### UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D .C . 20460



### Kara S. Giddings, Ph.D. Regulatory Affairs Manager Monsanto Company 800 N. Lindbergh Blvd. St. Louis, Missouri 63167 

# FEB 042015 OFFICE OF CHEMICAL SAFETY AND POL LUTION PREVENTION



### Subject: Com Plant Incorporated Protectants with MON 87411 (containing DvSnf7 dsRNA and 

### Bacillus thuringiensis Cry3Bbl Protein and the Genetic Materials (Vector PV - ZMIR 10871) Necessary for their Production in MON 87411 (OECD Unique Identifier MON-87411-9) in combination with 

### Bacillus thuringiensis (Bt) Cry Proteins (CrylA.105, Cry2Ab2, Cry1F, V ip3Aa20, Cry3Bb1,Cry1 Ab and Cry34Ab 1/Cry35Ab I). EPA Experimental Use Permit Number: 524-EUP-1 04 Application Dated: October 10,2014, Amendment December 19,2014 Ef fective Dates: Immediately through February 28, 2017 (includes planting and associated activities e .g. collection offield data, harvesting, processing.) Quantity & 

### Acres Authorized: • 2015: 4597 acres to be planted with 275,820 pounds of seed containing 2.13 x I

# o-2 

### grams DvSnf7 dsRNA; 686.63 grams Cry3Bbl; • 2016:4959 acres to be planted with 279,540 pounds of seed containing 2.3 xi0-2 

### grams DvSnf7 dsRNA and 688.92 g rams Cry3Bbl; • Total: 9556 acres to be planted with 573 ,3 60 pounds of seed containing 4.43 x I

# o- 2 

### grams DvSnf7 dsRNA; 1327.56 grams Cry3Bbl. Dear Dr. Giddings: On the basis ofthe information furnished b y the applicant (and the submitted program) the U.S. Environmental Protection Agency (EPA) hereby amends/extends the subject Experimental Use Permit (EUP) under section 5 ofthe Federal Insecticide, Fungicide, and Rodenticide Act to test Com Plant Incorporated Protectants wit h MON 87411 (containing DvSnf7 dsRNA and 

### Bacillus thuringiensis Cry3Bbl Protein and the genetic materials (vector PV- ZMIR10871) necessary for their production in MON 87411 (OECD Unique Identifier MON- 87411-9) in combination with 

### Bacillus thuringiensis (Bt ) Cry Proteins (Cry IA. I 05, Cry2Ab2, CryIF, Vip3Aa20, Cry3Bb l, Cry34Abi/Cry35Abl and Cry lAb)). The EUP is authorized only in the States ofAlabama (AL), Arkansas (AR), California (CA), Colorado (CO), Florida (FL), Georgia (GA), Hawaii (HI) , Illinois (IL) , Indiana (IN) , Iowa (lA) , Kansas (KS), Louis iana (LA) , Michigan (Ml), Minnesota (MN) , Mississippi (MS), Missouri (MO), Nebraska (NE), North Carolina (NC), North Dakota (ND), Ohio (OH) , Pennsylvania (PA), South Carolina (SC), South Dakota (SD), Tennessee (TN),Texas (TX), Washington (W A) , Wisconsin (WI) and the Commonweal th of Puerto Rico (PR), and allows testing the efficacy of in sect resistance transgenes , evaluation of agronomic performance, and production of sample material for regulatory studies.EPA EU P No. 524-EUP-104 2015 Amendment/Extension Letter Shipme nt and use under this permit are subject to the provisions of 40 CFR Part 172 . The Bt proteins to be used in the single or co mbina t ion traits in the proposed EUP include CrylA.I 05 , Cry2Ab2 , Cry! F , Vip3Aa20 , Cry3Bbl , Cry34Abl/Cry35Abl and Cry JAb. The E PA determined the envi r onmental and human health safety of these proteins and previously exe mp ted them from the r equirement of a tolerance ( 40 CFR 1 7 4.50 I , 1 7 4.502 , 174.506 , 174.511 , 174.518 , 174 . 519 , 174.520 , and 174.528).The EPA has also established a permanent tolerance exemption for nucleic acids , in cluding the dsRNA t hat is part of

the PIPs ( 40 CFR 174.507). Other marker proteins PAT , CP4 EPSPS , and PMI are also exempt from the requ ir ement of a tolerance ( 40 CFR 174.522, I 74.523 , 174.527). H a r vested plant material from breeding stacks that have n ot yet been commercially registered may not be allowed to enter the food or feed

supp l y. Any pesticide treatments (e.g., herbicides) of the plant s under the EUP must have applicable

regi strat i o n s and tolerances/exemptions to allow release of t he treated plant material in to the food/feed supp ly . The Section G review of this EUP is enclosed (US EPA/BPPD review from K. Martin toM. Mendelsohn , 2/2/20 15). · Prior to s hipm e nt and/or use of the subject corn , you mu s t consult with the pesticide regulatory officia l s and, if applicable, the biotechnology regulatory officials of the State(s) 1 in which you will conduct your exper iment a l program, and obtain a State permit or licen se if suc h i s required. Amendment/Extension of

this Federal permit does not negate the need for permission from individua l States. Prior to initiating t hi s experimental program in any State, you are required to notify the lead Agency of the State(s) in which you w i ll conduct your experimental program of the specific testing program (when , whe re , how much, etc.). Failure to do so may result in revocation or modification of this EUP. You must comply with all requirements of the USDA/APHIS as they apply to the pr oposed testing. You must provide notice to the State pesticide regulatory agency at least 72 hours before you use the experimental use product. You must also pro vide a copy of this authorization l etter and stamped label, as well as t he non-confidential portion of the Decemb er 19 , 20 14 Section G Experime ntal Program, to all cooperators , participants and users prior to the initial pesticide use made in accordance with the EUP. The EPA will notify the relevant EPA Region(s ) of the approval of this EUP by sending copies ofthis approval letter to them. Condi tion s under which the EPA is issuing this EUP are as follows. I . Harve sted plant material from breeding stacks that hav e not yet been commercially registered may not be allowed to enter the food or feed supp l y. 2. Prior t o planting, Monsanto must conduct an evaluation of distance between selected sites and federally-l i sted threatened or endangered lepidopteran and coleopteran species and critical habitat for such spec ies. Species and critical habitat that are proposed for federal listing will be included

in t hi s eva luation . S pecies location information will be obtained from the HFRA Endangered Species T ask Force (FESTF) Information Management Syste m (IMS) (at the county-level) or from the FESTF Multi- Juri sdictio nal Database (also known as "NatureServe location data") (at

the sub-county level). Monsanto must not plant experimental trials within 1320 **feet(~** mile) of reported l ocations o f such spec ie s (excluding extirpated or historic locations) or critical habitat. 3. Th e total acreage and amount of PIP corn seed to be used shall not exceed the quantity authorized by this EUP and li sted in Attachment I - Authorized P I Ps , Amounts and Acreage. 1 For the purpose of this letter and final report, the terms "State(s)" and "State-by-State" include the Commonwealth of Puerto Rico . Page 2 ofll

## EPA EUP No. 

## 524-EUP-1 04 20 15 Amendment/Extension Letter We note that the approach to acreage calculation is different from previous submissions. Traditionally, EPA has required Monsanto to specify the number of PIP, non-PIP, and border acres for each event combination under investigation along with the total amount ofprotein for each protein ofthe combination. In addition, you were required to specify the states (including the Commonwealth of Puerto Rico) where the EUP planting would take place. To allow more flexibility in**pl~nning** 

### and implementing the investigation ofMON 87411, while still meeting regulatory requirements, Monsanto has proposed acreage listing in a more general way. Monsanto still specifies the states and the combinations that may be used. What is different is that they have reported the total number ofacres in aggregate (i.e., the number of acres they are requesting includes PIP, non-PIP, and border acres) and only broke them down to the state level. Previously, Monsanto reported the number of acres per state and broke those acres down by combination and border 

### & non-PIP acres. The advantage ofthis new approach is that Monsanto will be able to make their final decision regarding how the acres will be parsed among the combinations and non-PIP & 

### border acres closer to planting while still meeting regulatory requirements. Mons anto's final report must provide the specific combinations used and the acre distribution (which would include the number ofacres for non-PIP and border). 4. Monsanto will immediately notify the EPA of any findings from the experimental uses that have a bearing on safety (i.e., EPA requires reporting of any adverse effects from the use of, or exposure to, the pesticide). Monsanto will also keep records of production, distribution and performance, and make the records available on request to any authorized officer or employee of the Environmental Protection Agency. 5. Monsanto must provide a final report within 180 days of the expiration ofthe permit. The final report must include all of the items set forth in 40 CFR 172.8(b) and provide the specific combinations used and the acre distribution (which would include the number of acres for nonPIP and border). Additionally, state-by-state breakdowns of acreage per protocol, locations per protocol and a list of specific counties where studies took place are required. Any changes to the stated program, including approved changes to study protocols must also be noted 6. Per 40 CFR 172.4(b )(v), Monsanto must provide the name and street address ofall cooperators as soon as available and prior to planting. Monsanto must record any changes to this information in an updated report and submit that report prior to planting. 7. The label submitted in connection with this application is acceptable and must accompany all shipments of seed under this EUP subsequent to receiving this approval. Labels must also be in the possession of the user at the time of application. A stamped copy is enclosed for your records. 8. This EUP is not a limited seed increase registration under section 

### 3 ofFIFRA, and plantings solely for commercial seed increase are prohibited.

Page 3 

## ofllEPA EUP No. 524-EUP-1 04 2015 Amendment/Extension Letter Shou ld you have questions or concerns regarding the issuance of this permit, please contact Mike Mendelsohn, ofthe Biopesticides and Polluti o n Prevention Division, by phone (703) 308-8715 or email at mendelsohn. mike@epa.gov. Page 4 of 11

## EPA EU P No. 524-EUP-1 04 2015 Amendment/Extension Letter Attachment 1 - Authorized PIPs, Amounts and Acreage Table I EUP PI P Events and Traits Event Trait(s) PC Code Registration S tatus MON 89034 CryiA.I05 and 006514 ; Registered Crv2Ah2 006515 MON 874 1 1 Cry3Bbl and 006580; Unregistered DvSnf7dsRNA 006566 MON 88017 Cry3Sbl 006498 Registered

MON 810 Cry lAb 006526 Registered TC 1507 CryI F 0064 81 Registered MIR 162 Vip3Aa20 006599 R egistered DAS-59122-7 Cry3 4Ab I and 006490 ; Registered Crv35Ahl 006556 

## Table 2 EUP Unregistered PIP Combinations Unregis tered: Contains MON 87411 MON 89034 X MON 8741 1 XMON880 17 XMON810 XTCI507 MON 89034 X MON 8741 1 X MON 88017 X MON 810 X TCI507 X MIRI62 MON 89034 X MON 87411 X MON 88017 X MON 810 X TC I5 07 X MIR162 X DAS -59122-7 MON 89034 X MON 8741 1 X MON 88017 X MON 810 X TCI507 X DAS-59122-7 MON 89034 X MON 8741 1 X MON 88017 X MON 810 X MIR I 62 MON 89034 X MON 8741 1 X MON 88017 X MON 810 X MIR I 62 X DAS-59 1 22 -7 MON 89034 X MON 8741 1 X MON 88017 X MON 810 X DAS-59122-7 MON 89034 X MON 87411 X MON 88017 MON 89034 X MON 87411 X MON 88017 X MON 810 MON 89034 X MON 87411 X MON 88017 X TC I507 MON 89034 X MON 87411 X MON 88017 X TCI507 X MIR I62 MON 89034 X MON 87411 X MON 88017 X TCI507 X MIRI62 X DAS-59122-7 MON 89034 X MON 8741 1 X MON 88017 X TC I 507 X DAS-59122-7 MON 89034 X MON 87411 X MON 88017 X MIRI62 MON 89034 X MON 8741 1 X MON 88017 X MIR162 X DAS-59122-7 MON 89034 X MON 87411 X MON 88017 X DAS-59122-7 MON 89034 X MON 87411 MON 89034 X MON 8741 1 X MON 810 

## Page 5 of 11EPA EU P No. 524-EUP - 104 2015 Amendment/Extension Letter Table 2 EUP Unregistered P I P Combi n ations MON 8903 4 X MON 8741 1 X MON 810 X TC 1 507 MON 89034 X MON 8741 1 X M ON 810 X TC 1 507 X MIR I 62 MON 8903 4 X MON 8741 1 X MON 810 X TCI507 X MIR 1 62 X DAS-59 1 22 - 7 MON 89034 X MON 87411 X MON 810 X TCI507 X DAS-59122 - 7 MON 89034 X MON 87411 X MON 810 X MIRI62 MON 8903 4 X MON 87411 X MON 810 X MIR162 X DAS -5 9122-7 MON 8903 4 X MON 87411 X MON 810 X DAS-59122-7 MON 8903 4 X MON 8741 1 X TC 1507 MON 89034 X MON 87411 X TCI507 X MIR I 62 MON 89034 X MON 87411 X TCI507 X MIR I 62 X DAS-59 1 22-7 MON 89034 X MON 87411 X TC1507 X DAS-59122-7 MON 89034 X MON 87411 X MIR162 MON 89034 X MON 87411 X MIRI62 X DAS-59122-7 MON 89034 X MON 87411 X DAS-59122 - 7 MON 874 1 1 X MON 88017 MON 874 1 1 X MON 88017 X MON 810 MON874 1 1 XMON880 1 7 XMON810 XTCI507 MON 8741 1 X MON 880 1 7 X MON 810 X TC1507 X M I RI62 MON 87411 X MON 88017 X MON 810 X TCI507 X MIRI62 X DAS - 59122-7 MON 8741 1 X MON 88017 X MON 810 X TCI507 X DAS -59122- 7 MON 87411 X MON 88017 X MON 810 X MIRI62 MON 87411 X MON 88017 X MON 810 X MIRI62 X DAS-59 122-7 MON 8741 1 X MON 88017 X MON 810 X DAS-5912 2-7 MON 874 1 1 X MON 88017 X TC I 507 MON 874 1 1 X MON 88017 X TC I 507 X M I RJ62 MON 87411 X MON 88017 X TCI507 X MJRI62 X DAS-59122-7 MON 8741 I X MON 880 1 7 X TCI507 X DAS-59122-7

MO N 8741 I X MON 88017 X MIR162 MON 87411 X MON 88017 X MIRI62 X DAS-59122-7 MON 87411 X MON 88017 X DAS-59122-7 MON 874 1 1 X MON 8 1 0 MON 87411 X MON 8 1 0 X TC I 507 MON 87411 X MON 810 X TCI507 X MIRI62 MON 87411 X MON 810 X TC I507 X MIR162 X DAS-59122-7

MO N 87411 X MON 810 X T CJ507 X DAS-59122-7 MO N 87411 X MON 810 X MIRI62 MON 87411 X MON 810 X MIRI62 X DAS-59122-7 Page 6 ofll

## EPA EUP No. 524-EUP-1 04 20 15 Amendment/Extension Letter T able 2 EUP Unregistered PIP Combinations MON 874 11 X MON 810 X DAS-59122-7 MON 874 11 X TCI507 MON 8741 1 X TCI507 X MIR I 62 MON 87411 X TCI507 X DAS-59122-7 MON 87411 X TCI507 X MIR 162 X DAS-59122-7 MON 87411 X MIRI62 MON 87411 X MIRI62 X DAS-59 122-7 MON 874 1 1 X DAS-59122-7 

### Unregistered: New Combinations of Registered Active Ingred ients MON 89034 X MON 88017 X MON 810 MON 89034 X MON 88017 X MON 810 X TCI507 MO 89034 X MON 88017 X MON 810 X TCI507 X MIRI62 MO 1 89034 XMON88017 XMON8 10 XTCI507 XMIR162XDAS -5 9122-7 MON 89034 X MON 88017 X MON 8 10 X TCI507 X DAS-59122-7 MON 89034 X MON 88017 X MON 810 X MIRI62 MON 89034 X MON 88017 X MON 810 X MIR162 X DAS-59 122-7 MON 89034 X MON 88017 X MON 810 X DAS-59122-7 MON 89034 X MON 88017 X TC I507 X MIRI62 MON 89034 X MON 88017 X TCI507 X MIRI62 X DAS-59122-7 MON 890 34 X MON 88017 X MIR 162 MON 89034 X MON 88017 X MIR162 X DAS-59122-7 MON 89034 X MON 810 MON 8903 4 X MON 810 X TCI507 MON 89034 X MON 810 X TCI507 X MIR162 MON 89034 X MON 810 X TCI507 X MIRI62 X DAS-59 1 22-7 MON 890 34 X MON 810 X TCI507 X DAS-59122-7 MON 890 34 X MON 810 X MIRI62 MON 89034 X MON 810 X MIRI62 X DAS-59122-7 MON 89034 X MON 8 10 X DAS-59122 -7 MON 890 34 X TC I507 X MIR162 MON 89034 X TCI507 X MIRI62 X DAS -59 122-7 MON 89034 X MIRI62 MON 89034 X MIRI62 X DAS-59122-7 MON 88017 X MON 810 X TCI507 MON 88017 X MON 810 X TCI507 X MIR162 MON 88017 X MON 810 X TC I 507 X MIR162 X DAS-59122-7



## . Page 7 ofllEPA EUP No. 524-EUP-104 2015 Amendment/Extension Letter Table 2 EUP Unregistered PIP Comb i nations MON 88017 X MON 810 X TCI507 X DAS - 59122-7 MON 88017 X MON 810 X M IRI62 MON 88017 X MON 810 X MIRI62 X DAS-59122-7 MON 88017 X MON 8 1 0 X DAS-59122-7 MON 88017 X TCI507 X MIRI62 MON88017 XTCI507 XMIR162XDAS - 59122-7 MON 88017 X MIRI62 MON 88017 X M 1 R162 X DAS - 59122-7 MON 810 X TCI507 X MIRI62 X DAS -59 1 22-7 MON 810 X MIR162 MON 810 X MIR162 X DAS - 59 1 22 - 7

TC I5 07 X MIR162 X DAS - 59122 - 7 MIR162 X DAS-59122 - 7 Table 3 Registered PIPs Combina ti on Used in EUP MON 89034 X MON 88017 (EPA Reg.N'2 524-576) MON 89034 X MON 88017 X TC I 507 (EPA Reg .N'2 524-587) MON89034 XMON88017 XTC I 507 XDAS-59122 - 7(EPARegN!! 524-581) MON 89034 X MON 88017 X DAS-59122-7 (EPA Reg .N'!! 524-589) MON 89034 X TC I5 07 (EPA Reg.N'2 524-585) MON 89034 X TC I 507 X DAS-59122-7 (EPA Reg .N'2 524-588) MON 89034 X DAS-59122-7 (EPA R eg .N'2 524-584) MON 88017 X MON 810 (EPA Reg N'2 524-552) MON 88017 X TC I 507 (EPA Reg .N'2 52 4 -583) MON 880 1 7 X TC I 507 X DAS-59122-7 (EPA R eg N'2 524-590) MON 88017 X DAS-59122-7 (EPA Reg N'!! 524-586) MON 810 X TC1507 (EPA Reg N2 29964 - 7) MON 810 X TCI507 X MIRI62 (EPA Reg N'2 29964 - 19) MON 810 X TC I 507 X DAS-59122-7 (EPA Reg N'2 29964-8) MON 810 X DAS-59122-7 (EPA RegN2 29964-9) TCIS07 X MIRI62 ( EPA Reg N'!! 29964-20) T C I5 07 X DAS-59122-7 (EPA Reg N2 29964-5) Page 8 ofll

## EPA EtJP No . 524 -EUP- 104 2015 Amendment/Extension Letter Ta ble 4 Acres by Sta te, Amount of Corn Seed (lb), and Maximum Amount of

AL 

### AR CA 

## co FL GA HI 

### lA 

### IL 

### IN 

### KS LA Ml MN 

## MO MS NC ND 

### NE OH PA 

### PR 

## sc SD TN 

### TX WA WI
Tota I 

## MON 874 11 :g, !b) that May Be Used Under thi s EUP Amount of PIP Protein Acre s2 

### Ib Seed DvSnf7dsRNA Cn:3Bb l lb grams lb 

### 2015 20 1, 200 2.04 E-06 9 .25-E-04 6 . 12E-03 10 600 1.02 E-06 4.63E-04 3.06E-03 0 0 0 0 0 5 300 5.IOE-07 2.3I E-04 1.53 E-03 10 600 1 .02E-06 4 .63E-04 3 .06E-03 II 660 1.12E-06 5 .09E-04 3.37E-03 753 45, 180 7.68E-05 3 .48E-02 0.230 829 49 ,740 8.46£ -05 3 .84£ - 02 0 .254 952 57 , 120 9.71 E-05 4 .40E-02 0 . 291 1 48 8 , 880 1.51 E-05 6.85E-03 4 .53E-02 323 19,380 3 .29E-05 1.49E-02 9.88E- 02

II 660 1.12£-06 5. 09 £ -04 3.37E- 03 0 0 0 0 0 172 10, 320 1.75E-0 5 7.96E-03 5.26E-02 10 600 1 .02E-Op 4.63 E-04 3.06E-03 75 4, 500 7 .65E-06 3.47E-03 2.30E-02 13 780 1.33 E-06 6 .01 E-04 3.98E-03 16 960 1.63E-06 7.40E- 04 4.90E-03 333 1 9, 980 3.40E- 05 1.54E-02 0. 1 02 8 480 8 . 16E- 07 3 .70E-04 2.45 E-03 3 180 3 .06E-07 1. 39E-04 9.18E-04 605 36 ,300 6.17E- 05 2.80£ -02 0 . 185 10 600 1.02E-06 4.63E-04 3.06E-03 6 360 6 . 12E-07 2.78E-04 1. 84 E-03 88 5,280 8 .98E-06 4.07E-03 2.69E-02 3 1 1, 860 3.16E- 06 1.43E-03 9.49E-03 150 9 , 000 1.53E-05 6.94E-03 4.59E-02 5 300 5.10E- 07 2.31E-04 1. 53E-03
4 , 597 275 , 820 4 .69E-04 0 .213 1.4 1 grams 2 . 78 1.39 0 0.694 1.39 1.5 3 105 1 15 132 20 .5 44 .8 1. 53

0 23.9 1.39 10.4 1.80 2.22 46.2 1.11 0 .416 84.0 1.39 0 . 833 12.2 4 .30 20.8 0 .694 638

2 

### T hese proposed values represent the maximum possible acres and seed to be used in each state and in total. T hese values reflect maximum MON 87411 acres and may be comprised of any combination of PIP, non -PIP , and border materials. 

## Page 9 ofllEPA EUP No. 524 - EU P-1 04 20 15 Amendment/Extension L ette r Table 4 Acres by Sta t e, Amount of Com Seed (lb), and Maxim u m Amount of AL AR CA c o FL GA H l A IL I N KS L A M

I I MN MO MS NC ND NE OH PA P R sc S D TN TX WA WI Tota I

MON 874 1 1 : g, l b) t h at M a y Be Use d Under this EUP Amount of PI P Protein Acres 2 lb Seed DvSnf7d sRNA CrY3Bb1 lb grams lb 20 1 6 1 08 6 , 480 1.10£ - 05 5 . 00£-03 3.30£-02 1 00 6 ,000 1.02 £ - 05 4 .63£ - 03 3 . 06E-02 12 720 1 . 22 £ -06 5.55£-04 3.67E -0 3 50 3,000 5. 1 0£-06 2.31£-03 1.53 E-02 100 6 , 000 1.02£ - 05 4 . 63£-03 3.06E-02 401 24,060 4.09£-05 1 .86E-02 0.123 903 54 , 1 80 9 .2 1E-05 4.18E-02 0 .276 446 26 , 760 4. 55E-05 2 .06£- 02 0.136 246 1 4 , 760 2.51 £ -05 1.14 £ -02 7 . 53E-02 122 7,320 1 . 24E - 05 5.64£-03 3.73E - 02 265 15 , 900 2.70£-05 1.23E-02 8 . 11 £ - 02

1 0 1 6 , 060 1.03E-05 4.67E-03 3 . 09£-02 100 6 , 000 1 .02£-05 4 . 63£-03 3 . 06 £ - 02 100 6 , 000 1. 02£-0 5 4 . 63£-03 3 . 06 £ - 02 40 2 , 400 4.0 8£ - 06 1 . 85E-03 1.22£-02 244 14 , 640 2.49E-05 1.13£-02 7.47£-02

1 05 6 , 300 1.07E-05 4 . 86£-03 3 . 21£-02 13 7 80 1.33£-06 6 . 0 1 £ - 04 3 . 98£ - 03 24 1 14 ,4 60 2 . 46£ - 05 1.12 £-02 7 . 37E - 02 1 0 600 1.02£-06 4.63£-04 3 . 06£-03 5 300 5 . 10£ - 07 2.31£-04 1.53£-03 507 30,420 5 .17£-05 2 .3 5E-02 0. 1 55 100 6,000 1 .02E - 05 4 .63E -03 3.06E-02

6 360 6.12£-07 2.78£ -04 1 .8 4 E -0 3 103 6 , 1 80 1 . 05E-05 4 . 77E-03 3.15E-02 216 12 ,9 60 2 . 20 E - 05 9.99E-03 6.61£-02 305 18 , 300 3. 1 1 £-05 1.41 E-02 9 . 33E - 02 10 600 1.02£-06 4.63E -04 3 . 06E - 03 4.959 297 , 540 5 .06 E- 04 0 . 229 1.52 P a ge 1 0 o f 11

grams 15 .0 13 . 9 1.67 6 . 94 13.9 55 . 7 125 61.9 34.1 1 6.9 36.8 14. 0 13.9 13.9 5 . 55 33.9 14.6 1.80 33.5 1.390 . 694 70 .4 13.9 0.833 14 . 3 30.0 42.3 1.39 688

## EPA EUP No. 524-EUP-104 2015 Amendment/Extension Letter T

able 4 Acres by State, Amount of Com Seed (lb), and Maximum Amount of

AL 

### AR CA 

# co FL GA 

### HI lA IL 

### IN 

### KS LA 

### Ml MN 

### MO MS NC ND 

### NE OH PA 

### PR 

# sc SD TN 

### TX WA WI 

### Total 

## MON 87411 (g, lb) that May Be Used Under this EUP Amount ofPIP Protein Acres 2 

### lb Seed DvSnf7dsRNA Ca3Bb1 lb grams lb GRAND TOTAL 128 7,680 1 .31E-05 5 .92E-03 3 .92E-02 110 6,600 1.12E- 05 5.09E-03 3.37E-02 12 720 1.22E-06 5.55E-04 3.67£-03 55 3,300 5.61E- 06 2.54E-03 1.68 £ -02 110 6,600 1 . 12E-05 5.09E-03 3.37E-02 412 24,720 4.20E- 05 1.9 1E-02 0 . 126 1,656 99,360 1.69E-04 7.66E-02 0.507 1, 275 76,500 1.30E-04 5.90E- 02 0.390 1,198 71 ,8 80 1.22E- 04 5 . 54E-02 0.367 270 16,200 2.75E-05 1.25E-02 8 .26E-02 588 35,280 6.00E- 05 2.72E-02 0.180 1 12 6,720 1.14E-05 5 .18E-03 3.43E-02 100 6 ,000 1 .02 E-05 4 .63E-03 3 .06£-02 272 16,320 2.77E-05 1.26E-02 8.32E-02 50 3,000 5 . 10E-06 2 .31E-03 1.53E-02 3 19 19,140 3 . 25E-05 1.48E-02 9 .76£-02 1 18 7,080 1.20£-05 5.46E- 03 3 .61E-02 29 1,740 2.96E-06 1.34E-03 8.87E-03 574 34,440 5.85E-05 2 .66E- 02 0.176 18 1,080 1.84E-06 8.33 E -04 5 . 51 E-03 8 480 8.16E-07 3 .70E-04 2 .45E-03 1,112 66,720 1. 13E-04 5. 14E- 02 0 . 340 110 6,600 1.12E-05 5.09£ - 03 3.37E- 02 12 720 1. 22E-06 5 .55£-04 3.67E-03 191 1 1,460 1 .95E-05 8 .84£-03 5.84E-02 247 14,820 2 . 52E-05 1. 14E-02 7.56E-02 455 27,300 4 .64E-05 2.11E-02 0.139 15 900 1.5 3E-06 6.94E-04 4.59E-03 9,556 573,360 9.75E-04 0.442 2 .92



## Page 11 of 11 grams 17 . 8 15.3 1.67 7.63 15.3 57.2 230 177 166 37.5 8 1. 6 15.5 13.9 37 .8 6.94 44 .3 1 6 .4 4.03 79 .7 2 . 50 1.1 1 154 15 .3 1. 67 26 . 5 34.3 63 .2 2 . 08 1,326