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|   | 1. | The Company’s Annual Report on Form 10-K for the year ended December 31, 2018, to which this Certification is attached as                Exhibit 32.1 (the “Periodic Report”), fully complies with the requirements of Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934, as amended, and |
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|   | 2. | The information contained in the Periodic Report fairly presents, in all material respects, the financial condition and results of operations of                the Company. |
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| /s/    Dolev Rafaeli                                              |   | /s/   Matthew C. Hill                 |
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| Dolev Rafaeli                                                                                                                                                                                                                                                             |   | Matthew C. Hill                                                                                        |
| President & Chief Executive Officer                                                                                                                                                                                                                         |   | Chief Financial Officer                                                                                |
| (1) | This certification accompanies the Annual Report on Form 10-K to which it relates, is not deemed filed with the Securities                and Exchange Commission and is not to be incorporated by reference into any filing of STRATA Skin Sciences, Inc. under the Securities Act of 1933, as amended, or the Exchange Act (whether made before or after the date of the Form 10-K),                irrespective of any general incorporation language contained in such filing. A signed original of this written statement required by Section 906 of the Sarbanes-Oxley Act of 2002 has been provided to STRATA Skin Sciences, Inc. and will be                retained by STRATA Skin Sciences, Inc. and furnished to the Securities and Exchange Commission or its staff upon request. |
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