---

MATERIALS TRANSFER AGREEMENT

THIS AGREEMENT dated 7 December, 2007 is made by and between
UPSTREAM BIOSCIENCES INC.(Upstream) and PROVINCIAL LAB FOR
PUBLIC HEALTH (ProvLabs) represented by Dr. Stephanie Yanow
(collectively, the Scientists).

Upstream hereby agrees to provide ProvLabs with certain the
materials and know-how listed in Schedule A hereto (collectively, the
Materials) for use in connection with the research activities described
in Schedule A hereto (Research) on the following terms and
conditions:

|1. | Scientists.The Research will be conducted by the
      Scientists in accordance with the terms of the Services Agreement between
      Upstream and ProvLabs dated 7 December, 2007 (the Services
      Agreement).                                                                                                                 
|-- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|   |                                                                                                                                                                                                                                                                                                                                       
|2. | Proprietary Rights.The Materials are proprietary
      to Upstream. Upstream will be free, in its sole discretion, to distribute
      the Materials to others and to use them for its own purposes. Neither
      ProvLabs nor any Scientist will have any rights in any of the Materials
      except as provided in this Agreement.
|   |                                                                                                                                                                                                                                                                                                                                       
|3. | Restrictions on Use.                                                                                                                                                                                                                                                                                                                  
|   |                                                                                                                                                                                                                                                                                                                                       
|   | (a)                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                       
|   | (b)                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                       
|4. | Limited License.                                                                                                                                                                                                                                                                                                                      
|   |                                                                                                                                                                                                                                                                                                                                       
|   | (a)                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                       
|   | (b)                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                       
|   | (c)                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                       
|   | (d)                                                                                                                                                                                                                                                                                                                                   

---

- 2 -

|5. | Non-Disclosure.                                                                                                                                                                                                                                                                                                                                                                                       
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   | (a)                                                                                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   | (b)                                                                                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   | (c)                                                                                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|6. | Storage.Without in any way limiting its
      obligations under Section 5, ProvLabs must retain all Information (defined
      below) and Materials in a secure place with access thereto limited to
      those persons who are specifically authorized to have access under this
      Agreement.                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|7. | Exceptions.ProvLabs will not have any obligations
      with respect to any Information disclosed by ProvLabs that:                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   | (a)                                                                                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   | (b)                                                                                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   | (c)                                                                                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|   | (d)                                                                                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|8. | Duty to Inform.If ProvLabs becomes aware or has
      knowledge of any unauthorized use or disclosure of any Information, then
      it must promptly notify Upstream of such unauthorized use or disclosure
      and take all reasonable steps to assist Upstream in attempting to minimize
      any potential or actual damages or losses that may result from such
      unauthorized disclosure.
|   |                                                                                                                                                                                                                                                                                                                                                                                                       
|9. | Return or Destruction of Materials and Information.Immediately upon request from Upstream or completion of the Research,
      whichever is sooner, ProvLabs must:                                                                                                                                                                                                                                    

---

- 3 -

|    | (a)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 | return all unused Materials to Upsteam; and                                                                                                                                                                                                  
|--- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                                              
|    | (b)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 | destroy or at Upstreams option, return to Upstream, any
      remaining Materials and return all of the Information, including all
      reproductions and copies thereof and delete all references thereto stored
      in electronic form.
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                                              
|10. | Reporting.ProvLabs will disclose to Upstream, in
      confidence, all results of the Research and any other evaluation and
      analysis of the Materials that ProvLabs or the Scientists perform in order
      to effectively carry out ProvLabss obligations under this Agreement.
      Recipient further agrees to promptly disclose the results of the Research
      and its other evaluation and analysis to Upstream on an ongoing basis
      under this Agreement and to deliver a final written report summarizing
      data generated during the Research and its other evaluation and analysis
      to Upstream within 30 days following completion of the Research.                                                            
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                                              
|11. | No Warranty.The Materials are experimental in
      nature and they are provided ON AN AS-IS BASIS WITHOUT WARRANTY OR
      CONDITION OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING ANY WARRANTY OR
      CONDITION OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. UPSTREAM
      MAKES NO REPRESENTATION OR WARRANTY THAT THE USE OF THE MATERIALS WILL NOT
      INFRINGE ANY PATENT OR OTHER PROPRIETARY RIGHT OF A THIRD PARTY.                                                                                                                                                                                                                                                                                                       
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                                              
|12. | Limitation on Liability. In no event will Upstream
      be liable for loss, claim, damage or liability of any kind resulting from
      or relating to the use of the Materials by ProvLabs or the Scientists,
      whether resulting from the Research or the use, handling or storage of the
      Material, or otherwise.                                                                                                                                                                                                                                                                                                                                                                                                                     
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                                              
|13. | Applicable Law.ProvLabs and the Scientists will
      use the Materials in compliance with all laws, governmental regulations
      and guidelines applicable to the Materials and the Research.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                                              
|14. | No Assignment by ProvLabs.ProvLabs has no right
      to assign or transfer all or any part of this Agreement, whether by
      operation of law or otherwise, without the prior written consent of
      Upstream.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                                              
|15. | Governing Law.This Agreement will be governed by
      and construed in accordance with the laws of the Province of British
      Columbia and the federal laws of Canada applicable therein, without regard
      to conflict of laws. Each party hereby irrevocably submits to the
      exclusive jurisdiction of the courts of British Columbia with respect to
      any recourse that it may want to exercise relating to the interpretation
      or enforcement of any provisions of this Agreement, except that either
      party will have the right to seek injunctive relief in any court of
      competent jurisdiction.                                                                                                            
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                                              
|16. | Successors; Number.This Agreement will be binding
      upon and inure to the benefit of the parties and their respective
      successors and permitted assigns and will be read with all changes in
      number and gender as may be required by the context.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                                              
|17. | Survival.No termination of this Agreement will
      affect the rights or obligations of either party that have accrued prior
      to the effective date of such termination. The provisions of Sections 2,
      3, 5, 8, 9, 11, 12 and 15 and of this Section will survive termination of
      this Agreement.                                                                                                                                                                                                                                                                                                                                                                                                                                 
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                                              
|18. | Counterpart.This Agreement may be executed in
      counterpart and such counterparts together will constitute a single
      instrument. Delivery of an executed counterpart of this Agreement by
      electronic means, including by facsimile transmission or by electronic
      delivery in portable document format (.pdf), will be equally effective
      as delivery of a manually executed counterpart hereof. The parties
      acknowledge and agree that in any legal proceedings between them
      respecting or in any way relating to this Agreement, each waives the right
      to raise any defence based on the execution hereof in counterparts or the
      delivery of such executed counterparts by electronic
  means.

---

- 4 -

IN WITNESS WHEREOF, the parties have signed this Agreement with
effect from the date first set forth on page one.

|Provincial Lab for Public
      Health |                      | Upstream Biosciences Inc.      
|-------------------------------------- | -------------------- | -------------------------------
|8440 112th Street,                     |                      | Suite 100 - 570 West 7th Avenue
|Edmonton, AB T6E 2G5                   |                      | Vancouver, BC V5Z 4S6          
|                                       |                      |                                
|                                       |                      |                                
|                                       |                      |                                
|                                       |                      |                                
|                                       |                      |                                
|Per:                                   |                      |                                
|                                       | Authorized Signatory |                                
|                                       |                      |                                
|                                       | Dr. Stephanie Yanow  |                                
|                                       |                      |                                

---

SCHEDULE A

MATERIALS

<>

---

SCHEDULE B

DESCRIPTION OF RESEARCH

The Research consists of those services described in Schedule A
 Test Specification and Requirements, dated October 23, 2007, to the Services
Agreement.

---