Initial to indicate certification as to information on this page

(full text of certification is on page one).

Date

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. 

Use additional sheet(s) if necessary.

2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product 

Registration

5. I wish to cancel 

this product 

registration 

voluntarily

6. Generic Data 7. Product Specific Data

6a. I am claiming a Generic Data 

Exemption because I obtain the 

active ingredient from the source 

EPA registration number listed 

below.

6b. I agree to satisfy Generic Data

Requirements as indicated on the 

attached form entitled 

"Requirements Status and 

Registrant's Response."

7a. My product is an MUP and I 

agree to satisfy the MUP 

requirement on the attached form

entitled "Requirements Status and

Registrant's Response."

7b. My product is an EUP and I 

agree to satisfy the EUP 

requirement on the attached form 

entitled "Requirements Status and 

Registrant's Response."

OMB Approval 2070-0174

1. Company Name and Address

 

N/A - Pyridaben 

Chemical # and Name: 129105

Pyridaben 

17-Nov-2011

GENERIC

ID # GDCI-129105-855

United States Environmental Protection Agency

Washington, D.C. 20460

DATA CALL-IN RESPONSE

Page of 1 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

Signature and Title of Company's Authorized Representative ______________________________________________________

10. Name of Company

N/A N/A

9. Date

11. Phone Number 
Initial to indicate certification as to information on this page (full text of certification is on page one) 

13. Phone Number

10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any 

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

12. Name of Company

11. Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

 

Environmental Fate Data Requirements (Conventional 

Chemical)

Nontarget Plant Protection Data Requirements (Conventional 

Chemical)

835.4100

835.4300

835.4400

835.6100

835.6200

850.4100

850.4150

850.4400

Aerobic soil metabolism

Aerobic aquatic metabolism

Anaerobic aquatic metabolism

Terrestrial field dissipation

Aquatic field dissipation

Terrestrial Plant Toxicity (Seedling Emergence)

Terrestrial plant toxicity, Tier 1 (vegetative vigor)

Aquatic plant toxicity test using Lemna spp. Tiers I 

and II

N/A - Pyridaben 

Chemical # and Name: 129105

Pyridaben 

17-Nov-2011

GENERIC

ID # GDCI-129105-855

C,H,A

C,H,A

C,H,A

C,H,A

C,H,A

C,H,A

C,H,A

C,H,A

TGAI or PAIRA

TGAI or PAIRA

TGAI or PAIRA

TEP

TEP

TEP

TEP

TEP or TGAI

24

24

24

24

24

12

12

12

Page 1 of 

(5)

(6)

(4)

(17)

(16)

(3)

(2)

(14)

N

N

N

N

N

N

N

N

3
OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

 

Nontarget Plant Protection Data Requirements (Conventional 

Chemical)

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

850.5400

850.1075

850.1350

850.1400

850.1710

850.1735

850.1850

850.3040

Algal toxicity, Tiers 1 and II

Fish acute toxicity test, freshwater and marine

Mysid chronic toxicity test

Fish early-life stage toxicity test

Oyster BCF

Whole sediment: acute freshwater invertebrates

Aquatic food chain transfer

Field testing for pollinators

N/A - Pyridaben 

Chemical # and Name: 129105

Pyridaben 

17-Nov-2011

GENERIC

ID # GDCI-129105-855

C,H,A

C,H,A

C,H,A

C,H,A

C,H,A

C,H,A

C,H,A

C,H,A

TEP or TGAI

TGAI, TEP

TGAI

TGAI

TGAI, PAI, Degr

TGAI

TGAI, PAI, Degr

TEP

12

12

12

12

12

12

12

24

Page 2 of 

(15)

(18)

(11)

(8)

(11, 13)

(10, 12)

N

N

N

N

N

N

N

N

3
Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

 

Toxicology Data Requirements (Conventional Chemical)

870.7800

SS-1066

SS-1069

SS850.1000

Immunotoxicity

Chronic Sediment - Hyalella Azteca

Chronic Sediment - Chironomus dilutus

Chronic Estuarine/Marine Sediment Testing

N/A - Pyridaben 

Chemical # and Name: 129105

Pyridaben 

17-Nov-2011

GENERIC

ID # GDCI-129105-855

C,H,A

C,H,A

C,H,A

C,H,A

TGAI 12

24

24

24

Page 3 of 

(1)

(9)

(7)

(7)

N

N

N

N

3
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

N/A - Pyridaben 

GDCI-129105-855

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

Two immunotoxicity studies are required to address both the rat and mouse.

These studies must be conducted at the highest single application rate for pyridaben (1.0 lbs a.i./A on ornamentals) and with a typical end use product containing pyridaben. Tier II data should 

be submitted for that species. 

These studies must be conducted at the highest single application rate for pyridaben (1.0 lbs a.i./A on ornamentals) and with a typical end use product containing pyridaben. Tier II data should 

be submitted for that species.

The Agency is requiring an anaerobic aquatic metabolism study conducted at a pH that is typical of an aquatic environment where pyridaben is applied. 

The Agency is requiring an aerobic soil metabolism study conducted on three additional relevant soils of different organic carbon content, pH, clay content, and microbial biomass.

The Agency is requiring an aerobic aquatic metabolism study conducted at a pH that is typical of an aquatic environment where pyridaben is applied. 

Testing is required if the soil partition coefficient (Kd) is equal to or greater than 50 and the pesticide is persistent (e.g., half-life in sediment is equal to or less than 10 days) in either the aerobic 

soil or aquatic metabolism studies. Registrants must submit a study protocol for review by Agency prior to initiation of study.

Testing is required if the soil partition coefficient (Kd) is equal to or greater than 50 and the pesticide is persistent (e.g., half-life in sediment is equal to or less than 10 days) in either the aerobic 

soil or aquatic metabolism studies. Registrants must submit a study protocol for review by Agency prior to initiation of study. 

Testing is required if the soil partition coefficient (Kd) is equal to or greater than 50 and the pesticide is persistent (e.g., half-life in sediment is equal to or less than 10 days) in either the aerobic 

soil or aquatic metabolism studies. Registrants must submit a study protocol for review by Agency prior to initiation of study.

Required if any of the following conditions are met: (i) data from other sources (Experimental Use Permit program, university research, registrant submittals, etc.) indicate potential adverse 

effects on colonies, especially effects other than acute mortality (reproductive, behavioral, etc.); (ii) data from residual toxicity studies indicate extended residual toxicity; (iii) data derived from 

studies with arthropods other than bees that indicate potential chronic, reproductive, or behavioral effects.

Required based on the results of fish or aquatic nontarget organisms accumulation studies (guidelines 850.1730 and 850.1950).

Pyridaben registrants must submit a study protocol for review by the Agency prior to initiation of the field testing. 

Pyridaben registrants must submit a study protocol for review by the Agency prior to initiation of the aquatic food chain transfer study.

In order to fulfill the guideline requirement for aquatic vascular plants, additional Tier I data must be submitted for a vascular aquatic plant (i.e. duckweed) exposed to pyridaben at a 

concentration up to the solubility limit of pyridaben (12 ug ai/L0 or test the formulated product to insure it doesn't enhance solubility and/or effects. If the Tier I data result in >50% effects to the 

test species, Tier II data should be submitted for that species. 

In order to fulfill the guideline requirement for algae, additional Tier I data must be submitted for 4 species of algae exposed to pyridaben at a concentration up to the solubility limit of pyridaben 

(12 ug ai/L) or test the formulated product to insure it doesn't enhance solubility and/or effects. If the Tier I data result in >50% effects to any test species, Tier II data should be submitted for 

Case # and Name:

DCI Number:

Page: 1 of

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. 

These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement.

Use Categories Key:

A - Terrestrial food crop

C - Terrestrial nonfood crop

H - Greenhouse food crop

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

N/A - Pyridaben 

GDCI-129105-855

16

17

18

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

that species.

Environmental Chemistry Analytical Method and Independent Laboratory Validation for Residues in Water (see 40 CFR section 158.1300 note 7)

Environmental Chemistry Analytical Method and Independent Laboratory Validation for Residues in Soil (see 40 CFR sectoin 158.1300 note 7)

Data are required on estuarine species if the product is: (i) intended for direct application to the estuarine or marine environment; (ii) expected to enter this environment in significant 

concentrations because of its expected use or mobility patterns, and (iii) if the acute LC50 or EC50 < 1 mg/l; or (iv) if the estimated environmental concentration in water is equal to or greater 

than 0.01 of the acute EC50 or LC50 and any of the following conditions exist: (a) studies of other organisms indicate the reproductive physiology of fish and/or invertebrates may be affected; 

(b) physicochemical properties indicate bioaccumulation of the pesticide; (c) the pesticide is persistent in water (e.g., half-life in water greater than 4 days).

Case # and Name:

DCI Number:

Page: 2 of 2
United States Environmental Protection Agency 

Washington, D.C. 20460

LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE

Case # and Name: N/A - Pyridaben 

Page: 1 of 1

33906 NISSAN CHEMICAL INDUSTRIES LTD

Co. Nr. Company Name Agent For Company

LEWIS & HARRISON, LLC 122 C STREET, N.W., SUITE 505

Address City ZIP

WASHINGTON 20001 

OMB Approval 2070-0174

State

DC

 DCI Number: GDCI-129105-855
LINKS TO FORMS:

The pesticide registration forms that are listed below can be found at:

http://www.epa.gov/opprd001/forms/

Link to Confidential Statement of Formula and Instructions (Form # 8570-4)

http://www.epa.gov/opprd001/forms/8570-4.pdf

Certification of Attempt to Enter Into an Agreement With Registrants for 

Development of Data (Form # 8570-32)

http://www.epa.gov/opprd001/forms/8570-32.pdf

Certification With Respect to Citation of Data (Form # 8570-34)

http://www.epa.gov/opprd001/forms/8570-34.pdf