Initial to indicate certification as to information on this page (full text of certification is on page one). Date INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary. 2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product Registration 5. I wish to cancel this product registration voluntarily 6. Generic Data 7. Product Specific Data 6a. I am claiming a Generic Data Exemption because I obtain the active ingredient from the source EPA registration number listed below. 6b. I agree to satisfy Generic Data Requirements as indicated on the attached form entitled "Requirements Status and Registrant's Response." 7a. My product is an MUP and I agree to satisfy the MUP requirement on the attached form entitled "Requirements Status and Registrant's Response." 7b. My product is an EUP and I agree to satisfy the EUP requirement on the attached form entitled "Requirements Status and Registrant's Response." OMB Approval 2070-0174

1. Company Name and Address 0032 - Daminozide Chemical # and Name: 035101 Daminozide 22-Sep-2010 GENERIC ID # GDCI-035101-915 

### United States Environmental Protection Agency

Washington, D.C. 20460 DATA CALL-IN RESPONSE 1 Page of 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law. Signature and Title of Company's Authorized Representative ______________________________________________________ 10. Name of Company N/A N/A

9. Date

11. Phone NumberInitial to indicate certification as to information on this page (full text of certification is on page one) 13. Phone Number 10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.
12. Name of Company 11. Date OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

Environmental Fate Data Requirements (Conventional Chemical)

Nontarget Plant Protection Data Requirements (Conventional Chemical)

Product Chemistry Data Requirements (Conventional Chemical) 835.1410 835.6100 835.6200 835.8100

850.4100 850.4150

830.7050 Laboratory volatilization from soil

Terrestrial field dissipation Aquatic field dissipation Field volatility from soil

Terrestrial Plant Toxicity (Seedling Emergence) Terrestrial plant toxicity, Tier 1 (vegetative vigor)

UV/Visible absorption 0032 - Daminozide Chemical # and Name: 035101 Daminozide 22-Sep-2010 GENERIC ID # GDCI-035101-915

I,M I,M I,M I,M

I,M I,M

I,M TEP TEP TEP TEP

TEP TEP

TGAI/PAI 12 24 24 12

12 12

12 1 of Page

(2) (4, 8, 15, 18) (1, 8, 15, 17)

(5) (5, 6) N

N N N

N N

N 2Date OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Terrestrial and Aquatic Nontarget Organisms Data Requirements (Conventional Chemical)

Toxicology Data Requirements (Conventional Chemical) 850.2100 850.2300

870.3250 870.3465 870.6200 870.7800

SS-1100 Avian acute oral toxicity test

Avian reproduction test
90-day dermal toxicity 90-day inhalation toxicity Neurotoxicity screening battery Immunotoxicity
Formation of Unsymmetrical Dimethylhydrazine 0032 - Daminozide Chemical # and Name: 035101 Daminozide 22-Sep-2010 GENERIC ID # GDCI-035101-915

I,M I,M

I,M I,M I,M I,M

I,M EP; PAI; TGAI TGAI

EP; PAI; TGAI TGAI TGAI TGAI

EP; PAI; TGAI 12 24

24 24 24 24

24 2 of Page

(7, 11, 13) (10, 12)
(9, 16) (3, 19) (20, 21)

(14) N N

N N N N

N 2

### United States Environmental Protection Agency Washington, D.C. 20460 FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS 0032 - Daminozide GDCI-035101-915

1 2 3 4 5 6 7
8
9 10 11 12 13 14 15 16 Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

Requirement for terrestrial uses is based on potential for aquatic exposure and if pesticide residues have the potential for persistence, mobility, nontarget aquatic toxicity or bioaccumulation. Not required for aquatic residential uses. Requirement based on use patterns and other pertinent factors including, but not limited to, Henry's Law Constant. In view of methodological difficulties with the study of photodegradation in air, prior consultation with the Agency regarding the protocol is recommended before the test is performed. Required if there is the likelihood of significant repeated inhalation exposure to the pesticide as a gas, vapor, or aerosol. Required for aquatic food and nonfood crop uses for aquatic sites that are intermittently dry. Such sites include, but are not limited to cranberry bogs and rice paddies. Required for all outdoor pesticide uses except for known phytotoxicants such as herbicides, desiccants, defoliants, and plant growth regulators. Generally not required for granular formulations. May be requested on a case-by-case basis. For greenhouse and indoor end-use products, data using the TGAI are required to support manufacturing use products to be reformulated or to support these same end-use products when there is no registered manufacturing use product. For greenhouse and indoor end-use products, data using the TGAI are required to support manufacturing-use products to be reformulated into these same end-use products or to support end-use products when there is no registered manufacturing-use product. Environmental chemistry methods used to generate data associated with this study must include results of a successful confirmatory method trial by an independent laboratory. The environmental chemistry methods must include a statement of no data confidentiality claims, i.e., non-CBI. Test standards and procedures for independent laboratory validation are available as addenda to the guideline for this test requirement. EP testing is required if the product, or any component of it, may increase dermal absorption of the active ingredient(s) as determined by testing using the TGAI, or increase toxic or pharmacologic effects. Data using the TGAI are required to support all outdoor end-use product uses including turf. Data are generally not required to support end use products in the form of a gas, a highly volatile liquid, a highly reactive solid, or a highly corrosive material. Data using the TGAI are required to support all outdoor end-use product uses including turf. Data are generally not required to support end use products in the form of a gas, a highly volatile liquid, a highly reactive solid, or a highly corrosive material. Data required on both mallard and bobwhite quail. Data are required on a passerine species. Daminozide's metabolite/degradate, unsmmetrical dimethylhydrazine (UDMH), is classified as a probable human carcinogen and small amounts present in the spray solution could result in risks to handlers. The concentration of UDMH can increase when spray solutions sit in a tank for up to 24 hours. Please submit study protocol to the Agency for review. Conduct with TGAI & Degr Conduct with TGAI Case # and Name: DCI Number: 1 Page: of

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement. Use Categories Key: I - Greenhouse nonfood crop M - Indoor nonfood use 2

### United States Environmental Protection Agency Washington, D.C. 20460 FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS 0032 - Daminozide GDCI-035101-915

17 18 19 20 21 Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

Both daminozide and unsymmetrical dimethlyhydrazine (UDMH) must be used as test substances. Both daminoxide and unsymmetrical dimethylhydrazine (UDMH) must be used as test substances. Based on estimates of the magnitude and duration of human exposure, studies of shorter duration, e.g., 21 or 28-days, may be sufficient to satisfy this requirement. Registrants should consult with the Agency to determine whether studies of shorter duration would meet this requirement. All 90-day subchronic studies in rats can be designed to simultaneously fulfill the requirements of the 90-day neurotoxicity study using separate groups of animals for testing. Although the subchronic guidelines include the measurement of neurological endpoints, they do not meet the requirement of the 90-day neurotoxicity study (guideline 870.6200). Additional measurements such as cholinesterase activity for certain pesticides, e.g., organophosphates and some carbamates, will also be required. The route of exposure must correspond with the primary route of exposure. Case # and Name: DCI Number: 2 Page: of 2

### United States Environmental Protection Agency Washington, D.C. 20460 LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE 0032 - Daminozide Case # and Name: 1 Page: of 1

400 62097 CHEMTURA CORPORATION

FINE AGROCHEMICALS, LTD Co. Nr. Company Name Agent For Company

SCIREG, INC. 199 BENSON ROAD 12733 DIRECTOR'S LOOP Address City ZIP MIDDLEBURY WOODBRIDGE 06749 22192 OMB Approval 2070-0174

State CT VA DCI Number: GDCI-035101-915

# LINKS TO FORMS: The pesticide registration forms that are listed below can be found at: http://www.epa.gov/opprd001/forms/ Link to C onfidential Statement of Formula and Instructions (Form # 8570 -4 

# ) http://www.epa.gov/opprd001/forms/8570 - 4.pdf C ertification of Attempt to Enter Into an Agreement With Registrants for Development of Data (Form # 8570 - 32 

# ) http://www.epa.gov/opprd001/forms/8570 - 32.pdf C ertification With Respect to Citation of Data (Form # 8570 - 34 

# ) http://www.epa.gov/opprd001/forms/8570 - 34.pdf