... May 1998 ........................... 3-Amino-5-mercapto-1,2,4-triazole ................. Recommended

42 ......................... May 1998 ........................... Glycoluril ......................................................... Recommended

42 ......................... May 1998 ........................... Methylal ........................................................... Recommended

42 ......................... May 1998 ........................... Ethyl silicate2 ................................................... Recommended

1 The Priority Testing List is available from the ITC’s web site (http://www.epa.gov/opptintr/itc). 2 Data requested through the ITC’s Voluntary Information Submissions Innovative Online Network (VISION) (see http://www.epa.gov/opptintr/

itc/vision.htm).

I. Background

The ITC was established by section

4(e) of the Toxic Substances Control Act

(TSCA) ‘‘to make recommendations to

the Administrator respecting the

chemical substances and mixtures to

which the Administrator should give

priority consideration for the

promulgation of a rule for testing under

section 4(a).... At least every six

months..., the Committee shall make

such revisions to the Priority Testing

List as it determines to be necessary and

transmit them to the Administrator

together with the Committee’s reasons

for the revisions’’ (Public Law 94–469,

90 Stat. 2003 et seq. (15 U.S.C. 2601 et

seq.)). Since its creation in 1976, the ITC

has submitted 42 semi-annual (May and

November) Reports to the EPA

Administrator transmitting the Priority

Testing List and its revisions. In 1989,

the ITC began recommending chemical

substances for information reporting,

screening, and testing to meet the data

needs of its member U.S. Government

organizations. ITC Reports are available

from http://www.epa.gov/opptintr/itc/

within a few days of submission to the

Administrator and from http://

www.epa.gov/fedrgstr/ after publication

in the Federal Register. The ITC meets

monthly and produces its revisions to

the List with administrative and

technical support from the ITC staff and

contract support provided by EPA. ITC

members and staff are listed at the end

of this Report.

II. TSCA Section 8 Reporting

A. TSCA Section 8 Rules

Following receipt of the ITC’s Report

by the EPA Administrator and addition

of chemicals to the Priority Testing List,

the EPA’s Office of Pollution Prevention

and Toxics (OPPT) promulgates TSCA

section 8(a) Preliminary Assessment

Information Reporting (PAIR) and TSCA

section 8(d) HaSD Reporting rules for

chemicals added to the Priority Testing

List. These rules require producers and

importers of chemicals recommended

by the ITC to submit production and

exposure reports under TSCA section

8(a) and producers, importers, and

processors of chemicals recommended

by the ITC to submit unpublished health

and safety studies under TSCA section

8(d). These rules are automatically

promulgated by OPPT unless requested

not to do so by the ITC.

B. ITC’s Use of TSCA Section 8 and

‘‘Other Information’’

The ITC reviews the TSCA section

8(a) PAIR reports, TSCA section 8(d)

HaSD studies, and ‘‘other information’’

that becomes available after the ITC

adds chemicals to the Priority Testing

List. ‘‘Other information’’ includes

TSCA section 4(a) and 4(d) studies,

TSCA section 8(c) submissions, TSCA

section 8(e) ‘‘substantial risk’’ notices,

‘‘For Your Information’’ (FYI)

submissions, ITC voluntary

submissions, unpublished data

submitted to U.S. Government

organizations represented on the ITC,

published papers, as well as use,

exposure, effects, and persistence data

that are voluntarily submitted to the ITC

by manufacturers, importers, processors,

and users of chemicals recommended by

the ITC. The ITC reviews this

information and determines if data

needs should be revised, if chemicals

should be removed from the Priority

Testing List or if recommendations

should be changed to designations.

C. Promoting More Efficient Use of

Information Submission Resources

The Voluntary Information

Submissions Innovative Online Network

(VISION) is accessible through the

world wide web (http://www.epa.gov/

opptintr/itc/vision.htm). VISION is the

vehicle that is used to promote more

efficient use of resources through

submission of electronic information.

VISION currently includes the

Voluntary Information Submissions

Policy (VISP), links to the TSCA

Electronic HaSD Reporting Form

(http://cyber22.dcoirm.epa.gov/oppt/

Federal Register / Vol. 65, No. 211 / Tuesday, October 31, 2000 / Notices 65237

tsca.nsf/HaSDForm?openform) and

instructions for the Form (http://

www.epa.gov/opptintr/itc/tscahlp.htm). The VISP provides examples

of data needed by ITC member U.S.

Government organizations, examples of

studies that should not be submitted,

the 60-, 90-, and 120-day milestones for

meeting the objectives of the VISP,

guidelines for using the TSCA

Electronic HaSD Reporting Form, and

instructions for electronically

submitting full studies. The TSCA

Electronic HaSD Reporting Form is used

to provide electronic information on ITC

and TSCA section 8(d) studies (to meet

data needs of the ITC member U.S.

Government organizations), FYI, and

TSCA section 8(e) studies, and studies

to meet the needs of the HPV Chemical

Challenge Program (http://

www.epa.gov/opptintr/chemtest/

hpv.htm).

D. Request to Promulgate a TSCA

Section 8(d) Rule

The ITC encourages producers,

importers, processors, and users of its

recommended chemicals to use VISION

to voluntarily provide electronic

information and establish a dialogue

with the ITC to discuss needed data. As

part of VISION, the VISP clearly states

that if the ITC does not receive

voluntary electronic information

submissions to meet its data needs, then

it will ask the EPA to promulgate a

TSCA section 8(d) HaSD rule to

determine if there are unpublished data

to meet those needs. As noted in Unit

2.C. of this Report, the TSCA Electronic

HaSD Reporting Form is used to provide

electronic information on TSCA section

8(d) studies. The ITC strongly

encourages those companies that must

respond to a TSCA section 8(d) rule to

provide only the data requested by the

ITC and to provide data by using the

TSCA Electronic HaSD Reporting Form.

At this time, the ITC is requesting that

the EPA promulgate a TSCA section 8(d)

rule for several chemicals with the

understanding that submissions that

were voluntarily provided as ITC

submissions, do not have to be resubmitted under the TSCA section 8(d)

HaSD rule. The ITC is requesting that

the EPA promulgate a TSCA section 8(d)

HaSD rule to meet only those data needs

listed in previous ITC Reports.

E. Chemicals for Which the ITC is

Requesting That EPA Promulgate a

TSCA Section 8(d) Rule

1. 39th and 41st Report chemicals.

The ITC considered structures and

annual production and importation

volumes for nonylphenol ethoxylates

and nonylphenol polyethoxylates

recommended in the 39th Report (62 FR

8578, February 25, 1997) (FRL–5580–9)

and for alkylphenols, polyalkylphenols,

and alkylphenol polyethoxylates

recommended in the 41st Report (63 FR

17658, April 9, 1998) (FRL–5773–5). In

addition, the ITC considered use and

health and safety data voluntarily

submitted to the ITC by the Chemical

Manufacturers Association (CMA)

Alkylphenols and Ethoxylates (AP&E)

Panel before VISION was developed,

health and safety data voluntarily

submitted through VISION as well as

TSCA section 8(d) health and safety

data submitted for structurally related

chemicals in the 37th Report (61 FR

4188, February 2, 1996) (FRL–4991–6).

After considering this information, and

determining that it was not adequate to

meet the data needs for these chemicals,

the ITC decided to ask EPA to

promulgate a TSCA section 8(d) HaSD

rule for the nonylphenol ethoxylates

recommended in the 39th Report and

the alkylphenols recommended in the

41st Report. These chemicals are listed

in Table 2.

2. 42nd Report chemicals. The ITC

sent its 42nd Report (63 FR 42554,

August 7, 1998) (FRL–5797–8) to

manufacturers of 3-amino-5-mercapto1,2,4-triazole, glycoluril, and methylal

and requested that they use VISION to

provide data to meet the U.S.

Government data needs described in the

42nd Report. Since no information to

meet these data needs was received, the

ITC is asking EPA to promulgate a TSCA

section 8(d) HaSD rule for these

chemicals to determine if there are

unpublished data to meet those needs.

The ITC also contacted the Silicones

Environmental Health and Safety

Council (SEHSC) about providing data

for ethyl silicate. The SEHSC agreed to

meet with the ITC to discuss data needs.

If needed data are not provided, the ITC

will consider asking EPA to promulgate

a TSCA section 8(d) HaSD rule for ethyl

silicate.

TABLE 2.—CHEMICALS FOR WHICH THE ITC IS REQUESTING THAT EPA PROMULGATE A TSCA SECTION 8(D) HASD RULE

CAS No. Chemical name ITC Report describing U.S.

Government data needs

. Pentylphenols

136–81–2 ....................... Phenol, 2-pentyl- ........................................................................................................ 41

3279–27–4 ..................... Phenol, 2-(1,1-dimethylpropyl)- .................................................................................. 41

25735–67–5 ................... Phenol, 4-sec-pentyl- ................................................................................................. 41

26401–74–1 ................... Phenol, 2-sec-pentyl- ................................................................................................. 41

. Hexylphenols

2446–69–7 ..................... Phenol, 4-hexyl- ......................................................................................................... 41

. Heptylphenols

1987–50–4 ..................... Phenol, 4-heptyl- ........................................................................................................ 41

72624–02–3 ................... Phenol, heptyl derivs. ................................................................................................. 41

84605–25–4 ................... Phenol, 1-methylhexyl derivs. .................................................................................... 41

. Octylphenols

140–66–9 ....................... Phenol, 4(1,1,3,3-tetramethylbutyl) ............................................................................ 41

71902–25–5 ................... Phenol, octenylated .................................................................................................... 41

. Nonylphenols

68081–86–7 ................... Phenol, nonyl derivs. .................................................................................................. 41

91672–41–2 ................... Phenol, 2-nonyl-, branched ........................................................................................ 41

. Decylphenols

27157–66–0 ................... Phenol, tetradecyl- ..................................................................................................... 41

65238 Federal Register / Vol. 65, No. 211 / Tuesday, October 31, 2000 / Notices

TABLE 2.—CHEMICALS FOR WHICH THE ITC IS REQUESTING THAT EPA PROMULGATE A TSCA SECTION 8(D) HASD

RULE—Continued

CAS No. Chemical name ITC Report describing U.S.

Government data needs

. Dodecylphenols

74499–35–7 ................... Phenol, (tetrapropenyl) derivs. ................................................................................... 41

. Tetradecylphenols

70682–80–3 ................... Phenol, tetradecyl- ..................................................................................................... 41

. Hexadecylphenols

2589–78–8 ..................... Phenol, hexadecyl ...................................................................................................... 41

25401–86–9 ................... Phenol, 2-hexadecyl- .................................................................................................. 41

. Other Alkylphenols

68784–24–7 ................... Phenol, C18-30-alkyl derivs. ...................................................................................... 41

. Nonylphenol Ethoxylates

7311–27–5 ..................... Ethanol, 2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]- ...................................... 39

20427–84–3 ................... Ethanol, 2-[2-(4-nonylphenoxy)ethoxy] ...................................................................... 39

20636–48–0 ................... 3,6,9,12-Tetraoxatetradecan-1-ol, 14-(4-nonylphenoxy) ............................................ 39

26264–02–8 ................... 3,6,9,12-Tetraoxatetradecan-1-ol, 14-(nonylphenoxy)- .............................................. 39

26571–11–9 ................... 3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-(nonylphenoxy)- .......................... 39

27176–93–8 ................... Ethanol, 2-[2-(nonylphenoxy)ethoxy]- ........................................................................ 39

27177–01–1 ................... 3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-(nonylphenoxy)- ...................................... 39

27177–05–5 ................... 3,6,9,12,15,18,21-Heptaoxatricosan-1-ol, 23-(nonylphenoxy) ................................... 39

27177–08–8 ................... 3,6,9,12,15,18,21,24,27-Nonaoxanonacosan-1-ol, 29-(nonylphenoxy)- .................... 39

27986–36–3 ................... Ethanol, 2-(nonylphenoxy)- ........................................................................................ 39

65455–72–3 ................... 3,6,9,12,15,18,21,24,27-Nonaoxanonacosan-1-ol, 29-(isononylphenoxy)- ............... 39

98113–10–1 ................... Nonoxynol-9 ............................................................................................................... 39

NA1 ................................ Nonoxynol-2 ............................................................................................................... 39

NA1 ................................ Nonoxynol-3 ............................................................................................................... 39

NA1 ................................ Nonoxynol-7 ............................................................................................................... 39

. Other Chemicals

109–87–5 ....................... Methylal ...................................................................................................................... 42

496–46–8 ....................... Glycoluril ..................................................................................................................... 42

16691–43–3 ................... 3-Amino-5-mercapto-1,2,4-triazole ............................................................................. 42

1Not available

III. ITC’s Dialogue Group Activities

During This Reporting Period (May to

November 1998)

The CMA–ITC AP&E Dialogue Group

was formed by the CMA’s AP&E Panel

and the ITC’s AP&E Subcommittee in

March 1996 following the submission of

the ITC’s 37th Report to the EPA

Administrator in November 1995. The

Group was created to facilitate the ITC’s

retrieval of information on uses,

exposures, and health and ecological

effects of alkylphenols and alkylphenol

ethoxylates, and the Panel’s

understanding of data needed by the

U.S. Government organizations

represented on the Subcommittee. Since

the creation of this Dialogue Group,

numerous activities have occurred: See

the ITC’s 38th Report (61 FR 39832, July

30, 1996) (FRL–5379–2); 39th Report;

40th Report (62 FR 30580, June 4, 1997)

(FRL–5718–3); 41st Report, and 42nd

Report.

After the 42nd Report was delivered

to the EPA Administrator, some

members of the CMA’s AP&E Panel

formed the APE Research Council

(APERC). The APERC-ITC AP&E

Dialogue Group met twice during this

reporting period. On August 12 and

October 15, 1998, the Dialogue Group

met to discuss:

1. Status of TSCA section 8(a) PAIR

and TSCA section 8(d) rules for the 39th

and 41st ITC Reports.

2. Number and type of studies on

alkylphenols and alkylphenol

ethoxylates sent to VISION.

3. Status of research related to U.S.

Government data needs for alkylphenols

and alkylphenol ethoxylates (e.g.,

multigeneration fish studies to

determine offspring reproductive

capabilities).

4. Progress and results of ongoing

environmental and toxicological studies

being conducted or sponsored by

chemical manufacturers on the Council,

(e.g., mammalian in vitro and in vivo

toxicology, mammalian

pharmacokinetic, biodegradation,

aquatic toxicity, and avian acute toxicity

studies).

5. Organization for Economic

Cooperation and Development (OECD)

Screening Information Data Set (SIDS)

dossiers on nonylphenol and

nonylphenol ethoxylates.

6. Alkylphenols that may be removed

from the Priority Testing List.

7. Alkylphenols and nonylphenol

ethoxylates being considered for

Quantitative Structure Activity

Relationship (QSAR) studies.

IV. Revisions to the TSCA Section 4(e)

Priority Testing List

A. Summary Table of Changes

Revisions to the TSCA section 4(e)

Priority Testing List are summarized in

Table 3.

Federal Register / Vol. 65, No. 211 / Tuesday, October 31, 2000 / Notices 65239

TABLE 3.—REVISIONS TO THE TSCA SECTION 4(E) Priority Testing List

CAS No. Chemical name Action Date

Remove November 1998

........................ HPVCs ..................................................

80–51–3 ............. p,p’-Oxybis(benzenesulfonylhydrazide) .................... do. do.

81–84–5 ............. Naphthalenedicarboxylic anhydride ......................... do. do.

99–54–7 ............. 3,4-Dichloronitrobenzene ......................................... do. do.

100–29–8 ........... 4-Ethoxynitrobenzene ............................................... do. do.

119–33–5 ........... 4-Methyl-2-nitrophenol .............................................. do. do.

121–60–8 ........... 4-(Acetylamino) benzenesulfonyl chloride ............... do. do.

626–17–5 ........... 1,3-Dicyanobenzene ................................................. do. do.

929–06–6 ........... 2-(2-Aminoethoxy) ethanol ....................................... do. do.

3089–11–0 ......... Hexa(methoxymethyl) melamine .............................. do. do.

Butylphenols

3180–09–4 ......... 2-Butylphenol ............................................................ do. do.

27178–34–3 ....... tert-Butylphenol mixed isomers ................................ do. do.

........................ Pentylphenols

94–06–4 ............. 4-(1-Methylbutyl)phenol ............................................ do. do.

Octylphenols

949–13–3 ........... 2-Octylphenol ........................................................... do. do.

27985–70–2 ....... (1-Methylheptyl)phenol ............................................. do. do.

........................ Nonylphenols

11066–49–2 ....... Isononylphenol (mixed isomers) .............................. do. do.

17404–66–9 ....... 4-(1-Methyloctyl)phenol ............................................ do. do.

........................ Octylphenol Ethoxylates

2315–66–4 ......... Decaethylene glycol 4-isooctylphenyl ether ............. do. do.

2497–58–7 ......... Hexaethylene glycol 4-isooctylphenyl ether ............. do. do.

B. Chemicals Removed From the Priority

Testing List

1. HPVCs—a. Rationale. The ITC is

removing 9 HPVCs (Table 3) from the

Priority Testing List because:

i. EPA, CMA, and the Environmental

Defense Fund have agreed, that by the

year 2003, data will be provided or

developed for about 3,000 HPVCs

produced or imported into the United

States.

ii. The 3,000 HPVCs includes the 9

HPVCs on the Priority Testing List.

iii. At this time, there are no specific

U.S. Government data needs for these

chemicals that would not be met by the

HPV Chemical Challenge Program.

b. Supporting information. HPVCs are

chemicals with annual domestic

production or importation volumes

greater than 1 million pounds.

Information on ITC’s review of HPVCs

is contained in Reports 27th (56 FR

9534, March 6, 1991) (FRL–3845–3),

35th (59 FR 67596, December 29, 1994)

(FRL–4923–2), 36th (60 FR 42982,

August 17, 1995) (FRL–4965–6), 37th,

38th, and 40th.

The ‘‘Screening Information Data Set

(SIDS) Manual of the OECD Programme

on the Co-operative Investigation of

High Production Volume Chemicals,’’

provides test guidance for developing

data for HPVCs. The basic screening

endpoints are listed in section 2.2 (page

2) of this Manual (the ‘‘SIDS Manual;’’

available at http://www.epa.gov/

opptintr/sids/sidsman.htm).

2. Alkylphenols and alkylphenol

ethoxylates—a. Rationale. The ITC is

removing 2 butylphenols, 1

pentylphenol, 2 octylphenols, 2

nonylphenols, and 2 octylphenol

ethoxylates (Table 3) from the Priority

Testing List because no domestic

production or importation volumes

were reported to the EPA in response to

1986, 1990, and 1994 Information

Update Rules (indicating that volumes

were less than 10,000 pounds per site in

1985, 1989, and 1993), no domestic

production or importation volumes

were reported to the EPA in response to

the February 28, 1996, PAIR rule

(indicating that volumes were less than

1,000 pounds per site in 1995), no TSCA

section 8(d) studies were submitted to

the EPA in response to the February 28,

1996, HaSD rule and because no TSCA

section 8(e), FYI, or ITC studies were

available for these chemicals as of

September 1998.

b. Supporting information.

Information on the ITC’s review of

alkylphenols and alkylphenol

ethoxylates is contained in Reports 37,

38, 39, 40, and 41. The ITC reviewed

use and health and safety data

voluntarily submitted to the ITC by the

CMA–ITC AP&E Dialogue Group before

VISION was developed and health and

safety data voluntarily submitted

through VISION.

V. TSCA Interagency Testing

Committee

Statutory Organizations and Their

Representatives

Council on Environmental Quality

Brad Campbell, Member

Department of Commerce

National Institute of Standards and

Technology

Malcolm W. Chase, Member

Barbara C. Levin, Alternate

National Oceanographic and

Atmospheric Administration

Nancy Foster, Member

Teri Rowles, Alternate

Richard S. Artz, Alternate

Environmental Protection Agency

Paul Campanella, Member

David R. Williams, Alternate

National Cancer Institute

Victor Fung, Member, Chair

Harry Seifried, Alternate

National Institute of Environmental

Health Sciences

William Eastin, Member, Vice Chair

H.B. Matthews, Alternate

National Institute for Occupational

Safety and Health

Albert E. Munson, Member

Christine Sofge, Alternate

National Science Foundation

A. Frederick Thompson, Member

Joseph Reed, Alternate

Occupational Safety and Health

Administration

Lyn Penniman, Member

Val H. Schaeffer, Alternate

Liaison Organizations and Their

Representatives

Agency for Toxic Substances and

Disease Registry

William Cibulas, Member

Consumer Product Safety Commission

Jacqueline Ferrante, Member

Department of Agriculture

65240 Federal Register / Vol. 65, No. 211 / Tuesday, October 31, 2000 / Notices

;Clifford P. Rice, Member

Department of the Interior

Barnett A. Rattner, Member

Food and Drug Administration

Edwin J. Matthews, Member

Raju Kammula, Alternate

National Library of Medicine

Vera W. Hudson, Member

National Toxicology Program

NIEHS, FDA, and NIOSH Members

Counsel

Scott Sherlock, OPPT, EPA

Technical Support Contractor 

Syracuse Research Corporation

ITC Staff

John D. Walker, Executive Director

Norma S. L. Williams, Executive

Assistant

TSCA Interagency Testing Committee,

Office of Pollution Prevention and

Toxics (7401), Environmental Protection

Agency, Ariel Rios Bldg., 1200

Pennsylvania Ave., NW., Washington,

DC 20460; telephone: (202) 260–1825;

fax: (202) 260–7895; e-mail address:

williams.norma@epa.gov; url: http://

www.epa.gov/opptintr/itc.

[FR Doc. 00–27926 Filed 10–30–00; 8:45 am]

BILLING CODE 6560–50–F