UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, DC 20460 

OFFICE OF CHEMICAL SAFETY 

AND POLLUTION PREVENTION 

MEMORANDUM 

DATE: 12/4/2014 

SUBJECT: Deltamethrin. Petition for the Proposed Use of the Insecticide as a Mosquito 

Adulticide: Summary of Analytical Chemistry and Residue Data 

PC Code: 097805 

Decision Number: 484277 

Petition Number: 3F821 0 

Risk Assessment Type: NA 

TXR Number: NA 

MRID Number: 49114112 

DP Barcode: D423045 

Registration Number: 432-RLGU 

Regulatory Action: Section 3 Registration 

Case Number: 7414 

CAS Number: 52918-63-5 

40 CFR: §180.435 

FROM: Douglas Dotson, Ph.D, Chemist J. /)~ Risk Assessment Branch II (RAB2) 

THRU: 

TO: 

Health Effects Division (HED), 7509P 

William Drew, Chemist ~~O _ jl c;:;:::::./--

Michael Doherty, Ph.D., Senior Chemist ~ /( ~ RAB2/HED, 7509P 

Olga Odiott!Richard Gebken, PM Team 10 

InvertebrateN ertebrate Branch II (IVB2) 

Registration Division (RD), 7505P 
Oeltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode 0423045 

Table of Contents 

1.0 Executive Summary ............................................................. ................................................. 4 

2.0 Regulatory Recommendations ....... .................................. ..................................................... 4 

2.1 Data Deficiencies/Data Needs .................................................................................. ........ 4 

2.2 Tolerance Considerations ............................................ ...................................................... 4 

2.2.1 Enforcement Analytical Method/Multi residue Methods .......................................... 4 

2.2.2 Recommended Tolerances ...................................................................... ..... ............. 5 

2.2.3 Revisions to Petitioned-For Tolerances .................................................................... 5 

2.2.4 International Harmonization ..................................................................................... 5 

2.3 Label Recommendations .................................................................................................. 5 

2.4 Submittal of Analytical Reference Standards (860.1650) ............................................... 6 

3.0 Chemical Identity ................................................................. ........................ .... .......... .... ...... 6 

3.1 Nomenclature .............. ... ........ ...................................... ........ ............................................ 7 

3.2 Physicochemical Characteristics ...................................................................................... 8 

3.3 Pesticide Use Pattern/Directions for Use (860.1200) .......................................... ............ 8 

4.0 Metabolite/Degradate Residue Profile ................................................................................. 9 

4.1 Nature of the Residue and Summary of Environmental Degradation ............................. 9 

5.0 Residue Profile ................................................................................................................... 10 

5.1 Residue Analytical Methods (860.1340) ...................................................................... 10 

5 .1.1 Data Collection Methods ........................................................................................ 10 

5.1.2 Multi-Residue Methods (860.1360) ........................................................................ 11 

5.1.3 Tolerance Enforcement Methods ............................................................................ 11 

5.2 Storage Stability (860.1380) .......................................................................................... 11 

5.3 Residue Data .................................................................................................................. 12 

5.3.1 Crop Field Trials (860.1 500) .................................................................................. 12 

5.3.2 Field Rotational Crops (860.1900) ............................. : ........................................... 18 

5.3.3 Processed Food and Feed (860.1520) ..................................................................... 18 

5.3.4 Meat, Milk, Poultry and Eggs (860.1480) .............................................................. 18 

5.3.5. Food Handling (860.1460) ........................ .... .......................................................... 20 

5.3.6 Water, Fish and Irrigated Crops (860.1400) ............................................. ......... ..... 20 

5.4 Food Residue Profile ...................................................................................................... 20 

6.0 Tolerance Derivation ................ .............................. ........................................ ................... 20 

References ..................................................................................................................................... 21 

Attachment 1: International Residue Limit Status ....................................................................... 22 

Page 2 of25 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 3 of 25

1.0 Executive Summary

Deltamethrin (with CAS registry number 52918-63-5, and CAS name (1R,3R)-R-cyano(3-

phenoxyphenyl)methyl 3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylate) is a 

broad-spectrum pyrethroid insecticide that is registered in the US for direct application to a wide 

variety of food/feed crops and for use on stored grains. In addition, deltamethrin is registered for 

use in food/feed handling establishments (FHEs), and a tolerance of 0.05 ppm is established for 

this use. The registrant, Bayer Environmental Science, petitioned the Agency to amend 40CFR 

§180.435(a)(2) to include the use of deltamethrin as a wide-area mosquito adulticide in the 

airspace over agricultural crops and proposed that the 0.05 ppm tolerance apply to the adulticide 

use as well. 

Tolerances are established for the combined residues of deltamethrin and its major metabolites,

trans-deltamethrin and alpha-R-deltamethrin, in/on plant commodities at levels ranging from 

0.03 ppm in sweet corn ears (K+CWHR) to 65 ppm in aspirated grain fractions (40 CFR 

§180.435[a][1]). Tolerances have also been established for residues in livestock commodities. 

Deltamethrin residues of concern (ROCs) are comprised of the active ingredient (ai), cisdeltamethrin, along with its isomeric metabolites, trans-deltamethrin and alpha-R-deltamethrin. 

The nature of deltamethrin residues in plants and animals is adequately understood, based on 

tomato, cotton, apple, goat, and poultry metabolism studies. The three deltamethrin isomers (cis,

trans-, and alpha-R-) are the major [14C]-residues in plant commodities, and in milk, eggs, meat,

and fat. For purposes of both tolerance enforcement and risk assessment, HED has concluded 

that the ROCs for both plant and livestock commodities include the cis-, trans- and alpha-Risomers. 

Bayer performed mosquito adulticide residue trials in accordance with a protocol that was 

previously approved by HED’s Chemistry Science Advisory Council (ChemSAC) and submitted 

a report of the results (MRID 49114112). Residue results are supported by adequate storage 

stability and analytical method data. Residues were below 0.05 ppm in all samples of leaf lettuce 

treated at both the 1x and 1⁄2x rate. In grass forage, residues ranged up to 0.087 ppm in samples 

treated at a 1x rate. In alfalfa forage, residues ranged up to 0.070 ppm in samples treated at a 1x 

rate. Residues in alfalfa hay and grass hay are not being considered for tolerance-setting 

purposes for crops because hay is a dried commodity. In all trials, residues increased with an 

increase in number of treatments. 

Adequate methods, utilizing gas chromatography with electron capture detection (GC/ECD), are 

available for enforcing tolerances for residues of deltamethrin in plant commodities, as described 

in Pesticide Analytical Manual (PAM) Volume II, Section 180.422. Another GC/ECD method 

(Method HRAV-22) is available for enforcing tolerances in livestock commodities. Adequate 

confirmatory method validation data have been submitted for these methods, along with 

adequate independent laboratory validation (ILV) trials. 

Codex and Canada have established MRLs for residues of deltamethrin in/on numerous

commodities. An International Residue Limit Status sheet is appended as Attachment 1. 

Harmonization of MRLs is not an issue for this risk assessment.
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 4 of 25

2.0 Regulatory Recommendations

HED has examined the residue chemistry database for deltamethrin. There are no residue 

chemistry issues that would preclude establishing a tolerance for all crops as a result of the use of 

deltamethrin as a mosquito adulticide. HED does not object to the amending of 40CFR 

§180.435(a)(2) to include the use of deltamethrin as a wide-area mosquito adulticide. 

HED recommends that the tolerance expression for deltamethrin, cited under 40CFR 

§180.435[a][2], be amended to read as follows: 

A tolerance of 0.05 ppm is established for residues of the insecticide deltamethrin, 

including its metabolites and degradates, in or on all raw agricultural commodities 

and processed food or feed from use of deltamethrin in food or feed handling 

establishments where food/feed and food/feed products are held, processed, 

prepared and/or served, or as a wide-area mosquito adulticide. Compliance with 

the tolerance level specified is to be determined by measuring only deltamethrin 

[(1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylic acid (S)-

alpha-cyano-3-phenoxybenzyl ester], and its major metabolites, trans

deltamethrin [(S)-alpha-cyano-m-phenoxybenzyl(1R,3S)-3-(2,2-dibromovinyl)-

2,2-dimethylcyclopropanecarboxylate] and alpha-R-deltamethrin [(R)-alphacyano-m-phenoxybenzyl-(1R,3R)-3-(2,2-dibromovinyl)-2,2-

dimethylcyclopropanecarboxylate] in or on the commodity. 

 

The use directions in 40CFR §180.435[a][2](i and ii) should be deleted because use directions 

are not necessary or needed in the 40CFR listing for deltamethrin. 

2.1 Data Deficiencies/Data Needs

None.

2.2 Tolerance Considerations

2.2.1 Enforcement Analytical Method/Multiresidue Methods

Adequate GC/ECD methods are available for enforcing tolerances for residues of deltamethrin in 

both plant and animal commodities. A GC/ECD method is available in PAM Volume II (Section 

180.422) for enforcing tolerances for residues of deltamethrin, along with a modified version of 

this method (Method ENC 8/92) for analysis of deltamethrin in plant commodities. 

Two other GC/ECD methods are also available for enforcing deltamethrin tolerances in plant 

commodities. Method ENC-6/92 is for determining residues in grain crops and processed 

fractions, while Method HRAV-20 is for determining residues in other food/feed crops. 

Adequate confirmatory method validation, radiovalidation, and ILV data have been submitted 

for these GC/ECD methods, and HED has concluded that an Agency validation was not required 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 5 of 25

for these methods. The reported LOQs for each deltamethrin isomer range from 0.005 to 0.050 

ppm, depending on the plant commodity. 

Another GC/ECD method (Method HRAV-22) is available for enforcing tolerances in livestock 

commodities. Adequate confirmatory method validation data have been submitted for this 

method, along with an adequate ILV trial. The reported LOQ for each deltamethrin isomer is 

0.005 ppm in all livestock matrices, except fat, which has an LOQ of 0.015 ppm. 

Multiresidue methods data for cis-deltamethrin and trans-deltamethrin were previously sent to 

the Food and Drug Administration (FDA). Cis-deltamethrin is completely recovered through 

Methods 302 and 303, and partially recovered through Method 304. Trans-Deltamethrin is 

partially recovered through Method 303, but not recovered through Method 304. 

2.2.2 Recommended Tolerances

As stated above, HED recommends that the tolerance expression and use directions for 

deltamethrin, cited under 40CFR §180.435[a][2], be amended to read as follows: 

A tolerance of 0.05 ppm is established for residues of the insecticide deltamethrin, 

including its metabolites and degradates, in or on all raw agricultural commodities and 

processed food or feed from use of deltamethrin in food or feed handling establishments 

where food/feed and food/feed products are held, processed, prepared and/or served, or as 

a wide-area mosquito adulticide. Compliance with the tolerance level specified is to be 

determined by measuring only deltamethrin [(1R,3R)-3-(2,2-dibromovinyl)-2,2-

dimethylcyclopropanecarboxylic acid (S)-alpha-cyano-3-phenoxybenzyl ester], and its 

major metabolites, trans deltamethrin [(S)-alpha-cyano-m-phenoxybenzyl(1R,3S)-3-(2,2-

dibromovinyl)-2,2-dimethylcyclopropanecarboxylate] and alpha-R-deltamethrin [(R)-

alpha-cyano-m-phenoxybenzyl-(1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate] in or on the commodity. 

2.2.3 Revisions to Petitioned-For Tolerances

None

2.2.4 International Harmonization

Codex and Canada have established MRLs for residues of deltamethrin in/on numerous

commodities. An International Residue Limit Status sheet is appended as Attachment 1. 

Harmonization of MRLs is not an issue for this risk assessment.

2.3 Label Recommendations

The label contains the following statement: “Apply at a rate not to exceed 0.0014 pounds of 

deltamethrin per acre in any given 24-hour period.” The adulticide residue trials were performed 

at a 3-day retreatment interval, however. As a result, the registrant should revise the label to 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 6 of 25

state that the maximum single application rate is 0.00134 lb ai/A and the minimum re-treatment 

interval is 3 days.

The label also states: “Do not make more than 25 applications per site per year.” In the residue 

trials that were performed, the registrant only made 10 applications. As a result, the registrant 

should revise the label to state that no more than 10 applications per year may be made at the 

maximum application rate of 0.00134 lb ai/A.

The label also states: “Do not exceed 0.036 pounds of AI per acre per year to any site.” This 

maximum value of 0.036 lb ai/A is based on 25 applications per year, rather than 10. As a result, 

the registrant should revise the label to state that 0.0134 lb ai/A is the maximum seasonal 

application rate.

2.4 Submittal of Analytical Reference Standards (860.1650)

The analytical standard for deltamethrin, with an expiration date of 11/18/2015, is currently 

available in the EPA’s National Pesticide Standards Repository (NPSR, electronic 

communication from Theresa Cole of the Biological and Economic Analysis Division’s 

(BEAD’s) Analytical Chemistry Branch (ACB) to William Drew (4/24/2014)). Cis-deltamethrin 

is also currently available (expiration date of 12/7/2015), along with alpha-R-deltamethrin 

(3/1/2018) and trans-deltamethrin (2/19/2015). The registrant is required to maintain reasonable 

amounts of the analytical reference standards for deltamethrin and its individual isomers in the 

NPSR. When necessary, a new reference standard or updated certificate of analysis (COA) 

should be sent to the ACB, which is located at Fort Meade, MD. It should be sent to the 

attention of either Theresa Cole or Thuy Nguyen at the address listed below, along with a letter 

of transmittal. Please note that the full 9-digit ZIP Code is required, or the mail will be 

returned to the registrant. 

USEPA

National Pesticide Standards Repository

Analytical Chemistry Branch/BEAD/OPP

701 Mapes Road

Fort George G. Meade, MD 20755-5350

The letter of transmittal should include the assay of the standard, name of the analytical method 

used, a statement of principal impurities, purification procedures employed, storage 

requirements, and special precautions for safe handling. Replacement of standards may be 

required periodically if supplies are exhausted, if the standards expire, or if decomposition 

occurs during storage. Safety Data Sheets (SDSs) must accompany all analytical standards as 

specified in 29CFR§1910.1200 by the Occupational Safety and Health Administration (OSHA). 

3.0 Chemical Identity

Deltamethrin is a pyrethroid insecticide that kills insects on contact and through ingestion. It is 

used to control apple and pear suckers, plum fruit moths, caterpillars, pea moths, aphids (on 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 7 of 25

apples, plums, and hops), winter moths (on apples and plums), and codling and tortrix moths (on 

apples). It controls aphids, mealy bugs, scale insects and whitefly on glasshouse cucumbers, 

tomatoes, peppers, ornamentals, and potted plants. Formulations include micro-emulsions 

(MEs), emulsifiable concentrates (ECs), wettable powders (WPs), flowable formulations, and 

granules. There are no known incompatibilities with other common insecticides and fungicides. 

Deltamethrin is a synthetic insecticide (based structurally on natural pyrethrins) that rapidly 

paralyzes the insect nervous system, giving a quick knockdown effect. Deltamethrin has a rapid 

disabling effect on feeding insects and it is useful for controlling the vectors of “non-persistent” 

viruses, which can be passed on by the vector within a few minutes of starting to feed on the 

plant. Death of insects seems to be due to irreversible damage to the nervous system that occurs 

when exposure lasts more than a few hours. Deltamethrin poisoning occurs through cuticular 

penetration, or oral uptake. The susceptibility of insects is dependent on a variety of factors, and 

can vary (as with many insecticides) according to the environmental conditions. 

The chemical structure and nomenclature of deltamethrin are presented in Table 3.1. The 

physicochemical properties of the technical grade of deltamethrin are presented in Table 3.2, 

below. 

3.1 Nomenclature

Table 3.1. Test Compound Nomenclature

Compound Chemical Structure

 

Common Name Cis-deltamethrin

Molecular Formula C22H19Br2NO3

Molecular Weight 505.24

Company Experimental Name AEF108569

IUPAC Name (S)-α-cyano-3-phenoxybenzyl (1R,3R)-3-(2,2-dibromovinyl)-2,2-

dimethylcyclopropanecarboxylate

CAS Name (1R,3R)-R-cyano(3-phenoxyphenyl)methyl 3-(2,2-dibromoethenyl)-2,2-

dimethylcyclopropanecarboxylate

CAS Number 52918-63-5

End-use Products (EPs) AlphaMax (No current EPA registration); AMX (No current EPA registration). 

O

O

H

O

Br

Br NC
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 8 of 25

3.2 Physicochemical Characteristics

Table 3.2. Physicochemical Properties of Technical Grade Deltamethrin.*

Parameter Value

Melting Point/Range (°C) 100-102

pH Not available

Density (g/cm3at 25°C) 0.550

Water Solubility (ug/L at 25°C) <0.2

Solvent Solubility (% by weight at 20oC) Acetone 33

Alcohol 0.6

Isopropanol 0.2

Ethyl acetate 25

n-Hexane 0.2

Toluene 23

DMF 38

Dioxane 39

Vapor Pressure (mm Hg at 25oC) [mPa at 25°C] 1.5 x 10-8[1.24 x 10-5]

Dissociation Constant, pKa Does not dissociate.

Octanol/Water Partition Coefficient, KOW (at 25oC) 2.7 x 105

UV/Visible Absorption Spectrum Not available.

* Reference: MARC Briefing Memorandum; D284320; D. Dotson; 5 November 2002. 

Deltamethrin is a solid under ambient conditions, and it has low volatility. The compound has a 

very low solubility in water, and low to high solubility in organic solvents. Its octanol/water 

partition coefficient suggests that accumulation in fatty tissues is possible. 

3.3 Pesticide Use Pattern/Directions for Use (860.1200)

Bayer Environmental Science submitted a proposed label for the mosquito adulticide 

formulation, BES0668 Insecticide. BES0668 is formulated as a liquid and contains 2.0% of the 

active ingredient. It may be applied by ULV truck mounted fogger and portable backpack or 

hand-carried equipment at a single maximum application rate of 0.00134 lb ai/acre in residential, 

industrial, urban, recreational, municipal, agricultural and other areas where adult mosquitoes 

and flies are found. BES0668 is also to be applied in indoor/outdoor livestock and poultry 

facilities. This product is to be applied by Federal, State, Tribal, or local government officials 

responsible for public health or vector control, or by persons certified in the appropriate 

category, authorized by the state or tribal lead pesticide regulatory agency to perform adult 

mosquito control applications, or by persons under their direct supervision, or as allowed by state 

regulations for persons treating private property. A summary of the proposed use pattern is 

presented in Table 3.3, below.
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 9 of 25

The label contains the following statement: “Apply at a rate not to exceed 0.0014 pounds of 

deltamethrin per acre in any given 24-hour period.” The adulticide residue trials were performed 

at a 3-day retreatment interval, however. As a result, the registrant should revise the label to 

state that the maximum single application rate is 0.00134 lb ai/A and the minimum re-treatment 

interval is 3 days.

The label also states: “Do not make more than 25 applications per site per year.” In the residue 

trials that were performed, the registrant only made 10 applications. As a result, the registrant 

should revise the label to state that no more than 10 applications per year may be made at the 

maximum application rate of 0.00134 lb ai/A.

The label also states: “Do not exceed 0.036 pounds of AI per acre per year to any site.” This 

maximum value of 0.036 lb ai/A is based on 25 applications per year, rather than 10. As a result, 

the registrant should revise the label to state that 0.0134 lb ai/A is the maximum seasonal 

application rate.

Conclusions: The directions for use on the proposed label should be revised as discussed above.

4.0 Metabolite/Degradate Residue Profile

4.1 Nature of the Residue and Summary of Environmental Degradation

The nature of the residue in plants, livestock, rats, and rotational crops is adequately understood 

based on acceptable plant and animal metabolism studies. In addition, the environmental 

degradation is understood based on acceptable environmental fate studies. Details of the various 

submitted in support of the metabolism and environmental degradation of deltamethrin as well as 

HED’s conclusions concerning these studies can be found in the Metabolism Assessment Review 

Committee Decision Memo (D286801, D. Dotson and N. McCarroll, 1/14/2003) as well as in the 

Table 3.3. Summary of Directions for Proposed Mosquito Vector Control Use of Deltamethrin

Method of 

Application

Product and 

Formulation

(Reg. No.)

Application 

Rate

(lb ai/A)

Maximum 

No. 

Applications 

per Season

Maximum 

Seasonal 

Application 

Rate

(lb ai/A)

RTI

(days)

Use Directions, 

Application Timing, 

Type and Limitations

Truck mounted 

ULV fogger, 

Ground and 

Hand Held 

Equipment

BES0668 

Insecticide

Reg. No. 432-

RLGU

(0.17 lb ai/gal)

0.00134

lb ai/A

over crops

25

0.036

lb ai/A in 

one year over 

crops

3

More frequent 

applications may be 

made to prevent or 

control a threat to 

public/animal health 

determined by a state, 

tribal or local health or 

vector control agency.
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 10 of 25

previous residue chemistry summary document and risk assessment prepared for deltamethrin 

(D413135, D. Dotson, 6/17/2014 and D413048, D. Dotson, et al., 10/10/2014, respectively). 

HED has determined the plant and livestock ROCs for purposes of tolerance enforcement and 

risk assessment (see Table 4.1.1, below). 

Table 4.1.1. Summary of Deltamethrin Metabolites and Degradates to be Included in Risk 

Assessment and the Tolerance Expression

Matrix Residues in Risk Assessment Residues in the Tolerance Expression

Plants Primary crops Cis-, trans- and alpha-R-deltamethrin Cis-, trans- and alpha-R-deltamethrin

Rotational crops Not Applicable Not applicable

Livestock Ruminants Cis-, trans- and alpha-R-deltamethrin Cis-, trans- and alpha-R-deltamethrin

Poultry

Drinking water Cis-, trans- and alpha-R-deltamethrin Not applicable

5.0 Residue Profile

5.1 Residue Analytical Methods (860.1340)

5.1.1 Data Collection Methods

A complete method description and method validation data for the method were included in the 

submission. Bayer analyzed the samples for cis- and trans-deltamethrin. Although alpha-Rdeltamethrin is a residue of concern for both tolerance enforcement and risk assessment, Bayer 

did not report results for the alpha-R isomer. Bayer stated that residues of the alpha-R isomer 

were non-detectable in the samples that were analyzed (electronic communication from J. Brill 

(Bayer CropSciences) to D. Dotson, 10/30/2014). Bayer also stated that the alpha-R isomer is 

present in only trace amounts in the technical material and would be present in even lower 

amounts in the end-use product. In the field trials that were performed, samples were taken the 

day of application. There would be no time for conversion of the cis isomer to the alpha-R 

isomer. In the adulticide trials, samples were stored for up to 13 months. The cis isomer would 

not have converted to the trans isomer because the available storage stability data for 

deltamethrin demonstrate that the three individual isomers are stable during frozen storage.

Residues of the cis and trans isomers were extracted from plant tissues using acetone/nhexane/dichloromethane (1/1/1, v/v) as the extraction solvent. Extract cleanup was by cation 

exchange SPE and analysis was by LC-MS/MS.

Acceptable method validation recoveries of cis- and trans-deltamethrin were obtained from 

samples of alfalfa forage, alfalfa hay, leaf lettuce, grass forage, and grass hay fortified at levels 

ranging from 0.01 ppm to 0.86 ppm, as specified in the table below. Mean recoveries ranged 

from 72 to 105%.

The LOQ for cis- and trans-deltamethrin in lettuce and forage (both grass and alfalfa) was 0.01 

ppm. The LOQ for both isomers in hay (both grass and alfalfa) was 0.04 ppm. The reported 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 11 of 25

LODs ranged from 0.003 ppm to 0.02 ppm, depending on isomer and matrix.

Conclusions: The data collection method used for analysis of residues of cis-and transdeltamethrin in alfalfa forage, alfalfa hay, leaf lettuce, grass forage, and grass hay is adequate

based on acceptable method validation data.

5.1.2 Multiresidue Methods (860.1360)

Multiresidue methods data for cis-deltamethrin and trans-deltamethrin have previously been sent 

to FDA. Cis-deltamethrin is completely recovered through Methods 302 and 303, and partially 

recovered through Method 304. Trans-Deltamethrin is partially recovered through Method 303, 

but not recovered through Method 304. 

5.1.3 Tolerance Enforcement Methods

Adequate GC/ECD methods are available for enforcing tolerances for residues of deltamethrin in 

both plant and livestock commodities. A tolerance enforcement method using GC/ECD is 

available in PAM Volume II (Section 180.422) for determining residues of deltamethrin, along 

with a modified version of this method (Method ENC 8/92) for analysis of deltamethrin in plant 

commodities. 

Two other GC/ECD methods are also available for enforcing deltamethrin tolerances in plant 

commodities. Method ENC-6/92 is for determining residues in grain crops and processed 

fractions, while Method HRAV-20 is for determining residues in other food/feed crops. 

Adequate confirmatory method validation, radiovalidation and ILV data were submitted for these 

GC/ECD methods, and HED concluded that an Agency validation was not required for these 

methods. The reported LOQs for each deltamethrin isomer range from 0.005 to 0.050 ppm, 

depending on the plant commodity. 

Another GC/ECD method (Method HRAV-22) is available for enforcing tolerances in livestock

commodities. Adequate confirmatory method validation data have been submitted for this 

method, along with an adequate ILV trial. The reported LOQ for each deltamethrin isomer is 

0.005 ppm in all livestock matrices, except fat, which has an LOQ of 0.015 ppm. 

5.2 Storage Stability (860.1380)

Bayer did not submit storage stability data for the alfalfa, grass, and lettuce samples taken in the 

adulticide residue study. However, data previously submitted by Bayer indicate that residues of 

cis-, trans-, and α-R-deltamethrin are stable under frozen storage conditions for at least 3 years

in/on cottonseed and field corn grain, forage, stover, starch, flour, and oil. Each analyte was also

stable for at least 2 years in frozen tomato, 1 year in frozen apples and cucumbers, 16 months in 

lettuce, tomato puree, and tomato wet pomace. The samples taken in the adulticide trials were 

stored for a maximum of 13 months.

Conclusions: The storage stability data that have been previously submitted for deltamethrin 

demonstrate that the chemical is generally very stable under frozen storage conditions. The 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 12 of 25

storage stability data are adequate to support the frozen storage intervals of all samples from the 

current adulticide residue trials. 

5.3 Residue Data

5.3.1 Crop Field Trials (860.1500)

Bayer performed residue trials in accordance with a protocol the company submitted to 

ChemSAC in 2012. Two trials were performed in EPA Growing Zone 5. One trial was 

performed in Lenexa, Kansas, and the other trial was performed in Springfield, Nebraska. As 

ChemSAC requested, Bayer ensured the trials were independent by performing them 200 miles 

apart and used application equipment that was consistent with that specified on the label

(ground-based fogger). Residues were measured in alfalfa forage, alfalfa hay, leaf lettuce, grass 

forage, and grass hay. At each location, two plots of each commodity were treated 10 times with 

a broadcast foliar ultra low volume (ULV) spray application of an EW (emulsion in water) 

formulation of deltamethrin. One plot was treated at a 1⁄2x application rate (0.00067 lb a.i./A for 

a total application rate of 0.0067 lb ai/A) and the other at a 1x application rate (0.00134 lb a.i./A 

for a total application rate of 0.0134 lb ai/A). Applications were made at a 3-day re-treatment 

interval (RTI), and samples were collected on the same day as the last application. Duplicate 

composite samples were taken after each application at each location (both low and high rate 

plots). As there were two separate locations, four samples were taken for analysis. 

Residues were below 0.05 ppm in all samples of leaf lettuce treated at both the 1x and 1⁄2x rate. 

In grass forage, residues ranged up to 0.087 ppm in samples treated at a 1x rate. In alfalfa 

forage, residues ranged up to 0.070 ppm in samples treated at a 1x rate. Residues in alfalfa hay 

and grass hay are not being considered for tolerance-setting purposes because hay is a dried 

commodity and not representative of fresh-market commodities. In all trials, residues increased 

with an increase in number of treatments. Table 5.3.1, below, summarizes the results of the 

residue trials that were performed.
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 13 of 25

Table 5.3.1. Summary of Total Residues from Alfalfa Forage Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

Residues (ppm)

Min Max LAFT HAFT Mean SD

Alfalfa Forage: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Alfalfa 

Forage

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4 <0.004 0.0112 0.0055 0.0089 0.0073 0.00302

2

0.00067-

0.00070 0 4 0.0105 0.0148 0.0108 0.0131 0.0120 0.0020

3 0.00068 0 4 0.0084 0.0178 0.0131 0.0139 0.0135 0.00423

4

0.00066-

0.00068 0 4 0.0172 0.0208 0.0173 0.0200 0.0187 0.00144

5

0.00067-

0.00068 0 4 0.0160 0.0244 0.0202 0.0206 0.0204 0.00363

6

0.00067-

0.00069 0 4 0.0113 0.0220 0.0136 0.0209 0.0172 0.00471

7 0.00066 0 4 0.0237 0.0382 0.0249 0.0388 0.0313 0.00749

8

0.00066-

0.00068 0 4 <0.004 0.0294 0.0115 0.0281 0.0198 0.01142

9

0.00067-

0.00069 0 4 0.0165 0.0544 0.0170 0.0434 0.0302 0.0178

10 0.00067-

0.00068 0 4 0.0144 0.0441 0.0162 0.0380 0.0271 0.0136

Alfalfa Forage: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Alfalfa 

Forage

Cis and 

TransDeltamethrin

1 0.0013 0 4 <0.004 0.0075 <0.004 0.0069 0.0055 0.0018

2

0.0013-

0.0014 0 4 0.0066 0.0394 0.0075 0.0363 0.0219 0.0168

3

0.0013-

0.0014 0 4 0.0072 0.0337 0.0093 0.0294 0.0194 0.0122

4 0.0013 0 4 0.0139 0.0385 0.0147 0.0360 0.0254 0.0124

5 0.0013 0 4 0.0143 0.0507 0.0164 0.0455 0.0310 0.0174

6 0.0013 0 4 0.0122 0.0525 0.0124 0.0463 0.0293 0.0202

7 0.0013 0 4 0.0128 0.0362 0.0143 0.0324 0.0228 0.0101

8 0.0013 0 4 0.0205 0.0444 0.0290 0.0409 0.0349 0.0102

9 0.0013 0 4 0.0315 0.0696 0.0397 0.0620 0.0508 0.0158

10 0.0013 0 4 0.0040 0.0690 0.0301 0.0671 0.0343 0.0332

LAFT = Lowest Average Field Trial, HAFT = Highest Average Field Trial, SD = Standard Deviation. For computation of the 

LAFT, HAFT, median, mean, and standard deviation, values <LOQ are assumed to be at the LOQ.
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 14 of 25

Table 5.3.1. Summary of Total Residues from Alfalfa Hay Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

Residues (ppm)

Min Max LAFT HAFT Mean SD

Alfalfa Hay: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Alfalfa 

Hay

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4 <0.0150 0.0507 0.0150 0.0480 0.0316 0.0193

2

0.00067-

0.00070 0 4 0.0356 0.0885 0.0399 0.0707 0.0555 0.0233

3 0.00068 0 4 0.0340 0.0495 0.0365 0.0456 0.0413 0.0065

4

0.00066-

0.00068 0 4 0.0512 0.164 0.0548 0.1530 0.0564 0.0069

5

0.00067-

0.00068 0 4 0.0560 0.0930 0.0589 0.0805 0.0603 0.0029

6

0.00067-

0.00069 0 4 <0.015 0.0537 0.0278 0.0522 0.0400 0.0176

7 0.00066 0 4 0.0331 0.0737 0.0380 0.0716 0.0613 0.0125

8

0.00066-

0.00068 0 4 0.0350 0.0707 0.0357 0.0624 0.0480 0.0205

9

0.00067-

0.00069 0 4 <0.015 0.0709 0.015 0.0679 0.0565 0.0140

10 0.00067-

0.00068 0 4 0.0529 0.0854 0.0618 0.0848 0.0681 0.0195

Alfalfa Hay: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Alfalfa 

Hay

Cis and 

TransDeltamethrin

1 0.0013 0 4 <0.015 0.0253 0.0150 0.0213 0.0182 0.0049

2

0.0013-

0.0014 0 4 0.0354 0.0836 0.0193 0.0592 0.0393 0.0305

3

0.0013-

0.0014 0 4 0.0201 0.0687 0.0205 0.0643 0.0424 0.0255

4 0.0013 0 4 0.0305 0.0952 0.0326 0.0935 0.0631 0.0352

5 0.0013 0 4 0.0337 0.0878 0.0348 0.0736 0.0515 0.0193

6 0.0013 0 4 0.0186 0.164 0.0217 0.1410 0.0792 0.0680

7 0.0013 0 4 0.0378 0.0930 0.0391 0.0680 0.0537 0.0263

8 0.0013 0 4 0.0150 0.0832 0.0352 0.0805 0.0579 0.0314

9 0.0013 0 4 0.0333 0.1205 0.0428 0.1101 0.0765 0.0404

10 0.0013 0 4 0.0178 0.1110 0.0363 0.1110 0.0272 0.0108

LAFT = Lowest Average Field Trial, HAFT = Highest Average Field Trial, SD = Standard Deviation. For computation of the 

LAFT, HAFT, median, mean, and standard deviation, values <LOQ are assumed to be at the LOQ.
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 15 of 25

Table 5.3.1. Summary of Total Residues from Lettuce Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) N

Residues (ppm)

Min Max LAFT HAFT Mean SD

Leaf Lettuce: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Lettuce 

Leaves

Cis and 

TransDeltamethrin

1

0.00066-

0.00067 0 4 <0.0035 0.0241 0.0035 0.0234 0.0139 0.0114

2

0.00067-

0.00068 0 4 0.0163 0.0311 0.0208 0.0236 0.0225 0.0069

3

0.00067-

0.00068 0 4 0.0114 0.0408 0.0128 0.0384 0.0259 0.0150

4

0.00067-

0.00068 0 4 0.0151 0.0375 0.0165 0.0372 0.0271 0.0120

5

0.00073-

0.00066 0 4 0.0115 0.0297 0.0210 0.0225 0.0169 0.0087

6

0.00067-

0.00068 0 4 0.0073 0.0303 0.0080 0.0284 0.0185 0.0119

7 0.00067 0 4 0.0064 0.0327 0.0065 0.0290 0.0180 0.0133

8

0.00066-

0.00067 0 4 0.0059 0.0306 0.0062 0.0278 0.0172 0.0127

9

0.00067-

0.00068 0 4 0.0043 0.0349 0.0045 0.0349 0.0200 0.0175

10 0.00067-

0.00068 0 4 0.0065 0.0446 0.0080 0.0425 0.0255 0.0201

Leaf Lettuce: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Lettuce 

Leaves

Cis and 

TransDeltamethrin

1 0.0013 0 4 0.0048 0.0150 0.0051 0.0140 0.0098 0.0052

2 0.0013 0 4 0.0100 0.0234 0.0101 0.0192 0.0150 0.0063

3 0.0013 0 4 0.0100 0.0116 0.0102 0.0106 0.0107 0.0009

4 0.0013 0 4 0.0116 0.0187 0.0120 0.0168 0.0147 0.0032

5 0.0013 0 4 0.0120 0.0188 0.0122 0.0153 0.0140 0.0034

6 0.0013 0 4 0.0062 0.0089 0.0065 0.0087 0.0079 0.0014

7 0.0013 0 4 0.0060 0.0348 0.0085 0.0342 0.0213 0.0150

8 0.0013 0 4 0.0060 0.0222 0.0061 0.0202 0.0134 0.0083

9 0.0013 0 4 0.0052 0.0412 0.0057 0.0365 0.0214 0.0183

10 0.0013 0 4 0.0057 0.0375 0.0063 0.0331 0.0200 0.0158

LAFT = Lowest Average Field Trial, HAFT = Highest Average Field Trial, SD = Standard Deviation. For computation of the 

LAFT, HAFT, median, mean, and standard deviation, values <LOQ are assumed to be at the LOQ.
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 16 of 25

Table 5.3.1. Summary of Total Residues from Grass Forage Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

Residues (ppm)

Min Max LAFT HAFT Mean SD

Grass Forage: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Grass 

Forage

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4 0.0053 0.0188 0.0053 0.0149 0.0103 0.0064

2

0.00067-

0.00070 0 4 0.0093 0.0232 0.0117 0.0197 0.0159 0.0058

3

0.00067-

0.00068 0 4 0.0197 0.0330 0.0216 0.0292 0.0255 0.0055

4

0.00067-

0.00068 0 4 0.0170 0.0203 0.0174 0.0188 0.0183 0.0014

5

0.00066-

0.00067 0 4 0.0167 0.0190 0.0169 0.0189 0.0181 0.0012

6

0.00067-

0.00069 0 4 0.0132 0.0333 0.0153 0.0297 0.0226 0.0089

7 0.00066 0 4 0.0205 0.0351 0.0223 0.0316 0.0271 0.0062

8

0.00073-

0.00067 0 4 0.0282 0.0338 0.0295 0.0324 0.0310 0.0023

9

0.00066-

0.00068 0 4 0.0218 0.0308 0.0261 0.0285 0.0274 0.0043

10 0.00067 0 4 0.0251 0.0429 0.0303 0.0339 0.0321 0.0086

Grass Forage: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Grass 

Forage

Cis and 

TransDeltamethrin

1 0.0013 0 4 0.00716 0.0166 0.0076 0.0135 0.0108 0.0043

2

0.0013-

0.0014 0 4 0.0113 0.0175 0.0114 0.0157 0.0137 0.0029

3 0.0013 0 4 0.0194 0.0278 0.0202 0.0259 0.0232 0.0037

4 0.0013 0 4 0.0168 0.0250 0.0190 0.0245 0.0220 0.0037

5

0.0014-

0.0013 0 4 0.0174 0.0284 0.0192 0.0257 0.0227 0.0046

6 0.0013 0 4 0.0113 0.0320 0.0146 0.0248 0.0199 0.0086

7 0.0013 0 4 0.0215 0.0348 0.0274 0.0342 0.0309 0.0063

8 0.0013 0 4 0.0292 0.0341 0.0305 0.0317 0.0302 0.0038

9 0.0013 0 4 0.0187 0.0791 0.0222 0.0748 0.0486 0.0308

10 0.0013 0 4 0.0217 0.0870 0.0252 0.0698 0.0470 0.0295

LAFT = Lowest Average Field Trial, HAFT = Highest Average Field Trial, SD = Standard Deviation. For computation of the 

LAFT, HAFT, median, mean, and standard deviation, values <LOQ are assumed to be at the LOQ.
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 17 of 25

Table 5.3.1. Summary of Total Residues from Grass Hay Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

Residues (ppm)

Min Max LAFT HAFT Mean SD

Grass Hay: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Grass 

Hay

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4 <0.0200 0.0920 <0.02 0.0867 0.0535 0.0389

2

0.00067-

0.00070 0 4 0.0289 0.0772 0.0319 0.0772 0.0549 0.0262

3

0.00067-

0.00068 0 4 0.0390 0.0859 0.0411 0.0809 0.0613 0.0235

4

0.00067-

0.00068 0 4 0.0520 0.0876 0.0521 0.0795 0.0661 0.0171

5

0.00066-

0.00067 0 4 0.0432 0.1240 0.0461 0.122 0.0842 0.0438

6

0.00067-

0.00069 0 4 0.0537 0.0974 0.0573 0.0955 0.0767 0.0224

7 0.00066 0 4 0.0572 0.1584 0.0574 0.137 0.0974 0.0491

8

0.00073-

0.00067 0 4 0.0493 0.1340 0.0501 0.133 0.0914 0.0474

9

0.00066-

0.00068 0 4 0.0513 0.1624 0.0550 0.162 0.1087 0.0618

10 0.00067 0 4 0.0489 0.1976 0.0491 0.188 0.1188 0.0805

Grass Hay: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Grass 

Hay

Cis and 

TransDeltamethrin

1 0.0013 0 4 0.0295 0.0520 0.0298 0.0421 0.0362 0.0108

2

0.0013-

0.0014 0 4 0.0293 0.0558 0.0324 0.0555 0.0443 0.0137

3 0.0013 0 4 0.0705 0.0823 0.0712 0.0823 0.0771 0.0065

4 0.0013 0 4 0.0913 0.1280 0.0987 0.121 0.1095 0.0153

5

0.0014-

0.0013 0 4 0.0790 0.1333 0.0791 0.123 0.1011 0.0265

6 0.0013 0 4 0.0703 0.1611 0.0729 0.152 0.1124 0.0460

7 0.0013 0 4 0.0992 0.1078 0.1036 0.154 0.0640 0.0459

8 0.0013 0 4 0.1160 0.1398 0.1277 0.139 0.0753 0.0612

9 0.0013 0 4 0.1150 0.3770 0.1179 0.354 0.0851 0.0388

10 0.0013 0 4 0.1490 0.3690 0.1495 0.347 0.1116 0.0438

LAFT = Lowest Average Field Trial, HAFT = Highest Average Field Trial, SD = Standard Deviation. For computation of the 

LAFT, HAFT, median, mean, and standard deviation, values <LOQ are assumed to be at the LOQ.

Conclusions: The residue data are adequate to demonstrate that the 0.05 ppm FHE tolerance in 

effect for FHEs is adequate to cover residues that might arise from mosquito adulticide 

applications. 

HED considers the lettuce, alfalfa forage, and grass forage data to be adequate to serve as 

surrogates for all other crops. These commodities were originally selected because they are 

considered to be worst-case with respect to residue levels. They are all leafy crops with high 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 18 of 25

surface areas. Residues in lettuce were all below 0.05 ppm, even in samples treated ten times at 

a 3-day re-treatment interval. Of the 120 samples of lettuce, grass forage, and alfalfa forage, 

only ten had residues above 0.05 ppm. Eight of these samples received nine or ten treatments. 

Furthermore, HED notes that the field trials were conducted by driving the fogging truck through 

the agricultural field (i.e., application over the crop with the fog settling on the crop). Given that 

the intended application scenario is a truck-based fogger driven next to an agricultural field and

that applications will be made under low/no wind conditions, the field trial data likely reflect a 

significant overestimate of what actual residues would be on crops. 

The maximum residues in the dried commodities (grass and alfalfa hay) are only slightly higher 

than 0.05 ppm when prorated to the same dry matter as the respective forages. 

Residues found in the livestock feed items would not affect the dietary burden (as discussed in 

the Meat, Milk, Poultry, and Eggs section of this document, Section 5.3.4). Deltamethrin is 

already registered for use on a large number of crops, many of which have tolerances that exceed 

0.05 ppm.

5.3.2 Field Rotational Crops (860.1900)

A study investigating field accumulation in rotational crops has not been conducted with 

deltamethrin. A field study is not required because the confined rotational crop study indicated

that residues of deltamethrin do not accumulate in rotational crops. 

5.3.3 Processed Food and Feed (860.1520)

This guideline topic is not relevant to the proposed use of deltamethrin as a mosquito adulticide. 

5.3.4 Meat, Milk, Poultry and Eggs (860.1480)

The livestock commodity tolerances in effect for deltamethrin were established as a result of a 

risk assessment that was performed in 2004 (D281203, D. Dotson, et al., 11/12/2004). That risk 

assessment included a large number of commodities, including numerous livestock feed items. 

As part of the risk assessment, HED calculated a maximum theoretical dietary burdens for beef 

cattle, dairy cattle, swine, and poultry. Since that risk assessment was performed, HED has 

updated its procedure for calculating dietary burdens. HED now calculates maximum reasonably 

balanced dietary burdens, which are more realistic estimates of the residues to which livestock 

will be exposed. In support of the current risk assessment, HED calculated updated dietary 

burdens. In all cases, the dietary burdens decreased from the 2004 values. The dietary burdens 

decreased as follows: beef cattle: 14 ppm to 5 ppm; dairy cattle: 14 ppm to 10 ppm; poultry: 1.6 

ppm to 0.5 ppm; and swine: 1.6 ppm to 0.5 ppm. The tolerances for cattle, goat, horse, and 

sheep commodities were based primarily on residues in sweet corn forage, which has a tolerance 

of 10 ppm. The diet was comprised of sweet corn forage at a level of 45%. The tolerances for 

poultry and swine commodities were based primarily on residues in wheat milled byproducts, 

which have a tolerance of 1.0 ppm. The poultry and swine diets included wheat milled

byproducts at a level of 50%. Inadvertent residues in any livestock feed items that result from 

the adulticide use of deltamethrin will not increase the dietary burdens to levels that exceed the 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 19 of 25

levels that were used to determine the original dietary burdens. The data used in determining the 

updated reasonably balanced dietary burdens are provided in Table 5.3.4, below. 

Table 5.3.4. Calculation of Dietary Burdens of Deltamethrin Residues to Livestock

Feedstuff Type1 % Dry 

Matter2 % Diet2 Tolerance Residue Level (ppm)

Dietary 

Contribution 

(ppm)3

Beef Cattle (R = 15%; CC = 80%; PC = 5%)

Aspirated Grain Fractions CC 85 5 65 76.4 3.824

Field Corn Stover R 83 15 5.0 6.02 0.903

Wheat Milled Byproducts CC 88 40 1.0 1.136 0.454

Potato Processed Waste CC 15 30 0.04 0.267 0.080

Canola Meal PC 88 5 0.2 0.227 0.0114

Potato Culls CC 20 5 0.04 0.200 0.01

TOTAL BURDEN -- -- -- 5.3

Dairy Cattle (R = 45%; CC = 45%; RC = 10%)

Sweet Corn Forage R 48 45 10 20.8 9.36

Wheat Milled Byproducts CC 88 25 1.0 1.136 0.284

Wet Apple Pomace CC 40 10 1.0 2.5 0.25

Carrot Culls CC 12 10 0.2 1.667 0.117

Canola Meal PC 88 10 0.2 0.227 0.0227

TOTAL BURDEN -- -- -- 10

Swine (CC = 85%; PC = 15%)

Wheat Milled Byproducts CC NA 50 1.0 1.0 0.50

Canola Meal PC NA 15 0.2 0.2 0.03

TOTAL BURDEN -- -- -- 0.53

Poultry (CC = 75%; PC = 25%)

Wheat Milled Byproducts CC NA 50 1.0 1.0 0.50

Canola Meal PC NA 15 0.2 0.2 0.03

Soybean Seed PC NA 10 0.1 0.1 0.01

TOTAL BURDEN -- -- -- 0.54

1 R: Roughage; CC: Carbohydrate concentrate; PC: Protein concentrate.

2 Table 1 Feedstuffs (July 2008). 

3 Contribution = ([tolerance /% DM] X % diet) for beef and dairy cattle; contribution = ([tolerance] X % diet) for 

poultry and swine.

The most current guidance for calculation of dietary burdens permits the use of the HAFT for 

nonblended livestock feed items and the median residue value for blended livestock feed items. 

Using the HAFT and median residue values in place of the tolerances would decrease the current 

maximum reasonably balanced diets to an even greater extent.

Conclusions: The current livestock commodity tolerances were determined using a method 

based on very conservative assumptions that provide overestimates of residues that are likely to 

occur in livestock commodities. Inadvertent residues in any livestock feed items that result from 

the adulticide use of deltamethrin will not increase the dietary burdens to levels that exceed the 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 20 of 25

levels that were used to determine the original dietary burdens. Increased tolerances are not 

needed.

5.3.5 Food Handling (860.1460)

Although Bayer is proposing that the 0.05 ppm food handling establishment tolerance cover the 

mosquito adulticide use, this guideline topic is not relevant to the current petition for any other 

reason. 

5.3.6 Water, Fish, and Irrigated Crops (860.1400)

In order to be efficacious as a mosquito adulticide, deltamethrin applications will be made with 

the use of a ULV fogger that emits particles in a size range that will maximize their ability to 

remain suspended in air. As a result, residues are not expected to occur in water bodies, fish, and 

irrigated crops. For this reason, this guideline topic is not relevant to the current tolerance 

petition.

5.4 Food Residue Profile

The adulticide trials that were performed demonstrate that deltamethrin residues are expected to 

occur at low levels in food commodities, if at all. HED considers the submitted data to be 

adequate to demonstrate that the 0.05 ppm FHE tolerance covers the adulticide use. 

6.0 Tolerance Derivation

The existing established tolerance for deltamethrin residues of 0.05 ppm in/on all food 

commodities, arising from use of the insecticide in food handling establishments, is also 

adequate to cover residues arising from the proposed use in the vicinity of, or the airspace above, 

agricultural field crops. Residues in samples demonstrate that the tolerance of 0.05 ppm will not 

be exceeded as a result of the adulticide use.

HED recommends that the tolerance expression for deltamethrin, cited under 40CFR 

§180.435[a][2], be amended to read as follows: 

A tolerance of 0.05 ppm is established for residues of the insecticide deltamethrin, 

including its metabolites and degradates, in or on all raw agricultural commodities 

and processed food or feed from use of deltamethrin in food or feed handling 

establishments where food/feed and food/feed products are held, processed, 

prepared and/or served, or as a wide-area mosquito adulticide. Compliance with 

the tolerance level specified is to be determined by measuring only deltamethrin 

[(1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylic acid (S)-

alpha-cyano-3-phenoxybenzyl ester], and its major metabolites, trans

deltamethrin [(S)-alpha-cyano-m-phenoxybenzyl(1R,3S)-3-(2,2-dibromovinyl)-

2,2-dimethylcyclopropanecarboxylate] and alpha-R-deltamethrin [(R)-alphacyano-m-phenoxybenzyl-(1R,3R)-3-(2,2-dibromovinyl)-2,2-

dimethylcyclopropanecarboxylate] in or on the commodity. 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 21 of 25

Codex and Canada have established MRLs for residues of deltamethrin in/on numerous

commodities. An International Residue Limit Status sheet is appended as Attachment 1. As the 

proposed tolerance applies to all commodities, the MRL status sheet includes all commodities

with deltamethrin tolerances. It also includes commodities for which there is no U.S. equivalent.

References

Deltamethrin. Petition to Establish Permanent Tolerances (Without U.S. Section 3 Registration) 

for Residues Resulting from Use of the Insecticide on Imported Finfish. Summary of Analytical 

Chemistry and Residue Data, D413135, W. Drew, 6/17/2014

MRID 49114112. M. Krolski (2013) Magnitude of the Residue in/on Alfalfa, Leaf Lettuce, and 

Grass Following Ultra Low Volume (ULV) Spray for Mosquito Control. Study Number: 

RADAN008. Unpublished study prepared by Bayer CropScience. 788 pages, D423045, D. 

Dotson, 12/4/2014.

PP#s 0F6080 and 1E6232: Tolerance Petition for the Use of Deltamethrin on Various Crops, 

Summary of Residue Chemistry and Analytical Methods, D281203, D. Dotson, 11/12/2004

PP#s 0F6080 and 1E6232: Human Health Risk Assessment for the Proposed Section 3 Uses of 

Deltamethrin on Various Crops and Residential Scenarios; D262496; D. Dotson; 11/15/2004

Deltamethrin. Human Health Risk Assessment for the Proposed Use of Deltamethrin Without 

U.S. Registration on Finfish, D413048, D. Dotson, et al., 10/10/2014

MARC Decision Memo; D286801; D. Dotson, N. McCarroll; 14 January 2003. 

Tier I Estimated Drinking Water Concentrations of Deltamethrin for the Use in the Human 

Health Risk Assessment: IR-4 Tolerance Petition for the Use of Deltamethrin on Flax; 

D335136; J. Melendez; 24 April 2007.

Tiers I and II Estimated Drinking Waters Concentrations for Deltamethrin for the New Use as an 

Adulticide for the Product BES0668 Insecticide, (PC Code 097805; DP Barcode D417559), J. 

Melendez, 10/9/2014 

Revisions of Feedstuffs in Table 1 of OPPTS Test Guideline 860.1000 and Guidance on 

Constructing Maximum Reasonably Balanced Diets (MRBD); ChemSAC; 30 June 2008. 

Attachments

Attachment 1: International Residue Limit Status sheet. 
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 22 of 25

Attachment 1: Deltamethrin International Residue Limit Status

Summary of US and International Tolerances and Maximum Residue Limits 

Residue Definition: 

US Canada Mexico1 Codex2

40 CFR 180.435 

Plants/Livestock: 

Deltamethrin [(1R,3R)-

3-(2,2-dibromovinyl)-

2,2-dimethylcyclopropanecarboxylic 

acid (S)-alpha-cyano-3-

phenoxybenzyl ester], 

and its major 

metabolites, trans

deltamethrin [(S)-alphacyano-m-phenoxybenzyl 

(1R,3S)-3-(2,2-

dibromovinyl)-2,2-

dimethylcyclopropaneca

rboxylate] and alpha-Rdeltamethrin [(R)-alphacyano-mphenoxybenzyl-(1R,3R)-

3-(2,2-dibromovinyl)-

2,2-dimethylcyclopropanecarboxylate] 

All commodities (except milk):

cyclopropanecarboxylic acid, 3-(2,2-

dibromoethenyl)-2,2-dimethyl-, (S)-

cyano(3-phenoxyphenyl)methyl ester, 

(1R,3R)-, including the isomers 

cyclopropanecarboxylic acid, 3-(2,2-

dibromoethenyl)-2,2-dimethyl-, (S)-

cyano(3-phenoxyphenyl)methyl ester, 

(1R,3S)- and cyclopropanecarboxylic 

acid, 3-(2,2-dibromoethenyl)-2,2-

dimethyl-, (R)-cyano(3-

phenoxyphenyl)methyl ester, (1R,3R)-

Milk: cyclopropanecarboxylic acid, 3-

(2,2-dibromoethenyl)-2,2-dimethyl-, 

(S)-cyano(3-phenoxyphenyl)methyl 

ester, (1R,3R)-, including the isomers 

cyclopropanecarboxylic acid, 3-(2,2-

dibromoethenyl)-2,2-dimethyl-, (S)-

cyano(3-phenoxyphenyl)methyl ester, 

(1R,3S)- and cyclopropanecarboxylic 

acid, 3-(2,2-dibromoethenyl)-2,2-

dimethyl-, (R)-cyano(3-

phenoxyphenyl)methyl ester, (1R,3R)-

(calculated on the fat content)

Sum of deltamethrin, 

alpha-R- and transdeltamethrin (1R-

[1alpha(R*),3alpha]]-

3-(2,2-

dibromoethenyl)-2,2-

dimethylcyclopropanecarboxyl

ic acid, cyano(3-

phenoxyphenyl)meth

yl ester and [1R-

[1alpha(S*),3beta]]-

3-(2,2-

dibromoethenyl)-2,2-

dimethylcyclopropanecarboxyl

ic acid, cyano(3-

phenoxyphenyl)meth

yl ester) 

(fat-soluble) 

Commodity Tolerance (ppm) /Maximum Residue Limit (mg/kg)

US Canada Mexico1 Codex2

Almond, hulls 2.5

Apple, wet pomace 1.0

Artichoke, globe 0.5

Barley, bran 5.0

Cattle, fat 0.05 0.05

Cattle meat 0.02

0.02 0.5 (fat) meat (from 

mammals other than 

marine mammals)

3

Cattle, meat byproducts 0.05 0.02 0.03 (*) kidney and 

liver of cattle

Corn, field, forage 0.7

Corn, field, refined oil 2.5

Corn, field, stover 5.0

Corn, pop, stover 5.0

Corn, sweet, forage 10

Corn, sweet, kernel plus cob 

with husks removed 0.03 0.02 (*) sweet corn (corn on-the-cob)

Corn, sweet, stover 15

Cotton, refined oil 0.2
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 23 of 25

Commodity Tolerance (ppm) /Maximum Residue Limit (mg/kg)

US Canada Mexico1 Codex2

Cotton, undelinted seed 0.04

Egg 0.02 0.02 0.02 (*)

Fruit, pome, group 11 0.2 0.2 apple

Goat, fat 0.05 0.05

Goat, meat 0.02

0.02 0.5 (fat) meat (from 

mammals other than 

marine mammals) 3

Goat, meat byproducts 0.05 0.02 0.03 (*) kidney and 

liver of goats

Grain, aspirated fractions 65

Grain, cereal, Group 15, 

except sweet corn 1.0 2 Po cereal grains

Hog, fat 0.05 0.05

Horse, fat 0.05 0.05

Horse, meat 0.02

0.02 0.5 (fat) meat (from 

mammals other than 

marine mammals) 3

Horse, meat byproducts 0.05 0.02

Lychee4 0.2

Milk, fat (reflecting 0.02 ppm 

in whole milk) 0.1 0.05 milk 0.05 F milks

Nut, tree, Group 14 0.1 0.02 (*) hazelnuts, 

walnuts

Onion, bulb 0.1 0.05

Onion, green 1.5

Poultry, fat 0.05 0.05

Poultry, meat 0.02 0.02 0.1 (fat)

Poultry, meat byproducts 0.02 0.02 0.02 (*)

Radish, tops 4.0 0.01 (*) radish

Rapeseed 0.2 0.2

Rice, hulls 2.5

Rye, bran 5.0

Sheep, fat 0.05 0.05

Sheep, meat 0.02

0.02 0.5 (fat) meat (from 

mammals other than 

marine mammals) 3

Sheep, meat byproducts 0.05 0.02 0.03 (*) kidney and 

liver of sheep

Sorghum, grain, forage 0.5

Sorghum, grain, stover 1.0

Soybean, seed 0.1 0.1

Soybean, hulls 0.2

Starfruit4 0.2

Sunflower, seed 0.1 0.05 (*)

Tomato 0.2 0.3 0.3 tomato

Tomato, paste 1.0

Tomato, puree 1.0

Vegetable, cucurbit, Group 9 0.2 0.2 fruiting 

vegetables, cucurbits
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 24 of 25

Commodity Tolerance (ppm) /Maximum Residue Limit (mg/kg)

US Canada Mexico1 Codex2

Vegetable, fruiting, Group 8 0.3

0.3 African eggplants, 

bell peppers, bush 

tomatoes, coconas, 

currant tomatoes, 

eggplants, garden 

huckleberries, goji 

berries, groundcherries, 

martynias, naranjillas, 

nonbell peppers, okras, 

pea eggplants, pepinos, 

roselles, scarlet 

eggplants, sunberries,

tomatillos, tomatoes, 

tree tomatoes

0.3 tomato

Vegetable, root, except sugar 

beet, Subgroup 1B 0.2 0.02 carrot

Vegetable, tuberous and corm, 

Subgroup 1C 0.04 0.04 potato 0.01 (*) potato 

Wheat, bran 5.0 5 PoP wheat bran, 

unprocessed

MRLs with NO US Equivalent

Citrus fruits 0.02

Flowerhead brassicas 

(includes broccoli: broccoli, 

Chinese and cauliflower

0.1

Grapes 0.2

Hog, meat

0.02 0.5 (fat) meat (from 

mammals other than 

marine mammals) 3

Hog, meat byproducts 0.02 0.03 (*) kidney and 

liver of pigs 

Leafy vegetables 2

Leek 0.2

Legume vegetables 0.2

Mushrooms 0.05 F

Nectarine 0.05 

Olives 1 1

Peach 0.05

Plums (including prunes) 0.05

Pulses 1 Po

Spices, fruits and berries 0.03

Spices, roots and rhizomes 0.5

Strawberry 0.2

Tea, green, black (black, 

fermented and dried)

5

Wheat flour 0.3 PoP

Wheat wholemeal 2 PoP

Broccoli, Brussels sprouts,

cabbages, cauliflowers,

Chinese broccoli, Chinese 

mustard cabbages, kohlrabies, 

napa Chinese cabbages

3.5
Deltamethrin Summary of Analytical Chemistry and Residue Data DP Barcode D423045

Page 25 of 25

Commodity Tolerance (ppm) /Maximum Residue Limit (mg/kg)

US Canada Mexico1 Codex2

Seeds (Borage, cuphea, 

echium, flax seed, gold of 

pleasure, hare's ear mustard, 

milkweed, mustard seed (oil 

seed type), oil radish, poppy 

seed, rapeseeds (canola), 

sesame, sweet rocket

0.2

Completed: M. Negussie; 10/07/14

1 Mexico adopts US tolerances and/or Codex MRLs for its export purposes.

2* = absent at the limit of quantitation; Po = postharvest treatment, such as treatment of stored grains. PoP = 

processed postharvest treated commodity, such as processing of treated stored wheat. (fat) = to be measured on the 

fat portion of the sample. MRLs indicated as proposed have not been finalized by the CCPR and the CAC.

3 MRL accommodates external animal treatment.

4There are no U.S. registrations for use of deltamethrin on starfruit and lychee.

(2) A tolerance of 0.05 ppm is established for residues of the insecticide deltamethrin (1R,3R)-3-(2,2-

dibromovinyl)-2,2-dimethylcyclopropanecarboxylic acid (S)-alpha-cyano-3-phenoxybenzyl ester and its 

major metabolites, trans deltamethrin (S)-alpha-cyano-m-phenoxybenzyl-(1R,3R)-3-(2,2-dibromovinyl)-

2,2-dimethylcyclopropanecarboxylate and alpha-R-deltamethrin[(R)-alpha-cyano-m-phenoxybenzyl-

(1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate] as follows:

(i) In or on all food/feed items (other than those covered by a higher tolerance as a result of use on 

growing crops) in food/feed handling establishments.
I Deltamethrin!PC Code 097805/Bayer ~ropSci~nce 

==:- 1 OCSPP 860.1500/0ECD IIA 6.3.1, 6 . .;,.2, 6.3 . .;, and lilA 8.3.1, 8.3.2, 8.3.3 

Crop Field Trials - Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves) 

Primary Evaluator ..&. J~ Date: 12/4/2014 

Douglas Dotson, Ph.D., Chemist, HED/RAB2 

Peer Reviewer ~~ · Date: 12/4/2014 

Michael DohertY:Ph:I:.Chemist, HED/RAB2 

STUDY REPORT 

MRID 49114112. M. Krolski (2013) Magnitude of the Residue inion Alfalfa, Leaf Lettuce, and 

Grass Following Ultra Low Volume (ULV) Spray for Mosquito Control. Study Number: 

RADAN008. Unpublished study prepared by Bayer CropScience. 788 pages. 

EXECUTIVE SUMMARY 

Bayer Environmental Science submitted field trial data for deltamethrin on alfalfa, grass, and 

leaf lettuce. Bayer performed two trials for each crop. The trials were conducted in the U.S. 

during the 2012 growing season in NAFTA Growing Zone 5. One trial was performed in 

Springfield, Nebraska and the other trial was performed in Lenexa, Kansas. At each trial 

location, 10 broadcast foliar ultra-low volume (UL V) spray applications of deltamethrin EW 

(BES0668, Eagle Adulticide) were made. Deltamethrin EW is an evaporation-retarded 

formulation containing 20 g deltamethrin/L. 

Bayer performed the residue trials in accordance with a protocol that was previously approved by 

HED's Chemistry Science Advisory Council (ChemSAC) and submitted a report of the results 

(MRID 49114112). As ChemSAC requested, Bayer ensured the trials were independent by 

performing them 200 miles apart and used application equipment that was consistent with that 

specified on the label. Residues were measured in alfalfa forage, alfalfa hay, leaf lettuce, grass 

forage, and grass hay. At each location, two plots of each commodity were treated I 0 times at a 

3-day re-treatment interval (RTI). One plot was treated at a Ylx application rate (0.00067 lb 

a.i./A for a total seasonal application rate of0.0067 lb ai/A) and the other was performed at a 1x 

application rate (0.00134lb a.i./A for a total seasonal application rate of0.0134 lb ai/A). In each 

trial, two samples were taken for analysis immediately after each application. 

Bayer analyzed the samples for cis- and trans-deltamethrin. Although alpha-R-deltamethrin is a 

residue of concern for both tolerance enforcement and risk assessment, Bayer did not report 

results for the alpha-R isomer. Bayer stated that residues of the alpha-R isomer were nondetectable in the samples that were analyzed. Bayer also stated that the alpha-R isomer is 

present in only trace amounts in the technical material and would be present in even lower 

amounts in the end-use product. In the field trials that were performed, samples were taken the 

day of application. There would be no time for conversion of the cis isomer to the alpha-R 

Isomer. 

In all of the trials that were performed, residues increased with number of applications. In 

samples of alfalfa forage treated at the Ylx application rate, residues ranged up to 0.054 ppm (9 

applications). The highest of the highest average field trial (HAFT) values was 0.043 ppm. In 

DP Barcode 0 423045/MRID #49114112 Page I of24 
Deltamethrin/PC Code 097805/Bayer CropScience 

OCSPP 860.1500/0ECD IIA 6.3.1 , 6.3.2, 6.3.3 and IliA 8.3.1, 8.3.2, 8.3.3 

Crop Field Trials - Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves) 

samples treated at the lx application rate, residues ranged up to 0.070 ppm (9 applications). The 

highest HAFT value was 0.067 ppm. In samples of alfalfa hay treated at the 'l-2x application rate, 

residues ranged up to 0.16 ppm (4 applications). The highest HAFT value was 0.15 ppm. In 

samples treated at the lx application rate, residues ranged up to 0.16 ppm (6 applications). The 

highest HAFT value was 0.14 ppm. In samples of grass forage treated at the Y2x application rate, 

residues ranged up to 0.043 ppm (1 0 applications). The highest HAFT value was 0.034 ppm. In 

samples treated at the 1 x application rate, residues ranged up to 0.087 ppm (1 0 applications). 

The highest HAFT value was 0.075 ppm. In samples of grass hay treated at the Y2x application 

rate, residues ranged up to 0.20 ppm (1 0 applications). The highest HAFT value was 0.19 ppm. 

In samples treated at the 1 x application rate, residues ranged up to 0.38 ppm (9 applications). 

The highest HAFT value was 0.36 ppm. In samples ofleaflettuce treated at the Y2x application 

rate, residues ranged up to 0.045 ppm (10 applications). The highest HAFT value was 0.043 

ppm. In samples treated at the lx application rate, residues ranged up to 0.041 ppm (9 

applications). The highest HAFT value was 0.037 ppm. The residue data are supported by 

adequate method validation and storage stability data. 

STUDY/WAIVERACCEPTABILITYIDEFICIENCIES/CLARIFICATIONS 

Under the conditions and parameters used in the study, the alfalfa, grass and leaf lettuce field 

trial residue data are classified as scientifically acceptable. The acceptability of this study for 

regulatory purposes is addressed in the US EPA Residue Chemistry Summary Document, 

D423045 (D. Dotson, 12/4/20 14). 

COMPLIANCE 

Signed and dated Good Laboratory Practice (GLP), Quality Assurance, and Data Confidentiality 

statements were provided. No deviations from regulatory requirements were reported which 

would have an impact on the validity of the study. 

A. BACKGROUND INFORMATION 

Deltamethrin (with CAS registry number 52918-63-5, and CAS name (1R,3R)-R-cyano(3-

phenoxyphenyl)methyl 3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylate) is a 

broad-spectrum pyrethroid insecticide that is registered in the US for direct application to a wide 

variety of food/feed crops and for use on stored grains. In addition, deltamethrin is registered for 

use in food/feed handling establishments (FHEs), and a tolerance of 0.05 ppm is established for 

this use. The registrant, Bayer Environmental Science, petitioned the Agency to amend 40CFR 

§ 180.435(a)(2) to include the use of deltamethrin as a wide-area mosquito adulticide in the 

airspace over agricultural crops and proposed that the 0.05 ppm tolerance apply to the adulticide 

use as well. 

Tolerances are established for the combined residues of deltamethrin and its major metabolites 

(trans-deltamethrin and a/pha-R-deltamethrin) inion plant commodities at levels ranging from 

0.03 ppm in sweet com ears (K+CWHR) to 65 ppm in aspirated grain fractions (40 CFR 

DP Barcode 0423045/MR.ID #49114112 Page 2 of24 
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 3 of 24

§180.435[a][1]). Tolerances have also been established for residues in livestock commodities. 

Deltamethrin residues of concern (ROCs) are comprised of the active ingredient (ai), cisdeltamethrin, along with its isomeric metabolites, trans-deltamethrin and alpha-R-deltamethrin. 

The chemical structure and nomenclature of deltamethrin are listed in Table A.1, and the 

physicochemical properties of deltamethrin are presented in Table A.2, below.

Table A.1. Test Compound Nomenclature

Compound Chemical Structure

 

Common Name Cis-deltamethrin

Molecular Formula C22H19Br2NO3

Molecular Weight 505.24

Company Experimental Name AEF108569

IUPAC Name (S)-α-cyano-3-phenoxybenzyl (1R,3R)-3-(2,2-dibromovinyl)-2,2-

dimethylcyclopropanecarboxylate

CAS Name (1R,3R)-R-cyano(3-phenoxyphenyl)methyl 3-(2,2-dibromoethenyl)-2,2-

dimethylcyclopropanecarboxylate

CAS Number 52918-63-5

End-use Products (EPs) AlphaMax (No current EPA registration); AMX (No current EPA registration). 

3.2 Physicochemical Characteristics

Table A.2. Physicochemical Properties of Technical Grade Deltamethrin.*

Parameter Value

Melting Point/Range (°C) 100-102

pH Not available

Density (g/cm3at 25°C) 0.550

Water Solubility (ug/L at 25°C) <0.2

Solvent Solubility (% by weight at 20oC) Acetone 33

Alcohol 0.6

Isopropanol 0.2

Ethyl acetate 25

n-Hexane 0.2

Toluene 23

DMF 38

Dioxane 39

Vapor Pressure (mm Hg at 25oC) [mPa at 25°C] 1.5 x 10-8[1.24 x 10-5]

Dissociation Constant, pKa Does not dissociate.

Octanol/Water Partition Coefficient, KOW (at 25oC) 2.7 x 105

UV/Visible Absorption Spectrum Not available.

* Reference: MARC Briefing Memorandum; D284320; D. Dotson; 5 November 2002. 

O

O

H

O

Br

Br NC
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 4 of 24

Deltamethrin is a solid under ambient conditions, and it has low volatility. The compound has a 

very low solubility in water, and low to high solubility in organic solvents. Its octanol/water 

partition coefficient suggests that accumulation in fatty tissues is possible. 

B. EXPERIMENTAL DESIGN

B.1. Study Site Information

Bayer performed residue trials in accordance with a protocol the company submitted to 

ChemSAC in 2012. Two trials were performed in EPA Growing Zone 5. One trial was 

performed in Lenexa, Kansas, and the other trial was performed in Springfield, Nebraska. As 

ChemSAC requested, Bayer ensured the trials were independent by performing them 200 miles 

apart and used application equipment that was consistent with that specified on the label (i.e., 

truck-based fogger). Residues were measured in alfalfa forage, alfalfa hay, leaf lettuce, grass 

forage, and grass hay. At each location, two plots of each commodity were treated 10 times with 

a broadcast foliar ULV spray application of an EW (emulsion in water) formulation of 

deltamethrin. All applications were made using ground-based fogging equipment that produced 

droplets less than 20 microns in diameter. Adjuvants were not used in any of the trials.

One plot was treated at a 1⁄2x application rate (0.00067 lb a.i./A for a total seasonal application 

rate of 0.0067 lb ai/A) and the other was treated at a 1x application rate (0.00134 lb a.i./A for a 

total seasonal application rate of 0.0134 lb ai/A). Applications were made directly in the field at 

a 3-day re-treatment interval (RTI), and samples were collected on the same day as the last 

application. Duplicate composite samples were taken after each application at each location 

(both low and high rate plots). As there were two separate locations, four samples were taken for 

analysis. The study use pattern is presented in Table B.1.1, below.

TABLE B.1.1 Study Use Pattern.

Trial (City, State;

Year [Crop])

EP1 Application Information Adjuvants

Method; Timing Volume 

(GPA)2

Total Rate

(lb ai/A)

Lenexa, KS; 2012

[Alfalfa]

BES0668 Broadcast foliar, ULV mister,

1

st app: BBCH 55-63, 3-day RTI

0.053 0.0075 None

Lenexa, KS; 2012

[Grass]

BES0668 Broadcast foliar, ULV mister,

1

st app: BBCH 25-63, 3-day RTI

0.053 0.0075 None

Lenexa, KS; 2012

[Lettuce]

BES0668 Broadcast foliar, ULV mister,

1

st app: BBCH 13-16, 3-day RTI

0.053 0.0075 None

Springfield, NE; 2012

[Alfalfa]

BES0668 Broadcast foliar, ULV mister,

1

st app: BBCH 55-63, 3-day RTI

0.053 0.015 None

Springfield, NE; 2012

[Grass]

BES0668 Broadcast foliar, ULV mister,

1

st app: BBCH 25-63, 3-day RTI

0.053 0.015 None

Springfield, NE; 2012 

[Lettuce]

BES0668 Broadcast foliar, ULV mister,

1

st app: BBCH 13-16, 3-day RTI

0.053 0.015 None

1. EP = End-use Product; 0.17 lb ai/gal BES0668 Insecticide

2. GPA = Gallons Per Acre. 
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 5 of 24

B.2. Sample Handling and Preparation

At each sampling interval, duplicate composite samples (two separate runs through the plot) of 

alfalfa raw agricultural commodities of forage and hay were harvested from the treated plots. 

Similarly, duplicate composite samples (two separate runs through the plot) of leaf lettuce 

leaves, and the grass RACs of forage and hay were harvested from the treated plots. Single 

composite samples of alfalfa forage, alfalfa hay, leaf lettuce leaves, grass forage, and grass hay 

were harvested from one of the plots prior to the first application to provide control matrices.

Each composite sample of alfalfa forage, alfalfa hay, leaf lettuce leaves, grass forage, and grass 

hay contained a minimum of 0.50 kg of sample collected from at least 12 individual plants (or 

areas of the plot). Composite samples were placed into labeled (study number and sample 

number) containers for shipment. All samples were frozen within 4 hours of collection and 

remained frozen until receipt at Bayer Research 

B.3. Analytical Methodology

Bayer analyzed the samples for cis- and trans-deltamethrin. Although alpha-R-deltamethrin is a 

residue of concern for both tolerance enforcement and risk assessment, Bayer did not report 

results for the alpha-R isomer. Bayer stated that residues of the alpha-R isomer were nondetectable in the samples that were analyzed (electronic communication from J. Brill (Bayer 

CropSciences) to D. Dotson, 10/30/2014). Bayer also stated that the alpha-R isomer is present in 

only trace amounts in the technical material and would be present in even lower amounts in the 

end-use product. In the field trials that were performed, samples were taken the day of 

application. There would be no time for conversion of the cis isomer to the alpha-R isomer.

A complete method description and method validation data for the method were included in the 

submission. Residues of deltamethrin (cis and trans isomers) were extracted from homogenous 

10 g samples of alfalfa forage, lettuce leaves, and grass forage using acetone/n-hexane/

dichloromethane (1/1/1, v/v) as the extraction solvent. After evaporation of the organic phase to 

dryness, the dry residue was taken up with toluene. An aliquot of the toluene extract was 

concentrated to dryness and dissolved in dichloromethane/acetone (3/1, v/v), followed by solid 

phase extraction (SPE) clean-up with Varian MEGA BE SCX-2 GM cartridges. The extracts 

were again concentrated to dryness and dissolved in a solution of internal standard (IS) and 

aqueous acetonitrile/10 mM ammonium acetate (9/1, v/v) before analysis by LC-MS/MS.

Homogenous 5 gram samples of alfalfa hay and grass hay were soaked in water over night prior 

to extraction. Residues of cis-deltamethrin and trans-deltamethrin were extracted using 

acetone/n-hexane/dichloromethane (1/1/1,v/v) as the extraction solvent. Samples were sonicated 

and shaken twice, then filtered before an internal standard solution was added. After evaporation 

of the organic phase to dryness, the dry residue was taken up with toluene. An aliquot of the 

toluene extract was concentrated to dryness and dissolved in dichloromethane/acetone (3/1, v/v), 

followed by SPE clean-up with Varian MEGA BE SCX-2 GM cartridges. The extracts were 

again concentrated to dryness and dissolved in aqueous acetonitrile/10 mM ammonium acetate 
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 6 of 24

(9/1, v/v) before analysis by LC-MS/MS. HPLC separation was performed with an Ascentis 

Express C18, 2.7 μm, 150 mm x 3 mm HPLC column.

Quantitation of each analyte was based on the daughter ion transitions of the analyte and the 

respective internal standard analog. The response of the LC-MS/MS system to each analyte and 

its internal standard was measured in samples and in standards, and a relative response was 

calculated (calculated as the ratio of the analyte and the stable isotopically labeled internal 

standard responses). The relative response of the analyte in each sample was compared to the 

relative response of the analyte in the standards.

The relative responses of cis-deltamethrin and trans-deltamethrin in solvent were measured over 

the ranges of 0.0025 ppm to 0.20 ppm in alfalfa forage, leaf lettuce, and grass forage, and 0.005 

ppm to 0.40 ppm in alfalfa hay and grass hay. The correlation coefficients were calculated using 

linear regression analysis with 1/x weighting. The total deltamethrin residue is the sum of the 

individual measured residue of cis-deltamethrin and trans-deltamethrin (in parent equivalents).

The method for determining cis-deltamethrin and trans-deltamethrin residues in/on alfalfa 

forage, alfalfa hay, leaf lettuce, grass forage, and grass hay were validated by measuring the 

recovery of these analytes from control matrices fortified at their respective LOQs. Additional 

recoveries at higher fortification levels validated the method for the highest residues observed in 

individual matrices. Concurrent recoveries of cis-deltamethrin and trans-deltamethrin from 

alfalfa forage, alfalfa hay, leaf lettuce, grass forage, and grass hay were measured with each set 

of samples to verify method performance.

C. RESULTS AND DISCUSSION

Acceptable method validation recoveries of cis- and trans-deltamethrin were obtained from 

samples of alfalfa forage, alfalfa hay, leaf lettuce, grass forage, and grass hay fortified at levels 

ranging from 0.01 ppm to 0.86 ppm, as specified in Table C.1, below. Mean recoveries ranged 

from 72 to 105%.

The LOQ for cis- and trans-deltamethrin in lettuce and forage (both grass and alfalfa) was 0.01 

ppm. The LOQ for both isomers in hay (both grass and alfalfa) was 0.04 ppm. The reported 

LODs ranged from 0.003 ppm to 0.02 ppm, depending on isomer and matrix.

The analytical method was determined to be adequate for use in data collection for this study, 

based on method validation and concurrent recovery results. In all of the trials that were 

performed, residues increased with number of applications. Results of the individual trials are as 

follows. 

Alfalfa Forage: In samples treated at the 1⁄2x application rate, residues ranged up to 0.054 ppm (9 

applications). The highest HAFT value was 0.043 ppm. In samples treated at the 1x application 

rate, residues ranged up to 0.070 ppm (9 applications). The highest HAFT value was 0.067 ppm. 
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 7 of 24

Alfalfa Hay: In samples treated at the 1⁄2x application rate, residues ranged up to 0.16 ppm (4

applications). The highest HAFT value was 0.15 ppm. In samples treated at the 1x application 

rate, residues ranged up to 0.16 ppm (6 applications). The highest HAFT value was 0.14 ppm.

Grass Forage: In samples treated at the 1⁄2x application rate, residues ranged up to 0.043 ppm (10 

applications). The highest HAFT value was 0.034 ppm. In samples treated at the 1x application 

rate, residues ranged up to 0.087 ppm (10 applications). The highest HAFT value was 0.075 

ppm. 

Grass Hay: In samples treated at the 1⁄2x application rate, residues ranged up to 0.20 ppm (10 

applications). The highest HAFT value was 0.19 ppm. In samples treated at the 1x application 

rate, residues ranged up to 0.38 ppm (9 applications). The highest HAFT value was 0.36 ppm. 

Leaf Lettuce: In samples treated at the 1⁄2x application rate, residues ranged up to 0.045 ppm (10 

applications). The highest HAFT value was 0.043 ppm. In samples treated at the 1x application 

rate, residues ranged up to 0.041 ppm (9 applications). The highest HAFT value was 0.037 ppm.

Table C.1. Recovery Results from Method Validation of Alfalfa, Lettuce, and Grass Using the Data 

Collection Analytical Method. 

Matrix Spiking 

Level 

(ppm)

No. of 

Samples

Recoveries Obtained (%) Mean 

Recovery 

(%)

Standard 

Deviation 

(%)

Alfalfa Forage

Cis-deltamethrin 0.01 16 103, 125, 107, 112, 111, 101, 103, 74, 76, 74, 74, 

78, 83, 103, 97, 98

95 16

0.07 3 84, 80, 73 79 5.4

Transdeltamethrin0.01 16 80, 83, 99, 115, 101, 91, 106, 104, 90, 90, 92, 122, 

86, 91, 84, 84

95 12

0.07 3 90, 86, 82 86 4.2

Alfalfa Hay

Cis-deltamethrin 0.04 15 77, 89, 91, 96, 86, 97, 85, 87, 85, 85, 110, 79, 89, 

107, 91

90 9.0

0.5 2 70, 83 76 N/A

Transdeltamethrin0.04 15 87, 78, 93, 107, 78, 86, 97, 111, 86, 97, 71, 75, 95, 

83, 90

89 11

0.5 2 73, 91 82 N/A

Leaf Lettuce

Cis-deltamethrin 0.01 15 95, 83, 92, 94, 102, 85, 87, 94, 101, 86, 90, 87, 89, 

83, 91

91 5.8

0.046 6 90, 92, 55, 83, 87, 89, 83, 91 82 14

Transdeltamethrin0.01 16 110, 85, 90, 82, 75, 83, 90, 93, 111, 96, 98, 96, 96, 

84, 84, 78

91 10

0.046 6 97, 99, 63, 107, 105, 102 95 16

Grass Forage

Cis-deltamethrin 0.01 16 88, 76, 93, 97, 91, 82, 105, 83, 82, 95, 97, 78, 74, 

70, 74, 69

85 11

0.86 3 73, 72, 71 72 1.2

Transdeltamethrin0.01 16 82, 83, 82, 101, 105, 87, 106, 85, 86, 80, 101, 76, 

98, 75, 63, 77

87 12

0.86 3 85, 81, 78 81 3.7
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 8 of 24

Table C.1. Recovery Results from Method Validation of Alfalfa, Lettuce, and Grass Using the Data 

Collection Analytical Method. 

Matrix Spiking 

Level 

(ppm)

No. of 

Samples

Recoveries Obtained (%) Mean 

Recovery 

(%)

Standard 

Deviation 

(%)

Grass Hay

Cis-deltamethrin 0.04 15 75, 97, 97, 106, 85, 88, 95, 75, 80, 80, 80, 81, 81, 

74, 79

85 9.6

0.5 3 91, 97, 127 105 19

Transdeltamethrin0.04 17 70, 116, 102, 109, 84, 94, 96, 81, 80, 91, 82, 81, 94, 

80, 116, 75, 112

92 15

0.5 3 87, 96, 123 102 19

TABLE C.2 Summary of Storage Conditions.

Matrix Storage Temperature

(°C)

Actual Storage Duration*

(Days)

Interval of Demonstrated Storage 

Stability (Days)

Alfalfa forage -2 to -30 60 61

Grass forage 43

Leaf lettuce 31

* Duration from sampling to extraction. Most samples were analyzed the day of, or the day after, extraction. A few 

of the grass samples were analyzed 6 days after extraction.

The individual residue values in samples taken after each of the 10 applications are provided in 

the tables below. The lowest average field trial (LAFT) and the HAFT are also provided.

 
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 9 of 24

Table C.3. Residue Data from Alfalfa Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

*

Residues (ppm)

Cis Trans Total 

Deltamethrin Average LAFT HAFT

Alfalfa Forage: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Alfalfa 

Forage

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4

0.00925 <LOD 0.0112 0.00887 0.0089 0.00455 <LOD 0.00654

<LOD <LOD <0.004 0.0055 0.0055 0.00506 <LOD 0.00705

2

0.00067-

0.00070 0 4

0.00924 <LOD 0.0112 0.0108 0.0108 0.00852 <LOD 0.0105

0.0129 <LOD 0.0148 0.0131 0.0131 0.00931 <LOD 0.0113

3 0.00068 0 4

0.00975 <LOD 0.0117 0.0139 0.0139 0.0140 <LOD 0.0160

0.00637 <LOD 0.0084 0.0131 0.0131 0.0158 <LOD 0.0178

4

0.00066-

0.00068 0 4

0.0171 <LOD 0.0191 0.0200 0.0200 0.0188 <LOD 0.0208

0.0152 <LOD 0.0171 0.0173 0.0173 0.0156 <LOD 0.0175

5

0.00067-

0.00068 0 4

0.0171 <LOD 0.0191 0.0206 0.0206 0.0200 <LOD 0.0220

0.0224 <LOD 0.0244 0.0202 0.0202 0.0140 <LOD 0.0160

6

0.00067-

0.00069 0 4

0.0138 <LOD 0.0158 0.0136 0.0136 0.00927 <LOD 0.0113

0.0200 <LOD 0.0220 0.0209 0.0209 0.0178 <LOD 0.0198

7 0.00066 0 4

0.0353 <LOD 0.0373 0.0388 0.0388 0.062 <LOD 0.0382

0.0217 <LOD 0.0261 0.0249 0.0249 0.0217 <LOD 0.0237

8

0.00066-

0.00068 0 4

0.0274 <LOD 0.0294 0.0281 0.0281 0.0248 <LOD 0.0268

0.0169 <LOD 0.0189 0.0115 0.0115 <LOD <LOD <LOD

9

0.00067-

0.00069 0 4

0.0304 <LOD 0.0324 0.0434 0.0434 0.0496 <LOD 0.0544

0.0154 <LOD 0.0174 0.0170 0.0170 0.0145 <LOD 0.0165

10 0.00067-

0.00068 0 4

0.0299 <LOD 0.0319 0.0380 0.0380 0.0421 <LOD 0.0441

0.0124 <LOD 0.0144 0.0162 0.0162 0.0159 <LOD 0.0179
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 10 of 24

Table C.3. Residue Data from Alfalfa Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

*

Residues (ppm)

Cis Trans Total 

Deltamethrin Average LAFT HAFT

Alfalfa Forage: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Alfalfa 

Forage

Cis and 

TransDeltamethrin

1 0.0013 0 4

0.00555 <LOD 0.00754 0.00693 0.00693 0.00433 <LOD 0.00631

<LOD <LOD <0.004 <0.004 <0.004 <LOD <LOD <0.004

2

0.0013-

0.0014 0 4

0.00651 <LOD 0.00851 0.00752 0.00752 0.00455 <LOD 0.00653

0.0312 <LOD 0.0332 0.0363 0.0363 0.0374 <LOD 0.0394

3

0.0013-

0.0014 0 4

0.00935 <LOD 0.0113 0.00925 0.00925 0.00520 <LOD 0.00719

0.0317 <LOD 0.0337 0.0294 0.0294 0.0231 <LOD 0.0251

4 0.0013 0 4

0.0136 <LOD 0.0156 0.0147 0.0147 0.0119 <LOD 0.0138

0.0314 <LOD 0.0334 0.0360 0.0360 0.0365 <LOD 0.0385

5 0.0013 0 4

0.0165 <LOD 0.0185 0.0164 0.0164 0.0123 <LOD 0.0143

0.0487 <LOD 0.0507 0.0455 0.0455 0.0383 <LOD 0.0403

6 0.0013 0 4

0.0105 <LOD 0.0125 0.0124 0.0124 0.0102 <LOD 0.0122

0.0505 <LOD 0.0525 0.0463 0.0463 0.0380 <LOD 0.0400

7 0.0013 0 4

0.0137 <LOD 0.0157 0.0143 0.0143 0.0108 <LOD 0.0128

0.0265 <LOD 0.0285 0.0324 0.0324 0.0320 <LOD 0.0362

8 0.0013 0 4

0.0354 <LOD 0.0374 0.0409 0.0409 0.0386 0.00582 0.0444

0.0185 <LOD 0.0205 0.0290 0.0290 0.0312 0.00619 0.0374

9 0.0013 0 4

0.0676 <LOD 0.0696 0.0620 0.0620 0.0523 <LOD 0.0543

0.0304 0.00932 0.0478 0.0397 0.0397 0.0496 0.0608 0.0315

10 0.0013 0 4

0.0630 0.00607 0.0690 0.0671 0.0671 0.0590 0.00618 0.0652

0.0299 0.00 0.0298 0.0301 0.0301 0.0421 <LOD 0.0303
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 11 of 24

Table C.3. Residue Data from Alfalfa Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

*

Residues (ppm)

Cis Trans Total 

Deltamethrin Average LAFT HAFT

Alfalfa Hay: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Alfalfa 

Hay

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4

0.0380 <LOD 0.0453 0.0480 0.0480 0.0434 <LOD 0.0507

<LOD <LOD <0.015 <0.015 0.015 <LOD <LOD <0.015

2

0.00067-

0.00070 0 4

0.0281 <LOD 0.0354 0.0399 0.0399 0.0370 <LOD 0.0443

0.0812 <LOD 0.0885 0.0707 0.0707 0.0457 <LOD 0.0529

3 0.00068 0 4

0.0265 <LOD 0.0338 0.0365 0.0365 0.0318 <LOD 0.0391

0.0422 <LOD 0.0495 0.0456 0.0456 0.0345 <LOD 0.0417

4

0.00066-

0.00068 0 4

0.0511 <LOD 0.0583 0.0548 0.0548 0.0439 <LOD 0.0512

0.148 <LOD 0.164 0.153 0.153 0.128 <LOD 0.141

5

0.00067-

0.00068 0 4

0.0485 <LOD 0.0558 0.0589 0.0589 0.0546 <LOD 0.0619

0.0754 0.0176 0.0930 0.0805 0.0805 0.0556 <LOD 0.0680

6

0.00067-

0.00069 0 4

0.0464 <LOD 0.0537 0.0522 0.0522 0.0434 <LOD 0.0507

<LOD <LOD <0.015 0.0278 0.0278 0.0284 <LOD 0.0405

7 0.00066 0 4

0.0621 <LOD 0.0694 0.0716 0.0716 0.0665 <LOD 0.0737

0.0258 <LOD 0.0331 0.0380 0.0380 0.0355 <LOD 0.0428

8

0.00066-

0.00068 0 4

0.0468 <LOD 0.0540 0.0624 0.0624 0.0635 <LOD 0.0707

0.0277 <LOD 0.0350 0.0357 0.0357 0.0290 <LOD 0.0363

9

0.00067-

0.00069 0 4

0.0575 <LOD 0.0648 0.0679 0.0679 0.0636 <LOD 0.0709

<LOD <LOD <0.015 0.015 0.015 <LOD <LOD <0.015

10 0.00067-

0.00068 0 4

0.0781 <LOD 0.0854 0.0848 0.0848 0.0769 <LOD 0.0842

0.0457 <LOD 0.0529 0.0618 0.0618 0.0634 <LOD 0.0707
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 12 of 24

Table C.3. Residue Data from Alfalfa Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

*

Residues (ppm)

Cis Trans Total 

Deltamethrin Average LAFT HAFT

Alfalfa Hay: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Alfalfa 

Hay

Cis and 

TransDeltamethrin

1 0.0013 0 4

0.0180 <LOD 0.0253 0.0213 0.0213 0.00991 <LOD 0.0172

<LOD <LOD 0.015 0.015 0.015 <LOD <LOD 0.015

2

0.0013-

0.0014 0 4

0.0118 <LOD 0.0190 0.0193 0.0193 0.0122 <LOD 0.0195

0.0275 <LOD 0.0348 0.0592 0.0592 0.0763 <LOD 0.0836

3

0.0013-

0.0014 0 4

0.0128 <LOD 0.0201 0.0205 0.0205 0.0136 <LOD 0.0209

0.0614 <LOD 0.0687 0.0643 0.0643 0.0526 <LOD 0.0599

4 0.0013 0 4

0.0230 <LOD 0.0303 0.0326 0.0326 0.0276 <LOD 0.0349

0.0880 <LOD 0.0952 0.0935 0.0935 0.0845 <LOD 0.0918

5 0.0013 0 4

0.0288 <LOD 0.0361 0.0348 0.0348 0.0262 <LOD 0.0335

0.0806 <LOD 0.0878 0.0736 0.0736 0.0520 <LOD 0.0593

6 0.0013 0 4

0.0176 <LOD 0.0249 0.0217 0.0217 0.0111 <LOD 0.0184

0.110 <LOD 0.118 0.141 0.141 0.148 <LOD 0.164

7 0.0013 0 4

0.0332 <LOD 0.0405 0.0391 0.0391 0.0303 <LOD 0.0376

0.0358 <LOD 0.0430 0.0680 0.0680 0.0754 0.0176 0.0930

8 0.0013 0 4

0.0759 <LOD 0.0832 0.0805 0.0805 0.0704 <LOD 0.0777

0.0520 0.0169 0.0689 0.0352 0.0352 <LOD <LOD <0.015

9 0.0013 0 4

0.113 <LOD 0.121 0.1101 0.1101 0.0919 <LOD 0.0992

0.0451 <LOD 0.0524 0.0428 0.0428 0.0258 <LOD 0.0331

10 0.0013 0 4

0.104 <LOD 0.111 0.111 0.111 0.103 <LOD 0.110

0.0302 <LOD 0.0375 0.0363 0.0363 0.0277 <LOD 0.0350
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 13 of 24

Table C.3. Residue Data from Leaf Lettuce Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

*

Residues (ppm)

Cis Trans Total 

Deltamethrin Average LAFT HAFT

Leaf Lettuce: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Lettuce 

Leaves

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4

0.0210 <LOD 0.0227 0.0234 0.0234 0.0224 <LOD 0.0241

<LOD <LOD 0.0035 0.0035 0.0035 <LOD <LOD 0.0035

2

0.00067-

0.00070 0 4

0.0143 <LOD 0.0160 0.0236 0.0236 0.0294 <LOD 0.0311

0.0224 <LOD 0.0241 0.0208 0.0208 0.0158 <LOD 0.0175

3 0.00068 0 4

0.0342 <LOD 0.0360 0.0384 0.0384 0.0391 <LOD 0.0408

0.00942 <LOD 0.0111 0.0128 0.0128 0.0128 <LOD 0.0145

4

0.00066-

0.00068 0 4

0.0358 <LOD 0.0375 0.0372 0.0372 0.0351 <LOD 0.0368

0.0164 <LOD 0.0181 0.0165 0.0165 0.0131 <LOD 0.0148

5

0.00067-

0.00068 0 4

0.0279 <LOD 0.0297 0.0210 0.0210 0.0105 <LOD 0.0122

0.00978 <LOD 0.0115 0.0225 0.0225 0.0113 <LOD 0.0130

6

0.00067-

0.00069 0 4

0.0286 <LOD 0.0303 0.0284 0.0284 0.0248 <LOD 0.0265

0.00533 <LOD 0.00704 0.00797 0.00797 0.00718 <LOD 0.00889

7 0.00066 0 4

0.0310 <LOD 0.0327 0.0290 0.0290 0.0235 <LOD 0.0252

0.00486 <LOD 0.00658 0.00648 0.00648 0.00466 <LOD 0.00638

8

0.00066-

0.00068 0 4

0.0289 <LOD 0.0306 0.0278 0.0278 0.0232 <LOD 0.0249

0.00386 <LOD 0.00588 0.0062 0.0062 0.00481 <LOD 0.00653

9

0.00067-

0.00069 0 4

0.0330 <LOD 0.0348 0.0349 0.0349 0.0332 <LOD 0.0349

0.00298 <LOD 0.00470 0.0045 0.0450 0.00259 <LOD 0.00430

10 0.00067-

0.00068 0 4

0.0387 <LOD 0.0404 0.0425 0.0425 0.0429 <LOD 0.0446

0.00449 <LOD 0.00620 0.0080 0.00795 0.00798 <LOD 0.00970
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 14 of 24

Table C.3. Residue Data from Leaf Lettuce Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

*

Residues (ppm)

Cis Trans Total 

Deltamethrin Average LAFT HAFT

Leaf Lettuce: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Lettuce 

Leaves

Cis and 

TransDeltamethrin

1 0.0013 0 4

0.0112 <LOD 0.0129 0.0140 0.0140 0.0133 <LOD 0.0150

0.00284 <LOD 0.00456 0.00507 0.00507 0.00385 <LOD 0.00557

2

0.0013-

0.0014 0 4

0.00880 <LOD 0.0105 0.0101 0.0101 0.00800 <LOD 0.00972

0.0133 <LOD 0.0150 0.0192 0.0192 0.0217 <LOD 0.0234

3

0.0013-

0.0014 0 4

0.00989 <LOD 0.0116 0.0106 0.0106 0.00796 <LOD 0.00968

0.00798 <LOD 0.00970 0.0102 0.0102 0.00891 <LOD 0.0106

4 0.0013 0 4

0.00958 <LOD 0.0113 0.0120 0.0120 0.0109 <LOD 0.0126

0.0131 <LOD 0.0148 0.0168 0.0168 0.0170 <LOD 0.0187

5 0.0013 0 4

0.0106 <LOD 0.0123 0.0122 0.0122 0.0103 <LOD 0.0120

0.0171 <LOD 0.0188 0.0153 0.0153 0.00995 <LOD 0.0117

6 0.0013 0 4

0.00528 <LOD 0.00700 0.00645 0.00645 0.00419 <LOD 0.00590

0.00716 <LOD 0.00888 0.00872 0.00872 0.00684 <LOD 0.00855

7 0.0013 0 4

0.00429 <LOD 0.00601 0.00851 0.00851 0.00930 <LOD 0.0110

0.0317 <LOD 0.0335 0.0342 0.0342 0.0331 <LOD 0.0348

8 0.0013 0 4

0.0205 <LOD 0.0222 0.0202 0.0202 0.0164 <LOD 0.0181

0.00403 <LOD 0.00575 0.00614 0.00614 0.00481 <LOD 0.00652

9 0.0013 0 4

0.0395 <LOD 0.0412 0.0365 0.0365 0.0301 <LOD 0.0318

0.00324 <LOD 0.00496 0.00566 0.00566 0.00464 <LOD 0.00635

10 0.0013 0 4

0.0357 <LOD 0.0375 0.0331 0.0331 0.0269 <LOD 0.0286

0.00374 <LOD 0.00545 0.00632 0.00632 0.00547 <LOD 0.00719
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 15 of 24

Table C.3. Residue Data from Grass Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

*

Residues (ppm)

Cis Trans Total 

Deltamethrin Average LAFT HAFT

Grass Forage: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Grass 

Forage

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4

0.00910 <LOD 0.0109 0.0149 0.0149 0.0170 <LOD 0.0188

0.00360 <LOD 0.00538 0.00525 0.00525 0.00334 <LOD 0.00512

2

0.00067-

0.00070 0 4

0.0214 <LOD 0.0232 0.0197 0.0197 0.0144 <LOD 0.0162

0.00726 <LOD 0.00904 0.0117 0.0117 0.0125 <LOD 0.0143

3 0.00068 0 4

0.0236 <LOD 0.0254 0.0292 0.0292 0.0289 0.00404 0.0330

0.0218 <LOD 0.0236 0.0216 0.0216 0.0177 <LOD 0.0195

4

0.00066-

0.00068 0 4

0.0185 <LOD 0.0203 0.0188 0.0188 0.0154 <LOD 0.0172

0.0161 <LOD 0.0179 0.0174 0.0174 0.0150 <LOD 0.0168

5

0.00067-

0.00068 0 4

0.0172 <LOD 0.0190 0.0189 0.0189 0.0170 <LOD 0.0188

0.0154 <LOD 0.0172 0.0169 0.0169 0.0147 <LOD 0.0165

6

0.00067-

0.00069 0 4

0.0112 <LOD 0.0130 0.0153 0.0153 0.0157 <LOD 0.0175

0.0278 0.00542 0.0333 0.0297 0.0297 0.0215 0.00461 0.0261

7 0.00066 0 4

0.0185 <LOD 0.0202 0.0223 0.0223 0.0225 <LOD 0.0243

0.0221 0.00599 0.0281 0.0316 0.0316 0.0289 0.00625 0.0351

8

0.00066-

0.00068 0 4

0.0241 0.00411 0.0282 0.0295 0.0295 0.0262 0.00464 0.0308

0.0281 0.00572 0.00338 0.0324 0.0324 0.0238 0.00729 0.00310

9

0.00067-

0.00069 0 4

0.0290 <LOD 0.0308 0.0285 0.0285 0.0243 <LOD 0.0261

0.0163 0.00546 0.0218 0.0261 0.0261 0.0244 0.00600 0.0304

10 0.00067-

0.00068 0 4

0.0376 0.00526 0.0429 0.0339 0.0339 0.0231 <LOD 0.0249

0.0187 0.00664 0.0254 0.0303 0.0303 0.0277 0.00754 0.0352
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 16 of 24

Table C.3. Residue Data from Grass Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

*

Residues (ppm)

Cis Trans Total 

Deltamethrin Average LAFT HAFT

Grass Forage: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Grass

Forage

Cis and 

TransDeltamethrin

1 0.0013 0 4

0.0148 <LOD 0.0166 0.0135 0.0135 0.00861 <LOD 0.0104

0.00622 <LOD 0.00800 0.00758 0.00758 0.00538 <LOD 0.00716

2

0.0013-

0.0014 0 4

0.0157 <LOD 0.0175 0.0157 0.0157 0.0120 <LOD 0.0138

0.00971 <LOD 0.0115 0.0114 0.0114 0.00949 <LOD 0.0113

3

0.0013-

0.0014 0 4

0.0260 <LOD 0.0278 0.0259 0.0259 0.0221 <LOD 0.0239

0.0176 <LOD 0.0194 0.0202 0.0202 0.0192 <LOD 0.0210

4 0.0013 0 4

0.0150 <LOD 0.0168 0.0190 0.0190 0.0195 <LOD 0.0212

0.0233 <LOD 0.0250 0.0245 0.0245 0.0222 <LOD 0.0240

5 0.0013 0 4

0.0192 <LOD 0.0210 0.0192 0.0192 0.0157 <LOD 0.0174

0.0266 <LOD 0.0284 0.0257 0.0257 0.0211 <LOD 0.0229

6 0.0013 0 4

0.00955 <LOD 0.0113 0.0146 0.0146 0.0161 <LOD 0.0179

0.0158 <LOD 0.0176 0.0248 0.0248 0.0267 0.00529 0.0320

7 0.0013 0 4

0.0317 <LOD 0.0335 0.0342 0.0342 0.0331 <LOD 0.0348

0.0275 0.00576 0.0332 0.0274 0.0274 0.0177 0.00377 0.0215

8 0.0013 0 4

0.0323 <LOD 0.0341 0.0317 0.0317 0.0275 <LOD 0.0292

0.0249 0.00429 0.0292 0.0305 0.0305 0.0267 0.00505 0.0317

9 0.0013 0 4

0.0773 <LOD 0.0791 0.0748 0.0748 0.0687 <LOD 0.0704

0.0202 0.00554 0.0257 0.0222 0.0222 0.0151 0.00359 0.0187

10 0.0013 0 4

0.0852 <LOD 0.0870 0.0698 0.0698 0.0483 0.0424 0.0525

0.0173 0.00437 0.0217 0.0252 0.0252 0.0211 0.00755 0.0287
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 17 of 24

Table C.3. Residue Data from Grass Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

*

Residues (ppm)

Cis Trans Total 

Deltamethrin Average LAFT HAFT

Grass Hay: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Grass 

Hay

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4

0.0823 <LOD 0.0920 0.0867 0.0867 0.0717 <LOD 0.0814

<LOD <LOD <0.02 0.02 0.02 <LOD <LOD <0.02

2

0.00067-

0.00070 0 4

0.0675 <LOD 0.0772 0.0772 0.0772 0.0674 <LOD 0.0771

0.0189 <LOD 0.0285 0.0319 0.0319 0.0256 <LOD 0.0352

3 0.00068 0 4

0.0662 <LOD 0.0759 0.0809 0.0809 0.0763 <LOD 0.0859

0.0338 <LOD 0.0435 0.0411 0.0411 0.0290 <LOD 0.0387

4

0.00066-

0.00068 0 4

0.0617 <LOD 0.0713 0.0795 0.0795 0.0779 <LOD 0.0876

0.0429 <LOD 0.0525 0.0521 0.0521 0.0420 <LOD 0.0516

5

0.00067-

0.00068 0 4

0.110 <LOD 0.120 0.122 0.122 0.114 <LOD 0.124

0.0332 <LOD 0.0429 0.0461 0.0461 0.0395 <LOD 0.0492

6

0.00067-

0.00069 0 4

0.0877 <LOD 0.0974 0.0955 0.0955 0.0839 <LOD 0.0936

0.0437 <LOD 0.0534 0.0573 0.0573 0.0514 <LOD 0.0611

7 0.00066 0 4

0.139 0.0194 0.158 0.137 0.137 0.106 <LOD 0.116

0.0478 <LOD 0.0575 0.0574 0.0574 0.0475 <LOD 0.0572

8

0.00066-

0.00068 0 4

0.114 0.0200 0.134 0.133 0.133 0.109 0.0219 0.131

0.0415 <LOD 0.0512 0.0501 0.0501 0.0393 <LOD 0.0490

9

0.00067-

0.00069 0 4

0.140 0.0224 0.162 0.162 0.162 0.141 0.0209 0.162

0.0413 <LOD 0.0510 0.0550 0.0550 0.0492 <LOD 0.0589

10 0.00067-

0.00068 0 4

0.155 0.0236 0.178 0.188 0.188 0.171 0.0266 0.197

0.0396 <LOD 0.0493 0.0491 0.0491 0.0392 <LOD 0.0489
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 18 of 24

Table C.3. Residue Data from Grass Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

*

Residues (ppm)

Cis Trans Total 

Deltamethrin Average LAFT HAFT

Grass Hay: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Grass 

Hay

Cis and 

TransDeltamethrin

1 0.0013 0 4

0.0225 <LOD 0.0322 0.0421 0.0421 0.0423 <LOD 0.0520

0.0203 <LOD 0.0300 0.0298 0.0298 0.0198 <LOD 0.0295

2

0.0013-

0.0014 0 4

0.0461 <LOD 0.0558 0.0555 0.0555 0.0456 <LOD 0.0552

0.0193 <LOD 0.0290 0.0324 0.0324 0.0261 <LOD 0.0358

3

0.0013-

0.0014 0 4

0.0625 <LOD 0.0722 0.0712 0.0712 0.0605 <LOD 0.0702

0.0726 <LOD 0.0823 0.0823 0.0823 0.0726 <LOD 0.0823

4 0.0013 0 4

0.118 <LOD 0.128 0.121 0.121 0.103 <LOD 0.113

0.0581 0.0332 0.0913 0.0987 0.0987 0.0775 0.0283 0.106

5 0.0013 0 4

0.0696 <LOD 0.0792 0.0791 0.0791 0.0693 <LOD 0.0790

0.0754 0.0366 0.112 0.123 0.123 0.0821 0.0514 0.133

6 0.0013 0 4

0.0603 <LOD 0.0700 0.0729 0.0729 0.0661 <LOD 0.0758

0.0792 0.0819 0.161 0.152 0.152 0.0788 0.0633 0.142

7 0.0013 0 4

0.156 <LOD 0.166 0.154 0.154 0.131 <LOD 0.141

0.0601 0.0478 0.108 0.104 0.104 0.0553 0.0439 0.0992

8 0.0013 0 4

0.130 <LOD 0.140 0.140 0.140 0.130 <LOD 0.140

0.0654 0.0744 0.140 0.128 0.128 0.0666 0.0489 0.116

9 0.0013 0 4

0.322 <LOD 0.332 0.355 0.355 0.349 0.0275 0.377

0.0556 0.0593 0.115 0.118 0.118 0.0415 0.0794 0.121

10 0.0013 0 4

0.275 0.0494 0.324 0.347 0.347 0.331 0.0375 0.369

0.0415 0.108 0.150 0.150 0.150 0.0502 0.0993 0.150
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 19 of 24

Table 5.3.1. Summary of Total Residues from Alfalfa Forage Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

Residues (ppm)

Min Max LAFT HAFT Mean SD

Alfalfa Forage: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Alfalfa 

Forage

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4 <0.004 0.0112 0.0055 0.0089 0.0073 0.00302

2

0.00067-

0.00070 0 4 0.0105 0.0148 0.0108 0.0131 0.0120 0.0020

3 0.00068 0 4 0.0084 0.0178 0.0131 0.0139 0.0135 0.00423

4

0.00066-

0.00068 0 4 0.0172 0.0208 0.0173 0.0200 0.0187 0.00144

5

0.00067-

0.00068 0 4 0.0160 0.0244 0.0202 0.0206 0.0204 0.00363

6

0.00067-

0.00069 0 4 0.0113 0.0220 0.0136 0.0209 0.0172 0.00471

7 0.00066 0 4 0.0237 0.0382 0.0249 0.0388 0.0313 0.00749

8

0.00066-

0.00068 0 4 <0.004 0.0294 0.0115 0.0281 0.0198 0.01142

9

0.00067-

0.00069 0 4 0.0165 0.0544 0.0170 0.0434 0.0302 0.0178

10 0.00067-

0.00068 0 4 0.0144 0.0441 0.0162 0.0380 0.0271 0.0136

Alfalfa Forage: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Alfalfa 

Forage

Cis and 

TransDeltamethrin

1 0.0013 0 4 <0.004 0.0075 <0.004 0.0069 0.0055 0.0018

2

0.0013-

0.0014 0 4 0.0066 0.0394 0.0075 0.0363 0.0219 0.0168

3

0.0013-

0.0014 0 4 0.0072 0.0337 0.0093 0.0294 0.0194 0.0122

4 0.0013 0 4 0.0139 0.0385 0.0147 0.0360 0.0254 0.0124

5 0.0013 0 4 0.0143 0.0507 0.0164 0.0455 0.0310 0.0174

6 0.0013 0 4 0.0122 0.0525 0.0124 0.0463 0.0293 0.0202

7 0.0013 0 4 0.0128 0.0362 0.0143 0.0324 0.0228 0.0101

8 0.0013 0 4 0.0205 0.0444 0.0290 0.0409 0.0349 0.0102

9 0.0013 0 4 0.0315 0.0696 0.0397 0.0620 0.0508 0.0158

10 0.0013 0 4 0.0040 0.0690 0.0301 0.0671 0.0343 0.0332

LAFT = Lowest Average Field Trial, HAFT = Highest Average Field Trial, SD = Standard Deviation. For computation of the 

LAFT, HAFT, median, mean, and standard deviation, values <LOQ are assumed to be at the LOQ.
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 20 of 24

Table 5.3.1. Summary of Total Residues from Alfalfa Hay Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

Residues (ppm)

Min Max LAFT HAFT Mean SD

Alfalfa Hay: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Alfalfa 

Hay

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4 <0.0150 0.0507 0.0150 0.0480 0.0316 0.0193

2

0.00067-

0.00070 0 4 0.0356 0.0885 0.0399 0.0707 0.0555 0.0233

3 0.00068 0 4 0.0340 0.0495 0.0365 0.0456 0.0413 0.0065

4

0.00066-

0.00068 0 4 0.0512 0.164 0.0548 0.1530 0.0564 0.0069

5

0.00067-

0.00068 0 4 0.0560 0.0930 0.0589 0.0805 0.0603 0.0029

6

0.00067-

0.00069 0 4 <0.015 0.0537 0.0278 0.0522 0.0400 0.0176

7 0.00066 0 4 0.0331 0.0737 0.0380 0.0716 0.0613 0.0125

8

0.00066-

0.00068 0 4 0.0350 0.0707 0.0357 0.0624 0.0480 0.0205

9

0.00067-

0.00069 0 4 <0.015 0.0709 0.015 0.0679 0.0565 0.0140

10 0.00067-

0.00068 0 4 0.0529 0.0854 0.0618 0.0848 0.0681 0.0195

Alfalfa Hay: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Alfalfa 

Hay

Cis and 

TransDeltamethrin

1 0.0013 0 4 <0.015 0.0253 0.0150 0.0213 0.0182 0.0049

2

0.0013-

0.0014 0 4 0.0354 0.0836 0.0193 0.0592 0.0393 0.0305

3

0.0013-

0.0014 0 4 0.0201 0.0687 0.0205 0.0643 0.0424 0.0255

4 0.0013 0 4 0.0305 0.0952 0.0326 0.0935 0.0631 0.0352

5 0.0013 0 4 0.0337 0.0878 0.0348 0.0736 0.0515 0.0193

6 0.0013 0 4 0.0186 0.164 0.0217 0.1410 0.0792 0.0680

7 0.0013 0 4 0.0378 0.0930 0.0391 0.0680 0.0537 0.0263

8 0.0013 0 4 0.0150 0.0832 0.0352 0.0805 0.0579 0.0314

9 0.0013 0 4 0.0333 0.1205 0.0428 0.1101 0.0765 0.0404

10 0.0013 0 4 0.0178 0.1110 0.0363 0.1110 0.0272 0.0108

LAFT = Lowest Average Field Trial, HAFT = Highest Average Field Trial, SD = Standard Deviation. For computation of the 

LAFT, HAFT, median, mean, and standard deviation, values <LOQ are assumed to be at the LOQ.
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 21 of 24

Table 5.3.1. Summary of Total Residues from Lettuce Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) N

Residues (ppm)

Min Max LAFT HAFT Mean SD

Leaf Lettuce: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Lettuce 

Leaves

Cis and 

TransDeltamethrin

1

0.00066-

0.00067 0 4 <0.0035 0.0241 0.0035 0.0234 0.0139 0.0114

2

0.00067-

0.00068 0 4 0.0163 0.0311 0.0208 0.0236 0.0225 0.0069

3

0.00067-

0.00068 0 4 0.0114 0.0408 0.0128 0.0384 0.0259 0.0150

4

0.00067-

0.00068 0 4 0.0151 0.0375 0.0165 0.0372 0.0271 0.0120

5

0.00073-

0.00066 0 4 0.0115 0.0297 0.0210 0.0225 0.0169 0.0087

6

0.00067-

0.00068 0 4 0.0073 0.0303 0.0080 0.0284 0.0185 0.0119

7 0.00067 0 4 0.0064 0.0327 0.0065 0.0290 0.0180 0.0133

8

0.00066-

0.00067 0 4 0.0059 0.0306 0.0062 0.0278 0.0172 0.0127

9

0.00067-

0.00068 0 4 0.0043 0.0349 0.0045 0.0349 0.0200 0.0175

10 0.00067-

0.00068 0 4 0.0065 0.0446 0.0080 0.0425 0.0255 0.0201

Leaf Lettuce: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Lettuce 

Leaves

Cis and 

TransDeltamethrin

1 0.0013 0 4 0.0048 0.0150 0.0051 0.0140 0.0098 0.0052

2 0.0013 0 4 0.0100 0.0234 0.0101 0.0192 0.0150 0.0063

3 0.0013 0 4 0.0100 0.0116 0.0102 0.0106 0.0107 0.0009

4 0.0013 0 4 0.0116 0.0187 0.0120 0.0168 0.0147 0.0032

5 0.0013 0 4 0.0120 0.0188 0.0122 0.0153 0.0140 0.0034

6 0.0013 0 4 0.0062 0.0089 0.0065 0.0087 0.0079 0.0014

7 0.0013 0 4 0.0060 0.0348 0.0085 0.0342 0.0213 0.0150

8 0.0013 0 4 0.0060 0.0222 0.0061 0.0202 0.0134 0.0083

9 0.0013 0 4 0.0052 0.0412 0.0057 0.0365 0.0214 0.0183

10 0.0013 0 4 0.0057 0.0375 0.0063 0.0331 0.0200 0.0158

LAFT = Lowest Average Field Trial, HAFT = Highest Average Field Trial, SD = Standard Deviation. For computation of the 

LAFT, HAFT, median, mean, and standard deviation, values <LOQ are assumed to be at the LOQ.
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 22 of 24

Table 5.3.1. Summary of Total Residues from Grass Forage Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

Residues (ppm)

Min Max LAFT HAFT Mean SD

Grass Forage: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Grass 

Forage

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4 0.0053 0.0188 0.0053 0.0149 0.0103 0.0064

2

0.00067-

0.00070 0 4 0.0093 0.0232 0.0117 0.0197 0.0159 0.0058

3

0.00067-

0.00068 0 4 0.0197 0.0330 0.0216 0.0292 0.0255 0.0055

4

0.00067-

0.00068 0 4 0.0170 0.0203 0.0174 0.0188 0.0183 0.0014

5

0.00066-

0.00067 0 4 0.0167 0.0190 0.0169 0.0189 0.0181 0.0012

6

0.00067-

0.00069 0 4 0.0132 0.0333 0.0153 0.0297 0.0226 0.0089

7 0.00066 0 4 0.0205 0.0351 0.0223 0.0316 0.0271 0.0062

8

0.00073-

0.00067 0 4 0.0282 0.0338 0.0295 0.0324 0.0310 0.0023

9

0.00066-

0.00068 0 4 0.0218 0.0308 0.0261 0.0285 0.0274 0.0043

10 0.00067 0 4 0.0251 0.0429 0.0303 0.0339 0.0321 0.0086

Grass Forage: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Grass 

Forage

Cis and 

TransDeltamethrin

1 0.0013 0 4 0.00716 0.0166 0.0076 0.0135 0.0108 0.0043

2

0.0013-

0.0014 0 4 0.0113 0.0175 0.0114 0.0157 0.0137 0.0029

3 0.0013 0 4 0.0194 0.0278 0.0202 0.0259 0.0232 0.0037

4 0.0013 0 4 0.0168 0.0250 0.0190 0.0245 0.0220 0.0037

5

0.0014-

0.0013 0 4 0.0174 0.0284 0.0192 0.0257 0.0227 0.0046

6 0.0013 0 4 0.0113 0.0320 0.0146 0.0248 0.0199 0.0086

7 0.0013 0 4 0.0215 0.0348 0.0274 0.0342 0.0309 0.0063

8 0.0013 0 4 0.0292 0.0341 0.0305 0.0317 0.0302 0.0038

9 0.0013 0 4 0.0187 0.0791 0.0222 0.0748 0.0486 0.0308

10 0.0013 0 4 0.0217 0.0870 0.0252 0.0698 0.0470 0.0295

LAFT = Lowest Average Field Trial, HAFT = Highest Average Field Trial, SD = Standard Deviation. For computation of the 

LAFT, HAFT, median, mean, and standard deviation, values <LOQ are assumed to be at the LOQ.
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 23 of 24

Table 5.3.1. Summary of Total Residues from Grass Hay Field Trials with Deltamethrin

Crop 

Matrix Analyte

No. of 

Applications

Applic. 

Rate

(lb 

ai/acre)

PHI 

(days) n

Residues (ppm)

Min Max LAFT HAFT Mean SD

Grass Hay: Proposed Total Application Rate = 0.0067 lb ai/A (1⁄2 x)

Grass 

Hay

Cis and 

TransDeltamethrin

1

0.00066-

0.00068 0 4 <0.0200 0.0920 <0.02 0.0867 0.0535 0.0389

2

0.00067-

0.00070 0 4 0.0289 0.0772 0.0319 0.0772 0.0549 0.0262

3

0.00067-

0.00068 0 4 0.0390 0.0859 0.0411 0.0809 0.0613 0.0235

4

0.00067-

0.00068 0 4 0.0520 0.0876 0.0521 0.0795 0.0661 0.0171

5

0.00066-

0.00067 0 4 0.0432 0.1240 0.0461 0.122 0.0842 0.0438

6

0.00067-

0.00069 0 4 0.0537 0.0974 0.0573 0.0955 0.0767 0.0224

7 0.00066 0 4 0.0572 0.1584 0.0574 0.137 0.0974 0.0491

8

0.00073-

0.00067 0 4 0.0493 0.1340 0.0501 0.133 0.0914 0.0474

9

0.00066-

0.00068 0 4 0.0513 0.1624 0.0550 0.162 0.1087 0.0618

10 0.00067 0 4 0.0489 0.1976 0.0491 0.188 0.1188 0.0805

Grass Hay: Proposed Total Application Rate = 0.0134 lb ai/A (1x)

Grass 

Hay

Cis and 

TransDeltamethrin

1 0.0013 0 4 0.0295 0.0520 0.0298 0.0421 0.0362 0.0108

2

0.0013-

0.0014 0 4 0.0293 0.0558 0.0324 0.0555 0.0443 0.0137

3 0.0013 0 4 0.0705 0.0823 0.0712 0.0823 0.0771 0.0065

4 0.0013 0 4 0.0913 0.1280 0.0987 0.121 0.1095 0.0153

5

0.0014-

0.0013 0 4 0.0790 0.1333 0.0791 0.123 0.1011 0.0265

6 0.0013 0 4 0.0703 0.1611 0.0729 0.152 0.1124 0.0460

7 0.0013 0 4 0.0992 0.1078 0.1036 0.154 0.0640 0.0459

8 0.0013 0 4 0.1160 0.1398 0.1277 0.139 0.0753 0.0612

9 0.0013 0 4 0.1150 0.3770 0.1179 0.354 0.0851 0.0388

10 0.0013 0 4 0.1490 0.3690 0.1495 0.347 0.1116 0.0438

LAFT = Lowest Average Field Trial, HAFT = Highest Average Field Trial, SD = Standard Deviation. For computation of the 

LAFT, HAFT, median, mean, and standard deviation, values <LOQ are assumed to be at the LOQ.

D. CONCLUSION

The data that Bayer Environmental Science submitted are adequate to assess the residues of 

deltamethrin that occurred in trials performed on alfalfa forage, alfalfa hay, leaf lettuce, grass 

forage, and grass hay when deltamethrin was applied ten times at application rates of 0.00067

and 0.0013 lb ai/A. Bayer demonstrated that the analytical method is adequate for quantifying 

residues of deltamethrin on the tested commodities. Storage stability data that have been 
Deltamethrin/PC Code 097805/Bayer CropScience

OCSPP 860.1500/OECD IIA 6.3.1, 6.3.2, 6.3.3 and IIIA 8.3.1, 8.3.2, 8.3.3

Crop Field Trials – Alfalfa (Forage and Hay), Grass (Forage and Hay), Leaf Lettuce (Leaves)

_____________________________________________________________________________________________

DP Barcode D423045/MRID #49114112 Page 24 of 24

submitted for deltamethrin in support of previous tolerance petitions are adequate to demonstrate 

that residues were stable in the samples taken in the mosquito adulticide trials. 

E. REFERENCES

None. 

F. DOCUMENT TRACKING

Petition Number: 3F8210

DP Number: D423045 

PC Code: 097805