Initial to indicate certification as to information on this page

(full text of certification is on page one).

Date

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. 

Use additional sheet(s) if necessary.

2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product 

Registration

5. I wish to cancel 

this product 

registration 

voluntarily

6. Generic Data 7. Product Specific Data

6a. I am claiming a Generic Data 

Exemption because I obtain the 

active ingredient from the source 

EPA registration number listed 

below.

6b. I agree to satisfy Generic Data

Requirements as indicated on the 

attached form entitled 

"Requirements Status and 

Registrant's Response."

7a. My product is an MUP and I 

agree to satisfy the MUP 

requirement on the attached form

entitled "Requirements Status and

Registrant's Response."

7b. My product is an EUP and I 

agree to satisfy the EUP 

requirement on the attached form 

entitled "Requirements Status and 

Registrant's Response."

OMB Approval 2070-0174

1. Company Name and Address

 

0032 - Daminozide

Chemical # and Name: 035101

Daminozide

22-Sep-2010

GENERIC

ID # GDCI-035101-915

United States Environmental Protection Agency

Washington, D.C. 20460

DATA CALL-IN RESPONSE

Page of 1 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

Signature and Title of Company's Authorized Representative ______________________________________________________

10. Name of Company

N/A N/A

9. Date

11. Phone Number 
Initial to indicate certification as to information on this page (full text of certification is on page one) 

13. Phone Number

10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any 

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

12. Name of Company

11. Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

 

Environmental Fate Data Requirements (Conventional 

Chemical)

Nontarget Plant Protection Data Requirements (Conventional 

Chemical)

Product Chemistry Data Requirements (Conventional 

Chemical)

835.1410

835.6100

835.6200

835.8100

850.4100

850.4150

830.7050

Laboratory volatilization from soil

Terrestrial field dissipation

Aquatic field dissipation

Field volatility from soil

Terrestrial Plant Toxicity (Seedling Emergence)

Terrestrial plant toxicity, Tier 1 (vegetative vigor)

UV/Visible absorption

0032 - Daminozide

Chemical # and Name: 035101

Daminozide

22-Sep-2010

GENERIC

ID # GDCI-035101-915

I,M

I,M

I,M

I,M

I,M

I,M

I,M

TEP

TEP

TEP

TEP

TEP

TEP

TGAI/PAI

12

24

24

12

12

12

12

Page 1 of 

(2)

(4, 8, 15, 18)

(1, 8, 15, 17)

(5)

(5, 6)

N

N

N

N

N

N

N

2
Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

 

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

Toxicology Data Requirements (Conventional Chemical)

850.2100

850.2300

870.3250

870.3465

870.6200

870.7800

SS-1100

Avian acute oral toxicity test

Avian reproduction test

90-day dermal toxicity

90-day inhalation toxicity

Neurotoxicity screening battery

Immunotoxicity

Formation of Unsymmetrical Dimethylhydrazine

0032 - Daminozide

Chemical # and Name: 035101

Daminozide

22-Sep-2010

GENERIC

ID # GDCI-035101-915

I,M

I,M

I,M

I,M

I,M

I,M

I,M

EP; PAI; TGAI

TGAI

EP; PAI; TGAI

TGAI

TGAI

TGAI

EP; PAI; TGAI

12

24

24

24

24

24

24

Page 2 of 

(7, 11, 13)

(10, 12)

(9, 16)

(3, 19)

(20, 21)

(14)

N

N

N

N

N

N

N

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

0032 - Daminozide

GDCI-035101-915

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

Requirement for terrestrial uses is based on potential for aquatic exposure and if pesticide residues have the potential for persistence, mobility, nontarget aquatic toxicity or bioaccumulation. Not 

required for aquatic residential uses.

Requirement based on use patterns and other pertinent factors including, but not limited to, Henry's Law Constant. In view of methodological difficulties with the study of photodegradation in air, 

prior consultation with the Agency regarding the protocol is recommended before the test is performed.

Required if there is the likelihood of significant repeated inhalation exposure to the pesticide as a gas, vapor, or aerosol.

Required for aquatic food and nonfood crop uses for aquatic sites that are intermittently dry. Such sites include, but are not limited to cranberry bogs and rice paddies.

Required for all outdoor pesticide uses except for known phytotoxicants such as herbicides, desiccants, defoliants, and plant growth regulators.

Generally not required for granular formulations. May be requested on a case-by-case basis.

For greenhouse and indoor end-use products, data using the TGAI are required to support manufacturing use products to be reformulated or to support these same end-use products when 

there is no registered manufacturing use product. For greenhouse and indoor end-use products, data using the TGAI are required to support manufacturing-use products to be reformulated into

these same end-use products or to support end-use products when there is no registered manufacturing-use product. 

Environmental chemistry methods used to generate data associated with this study must include results of a successful confirmatory method trial by an independent laboratory. The 

environmental chemistry methods must include a statement of no data confidentiality claims, i.e., non-CBI. Test standards and procedures for independent laboratory validation are available as 

addenda to the guideline for this test requirement.

EP testing is required if the product, or any component of it, may increase dermal absorption of the active ingredient(s) as determined by testing using the TGAI, or increase toxic or 

pharmacologic effects.

Data using the TGAI are required to support all outdoor end-use product uses including turf. Data are generally not required to support end use products in the form of a gas, a highly volatile 

liquid, a highly reactive solid, or a highly corrosive material. 

Data using the TGAI are required to support all outdoor end-use product uses including turf. Data are generally not required to support end use products in the form of a gas, a highly volatile 

liquid, a highly reactive solid, or a highly corrosive material. 

Data required on both mallard and bobwhite quail.

Data are required on a passerine species.

Daminozide's metabolite/degradate, unsmmetrical dimethylhydrazine (UDMH), is classified as a probable human carcinogen and small amounts present in the spray solution could result in risks to

handlers. The concentration of UDMH can increase when spray solutions sit in a tank for up to 24 hours. Please submit study protocol to the Agency for review.

Conduct with TGAI & Degr

Conduct with TGAI

Case # and Name:

DCI Number:

Page: 1 of

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. 

These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement.

Use Categories Key:

I - Greenhouse nonfood crop

M - Indoor nonfood use

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

0032 - Daminozide

GDCI-035101-915

17

18

19

20

21

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

Both daminozide and unsymmetrical dimethlyhydrazine (UDMH) must be used as test substances.

Both daminoxide and unsymmetrical dimethylhydrazine (UDMH) must be used as test substances.

Based on estimates of the magnitude and duration of human exposure, studies of shorter duration, e.g., 21 or 28-days, may be sufficient to satisfy this requirement. Registrants should consult 

with the Agency to determine whether studies of shorter duration would meet this requirement.

All 90-day subchronic studies in rats can be designed to simultaneously fulfill the requirements of the 90-day neurotoxicity study using separate groups of animals for testing. Although the 

subchronic guidelines include the measurement of neurological endpoints, they do not meet the requirement of the 90-day neurotoxicity study (guideline 870.6200).

Additional measurements such as cholinesterase activity for certain pesticides, e.g., organophosphates and some carbamates, will also be required. The route of exposure must correspond 

with the primary route of exposure.

Case # and Name:

DCI Number:

Page: 2 of 2
United States Environmental Protection Agency 

Washington, D.C. 20460

LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE

Case # and Name: 0032 - Daminozide

Page: 1 of 1

400

62097

CHEMTURA CORPORATION

FINE AGROCHEMICALS, LTD

Co. Nr. Company Name Agent For Company

SCIREG, INC.

199 BENSON ROAD 

12733 DIRECTOR'S LOOP

Address City ZIP

MIDDLEBURY

WOODBRIDGE

06749 

22192 

OMB Approval 2070-0174

State

CT

VA

 DCI Number: GDCI-035101-915
LINKS TO FORMS:

The pesticide registration forms that are listed below can be found at:

http://www.epa.gov/opprd001/forms/

Link to Confidential Statement of Formula and Instructions (Form # 8570-4)

http://www.epa.gov/opprd001/forms/8570-4.pdf

Certification of Attempt to Enter Into an Agreement With Registrants for 

Development of Data (Form # 8570-32)

http://www.epa.gov/opprd001/forms/8570-32.pdf

Certification With Respect to Citation of Data (Form # 8570-34)

http://www.epa.gov/opprd001/forms/8570-34.pdf