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### UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

**WASHINGTON, D.C. 20460**
**OFFICE OF CHEMICAL SAFETY AND**  **POLLUTION PREVENTION** 

### MEMORANDUM **Date:** 15

- May

- 2014 **Subject: Bifenazate**  **(000586); Acute and**  **Chronic Dietary Exposure and Risk**  **Assessment.**

Section 3 Registration Request to Add New Uses on Timothy Forage and Hay ; Herb, Subgroup 19A; and to Expand Existing Uses on Pome Fruit, Group 11, and Fruiting Vegetables, Group 8.
**PC Code:** 000586 **DP Barcode :**  D 388801 **Decision No.:** 446177 **Registration Nos. :**  400

- 503, 400

- 514 **Petition No.:** 1E7847 **Regulatory Actions:** Section 3 Registration **Risk Assessment Type:** Dietary **Case No.:** 7609 **T XR No.:**  NA **CAS No.:** 149877

- 41

- 8 **MRID No.:** none **40 CFR:** §180.572 

### Reviewer: William D. Wassell, Chemist

R isk Assessment Branch 1 (RAB1) Health Effects Division (HED, 7509P) **Through:** Sheila Piper , Chemist

Mohsen Sahafey en , Chemist Dietary Exposure Science Advisory Council (DESAC) H ED (7509P) and George F. Kramer, Ph.D., Branch Senior Chemist RAB1/HED (7509 P ) **To:** William D. Wassell, Risk Assessor

RAB1/HED (7509P) and Barbara Madden, RM 05 Registration Division (RD; 7505P) **Executive Summary** RD has requested HED to perform a dietary exposure and risk anal ys is for bifenazate to support uses on herbs, timothy , and to expand existing uses on Pome Fruit, Group 11, and Fruiting Vegetables, Group 8 to include additional commodities in the expanded crop groups. Acute and c hronic dietary (food plus drinking water) exposure and risk assessment s were conducted using the Dietary

Exposure Evaluation Model

- Food Consumption I ntake Database (DEEM

- FCID ), Version 3.16, which uses food consumption data from the U.S. Department of Agriculture’s (USDA’s) National Health and Nutrition Examination Survey , What We Eat in America,Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

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### (NHANES/WWEI A). This dietary survey was conducted from 2003 to 2008. The anal ys es were conducted in support of a human

- health risk assessment for the proposed Section 3 registratio n request to add uses on t imothy , Herb, Subgroup 19A; and to e xpand e xisting u ses on Pome Fruit, Group 11, and Fruiting Vegetables, Group 8. This memorandum was reviewed b y two peer reviewers of the DESAC per the current DESAC Standard Operating Procedure s (SOP). Acute Dietary

Exposure Assessment The acute anal ys is for the g eneral p opulation, including infants and children , was unrefined and used tolerance

- level residues and 100% crop

- treated (PCT)

. The acute analy s i s for females 13 to 49 ye ars old w as highl y refined and incorporated data from the USDA’s Pesticide Data Program (PDP) , crop field trial data, and PCT estimates (provided by the Biological Economic Anal ys is Division (BEAD); 0 5 / 04 /20 12). DEEM ( ver. 7.81 ) default processing factors were assumed for all commodities excluding apple juice, grape juice, and wine/sherry . The processing factors for these commodities were reduced to 1.0 , based on data from processing studies. The anal ys es also included the acu te surface water point estimate generated using the Food Quality Protection Act ( FQPA ) Index Reservoir Screening Tool (FIRST) and the dry bean application scenario (2 x 0. 75 lb ai/acre; 14

- day

retreatment interval (RTI); highest registered/proposed use rat e). The acute risk estimate utilizes <1 % (0.0 40436 mg/kg/day ) of the acute population

- adjusted dose ( a PAD ) for the U.S. p opulation at the 95 th 

### percentile of exposure

. T he most highly

- exposed population subgroup was children 1 to 2 y ears old which utilized 1. 9 % (0. 113582 mg/kg/day ) of the a PAD at the 95 th 

### percentile of exposure

. The acute risk estimate utilizes 9.9 % (0.0099 41 mg/kg/day ) of the aPAD for females 13 to 49 y ears old at the 99 .9 th 

### percentile of exposure. Thus, acute dietary exposure to bifenazate for all population subgroups is not of concern

. Chronic (Non

- cancer) Dietary Exposure Assessment The chronic dietary

exposure anal ys is for the all population subgroups was partially refined and used tolerance

- level residues and P CT estimates

. DEEM (ver. 7.81 ) default processing factors were assumed for all commodities excluding apple juice, grape juice, and wine/sherry . The processing factors for these commodities were reduced to 1.0 based on data from processing studies. The anal ys es also included the chronic surface water point estimate generated using the FIRST and the dry bean application scenario (2 x 0.75 lb ai/acre; 14

- day RTI; highest registered/proposed rate). The chronic risk estimate utilizes 2 4 % (0.002 360 mg/kg/da y) of the chronic population

- adjusted dose (cPAD) for the U.S. population. The most highl y - exposed population subgroup was children 1 to 2 y ears old which utilized 7 4 % (0.007 438 mg/kg/day ) of the cPAD. Thus, chronic dietary exposure to bifenazate for all population subgroups is not of concern. Chronic (Cancer) Dietary Exposure Assessment Bifenazate is classified as "not likely " to be a human carcinogen. Therefore, a cancer dietary exposure assessment is not required.Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

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### I. **Introduction** Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose (i.e., the dose that HED has concluded will result in no unreasonab le adverse health effects). This dose is referred to as the population

- adjusted dose (PAD). The PAD is equivalent to the point of departure (POD, NOAEL, LOAEL, e.g.) divided b y the required uncertainty or safety factors. The most recent ( previous ) dietary

exp osure assessment for bifenazate was performed o n 05/25/2010 ( D 371941, W. Wassell). **II. Residue Information**  Residues of Concern in Plants, Livestock, and Drinking W ater: Table 1 is a summary of the HED Metabolism Assessment Review Committee (MARC) decisions concerning the residues of concern in plants, livestock, rotational crops, and drinking water (D276801, T. Bloem, 8/16/ 2001; D290053, T. Bloem, 5/ 29 / 2003).
**Table 1. Residues for Tolerance Expression and Risk Assessment**  **.**

**Matrix Residues**  **Included in Risk Assessment**  **Residues Included**  **in Tolerance Expression** Pla nts bifenazate, D3598 (expressed as parent) bifenazate, D3598 (expressed as parent) Livestock (excluding fat) bifenazate, D3598 (expressed as parent), A1530, A1530

- sulfate (expressed as A1530) bifenazate, D3598 (expressed as parent), A1530, A1530

- sulfate (expressed as A1530) Livestock

– fat bifenazate, D3598 (expressed as parent) bifenazate, D3598 (expressed as parent) Rotational Crops could not be determined 1 could not be determined 1 Drinking Water D1989 Not applicable 1 B ased on the results of the confined rotational crop study conducted at 0.5 lb ai/acre ( the application rate for the registered crops which are likely to be rotated ) , HED concluded that residues in rotated crops were unlikely and that tolerances were unnecessary . 

### Note: The residues of concern for plant commodities are bifenazate and its metabolite D3598. Residues of D3598 were include d in the tolerance expression because the enforcement method determines residues of bifenazate and D3598 as bifenazate. The metabolite was not a major residue in the submitted plant metabolism studies. Therefore, the PDP data (which monitored for bifenaz ate onl y) were not adjusted to account for residues of D3598. Established/Recommended Tolerances: Bifenazate is currentl y registered for application to various commodities with tolerances ranging from 0.1 to 35 ppm (40 CFR 180.572(a)(1)). Section 18 registrations have also been established for application of bifenazate to timothy with tolerances of 50 and 150 ppm for residues in/on forage and hay , respectivel y. Tolerances, as a result of secondary residue s , are established in milk, ruminant meat, ruminant fat, and ruminant meat by products at 0.02 to 0.10 ppm (40 CFR 180.572(a)(1) and (a)(2)). As part of the current action , HED recommended for the establishment of the following tolerances for the combined re sidues of bifenazate and D3598:Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

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### Commodity **Proposed Tolerance** Herb Subgroup 19A, fresh leaves 30 ppm Herb Subgroup 19A, dried leaves, except chervil, dried , and chive, dried 140 ppm Fruit, Pome, Group 11

- 10 0.75 ppm Vegetable, Fruiting, Group 8

- 10 2.0 ppm Timothy , forage 200 ppm Timothy , hay 150 ppm Plant/Livestock Residues Used in the Acute Risk Assessments: The acute analy ses for the general population (including infants and children) incorporated established/recommended tolerance

- level resid ues for all registered/proposed crops in cluding milk and livestock commodities. The acute anal ys es for females 13 to 49 y ears old incorporated PDP data, crop field trial data , and PCT estimates

. DEEM (ver. 7.81) default processing factors were assumed for all commodities excluding apple juice, grape juice, and wine/sherry . The processing factors for these commodities were reduced to 1.0 based on data from processing studies. Plant/Livestock Residues Used in the Chronic Risk Assessments: The chronic anal ys es incorporated established/recommended tolerance

- level residues for all registered / proposed crops in cluding milk and livestock commodities and P CT data

. DEEM (ver. 7.81 ) default processing f actors were assumed for all commodities excluding apple juice, grape juice, and wine/sherry . The processing factors for these commodities were reduced to 1.0 based on data from processing studies. Fish: The USDA PDP monitored pesticide residues in cat fish in 2008, 2009, and 2010. Over this three

- ye ar period, PDP analy zed 1478 samples of catfish for bifenazate residues. None of the samples contained detectable residues. As a result, residues in fish were not included in the assessment. **III. Percent**  **Crop -**  **treated Information:** Maximum and average percent crop treated information, provided by BEAD, were used in the exposure assessment s . The PCT estimates used in the anal ys is are summarized below and in Attachment 3. The following maximum PCT estima tes ( Memo, 5/16/12, C. Doucoure, D401788 ) were used in the acute dietary

risk assessment : almonds: 10%; apples: 5%; apricots: 10%; beans, green: 2.5%; caneberries: 30%; cantaloupes: 2.5%; cherries: 5%; cucumbers: 5%; grapefruit: 5%; grapes: 20%; nectarines: 10%; oranges: 2.5%; peaches: 20%; pears: 30%; pecans: 2.5%; peppers: 10%; pistachios: 2.5%; plums/prunes: 20%; potatoes: 5%; pumpkins: 5%; squash: 2.5%; strawberries: 65%; tomatoes: 10%; walnuts: 5%; and watermelon: 2.5%. The following average PCT estimates were used in the chronic dietary risk assessment : almonds: 5%; apples: 5%; apricots: 5%; beans, green: 1%; caneberries: 25%; cantaloupes: 1%; cherries: 2.5%; cucumbers: 2.5%; grapefruit: 5%; grapes: 10%; nectarin es: 5%; oranges: 1%; peaches: 10%; pears: 15%; pecans: 1%; peppers: 5%; pistachios: 2.5%; plums/prunes: 5%; potatoes: 5%; pumpkins: 2.5%; squash: 1%; strawberries: 45%; tomatoes: 5%; walnuts: 2.5%; and watermelon: 1%.Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

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### IV. **Drinking Water Data:**  The drinking water residues used in the dietary risk assessment were provided by the Environmental Fate and Effects Division (EFED) in the following memorandum: “Drinking Water Assessment to Support Bifenazate Use on Herb Subgroup 19A, Fruiting Veg etable Group 8

- 10, Pome Fruit Group 11

- 10, and Timothy

Grass” (10/17/11, J. Hetrick, D388230) and incorporated directl y into this dietary assessment. Water residues were incorporated in the DEEM

- FCID into the food categories “water, direct, all sources” and “water, indirect, all sources.” Surface and ground water estimated drinking water concentrations (E DWC s) were generated using the FIRST and screening concentration in ground water ( SCI

- GROW ) models, respectivel y. Both models were ru n using the dry bean application scenario (2 x 0. 75 lb ai/acre; 14

- day RTI ; highest registered/proposed rate). The resulting chronic E DWC s in ground and surface water were 0.0 0001 4 pp m (30

- ye ar - annual average) and 0.0112 pp m (annual average) , respectivel y (EFED M emo; 10/17/2011, J. Hetrick; D388230)

. The resulting acute EDWC (daily peak) was 0.0373 ppm. **Table 2. Bifenazate Estim**  **ated Drinking Water Concentrations.**

**Exposure Scenario EDWC (ppm)**  30

- year Annual Average (not used) 0.000014 Annual Average (used in chronic analysis) 0.0112 Daily Peak (used in acute analysis) 0.0373 

### V **. Program and Consumption Information**  Acute and chronic dietary (food plus drinking water) exposure and risk assessment s w ere conducted using the DEEM

- FCID, Version 3.16, which uses food consumption data from the USDA’s NHANES/WWEI A. This dietary survey was conducted from 2003 to 2008. The data are based on the reported consumption of more than 20,000 individuals over two non

- consecutive survey day s. Foods “as consumed” (e.g., apple pie) are linked to EPA

- defined food commodities (e.g., apples, peeled fruit

- cooked; fresh or N/S; baked; or wheat flour

- cooked; fresh or N/S, baked) using publicly available recipe translation files developed jointly by USDA/ARS and EPA. For chronic exposure assessment, consumption data are averaged for the entire U.S. population and within population subgroups. However, for acute exposure assessment, consumption data are retained as individua l consumption events. Based on anal ys is of the 2003

- 2008 WWEIA consumption data, which took into account dietary patterns and survey

respondents, HED concluded that it is most appropriate to report risk for the following population subgroups: the general U.S. population, all infants (<1 ye ar old), children 1

- 2, children 3

- 5, children 6

- 12, y outh 13

- 19, adults 20

- 49, females 13

- 49, and adults 50

- 99 ye ars old. For an acute exposure and risk assessment, individual one

- day food consumption data are used on an individual

- by

- individual basis. The reported consumption amounts of each food item can be multiplied by

a residue point estimate and summed to obtain a total daily pesticide exposure for a deterministic exposure assessment, or “matched” in multiple rando m pairings with residue values and then summed in a probabilistic assessment. The resulting distribution of exposures is expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating relevant commodities/food forms) and a per

- capita (i.e., those who reported eating the relevant commodities as well as those who did not) basis. I n accordance with HED policy , per capita exposure and risk are reported for analy ses performed at all levels of refinement. However, for deterministicBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

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### assessments, an y significant differences in user vs. per capita exposure and risk are specificall y identified and noted in the risk assessment. For a chronic dietary

exposure and risk assessment, an estimate of the residue level in each food or food

- form (e.g., orange or orange juice) on the food commodity residue list is multiplied by the average dail y consumption estimate for that food/food form to produce a residue intake estimate. The resulting residue intake estimate for each food/food form is summed with the residue intake estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated exposure. Exposure is expressed in mg/kg bod y weight/day and as a percent of the cPAD. This procedure is performed for each population subgroup. **V I**  **. Toxicological Information** A summary

of the toxicological doses and endpoints selected for dietary exposure assessment is provided in Table 3

. **Table 3**  **. Toxicological Endpoints for Dietary Analysis .**  **Exposure Scenario**  **Dose Used in Risk** 

**Assessment FQPA SF and** 

**Uncertainty Factors Study and Toxicological Effects** 

Ac ute Dietary; (all populations) NOAEL = 600 mg/kg/day **Acute RfD = 6 m**  **g/kg/day aPAD = 6 m**  **g/kg/day** UF A = 10x UF H = 10x FQPA SF = 1x **Acute Neurotoxicity Screening Battery**  **- Rats** 

LOAEL = 2000 mg/kg/day based on decreased mo tor activity (rearing in females)

.

Ac ute Dietary; (Fem ales 13 to 49 years old ) LOAEL = 10

mg/kg/day **Acute RfD = 0.1 m**  **g/kg/day aPAD = 0.1**  **mg/kg/day** UF A = 10x UF H = 10x FQPA SF = 1x **Prenatal Developm**  **ental Toxicity -**  **Rats**

Developmental LOAEL = 1 0 0 m g/kg/day based on clinical signs, decreased body weight and food consumption during the dosing period.

Chronic Dietary; (all populations) NOAEL = 1.0 mg/kg/day **Co -**  **critical Study** NOAEL = 1.5 mg/kg/day **Chronic RfD = 0.01 m**  **g/kg/day cPAD = 0.01**  **mg/kg/day** UF A = 10x UF H = 10x FQPA SF = 1x cPAD = 0.01 mg/kg/day **Chronic Toxicity -**  **Dogs**

LOAEL = 8.9/10.4 mg/kg/day [M/F] based on changes in hematological and clinical chemistry parameters, and histopathology in bone marrow , liver, and kidney in the one

- ye ar dog feeding study. **Mouse Carcinogenicity Study** NOAEL = 1.5 (M) LOAEL = 15.4 (M) mg/kg/day based on hematology parameters and possibly kidney weights

. Cancer Bifenazate is classified as "not likely" to be a human carcinogen. 1 UF = uncert ainty factor ; UF A = extrapolation from animal to human (interspecies); UF H = potential variation in sensitivity among members of the human population (intraspecies) , FQPA SF = FQPA safety factor, NOAEL = no

observed adverse effect

- level, LOAEL = lowest

- observed adverse

- effect level, aPAD = acute population

- adjusted dose , cPAD = chronic population

- adjusted dose, RfD = reference

- dose. 

### V **II . Results/Discussion**  Acute Dietary

Exposure AssessmentBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

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### The acute anal ys is for the g eneral p opulation, including infants and children was unrefined and used tolerance

- level residues and 100 % CT . The acute anal ys is for females 13 to 49 y ears old was highl y refined and incorporated data from the USDA’s PDP, crop field trial data, and PCT e stimates

. DEEM (ver. 7.81) default processing factors were assumed for all commodities excluding apple juice, grape juice, wine/sherry . The processing factors for these commodities were reduced to 1.0, based on data from processing studies. The anal ys es also included the acute surface water point estimate generated using FIRST and the dry bean application scenario (2 x 0.75 lb ai/acre; 14

- day

RTI; highest registered/proposed rate). The acute risk estimate utilizes <1% (0.0 40436 mg/kg/day ) of the aPAD fo r the U.S. population at the 95 th 

### percentile of exposure. The most highly

- exposed population subgroup was children 1 to 2 y ears old which utilized 1. 9 % (0. 113582 mg/kg/day ) of the aPAD at the 95 th 

### percentile of exposure. The acute risk estimate utilizes 9.9 % (0.0099 41 mg/kg/day ) of the aPAD for females 13 to 49 y ears old at the 99 .9 th 

### percentile of exposure. Thus, acute dietary exposure to bifenazate for all population subgroups is not of concern. Detailed results of the anal ys es are shown in Tables 4 and 5 , below. The output files for th ese assessment s are included as Attachment s 5 and 8. Chronic Dietary

Exposure Assessment The chronic dietary

exposure anal ys is for the all population subgroups was partially refined and used tolerance

- level residues and PCT estimates . DEEM (ver. 7.81) default processing factors were assumed for all commodities excluding apple juice, grape juice, and wine/sherry . The processing factors for these commodities were reduced to 1.0, based on data from processing studies. The anal ys es also included the chronic surface water point estimate generated using the F IRST and the dry bean application scenario (2 x 0.75 lb ai/acre; 14

- day RTI; highest registered/proposed rate). The chronic risk estimate utilizes 2 4 % (0.002 360 mg/ kg/day ) of the cPAD for the U.S. population. The most highl y - exposed population subgroup was children 1 to 2 y ears old which utilized 7 4 % (0.0074 38 mg/kg/day ) of the cPAD. Thus, chronic dietary exposure to bifenazate for all population subgroups is not o f concern. Detailed results of the anal ys es are shown in Table 6 , below. The output files for this assessment are included as Attachment 10.
**Table 4**  **. Results of the Bifenazate Acute Dietary (Food and Water)**  **Exposure Analysis for the General**

**Population (Including Infants and Children**  **) .**  **Population Subgroup aPAD**  **(m g/kg/day)**  **95 th**  **Percentile 99**  **th Percentile**  **99.9 th**  **Percentile**

**Exposure (m**  **g/kg/day) %** 

**aPAD Exposure**  **(m g/kg/day)**  **%**

**aPAD Exposure**  **(m g/kg/day)**  **%**

**aPAD** General U.S. Population 6 0.040436 <1 .0 0.083966 1 .4 0.163136 2.7 All Infants (<1 y ear old) 6 0.079571 1

. 3 0.124819 2.1 0.230245 3.8 **Children 1 to 2 years old 6**  **0.113582 1.**  **9 0.183430**  **3 .**  **1 0.262565**  **4.4** Children 3 to 5 years old 6 0.098092 1. 6 0.154745 2.6 0.275817 4.6 Children 6 to 12 years old 6 0.055662 <1 .0 0.098787 1

. 6 0.160533 2.7 Youth 13 to 19 years old 6 0.031028 <1 .0 0.058448 <1 .0 0.105872 1. 8 Ad ults 20 to 49 years old 6 0.031220 <1 .0 0.054219 <1 .0 0.090788 1 .5 Ad ults 50 to 99 years old 6 0.028073 <1 .0 0.048569 <1 .0 0.084429 1 .4 *T he values for the highest exposed population for each type of risk assessment are bolded.
**Table 5**  **. Results of the Bifenazate Acute Dietary (Food and Water)**  **Exposure Analysis for Fem ales 13 to 49** 

**Years Old.**  **Population Subgroup aPAD**  **(m g/kg/day)**  **95 th**  **Percentile 99**  **th Percentile**  **99.9 th**  **Percentile**

**Exposure (m**  **g/kg/day) %** 

**aPAD Exposure**  **(m g/kg/day)**  **%**

**aPAD Exposure**  **(m g/kg/day)**  **%**

**aPAD** Fem ales 13 to 49 years old 0.1 0.002 774 2

. 8 0.00 4 394 4

. 4 0.009 9 41 9.9Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 8 of 53 **Table 6**  **. Summary of Chronic Dietary Exposure and Risk for Bifenazate (Drinking Water Exposure Included).**  **Population Subgroup cPAD (m**  **g/kg/day) Chronic**  **Exposure (mg/kg/day) %cPAD**  General U.S. Population 0.01 0.002 360 2 4 All Infants (<1 year old) 0.00 3713 3 7 **Children 1 -**  **2 years old 0.007**  **438 7**  **4** Children 3

- 5 y ears old 0.00 5635 56 Children 6

- 12 y ears old 0.00 3053 31 Youth 13

- 19 y ears old 0.00 1858 19 Ad ults 20

- 49 y ears old 0.00 2106 21 Ad ults 50

- 99 years old 0.00 1681 1 7 Fem ales 13

- 49 y ears old 0.00 1950 20 *T he values for the highest exposed population for each type of risk assessment are bolded. 

### VI **I I**  **. Characterization**  **of Inputs/Outputs** The acute dietary

exposure assessment for the g eneral p opulation (including infants and children) were not refined and utilized tolerance

- level residues and 100 % CT . The acute anal ys is for f emales 13 to 49 y ears old was highl y refined and utilized PDP data, crop field trial data, and PCT estimates. For the highl y refined acute anal ys is , the risk drivers are water, direct, all sources, mango and mango juice, followed b y hop, passionfruit juice, and eggplant. This anal ys is can be refined further with the use of experimentally determined concentration factors and refining the exposure due to water. The chronic dietary

assessment for all populatio n subgroups was partiall y refined and utilized tolerance

- level residues and PCT estimates. This anal ys is can be refined further with the use of anticipated residue estimates, PDP data, experimentally determined concentration factors, and refining the expo sure due to water. **I X**  **. Conclusions** The acute risk estimate utilizes <1% (0.0 40436 mg/kg/day ) of the aPAD for the U.S. population at the 95 th 

### percentile of exposure. The most highl y - exposed population subgroup was children 1 to 2 ye ars old which utilize d 1. 9 % (0. 113582 mg/kg/day ) of the aPAD at the 95 th 

### percentile of exposure. The acute risk estimate utilizes 9.9 % (0. 0099 41 mg/kg/day ) of the aPAD for females 13 to 49 y ears old at the 99 .9 th 

### percentile of exposure. Thus, acute dietary exposure to bifena zate for all population subgroups is not of concern. The chronic risk estimate utilizes 2 4 % (0.002 360 mg/kg/day ) of the cPAD for the U.S. population. The most highl y - exposed population subgroup was children 1 to 2 y ears old which utilized 7 4 % (0.00 7438 mg/kg/day ) of the cPAD. Thus, chronic dietary exposure to bifenazate for all population subgroups is not of concern. **X . List of Attachments**  Attachment 1. Data and Residue Estimates Used in the Dietary Exposure Analy ses . Attachment 2. Bifenazate An ticipated Residues Estimates. Attachment 3. BEAD Percent Crop Treated Data. Attachment 4. Bifenazate Acute Residue Input File for General Population

. Attachment 5. Bifenazate Acute Residue Results for General Population.Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

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### Attachment 6. Bifenazate Acute Residue Input File for Females 13 to 49 Years Old. Attachment 7. Bifenazate Acute RDFs. Attachment 8

. Bifenazate Acute Results for Females 13 to 49 Years Old Attachment 9. Bifenazate Chronic Residue Input File. Attachment 10. Bifenazate Chronic Results.

RDI: DE SAC Reviewers : 8/15 /201 3Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

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### Attachment 1. Data and Residue Estimates Used in the Dietary Exposure Analyses. **Table 1. Bifenazate Residue Data**  **Summary Table. Comm**  **odity DEEM**  **Food Form Tolerance** 

**ppm Data Source**  **Anticipated Residue (ppm) or RDF #**  **Blended**

**Classification % CT**  **Acute Chronic**  **1 Max**  **Avg Tuberous and Corm Vegetables (Crop Subgroup 1C)**  Arrow root, F lour Jerusalem Artichoke Cassava Corm Dasheen Ginger Corm Tanier Turmeric All 0.10 Tolerance Level 0.10 0.10 PB 100 100

Potato, Chips Potato, Dry (Granules and Flakes) Potato, Flour All , Except Frozen Form s 0.10 PDP Data 0.001 0.10 B 5 5 Potato, Chips Potato, Dry (Granules and Flakes) Potato, Flour Frozen Forms 0.10 PDP Data 0.0005 0.10 B 5 5

Potato, T uber All , Except Frozen Form s 0.10 PDP Data/ Tolerance Level RDF 17 0.10 PB/NB 5 5 Potato, T uber Frozen Forms 0.10 PDP Data/ Tolerance Level RDF 18 0.10 PB/NB 5 5 Sweet Potato Yam Bean, True Yam All , Except Babyfood 0.10 PDP Data/ Tolerance Level RDF 23 0.10 PB/NB 100 100 **Comments Concerning Sweet Potato, Yam Bean, and True Yam**  **:** As per 40 CFR 180.1(g) tolerances for residues on sw eet potatoes also apply to yam. Thus, the RDF files for sweet potato w ere used for yam bean and true yam. Sweet Potato Babyfood 0.10 PDP Data/ Tolerance Level RDF 24 0.10 PB/NB 100 100 **Tropical Fruit** Acerola Feijoa Passionfruit Starfruit All 0.90 Tolerance Level 0.90 0.90 NB 100 100 Atemoya Cherimoya Soursop All 1.6 Tolerance Level 1.6 1.6 NB 100 100 Canistel Mam ey A pple Mam ey Sapote All 7.0 Tolerance Level 7.0 7.0 NB 100 100 Mango Avocado All, E xcept D ried 7.0 Field Trial Data RDF 3 3 7.0 NB 100 100 Mango, Dried Papaya, Dried All 7.0 Tolerance Level 7.0 7.0 B 100 100 Lo n gan Spanish Lime All 5.0 Tolerance Level 5.0 5.0 NB 100 100 Guava All 0.90 Field Trial Data RDF 30 0.90 NB/PB 100 100 Sugar Apple All 1.6 Tolerance Level 1.6 1.6 NB 100 100 Papaya All 7.0 Field Trial Data RDF 33 7.0 NB 100 100 Lychee All 5.0 Field Trial Data RDF 32 5.0 NB 100 100 Lychee, Dried All 5.0 Tolerance Level 5.0 5.0 B 100 100Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 11 of 53 **Table 1. Bifenazate Residue Data**  **Summary Table. Comm**  **odity DEEM**  **Food Form Tolerance** 

**ppm Data Source**  **Anticipated Residue (ppm) or RDF #**  **Blended**

**Classification % CT**  **Acute Chronic**  **1 Max**  **Avg Legume Vegetables, edible**  **- podded (Crop Subgroup 6A**  ) Bean, Snap, Succulent Bean, Cow

pea, Succulent Bean, Lima, Succulent All except Babyfood 6.0 PDP Data/ Tolerance Level RDF 5 6.0 PB 2.5 100, (1.0 for snap beans) Bean, Snap, Succulent Babyfood 6.0 PDP Data/ Tolerance Level RDF 6 6.0 PB 2.5 1.0 Pea, Edible Podded, Succulent All except Baby food 6.0 PDP Data/ Tolerance Level RDF 5 6.0 PB 2.5 100 Pea, Edible Podded, Succulent Babyfood 6.0 PDP Data/ Tolerance Level RDF 6 6.0 PB 2.5 100 **Pea and Bean, Succulent Shelled (Crop Subgroup 6B)** Bean, Broad, Succulent Bean Cow

pea, Succulent Bean, Lima, Succulent Pea, Succulent Pea, Pigeon, Succulent All Except Babyfood 0.70 PDP Data/ Tolerance Level RDF 5 0.70 PB 2.5 100
Pea, Succulent Babyfood 0.70 PDP Data/ Tolerance Level RDF 6 0.70 PB 2.5 100 Soy bean, Seed Seed only 0.70 Tolerance Level 0.70 0.70 B 100 100 **Comments Concerning Succulent beans and Peas:** As per 40 CFR 180.1(g) tolerances for residues on succulent bean are applied to all succulent beans. Thus, the RDF files for green beans were used for all other succulent beans. The RDF files for green beans were also applied to succulent peas. **Bean, Dry Seed** Bean, Great Northern, Seed Bean, Black, Seed Bean, Broad, Seed Bean, Cow

pea, Seed Bean, Kidney, Seed Bean, Lima, Seed Bean, Mung, Seed Bean, Navy, Seed Bean, Pink, Seed Bean, Pinto, Seed Chickpea, All Forms Guar, Seed, All Forms Lentil, Seed Pea, Dry, All Forms Pea, Pigeon All 0.60 Tolerance Level 0.60 0.60 B 100 100

**Vegetables, Fruiting, (Crop Group 8)** Eggplant Okra Goji Berry All 4 .0 Tolerance Level 4 .0 4 .0 NB/PB 100 100 Pepper, Bell and Nonbell All Except Dried 4 .0 PDP Data/ Tolerance Level RDF 16 4 .0 NB/PB 10 5 Pepper, Bell and Nonbell Dried 4 .0 PDP Data 0.0008 4 .0 B 10 5 Tom ato, Paste Tom ato, Puree Tom ato, Dried All 4 .0 Field Trial Data/Tolerance Level 0.11

(Mean Field Trial) 4 .0 B 10 5Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 12 of 53 **Table 1. Bifenazate Residue Data**  **Summary Table. Comm**  **odity DEEM**  **Food Form Tolerance** 

**ppm Data Source**  **Anticipated Residue (ppm) or RDF #**  **Blended**

**Classification % CT**  **Acute Chronic**  **1 Max**  **Avg** Tom atillo Tom ato Tom ato, Juice Tom ato, Tree All 4 .0 Field Trial Data Tolerance Level RDF 28 4 .0 PB 10 5 **Comments Concerning Tomato and Tom atillo:**  Em pirical processing factors of 1.2x for tomato paste and 5.0x for tomato puree were utilized (MRID 45772006). As per 40 CFR 180.1(g) tolerances for residues on tomato also apply to tomatillo. Data for tomato were translated to tomatillo. **Vegetable, Cucurbits (Crop Group 9)**  Chayote, Fruit Chinese Waxgourd Pum pkin All 0.75 Tolerance Level 0.75 0.75 NB 100 5.0 for pum pki ns 100 2.5 for pum pki ns Cantaloupe Honeydew Melon All 0.75 PDP Data/ Tolerance Level RDF 8 0.75 PB/NB 2.5 1.0 **Comments Concerning Cantaloupe and Honeydew Melon:**  Cantaloupe and honeydew melon are closely related muskmelons. The RDF file for cantaloupe was used for honeydew melon. Cucumber All 0.75 PDP Data/ Tolerance Level RDF 10 0.75 NB/PB 5.0 2.5 Squash, Summer Balsam Pear Chayote Fruit Chinese W axgourd All 0.75 PDP Data/ Tolerance Level RD F 20 0.75 NB/PB 2.5 1.0 **Comments Concerning Summer Squash ,**  **Balsam Pear**  **, Chayote Fruit, and Chinese Waxgourd :**  As per 40 CFR 180.1(g) tolerances for residues on summer squash also apply to balsam pear , chayote fruit, and Chinese waxgourd

. The RDF file for summer squash were used for balsam pear , chayote fruit, and Chinese w axgourd

. Squash, Winter All 0.75 PDP D ata/ Tolerance Level RDF 21 0.75 NB/PB 2.5 1.0 Watermelon All 0.75 PDP Data/ Tolerance Level RDF 26 0.75 NB/PB 2.5 1.0 **Fruit, Pom e (Crop Group 11)**  Apple All Except Apple Sauce , Juice , and Dried 0.75 PDP Data/ Tolerance Level RDF 2 0.75 NB/PB 5 5 Apple, Sauce Apple, Sauce

- Baby food All 0.75 PDP Data/ Tolerance Level RDF 4 0.75 PB 5 5 Apple, Juice All 0.75 PDP Data/ Tolerance Level RDF 3 0.75 PB 5 5 Apple, Dried All 0.75 PDP Data 0.0003 0.75 Blended 5 5 Crabapple Loquat Quince All 0.75 Tolerance Level 0.75 0.75 NB 100 100
Pear All 0.75 PDP Data/ Tolerance Level RDF 15 0.75 NB/PB 30 15 **Fruit, Stone (Crop Group 12)** Cherry All 2.5 PDP Data/ Tolerance Level RDF 9 2.5 PB 5 2.5 Nectarine Peach All 2.5 PDP Data/ Tolerance Level RDF 14 2.5 NB/PB 10 5 **Comments Concerning Nectarine and Peach:** As per 40 CFR 180.1(g) tolerances for residues on peach also apply to nectarine. The RDF file for peach was used for nectarine. Apricot All 2.5 PDP Data/ Tolerance Level RDF 27 2.5 NB/PB 10 5Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 13 of 53 **Table 1. Bifenazate Residue Data**  **Summary Table. Comm**  **odity DEEM**  **Food Form Tolerance** 

**ppm Data Source**  **Anticipated Residue (ppm) or RDF #**  **Blended**

**Classification % CT**  **Acute Chronic**  **1 Max**  **Avg** Plum All 0.20 PDP Data/ Tolerance Level RDF 29 0.20 NB/PB 20 5 **Caneberry (Crop Subgroup 13 -**  **07A)** Blackberry Boy senberry Loganberry Raspberry All 5.0 Field Trial Data RDF 35 5.0 PB 30 25 **Comments Concerning Blackberry, Boysenberry, Loganberry, and Raspberry:** As per 40 CFR 180.1(g), blackberry, boysenberry, loganberry, and raspberry are closely related and defined as caneberries. The RDF file contains field trial dat a for blackberries and raspberries. The RDF file for caneberries was used for blackberry, bo ys enberry, loganberry, and raspberry. **Sm all Fruit Vine Climbing Except Kiwifruit (Crop Subgroup 13**  **- 07F)**  Grape All Except Juice 0.75 PDP Data/ Tolerance Level RDF 11 0.75 PB 20 10 Grape Juice Grape, Juice

– Baby food Grape w ine and Sherry All 0.75 PDP Data/ Tolerance Level RDF 12 0.75 PB 20 10 Grape, leaves All 0.75 Tolerance Level 0.75 0.75 PB 20 10 **Berry, low -**  **growing (Crop Subgroup 13 -**  **07G)** Cranberry Straw berry All 1.5 PDP Data/ Tolerance Level RDF 22 1.5 PB 65 45 **Comments Concerning Cranberry and Strawberry:**  Straw berry is the representative commodity for Crop Subgroup 13

- 07F. Cranberry is a member of this subgroup. The RDF file for straw berry w as used for cranberry. The percent crop treated (PCT) estimates for cranberry were low er than the PCT estimates for straw berry ; therefore, the PCT estimates for straw berry w ere used in the RDF file since it was larger. **Tree Nuts (Crop Group 14)** Almond All 0.20 PDP Data/ Tolerance Level RDF 1 0.20 PB 10 5 Almond oil All 0.20 PDP Data/ Tolerance Level 0.0005 0.20 B 10 5 Brazil Nut Butternut Cashew Chestnut Hazel Nut Hickory Nut Macadamia Nut Pistachio Pine Nut All 0.20 Tolerance Level 0.20 0.20 PB 100 100

Hazel Nut Oil All 0.20 PDP Data/ Tolerance Level 0.0005

(from Almond PDP Data) 0.20 B 100 100

Pecan All 0.20 PDP Data RDF 19 0.20 PB 10 10 Walnut All 0.20 PDP Data RDF 25 0.20 PB 5 10Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 14 of 53 **Table 1. Bifenazate Residue Data**  **Summary Table. Comm**  **odity DEEM**  **Food Form Tolerance** 

**ppm Data Source**  **Anticipated Residue (ppm) or RDF #**  **Blended**

**Classification % CT**  **Acute Chronic**  **1 Max**  **Avg Herb Subgroup 19A, Fresh and Dried Leaves**  Basil, Fresh Leaves Cilantro, Leaves Cilantro, Leaves

- Babyfood Dillweed Herbs, Other Herbs, Other

- Babyfood Lemongrass All 30 Tolerance Level 30 30 B 100 100

Basil, Dried Leaves All 300 Tolerance Level 300 300 B 100 100 **Other Commodities** Peppermint Spearmint All 25 Tolerance Level 25 25 B 100 100 Cottonseed, oil All 0.75 Tolerance Level 0.75 0.75 B 100 100 Hops All 15 Tolerance Level 15 15 B 100 100 Cattle, Goats, Hogs, Horse, and Sheep: Meat Meat Byproducts All 0.02 Tolerance Level 0.02 0.02 B/PB/NB 100 100 Cattle, Goats, Hogs, Horse, and Sheep: Fat All 0.10 Tolerance Level 0.10 0.10 B/PB/NB 100 100 Milk All 0.02 Tolerance Level 0.02 0.02 B 100 100 Peppermint Peppermint Oil All 25 Tolerance Level 25 25 B 100 100 Spearmint Spearmint Oil All 25 Tolerance Level 25 25 B 100 100

1 The chronic values were also used for the acute analysis for the general population (including infants and children).Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 15 of 53 

### Attachment 2. Bifenazate Anticipated Residues Estimates **.** The limit of quantitation (LOQ) for bifenazate and its metabolite D3598 was generall y 0.01 ppm in most field trial studies. **Tuberous and Corm Vegetables (Crop Subgroup 1C)**  Tolerance

- level residues were assumed for arrowroot flour, Jerusalem artichoke, cassava, corm dasheen, ginger, corm tanier, and turmeric. Potato: Source of residue data: PDP Data from 2009 and 2008. **Potato, Tuber**  **(except frozen forms)** Blended Classification: PB/NB Acute AR

– **RDF 17** Max percent treated = 5% 4 26 Total Samples 4 26 x 0.05 = 21 treated samples 1⁄2 L OD = 0.02 ppm **Potato, chips, dry (granules and flakes), flour (except frozen forms)**  Blended Classification: B Acute AR

– Point Estimate Max percent treated = 5% 426 Total Samples 426 x 0.05 = 21 treated samples 1⁄2 L OD = 0.02 ppm 21 x 0.02/426 = 0.001 ppm Source of residue data: PDP Data from 2008. **Potato, Tuber (**  **frozen forms )**  Blended Classification: PB/NB Acute AR

– **RDF 18** Max percent treated = 5% 11 63 Total Samples 11 63 x 0.05 = 58 treated samples 1⁄2 L OD = 0.01 ppm **Potato, chips, dry (granules and flakes), flour (frozen forms)** Blended Classification: B Acute AR

– Point Estimate Ma x percent treated = 5% 1163 Total Samples 1163 x 0.05 = 58 treated samples 1⁄2 L OD = 0.02 ppm 58 x 0.01/1163 = 0.0005 ppmBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 16 of 53 

### Source of residue data: 2009 and 2010 PDP Data. **Sweet Potato, All Forms (except Baby Food)** Blended Classification: PB/NB Acute AR

– **RDF 23** Max percent treated = 5% (value for potato) 763 Total Samples 763 x 0.05 = 38 treated samples 1⁄2 L OD = 0.02 ppm As per 40 CFR 180.1(g) tolerances for residues on sweet potatoes also appl y to y am. This RDF was translated to true yam and y am bean. Thus, RDF 23 was used for these commodities. Source of residue data: 2009 and 2010 PDP Data. **Sweet Potato, Baby Foo d**  Blended Classification: PB/NB Acute AR

– **RDF 24** Max percent treated = 5% (value for potato) 191 Total Samples 191 x 0.05 = 10 treated samples 1⁄2 L OD = 0.015 ppm **Edible -**  **podded Legume Vegetables Subgroup (Crop Subgroup 6A) and Succulent Shelled Pea and**  **Bean Subgroup (Crop Subgroup 6B). Snap Beans (Green Beans in PDP):**  Source of residue data: 2008 PDP Data. **Snap Beans, All Forms (except babyfood)** Blended Classification: PB Acute AR

– **RDF 5** Max percent treated = 2.5% 215 Total Samples 215 x 0.025 = 5 treated samples 1⁄2 L OD = 0.01 ppm These data were also used for succulent edible podded pea, succulent cowpea bean, succulent lima bean, succulent pigeon pea, and succulent pea. Source of Data: 2010 PDP Data. **Snap Beans, babyfood** Blended Classification: PB Acute AR

– **RDF 6** Max percent treated = 2.5% 192 Total Samples 192 x 0.025 = 5 treated samples 1⁄2 L OD = 0.0015 ppmBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 17 of 53 

### The snap bean, bab yfood data were used for succulent pea, bab yfood. **Fruiting Vegetables (Except Cucurbits) (Crop Group 8)**  Tolerance

- level residues were assumed for eggplant , goji berry , and okra. **Bell and Nonbell Peppers:** Source of Data: 2010 PDP Data **Bell Pepper, All Forms (except dried)**  Blended Classification: PB Acute AR

– **RDF 16** Max percent treated = 10% 744 Total Samples 744 x 0.10 = 74 treated samples 1⁄2 L OD = 0.0085 ppm **Bell Pepper, Dried Forms** Blended Classification: B Acute AR

– Point Estimate Max percent treated = 10% 744 Total Samples 744 x 0.10 = 74 treated samples 1⁄2 L OD = 0.0085 ppm 74 x 0.0085/744 = 0.0008 ppm **Tomato:** Source of Data: MRID 45772006 (For Both Acute And Chronic Anal ys is). An RFD file (RDF 28) was constructed using the residue data from MRID 45772006. As per 40 CFR 180.1(g) tolerances for residues on tomato also apply to tomatillo. This RDF was translated to tomatillo.
**Residue Data from Tom**  **ato Field Trials Study Location; Year; and**  **USEPA Region Crop**  **Variety Comm**  **odity Total**  **Rate, lb ai/acre**  **PHI**

**(days) Bifenazate and** 

**D3598 (ppm )**  **1** Gainsville, FL; 2000; Region 3 FL47 Fruit 0.50 3 0.185 Gainsville, FL; 2000; Region 3 Celebrity Fruit 0.50 3 0.14 El Centro, CA; 2000; Region 10 Rio Grande Fruit 0.48 3 0.065 El Centro; CA; 2000; Region 10 Yaqui Fruit 0.48 3 0.035 Five Points, CA; 2000; Region 10 H9553 Fruit 0.52 3 0.095 Parlier, CA; 2000; Region 10 Celebrity Fruit 0.52 3 0.035 Parlier, CA; 2000; Region 10 Shady Lady Fruit 0.52 3 0.04 Visalia, CA; 2000; Region 10 3135 VF Fruit 0.49 3 0.135 Bridgeton, NJ; 2000; Region 2 FT 4010 Fruit 0.51 3 0.05 Cambridge, ON; 2000; Region 5B 9478 Fruit 0.46 3 0.345 1 D3598 and bifenazate are quantified together; method does not distinguish between these compounds.Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 18 of 53 

### For tomato paste, tomato puree, and dried tomato, the mean field trial value was used in the acute assessment as these commodities are classified as blended. **Summary of Tom ato Crop Field Trials**  **Comm odity**  **Total Applic.**

**Rate, lb ai/acre PHI** 

**(days) Analyte**  **Residue Levels (ppm) Min.**  **Max. HAFT**  **1 Me**  **an Std. Dev.**  tom ato fruit (n=9) 0.46

- 0.52 2

- 3 bifenazate and D3598 0.02 0.45 0.34 0.11 0.09 tom ato fruit (n=1) 0.18 3 0.03 0.03

-- -- -- 1 HAFT = highest

- average field trial

. 

### Cucurbit Vegetables (Crop Group 9) Tolerance

- level residues were assumed for balsam pear, chay ote fruit, Chinese waxgourd, and pumpkin. **Cantaloupe (and Honeydew melon):** Source of Data: 2004 and 2005 PDP Data. **Cantaloupe, All Forms (and Honeydew Melon, All Forms)**  Blended Classification: NB Acute AR

– **RDF 8** Max percent treated = 2.5% 483 Total Samples 483 x 0.025 = 12 treated samples 1⁄2 L OD = 0.007 ppm **Cucumber:** Source of Data: 200 9 and 20 10 PDP Data. **Cucumber, All Forms** Blended Classification: NB Acute AR

– **RDF 10** Max percent treated = 5% 582 (1 detect) Total Samples 582 x 0.05 = 29 (

- 1 detect) treated samples 1⁄2 L OD = 0.02 ppm **Summer Squash:** Source of Data: 2006, 2007, and 200 8 PDP Data. **Summer Squash, all forms** Blended Classification: NB Acute AR

– **RDF 20** Max percent treated = 2.5% 426 Total Samples 426 x 0.025 = 11 treated samples 1⁄2 L OD = 0.01 ppmBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 19 of 53 

### Winter **Squash:** Source of Data: 2004, 2005, and 2006 PDP Data. **Winter Squash, all forms** Blended Classification: NB Acute AR

– **RDF 21** Max percent treated = 2.5% 1332 Total Samples 1332 x 0.025 = 33 treated samples 1⁄2 L OD = 0.017 ppm **Watermelon:** Source of Da ta: 2009 and 2010 PDP Data. **Watermelon, all forms** Blended Classification: NB Acute AR

– **RDF 26** Max percent treated = 2.5% 371 Total Samples 371 x 0.025 = 9 treated samples 1⁄2 L OD = 0.017 ppm **Po me Fruit (Crop Group 11)**  Tolerance

- level residues were assumed for crabapple, loquat, and quince. **Apple:** Source of Data: 2009 PDP Data (Fruit and Dried Forms). Source of Data: 200 7

- 2008 PDP Data (Juice). Source of Data: 2006 PDP Data (Sauce). **Apple, Fruit, (all forms except juice and sauce)** Blended Classification: NB Acute AR

– **RDF 2** Max percent treated = 5% 641 Total Samples 641 x 0.05 = 32 treated samples 1⁄2 L OD = 0.021 ppm **Apple, Juice** Blended Classification: PB Acute AR

– **RDF 3** Max percent treated = 5% 2 1 4 Total Samples 2 14 x 0.05 = 1 1 treated samples 1⁄2 L OD = 0.01 ppm **Apple, Sauce** Blended Classification: PBBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 20 of 53 

### Acute AR

– **RDF 4** Max percent treated = 5% 216 Total Samples 216 x 0.05 = 11 treated samples 1⁄2 L OD = 0.01 ppm **Apple, Dried** Blended Classification: B Acute AR

– Point Estimate Max percent treated = 5% 641 Total Samples 641 x 0.05 = 32 treated samples 1⁄2 L OD = 0.021 ppm 32 x 0.021/641 = 0.001 ppm **Pear:** Source of Data: 2004 and 2005 PDP Data. **Pear, All Forms** Blended Classification: NB Acute AR

– **RDF 15** Max percent treated = 30% 377 (4 detects) Total Samples 377 x 0.30 = 113 (

- 4 detects) = 109 T reated S amples 1⁄2 L OD = 0.01 ppm **Stone Fruit (Crop Group 12)** Tolerance

- level residues were assumed for nectarine. **Cherry:** Source of Data: 2007 PDP Data. **Cherry, All Forms**  Blended Classification: PB Acute AR

– **RDF 9** Max percent treated = 5% 1 22 Total Samples 1 22 x 0.05 = 6 treated samples 1⁄2 L OD = 0.01 ppm **Peach :** Source of Data: 2007 and 2008 PDP Data. **Peach, All Forms** Blended Classification: NB/PB Acute AR

– **RDF 14** Max percent treated = 20% 1006 (1 1 detects) Total Samples 1006 x 0.20 = 201 (

- 1 1 detects) = 1 90 T reated S amplesBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 21 of 53 

### 1⁄2 L OD = 0.015 ppm Plum: ( **RFD 29** ) Source of Data: Crop Field Trial Data (MRID 45052326 and 406064102)
**Residues of Bifenazate/D3598 in/on Plums.**  **Trial Site Treatm**  **ent Rate**  **(lb ai/acre) PHI** 

**(days) Combined Residues** 

**Bifenazate/D3598 1**  **(ppm )**  Plums Conklin, MI (Region 5) 0.50 3 0.125 Madera, CA (Region 10) 0.51 3 0.01 Ivanhoe, CA (Region 10) 0.50 3 0.035 Davis, CA (Region 10) 0.50 3 0.060 Mary sville, CA (Region 10) 0.50 3 0.035 Dallas, OR (Region 12) 0.50 3 0.03 Toppenish, WA (Region 11) 0.51 3 0.035 Residue levels are expressed as bifenazate. 

### Apricot: Source of Data: 2007 and 2008 PDP Data. **Apricot, All Forms**  Blended Classification: NB/PB Acute AR

– **RDF 27** Max percent treated = 10% 987 Total Samples 9 87 x 0.10 = 9 9 (

- 11 detects) = 88 Treated Samples 1⁄2 L OD = 0.015 ppm **Caneberry Subgroup (Crop Subgroup 13 -**  **07A) Blueberry:**  Source of Data: 2008 PDP Data (Used PDP Data for Blueberry ). **Blueberry, All Forms** Blended Classification: PB Acute AR

– **RDF 7** Max percent treated = 30% (value for caneberry ). 211 Total Samples 211 x 0.30 = 63 Treated Samples 1⁄2 L OD = 0.03 ppmBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 22 of 53 

### This RDF File was not used in the anal ys is as bifenazate is currentl y not registered for use on blueberries. **Low Growing Berry Subgroup (Crop Subgroup 13 -**  **07G) Strawberry:**  Source of Data: 2008 and 2009 PDP Data. **Strawberry, All Forms** Blended Classification: PB Acute AR

– **RDF 22** Max percent treated = 65% 1441 (1 60 detects) Total Samples 1441 x 0.65 = 937 (

- 1 60 detects) = 777 Treated Samples 1⁄2 L OD = 0.033 ppm **Grape:** Source of Data: 200 9 and 2010 PDP Data. **Grape** Blended Classification: PB Acute AR

– **RDF 11** Max percent treated = 20% 1489 (2 0 detects) Total Samples 1 489 x 0.20 = 2 9 8 (

- 2 0 detects) = 2 7 8 Treated Samples 1⁄2 L OD = 0.021 ppm **Grape Juice:** Source of Data: 2008 PDP Data. **Grape Juice** Blended Classification: PB Acute AR

– **RDF 12** Max percent treated = 20% 214 Total Samples 214 x 0.20 = 43 Treated Samples 1⁄2 L OD = 0.01 ppm **Raisins:** Source of Data: 2006 and 2007 PDP Data. **Raisins** Blended Classification: PB Acute AR

– **RDF 13**  Max percent treated = 20% 216 Total Samples 216 x 0.20 = 43 (

- 5 detects) = 3 8 Treated Samples 1⁄2 L OD = 0.01 ppmBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 23 of 53 

### Tree Nuts (Crop Group 14) Tolerance

- level residues were assumed for Brazil nut, butternut, cashew, chestnut, hazelnut , macadamia nut, pine nut, and pistachio. **Almond:** Source of Data: 2007 and 2008 PDP Data. **Almond, All Forms**  **, Except Oil**  Blended Classification: PB Acute AR

– **RDF 1** Max percent treated = 10% 547 Total Samples 547 x 0.10 = 55 Treated Samples 1⁄2 L OD = 0.005 ppm **Almond, Oil and Hazel Nut Oil**  Blended Classification: B Acute AR

– Point Estimate Max percent treated = 10% 547 Total Samples 547 x 0.10 = 55 Treated Samples 1⁄2 L OD = 0.005 ppm 55 x 0.005/547 = 0.0005 ppm **Pecan, All Forms (**  **used data, except PCT, from Almonds)** Blended Classification: PB Acute AR

– **RDF 19** Max percent treated = 2.5% 5 47 Total Samples 5 47 x 0. 025 = 1 4 Treated Samples 1⁄2 L OD = 0.005 ppm **Walnut, All Forms (used data, except PCT, from Almonds)**  Blended Classification: PB Acute AR

– **RDF 25** Max percent treated = 5% 547 Total Samples 5 47 x 0.05 = 2 7 Treated Samples 1⁄2 L OD = 0.005 ppmBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 24 of 53 

### Tropical Fruits: Guava

– ( **RFD 30** ) Source of Data: Crop Field Trial Data (MRID 47016707)
**Residue Data from Crop Field Trials with Bifenazate.**  **Trial Identification: City, State; Year**  **(Trial No.) Zone**  **Crop; Variety Commodity**  **Total Rate (lb**  **ai/A) PHI** 

**(days) Combined** 

**Bifenazate/ D3598 Residues**  **(ppm) 1**  Homestead, FL; 2004 (04

- FL36) 13 Guava; Homestead Fruit 1.04 1 0.26 0.30 Homestead, FL; 2004 (04

- FL37) 13 Guava; Homestead Fruit 1.04 1 0.039 0.18 Homestead, FL; 2004 (04

- FL38) 13 Guava; Homestead Fruit 1.04 1 0.14 0.21 1 Residues were quantified/reported as bifenazate equivalents. 

### Lychee

– ( **RDF 32** ) Source of Data: Crop Field Trial Data (MRID 4701670 2 )
**Residue Data from Crop Field Trials with Bifenazate.** 
**Trial Identification: City,**  **State; Year (Trial ID No.)**  **Zone Crop; Variety**  **Commodity or Matrix**  **Total**

**Rate (lb ai/A)**  **PHI**

**(days) Combined** 

**Bifenazate/ D3598**  **Residues (ppm)**  **1 Corrected** 

**Combined Bifenazate/**  **D3598 Residues (ppm)**  **2** Homestead, FL; 2004 04

- FL33 13 Lychee; Mauritius Fruit 1.01 1 1.9 2.0 2.8

2.9 Homestead, FL; 2004 04

- FL34 13 Lychee; Mauritius Fruit 1.02 1 2.6 2.6 3.6

3.7 Homestead, FL; 2004 04

- FL35 13 Lychee; Mauritius Fruit 1.02 1 1.5 2.3 2.2

3.3 1 Residues were quantified/reported as bifenazate equivalents. 2 Bifenazate residues corrected for a ~ 30% decline during storage. 

### Papay a

– ( **RFD 33** ) Source of Data: Crop Field Trial Data (MRID 47016708)
**Residue Data from Crop Field Trials with Bifenazate.**  **Trial Identification: City, State; Year**  **(Trial No.) Zone**  **Crop; Variety Commodity**  **Total Rate (lb ai/A)**  **PHI**

**(days) Combined** 

**Bifenazate/ D3598 Residues**  **(ppm) 1**  Homestead, FL; 2003 (03

- FL19) 13 Papaya; Red Lady Fruit 1.02 1 0.11 0.14 Haleiwa, HI; 2003 03

- HI01 13 Papaya; Gold Fruit 1.02 1 0.62 1.89 Keaau, HI; 2003 03

- HI02 13 Papaya; Kapoho Fruit 1.04 1 0.76 0.81 1 Residues were quantified/reported as bifenazate equivalents.Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 25 of 53 

### Other Commodities: Hops

– ( **RFD 34** ) Source of Data: Crop Field Trial Data (MRID 4 8052323 )
**Residues of bifenazate/D3598 in/on the Treated Dried Hop Samples**  **. Site**  **Treatm ent Rate**  **(lbs ai/acre) PHI** 

**(days) Combined Residues** 

**bifenazate/D3598 (ppm )**  **1** Granger, WA (Region 11) 0.75 13 9.31 Harrah, WA (Region 11) 0.75 14 7.79 Mt. Angel, OR (Region 12) 0.75 14 7.10 1 Com bined bifenazate/D3598 residues expressed as bifenazate

.Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 26 of 53 

### Attachment 3. BEAD Percent Crop **- Treated Data.** Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 27 of 53 

### Attachment 4. Bifenazate Acute Residue Input File for General Population. Filename: J: \ Work Files \ $ Bifenazate \ $$New \ DEEM \ 03_25_2014_Tolerance levels_Bifenazate_Acute.R08 Chemical: Bifenazate RfD(Chronic): 0 mg/kg bw/day NOEL(Chronic): 1 mg/kg bw/day RfD(Acute): 0 mg/kg bw/day NOEL(Acute): 10 mg/kg bw/day Date created/last modified: 03

- 25

- 2014/14:34:04 Program ver. 3.16, 03

- 08

- d Comment: aPAD for General Pop

- 6 mg/kg/day; aPAD for Females 13 to 49 years

- 0.1 mg/kg/day; cPAD

- 0.01 mg/kg/day

-------------------------------------------------------------------------------- EPA Crop Def Res Adj.Fa ctors C omment Code Grp Commodity Name (ppm) #1 #2

---------- ---- ------------------------------- ---------- ------ ------ ---- 0103015000 1CD Arrowroot, flour 0.100000 1.000 1.000 010301500 1 1CD Arrowroot, flour

- babyfood 0.100000 1.000 1.000 0103017000 1CD Artichoke, Jerusalem 0.100000 1.000 1.000 0103082000 1CD Cassava 0.100000 1.000 1.000 0103082001 1CD Cassava

- babyfood 0.100000 1.000 1.000 0103139000 1CD Dasheen, corm 0.100000 1.000 1.000 0103166000 1CD Ginger 0.100000 1.000 1.000 0103166001 1CD Ginger

- babyfood 0.100000 1.000 1.000 0103167000 1CD Ginger, dried 0.100000 1.000 1.000 0103296000 1C Potato, chips 211

- Cooked; Fresh or N/S; Baked 0.100000 1.000 1.000 213

- Cooked; Fresh or N/S; Fried 0.100000 1.000 1.000 0103297000 1C Potato, dry (granules/ flakes) 211

- Co oked; Fresh or N/S; Baked 0.100000 6.500 1.000 212

- Cooked; Fresh or N/S; Boiled 0.100000 6.500 1.000 213

- C ooked; Fresh or N/S; Fried 0.100000 6.500 1.000 221

- Cooked; Frozen; Baked 0.100000 6.500 1.000 230

- Cooked; Dried; Cook Meth N/S 0.100000 6.500 1.000 232

- Cooked; Dried; Boiled 0.100000 6.500 1.000 0103297001 1C Potato, dry (granules/ flakes)

- b 0.100000 6.500 1.000 0103298000 1C Potato, flour 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.100000 6.500 1.000 120

- Uncooked; Frozen; Cook Meth N/S 0.100000 6.500 1.000 130

- Uncooked; Dried; Cook Meth N/S 0.100000 6.500 1.000 140

- Uncooked; Canned; Cook Meth N/S 0.100000 6.500 1.000 210

- Cooked; Fresh or N/S; Cook Meth N/S 0.100000 6.500 1.000 211

- Cooked; Fresh or N/S; Baked 0.100000 6.500 1.000 212

- Cooked; Fresh or N/S; Boiled 0.100000 6.500 1.000 213

- Cooked; Fresh or N/S; Fried 0.100000 6.500 1.000 214

- Cooked; Fresh or N/S; Fried/baked 0.100000 6.500 1.000 221

- Cooked; Frozen; Baked 0.100000 6.500 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 28 of 53 222

- Cooked; Frozen; Boiled 0.100000 6.500 1.000 223

- Cooked; Frozen; Fried 0.100000 6.500 1.000 230

- Cooked; Dried; Cook Meth N/S 0.100000 6.500 1.000 231

- Cooked; Dried; Baked 0.100000 6.500 1.000 232

- Cooked; Dried; Boiled 0.100000 6.500 1.000 233

- Cooked; Dried; Frie d 0.100000 6.500 1.000 240

- Cooked; Canned; Cook Meth N/S 0.100000 6.500 1.000 242

- Cooked; Canned; Boiled 0.100000 6.500 1.000 250

- Cooked; Cured etc; Cook Meth N/S 0.100000 6.500 1.000 251

- Cooked; Cured etc; Baked 0.100000 6.500 1.000 252

- Cooked; Cured etc; Boiled 0.100000 6.500 1.000 253

- Cooked; Cured etc; Fried 0.100000 6.500 1.000 0103298001 1C Potato, flour

- babyfood 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.100000 6.500 1.000 130

- Uncooked; Dried; Cook Meth N/S 0.100000 6.500 1.000 211

- Cooked; Fresh or N/S; Bak ed 0.100000 6.500 1.000 240

- Cooked; Canned; Cook Meth N/S 0.100000 6.500 1.000 0103299000 1C Potato, tuber, w/peel 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 1.000 210

- Cooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 1.000 211

- Cooked; Fresh or N/S; Baked 0.100000 1.000 1.000 212

- Cooked; Fresh or N/S; Boiled 0.100000 1.00 0 1.000 213

- Cooked; Fresh or N/S; Fried 0.100000 1.000 1.000 0103299001 1C Potato, tuber, w/peel

- babyfood 0.100000 1.000 1.000 0103300000 1C Potato, tuber, w/o peel 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 1.000 210

- Cooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 1.000 211

- Cooked; Fresh or N/S; Baked 0.100000 1.000 1.000 212

- Cooked; Fresh or N/S; Boiled 0.10000 0 1.000 1.000 213

- Cooked; Fresh or N/S; Fried 0.100000 1.000 1.000 221

- Cooked; Frozen; Baked 0.100000 1.000 1.000 223

- Cooked; Frozen; Fried 0.100000 1.000 1.000 232

- Cooked; Dried; Boiled 0.100000 1.000 1.000 233

- Cooked; Dried; Fried 0.100000 1.000 1.000 240

- Co oked; Canned; Cook Meth N/S 0.100000 1.000 1.000 242

- Cooked; Canned; Boiled 0.100000 1.000 1.000 252

- Cooked; Cured etc; Boiled 0.100000 1.000 1.000 0103300001 1C Potato, tuber, w/o peel

- babyfood 0.100000 1.000 1.000 0103366000 1CD Sweet potato 0.100000 1.000 1.000 0103366001 1CD Sweet potato

- babyfood 0.100000 1.000 1.000 0103371000 1CD Tanier , corm 0.100000 1.000 1.000 0103387000 1CD Turmeric 0.100000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 29 of 53 0103406000 1CD Yam, true 0.100000 1.000 1.000 0103407000 1CD Yam bean 0.100000 1.000 1.000 0600347000 6 Soybean, seed 0.700000 1.000 1.000 0601043000 6A Bean, snap, succulent 6.000000 1.000 1.000 0601043001 6A Bean, snap, succulent

- babyfood 6.000000 1.000 1.0 00 0601257000 6A Pea, edible podded, succulent 6.000000 1.000 1.000 0602031000 6B Bean, broad, succulent 0.700000 1.000 1.000 0602033000 6B Bean, cowpea, succulent 212

- Cooked; Fresh or N/S; Boiled 0.700000 1.000 1.000 222

- Cooked; Frozen; Boiled 0.700000 1.000 1.000 242

- Cooked; Canned; Boiled 0.700000 1.000 1.000 0602037000 6B Bean, lima, su cculent 0.700000 1.000 1.000 0602255000 6B Pea, succulent 0.700000 1.000 1.000 0602255001 6B Pea, succulent

- babyfood 0.700000 1.000 1.000 0602259000 6B Pea, pigeon, succulent 0.700000 1.000 1.000 0603030000 6C Bean, black, seed 0.600000 1.000 1.000 0603032000 6C Bean, broad, seed 0.600000 1.000 1.000 0603034000 6C Bean, cow pea, seed 0.600000 1.000 1.000 0603035000 6C Bean, great northern, seed 0.600000 1.000 1.000 0603036000 6C Bean, kidney, seed 0.600000 1.000 1.000 0603038000 6C Bean, lima, seed 0.600000 1.000 1.000 0603039000 6C Bean, mung, seed 0.600000 1.000 1.000 0603040000 6C Bean, navy, seed 0.600000 1.000 1.000 0603041000 6C Bean, pink, seed 0.600000 1.000 1.000 0603042000 6C Bean, pinto, seed 0.600000 1.000 1.000 0603098000 6C Chickpea, seed 0.600000 1.000 1.000 0603098001 6C Chickpea, seed

- babyfood 0.600000 1.000 1.000 0603099000 6C Chickpe a, flour 0.600000 1.000 1.000 0603182000 6C Guar, seed 0.600000 1.000 1.000 0603182001 6C Guar, seed

- babyfood 0.600000 1.000 1.000 0603203000 6C Lentil, seed 0.600000 1.000 1.000 0603256000 6C Pea, dry 0.600000 1.000 1.000 0603256001 6C Pea, dry

- babyfood 0.600000 1.000 1.000 0603258000 6C Pea, pigeon, seed 0.600000 1.000 1.00 0 0801374000 8A Tomatillo 4.000000 1.000 1.000 0801375000 8A Tomato 4.000000 1.000 1.000 0801375001 8A Tomato

- babyfood 4.000000 1.000 1.000 0801376000 8A Tomat o, paste 4.000000 5.400 1.000 0801376001 8A Tomato, paste

- babyfood 4.000000 5.400 1.000 0801377000 8A Tomato, puree 4.000000 3.300 1.000 0801377001 8A Tomato, puree

- babyfood 4.000000 3.300 1.000 0801378000 8A Tomato, dried 4.000000 14.300 1.000 0801378001 8A Tomato, dried

- babyfood 4.000000 14.300 1.000 0801379000 8A Tomato, j uice 4.000000 1.500 1.000 0801380000 8A Tomato, Tree 4.000000 1.000 1.000 0802148000 8BC Eggplant 4.000000 1.000 1.000 0802234000 8BC Okra 4.000000 1.000 1.000 0802270000 8B Pepper, bell 4.000000 1.000 1.000 0802270001 8B Pepper, bell

- babyfood 4.000000 1.000 1.000 0802271000 8B Pepper, bell, dried 4.000000 1.000 1.000 0802271001 8B Pepper, bell, dried

- babyfood 4.000000 1.000 1.000 0802272000 8BC Pepper, nonbell 4.000000 1.000 1.000 0802272001 8BC Pepper, nonbell

- babyfood 4.000000 1.000 1.000 0802273000 8BC Pepper, nonbell, dried 4.000000 1.000 1.000 0901075000 9A Cantaloupe 0.750000 1.000 1.000 0901187000 9A Honeydew melon 0.750000 1.000 1.000 0901399000 9A Watermelon 0.750000 1.000 1.000 0901400000 9A Watermelon, juice 0.750000 1.000 1.000 0902021000 9B Balsam pear 0.750000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 30 of 53 0902088000 9B Chayote, fruit 0.750000 1.000 1.00 0 0902102000 9B Chinese waxgourd 0.750000 1.000 1.000 0902135000 9B Cucumber 0.750000 1.000 1.000 0902308000 9B Pumpkin 0.750000 1.000 1.000 0902309000 9B Pumpk in, seed 0.750000 1.000 1.000 0902356000 9B Squash, summer 0.750000 1.000 1.000 0902356001 9B Squash, summer

- babyfood 0.750000 1.000 1.000 0902357000 9B Squash, winter 0.750000 1.000 1.000 0902357001 9B Squash, winter

- babyfood 0.750000 1.000 1.000 1100007000 11 Apple, fruit with peel 0.750000 1.000 1.000 1100008000 11 Apple, peeled fruit 0.750000 1.000 1.000 1100008001 11 Apple, peeled fruit

- babyfood 0.750000 1.000 1.000 1100009000 11 Apple, dried 0.750000 8.000 1.000 1100009001 11 Apple, dr ied

- babyfood 0.750000 8.000 1.000 1100010000 11 Apple, juice 0.750000 1.000 1.000 1100010001 11 Apple, juice

- babyfood 0.750000 1.000 1.000 1100011000 11 Apple, sauce 0.750000 1.000 1.000 1100011001 11 Apple, sauce

- babyfood 0.750000 1.000 1.000 1100129000 11 Crabapple 0.750000 1.000 1.000 1100173500 11 Goji berry 4.000000 1.000 1.000 1100210000 11 Loquat 0.750000 1.000 1.000 1100266000 11 Pear 0.750000 1.000 1.000 1100266001 11 Pear

- babyfood 0.750000 1.000 1.000 1100267000 11 Pear, d ried 0.750000 6.250 1.000 1100268000 11 Pear, juice 0.750000 1.000 1.000 1100268001 11 Pear, juice

- babyfood 0.750000 1.000 1.000 1100310000 11 Quince 0.750000 1.000 1.000 1201090000 12A Cherry 2.500000 1.000 1.000 1201090001 12A Cherry

- babyfood 2.500000 1.000 1.000 1201091000 12A Cherry, juice 2.500000 1.500 1.00 0 1201091001 12A Cherry, juice

- babyfood 2.500000 1.500 1.000 1202012000 12B Apricot 2.500000 1.000 1.000 1202012001 12B Apricot

- babyfood 2.500000 1.000 1.000 1202013000 12B Apric ot, dried 2.500000 6.000 1.000 1202014000 12B Apricot, juice 2.500000 1.000 1.000 1202014001 12B Apricot, juice

- babyfood 2.500000 1.000 1.000 1202230000 12B Nectarine 2.500000 1.000 1.000 1202260000 12B Peach 2.500000 1.000 1.000 1202260001 12B Peach

- babyfood 2.500000 1.000 1.000 1202261000 12B Peach, dried 2.500000 7.000 1.000 1202261001 12B Peach, dried

- babyfood 2.500000 7.000 1.000 1202262000 12B Peach, juice 2.500000 1.000 1.000 1202262001 12B Peach, ju ice

- babyfood 2.500000 1.000 1.000 1203285000 12C Plum 0.200000 1.000 1.000 1203285001 12C Plum

- babyfood 0.200000 1.000 1.000 1203286000 12C Plum, prune, fresh 0.200000 1.000 1.000 1203286001 12C Plum, prune, fresh

- babyfood 0.200000 1.000 1.000 1203287000 12C Plum, prune, dried 0.200000 5.000 1.000 1203287001 12C Plum, prune, dried

- babyfood 0.200000 5.000 1.000 1203288000 12C Plum, prune, juice 0.200000 1.400 1.000 1203288001 12C Plum, prune, juice

- babyfood 0.200000 1.400 1.000 1301055000 13A Blackberry 5.000000 1.000 1.000 1301056000 13A Blackbe rry, juice 5.000000 1.000 1.000 1301056001 13A Blackberry, juice

- babyfood 5.000000 1.000 1.000 1301058000 13A Boysenberry 5.000000 1.000 1.000 1301208000 13A Loganberry 5.000000 1.000 1.000 1301320000 13A Raspberry 5.000000 1.000 1.000 1301320001 13A Raspberry

- babyfood 5.000000 1.000 1.000 1301321000 13A Raspberry, juice 5.000000 1.000 1.00 0 1301321001 13A Raspberry, juice

- babyfood 5.000000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 31 of 53 1304175000 13D Grape 0.750000 1.000 1.000 1304176000 13D Grape, juice 0.750000 1.000 1.000 1304176001 13D Grape , juice

- babyfood 0.750000 1.000 1.000 1304179000 13D Grape, wine and sherry 0.750000 1.000 1.000 1307130000 13G Cranberry 1.500000 1.000 1.000 1307130001 13G Cranberry

- babyfood 1.500000 1.000 1.000 1307131000 13G Cranberry, dried 1.500000 1.000 1.000 1307132000 13G Cranberry, juice 1.500000 1.100 1.000 1307132001 13G Cranberry , juice

- babyfood 1.500000 1.100 1.000 1307359000 13G Strawberry 1.500000 1.000 1.000 1307359001 13G Strawberry

- babyfood 1.500000 1.000 1.000 1307360000 13G Strawberry, juice 1.500000 1.000 1.000 1307360001 13G Strawberry, juice

- babyfood 1.500000 1.000 1.000 1400003000 14 Almond 0.200000 1.000 1.000 1400003001 14 Almond

- babyfood 0.200000 1.000 1.000 1400004000 14 Almond, oil 0.200000 1.000 1.000 1400004001 14 Almond, oil

- babyfood 0.200000 1.000 1.000 1400059000 14 Brazil nut 0.200000 1.000 1.000 1400068000 14 Buttern ut 0.200000 1.000 1.000 1400081000 14 Cashew 0.200000 1.000 1.000 1400092000 14 Chestnut 0.200000 1.000 1.000 1400155000 14 Hazelnut 0.200000 1.000 1.000 1400156000 14 Hazelnut, oil 0.200000 1.000 1.000 1400185000 14 Hickory nut 0.200000 1.000 1.000 1400213000 14 Macadamia nut 0.200000 1.000 1.00 0 1400269000 14 Pecan 0.200000 1.000 1.000 1400278000 14 Pine nut 0.200000 1.000 1.000 1400282000 14 Pistachio 0.200000 1.000 1.000 1400391000 14 Walnu t 0.200000 1.000 1.000 1901028000 19A Basil, fresh leaves 30.000000 1.000 1.000 1901028001 19A Basil, fresh leaves

- babyfood 30.000000 1.000 1.000 1901029000 19A Basil, dried leaves 300.000000 1.000 1.000 1901029001 19A Basil, dried leaves

- babyfood 300.000000 1.000 1.000 1901102500 19A Chive, dried leaves 300.000000 1.000 1.000 1901118000 19A Cilantro, leaves 30.000000 1.000 1.000 1901118001 19A Cilantro, leaves

- babyfood 30.000000 1.000 1.000 1901144000 19A Dillweed 30.000000 1.000 1.000 1901184000 19A Herbs, ot her 30.000000 1.000 1.000 1901184001 19A Herbs, other

- babyfood 30.000000 1.000 1.000 1901202000 19A Lemongrass 30.000000 1.000 1.000 1901220000 19A Marjoram 30.000000 1.000 1.000 1901220001 19A Marjoram

- babyfood 30.000000 1.000 1.000 1901249000 19A Parsley, dried leaves 300.000000 1.000 1.000 1901249001 19A Parsley, dried leaves

- babyfood 300.000000 1.000 1.000 1901334000 19A Savory 30.000000 1.000 1.000 2003128000 20C Cottonseed, oil 0.750000 1.000 1.000 2003128001 20C Cottonseed, oil

- babyfood 0.750000 1.000 1.000 3100044000 31 Beef, m eat 0.020000 1.000 1.000 3100044001 31 Beef, meat

- babyfood 0.020000 1.000 1.000 3100045000 31 Beef, meat, dried 0.020000 1.920 1.000 3100046000 31 Beef, meat byproducts 0.020000 1.000 1.000 3100046001 31 Beef, meat byproducts

- babyfood 0.020000 1.000 1.000 3100047000 31 Beef, fat 0.100000 1.000 1.000 3100047001 31 Beef, fat

- babyfood 0.100000 1.000 1.00 0 3100048000 31 Beef, kidney 0.020000 1.000 1.000 3100049000 31 Beef, liver 0.020000 1.000 1.000 3100049001 31 Beef, liver

- babyfood 0.020000 1.000 1.000 3200169000 32 Goat, meat 0.020000 1.000 1.000 3200170000 32 Goat, meat byproducts 0.020000 1.000 1.000 3200171000 32 Goat, fat 0.100000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 32 of 53 3200172000 32 Goat, kidney 0.020000 1.000 1.000 3200173000 32 Goat, liver 0.020000 1.000 1.000 3300189000 33 Horse, meat 0.020000 1.000 1.000 3400290000 34 Pork, meat 0.020000 1.000 1.000 3400290001 34 Pork, meat

- babyfood 0.020000 1.000 1.000 3400291000 34 Pork, skin 0.100000 1.000 1.000 3400292000 34 Pork, mea t byproducts 0.020000 1.000 1.000 3400292001 34 Pork, meat byproducts

- babyfood 0.020000 1.000 1.000 3400293000 34 Pork, fat 0.100000 1.000 1.000 3400293001 34 Pork, fat

- babyfood 0.100000 1.000 1.000 3400294000 34 Pork, kidney 0.020000 1.000 1.000 3400295000 34 Pork, liver 0.020000 1.000 1.000 3500339000 35 Sheep, meat 0.020000 1.000 1.000 3500339001 35 Sheep, meat

- babyfood 0.020000 1.000 1.000 3500340000 35 Sheep, meat byproducts 0.020000 1.000 1.000 3500341000 35 Sheep, fat 0.100000 1.000 1.000 3500341001 35 Sheep, fat

- babyfood 0.100000 1.000 1.000 3500342000 35 Sheep, kidney 0.020000 1.000 1.000 3500343000 35 Sheep, liver 0.020000 1.000 1.000 3600222000 36 Milk, fat 0.020000 1.000 1.000 3600222001 36 Milk, fat

- baby food/infant formu 0.020000 1.000 1.000 3600223000 36 Milk, nonfat solids 0.020000 1.000 1.000 3600223001 36 Milk, nonfat solids

- baby food/in 0.020000 1.000 1.00 0 3600224000 36 Milk, water 0.020000 1.000 1.000 3600224001 36 Milk, water

- babyfood/infant form 0.020000 1.000 1.000 3600225001 36 Milk, sugar (lactose)

- baby food/ 0.020000 1.000 1.000 3800221000 38 Meat, game 0.020000 1.000 1.000 3900312000 39 Rabbit, meat 0.020000 1.000 1.000 8601000000 86A Water, direct, all sources 0.037300 1.000 1.000 8602000000 86B Water, indirect, all sources 0.037300 1.000 1.000 9500001000 O Acerola 0.900000 1.000 1.000 9500019500 O Atemoya 1.600000 1.000 1.000 9500020000 O Avocado 7.000000 1.000 1.000 9500074000 O Canistel 7.000000 1.000 1.000 9500089000 O Cherimoya 1.600000 1.000 1.000 9500151000 O Feijoa 0.900000 1.000 1.000 9500177000 O Grape, leaves 0.750000 1.000 1.000 9500178000 O Grape, raisin 1.200000 1.000 1.000 9500183000 O Guava 0.900000 1.000 1.000 9500183001 O Guava

- babyfood 0.900000 1.000 1.000 9500188000 O Hop 15.000000 1.000 1.000 9500209000 O Longan 5.000000 1.000 1.000 9500211000 O Lychee 5.000000 1.000 1.000 9500212000 O Lychee, dried 5.000000 1.850 1.000 9500214000 O Mamey apple 7.000000 1.000 1.000 9500215000 O Mango 7.000000 1.000 1.000 9500215001 O Mango

- babyfood 7.000000 1.000 1.000 9500216000 O Mango, dried 7.000000 1.000 1.000 9500217000 O Mango, juice 7.000000 1.000 1.00 0 9500217001 O Mango, juice

- babyfood 7.000000 1.000 1.000 9500245000 O Papaya 7.000000 1.000 1.000 9500245001 O Papaya

- babyfood 7.000000 1.000 1.000 9500246000 O Papay a, dried 7.000000 1.800 1.000 9500247000 O Papaya, juice 7.000000 1.500 1.000 9500252000 O Passionfruit 0.900000 1.000 1.000 9500252001 O Passionfruit

- babyfood 0.900000 1.000 1.000 9500253000 O Passionfruit, juice 0.900000 1.000 1.000 9500253001 O Passionfruit, juice

- babyfood 0.900000 1.000 1.000 9500275000 O Peppermint 25.000000 1.000 1.000 9500276000 O Peppermint, oil 25.000000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 33 of 53 9500333000 O Sapote, Mamey 7.000000 1.000 1.000 9500346000 O Soursop 1.600000 1.000 1.000 9500351000 O Spanish lime 5.000000 1.000 1.000 9500352000 O Spearmint 25.000000 1.000 1.000 9500353000 O Spearmint, oil 25.000000 1.000 1.000 9500358000 O Starfruit 0.900000 1.000 1.000 9500361000 O Sugar apple 1.600000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 34 of 53 

### Attachment 5. Bifenazate Acute Residue Results for General Population. US EPA Ver. 3.18, 03

- 08

- d DEEM
- FCID ACUTE Analysis for BIFENAZATE NHANES 2003

- 2008 2

- Day Residue file: 03_25_2014_Tolerance levels_Bifenazate_Acute.R08 Adjustment factor #2 NOT used. Ana lysis Date: 03

- 25

- 2014/14:43:03 Residue file dated: 03

- 25

- 2014/14:34:04 NOEL (Acute) = 10.000000 mg/kg body

- wt/day RAC/FF intake summed over 24 hours Run Comment: "aPAD for General Pop

- 6 mg/kg/day; aPAD for Females 13 to 49 years

- 0.1 mg/kg/day; cP AD
- 0.01 mg/kg/day"

=============================================================================== Summary calculations

-- per capita:

--- 95th Percentile

---- --- 99th Percentile

---- --- 99.9th Percentile

---- Exposure % aRfD MOE Exposure % aRfD MOE Exposure % aRfD MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- -------- Total US Population: 0.040436 0.67 247 0.083966 1.40 119 0.163136 2.72 61 All Infants: 0.079571 1.33 125 0.124819 2.08 80 0.230245 3.84 43 Children 1

- 2: 0.113582 1.89 88 0.183430 3.06 54 0.262565 4.38 38 Children 3

- 5: 0.098092 1.63 101 0.154745 2.58 64 0.275817 4.60 36 Children 6

- 12: 0.055662 0.93 179 0.098787 1.65 101 0.160533 2.68 62 Youth 13

- 19: 0.031028 0.52 322 0.058448 0.97 171 0.105872 1.76 94 Adults 20

- 49: 0.031220 0.52 320 0.054219 0.90 184 0.090788 1.51 110 Adults 50

- 99: 0.028073 0.47 356 0.048569 0.81 205 0.084429 1.41 118Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 35 of 53 

### Attachment 6. Bifenazate Acute Residue Input File for **Females 13 to 49 Years Old.** Filename: J: \ Work Files \ $ Bifenazate \ $$New \ DEEM \ Bifenazate_acute.R08 Chemical: Bifenazate RfD(Chronic): 0 mg/kg bw/day NOEL(Chronic): 1 mg/kg bw/day RfD(Acute): .1 mg/kg bw/day NOEL(Acute): 1 mg/kg bw/day Date created/last modified: 08

- 20

- 2013/11:34:42 Program ver. 3.16, 03

- 08

- d Comment: aPAD for General Pop

- 6 mg/kg/day; aPAD for Females 13 to 49 years

- 0.1 mg/kg/day; cPAD

- 0.01 mg/kg/day

----------------------------------------------------------------------------- ---

--- RDL indices and parameters for Monte Carlo Analysis: Index Dist Parameter #1 Param #2 Param #3 Comment # Code

----- ---- ------------ -------- -------- ------- 1 6 Almond.rdf 2 6 Apple.rdf 3 6 Apple_Juice. rdf 4 6 Apple_Sauce.rdf 5 6 Gbean.rdf 6 6 Gbean_babyfood.rdf 7 6 Blueberry.rdf 8 6 Cantaloupe.rdf 9 6 Cherry.rdf 10 6 Cucumber.rdf 11 6 Grape.rdf 12 6 Grape_juice.rdf 13 6 Grape_raisin.rdf 14 6 Peach.rdf 15 6 Pear.rdf 16 6 Peppers.rdf 17 6 Potato.rdf 18 6 Potato_frozen.rdf 19 6 Pecan.rdf 20 6 Squash_summer.rdf 21 6 Squash_winter.rdf 22 6 Strawberry.rdf 23 6 SweetPotato.rdf 24 6 SweetPotato_babyfood.rdf 25 6 Walnut.rdf 26 6 Watermelon.rdf 27 6 Apricot.rdf 28 6 Tomato.rdf 29 6 Plum.rdf 30 6 Guava.rdf 31 6 Avocado.rdf 32 6 Lychee.rdf 33 6 Papaya.rdf 34 6 hops.rdf 35 6 caneberries.rdf EPA Crop Commodity Name Def Res Adj.Factors RDLComment Code Grp (ppm) #1 #2 Pntr

---------- ---- ------------------------------- ---------- ------ -- ---- ---

------- 9500001000 O Acerola 0.900000 1.000 1.000 9500019500 O Atemoya 1.600000 1.000 1.000 9500020000 O Avocado 7.000000 1.000 1.000 33 9500074000 O Canistel 7.000000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 36 of 53 9500089000 O Cherimoya 1.600000 1.000 1.000 9500151000 O Feijoa 0.900000 1.000 1.000 9500177000 O Grape, leaves 0.750000 1.000 1.000 9500178000 O Grape, raisin 1.200000 1.000 1.000 13 9500183000 O Guava 0.900000 1.000 1.000 30 9500183001 O Guava

- babyfood 0.900000 1.000 1.000 30 9500188000 O Hop 15.000000 1.000 1.000 34 9500209000 O Longan 5.000000 1.000 1.000 9500211000 O Lychee 5.000000 1.000 1.000 32 9500212000 O Lychee, dried 5.000000 1.850 1.000 9500214000 O Mamey apple 7 .000000 1.000 1.000 9500215000 O Mango 7.000000 1.000 1.000 33 9500216000 O Mango, dried 7.000000 1.000 1.000 9500217000 O Mango, juice 7.000000 1.0 00 1.000 33 9500217001 O Mango, juice

- babyfood 7.000000 1.000 1.000 33 9500215001 O Mango

- babyfood 7.000000 1.000 1.000 33 9500245000 O Papaya 7.000000 1.000 1.000 33 9500246000 O Papaya, dried 7.000000 1.800 1.000 9500247000 O Papaya, juice 7.000000 1.500 1.000 33 9500245001 O Papaya

- babyfood 7.000000 1.000 1.000 33 9500252000 O Passionfruit 0.900000 1.000 1.000 30 9500253000 O Passionfruit, juice 0.900000 1.000 1.000 30 9500253001 O Passionfruit, juice

- babyfood 0.900000 1.000 1.000 30 9500252001 O Passion fruit

- babyfood 0.900000 1.000 1.000 30 9500275000 O Peppermint 25.000000 1.000 1.000 9500276000 O Peppermint, oil 25.000000 1.000 1.000 9500333000 O Sapote, Mamey 7.000000 1.000 1.000 9500346000 O Soursop 1.600000 1.000 1.000 31 9500351000 O Spanish lime 5.000000 1.000 1.000 9500352000 O Spearmint 25.000000 1.000 1.000 9500353000 O Spearmint, oil 25.000000 1.000 1.000 9500358000 O Starfruit 0.900000 1.000 1.000 33 9500361000 O Sugar appl e 1.600000 1.000 1.000 31 0103015000 1CD Arrowroot, flour 0.100000 1.000 1.000 0103015001 1CD Arrowroot, flour

- babyfood 0.100000 1.000 1.000 0103017000 1CD Artichoke, Jerusalem 0.100000 1.000 1.000 0103082000 1CD Cassava 0.100000 1.000 1.000 0103082001 1CD Cassava

- babyfood 0.100000 1.000 1.000 0103139000 1CD Dasheen, corm 0 .100000 1.000 1.000 0103166000 1CD Ginger 0.100000 1.000 1.000 0103167000 1CD Ginger, dried 0.100000 1.000 1.000 0103166001 1CD Ginger

- babyfood 0.100000 1.0 00 1.000 0103296000 1C Potato, chips 211

- Cooked; Fresh or N/S; Baked 0.001000 1.000 1.000 213

- Cooked; Fresh or N/S; Fried 0.001000 1.000 1.000 0103297000 1C Potato, dry (granules/ flakes) 211

- Cooked; Fresh or N/S; Baked 0.001000 6.500 1.000 212

- Cooked; Fresh or N/S; Boiled 0.001000 6.500 1.000 213

- Cooked; Fresh or N/S; Fried 0.001000 6.500 1.000 221

- Cooked; Frozen; Baked 0.000500 6.500 1.000 230

- Cooked; Dried; Cook Meth N/S 0.001000 6.500 1.000 232

- Cooked; Dried; Boil ed 0.001000 6.500 1.000 0103297001 1C Potato, dry (granules/ flakes)

- b 0.001000 6.500 1.000 0103298000 1C Potato, flourBifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 37 of 53 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.001000 6.500 1.000 120

- Uncooked; Frozen; Cook Meth N/S 0.000500 6.500 1.000 130

- Uncooked; Dried; Cook Meth N/S 0.001000 6.500 1.000 140

- Uncooked; Canned; Cook Meth N/S 0.001000 6.500 1.000 210

- Cooked; Fresh or N/S; Cook Meth N/S 0.001000 6.500 1.000 211

- Cooked; Fresh or N/S; Baked 0.001000 6.500 1.000 212

- Cooked; Fresh or N/S; Boiled 0.001000 6.500 1.000 213

- Cooked; Fresh or N/S; Fried 0.001000 6.500 1.000 214

- Cooked; Fresh or N/S; Fried/baked 0.001000 6.500 1.000 221

- Cooked; Frozen; Baked 0.000500 6.500 1.000 222

- Cooked; Frozen; Boiled 0.000500 6.500 1.000 223

- Cooked; Frozen; Fried 0.000500 6.500 1.000 230

- Cooked; Dried; Cook Meth N/S 0.001000 6.500 1.000 231

- Cooked; Dried; Baked 0.001000 6.500 1.000 232

- Cooked; Dried; Boiled 0.001000 6.500 1.000 233

- Cooked; Dried; Fried 0.001000 6.500 1.000 240

- Cooked; Canned; Cook Meth N/S 0.001000 6.500 1.000 242

- Cooked; Canned; Boiled 0.001000 6.500 1.000 250

- Cooked; Cured etc; Cook Meth N/ S 0.001000 6.500 1.000 251

- Cooked; Cured etc; Baked 0.001000 6.500 1.000 252

- Cooked; Cured etc; Boiled 0.001000 6.500 1.000 253

- Cooked; Cured etc; Fried 0.001000 6.500 1.000 0103298001 1C Potato, flour

- babyfood 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.001000 6.500 1.000 130

- Uncooked; Dried; Cook Meth N/S 0.001000 6.500 1.000 211

- Cooked; Fresh or N/S; Baked 0.001000 6.500 1.000 240

- Cooked; Canned; Cook Meth N/S 0.001000 6.500 1.000 0103300000 1C Potato, tuber, w/o peel 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 1.000 17 210

- Cooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 1.000 17 211

- Cooked; Fresh or N/S; Baked 0.100000 1.000 1.000 17 212

- Cooked; Fresh or N/S; Boiled 0.100000 1.000 1.000 17 213

- Cooked; Fresh or N/S; Fried 0.100000 1.000 1.000 17 221

- Cooked; Frozen; Baked 0.100000 1.000 1.000 18 223

- Cooked; Frozen; Frie d 0.100000 1.000 1.000 18 232

- Cooked; Dried; Boiled 0.100000 1.000 1.000 17 233

- Cooked; Dried; Fried 0.100000 1.000 1.000 17 240

- Cooked; Canned; Cook Meth N/S 0.100000 1.000 1.000 17Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 38 of 53 242

- Cooked; Canned; Boiled 0.100000 1.000 1.000 17 252

- Cooked; Cured etc; Boiled 0.100000 1.000 1.000 17 0103300001 1C Potato, tuber, w/o peel

- babyfood 0.100000 1.000 1.000 17 0103299000 1C Potato, tuber, w/peel 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 1.000 17 210

- Cooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 1.000 17 211

- Cooked; Fresh or N/S; Baked 0.100000 1.000 1.000 17 212

- Cooked; Fresh or N/S; Boiled 0.100000 1.000 1.000 17 213

- Cooked; Fresh or N/S; Fried 0.100000 1.000 1.000 17 0103299001 1C Potato, tuber, w/peel

- babyfood 0.100000 1.000 1.000 17 0103366000 1CD Sweet potato 0.100000 1.000 1.000 23 0103366001 1CD Sweet potato

- babyfood 0.100000 1.000 1.000 24 0103371000 1CD Tanier, corm 0.100000 1.000 1.000 0103387000 1CD Turmeric 0.100000 1.000 1.000 0103407000 1CD Yam bean 0.100000 1.000 1.000 23 0103406000 1CD Yam, true 0.100000 1.000 1.000 23 0603035000 6C Bean, great northern, seed 0.600000 1.000 1.000 0603030000 6C Bean, black, seed 0.600000 1.000 1.000 0603032000 6C Bean, broad, seed 0.600000 1.000 1.000 0602031000 6B Bean, broad, succulent 0.700000 1.000 1.000 5 0603034000 6C Bean, cowpea, seed 0.600000 1.000 1.000 0602033000 6B Bean, cowp ea, succulent 212

- Cooked; Fresh or N/S; Boiled 0.700000 1.000 1.000 5 222

- Cooked; Frozen; Boiled 0.700000 1.000 1.000 5 242

- Cooke d; Canned; Boiled 0.700000 1.000 1.000 5 0603036000 6C Bean, kidney, seed 0.600000 1.000 1.000 0603038000 6C Bean, lima, seed 0.600000 1.000 1.000 0602037000 6B Bean, lima, succulent 0.700000 1.000 1.000 5 0603039000 6C Bean, mung, seed 0.600000 1.000 1.000 0603040000 6C Bean, navy, seed 0.600000 1.000 1.000 0603041000 6C Bean, pink, seed 0.6 00000 1.000 1.000 0603042000 6C Bean, pinto, seed 0.600000 1.000 1.000 0601043000 6A Bean, snap, succulent 6.000000 1.000 1.000 5 0601043001 6A Bean, snap, succulent

- babyfood 6.000000 1.000 1.000 6 0603099000 6C Chickpea, flour 0.600000 1.000 1.000 0603098000 6C Chickpea, seed 0.600000 1.000 1.000 0603098001 6C Chickpea, seed

- babyfood 0.600000 1.000 1.000 0603182000 6C Guar, seed 0.600000 1.000 1.000 0603182001 6C Guar, seed

- babyfood 0.600000 1.000 1.000 0603203000 6C Lentil, seed 0.600000 1.000 1.000 0603256000 6C Pea, dry 0.600000 1.000 1.000 0603256001 6C Pea, dry

- babyfood 0.600000 1.000 1.000 0601257000 6A Pea, edible podded, succulent 6.000000 1.000 1.000 5 0603258000 6C Pea, pigeon, seed 0.600000 1.000 1.000 0602259000 6B Pea, pigeon, succulent 0.700000 1.000 1.000 5 0602255000 6B Pea, succulent 0.700000 1.000 1.000 5 0602255001 6B Pea, succu lent

- babyfood 0.700000 1.000 1.000 6 0600347000 6 Soybean, seed 0.700000 1.000 1.000 0802148000 8BC Eggplant 2.000000 1.000 1.000 0802234000 8BC Okra 2.000000 1.000 1.000 0802270000 8B Pepper, bell 2.000000 1.000 1.000 16 0802271000 8B Pepper, bell, dried 0.000800 1.000 1.000 0802271001 8B Pepper, bell, dried

- babyfood 0 .000800 1.000 1.000 0802270001 8B Pepper, bell

- babyfood 2.000000 1.000 1.000 16Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 39 of 53 0802272000 8BC Pepper, nonbell 2.000000 1.000 1.000 16 0802273000 8BC Pepper, nonbell, dried 0.000800 1.0 00 1.000 0802272001 8BC Pepper, nonbell

- babyfood 2.000000 1.000 1.000 16 0801374000 8A Tomatillo 2.000000 1.000 1.000 28 0801375000 8A Tomato 2.000000 1.000 1.000 28 0801380000 8A Tomato, Tree 2.000000 1.000 1.000 28 0801378000 8A Tomato, dried 0.110000 14.300 0.100 0801378001 8A Tomato, dried

- babyfood 0.110000 14.300 0.100 0801379000 8A Tomato, juice 2.000000 1.500 1.000 28 0801376000 8A Tomato, paste 0.110000 5.400 0.100 0801376001 8A Tomato, paste

- babyfood 0.110000 5.400 0.100 0801377000 8A Tomato, puree 0.110000 3.300 0.100 0801377001 8A Tomato, puree

- babyfood 0.110000 3.300 0.100 0801375001 8A Tomato

- babyfood 2.000000 1.000 1.000 28 0902021000 9B Balsam pear 0.750000 1.000 1.000 20 0901075000 9A Cantaloupe 0.750000 1.000 1.000 8 0902088000 9B Chayote, fruit 0.750000 1.000 1.000 20 0902102000 9B Chinese waxgourd 0.750000 1.000 1.000 20 0902135000 9B Cucumber 0.750000 1.000 1.000 10 0901187000 9A Honeydew melon 0.750000 1.000 1.000 8 0902308000 9B Pumpkin 0.750000 1.000 1.000 0902309000 9B Pumpkin, seed 0.750000 1.000 1.000 0902356000 9B Squash, summer 0.750000 1.000 1.000 20 0902356001 9B Squash, summer

- babyfood 0.750000 1.000 1.000 20 0902357000 9B Squash, winter 0.750000 1.000 1.000 21 0902357001 9B Squash, winter

- babyfood 0.750000 1.000 1.000 21 0901399000 9A Watermelon 0 .750000 1.000 1.000 26 0901400000 9A Watermelon, juice 0.750000 1.000 1.000 26 1100009000 11 Apple, dried 0.001000 8.000 1.000 1100009001 11 Apple, dried

- babyfood 0.001000 8.0 00 1.000 1100007000 11 Apple, fruit with peel 0.220000 1.000 1.000 2 1100010000 11 Apple, juice 0.220000 1.000 1.000 3 1100010001 11 Apple, juice

- babyfood 0.220000 1.000 1.000 3 1100008000 11 Apple, peeled fruit 0.220000 1.000 1.000 2 1100008001 11 Apple, peeled fruit

- babyfood 0.220000 1.000 1.000 2 1100011000 11 Apple, sauce 0.220000 1.000 1.000 4 1100011001 11 Apple, sauce

- babyfood 0.220000 1.000 1.000 4 1100129000 11 Crabapple 0.750000 1.000 1.000 1100173500 11 Goji berry 2.000000 1.000 1.000 1100210000 11 Loquat 0.750000 1.000 1.000 1100266000 11 Pear 0.150000 1.000 1.000 15 1100267000 11 Pear, dried 0.150000 6.250 1.000 15 1100268000 11 Pear, juice 0.150000 1.000 1.000 15 1100268001 11 Pear, juice

- babyfood 0.150000 1.000 1.000 15 1100266001 11 Pear

- babyfood 0.150000 1.000 1.000 15 1100310000 11 Quince 0.750000 1.000 1.000 1202012000 12B Apricot 2.500000 1.000 1.000 27 1202013000 12B Apricot, dried 2.500000 6.000 1.000 27 1202014000 12B Apricot, j uice 2.500000 1.000 1.000 27 1202014001 12B Apricot, juice

- babyfood 2.500000 1.000 1.000 27 1202012001 12B Apricot

- babyfood 2.500000 1.000 1.000 27 1201090000 12A Cherry 2.500000 1.000 1.000 9 1201091000 12A Cherry, juice 2.500000 1.500 1.000 9 1201091001 12A Cherry, juice

- babyfood 2.500000 1.500 1.000 9 1201090001 12A Cherry

- babyfood 2 .500000 1.000 1.000 9 1202230000 12B Nectarine 2.500000 1.000 1.000 14 1202260000 12B Peach 2.500000 1.000 1.000 14 1202261000 12B Peach, dried 2.500000 7.0 00 1.000 14 1202261001 12B Peach, dried

- babyfood 2.500000 7.000 1.000 14 1202262000 12B Peach, juice 2.500000 1.000 1.000 14Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 40 of 53 1202262001 12B Peach, juice

- babyfood 2.500000 1.000 1.000 14 1202260001 12B Peach

- babyfood 2.500000 1.000 1.000 14 1203285000 12C Plum 0.200000 1.000 1.000 29 1203287000 12C Plum, prune, dried 0.200000 5.000 1.000 29 1203287001 12C Plum, prune, dried

- babyfood 0.200000 5.000 1.000 29 1203286000 12C Plum, prune, fresh 0.200000 5.000 1.000 29 1203286001 12C Plum, prune, fresh

- babyfood 0.200000 5.000 1.000 29 1203288000 12C Plum, p rune, juice 0.200000 1.400 1.000 29 1203288001 12C Plum, prune, juice

- babyfood 0.200000 1.400 1.000 29 1203285001 12C Plum

- babyfood 0.200000 1.000 1.000 29 1301055000 13A Blackberry 5.000000 1.000 1.000 35 1301056000 13A Blackberry, juice 5.000000 1.000 1.000 35 1301056001 13A Blackberry, juice

- babyfood 5.000000 1.000 1.000 35 1301058000 13 A Boysenberry 5.000000 1.000 1.000 35 1307130000 13G Cranberry 1.500000 1.000 1.000 22 1307131000 13G Cranberry, dried 1.500000 1.000 1.000 22 1307132000 13G Cranberry, juice 1.500000 1.100 1.000 22 1307132001 13G Cranberry, juice

- babyfood 1.500000 1.100 1.000 22 1307130001 13G Cranberry

- babyfood 1.500000 1.000 1.000 22 1304175000 13D Grape 1.000000 1.000 1.000 11 1304176000 13D Grape, juice 1.000000 1.000 1.000 12 1304176001 13D Grape, juice

- babyfood 1.000000 1.000 1.000 12 1304179000 13D Grape, wine and sherry 1 .000000 1.000 1.000 12 1301208000 13A Loganberry 5.000000 1.000 1.000 35 1301320000 13A Raspberry 5.000000 1.000 1.000 35 1301321000 13A Raspberry, juice 5.000000 1.0 00 1.000 35 1301321001 13A Raspberry, juice

- babyfood 5.000000 1.000 1.000 35 1301320001 13A Raspberry

- babyfood 5.000000 1.000 1.000 35 1307359000 13G Strawberry 1.500000 1.000 1.000 22 1307360000 13G Strawberry, juice 1.500000 1.000 1.000 22 1307360001 13G Strawberry, juice

- babyfood 1.500000 1.000 1.000 22 1307359001 13G Strawberry

- babyfood 1.500000 1.000 1.000 22 1400003000 14 Almond 0.200000 1.000 1.000 1 1400004000 14 Almond, oil 0.000500 1.000 1.000 1400004001 14 Almond, oil

- babyfood 0.000500 1.000 1.000 1400003001 14 Almond

- babyfood 0.200000 1.000 1.000 1 1400059000 14 Brazil nut 0.200000 1.000 1.000 1400068000 14 Butternut 0.200000 1.000 1.000 1400081000 14 Cashew 0.200000 1.000 1.000 1400092000 14 Chestnut 0.200000 1.000 1.000 1400155000 14 Hazelnut 0.200000 1.000 1.000 1400156000 14 Hazelnut, oil 0.000500 1.000 1.000 1400185000 14 Hickory nut 0.200000 1.000 1.000 1400213000 14 Macadamia nut 0.200000 1.000 1.000 1400269000 14 Pecan 0.200000 1.000 1.000 19 1400278000 14 Pine nut 0.200000 1.000 1.000 1400282000 14 Pistachio 0.200000 1.000 1.000 1400391000 14 Walnut 0.200000 1.000 1.000 25 2003128000 20C Cottonseed, oil 0.750000 1.000 1.000 2003128001 20C Cottonseed, oil

- babyfood 0.750000 1.000 1.000 3100047000 31 Beef, fat 0 .100000 1.000 1.000 3100047001 31 Beef, fat

- babyfood 0.100000 1.000 1.000 3100048000 31 Beef, kidney 0.020000 1.000 1.000 3100049000 31 Beef, liver 0.020000 1.0 00 1.000 3100049001 31 Beef, liver

- babyfood 0.020000 1.000 1.000 3100044000 31 Beef, meat 0.020000 1.000 1.000 3100046000 31 Beef, meat byproducts 0.020000 1.000 1.000 3100046001 31 Beef, meat byproducts

- babyfood 0.020000 1.000 1.000 3100045000 31 Beef, meat, dried 0.020000 1.920 1.000 3100044001 31 Beef, meat

- babyfood 0.020000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 41 of 53 3200171000 32 Goat, fat 0.100000 1.000 1.000 3200172000 32 Goat, kidney 0.020000 1.000 1.000 3200173000 32 Goat, liver 0.020000 1.000 1.000 3200169000 32 Goat, m eat 0.020000 1.000 1.000 3200170000 32 Goat, meat byproducts 0.020000 1.000 1.000 3300189000 33 Horse, meat 0.020000 1.000 1.000 3400293000 34 Pork, fat 0.100000 1.000 1.000 3400293001 34 Pork, fat

- babyfood 0.100000 1.000 1.000 3400294000 34 Pork, kidney 0.020000 1.000 1.000 3400295000 34 Pork, liver 0.020000 1.000 1.000 3400290000 34 Pork, meat 0.020000 1.000 1.000 3400292000 34 Pork, meat byproducts 0.020000 1.000 1.000 3400292001 34 Pork, meat byproducts

- babyfood 0.020000 1.000 1.000 3400290001 34 Pork, meat

- babyfood 0.020000 1.000 1.000 3400291000 34 Pork, skin 0.100000 1.000 1.000 3500341000 35 Sheep, fat 0.100000 1.000 1.000 3500341001 35 Sheep, fat

- babyfood 0.100000 1.000 1.000 3500342000 35 Sheep, kidney 0.020000 1.000 1.000 3500343000 35 Sheep, liver 0 .020000 1.000 1.000 3500339000 35 Sheep, meat 0.020000 1.000 1.000 3500340000 35 Sheep, meat byproducts 0.020000 1.000 1.000 3500339001 35 Sheep, meat

- babyfood 0.020000 1.0 00 1.000 3600222000 36 Milk, fat 0.020000 1.000 1.000 3600222001 36 Milk, fat

- baby food/infant formu 0.020000 1.000 1.000 3600223000 36 Milk, nonfat solids 0.020000 1.000 1.000 3600223001 36 Milk, nonfat solids

- baby food/in 0.020000 1.000 1.000 3600225001 36 Milk, sugar (lactose)

- baby food/ 0.020000 1.000 1.000 3600224000 36 Milk, water 0.020000 1.000 1.000 3600224001 36 Milk, water

- babyfood/infant form 0.020000 1.000 1.000 3800221000 38 Meat, game 0.020000 1.000 1.000 3900312000 39 Rabbit, meat 0.020000 1.000 1.000 8601000000 86A Water, direct, all sources 0.037300 1.000 1.000 8602000000 86B Water, indirect, all sources 0.037300 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 42 of 53 

### Attachment 7. Bifenazate Acute RDFs. Note: Titles, s paces , and commas were added and hard returns deleted betw een data points in RDF files by the reviewer in order to condense the information. **Almond: (RDF 1)** Almond(10 %CT) 2007

- 08 PDP data TOTALZ=492 TOTALLOD= 55 LODRES=0.005 **Apple: (RDF 2)** Apple(5 %CT) 2009 PDP data TOTALZ=609 TOTALLOD=32 LODRES=0.02 **Apple Juice: (RDF 3)** Apple Juice(5 %CT) 2007

- 08 PDP data TOTALZ=203 TOTALLOD=11 LODRES=0.01 **Apple Sauce: (RDF 4)** Apple Sauce(5 %CT) 2006 PDP data TOTALZ=2 05 TOTALLOD=11 LODRES=0.01 **Green Beans: (RDF 5)** Green Beans(2.5 %CT) 2008 PDP data TOTALZ=21 0 TOTALLOD=5 LODRES=0.01 **Green Beans babyfood** : **(RDF 6)** Green Beans babyfood(2.5 %CT) 2010 PDP data TOTALZ=1 87 TOTALLOD=5 LODRES=0.0015 **Blueberry: (RDF 7)** Blueberry(30 %CT) 2008 PDP data TOTALZ= 148 TOTALLOD= 63 LOD RES=0.03 **Note: This RDF File was not used in the analysis.**  **Cantaloupe: (RDF 8)** Cantaloupe(2.5 %CT) 2004

- 05 PDP data TOTALZ=4 71 TOTALLOD=12 LODRES=0.007
**Cherry: (RDF 9)** Cherry (5 %CT) 2007 PDP data TOTALZ=1 16 TOTALLOD=6 LODRES=0.01 **Cucumber: (RDF 10)** Cucumber (5 %CT) 2009

- 10 PDP data TOTALZ=5 53 TOTALLOD=28 LODRES=0.02 0.0 2 **Grape: (RDF 11)** Grape(20 %CT) 2009

- 10 PDP data TOTALZ= 1 1 9 1 TOTALLOD=2 7 8 LODRES=0.02 0.11 , 0.073, 0.064, 0.052, 0.042, 0.019, 0.015, 0.014, 0.012, 0.005, 0.005, 0.005, 0.077, 0.07, 0.059, 0.045, 0.033, 0.033, 0.029, 0.027 **Grape Juice: (RDF 12)** Grape Juice(20 %CT) 2008 PDP data TOTALZ= 171 TOTALLOD=43 LODRES=0.01

**Grape raisin: (RDF 13)** Grape raisin(20 %CT) 2009

- 10 PDP data TOTALZ=173 TOTALLOD=3 8 LODRES=0.0 1 0.067, 0.067, 0.067, 0.067, 0.067 **Peach: (RDF 14)** Peach(20 %CT) 2007

- 08 PDP data TOTALZ= 805 TOTALLOD=1 90 LODRES=0.015 0.084, 0.05, 0.05, 0.033, 0.11, 0.05, 0.05, 0.05, 0.05, 0.033, 0.033 **Pear: (RDF 15)** Pear(30 %CT) 2004

- 05 PDP data TOTALZ=264 TOTALLOD= 109 LODRES=0.01 0.033, 0.033, 0.033, 0.033 **Pepper sweet bell: (RDF 16)** Pepper sweet bell(10 %CT) 2010 PDP data TOTALZ= 670 TOTALLOD=74 LODRES=0.0085Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 43 of 53 **Potato: (RDF 17)** Potato(5 %CT) 2008

- 09 PDP data TOTALZ=405 TOTALLOD=21 LODRES=0.02 **Potato frozen: (RDF 18)** Potato frozen(5 %CT) 2006

- 07 PDP data TOTALZ=1105 TOTALLOD=5 8 LODRES=0.01 **Pecan: (RDF 19)** Pecan(2.5 %CT) Almond 2007

- 08 PDP data TOTALZ=533 TOTALLOD=14 LODRES=0.005 **Squash, summer: (RDF 20)** Squash, summer(2.5 %CT) 2006

- 08 PDP data TOTALZ=415 TOTALLOD=11 LODRES=0.01 **Squash, winter: (RDF 21)** Squash, winter(2.5 %CT) 2005

- 06 PDP data TOTALZ=1 299 TOTALLOD= 33 LODRES=0.02 **RDF 22 see below**

**Strawberry: (RDF 22)** Strawberry(65 %CT) 2008

- 09 PDP data TOTALZ=504 TOTALLOD=777 LODRES=0.03 0.55, 0.52, 0.46, 0.37, 0.32, 0.31, 0.23, 0.22, 0.22, 0.2, 0.18, 0.18, 0.18, 0.18, 0.16, 0.16, 0.15, 0.15, 0.14, 0.14, 0.14, 0.14, 0.14, 0.14, 0.13, 0.13, 0.13, 0.12, 0.11, 0.1, 0.096, 0.091, 0.088, 0.088, 0.085, 0.084, 0.083, 0.079, 0.077, 0.076, 0.07, 0.07, 0.069, 0.033, 0.033, 0.033, 0.033, 0. 033, 0.033, 0.033, 0.033, 0.033, 0.033, 0.033, 0.03, 0.87, 0.81, 0.67, 0.62, 0.57, 0.56, 0.53, 0.5, 0.49, 0.45, 0.42, 0.4, 0.34, 0.33, 0.33, 0.32, 0.3, 0.29, 0.25, 0.23, 0.222, 0.22, 0.21, 0.19, 0.16, 0.16, 0.16, 0.15, 0.15, 0.15, 0.15, 0.15, 0.14, 0.14, 0 .13, 0.13, 0.12, 0.12, 0.12, 0.11, 0.11, 0.11, 0.1, 0.1, 0.097, 0.094, 0.093, 0.079, 0.077, 0.073, 0.073, 0.07, 0.07, 0.07, 0.07, 0.07, 0.07, 0.07, 0.07, 0.07, 0.07, 0.07 , 0.07 , 0.07 , 0.07 , 0.07 , 0.07 , 0.07 , 0.065 , 0.064 , 0.063 , 0.059 , 0.055 , 0.053 , 0.053 , 0.048 , 0.045 , 0.042 , 0.04 , 0.04 , 0.04 , 0.039 , 0.038 , 0.036 , 0.036 , 0.036 , 0.035 , 0.035 , 0.034 , 0.034 , 0.034 , 0.033 , 0.032 , 0.031 , 0.031 , 0.029 , 0.029 , 0.029 , 0.026 , 0.025 , 0.023 , 0.022 , 0.022 , 0.019 , 0.018 **Sweet Potato: (RDF 23)** Sweet Potato(5 %CT) 200 9

- 10 PDP data TOTALZ= 725 TOTALLOD= 38 LODRES=0.02 **Sweet Potato babyfood: (RDF 24)** Sweet Potato babyfood(5 %CT) 2009

- 10 PDP data TOTALZ=1 8 1 TOTALLOD=10 LODRES=0.015 **Walnut: (RDF 25)** Walnut(5 %CT) 2007

- 08 PDP data TOTALZ=520 TOTALLOD=27 LODRES=0.005 **Watermelon: (RDF 26)** Watermelon(2.5 %CT) 2005, 2006, 2010 PDP data TOTALZ= 362 TOTALLOD= 9 LODRES=0.0 2 **Apricot: (RDF 27)** Apricot(10 %CT) Peach data 2007

- 08 PDP data TOTALZ=8 88 TOTALLOD= 88 LODRES=0.015 0.084, 0.05, 0.05, 0.033, 0.11, 0.05, 0.05, 0.05, 0.05, 0.033, 0.033 **Tomato: (RDF 28)** Tomato(10 %CT) FT data TOTALZ=90 TOTALNZ=10 0.185, 0.14, 0.065, 0.035, 0.095, 0.035, 0.04, 0.135, 0.05, 0.345Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 44 of 53 **Plum: (RDF 29)** Plum (20 %CT) FT data TOTALZ=28 TOTALNZ=7 0.13, 0.01, 0.035, 0.06, 0.035, 0.03, 0.035 **Guav a: (RDF 30)**  Guava (100 %CT) FT data TOTALZ=0 TOTALNZ=6 0.26, 0.30, 0.039, 0.28, 0.24, 0.21 **Avocado: (RDF 31)** Avocado (100 %CT) translated from sugar apples FT data TOTALZ=0 TOTALNZ=6 0.9890, 0.2284, 0.2097, 0.1504, 0.2297, 0.08628 **Lychee: (RDF 32)** Lychee (100 %CT) FT data TOTALZ=0 TOTALNZ=6 2.8, 2.9, 3.6, 3.7, 2.2, 3.3
**Papaya: (RDF 33)** Papaya (100 %CT) FT data TOTALZ=0 TOTALNZ=6 0.11, 0.14, 0.62, 1.89, 0.76, 0.81 **Hops : (RDF 34)**  Hops (100 %CT) Crop field trial data TOTALZ=0 TOTALNZ=3 9.31, 7.79, 7.10 **Caneberries: (RDF 35)** Caneberries FT Data 30%CT TotalNZ = 8 TotalZ = 19 1.9, 3.25, 1.55, 1.45, 2.0, 1.3, 2.3, 3.55Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 45 of 53 

### Attachment 7. Bifenazate Acute Results for Females 13 to 49 Years Old.

US EPA Ver. 3.18, 03

- 08

- d DEEM
- FCID ACUTE Analysis for BIFENAZATE NHANES 2003

- 2008 2

- Day Residue file: 03_25_2014_Bifenazate_Acute.R08 Adjustment factor #2 used. Analysis Date: 03

- 28

- 2014/10:58:10 Residue file dated: 03

- 25

- 2014/15: 05:16 NOEL (Acute) = 1.000000 mg/kg body

- wt/day RAC/FF intake summed over 24 hours MC iterations = 100; MC list in residue file; MC seed = 1000; RNG = MS VB Run Comment: "aPAD for General Pop

- 6 mg/kg/day; aPAD for Females 13 to 49 ye ars - 0.1 mg/kg/da y; cPAD
- 0.01 mg/kg/day"

=============================================================================== Summary calculations

-- per capita:

--- 95th Percentile

---- --- 99th Percentile

---- --- 99.9th Percentile

---- Exposure % aRfD MOE Ex posure % aRfD MOE Exposure % aRfD MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- -------- Female 13

- 49: 0.002774 2.77 360 0.004394 4.39 227 0.009941 9.94 100Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 46 of 53 

### Attachment 9. Bifenazate Chronic Residue Input File. Filename: J: \ Work Files \ $ Bifenazate \ $$New \ DEEM \ 03_25_2014_Tolerance levels_Bifenazate_chronic.R08 Chemical: Bifenazate RfD(Chronic): 0 mg/kg bw/day NOEL(Chronic): 1 mg/kg bw/day RfD(Acute): 0 mg/kg b w/day NOEL(Acute): 10 mg/kg bw/day Date created/last modified: 08

- 20

- 2013/11:37:52 Program ver. 3.16, 03

- 08

- d Comment: aPAD for General Pop

- 6 mg/kg/day; aPAD for Females 13 to 49 years

- 0.1 mg/kg/day; cPAD

- 0.01 mg/kg/day

---------------------- ---------------------------------------------------------- EPA Crop Def Res Adj.Factors Comment Code Grp Commodity Name (ppm) #1 #2

---------- ---- ---------------------- --------- ---------- ------ ------ ---- 9500001000 O Acerola 0.900000 1.000 1.000 9500019500 O Atemoya 1.600000 1.000 1.000 9500020000 O Avocado 7.000000 1.000 1.000 9500074000 O Canistel 7.000000 1.000 1.000 9500089000 O Cherimoya 1.600000 1.000 1.000 9500151000 O Feijoa 0.900000 1.000 1.000 9500177 000 O Grape, leaves 0.750000 1.000 0.100 9500178000 O Grape, raisin 1.200000 1.000 0.100 9500183000 O Guava 0.900000 1.000 1.000 9500183001 O Guava

- babyfood 0.900000 1.000 1.000 9500188000 O Hop 15.000000 1.000 1.000 9500209000 O Longan 5.000000 1.000 1.000 9500211000 O Lychee 5.000000 1.000 1.000 9500212000 O Lychee, dried 5.000000 1.850 1.000 9500214000 O Mamey apple 7.000000 1.000 1.000 9500215000 O Mango 7.000000 1.000 1.000 9500216000 O Mango, dried 7.000000 1.000 1.000 9500217000 O Mango, juice 7.000000 1.000 1.000 9500217001 O Mango, juice

- babyfood 7.000000 1.000 1.000 9500215001 O Mango

- babyfood 7.000000 1.000 1.000 9500245000 O Papaya 7.000000 1.000 1.000 9500246000 O Papaya, dried 7.000000 1.800 1.000 9500247000 O Papaya, juice 7.000000 1.500 1.000 9500245001 O Papaya

- babyfood 7.000000 1.000 1.000 9500252000 O Passionfruit 0.900000 1.000 1.000 9500253000 O Passion fruit, juice 0.900000 1.000 1.000 9500253001 O Passionfruit, juice

- babyfood 0.900000 1.000 1.000 9500252001 O Passionfruit

- babyfood 0.900000 1.000 1.000 9500275000 O Peppermint 25.000000 1.000 1.000 9500276000 O Peppermint, oil 25.000000 1.000 1.000 9500333000 O Sapote, Mamey 7.000000 1.000 1.000 9500346000 O Soursop 1.600000 1.000 1.00 0 9500351000 O Spanish lime 5.000000 1.000 1.000 9500352000 O Spearmint 25.000000 1.000 1.000 9500353000 O Spearmint, oil 25.000000 1.000 1.000 9500358000 O Starf ruit 0.900000 1.000 1.000 9500361000 O Sugar apple 1.600000 1.000 1.000 0103015000 1CD Arrowroot, flour 0.100000 1.000 1.000 0103015001 1CD Arrowroot, flour

- babyfood 0.100000 1.000 1.000 0103017000 1CD Artichoke, Jerusalem 0.100000 1.000 1.000 0103082000 1CD Cassava 0.100000 1.000 1.000 0103082001 1CD Cassava

- b abyfood 0.100000 1.000 1.000 0103139000 1CD Dasheen, corm 0.100000 1.000 1.000 0103166000 1CD Ginger 0.100000 1.000 1.000 0103167000 1CD Ginger, dried 0.100000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 47 of 53 0103166001 1CD Ginger

- babyfood 0.100000 1.000 1.000 0103296000 1C Potato, chips 211

- Cooked; Fresh or N/S; Baked 0.100000 1.000 0. 050 213

- Cooked; Fresh or N/S; Fried 0.100000 1.000 0.050 0103297000 1C Potato, dry (granules/ flakes) 211

- Cooked; Fresh or N/S; Baked 0.100000 6.500 0.050 212

- Cooked; Fresh or N/S; Boiled 0.100000 6.500 0.050 213

- Cooked; Fresh or N/S; Fried 0.100000 6.500 0.050 221

- Cooked; Frozen; Baked 0.100000 6.500 0.050 230

- Cooked; Dried; Cook Meth N/S 0.100000 6.500 0.05 0 232

- Cooked; Dried; Boiled 0.100000 6.500 0.050 0103297001 1C Potato, dry (granules/ flakes)

- b 0.100000 6.500 0.050 0103298000 1C Potato, flour 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.100000 6.500 0.050 120

- Uncooked; Frozen; Cook Meth N/S 0.100000 6.500 0.050 130

- Uncooked; Dried; Cook Meth N/S 0.100000 6.500 0.050 140

- Uncooked; Canned; Cook Meth N/S 0.100000 6.500 0.050 210

- Cooked; Fresh or N/S; Co ok Meth N/S 0.100000 6.500 0.050 211

- Cooked; Fresh or N/S; Baked 0.100000 6.500 0.050 212

- Cooked; Fresh or N/S; Boiled 0.100000 6.500 0.050 213

- Cooked; Fresh or N/S; Fried 0.100000 6.500 0.050 214

- Cooked; Fresh o r N/S; Fried/baked 0.100000 6.500 0.050 221

- Cooked; Frozen; Baked 0.100000 6.500 0.050 222

- Cooked; Frozen; Boiled 0.100000 6.500 0.050 223

- Cooked; Frozen; Fried 0.100000 6.500 0.050 230

- Cooked; Dried; Cook Meth N/S 0.100000 6.500 0.050 231

- Cooked; Dried; Baked 0.100 000 6.500 0.050 232

- Cooked; Dried; Boiled 0.100000 6.500 0.050 233

- Cooked; Dried; Fried 0.100000 6.500 0.050 240

- Cooked; Canned; Cook Meth N/S 0.100000 6.500 0.050 242

- Cooked; Canned; Boiled 0.100000 6.500 0.050 250

- Cooked; Cured etc; Cook Meth N/S 0.100000 6.500 0.050 251

- Cooked; Cured etc; Baked 0.100000 6.500 0.050 252

- Cooked; Cured etc; Boiled 0.100000 6.500 0.050 253

- Co oked; Cured etc; Fried 0.100000 6.500 0.050 0103298001 1C Potato, flour

- babyfood 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.100000 6.500 0.050 130

- Unco oked; Dried; Cook Meth N/S 0.100000 6.500 0.050 211

- Cooked; Fresh or N/S; Baked 0.100000 6.500 0.050Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 48 of 53 240

- C ooked; Canned; Cook Meth N/S 0.100000 6.500 0.050 0103300000 1C Potato, tuber, w/o peel 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 0.050 210

- Cooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 0.050 211

- Cooked; Fresh or N/S; Baked 0.100000 1.000 0.050 212

- Cooked; Fresh or N/S; Boiled 0.100000 1.000 0.050 213

- Cooked; Fresh or N/S; Fried 0.100000 1.000 0.050 221

- Cooked; Frozen; Baked 0.100000 1.000 0.050 223

- Cooked; Frozen; Fried 0.100000 1.000 0.050 232

- Cooked; Dried; Boiled 0.100000 1.0 00 0.050 233

- Cooked; Dried; Fried 0.100000 1.000 0.050 240

- Cooked; Canned; Cook Meth N/S 0.100000 1.000 0.050 242

- Cooked; Canned; Boiled 0.100000 1.000 0.050 252

- Cooked; Cured etc; Boiled 0.100000 1.000 0.050 0103300001 1C Potato, tuber, w/o peel

- babyfood 0.100000 1.000 0.050 0103299000 1C Potato, t uber, w/peel 110

- Uncooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 0.050 210

- Cooked; Fresh or N/S; Cook Meth N/S 0.100000 1.000 0.050 211

- Cooked; Fresh or N/S; Baked 0.100000 1.000 0.050 212

- Cooked; Fresh or N/S; Boiled 0.100000 1.000 0.050 213

- Cooked; Fresh or N/S; Fried 0.100000 1.000 0.050 0103299001 1C Potato, tuber, w/peel

- babyfood 0.100000 1.000 0.050 0103366000 1CD Swe et potato 0.100000 1.000 1.000 0103366001 1CD Sweet potato

- babyfood 0.100000 1.000 1.000 0103371000 1CD Tanier, corm 0.100000 1.000 1.000 0103387000 1CD Turmeric 0.100000 1.000 1.000 0103407000 1CD Yam bean 0.100000 1.000 1.000 0103406000 1CD Yam, true 0.100000 1.000 1.000 0603035000 6C Bean, great northern, seed 0.600000 1.000 1.000 0603030000 6C Bean, black, seed 0.600000 1.000 1.000 0603032000 6C Bean, broad, seed 0.600000 1.000 1.000 0602031000 6B Bean, broad, succulent 0.700000 1.000 1.000 0603034000 6C B ean, cowpea, seed 0.600000 1.000 1.000 0602033000 6B Bean, cowpea, succulent 212

- Cooked; Fresh or N/S; Boiled 0.700000 1.000 1.000 222

- Cooked; Frozen; Boiled 0.700000 1.000 1.000 242

- Cooked; Canned; Boiled 0.700000 1.000 1.000 0603036000 6C Bean, kidney, seed 0.600000 1.000 1.000 0603038000 6C Bean, lim a, seed 0.600000 1.000 1.000 0602037000 6B Bean, lima, succulent 0.700000 1.000 1.000 0603039000 6C Bean, mung, seed 0.600000 1.000 1.000 0603040000 6C Bean, navy, seed 0.600000 1.000 1.000 0603041000 6C Bean, pink, seed 0.600000 1.000 1.000 0603042000 6C Bean, pinto, seed 0.600000 1.000 1.000 0601043000 6A Bean, snap, succulent 6.000000 1.000 0.010 0601043001 6A Bean, snap, succulent

- babyfood 6.000000 1.000 0.010 0603099000 6C Chickpea, flour 0.600000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 49 of 53 0603098000 6C Chickpea, seed 0.600000 1.000 1.000 0603098001 6C Chickpe a, seed

- babyfood 0.600000 1.000 1.000 0603182000 6C Guar, seed 0.600000 1.000 1.000 0603182001 6C Guar, seed

- babyfood 0.600000 1.000 1.000 0603203000 6C Lentil, seed 0.600000 1.000 1.000 0603256000 6C Pea, dry 0.600000 1.000 1.000 0603256001 6C Pea, dry

- babyfood 0.600000 1.000 1.000 0601257000 6A Pea, edible podded, succulent 6.000000 1.000 1.00 0 0603258000 6C Pea, pigeon, seed 0.600000 1.000 1.000 0602259000 6B Pea, pigeon, succulent 0.700000 1.000 1.000 0602255000 6B Pea, succulent 0.700000 1.000 1.000 0602255001 6B Pea, succulent

- babyfood 0.700000 1.000 1.000 0600347000 6 Soybean, seed 0.700000 1.000 1.000 0802148000 8BC Eggplant 4.000000 1.000 1.000 0802234000 8BC Okra 4.000000 1.000 1.000 0802270000 8B Pepper, bell 4.000000 1.000 0.050 0802271000 8B Pepper, bell, dried 4.000000 1.000 0.050 0802271001 8B Pepper, b ell, dried

- babyfood 4.000000 1.000 0.050 0802270001 8B Pepper, bell

- babyfood 4.000000 1.000 0.050 0802272000 8BC Pepper, nonbell 4.000000 1.000 0.050 0802273000 8BC Pepper, nonbell, dried 4.000000 1.000 0.050 0802272001 8BC Pepper, nonbell

- babyfood 4.000000 1.000 0.050 0801374000 8A Tomatillo 4.000000 1.000 0.050 0801375000 8A Tomato 4.000000 1.000 0.050 0801380000 8A Tomato, Tree 4.000000 1.000 0.050 0801378000 8A Tomato, dried 4.000000 14.300 0.050 0801378001 8A Tomato, dried

- babyfood 4.000000 14.300 0.050 0801379000 8A Tomato, juice 4.000000 1.500 0.050 0801376000 8A Tomato, paste 4.000000 5.400 0.050 0801376001 8A Tomato, paste

- babyfood 4.000000 5.400 0.050 0801377000 8A Tomato, puree 4.000000 3.300 0.050 0801377001 8A Tomato, puree

- babyfood 4.000000 3.300 0.050 0801375001 8A Tomato

- babyfood 4.000000 1.000 0.050 0902021000 9B Balsam pear 0.750000 1.000 1.00 0 0901075000 9A Cantaloupe 0.750000 1.000 0.010 0902088000 9B Chayote, fruit 0.750000 1.000 1.000 0902102000 9B Chinese waxgourd 0.750000 1.000 1.000 0902135000 9B Cucum ber 0.750000 1.000 0.025 0901187000 9A Honeydew melon 0.750000 1.000 0.010 0902308000 9B Pumpkin 0.750000 1.000 0.025 0902309000 9B Pumpkin, seed 0.750000 1.000 0.025 0902356000 9B Squash, summer 0.750000 1.000 0.010 0902356001 9B Squash, summer

- babyfood 0.750000 1.000 0.010 0902357000 9B Squash, winter 0.750000 1.000 0.010 0902357001 9B Squash, winter

- babyfood 0.750000 1.000 0.010 0901399000 9A Watermelon 0.750000 1.000 0.010 0901400000 9A Watermelo n, juice 0.750000 1.000 0.010 1100009000 11 Apple, dried 0.750000 8.000 0.050 1100009001 11 Apple, dried

- babyfood 0.750000 8.000 0.050 1100007000 11 Apple, fruit with peel 0.750000 1.000 0.050 1100010000 11 Apple, juice 0.750000 1.000 0.050 1100010001 11 Apple, juice

- babyfood 0.750000 1.000 0.050 1100008000 11 Apple, peeled fruit 0.750000 1.000 0.050 1100008001 11 Apple, peeled fruit

- babyfood 0.750000 1.000 0.050 1100011000 11 Apple, sauce 0.750000 1.000 0.050 1100011001 11 Apple, sauce

- babyfood 0.750000 1.000 0.050 1100129000 11 Crabapp le 0.750000 1.000 1.000 1100173500 11 Goji berry 4.000000 1.000 1.000 1100210000 11 Loquat 0.750000 1.000 1.000 1100266000 11 Pear 0.750000 1.000 0.150Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 50 of 53 1100267000 11 Pear, dried 0.750000 6.250 0.150 1100268000 11 Pear, juice 0.750000 1.000 0.150 1100268001 11 Pear, juice

- babyfood 0.750000 1.000 0.15 0 1100266001 11 Pear

- babyfood 0.750000 1.000 0.150 1100310000 11 Quince 0.750000 1.000 1.000 1202012000 12B Apricot 2.500000 1.000 0.050 1202013000 12B Apric ot, dried 2.500000 6.000 0.050 1202014000 12B Apricot, juice 2.500000 1.000 0.050 1202014001 12B Apricot, juice

- babyfood 2.500000 1.000 0.050 1202012001 12B Apricot

- babyfood 2.500000 1.000 0.050 1201090000 12A Cherry 2.500000 1.000 0.025 1201091000 12A Cherry, juice 2.500000 1.500 0.025 1201091001 12A Cherry, j uice

- babyfood 2.500000 1.500 0.025 1201090001 12A Cherry

- babyfood 2.500000 1.000 0.025 1202230000 12B Nectarine 2.500000 1.000 0.050 1202260000 12B Peach 2.500000 1.000 0.100 1202261000 12B Peach, dried 2.500000 7.000 0.100 1202261001 12B Peach, dried

- babyfood 2.500000 7.000 0.100 1202262000 12B Peach, juice 2.500000 1.000 0.100 1202262001 12B Peach, juice

- babyfood 2.500000 1.000 0.100 1202260001 12B Peach

- babyfood 2.500000 1.000 0.100 1203285000 12C Plum 0.200000 1.000 0.050 1203287000 12C Plum, p rune, dried 0.200000 5.000 0.050 1203287001 12C Plum, prune, dried

- babyfood 0.200000 5.000 0.050 1203286000 12C Plum, prune, fresh 0.200000 1.000 0.050 1203286001 12C Plum, prune, fresh

- babyfood 0.200000 1.000 0.050 1203288000 12C Plum, prune, juice 0.200000 1.400 0.050 1203288001 12C Plum, prune, juice

- babyfood 0.200000 1.400 0.050 1203285001 12C Plum

- babyfood 0.200000 1.000 0.05 0 1301055000 13A Blackberry 5.000000 1.000 0.250 1301056000 13A Blackberry, juice 5.000000 1.000 0.250 1301056001 13A Blackberry, juice

- babyfood 5.000000 1.000 0.250 1301058000 13A Boyse nberry 5.000000 1.000 0.250 1307130000 13G Cranberry 1.500000 1.000 1.000 1307131000 13G Cranberry, dried 1.500000 1.000 1.000 1307132000 13G Cranberry, juice 1.500000 1.100 1.000 1307132001 13G Cranberry, juice

- babyfood 1.500000 1.100 1.000 1307130001 13G Cranberry

- babyfood 1.500000 1.000 1.000 1304175000 13D Grape 0.750000 1.000 0.100 1304176000 13D Grape, juice 0.750000 1.000 0.100 1304176001 13D Grape, juice

- babyfood 0.750000 1.000 0.100 1304179000 13D Grape, wi ne and sherry 0.750000 1.000 0.100 1301208000 13A Loganberry 5.000000 1.000 0.250 1301320000 13A Raspberry 5.000000 1.000 0.250 1301321000 13A Raspberry, juice 5.000000 1.000 0.250 1301321001 13A Raspberry, juice

- babyfood 5.000000 1.000 0.250 1301320001 13A Raspberry

- babyfood 5.000000 1.000 0.250 1307359000 13G Strawberry 1.500000 1.000 0.450 1307360000 13G Strawberry, juice 1.500000 1.000 0.450 1307360001 13G Strawberry, juice

- babyfood 1.500000 1.000 0.450 1307359001 13G Strawberry

- babyfood 1.500000 1.000 0.450 1400003000 14 Almond 0.200000 1.000 0.050 1400004000 14 Almond, oil 0.200000 1.000 0.050 1400004001 14 Almond, oil

- babyfood 0.200000 1.000 0.050 1400003001 14 Almond

- babyfood 0.200000 1.000 0.050 1400059000 14 Brazil nut 0.200000 1.000 1.000 1400068000 14 Butternut 0.200000 1.000 1.000 1400081000 14 Cashew 0.200000 1.000 1.00 0 1400092000 14 Chestnut 0.200000 1.000 1.000 1400155000 14 Hazelnut 0.200000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 51 of 53 1400156000 14 Hazelnut, oil 0.200000 1.000 1.000 1400185000 14 Hicko ry nut 0.200000 1.000 1.000 1400213000 14 Macadamia nut 0.200000 1.000 1.000 1400269000 14 Pecan 0.200000 1.000 0.010 1400278000 14 Pine nut 0.200000 1.000 1.000 1400282000 14 Pistachio 0.200000 1.000 0.025 1400391000 14 Walnut 0.200000 1.000 0.025 1901029000 19A Basil, dried leaves 300.000000 1.000 1.000 1901029001 19A Basil, dried leaves

- babyfood 300.000000 1.000 1.000 1901028000 19A Basil, fresh leaves 30.000000 1.000 1.000 1901028001 19A Basil, fr esh leaves

- babyfood 30.000000 1.000 1.000 1901102500 19A Chive, dried leaves 300.000000 1.000 1.000 1901118000 19A Cilantro, leaves 30.000000 1.000 1.000 1901118001 19A Cilantro, leaves

- babyfood 30.000000 1.000 1.000 1901144000 19A Dillweed 30.000000 1.000 1.000 1901184000 19A Herbs, other 30.000000 1.000 1.000 1901184001 19A Herbs, other

- babyfood 30.000000 1.000 1.000 1901202000 19A Lemongrass 30.000000 1.000 1.000 1901220000 19A Marjoram 30.000000 1.000 1.000 1901220001 19A Marjoram

- babyfood 30.000000 1.000 1.000 1901249000 19A Parsley , dried leaves 300.000000 1.000 1.000 1901249001 19A Parsley, dried leaves

- babyfood 300.000000 1.000 1.000 1901334000 19A Savory 30.000000 1.000 1.000 2003128000 20C Cottonseed, oil 0.750000 1.000 1.000 2003128001 20C Cottonseed, oil

- babyfood 0.750000 1.000 1.000 3100047000 31 Beef, fat 0.100000 1.000 1.000 3100047001 31 Beef, fat

- babyfood 0.100000 1.000 1.00 0 3100048000 31 Beef, kidney 0.020000 1.000 1.000 3100049000 31 Beef, liver 0.020000 1.000 1.000 3100049001 31 Beef, liver

- babyfood 0.020000 1.000 1.000 3100044000 31 Beef, meat 0.020000 1.000 1.000 3100046000 31 Beef, meat byproducts 0.020000 1.000 1.000 3100046001 31 Beef, meat byproducts

- babyfood 0.020000 1.000 1.000 3100045000 31 Beef, meat, dried 0.020000 1.920 1.000 3100044001 31 Beef, meat

- babyfood 0.020000 1.000 1.000 3200171000 32 Goat, fat 0.100000 1.000 1.000 3200172000 32 Goat, kid ney 0.020000 1.000 1.000 3200173000 32 Goat, liver 0.020000 1.000 1.000 3200169000 32 Goat, meat 0.020000 1.000 1.000 3200170000 32 Goat, meat byproducts 0.020000 1.000 1.000 3300189000 33 Horse, meat 0.020000 1.000 1.000 3400293000 34 Pork, fat 0.100000 1.000 1.000 3400293001 34 Pork, fat

- babyfood 0.100000 1.000 1.000 3400294000 34 Pork, kidney 0.020000 1.000 1.000 3400295000 34 Pork, liver 0.020000 1.000 1.000 3400290000 34 Pork, meat 0.020000 1.000 1.000 3400292000 34 Pork, m eat byproducts 0.020000 1.000 1.000 3400292001 34 Pork, meat byproducts

- babyfood 0.020000 1.000 1.000 3400290001 34 Pork, meat

- babyfood 0.020000 1.000 1.000 3400291000 34 Pork, skin 0.100000 1.000 1.000 3500341000 35 Sheep, fat 0.100000 1.000 1.000 3500341001 35 Sheep, fat

- babyfood 0.100000 1.000 1.000 3500342000 35 Sheep, kidney 0.020000 1.000 1.00 0 3500343000 35 Sheep, liver 0.020000 1.000 1.000 3500339000 35 Sheep, meat 0.020000 1.000 1.000 3500340000 35 Sheep, meat byproducts 0.020000 1.000 1.000 3500339001 35 Sheep , meat
- babyfood 0.020000 1.000 1.000 3600222000 36 Milk, fat 0.020000 1.000 1.000 3600222001 36 Milk, fat

- baby food/infant formu 0.020000 1.000 1.000 3600223000 36 Milk, nonfat solids 0.020000 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 52 of 53 3600223001 36 Milk, nonfat solids

- baby food/in 0.020000 1.000 1.000 3600225001 36 Milk, sugar (lactose)

- baby food/ 0.020000 1.000 1.000 3600224000 36 Milk, water 0.020000 1.000 1.000 3600224001 36 Milk, water

- babyfood/infant form 0.020000 1.000 1.000 3800221000 38 Meat, game 0.020000 1.000 1.000 3900312000 39 Rabbit, m eat 0.020000 1.000 1.000 8601000000 86A Water, direct, all sources 0.011200 1.000 1.000 8602000000 86B Water, indirect, all sources 0.011200 1.000 1.000Bifenazate (000586) Dietary Exposure and Risk Assessment DP# 388801

Page 53 of 53 

### Attachment 10. Bifenazate Chronic Results.

US EPA Ver. 3.16, 03

- 08

- d DEEM
- FCID Chronic analysis for BIFENAZATE NHANES 2003

- 2008 2

- day Residue file name: J: \ Work Files \ $ Bifenazate \ $$New \ DEEM \ 03_25_2014_Tolerance levels_Bifena zate_chronic.R08 Adjustment factor #2 used. Analysis Date 03

- 25

- 2014/14:54:33 Residue file dated: 03

- 25

- 2014/14:52:49 Reference dose (RfD, Chronic) = .01 mg/kg bw/day COMMENT 1: aPAD for General Pop

- 6 mg/kg/day; aPAD for Females 13 to 49 years

- 0.1 mg/kg/day; cPAD

- 0.01 mg/kg/day

=============================================================================== Total exposure by population subgroup

-------------------------------- ----------------------------------------------- Total Exposure

----------------------------------- Population mg/kg Percent of Subgroup body wt/day Rfd

-------------------------------------- ------------- ---------------- Total US Population 0.002360 23.6% Hispanic 0.003420 34.2% Non
- Hisp

- White 0.002143 21.4% Non
- Hisp

- Black 0.002101 21.0% Non
- Hisp

- Other 0.003131 31.3% Nursing Infants 0.002897 29.0% Non
- Nursing Infants 0.004077 40.8% Female 13+ PREG 0.002598 26.0% Children 1

- 6 0.006035 60.3% Children 7

- 12 0.002852 28.5% Male 13

- 19 0.001867 18.7% Female 13

- 19/NP 0.001852 18.5% Male 20+ 0.002009 20.1% Female 20+/NP 0.001828 18.3% Seniors 55+ 0.001652 16.5% All Infants 0.003713 37.1% Female 13

- 50 0.001941 19.4% Children 1

- 2 0. 007438 74.4% Children 3

- 5 0.005635 56.4% Children 6

- 12 0.003053 30.5% Youth 13

- 19 0.001858 18.6% Adults 20

- 49 0.002106 21.1% Adults 50

- 99 0.001681 16.8% Female 13

- 49 0.001950 19.5%