Exhibit 10.77


 


THE SECURITIES OFFERED HEREBY HAVE NOT BEEN
AND WILL NOT BE REGISTERED WITH THE UNITED STATES SECURITIES AND EXCHANGE COMMISSION, OR THE SECURITIES COMMISSION OF ANY STATE
PURSUANT TO AN EXEMPTION FROM REGISTRATION PROVIDED BY SECTION 3(b) OF THE SECURITIES ACT OF 1933, AS AMENDED, AND THE RULES AND
REGULATIONS PROMULGATED THEREUNDER (THE “1933 ACT)


 


US $1,388,888.89


 


NORTHWEST BIOTHERAPEUTICS, INC


6% CONVERTIBLE SECURED FULL RECOURSE REDEEMABLE
NOTE


DUE AUGUST 25, 2018


 


FOR VALUE RECEIVED, Northwest
Biotherapeutics, Inc. (the “Company”) promises to pay to the order of Adar Bays, LLC and its authorized successors
and permitted assigns (“Holder”), the aggregate principal face amount of One Million Three Hundred and Eighty
Eight Thousand, Eight Hundred and Eighty Eight Dollars and Eighty Nine Cents (U.S. $1,388,88.89) on August 25, 2018 (“Maturity
Date”), including a 10% OID of One Hundred and Thirty Eight Thousand, Eight Hundred and Eighty Eight Dollars and Eighty
Nine Cents ($188,888.89) and to pay interest on the principal amount outstanding hereunder at the rate of 6% per annum commencing
on May 1, 2018. Upon execution of the Note, Holder shall wire to Company $1,250,000, subject to Paragraph 13 below. Interest will
be paid to the Holder in whose name this Note is registered on the records of the Company regarding registration and transfers
of this Note. The principal of, and interest on, this Note are payable at 1619.2 Coastal Highway, Lewes, DE, 19958 initially, and
if changed, last appearing .on the records of the Company as designated in writing by the Holder hereof from time to time. The
Company will pay each interest payment and the outstanding principal due upon this Note before or· on the Maturity Date,
less any amounts required by law to be deducted or withheld, to the Holder of this Note by check or wire transfer addressed to
such Holder at the last address appearing on the records of the Company. The forwarding of such check or wire transfer shall constitute
a payment of outstanding principal hereunder and shall satisfy and discharge the liability for. principal on this Note to the extent
of the sum represented by such check or wire transfer. Interest shall be payable in Common Stock (as defined below) pursuant to
paragraph 4(b) herein.


 


This Note is subject to the following additional provisions:


 




     


     


    

 


1.          This
Note is exchangeable for an equal aggregate principal amount of Notes of different authorized denominations, as requested by the
Holder surrendering the same. No service charge will be made for such registration or transfer or exchange, except that Holder
shall pay any tax or other governmental charges payable in connection therewith.


 


2.          The
Company shall be entitled to withhold from all payments any amounts required to be withheld under applicable laws.


 


3.          This
Note may be transferred or exchanged only in compliance with the Securities Act of 1933, as amended (“Act”) and applicable
state securities laws. Any attempted transfer to a non-qualifying party shall be treated by the Company as void. Prior to due presentment
for transfer of this Note, the Company and any agent of the Company may treat the person in whose name this Note is duly registered
on the Company’s records as the owner hereof for all other purposes, whether or not this Note be overdue, and neither the
Company nor any such agent shall be affected or bound by notice to the contrary. Any Holder of this Note electing to exercise the
right of conversion set forth in Section 4(a) hereof, in addition to the requirements set forth in Section 4(a), and any prospective
transferee of this Note, also is required to give the Company written confirmation that this Note is being converted (“Notice
of Conversion”) in the form annexed hereto as Exhibit A. The date of receipt (including receipt by telecopy) of
such Notice of Conversion shall be the Conversion Date.


 


4.          (a)          Upon
the occurrence of an Event of Default, the Holder of this Note is entitled, to convert all or any amount of the principal face
amount of this Note then outstanding into shares of the common stock of Northwest Biotherapeutics, Inc. (the “Common Stock”)
without restrictive legend of any nature, at a conversion price (“Conversion Price”) for each share of Common
Stock equal to equal to 90% of the average price comprised of the average of the daily volume weighted average prices (the “VW
AP”), as reported on the National Quotations Bureau (OTCBB) on which the Common Stock is traded or any exchange upon
which the Common Stock may be traded in the future (“Exchange”), for the five (5) trading days with the lowest
VWAPs during the fifteen (11). trading days immediately preceding the Conversion Date, including the day upon which a Notice of
Conversion is received by the Company, provided such Notice of Conversion is delivered by fax to the Company between the hours
of 4 P.M. Eastern Standard or Daylight Savings Time and 8 P.M., Eastern Standard or Daylight Savings Time. provided such Notice
of Conversion is delivered by fax to the Company between the hours of 4 P.M. Eastern Standard or Daylight Savings Time and 8 P.M.
Eastern Standard or Daylight Savings Time. Such conversion shall be effectuated by the Company and/or Northwest Bi-otherapeutics
delivering the shares of Common Stock to the Holder within two (2) business days of receipt by the Company of the Notice of Conversion
(the “Grace Period”). If the Holder has not received the aforementioned shares of Common Stock within 4 business days
from the delivery of a Notice of Conversion to the Company and/or the transfer agent, then a penalty payment of $250 per day shall
be added to the outstanding balance of this Note after Grace Period until the Holder has received the Common Stock. Once the Holder
has received such shares of Common Stock, the Holder shall surrender this Note to the Company, executed by the Holder evidencing
such Holder’s intention to convert this Note or a specified portion hereof, and accompanied by proper assignment hereof in
blank. Accrued but unpaid interest shall be subject to conversion. No fractional shares or scrip representing fractions of shares
will be issued on conversion, but the number of shares issuable shall be rounded to the nearest whole share. In no event shall
the Holder be allowed to effect a conversion if such conversion, along with all other shares of Company Common Stock beneficially
owned by the Holder and its affiliates would exceed 4.99% of the outstanding shares of the Common Stock of the Company (which may
be increased up to 9.9% upon 60 days’ prior written notice by the Investor). All the terms set forth herein, including but
not limited to interest rate, prepayment terms, conversion discount, shares reserves or lookback period will be adjusted downward
(i.e. for the benefit of the Holder) if the Company offers a more favorable conversion discount (whether via interest, rate OID,
warrants, restricted shares, reserves or otherwise) or lookback period to another party or otherwise grants any more favorable
terms to any third party than those contained herein while this note is in effect. All remedies herein are cumulative.


 




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(b)          Interest
on any unpaid principal balance of this Note shall be paid at the rate of 6% per annum. Interest shall be paid by the Company in
Common Stock (“Interest Shares”). The Holder may, at any time, send in a Notice of Conversion to the Company for Interest
Shares based on the formula provided in Section 4(a) above. The dollar amount converted into Interest Shares shall be all or a
portion of the accrued interest calculated on the unpaid principal balance of this Note to the date of such notice.


 


(c)          This
Note may not be prepaid.


 


(d)          In
case of any Sale Event in connection with which this Note is not redeemed or converted, the Company shall cause effective provision
to be made so that the Holder of this Note shall have the right thereafter, by converting this Note, to purchase or convert this
Note into the kind and number of shares of stock lir other securities or property (including cash) receivable upon such reclassification,
capital reorganization or other change, consolidation or merger by a holder of the number of shares of Common Stock that could
have been purchased upon exercise of the Note and at the same Conversion Price, as defined in this Note, immediately prior to such
Sale Event. The foregoing provisions shall similarly apply to successive Sale Events. If the consideration received by the holders
of Common Stock is other than cash, the value shall be as determined by the Board of Directors of the Company or successor person
or entity acting in good faith.


 


5.           
No provision of this Note shall alter or impair the obligation of the Company, which is absolute and, unconditional, to pay
,the principal of, and interest on; this Note at the time, place, and rate, and in the form, herein prescribed.


 


6.             The
Company hereby expressly waives demand and presentment for payment, notice of non-payment, protest, notice of protest, notice of
dishonor, notice of acceleration or intent to accelerate, and diligence in taking any action to collect amounts called for hereunder
and shall be directly and primarily liable for the payment of all sums owing and to be owing hereto.


 


7.             The
Company agrees to pay all costs and expenses, including reasonable attorneys’ fees and expenses, which may be incurred by
the Holder in collecting any amount due under this Note.


 




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8.             If
one or more of the following described “Events of Default” shall occur:


 


(a)           The
Company shall default in the payment of principal or interest on this Note or any other note issued to the Holder by the Company;
or,


 


(b)          Any
of the representations or warranties made by the Company herein or in any certificate or financial or other written statements
heretofore or hereafter furnished by or on behalf of the Company in connection with the execution and delivery of this Note shall
be false or misleading in any respect; or


 


(c)           The
Company shall fail to perform or observe, in any respect, any covenant, term, provision, condition, agreement or obligation of
the Company under this Note; or


 


(d)           The
Company shall (1) become insolvent; (2) admit in writing its inability to pay its debts generally as they mature; (3) make an assignment
for the benefit of creditors or commence proceedings for its dissolution; (4) apply for or consent to the appointment of a trustee,
liquidator or receiver for its or for a substantial part of its property or business; (5) file a petition for bankruptcy relief,
consent to the filing of such petition or have filed against it an involuntary petition for bankruptcy relief, all under federal
or state laws as applicable; or


 


(e)          A
trustee, liquidator or receiver shall be appointed for the Company or for a substantial part of its property or business without
its consent and shall not be discharged within thirty (30) days after such appointment; or


 


(f)           Any
governmental agency or any court of competent jurisdiction at the instance of any governmental agency shall assume custody or control
of the whole or any substantial portion of the properties or assets of the Company; or


 


(g)          One
or more money judgments, writs or warrants of attachment, or similar process, in excess of Two Million dollars ($2,000000) in
the aggregate, shall be entered or filed against the Company or any of its properties or other assets and shall remain
unpaid, unvacated, unbonded or unstayed for a period of fifteen (15) days or in any event later than five (5) days prior to
the date of any proposed sale thereunder; or


 


(h)          Bankruptcy,
reorganization, insolvency or liquidation proceedings, or other proceedings for relief under any bankruptcy law or any law for
the relief of debtors shall be instituted voluntarily by or involuntarily against the Company; or


 


(i)          Northwest
Biotherapeutics shall have its Common Stock delisted from any current exchange it is now on, or, if the Common Stock trades on
an exchange, then trading in the Common Stock shall be suspended for more than 10 consecutive days;


 


(j)          If
a majority of the members of the Board of Director of the Company on the date hereof are no longer serving as members of the Board;
or


 




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The Company shall not
deliver to the Holder the Common Stock pursuant to paragraph 4 herein without restrictive legend within 4 business days of its
receipt of a Notice of Conversion.


 


Then, or at any time thereafter, unless cured,
and in each and every such case, unless such Event of Default shall have been waived in writing by the Holder (which waiver shall
not be deemed to be a waiver of any subsequent default) at the option of the Holder and in the Holder’s sole discretion,
the Holder may consider this Note immediately due and payable, without presentment, demand, protest or (further) notice of any
kind (other than notice of acceleration), all of which are hereby expressly waived, anything herein or in any note or other instruments
contained to the contrary notwithstanding, and the Holder may immediately, and without expiration of any period of grace, enforce
any and all of the Holder’s rights and remedies provided herein or any other rights or remedies afforded by law. Upon an
Event of Default, interest shall be accrue at a default interest rate of 18% per annum or, if such rate is usurious or not permitted
by current law, then at the highest rate of interest permitted by law.


 


If the Holder shall commence an action or proceeding
to enforce any provisions of this Note, including without limitation engaging an attorney, then the Holder shall be reimbursed
by the Company for its attorneys’ fees and other costs and expenses incurred in the investigation, preparation and prosecution
of such action or proceeding. The principal executive officers of the Company shall be personally responsible for all such fees
and expenses.


 


9.            In
case any provision of this Note is held by a court of competent jurisdiction to be excessive in scope or otherwise invalid or unenforceable,
such provision shall be adjusted rather than voided, if possible, so that it is’ enforceable to the maximum extent possible,
and the validity and enforceability of the remaining provisions of this Note will not in any way be affected or impaired thereby.


 


10.          Neither
this Note nor any term hereof may be amended, waived, discharged or terminated other than by a written instrument signed by the
Company and the Holder.


 


11.          This
is a full recourse note and the Holder may have other remedies avail-able by law.


 


12           This
Note shall be governed .by and construed in accordance with the laws of New York applicable to contracts made and wholly to be
performed within the State of New York and shall be binding upon the successors and assigns of each party hereto. The Holder and
the Company hereby mutually waive trial by jury and consent to exclusive jurisdiction and venue in the courts of the State of New
York. This Agreement may be executed in counterparts, and the facsimile transmission of an executed counterpart to this Agreement
shall be effective as an original.


 


13.          The
Company will pay legal fees incurred by the Holder in the negotiation of this note and the transactions related thereto, in the
amount of $50,000.00, the proceeds of which shall be deducted from the $1,250,000 amount to be wired the Company upon closing.


 




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IN
WITNESS WHEREOF, the Company has caused this Note to be duly executed by an officer thereunto duly authorized.


 


Dated: May 1, 2018


 


	 	NORTHWEST BIOTHERAPEUTICS, INC.
	 	 	 
	 	By:	/s/  Leslie J. Goldman
	 	Name:  Leslie J. Goldman
	 	Title: Senior Vice President


 




     


     


    

 


EXHIBIT A


 


NOTICE OF CONVERSION


 


(To be Executed by the Registered Holder in
order to Convert the Note)


 


The undersigned hereby irrevocably elects to
convert $ ____________ of the above Note into ____________ Shares of Common Stock of Northwestern Biotherapeutics, Inc.
(“Shares”) according to the conditions set forth in such Note, as of the date written below.


 


If Shares are to be issued in the name of a
person other than the undersigned, the undersigned will pay all transfer and other taxes and charges payable with respect thereto.


 


	Date of Conversion:  	 



	Applicable Conversion Price:	 



	Signature:	[Print Name of Holder and Title of Signer]



	Address:	 
	 	 


 


SSN or EIN: ______________________________


Shares are to be registered in the following name:


 


	Name:	 



Address:


Tel: _______


Fax: _______


 


SSN or EIN:


 


Shares are to be sent or delivered to the following account:


 


	Account Name:  	 



Address: