Initial to indicate certification as to information on this page

(full text of certification is on page one).

Date

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. 

Use additional sheet(s) if necessary.

2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product

Registration

5. I wish to cancel

this product 

registration 

voluntarily

6. Generic Data 7. Product Specific Data

6a. I am claiming a Generic Data 

Exemption because I obtain the 

active ingredient from the source 

EPA registration number listed 

below.

6b. I agree to satisfy Generic Data

Requirements as indicated on the 

attached form entitled 

"Requirements Status and 

Registrant's Response."

7a. My product is an MUP and I 

agree to satisfy the MUP 

requirement on the attached form

entitled "Requirements Status and

Registrant's Response."

7b. My product is an EUP and I 

agree to satisfy the EUP 

requirement on the attached form 

entitled "Requirements Status and 

Registrant's Response."

OMB Approval 2070-0174

EPA FORM 6300-4

1. Company Name and Address

2055 - Bis(trichloromethyl) sulfone

Chemical # and Name: 035601

Bis(trichloromethyl) sulfone

GENERIC

ID # GDCI-035601-1334

United States Environmental Protection Agency

Washington, D.C. 20460

DATA CALL-IN RESPONSE

Page of 1 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

Signature and Title of Company's Authorized Representative ______________________________________________________

10. Name of Company

9. Date

11. Phone Number
Initial to indicate certification as to information on this page (full text of certification is on page one) 

13. Phone Number

10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any 

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

12. Name of Company

11. Date

OMB Approval 2070-0174 

EPA FORM 6300-3

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

Applicator Exposure Data Requirements (Conventional 

Chemical)

Post-Application Exposure Data Requirements (Conventional 

Chemical)

875.1200

875.1700

875.2800

835.1110

835.3110

835.3220

835.3240

Dermal exposure--Indoor

Product Use Information

Description of human activity

Activated sludge sorption isotherm

Ready biodegradability

Porous pot test

Simulation Test-Aerobic Sewage Treatment-Activated

Sludge

2055 - Bis(trichloromethyl) sulfone

Chemical # and Name: 035601

Bis(trichloromethyl) sulfone

GENERIC

ID # GDCI-035601-1334

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

TGAI

TGAI

TGAI

Degr; TGAI

Degr; TGAI

Degr; TGAI

Degr; TGAI

24

12

12

24

24

24

24

Page 1 of 

(1, 3)

(11, 20)

(11, 16)

(11, 19)

(11, 18)

N

N

N

N

N

N

N

4
OMB Approval 2070-0174 

EPA FORM 6300-3

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

835.3280

850.1010

850.1035

850.1055

850.1075

850.1300

850.1350

850.1400

850.3300

Simulation Tests to Assess the Biodegradability of 

Chemicals

Aquatic invertebrate acute toxicity, test, freshwater 

daphnids

Mysid acute toxicity test

Bivalve acute toxicity test (embryo larval)

Fish acute toxicity test, freshwater and marine

Daphnid chronic toxicity test

Mysid chronic toxicity test

Fish early-life stage toxicity test

Modified Activated Sludge, Respiration Inhibition Test

2055 - Bis(trichloromethyl) sulfone

Chemical # and Name: 035601

Bis(trichloromethyl) sulfone

GENERIC

ID # GDCI-035601-1334

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Degr; TGAI

Degr; TGAI

Degr; TGAI

DEGR

Degr; TGAI

Degr; TGAI

DEGR

Degr; TGAI

Degr; TGAI

24

24

24

24

24

24

24

24

24

Page 2 of 

(11, 17)

(11)

(11)

(10)

(7)

(11)

(10)

(9)

(11, 15)

N

N

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N

N

N

N

N

N

4
OMB Approval 2070-0174 

EPA FORM 6300-3

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

850.4225

850.4400

850.4500

850.4550

870.3465

870.3800

870.4100

870.4200

870.7485

Seedling emergence, Tier II

Aquatic plant toxicity test using Lemna spp. Tiers I 

and II

Algal Toxicity

Cyanobacteria (Anabaena flos-aquae) Toxicity

90-day inhalation toxicity

Reproduction and fertility effects

Chronic toxicity

Carcinogenicity

Metabolism and pharmacokinetics

2055 - Bis(trichloromethyl) sulfone

Chemical # and Name: 035601

Bis(trichloromethyl) sulfone

GENERIC

ID # GDCI-035601-1334

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

DEGR

Degr; TGAI

Degr; TGAI

Degr; TGAI

TGAI

TGAI

TGAI

TGAI

TGAI

24

24

24

24

24

48

48

48

24

Page 3 of 

(10, 13)

(11)

(8, 14)

(8, 14)

(6)

N

N

N

N

N

N

N

N

N

4
Date

OMB Approval 2070-0174 

EPA FORM 6300-3

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

875.1100

875.1300

875.1400

875.2300

875.2500

875.2700

SS-Migration

Dermal exposure--outdoor

Inhalation exposure--outdoor

Inhalation exposure--indoor

Indoor surface residue dissipation

Inhalation exposure

Product Use Information

Migration studies

2055 - Bis(trichloromethyl) sulfone

Chemical # and Name: 035601

Bis(trichloromethyl) sulfone

GENERIC

ID # GDCI-035601-1334

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

Z,Y,X

TGAI

TGAI

TGAI

TGAI

TGAI

TGAI

TGAI

24

24

24

24

24

12

24

Page 4 of 

(1, 2)

(1, 5)

(1, 4)

(22, 23)

(21)

(12)

N

N

N

Y

N

N

Y

4
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

2055 - Bis(trichloromethyl) sulfone

GDCI-035601-1334

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

Study is needed for the following scenarios: (1) Open-pour loading, except for instances where the label requires a closed loading and delivery system to be used; (2) painting with a 

brush/roller; (3) airless sprayer.

Results from this outdoor dermal exposure study may be used to fulfill the requirement for a dermal indoor exposure study (875.1200) or visa versa.

Results from this indoor dermal exposure study may be used to fulfill the requirement for an outdoor dermal exposure study (875.1100) or visa versa.

Results from an inhalation outdoor exposure study (875.1300) may satisfy this data requirement for an inhalation indoor exposure study or visa versa.

Results from an inhalation indoor exposure study (875.1400) may satisfy this data requirement for an inhalation outdoor exposure study or visa versa.

Results from a multi-generation (EPA guideline 870.3800) or an extended one-generation reproductive and fertility effects study using OECD Test Guideline 443 (http://www.oecdilibrary.org/environment/test-no-443-extended-one-generation-reproductive-toxicity-study_9789264185371-en) will satisfy this requirement.

Results for studies conducted with the TGAI for both (i) coldwater and (ii) warmwater species; as well as results for a study conducted with the major degradate, pentachlorodimethylsulfone, 

for (iii) the most TGAI-sensitive species, must be submitted to satisfy this requirement.

Results for studies conducted with the TGAI for (i) the freshwater green alga, Selenastrum capricornutum, (ii) the freshwater diatom, Navicula pelliculosa, (iii) the marine diatom, Skeletonema 

costatum, and (iv) the cyanobacteria species Anabaena flos-aquae as well as results for a study with the major degradate, pentachlorodimethylsulfone, and (v) the most TGAI-sensitive 

species, must be submitted to satisfy this requirement.

Results for studies conducted using the most TGAI-sensitive species with both the TGAI and the major degradate, pentachlorodimethylsulfone, must be submitted to satisfy this requirement.

Results for studies conducted using the major degradate, pentachlorodimethylsulfone, must be submitted to satisfy this requirement.

Results for studies conducted using both the TGAI and the major degradate, pentachlorodimethylsulfone, must be submitted to satisfy this requirement.

Migration of BTS from paper packaging to the food contents is likely to occur; therefore, registrants are required to conduct a food migration study. Registrants are required to submit a protocol 

for EPA review prior to initiating the study. A waiver may be requested if a screening level default of 100% of the residues do not trigger risk concerns.

In a Federal Register Notice dated June 27, 2012, test guidelines 850.4100 and 850.4225 were merged and harmonized into OCSPP 850.4100. See "Final Test Guidelines; OCSPP 850 Series; 

Notice of Availability" 77 FR 38282, June 27, 2012. http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0154-0028.

In a Federal Register Notice dated June 27, 2012, EPA split the Public Draft OPPTS 850.5400 test guideline into two test guidelines: OCSPP 850.4500 and OCSPP 850.4550. See Final Test 

Guidelines; OCSPP 850 Series; Notice of Availability 77 FR 38282, June 27, 2012. http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0154-0028.

EPA published draft guidance under guideline 850.6800 and has since published final guidance for this study under guideline 850.3300: http://www.regulations.gov/#!documentDetail;D=EPA-HQOPPT-2009-0154-0021.

Case # and Name:

DCI Number:

Page: 1 of

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. 

These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement.

Use Categories Key:

X - Materials preservatives

Y - Industrial processes and water systems - 

once through 

Z - Industrial processes and water systems - not 

once through

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

2055 - Bis(trichloromethyl) sulfone

GDCI-035601-1334

16

17

18

19

20

21

22

23

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

OECD Test Guideline 209 can also be used as guidance for this study, available online at http://www.oecd-ilibrary.org/content/book/9789264070080-en.

The results of the Activated Sludge Respiration Inhibition Test (ASRI), GLN 850.3300, will determine which of the four biodegradation tests is/are required. If the ASRI test EC50 is less than or 

equal to 20 mg/L, then either the (i) Biodegradation in Activated Sludge Study, GLN 835.3280 or (ii) Simulation Test - Aerobic Sewage Treatment: A. Activated Sludge Units, GLN 835.3240, or (iii) 

the Porous Pot Test, GLN 835.3220 is required. If the ASRI test EC50 is greater than 20 mg/L, then the registrant must conduct either: (i) Ready Biodegradability or (ii) a) Biodegradation in 

Activated Sludge or b) Simulation Test - Aerobic Sewage Treatment: A. Activated Sludge Units or c) the Porous Pot Test. If the Ready Biodegradability study is conducted and passes, then no 

further testing is required. If, however, the antimicrobial fails the Ready Biodegradability study, then either the (i) Simulation tests to assess the biodegradability of chemicals discharged in 

wastewater, (ii) the Simulation Test Aerobic Sewage Treatment A. Activated Sludge Units, or (iii) the Porous Pot Test.a) Biodegradation in Activated Sludge or b) Simulation Test - Aerobic 

Sewage Treatment: A. Activated Sludge Units, or c) the Porous Pot study is required.

EPA has published final guidelines for biodegradation studies, the required biodegradation study for ADAO is based on results of an Activated Sludge Respiration Inhibition test.

EPA has a published final guideline for this study: http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0152-0036. The biodegradation study required is based on results of an 

Activated Sludge Respiration Inhibition test.

EPA has a published final guideline for this study: http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0152-0034. The required biodegradation study is based on results of an 

Activated Sludge Respiration Inhibition test.

EPA has a published final guideline for this study: http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0152-0024. The required biodegradation study is based on results of an 

Activated Sludge Respiration Inhibition test.

EPA has a published final guideline for this study: http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0152-0003.

Based on the vapor pressure (IE-3 mmHg), a post-application inhalation exposure study (e.g. air chamber testing) is needed for the paint use.

An indoor surface residue study is required for the plastic use, if the plastic is used to manufacture plastic toys. A waiver may be requested if a screening level default of 100% of the residues 

do not trigger risk concerns.

A protocol must be submitted for review and approval prior to testing.

Case # and Name:

DCI Number:

Page: 2 of 2
United States Environmental Protection Agency 

Washington, D.C. 20460

LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE

Case # and Name: 2055 - Bis(trichloromethyl) sulfone

Page: 1 of 1

39967

74655

LANXESS CORPORATION

SOLENIS LLC

Co. Nr. Company Name Agent For Company

HERCULES INCORPORATED

111 RIDC PARK WEST DRIVE

7910 BAYMEADOWS WAY, SUITE 100

Address City ZIP

PITTSBURGH

JACKSONVILLE

152751112

32256 

OMB Approval 2070-0174

State

PA

FL

 DCI Number: GDCI-035601-1334