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                                                                    EXHIBIT 10.8

                                 ENDOCARE, INC.

                               FULL-RECOURSE NOTE

$1,028,125                                                      November 2, 1999
                                                              Irvine, California

        FOR VALUE RECEIVED, Jerry W. Anderson ("Maker") promises to pay to the
order of Endo care, Inc., a Delaware corporation (the "Corporation"), at its
corporate offices at 7 Studebaker, Irvine, California 92618, the principal sum
of One Million Twenty Eight Thousand and One Hundred Twenty Five Dollars
($1,028,125), together with all accrued interest thereon, upon the terms and
conditions specified below.

        1. PURCHASE MONEY INDEBTEDNESS. The proceeds of this Note shall be
applied solely and exclusively to the payment of the purchase price of 175,000
shares of the Corporation's common stock acquired this day by Maker.

        2. INTEREST. Interest shall accrue on the unpaid balance outstanding
from time to time under this Note at the rate of 5.99% per annum, compounded
semi-annually. Accrued and unpaid interest shall become due and payable annually
on the last day of September each year during the term of this Note.

        3. DUE DATE FOR PRINCIPAL BALANCE. The outstanding principal balance of
this Note shall become due and payable in one lump sum on September 30, 2003.

        4. PAYMENT. Payment shall be made in lawful tender of the United States
and shall be applied first to the payment of all accrued and unpaid interest and
then to the payment of principal. Prepayment of the principal balance of this
Note, together with all accrued and unpaid interest on the portion of principal
so prepaid, may be made in whole or in part at any time without penalty.

        5. EVENTS OF ACCELERATION. The entire unpaid principal balance of this
Note, together with all accrued and unpaid interest, shall become immediately
due and payable prior to the specified due date of this Note upon the occurrence
of one or more of the following events:

                A. the failure of the Maker to pay any installment of accrued
        interest under this Note when due and the continuation of such default
        for more than thirty (30) days; or

                B. the failure of the Maker to pay when due any portion of the
        principal balance of this Note, together with the accrued interest
        thereon, which becomes due and payable under Paragraph 6 of this Note
        and the continuation of such default for more than thirty (30) days; or

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                C. the expiration of the thirty (30)-day period following the
        date the Maker ceases for any reason to remain in the employ or service
        of the Corporation; or

                the insolvency of the Maker, the commission of any act of
        bankruptcy by the Maker, the execution by the Maker of a general
        assignment for the benefit of creditors, the filing by or against the
        Maker of any petition in bankruptcy or any petition for relief under the
        provisions of the Federal bankruptcy act or any other state or Federal
        law for the relief of debtors and the continuation of such petition
        without dismissal for a period of thirty (30) days or more, the
        appointment of a receiver or trustee to take possession of any property
        or assets of the Maker or the attachment of or execution against any
        property or assets of the Maker.

        6. SPECIAL ACCELERATION EVENT. In the event the Maker sells or otherwise
transfers for value one or more shares of the Corporation's common stock
purchased with the proceeds of this Note, then a portion of the unpaid principal
balance of this Note equal to the aggregate purchase price of those shares shall
become immediately due and payable, together with all accrued and unpaid
interest on that principal portion.

        7. EMPLOYMENT/SERVICE. The Maker shall be deemed to continue in
employment or service with the Corporation for so long as he renders services in
an employee or consultant status to the Corporation or one or more of the
Corporation's fifty percent (50%) or more owned (directly or indirectly)
subsidiaries.

        8. FULL-RECOURSE OBLIGATION. The Maker shall remain personally liable
for payment of the entire outstanding balance of this Note, and any and all
assets of the Maker may be applied to the satisfaction of the Maker's
obligations hereunder.

        9. COLLECTION. If action is instituted to collect this Note, the Maker
promises to pay all costs and expenses (including reasonable attorney fees)
incurred in connection with such action.

        10. WAIVER. A waiver of any term of this Note must be made in writing
and signed by a duly-authorized officer of the Corporation and any such waiver
shall be limited to its express terms.

        No delay by the Corporation in acting with respect to the terms of this
Note shall constitute a waiver of any breach, default, or failure of a condition
under this Note.

        The Maker waives presentment, demand, notice of dishonor, notice of
default or delinquency, notice of acceleration, notice of protest and
nonpayment, notice of costs, expenses or losses and interest thereon, notice of
interest on interest and diligence in taking any action to collect any sums
owing under this Note.

        11. CONFLICTING AGREEMENTS. In the event of any inconsistencies between
the terms of this Note and the terms of any other document related to the loan
evidenced by the Note, the terms of this Note shall prevail.



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        12. GOVERNING LAW. This Note shall be construed in accordance with the
laws of the State of California without resort to that State's conflict-of-laws
rules.


                                        /s/ Jerry W. Anderson
                                       -----------------------------------------
                                       JERRY W. ANDERSON
                                       MAKER








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