| **Segment, Geographic and Other Revenue Information - Revenues by Geographic Area (Detail) - USD ($) $ in Millions**                                                                                                                                                                                                                                                            | 12 Months Ended |
|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|-----------------|
||
| **Revenues from External Customers and Long-Lived Assets [Line Items]**                                                                                                                                                                                                                                                                                                         |                 |   |   |   |
| Revenues:                                                                                                                                                                                                                                                                                                                                                                       | [1]             | $ 58,496 | $ 100,330 | $ 81,288 |
| United States [Member]                                                                                                                                                                                                                                                                                                                                                          |                 |   |   |   |
| **Revenues from External Customers and Long-Lived Assets [Line Items]**                                                                                                                                                                                                                                                                                                         |                 |   |   |   |
| Revenues:                                                                                                                                                                                                                                                                                                                                                                       |                 | 27,088 | 42,473 | 29,746 |
| Developed Europe [Member]                                                                                                                                                                                                                                                                                                                                                       |                 |   |   |   |
| **Revenues from External Customers and Long-Lived Assets [Line Items]**                                                                                                                                                                                                                                                                                                         |                 |   |   |   |
| Revenues:                                                                                                                                                                                                                                                                                                                                                                       |                 | 11,650 | 21,982 | 18,336 |
| Developed Rest of World [Member]                                                                                                                                                                                                                                                                                                                                                |                 |   |   |   |
| **Revenues from External Customers and Long-Lived Assets [Line Items]**                                                                                                                                                                                                                                                                                                         |                 |   |   |   |
| Revenues:                                                                                                                                                                                                                                                                                                                                                                       |                 | 7,761 | 15,778 | 12,506 |
| Emerging Markets [Member]                                                                                                                                                                                                                                                                                                                                                       |                 |   |   |   |
| **Revenues from External Customers and Long-Lived Assets [Line Items]**                                                                                                                                                                                                                                                                                                         |                 |   |   |   |
| Revenues:                                                                                                                                                                                                                                                                                                                                                                       |                 | $ 11,996 | $ 20,097 | $ 20,701 |
|                                                                                                                                                                                                                                                                                                                                                                                 |
| [1]Earnings = Income from continuing operations before provision/(benefit) for taxes on income. Biopharma’s revenues and earnings in 2023 reflect a non-cash revenue reversal of $3.5 billion (see Note 17C). Biopharma’s earnings also include dividend income from our investment in ViiV of $265 million in 2023, $314 million in 2022 and $166 million in 2021. |

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Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).
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