[Federal Register Volume 65, Number 186 (Monday, September 25, 2000)]
[Notices]
[Page 57611]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 00-24530]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[30DAY-72-00]


Agency Forms Undergoing Paperwork Reduction Act Review

    The Centers for Disease Control and Prevention (CDC) publishes a 
list of information collection requests under review by the Office of 
Management and Budget (OMB) in compliance with the Paperwork Reduction 
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call 
the CDC Reports Clearance Officer at (404) 639-7090. Send written 
comments to CDC, Desk Officer; Human Resources and Housing Branch, New 
Executive Office Building, Room 10235; Washington, DC 20503. Written 
comments should be received within 30 days of this notice.

Proposed Project

    Exposure to Aerosolized Brevetoxins During Red Tide Events--New--
National Center for Environmental Health (NCEH). Gymnodinium breve is 
the marine dinoflagellate responsible for extensive blooms (called red 
tides) that form in the Gulf of Mexico. G. breve produces potent 
toxins, called brevetoxins, that have been responsible for killing 
millions of fish and other marine organisms. The biochemical activity 
of brevetoxins is not completely understood and there is very little 
information regarding human health effects from environmental 
exposures, such as inhaling brevetoxin that has been aerosolized and 
swept onto the coast by offshore winds. The National Center for 
Environmental Health (NCEH), Centers for Disease Control and Prevention 
(CDC) is planning to recruit 100 people who work along the coast of 
Florida and who potentially will be occupationally exposed to 
aerosolized red tide toxins some time during the year following 
recruitment.
    NCEH plans on administering a base line respiratory health 
questionnaire and conducting pre- and post-shift pulmonary function 
tests during a time when there is no red tide reported near the area. 
When a red tide develops, we plan to administer a symptom survey and 
conduct pulmonary function testing (PFT) on a group of study 
participants who are working in the area where the red tide is near 
shore, and on a control group of study participants who are not working 
in an area where the red tide is near shore (i.e., are not exposed to 
the red tide). We will then compare (1) symptom reports before and 
during the red tide and (2) the changes in baseline PFT values during 
the work shift (differences between pre- and post-shift PFT results 
without exposure to red tide) with the changes in PFT values during the 
work shift when individuals are exposed to red tide. In addition, we 
plan to assist in collecting biological specimens (inflammatory cells 
from nose and throat swabs) to assess whether they can be used to 
verify exposure and to demonstrate a biological effect (i.e., 
inflammatory response) from exposure to red tide. There are no costs to 
respondents. The total burden is estimated to be 201 hours.

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                                                                                     Number of    Average burden
                           Respondents                               Number of     responses per   per response
                                                                    respondents     respondent       (in hrs.)
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Pulmonary History Questionnaire.................................             100               1           20/60
Symptom Questionnaire...........................................             100              20            5/60
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    Dated: September 19, 2000.
Nancy Cheal,
Acting Associate Director for Policy, Planning, and Evaluation, Centers 
for Disease Control and Prevention (CDC).
[FR Doc. 00-24530 Filed 9-22-00; 8:45 am]
BILLING CODE 4163-18-P