| ☒ | QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIESEXCHANGE ACT OF 1934 |
|----------|----------------------------------------------------------------------------------------|

| ☐ | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIESEXCHANGE ACT OF 1934 |
|----------|-----------------------------------------------------------------------------------------|

| DELAWARE                                                      |   | 93-0987903                          |
|---------------------------------------------------------------|--------|-------------------------------------|
| (STATE OR OTHER JURISDICTION OFINCORPORATION OR ORGANIZATION) |   | (I.R.S. EMPLOYERIDENTIFICATION NO.) |

| Largeaccelerated filer       | ☐                          | Acceleratedfiler         | ☐ |
|------------------------------|-----------------------------------|--------------------------|----------|
| Non-acceleratedfiler         | ☐                | Smallerreporting company | ☒ |
| Emerginggrowth company  | ☐      |                     |     |

|          |                                                                                                                           |                     |
|---------------|--------------------------------------------------------------------------------------------------------------------------------|--------------------------|
| ExhibitNo.    | Exhibit Name                                                                                                                   | Filedwith this Form 10-Q |
| 10.1†* | Asset Purchase and License Agreement with Boehringer IngelheimInternational GmbH                                               |  X                  |
| 31.1*         | Certificationof Chief Executive Officer pursuant to Section 302 of theSarbanes-Oxley Act of 2002                          |  X                  |
| 31.2*         | Certificationof Chief Financial Officer pursuant to Section 302 of theSarbanes-Oxley Act of 2002                          |  X                  |
| 32.1*         | Certificationpursuant to 18 U.S.C. Section 1350, as adopted pursuant toSection 906 of the Sarbanes-Oxley Act of 2002 |  X                  |
| 101*          | Interactivedata file                                                                                                           |                     |

|                |                              |                                                                                                          |
|---------------------|-----------------------------------|---------------------------------------------------------------------------------------------------------------|
| Date:March 29, 2019 | MABVAXTHERAPEUTICS HOLDINGS, INC. |
|                |                              |                                                                                                          |
|                | By:                               | /s/ J. DavidHansen                                                                                            |
|                |                              | J.David Hansen                                                                                                |
|                |                              | Presidentand Chief Executive Officer(PrincipalExecutive Officer authorizedto signon behalf of the registrant) |

|   |   |                                                                                                           |
|--------|--------|----------------------------------------------------------------------------------------------------------------|
|   |   |                                                                                                           |
|   | By:    | /s/ Gregory P.Hanson                                                                                           |
|   |   | GregoryP. Hanson                                                                                               |
|   |   | ChiefFinancial Officer(PrincipalFinancial and Accounting Officerauthorizedto sign on behalf of the registrant) |