# DRAFT

Testing of Certain High Production Volume Chemicals ; Fourth Group of Chemicals ( Exposure Findings Supporting Information )

U.S. Environmental Protection Agency Office of Pollution Prevention and Toxics Economics, Exposure and Technology Division

May 2011i 

# Table of Contents PREFACE 1.0 D ATA S OURCE D ESCRIPTIONS ................................ ................................ ................................ ........... 3 2.0 S UMMARY OF H PV4 C HEMICALS AND F IND INGS ................................ ................................ ............... 4ii 

# P reface This findings document was prepared to support EPA’s Proposed TSCA Section 4 Test Rule for Certain High Production Volume Chemicals ; Fourth Group of Chemicals . Prior to promulgating a test rule under section 4 of the Toxic Substances Control Act (TSCA), 15 U.S.C. §§2601 et seq , EPA is required to make certain findings identified in section 4(a) of TSCA relating to the chemical’s risk and potential exposure, the sufficiency of data to allow EPA to determine the human health or environmental effects of the chemical, and the need to conduct testing. Under TSCA section 4(a)(1)(B), EPA must make the following findings to support a test rule based on concerns for exposure: (1) that a chemical substance is or will be produced in substantial quantities and that it enters or may reasonably be anticipated to enter the environment in substantial quantities and/or that there is or may be substantial and/or significant human exposure to such substance; (2) that there are insufficient data and experience upon which the effects of the manufacture, distribution in commerce, processing, use or disposal of such substance or mixture or of any combinatio n of such activities on health or the environment can reasonably be determined or predicted; and (3) that testing of the substance or mixture with respect to such effects is necessary to develop such data. The criteria and standards used by EPA for evaluating the terms “substantial production,” “substantial release,” and “substantial or significant human exposure” as used in TSCA section 4(a)(1)(B)(i) are explained in EPA’s Final Statement of Policy; Criteria for Evaluating Substantial Production, Substantial Release, and Substantial or Significant Human Exposure set forth at 58 FR 28736 (May 14, 1993) (hereinafter referred to as the “B Policy”). This document provides a detailed discussion of EPA’s evaluation of each of the chemical substance s identified in the proposed test rule to determine that preliminary TSCA section 4(a)(1)(B) findings concerning “substantial production,” “substantial release,” and “substantial or significant human exposure” can be made.3

1.0 D ATA S OURCE D ESCRIPTIONS 

### TSCA In ventory Update Reporting Rule : In 1986, EPA promulgated the Inventory Update Reporting (IUR) regulations, under TSCA section 8(a), to facilitate the periodic updating of the TSCA Inventory

database and to otherwise support activities associated with implem enting TSCA. As originall y promulgated, the IUR required chemical manufacturers (including importers) to report to EPA every 4 ye ars the identity of chemical substances manufactured (including imported) annually in quantities of 10,000 pounds or more at ea ch plant site they owned or controlled. In 2003 , EPA adjusted the universe of chemicals and plant sites that are required to report, and the ty pe of information reported. In 2005, EPA changed the reporting frequency to once every

5 years, revised the manner in which amounts of a chemical substance manufactured or imported must be reported, and changed the submission period for reporting after 2006. To protect the claims of confidential business information (CBI) asserted by some IUR submitters on the amount of the chemical substance manufactured (including imported) at a specific site, all production volumes reported by IUR submitters (i.e., CBI and non - CBI) for each chemical are combined by EPA for an aggregate total. Confidential business information claims are further protected by using eight ranges to identify the total for any specific chemical and then making available to the public the range that corresponds to the aggregate production volume. Publicly available information from the 1986, 1990, 1994, 1998, and 2002 (and 2006) IUR reporting cycles are available on line at: http://www.epa.gov/oppt/iur/index.htm The Toxics Release Inventory (TRI) contains information about releases of certain chemicals and management of wa stes at a wide variety of sources, including manufacturing operations, certain service businesses, and federal facilities. Publicly - available information from the 2008 TRI reporting cycle is available on - line at: http://www.epa.gov/triexplorer/ The National Library of Medicine Household Products Database provides information on the chemical ingredients and their percentage in specific brands of household products. Information in the database is from a variety of publicly available sources including brand - specific labels and Material Safety Data Sheets wh en available from manufacturers and manufacturers' web sites. Publicly - available information from the database is available on line at: http://householdproducts.nlm.nih.gov/4 2.0 S UMMARY OF HPV4 C HEMICALS AND F INDINGS Table 2 - 1 below

presents a summary of the high production volume (HPV) chemicals and data collected to support an exposure -based finding. Table 2 - 2 pres ents a chemical -by - chemical explanation of the supporting findings information. Table 2 - 1 Summary of Data Se arched for Exposure Based Findings

CAS# Chemical Name 2006 IUR Production Volume [Million lbs] PAIR

Production Volume [Million lbs] 2006 IUR -

Substantial Human Exposure (>1,000 Work ers) Met PAIR -

Substantial Human Exposure (>1,000 Work ers) Met NLM Household

Chemicals Database Non - CBI 2006

IUR Commercial/ Consumer Code Description PAIR -

Substantial Human Exposure (Consumer Use Indicated) PAIR -

Substantial Release Criteria (>1 million lbs) Met 200 8 TRI

Data(Total On and Off - site Disposal or Other Releases, lbs) Meet

Exposure Based Criteria for Work ers Meet Exposure Based Criteria for Consumers Meet

Exposure Based Criteria for Release 1 56 - 40 - 6 Glycine 1 < 10 - Yes - 25 personal care products C20 - Other - - - Yes Yes No 2 67 - 72 - 1 Ethane, 1,1,1,2,2,2 -

hexachloro 1 < 10 - Yes - - - - - 1,031 lbs released onsite; 288,418 lbs released offsite; Yes No No 3 78 - 00 - 2 Plumbane, tetraethyl - 1 < 10 - No - - C10 - Lubricants, greases and fuel additives - - - No Yes No 4 95 - 14 - 7 1H - Benzotriazole 1 < 10 - No - 4 inside - the - home products C10 - Lubricants,

greases, and fuel additives; C11 - Metal products; C20 - Other - - - No Yes No 5 118 - 48 - 9 2H - 3,1 - Benzoxazine 2,4(1H) - dione 10 < 50 - No - - C2 - Agricultural products (non pesticidal); C20 - Other - - - No Yes No 6 128 - 44 - 9 1,2 - Benzisothiazol 3(2H) - one, 1,1 - dioxide, sodium salt (1:1) 1 < 10 - No - 132 personal care products C20 - Other - - - No Yes No 7 928 - 72 - 3 Glycine, N -

(carboxymethyl) - , sodium salt (1:2) 500 < 1,000 CBI Yes CBI - - CBI CBI - Yes CBI CBITable 2 - 1 (Continued)

5 CAS# Chemical Name 2006 IUR Production Volume [Million lbs] PAIR

Production Volume [Million lbs] 2006 IUR -

Substantial Human Exposure (>1,000 Work ers) Met PAIR -

Substantial Human Exposure (>1,000 Work ers) Met NLM Household

Chemicals Database Non - CBI 2006

IUR Commercial/ Consumer Code Description PAIR -

Substantial Human Exposure (Consumer Use Indicated) PAIR -

Substantial Release Criteria (>1 million lbs) Met 200 8 TRI

Data(Total On and Off - site Disposal or Other Releases, lbs) Meet

Exposure Based Criteria for Work ers Meet Exposure Based Criteria for Consumers Meet

Exposure Based Criteria for Release 8 1809 - 19 - 4 Phosphonic acid, dibutyl

ester 1 < 10 - Yes - - CBI - - - Yes CBI No 9 25377 - 73 - 5 2,5 - Furandione, 3 -

(dodecen - 1 - yl)dihydro 1 < 10 - No - - C20 - Other - - - No Yes No 10 26544 - 38 - 7 2,5 - Furandione, dihydro 3 - (tetrapropenyl) - 1 < 10 - No - - C10 - Lubricants, greases and fuel additives; C12 - Paints and coatings; NRO - - - No Yes No 11 27859 - 58 - 1 Butanedioic acid, 2 -

(tetrapropenyl) - 1 < 10 - Yes - - C10 - Lubricants, greases and fuel additives - - - Yes Yes No 12 28777 - 98 - 2 2,5 - Furandione, dihydro 3 - (octadecen - 1 - yl) - 10 < 50 - No - - C13 - Paper Products - - - No Yes No 13 29385 - 43 - 1 1H - Benzotriazole, 6 (or

7 ) - methyl 1 < 10 - No - - C10 - Lubricants, greases and fuel additives - - - No Yes No 14 32072 - 96 - 1 2,5 - Furandione, 3 -

(hexadecen - 1 - yl)dihydro 50 < 100 - Yes - - C13 - Paper products - - - Yes Yes No 15 61789 - 73 - 9 Quaternary ammonium

compounds, benzylbis(hydrogenated tallow alkyl)methyl, chlorides 1 < 10 - No - - CBI - - - No CBI No 16 64665 - 57 - 2 1H - Benzotriazole, 6 (or

7 ) - methyl - , sodium salt 1 < 10 - No - - C20 - Other - - - No Yes No 17 68131 - 13 - 5 Naphthenic acids,

reaction products with diethylenetriamine 1 < 10 - Yes - 1 product used inside the home, in arts & crafts, or in home offices - - - Yes Yes No 18 68153 - 60 - 6 Fatty acids, tall - oil,

reaction products with diethylenetriamine, acetates 1 < 10 CBI Yes CBI - - CBI CBI - Yes CBI CBITable 2 - 1 (Continued)

6 CAS# Chemical Name 2006 IUR Production Volume [Million lbs] PAIR

Production Volume [Million lbs] 2006 IUR -

Substantial Human Exposure (>1,000 Work ers) Met PAIR -

Substantial Human Exposure (>1,000 Work ers) Met NLM Household

Chemicals Database Non - CBI 2006

IUR Commercial/ Consumer Code Description PAIR -

Substantial Human Exposure (Consumer Use Indicated) PAIR -

Substantial Release Criteria (>1 million lbs) Met 200 8 TRI

Data(Total On and Off - site Disposal or Other Releases, lbs) Meet

Exposure Based Criteria for Work ers Meet Exposure Based Criteria for Consumers Meet

Exposure Based Criteria for Release 19 68424 - 85 - 1 Quaternary ammonium

compounds, benzyl - C12 - 16 - alkyldimethyl,chlorides 1 < 10 - Yes - 3 auto products, 28 home products, 2 personal care products C20 - Other - - - Yes Yes No 20 68442 - 77 - 3 2 - Butenediamide, (2E) - ,

N1,N4 -bis[2 - (4,5 - dihydro - 2 - nortall - oil alkyl - 1H - imidazol - 1 - yl)ethyl] derivs. 1 < 10 CBI Yes CBI - - CBI CBI - Yes CBI CBI

21 68607 - 28 - 3 Quaternary ammonium

compounds, (oxydi - 2,1 - ethanediyl)bis[coco alkyldimethyl, dichlorides 1 < 10 - Yes - - C20 - Other - - - Yes Yes No 22 68909 - 18 - 2 Py

ridinium, 1 - (phenylmethyl) - , Et Me derivs., chlorides 1 < 10 - Yes - - C20 - Other - - - Yes Yes No 23 69834 - 17 - 9 Benzene, decylphenoxy - 1 < 10 - No - - C17 - Soaps and detergents - - - No Yes No * “ - “ indicates no information available. ** “CBI” indicates information is available; however it is claimed as CBI. This information is provided in a separate CBI attachment.Table 2 - 2 Chemical- by - Chemical Explanation of Findings CAS# Chemical Name Summary of Findings

1 56 - 40 - 6 Glycine The total number of potentially exposed workers is likely to exceed 1,000 based on reported IUR data. The NLM database indicates this chemical is used as an ingredient in 25 personal care products . Additionally, the IUR commercial/consumer product category C20

– Other ( chemicals contained in commercial and consumer products not elsewhere classified

) was reported for this chemical. This indicates that this chemical is present in an unknown number of commercial and consumer products that may potentially have a high number of exposures. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 1 0 million lb)

- Total workers exceeding 1,000 based on IUR data

- Consumers potentially exceeding 10,000 people based on NLM data and IUR commercial/consumer product category (C20) 2 67 - 72 - 1 Ethane, 1,1,1,2,2,2 -

hexachloro The total number of potentially exposed workers is likely to exceed 1,000 based on reported IUR data. This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Total workers exceeding 1,000 based on IUR data

3 78 - 00 - 2 Plumbane, tetraethyl The IUR commercial/consumer product category C10

– Lubricants, greases, and fuel additives was reported for this chemical. Chemicals reporting in this category are added to gasoline, kerosene, and distillate fuel oil after refining . They are additives in products used to enhance or clean combustion devices; it is expected that these products will be widely used by commercial workers and consumers and hence, may likely exceed 10,000 people. Based on this information, this chemical would meet the exposure b ased findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C 1 0)CAS# Chemical Name Summary of Findings

4 95 - 14 - 7 1H - Benzotriazole The NLM database indicates this chemical is used as an ingredient in 4 inside - the - home products . Additionally, the IUR commercial/consumer product categories C10

– Lubricants, gre ases, and fuel additives, C11

– Metal products, and C20

– Other were reported for this chemical. Chemicals reporting in C10 are added to gasoline, kerosene, and distillate fuel oil after refining . Chemicals reporting in C11 are contained in metals and me tallic substances contained in metal products for commercial and consumer use. Chemicals reporting in C20 are contained in commercial and consumer products not elsewhere specified. This indicates that this chemical is present in an unknown number of comme rcial and consumer products that may potentially have a high number of exposures. Based on these reporting categories, it is expected that this chemical will be contained in products that are widely used by commercial workers and consumers (including children) and hence, may likely exceed 10,000 people. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Consumers potentially exceeding 10,000 people based on NLM data and IUR commercial/consumer product categories (C 10, C11, and C 20)

5 118 - 48 - 9 2H - 3,1 - Benzoxazine 2,4(1H) - dione The IUR commercial/consumer product category C2

– Agricultural products (non -pesticidal) and C20

– Other ( chemicals contained in commercial and consumer products not elsewhere classified

) were reported for this chemical. Chemicals reporting in C2 are used to incre ase the productivity and quality of farm products. An e xample for this chemical wo uld be use as a soil conditioner. Chemicals reporting in C20 are present in an unknown number of commercial and consumer products that may potentially have a high number of exposures. It is possible that products containing this chemical are used widely by more than 10,000 commercial workers and consumers. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (10 million - 50 million lb)

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C2, C20)CAS# Chemical Name Summary of Findings

6 128 - 44 - 9 1,2 - Benzisothiazol - 3(2H) -

one, 1,1 - dioxide, sodium salt (1:1) The NLM database indicates this chemical is used as an ingredient in 132 personal care products. Additionally, the IUR commercial/consumer product category C20

– Other ( chemicals conta ined in commercial and consumer products not elsewhere classified

) was reported for this chemical. This indicates that this chemical is present in an unknown number of commercial and consumer products that may potentially have a high number of exposures. B ased on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Consumers potentially exceeding 10,000 people based on NLM data and IUR commercial/consumer product category (C20) 7 928 - 72 - 3 Glycine, N -

(carboxymethyl) - , sodium salt (1:2) The total number of potentially exposed workers is likely to exceed 1,000 based on reported IUR data. This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Total workers exceeding 1,000 based on IUR data

8 1809 - 19 - 4 Phosphonic acid, dibutyl

ester The total number of potentially exposed workers is likely to exceed 1,000 based on reported IUR data. The IUR commercial/consumer use information is claimed CBI for this chemical. The types of products containing this chemical are unknown but may be widely used by commercial workers and consumers and hence, may likely exceed 10,000 people. Based on this information, this chemical would meet the exposure based findings criteria of "substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Total workers exceeding 1,000 based on IUR data

- Consumers potentially exceeding 10,000 people based on an IUR commercial/consumer product category who se identity is CBI .CAS# Chemical Name Summary of Findings

9 25377 - 73 - 5 2,5 - Furandione, 3 - (dodecen 1 - yl)dihydro T he IUR commercial/consumer product category C20

– Other ( chemicals contained in commercial and consumer products not elsewhere classified

) was reported for this chemical. This indicates that this chemical is present in an unknown number of commercial and c onsumer products that may potentially have a high number of exposures. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings crite ria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C20)

10 26544 - 38 - 7 2,5 - Furandione, dihydro - 3 -

(tetrapropenyl) - The IUR commercial/consumer product categories C10

– Lubricants, greases, and fuel additives, C12

– Paints and coatings, and NRO

– Not readily obtainable were reported for this chemical. Chemicals reporting in C10 are added to gasoline, kerosene, and distillate fuel oil after refining . Chemicals reporting in C12 are contained in commercial and consumer paints, including artists’ paints, varnishes, lacquers, enamels and shellac, paint and varnish removers and cleaners. Chemicals reporting in NRO are potentially present in commercial or consumer products although such information is not available. Based on these reporting categories, it is expected that this chemical will be contained in products that are widely used by commercial workers and consumers and hence, may likely exceed 10,000 people. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C 10, 12, NRO )CAS# Chemical Name Summary of Findings

11 27859 - 58 - 1 Butanedioic acid, 2 -

(tetrapropenyl) - The total number of potentially exposed workers is likely to exceed 1,000 based on reported IUR data. T he IUR commercial/consumer product category C10

– Lubricants, greases, and fuel additives was reported for this chemical. Chemicals reporting in this category are added to gasoline, kerosene, and distillate fuel oil after refining . They are additives in products used to enhance or clean combustion devices; it is expected that these products will be widely used by commercial workers and consumers and he nce, may likely exceed 10,000 people. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Total workers exceeding 1,000 based on IUR data

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C 10 )

12 28777 - 98 - 2 2,5 - Furandione, dihydro - 3 -

(octadecen - 1 - yl) - The IUR commercial/consumer product category C13

– Paper products was reported for this chemical. Chemicals reporting in this category are contained in commercial and consumer paper products. It is expected that paper products are widely used by commercial workers and consumers which may exceed 10,000 people. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria ba sed on:

- 2006 IUR Production Volume Range (1 0 mi llion - 5 0 million lb)

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C 13 )

13 29385 - 43 - 1 1H - Benzotriazole, 6 (or 7 ) -

methyl T he IUR commercial/consumer product category C10

– Lubricants, greases, and fuel additives was reported for this chemical. Chemicals reporting in this category are added to gasoline, kerosene, and distillate fuel oil after refining . They are additives in p roducts used to enhance or clean combustion devices; it is expected that these products will be widely used by commercial workers and consumers and hence, may likely exceed 10,000 people. Based on this information, this chemical would meet the exposure ba sed findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C 10 )CAS# Chemical Name Summary of Findings

14 32072 - 96 - 1 2,5 - Furandione, 3 -

(hexadecen - 1 - yl)dihydro The total number of potentially exposed workers is likely to exceed 1,000 based on reported IUR data. T he IUR commercial/consumer product category C13

– Paper products was reported for this chemical. Chemicals reporting in this category are contained in commercial and consumer paper products. It is expected that paper products are widely used by commercial workers and consumers which may exceed 10,000 people. Based on this information, this chemical would meet the expos ure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on :

- 2006 IUR Production Volume Range ( 50 mi llion - 10 0 million lb)

- Total workers exceeding 1,000 based on IUR data

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C 13 ) 1 5 61789 - 73 - 9 Quaternary ammonium

compounds, benzylbis(hydrogenated tallow alkyl)methyl, chlorides This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Consumers potentially exceeding 10,000 people based on an IUR commercial/consumer product category who se identity is CBI .

1 6 64665 - 57 - 2 1H - Benzotriazole, 6 (or 7 ) -

methyl - , sodium salt The IUR commercial/consumer product category C20

– Other ( chemicals contained in commercial and consumer products not elsewhere classified

) was reported for this chemical. This indicates that this chemical is present in an unknown number of commercial and consumer products that may potentially have a high number of exposures. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Consumers potentially exceeding 10,000 people b ased on IUR commercial/consumer product category (C20)

1 7 68131 - 13 - 5 Naphthenic acids, reaction

products with diethylenetriamine The total number of potentially exposed workers exceeds 1,000 workers based on IUR data. The NLM database indicates this chemical is used as an ingredient in 1 product that is used inside the home, in arts and crafts, or in home offices. This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Total workers exceeding 1,000 based on IUR data

- Consumers potentially exceeding 10,000 people based on NLM dataCAS# Chemical Name Summary of Findings

1 8 68153 - 60 - 6 Fatty acids, tall - oil, reaction

products with diethylenetriamine, acetates The total number of potentially exposed workers exc eeds 1,000 workers based on IUR data. This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Total workers exceeding 1,000 based on IUR data

19 68424 - 85 - 1 Quaternary ammonium

compounds, benzyl - C12 - 16 - alkyldimethyl,chlorides The total number of potentially exposed workers exceeds 1,000 workers based on IUR data. The NLM database indicates this chemical is used as an ingredient in 3 automotive products, 28 home products, and 2 personal care products. Additionally, the IUR commercial/consumer product category C20

– Other ( chemicals contained in commercial and consumer products not elsewhere classified

) was reported for this chemical. This indicates that this chemical is present in an unknown number of commercial and consumer products that may potentially have a high number of exposures. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This c hemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Total workers exceeding 1,000 based on IUR data

- Consumers potentially exceeding 10,000 people based on NLM data and IUR commercial/con sumer product category (C20)

20 68442 - 77 - 3 2 - Butenediamide, (2E) - ,

N1,N4 -bis[2 - (4,5 - dihydro 2 - nortall - oil alkyl - 1H imidazol - 1 - yl)ethyl] derivs. The total number of potentially exposed workers exceeds 1,000 workers based on IUR data. This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Total workers exceeding 1,000 based on IUR dataCAS# Chemical Name Summary of Findings

21 68607 - 28 - 3 Quaternary ammonium

compounds, (oxydi - 2,1 - ethanediyl)bis[coco alkyldimethyl, dichlorides The total number of potentially exposed workers exceeds 1,000 workers based on IUR data. The IUR commercial/consumer product category C20

– Other ( chemicals contained in commercial and consumer products not elsewhere classified

) was reported f

or this chemical. This indicates that this chemical is present in an unknown number of commercial and consumer products that may potentially have a high number of exposures. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Total workers exceeding 1,000 based on IUR data

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C20)

22 68909 - 18 - 2 Py

ridinium, 1 - (phenylmethyl) - , Et Me derivs., chlorides The total number of potentially exposed workers exceeds 1,000 workers based on IUR data. T he IUR commercial/consumer product category C20

– Other ( chemicals contained in commercial and consumer products not elsewhere classified

) was reported for this chemical. This indicates that this chemical is present in an unknown number of commercial and c onsumer products that may potentially have a high number of exposures. Based on this information, this chemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Total workers exceeding 1,000 based on IUR data

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C20)

23 69834 - 17 - 9 Benzene, decylphenoxy The IUR commercial/consumer product category C17

– Soaps and detergents was reported for this chemical. Chemicals reporting in this category are contained in liquid, granulated, caked, and flaked washing detergents and personal soap s, dishwashing compounds, presoaks and scouring compounds for commercial and consumer use. It is expected that these products are widely used by commercial workers, consumers, and children, which may exceed 10,000 people. Based on this information, this c hemical would meet the exposure based findings criteria of “ substantial or significant human exposure.” This chemical met exposure based findings criteria based on:

- 2006 IUR Production Volume Range (1 million - 10 million lb)

- Consumers potentially exceeding 10,000 people based on IUR commercial/consumer product category (C17)