| **Segment, Geographic and Other Revenue Information - Narrative (Detail) treatmentCourse in Millions, $ in Millions**               | 12 Months Ended |
|-------------------------------------------------------------------------------------------------------------------------------------|-----------------|
||
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Number of operating segments | operatingSegment                                                                                     | 2               |   |   |
| Total assets                                                                                                                        | $ 226,501.0     | $ 197,205.0 |   |
| Deferred revenues, current                                                                                                          | 2,700.0         | 2,520.0 |   |
| Comirnaty [Member]                                                                                                                  |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Remaining performance obligation                                                                                                    | 6,000.0         |   |   |
| Paxlovid [Member]                                                                                                                   |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Remaining performance obligation                                                                                                    | $ 3,400.0       |   |   |
| Paxlovid, EUA-Labeled [Member]                                                                                                      |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Estimated government emergency use authorization inventory to be returned to company, number of treatment courses | treatmentCourse | 6.5             |   |   |
| Reversal of revenue                                                                                                                 | $ 3,500.0       |   |   |
| Paxlovid, NDA-Labeled, Commercial Supply [Member]                                                                                   |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Supply commitment, minimum amount committed, number of treatment courses | treatmentCourse                                          | 6.5             |   |   |
| Paxlovid, NDA-Labeled, U.S. Strategic National Stockpile [Member]                                                                   |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Supply commitment, minimum amount committed, number of treatment courses | treatmentCourse                                          | 1.0             |   |   |
| Paxlovid, NDA-Labeled [Member]                                                                                                      |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Supply commitment, minimum amount committed, number of treatment courses | treatmentCourse                                          | 7.5             |   |   |
| Government and Government Sponsored [Member] | Comirnaty [Member]                                                                   |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Deferred revenues                                                                                                                   | $ 1,700.0       | 2,500.0 |   |
| Deferred revenues, current                                                                                                          | 1,100.0         | 2,400.0 |   |
| Deferred revenues, noncurrent                                                                                                       | 552.0           | $ 77.0 |   |
| Deferred revenue, revenue recognized                                                                                                | 2,200.0         |   |   |
| Government and Government Sponsored [Member] | Paxlovid [Member]                                                                    |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Deferred revenues                                                                                                                   | 3,400.0         |   |   |
| Deferred revenues, current                                                                                                          | 1,500.0         |   |   |
| Deferred revenues, noncurrent                                                                                                       | $ 1,900.0       |   |   |
| Geographic Concentration Risk [Member] | Revenue [Member] | Outside United States [Member]                                          |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Number of countries with revenue exceeding $500 million | country                                                                   | 14              | 24 | 21 |
| Geographic Concentration Risk [Member] | Revenue [Member] | U.S. [Member]                                                           |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Concentration risk, percentage                                                                                                      | 10.00%          | 10.00% | 10.00% |
| Geographic Concentration Risk [Member] | Revenue [Member] | Japan [Member]                                                          |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Concentration risk, percentage                                                                                                      | 6.00%           | 8.00% | 9.00% |
| Customer Concentration Risk [Member] | Accounts Receivable [Member] | Three Largest U.S. Wholesaler Customers [Member]              |            |   |   |
| **Segment Reporting Information [Line Items]**                                                                                      |            |   |   |
| Concentration risk, percentage                                                                                                      | 44.00%          | 32.00% |   |

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| - Definition
Sum of the carrying amounts as of the balance sheet date of all assets that are recognized. Assets are probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.
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| - Definition
For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.
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| - Definition
Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.
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Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable, classified as current.
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Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable, classified as noncurrent.
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Amount of revenue recognized that was previously included in balance of obligation to transfer good or service to customer for which consideration from customer has been received or is due.
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Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues.
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Amount of transaction price allocated to performance obligation that has not been recognized as revenue.
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