1

OFFICE OF

CHEMICAL SAFETY AND

POLLUTION PREVENTION

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON D.C., 20460

PC Code: 128940

Barcodes: D416293, D416294

Chemical: Flutriafol

April 3, 2014

MEMORANDUM

Subject: Drinking water assessment for proposed new uses (R190, PP# 3F8199) of

Flutriafol on leafy vegetables (Group 4), brassica (cole) leafy vegetables 

(Group 5), grain sorghum, and cotton and (R190, PP# 3F8174) for 

cucurbit vegetables, fruiting vegetables, strawberries, tree nuts, and wheat

uses.

TO: Tamue Gibson, Risk Manager Reviewer

Cynthia Giles-Parker, Branch Chief

Fungicide Branch

Registration Division (7505P)

FROM: James K. Wolf, Ph.D., Environmental Scientist

Environmental Risk Branch 3

REVIEWED BY: James A. Hetrick, Ph.D., Senior Science Advisor

Rosanna Louie-Juzwiak, RAPL

Environmental Risk Branch 3

THROUGH: Dana Spatz, Branch Chief

Environmental Risk Branch 3

Environmental Fate and Effects Division (7507P)

This memo presents a Tier 1 drinking water assessment for the new uses proposed by the 

registrant in two separate tolerance petitions 3F38199 and 3F8173 requests. The first petition is

for Flutriafol Technical (EPA Reg. No. 4787-55), TOPGUARD®Fungicide (EPA Reg. No. 

67760-751), Flutriafol ®250 g/L Fungicide (EPA Reg No. 67760-1202) and Flutriafol 500 g/L 

 

1 Topguard Fungicide 67760-75 Proposed Label 9 5 2013 for Tol Petition No. 3F8199.

2

Flutriafol 250 g/L SC 67760 129 Proposed Label 9 5 2013 for Tol Petition No. 3F8199.
2

SC Fungicide (67760-Flutriafol3). The uses proposed with these label amendments are to add 

leafy vegetables (Group 4), brassica (cole) leafy vegetables (Group 5), grain sorghum, and cotton 

uses. The second tolerance petition requests to add the following crop groupings; Cucurbit 

Vegetables, Fruiting Vegetables, Strawberries, Tree Nuts, and Wheat to the following labels 

(EPA Reg. No. 67760-754) Flutriafol®250 g/L Fungicide (EPA Reg. No. 67760-

5

) and 

Supplemental Label Flutriafol®250 g/L (EPA Reg No. 67760-

6

).

The estimated drinking water concentrations (EDWCs) for this drinking water exposure

assessment used the FIRST (surface water) and PRZM-GW (groundwater) models7and are

based upon the maximum number of applications, maximum single and yearly application rates,

and minimum reapplication intervals (Tables 2 and 3).

The EDWCs for flutriafol in groundwater and surface water for use in the human health risk 

assessment are provided in Table 1. For the proposed new uses, the EDWCs for flutriafol in 

surface source drinking water are not expected to exceed 28.2 μg/L for peak and the 2.8 μg/L for 

long-term average concentrations. The EDWCs for flutriafol in groundwater source drinking 

water are not expected to exceed 133 μg/L for peak and the 124 μg/L for long-term average 

concentrations. In previous assessments, similar EDWCs for flutriafol use on grapes were 

predicted using the PRZM-GW (D4128828). EFED recommends that the Health Effects Division 

use 133 μg/L for the peak concentration and the 124 μg/L for long-term average concentration in 

the human health assessment. 

Table 1. Maximum Tier I EDWCs in μg/L resulting from the use of flutriafol.

Drinking water source (model) 1-in-10 year 30-year simulation 

Acute Chronic Acute Chronic/Cancer

Current Assessment

Surface water (FIRST) 28.2 2.8

Ground water (PRZM-GW) - - 133 124

Groundwater (SCI-GROW) 10.3 10.3 - -

Previous Drinking Water Assessment (D412882)

Surface water (FIRST) 29.48 2.92 - 4.03

Ground water (PRZM-GW) - - 132 122

Groundwater (SCI-GROW) 10.2 10.2 - -

Previously, HED determined that the 1,2,4-triazole (and the triazole conjugates) degradates 

should be considered residues of concern in the human health risk assessment. 1,2,4-Triazole and 

triazole conjugates triazole analine and triazole acetic acid, are common degradates of conazole 

 

3

Flutriafol 500 g/L Proposed Label 67760-REA 9 5 2013

4 Topguard Fungicide Flutriafol New Uses Eco RA DP 412160

5

67760-REN Flutriafol 250 Draft Label

6

67760-REN Flutriafol 250 Draft Supplemental Label.

7

http://www.epa.gov/oppefed1/models/water/models4.htm and http://www.epa.gov/oppefed1/models/water/

8 Wolf, J. Drinking Water Assessment for Proposed New Uses (R190, PP# 3F8174) for Flutriafol for the establishment of tolerances for residue 

on cucurbit vegetables, fruiting vegetables, strawberries, tree nuts, and wheat and label amendment to change the pre-harvest interval (PHI) 

(R298, PP# 3F8156) for field corn and popcorn. D412882, October 29, 2013.
3

pesticides, and are addressed in a separate document9 which was prepared by EFED to address 

the inclusions of 1,2,4-Triazole and triazole conjugates in Tier 2 drinking water assessments. 

Due to the persistence of flutriafol, exposure to 1,2,4-triazole (and the triazole conjugates) 

degradates is expected to be very low. Additional details concerning these degradates can be 

found in prior drinking water assessments (D41288210).

Proposed New Uses

TOPGUARD®fungicide is formulated as a suspension concentrate containing 11.8 % of the 

active ingredient (a.i.) flutriafol (1.04 lb a.i./gallon of product). Flutriafol®250 g/L is formulated 

as a suspension concentrate containing 22.7% flutriafol (2.08 lb a.i. per gallon of product) and 

Flutriafol®500 g/L is formulated as suspension concentrate containing 42.0% flutriafol (4.16 lb 

a.i. per gallon of product).

The proposed methods of application are broadcast foliar by ground and air spray methods for all 

the proposed uses except for cotton, where it is proposed that one T-band (soil applied) will be

followed by a maximum of 2 foliar applications for cotton. Flutriafol may not be applied by

chemigation. The labels submitted for the 3F8199 tolerance petition specified the maximum 

allowable rate of use on a per year basis (i.e., lb a.i./A/year), while the labels submitted for the 

3F8174 tolerance petition specified a maximum use rate on a per season (i.e., lb a.i./A/season) 

basis. The number of seasons per year is not specified. For this assessment it is assumed that

there is only 1 season per year. 

Table 2. Summary of Proposed New Uses

Formulation 

(Method of 

Application)

Crop Maximum Single 

Application Rate 

 lb a.i./A (fl oz/A)

Number of Applications 

(Minimum 

Reapplication 

Interval)

Maximum Yearly Use Rate

 lb a.i./A per period (fl oz a.i./A per 

period)

Broadcast 

Foliar 

Spray

Leafy Vegetables 

(except Brassica 

Vegetables)

0.114 (7) 4 (7-day) 0.456 (28 per year)b

(AS&GS) Leafy Vegetables 

Brassica (cole and 

celery) 

0.114 (7) 4 (7- day) 0.456 (28 per year)b

Almonds, Pecans, tree 

nuts

0.114 (14) 4 (7-day) 0.456 (56 per year)a

0.456 (56 per season)d

Almond & Walnuts 0.114 ( 7) 4 (7-day) 0.456 (28 per year)b

0.456 (28 per season)e,f

Strawberry 0.114 ( 7) 4 (7-day) 0.456 (28 per season)b

0.456 (28 per season)

e,f

Fruiting Vegetables 0.114 (14) 4 (7-day) 0.456 (56 per year)a

0.456 (56 per season)d

Cucurbit Vegetables 0.114 (14) 4 (7-day) 0.456 (56 per year)a

0.456 (56 per season)d

Peanuts 0.114 (14) 4 (14-day) 0.456 (56 per year)a

0.456 (56 per season)d

 

9

1,2,4-Triazole, Triazole Alanine, Triazole Acetic Acid: Drinking Water Assessment in Support of Reregistration and Registration Actions for 

Triazole-derived Fungicide Compounds. 02/28/06. PC 600074, 600011, 600082 D320682.

10 Wolf, J.K. 2013. Drinking Water Assessment for Proposed New Uses (R190, PP# 3F8174) for Flutriafol for the establishment of tolerances for 

residue on cucurbit vegetables, fruiting vegetables, strawberries, tree nuts, and wheat and label amendment to change the pre-harvest interval 

(PHI) (R298, PP# 3F8156) for field corn and popcorn. D412882; October 29, 2013.
4

Formulation 

(Method of 

Application)

Crop Maximum Single 

Application Rate 

 lb a.i./A (fl oz/A)

Number of Applications 

(Minimum 

Reapplication 

Interval)

Maximum Yearly Use Rate

 lb a.i./A per period (fl oz a.i./A per 

period)

Tomatoes 0.114 ( 7) 4 ( 7-day) 0.456 (28 per season)

b

0.456 (28 per season)

e,f

Wheat (spring-winter) 0.114 (14) 2 (7-day) 0.228 (28 per year)a

0.228 (28 per season)d

Grain Sorghum 0.114 (14) 2 (7- day) 0.228 (28 per season)a

Soil Applied

Broadcast 

Foliar 

Spray

Cotton (T-Band) 0.260 ( 8) 1 at plant 0.260 ( 8/season)c

Cotton (Foliar) 0.114 (14) 2 Foliar (7-day) 0.228 (28/year)a,b

Total Cotton [T-Band + 

Cotton Foliar]

0.26 ( 8) 

0.228 (2 x 7)

Combined 0.488 lb a.i./A/yeara,b,c

 

Submitted Proposed Draft Labels.

File ID (name) of Submitted Proposed Label Proposed Label

[Product, EPA Reg. #; % a.i., lb a.i./fl oz]

Maximum Rate Expressed in

lb a.i./A/period

DP Barcode D412294; D415850 Tolerance Petition 3F8199

a Topguard Fungicide 67760-75 Proposed Label 

9 5 2013 for Tol Petition No. 3F8199

Topguard®Fungicide 67760-75 

[11.8% a.i.; 0.008125 lb a.i./fl oz] 

lb a.i./A/year

b Flutriafol 250 g/L SC 67760 129 Proposed 

Label 9 5 2013 for Tol Petition No. 3F8199

Flutriafol®250 g/L SC Fungicide 67760-120 

[22.7% a.i.; 0.01625 lb a.i./fl oz]

lb a.i./A/year

c Flutriafol 500 g/L Proposed Label 67760-REA 

9 5 2013

Flutriafol®500 g/L SC Fungicide 67760-REA

[42.0% a.i.; 0.0325 lb a.i./fl oz]

(lb a.i./A/season 

DP Barcode: D412160; Tolerance Petition 3F8174

d

Flutriafol New Uses Eco RA DP 412160 667760-75 Topguard®Fungicide 67760-75 

[11.8% a.i.; 0.008125 lb a.i./fl oz] 

lb a.i./A/season

e 67760-REN Flutriafol 250 draft label Flutriafol®

250 g/L Fungicide 67760-REN

[22.8% a.i.; 0.01625 lb a.i./fl]

lb a.i./A/season

f

67760-REN Flutriafol 250 Draft Supplemental 

Label

Flutriafol®250 g/L Fungicide 67760-REN Draft Supplemental 

Label [22.8% a.i.; 0.01625 lb a.i./fl]

lb a.i./A/season

Although, three different product formulations are proposed which contain different amounts (lb 

per gallon) of active ingredient (11.8, 22.8, and 42.0% a.i.), the maximum single application 

rates are the same for all three formulations when applied foliarly (0.114 lb a.i./A) are the same. 

A higher single application rate is proposed for the soil applied (T-Band) use for cotton (0.26 lb 

a.i./A). For the foliar uses, up to four 0.114 lb a.i./A applications per year (0.456 lb a.i./A/year)

may be applied (except grain sorghum where only 2 are proposed). For cotton, it is proposed that 

one 0.26 lb a.i./A T-Band application follow by a maximum of 2 foliar applications (0.114 lb 

a.i./A) for a yearly maximum of 0.488 lb a.i./A/year.

Table 3. Maximum Flutriafol Application Rates for Proposed New Uses.

Crop or Crop Group

Maximum Single 

Application Rate (lb 

a.i./A)

Number of Applications 

(Minimum Reapplication 

Interval)

Maximum Yearly Use Rate 

(lb a.i./A/year)

All uses except Grain Sorghum and Cotton 0.114 4 (7-day) 0.456

Grain sorghum 0.114 2 (7-day) 0.228

Cotton T-Band Appl. 0.260 (T-band, at plant) 0.260

Foliar 0.114 2 (Foliar, 7-day) 0.228

Combined for

Cotton

0.228

0.260

2 (Foliar, 7-day)

1 (T-Band Appl)

0.448 
5

Environmental Fate and Transport Characterization

Flutriafol is expected to be persistent in soil and moderately mobile in the environment, with its 

major routes of dissipation by runoff and leaching through the soil and through biotic 

degradation in aquatic environments (Table 4). Flutriafol is expected to dissipate slowly with a 

half-life of years [never achieved in studies] in the terrestrial environment and therefore repeated 

applications may lead to accumulation of flutriafol residues in soil. Flutriafol is expected to reach 

surface water through drift, runoff, and leaching. Additionally, it is expected to leach into 

groundwater. Detailed information on the environmental fate of flutriafol can be found in prior 

assessments (D360863, D356830, D340508, D396757).

Table 4. Summary of physical/chemical and environmental fate and transport properties of flutriafol. 

Parameter Value(s) (units) Source (MRID) Comment

Chemical Name Flutriafol

CAS Name:

α-(2-fluorophenyl)-α-(4-fluorophenyl)-

1H-1,2,4-triazole-1-ethanol

IUPAC Name: 

(RS-1-(2-fluorophenyl)-α-(4-

fluorophenyl)-1H-1,2,4-triazole-1-

ethanol

47129901

-

Chemical Structure -

Molecular Formula C16H13F2N3O 47129901 -

Molecular Weight 301.3 amu 47129901 -

Solubility (20 °C) 130 mg/L or ppm 47129901 -

Vapor Pressure (20 °C) 4 x 10-7Pa 

3.00025x10-9torr

47129901 -

Henry’s Law constant 9.16 x10-12 atm m3/mol - Calculated

pKa (20 °C) 2.3 47129901 -

Octanol-Water Partition 

Coefficient 

(log KOW @ pH 7)

2.29 47129901 -

Hydrolysis Half-life 

(t1⁄2) pH 5 and 7

Stable 47090416 Stable at all pHs.

Aqueous Photolysis 

Half-life (t1⁄2)

Stable 47090417 -
6

Parameter Value(s) (units) Source (MRID) Comment

Soil Photolysis Halflife (t1⁄2)

Stable 47090420

47418401

D353179 

D350986

Aerobic Soil 

Metabolism Half-life 

(t1⁄2)

697 weeks

120, 161, 257, 84, 98, and 315 weeks

347, 239, and 3,466 weeks

47090421

47090422

47090423

Note: values in 

weeks

Anaerobic Aquatic 

Metabolism (t1⁄2)

t1/2 = 6,932, 840, 1127, 1799, 588, 686, 

2205 days 

47090424 (Total system)

Aerobic Aquatic 

Metabolism 

t1/2 = 42.6 and 36.3 days 47090419 (Total system)

Organic Carbon 

Partition

Coefficient (KOC)

498, 205, 379, 230, 340, 428, 140 

mL/gOC

47090425

47090426

47090427

-

Soil Partition 

Coefficient (Kd)

3.7, 13.6, 10.6, 6.5, 2.0 mL/g 47090425

47090426

47090427

-

Terrestrial Field 

Dissipation

Half-life (t1⁄2)

t1/2 = 1155 days 

3466 days

2310 days

1155, 866, 770, 866, 1155, 1386 

days

47115502

47090431

- Loamy sand.

- Clay loam.

- Sandy clay loam. 

- Study conducted 

at 6 sites in 

Germany, soil 

texture classes

were not 

reported. 

No major degradation products (i.e., > 10% of applied radioactivity) were identified in any water 

or soil studies. No major flutriafol degradates have been identified in any submitted studies. The 

degradates formed in laboratory studies are discussed in detail in prior assessments (D412882). 

Two minor degradation products11 were identified in the photolysis on soil study [1H-1,2,4-

Triazole and 2,4’-Difluorobenzophenone] and three minor [1H-1,2,4-Triazole; Triazole-1-acetic 

acid; 1,2,4-Triazole-1-alanine] degradation products were identified in the anaerobic aquatic 

metabolism study (Figure 1).

 

11 Note the previous drinking water assessment (D360863) incorrectly included the 1,2,4-Triazole-1- acetic acid degradate. This error would not 

change the estimated drinking water concentrations (EDWCs).
7

1,2,4-Triazole

(1,2,4-T; free triazole)

Triazole Alanine

(TA)

Triazole Acetic Acid

(TAA)

Figure 1. Chemical structures for 1,2,4-triazole, triazole alanine, and triazole acetic acid

With the exception of 1,2,4-triazole (and the triazole conjugates), none of the other flutriafol 

degradates noted above were considered of concern by HED. 1,2,4-Triazole and triazole 

conjugates triazole analine and triazole acetic acid, common degradates of conazole pesticides, 

were addressed in a separate document12 which was prepared by EFED to address the inclusions 

of 1,2,4-Triazole and triazole conjugates in Tier 2 drinking water assessments. The Tier 2 

Triazole drinking water assessment was designed to be conservative. Because of the persistence 

of flutriafol, the percentages of 1,2,4-triazole residues formed by the degradation of flutriafol are 

expected to be much lower than other conazoles pesticides considered in drinking water 

assessments. Therefore, the assessment for the conazole class of pesticides should still be 

conservative. 

Six terrestrial field dissipation studies with applications made over several consecutive years, 

most with applications over multiple years, also indicate that flutriafol residues will remain 

essentially un-degraded, allowing residues to carry-over from year to year under actual use 

conditions. Due to the length of the environmental fate studies, and the persistence of flutriafol, 

major degradates were not detected in either laboratory or field studies. 

Limited monitoring data supports the potential for flutriafol to leach to groundwater. Flutriafol 

was detected (0.0051 μg/L) in groundwater in a study conducted in Ireland13. Seven flutriafol 

detections (detection limit = 0.021 μg/L) were reported in three public wells in the United 

Kingdom, during a three year period (June 2000 to February 2003)14.

Modeling

The Tier 1 drinking water assessment uses the PRZM-GW and SCI-GROW models for 

groundwater and the FIRST model for surface water. Both SCI-GROW and FIRST are not 

scenario specific, so the estimated concentrations are based upon the environmental fate 

properties and the maximum application number and rates and minimum reapplication interval.

 

12 1,2,4-Triazole, Triazole Alanine, Triazole Acetic Acid: Drinking Water Assessment in Support of Reregistration and Registration Actions for 

Triazole-derived Fungicide Compounds. 02/28/06. PC 600074, 600011, 600082 D320682.

13 Regional Groundwater Monitoring Network, 2005. Northern Ireland. Environmental & Heritage Service. 

http://www.doeni.gov.uk/niea/groundwater_2005_report.pdf. 

14 Stuart et al. 2006. http://onlinelibrary.wiley.com/doi/10.1111/j.1745-6592.2006.00113.x/pdf

NH

N N N

N

N

N H 2

O O H

N

N

N

O

OH
8

The six standard PRZM-GW scenarios15 used in the groundwater simulations were developed to 

be representative of known vulnerable sites—shallow, unconfined aquifers under an agricultural 

field with leaching prone soil and adequate precipitation and/or irrigation. Output values 

represent pesticide concentrations that may be observed in private drinking water wells resulting 

from the use of groundwater vulnerable to pesticide contamination. The results are expected to 

represent the upper bound values on the concentrations of flutriafol that might be found in 

drinking water supplied by vulnerable groundwater sources. The selection and procedures for 

selecting model input parameters followed EFED guidance16.

Groundwater Concentrations

PRZM-GW (Version 1.01) is a graphical user interface (GUI) for running the Pesticide Root 

Zone Model (PRZM) to estimate exposure in a shallow, unconfined, aquifer following pesticide 

application to an agricultural field. PRZM was developed by the U.S. EPA to simulate the 

vertical movement of pesticides in the unsaturated soil, within and below the plant root zone, and 

extending to the water table using generally available input data (Carsel et al., 198417). PRZM is 

also currently used by EFED in combination with EXAMS18 to estimate pesticide concentrations 

in surface water. Groundwater EDWCs with PRZM-GW are simulated for 30 years as done with 

PRZM/EXAMS for surface water. Unlike SCI-GROW, estimated groundwater concentrations 

are influenced by both the soil and hydrology of the specific scenario. The SCI-GROW model

considers only a single year’s application.

The basic input requirements for PRZM-GW are summarized in Table 5. The mean (4,048 days) 

and 90 percent upper bound of the mean (7,202 days) aerobic soil metabolism half-lives were 

recalculated. It should be also noted that the EFED guidance on model input parameter selection 

and preparation has evolved over time. Following current model input guidance, the mean Koc

(322 mL/goc) was used with the PRZM-GW and FIRST models because the sorption coefficients 

(Kd) values were significantly correlated [r2= 0.84; F test regression; p-value=0.0024] to the soil 

organic carbon content (OC). In prior assessments [D360863] the lowest Koc (140 mL/goc) was

used with the FIRST model (which followed guidance applicable at time, and has since been 

updated) and SCI-GROW (consistent with current guidance). The percent crop area (PCA)

19 is 

0.91. Because this version of PRZM-GW does not allow for multiple application methods the 

results from the T-Band and foliar applications are run separately and the results are added 

together.

Table 5. PRZM-GW input parameter values for flutriafol.

Parameter (units) Value Source 

(MRID)

Comment

Organic Carbon Partition

Coefficient (Koc; mL/goc)

322

47090425

47090426

47090427

Represents the mean value of seven values 

ranging from 140 to 498 mL/g for the parent 

compound. 

 

15 Florida Citrus, Florida Potato, Wisconsin Corn, Georgia Peanuts, North Carolina Cotton, and Delmarva Sweet Corn.

16 http://www.epa.gov/oppefed1/models/water/input_parameter_guidance.htm

17 Carsel, R.F.; Smith, C.N.; Mulkey, L.A.; Dean, J.D; Jowise, P. Users Manual for the Pesticide Root Zone Model (PRZM) Release 1. 

December 1984. EPA-600/3-84-109. Environmental Research Laboratory, Office of Research and Development, U.S. Environmental 

Protection Agency, Athens, GA, 227 pp. 

18 Burns, L. A. 2002. EXAMS (Exposure Analysis Modeling System) Version 2.98.04.06. Environmental Research Laboratory. U. S. 

Environmental Protection Agency. Athens, GA.

19 http://www.epa.gov/oppefed1/models/water/pca_adjustment_dwa.html
9

Parameter (units) Value Source 

(MRID)

Comment

Aerobic Soil Metabolism Halflife (t1⁄2) (days) 

7,202 days 47090421

47090422

47090423

Recalculated value the represents 90% 

confidence interval for 10 values from the 

aerobic soil metabolism of the parent 

compound. (See Appendix 1)

Application Rates, Number, 

Interval See Table 2 - Specified on label

Application Date:

T-Band

Foliar Application

-7 days b.e.

101 days a.e.

Application can be specified by date or by days 

before or after crop emergence.

b.e. - before emergence (defined by scenario)

a.e. - after emergence (defined by scenario)

The SCI-GROW20 model (Version 2.3) is also used as a groundwater screening exposure value 

to be used in determining the potential risk to human health from drinking water contaminated 

with the pesticide. Fate input parameters used in SCI-GROW are presented in Table 7. 

Table 7. SCI-GROW (v2.3) input parameter values for flutriafol.

Parameter (units) Value Source 

(MRID)

Comment

Organic Carbon Partition 

Coefficient (Koc; mL/goc)

Lowest: 140

47090425

47090426

47090427

Represents the lowest non-sand (texture 

class) value of seven values ranging from 

140 to 498 mL/g for the parent compound. 

Aerobic Soil Metabolism Half-life 

(t1⁄2) (days) 

Mean=

4,047.6

47090421

47090422

47090423

Mean value of the 10 aerobic soil 

metabolism of the parent compound.

The peak groundwater EDWCs estimated by PRZM-GW ranged from 28 to 133 μg/L and the 

simulation averages ranged from 21 to 124 μg/L (Table 6). The Florida Central Ridge and North 

Carolina Eastern Coastal Plains had the highest EDWCs. The maximum EDWCs estimated for 

the proposed uses are essentially the same as the maximum EDWCs most recent EDWCs for 

flutriafol (parent) are 132 μg/L for acute exposure and 122 μg/L for chronic/cancer exposure 

(D41288221). The differences are due different fate properties (i.e., aerobic soil half-life) and 

different application dates. Representative PRZM-GW and SCI-GROW input files are given in 

Appendix 2.

 

20 http://www.epa.gov/oppefed1/models/water/#scigrow

21 Wolf, J. Drinking Water Assessment for Proposed New Uses (R190, PP# 3F8174) for Flutriafol for the establishment of tolerances for residue 

on cucurbit vegetables, fruiting vegetables, strawberries, tree nuts, and wheat and label amendment to change the pre-harvest interval (PHI) 

(R298, PP# 3F8156) for field corn and popcorn. D412882, October 29, 2013.
10

Table 6. PRZM-GW (Version 1.01) estimates of flutriafol for the proposed new uses.

Flutriafol SCI-GROW

(1 Year 

Simulation)

PRZM-GW (version 1.03)

(30 Year Simulation)

Scenario (μg/L) Peak (μg/L) Post 

Breakthrough

Average (μg/L)

Average

Breakthrough 

Time (days)

Grain Sorghum 2 applications @ 0.114 lb a.i./A; 7-day reapplication interval

Delmarva 

4.8

50.3 43.2 2872

Florida Central Ridge 51.4 44.6 2865

Florida - potato 30.1 26.5 7035

GA - Southern Coastal Plain 24.6 21.6 6245

NC Eastern Coastal Plain - 61.6 51.7 3664

WI Central Sands 61.9 57.7 4018

4 applications @ 0.114 lb a.i./A; 7-day reapplication interval

Delmarva 

9.6

100 86.4 2872

Florida Central Ridge -citrus 103 89.2 2865

Florida – potato 30 yr 60.3 53.2 7031

GA - Southern Coastal Plain 49.2 43.2 6245

NC Eastern Coastal Plain - 123 104 3664

WI Central Sands 124 115 4018

Cotton 1 applications @ 0.26 a.i./A T-Band Application

Delmarva 

5.5

57.4 49.6 2872

Florida Central Ridge 58.9 50.4 2865

Florida – potato 34.5 30.5 7035

GA - Southern Coastal Plain 28 25 6245

NC Eastern Coastal Plain - 70.6 58.7 3664

WI Central Sands 71.6 66.7 4018

Cotton 2 applications @ 0.114 a.i./A; 7-day reapplication interval (with the T-Band Application)

Delmarva 

4.8

50.3 43.2 2872

Florida Central Ridge 51.4 44.6 2865

Florida – potato 30.1 26.5 7035

GA - Southern Coastal Plain 24.6 21.6 6245

NC Eastern Coastal Plain - 61.6 51.7 3664

WI Central Sands 61.9 57.7 4018

Cotton 1 application @ 0.26 lb a.i./A and 2 @ 0.114 lb a.i./A (7-day interval)

Delmarva 

10.2

107.7 92.8 2872

Florida Central Ridge 110.3 95.0 2864

Florida – potato 64.6 57.0 7035

GA - Southern Coastal Plain 52.6 46.6 6245

NC Eastern Coastal Plain - 132.2 110.4 3664

WI Central Sands 133.5 124.4 4018 
11

Surface Water Concentrations

OPP uses the Tier 1 model, FQPA Index Reservoir Screening Tool (FIRST, Version 1.1.1)

22, to 

estimate both acute and chronic potential pesticide concentrations in untreated surface source

drinking water. Input parameters for FIRST are listed in Table 8. For the foliar spray the aerial 

spray option in FIRST was used for the foliar applications and the ground spray T-Band option 

was used for cotton T-Band assessment. For the proposed new cotton use where 1 T-Band 

application (@ 0.26 lb a.i./A) is follow by 2 foliar applications (@ 0.114 lb a.i./A), the methods 

are simulated separately and added together.

Table 8. FIRST (v1.1.1) environmental fate and other select input parameter values for current flutriafol

assessment.

Parameter (units) Value Source (MRID) Comment

Percent Cropped Area (decimal) 0.91 National default

Soil Partition Coefficient ( KOC 

mL/gOC)

322 47090425

47090426

47090427

Represents the mean of seven values ranging 

from 140 to 498 mL/g for the parent compound. 

Aerobic Soil Metabolism Halflife (t1⁄2) (days)7,202 47090421

47090422

47090423

Recalculated value the represents 90% confidence 

interval for 10 values from the aerobic soil 

metabolism of the parent compound. (See 

Appendix 1).

Wetted in (yes or no) No Proposed label Not specified

Pesticide Application Method

[Default Options in FIRST]

A

B

Label

T-band option

Air Spray Drift=16.0%; Efficiency =0.95% 

Ground Spray Drift=6.4%; Efficiency 0.99%; 

Depth of Incorporation (inches) -

1.5 

For air spray depth is not specified

For T-Band an incorporation depth is required

Solubility in Water @ 20 OC, 

(mg/L or ppm)

130 47129901 -

Aerobic Aquatic Metabolism 

Half-life (t1⁄2) (days)

49.2 47090419 Represents the 90th percentile of the upper 

confidence bound on the mean of nine half-life 

values (39.5).

Hydrolysis Half-life @ pH 7 0 47090416 Stable

Aquatic Photolysis Half-life (t1⁄2) 

@ pH 7 

0 47287601

47090417

Stable

The flutriafol application rate information and surface water EDWCs are given in Table 9. 

Output from FIRST is presented in Appendix 3. The highest EDWCs are for the four foliar 

applications associated with the proposed use on leafy vegetables and grain sorghum. The 

maximum EDWCs are 28.2 and 2.8 μg/L for the acute and chronic exposure concentrations, 

respectively. Representative FIRST outputs are given in Appendix 3.

Table 9. Tier 1 FIRST Estimated Drinking Water Concentrations (EDWCs) for flutriafol for the proposed 

new uses.

 

22 http://www.epa.gov/oppefed1/models/water/#first
12

Use Single 

Application 

Rate

(lb a.i./A)

Number of 

Applications (interval)

Method of Application

Seasonal 

Application Rate

(lb a.i./A/year)

Acute 

EDWC

(μg/L)

Chronic 

EDWC

(μg/L)

Leafy Vegetables 0.114 4 (7-days) Foliar 0.456 28.2 2.8

Grain Sorghum 0.114 2 (7-days) Foliar 0.228 14.2 1.4

Grain Sorghum 0.114 4 (7-days) Foliar 0.456 28.2 2.8

Cotton 0.114 2 (7-days) Foliar 0.228 14.2 1.4

Cotton 0.260 1 (-) T-Band 0.260 10.9 1.1

Cotton -

a

1 T-Band + 2 Foliar 0.488 25.1 2.6

a

0.26 lb a.i./A + 2 @ 0.114 lb a.i./A
13

Appendix 1. Discussion on Aerobic Soil Metabolism Half-lives.

In several previous drinking water exposure assessments, the aerobic soil metabolism half-life 

value (588 days) was used as an input for groundwater modeling was incorrect (e.g., a unit 

error). The 90% upper bound on the mean was reported incorrectly as 588 days when it should 

have been reported as 588 weeks. This value, however, also appears to be the shortest half-life 

and not a mean or upper bound of the mean. The value was recalculated for days with a mean 

(3,957 days) and 90th percent upper bound of the mean (7,515 days) aerobic soil metabolism 

half-lives were recalculated in a response to the registrant concerning the PRZM-GW model 

(D396757). This error has no influence on the surface water EDWCs estimated using the FIRST 

model. Because the FIRST model is insensitive to half-lives greater than 365 days, it was

assumed for modeling purposes that there was no aerobic soil degradation, based upon the 

flutriafol aerobic soil metabolism studies where all the half-lives were greater than 365 days.

PRZM-GW has been found to be more much more sensitive to the aerobic soil metabolism halflife value selected for modeling potential groundwater contamination compared to surface water 

estimates with FIRST or PRZM/EXAMS 

Since the last drinking water assessments (D412882 10/29/13 and D396757 07/26/12), the

registrant has submitted a report (MRID 49177401) questioning several of the aerobic soil 

metabolism half-lives used to obtain the 90% upper bound on the mean half-life for modeling 

purposes23. While no new data has been submitted, EFED has considered the information 

submitted in the report (MRID 49177401). 

The half-lives estimated by the EPA (DERS) and the registrant (Table 5, MRID 49177401),

using linear and nonlinear regression techniques, were compared in Table 5 of MRID 49177401. 

While the values [linear compared to nonlinear] are not exactly the same (numerically), they are 

similar (generally varying only by 1 or 2 weeks) with the exception of the North Dakota soil 

(MRID 47090421) and the Speyer 2.2 sand soil (MRID 47090423). The North Dakota and the 

Speyer 2.2 soils are discussed in more detail in a following paragraph. The (paired) linear and 

nonlinear methods yielded similar half-lives (ranging from 83 weeks to 3,446 weeks). 

As noted in the registrants report (MRID 49177401), several of the soils tested did not result in 

statistically meaningful r2and p-values for linear regression or nonlinear regression. This 

suggests that either no aerobic metabolism of flutriafol occurred during the course of the study or 

that no clear degradation pattern was observed (i.e., lower value followed by higher values

resulting in regression with positive slopes). Therefore, the data illustrate the high persistence of 

flutriafol in aerobic soils. It should be noted here that these studies were conducted for a periods 

ranging from 126 to 365 days (MRIDs # 47090421, 47090422, 47090423) and since many of the 

studies showed very little degradation the DT50s, or half-lives, had to extrapolate far beyond the 

length of the study. 

 

23 http://www.epa.gov/oppefed1/models/water/input_parameter_guidance.htm
14

One of two of the half-life values specifically noted was for the North Dakota sandy loam 

(MRID 47090421), where the registrant indicates that the half-life of 4,878 days (regression 

slope =-1.4419e-4) would be a better estimate rather than the 6,932 days (regression slope = 

-1.00e-4) reported by the EPA in the DER. Note: both slope values are available with Sigma Plot 

output and page 50 of the study MRID 47090701 has the identical regression equation slope (-

0.0001) and intercept calculated by the EPA and included in the DER. The difference (4,878 and 

6,932 days) is solely based upon the significant figures of slope derived from the regression 

analysis. Both half-life values suggest minimal aerobic metabolism of flutriafol in soil, although 

the half-life estimated from the slope has more significant figures may be a better estimate. The 

Speyer 2.2 sand (MRID 47090423) had a report half-life of 24,252 days (3,466 weeks) which 

indicates little if any aerobic soil metabolism took place during the study. No information has 

been provided as to why this soil should not be included. The EPA also noted that a third soil 

(Warfield soil) from MRID 47090423 study had not been included previously when determining 

the upper bound of the mean for modeling purposes and has been added.

The half-lives from these studies are summarized in Appendix1Table 1 and the 90th percent 

upper bound on the mean for modeling purposes is recalculated the inclusion of the Warfield soil 

and updated half-life for the North Dakota soil with and without the Speyer 2.2 soil. The upper 

bound on the mean of all soils (n=10) is 7,202 days, which is slightly less than previous value of 

7,470 days (n=9), because of the addition of the Warfield soil. 

Appendix 1 Table 1. Summary of Aerobic Soil Metabolism Study Half-Lives and Upper of Mean for 

Modeling.

MRID # Soil Identification Half-life 

(weeks)a

Half-life 

(weeks)b

Half-life 

(weeks)c

Half-life (days)

(weekscx 7)

47090421 ND soil - - 697 4,878

47090422 18 acres (both labels) 121 120 120 837

47090422 Flexford 257 257 257 1,797

47090422 Boxford 98 98 98 683

47090422 Horsely 84 84 84 585

47090422 Frensham (both 

labels) 161 161 161 1,127

47090422 Chalgrove 315 315 315 2,205

47090423 Speyer 2.3 347 347 347 2,429

47090423 Warfield 239 239 239 1,673

47090423 Speyer 2.2 3,466 3,466 3,466 24,262

90% upper bound on mean all values = 7,201.9 days (mean = 4,047.6; std = 7,212.48, n = 10)c

a Values used to calculate 7,515 day upper bound half-life (Table 2; D396757); note 121 week value for the 18 acre soil compared to 120 week 

value.

b Values used to calculate the 7,470 day upper bound half-life (Tables 4 and 5; D412882); ND soil 697 weeks not included.

c Values used to calculate the 7,202 day upper bound half-life
15

Appendix 2. GROUNDWATER

PRZM-GW Input and Output

1 T-BAND APPLICATION @ 0.26 lb a.i./A

3/18/2014 12:08:46 PM; Flutriafol; Wisconsin Corn - WI Central Sands

User Interface Version: PRZM-GW (Version 1.01)

***Record 3 

 0.76 0.36 0 18 1 1

***Record 6

 0

***Record 8

 1

***Record 9

 1 0.25 90 100 1 10 10 10 0 100

***Record 10

 30

***Record 11

 010561 210761 201061 1

 010562 210762 201062 1

 010563 210763 201063 1

 010564 210764 201064 1

 010565 210765 201065 1

 010566 210766 201066 1

 010567 210767 201067 1

 010568 210768 201068 1

 010569 210769 201069 1

 010570 210770 201070 1

 010571 210771 201071 1

 010572 210772 201072 1

 010573 210773 201073 1

 010574 210774 201074 1

 010575 210775 201075 1

 010576 210776 201076 1

 010577 210777 201077 1

 010578 210778 201078 1

 010579 210779 201079 1

 010580 210780 201080 1

 010581 210781 201081 1

 010582 210782 201082 1

 010583 210783 201083 1

 010584 210784 201084 1

 010585 210785 201085 1

 010586 210786 201086 1

 010587 210787 201087 1

 010588 210788 201088 1

 010589 210789 201089 1

 010590 210790 201090 1

***Record 12

Place Holder

***Record 13

 30 1 0 0

***Record 15

Place Holder

***Record 16

 24 461 0 1 4 0.291 1 0

 24 462 0 1 4 0.291 1 0

 24 463 0 1 4 0.291 1 0

 24 464 0 1 4 0.291 1 0

 24 465 0 1 4 0.291 1 0

 24 466 0 1 4 0.291 1 0

 24 467 0 1 4 0.291 1 0

 24 468 0 1 4 0.291 1 0

 24 469 0 1 4 0.291 1 0

 24 470 0 1 4 0.291 1 0

 24 471 0 1 4 0.291 1 0

 24 472 0 1 4 0.291 1 0
16

 24 473 0 1 4 0.291 1 0

 24 474 0 1 4 0.291 1 0

 24 475 0 1 4 0.291 1 0

 24 476 0 1 4 0.291 1 0

 24 477 0 1 4 0.291 1 0

 24 478 0 1 4 0.291 1 0

 24 479 0 1 4 0.291 1 0

 24 480 0 1 4 0.291 1 0

 24 481 0 1 4 0.291 1 0

 24 482 0 1 4 0.291 1 0

 24 483 0 1 4 0.291 1 0

 24 484 0 1 4 0.291 1 0

 24 485 0 1 4 0.291 1 0

 24 486 0 1 4 0.291 1 0

 24 487 0 1 4 0.291 1 0

 24 488 0 1 4 0.291 1 0

 24 489 0 1 4 0.291 1 0

 24 490 0 1 4 0.291 1 0

***Record 17

 0 1 0

***Record 19

Place Holder

***Record 20

 1000 0 0 0 0 0 2 1 1 0

***Record 26

 0 0 0

***Record 27

 3 0.1 0.7 4.0

***Record 31

 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.97 10.0

***Record 32

 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6

***Record 32A

 2.00 25.0

***Record 33

 8

*** Record 34,36,37 Horizon 1

 1 10 1.63 0.088 0 0 0

 9.62E-059.62E-05 0

 1 0.088 0.034 0.46 1.4812

 5.6 95 2.3 0 0

*** Record 34,36,37 Horizon 2

 2 10 1.63 0.088 0 0 0

 9.09E-059.09E-05 0

 5 0.088 0.034 0.46 1.4812

 5.6 95 2.3 0 0

*** Record 34,36,37 Horizon 3

 3 20 1.68 0.079 0 0 0

 7.49E-057.49E-05 0

 20 0.079 0.025 0.14 0.4508

 5.6 96 2.5 0 0

*** Record 34,36,37 Horizon 4

 4 20 1.68 0.079 0 0 0

 5.35E-055.35E-05 0

 20 0.079 0.025 0.09 0.2898

 5.6 96 2.5 0 0

*** Record 34,36,37 Horizon 5

 5 20 1.59 0.068 0 0 0

 3.21E-053.21E-05 0

 20 0.068 0.016 0.09 0.2898

 5.6 97 1.7 0 0

*** Record 34,36,37 Horizon 6

 6 20 1.59 0.068 0 0 0

 1.07E-051.07E-05 0

 20 0.068 0.016 0.08 0.2576

 5.6 97 1.7 0 0

*** Record 34,36,37 Horizon 7

 7 800 1.59 0.068 0 0 0

 0 0 0

 50 0.068 0.016 0.07 0.2254
17

 5.6 97 1.7 0 0

*** Record 34,36,37 Horizon 8

 8 100 1.59 0.396 0 0 0

 0 0 0

 50 0.396 0.001 0.07 0.2254

 5.6 97 1.7 0 0

*** Record 40

 0

*** Record 42

 YEAR 10 YEAR 10 YEAR 10 0

*** Record 45

 3 YEAR

*** Record 46

 DCON1 TAVE 33 34 1.0E3

 INFL TCUM 33 33 0.00233

 IRRG TSER

4 Foliar Applications @ 0.114 lb a.i./A

3/18/2014 12:10:17 PM; Flutriafol; Wisconsin Corn - WI Central Sands

User Interface Version: PRZM-GW (Version 1.01)

***Record 3 

 0.76 0.36 0 18 1 1

***Record 6

 0

***Record 8

 1

***Record 9

 1 0.25 90 100 1 10 10 10 0 100

***Record 10

 30

***Record 11

 010561 210761 201061 1

 010562 210762 201062 1

 010563 210763 201063 1

 010564 210764 201064 1

 010565 210765 201065 1

 010566 210766 201066 1

 010567 210767 201067 1

 010568 210768 201068 1

 010569 210769 201069 1

 010570 210770 201070 1

 010571 210771 201071 1

 010572 210772 201072 1

 010573 210773 201073 1
18

 010574 210774 201074 1

 010575 210775 201075 1

 010576 210776 201076 1

 010577 210777 201077 1

 010578 210778 201078 1

 010579 210779 201079 1

 010580 210780 201080 1

 010581 210781 201081 1

 010582 210782 201082 1

 010583 210783 201083 1

 010584 210784 201084 1

 010585 210785 201085 1

 010586 210786 201086 1

 010587 210787 201087 1

 010588 210788 201088 1

 010589 210789 201089 1

 010590 210790 201090 1

***Record 12

Place Holder

***Record 13

 120 1 0 0

***Record 15

Place Holder

***Record 16

 10 861 0 1 4 0.128 1 0

 17 861 0 1 4 0.128 1 0

 24 861 0 1 4 0.128 1 0

 30 861 0 1 4 0.128 1 0

 10 862 0 1 4 0.128 1 0

 17 862 0 1 4 0.128 1 0

 24 862 0 1 4 0.128 1 0

 30 862 0 1 4 0.128 1 0

 10 863 0 1 4 0.128 1 0

 17 863 0 1 4 0.128 1 0

 24 863 0 1 4 0.128 1 0

 30 863 0 1 4 0.128 1 0

 10 864 0 1 4 0.128 1 0

 17 864 0 1 4 0.128 1 0

 24 864 0 1 4 0.128 1 0

 30 864 0 1 4 0.128 1 0

 10 865 0 1 4 0.128 1 0

 17 865 0 1 4 0.128 1 0

 24 865 0 1 4 0.128 1 0

 30 865 0 1 4 0.128 1 0

 10 866 0 1 4 0.128 1 0

 17 866 0 1 4 0.128 1 0

 24 866 0 1 4 0.128 1 0

 30 866 0 1 4 0.128 1 0

 10 867 0 1 4 0.128 1 0

 17 867 0 1 4 0.128 1 0

 24 867 0 1 4 0.128 1 0

 30 867 0 1 4 0.128 1 0

 10 868 0 1 4 0.128 1 0

 17 868 0 1 4 0.128 1 0

 24 868 0 1 4 0.128 1 0

 30 868 0 1 4 0.128 1 0

 10 869 0 1 4 0.128 1 0

 17 869 0 1 4 0.128 1 0

 24 869 0 1 4 0.128 1 0

 30 869 0 1 4 0.128 1 0

 10 870 0 1 4 0.128 1 0

 17 870 0 1 4 0.128 1 0

 24 870 0 1 4 0.128 1 0

 30 870 0 1 4 0.128 1 0

 10 871 0 1 4 0.128 1 0

 17 871 0 1 4 0.128 1 0

 24 871 0 1 4 0.128 1 0

 30 871 0 1 4 0.128 1 0

 10 872 0 1 4 0.128 1 0

 17 872 0 1 4 0.128 1 0

 24 872 0 1 4 0.128 1 0
19

 30 872 0 1 4 0.128 1 0

 10 873 0 1 4 0.128 1 0

 17 873 0 1 4 0.128 1 0

 24 873 0 1 4 0.128 1 0

 30 873 0 1 4 0.128 1 0

 10 874 0 1 4 0.128 1 0

 17 874 0 1 4 0.128 1 0

 24 874 0 1 4 0.128 1 0

 30 874 0 1 4 0.128 1 0

 10 875 0 1 4 0.128 1 0

 17 875 0 1 4 0.128 1 0

 24 875 0 1 4 0.128 1 0

 30 875 0 1 4 0.128 1 0

 10 876 0 1 4 0.128 1 0

 17 876 0 1 4 0.128 1 0

 24 876 0 1 4 0.128 1 0

 30 876 0 1 4 0.128 1 0

 10 877 0 1 4 0.128 1 0

 17 877 0 1 4 0.128 1 0

 24 877 0 1 4 0.128 1 0

 30 877 0 1 4 0.128 1 0

 10 878 0 1 4 0.128 1 0

 17 878 0 1 4 0.128 1 0

 24 878 0 1 4 0.128 1 0

 30 878 0 1 4 0.128 1 0

 10 879 0 1 4 0.128 1 0

 17 879 0 1 4 0.128 1 0

 24 879 0 1 4 0.128 1 0

 30 879 0 1 4 0.128 1 0

 10 880 0 1 4 0.128 1 0

 17 880 0 1 4 0.128 1 0

 24 880 0 1 4 0.128 1 0

 30 880 0 1 4 0.128 1 0

 10 881 0 1 4 0.128 1 0

 17 881 0 1 4 0.128 1 0

 24 881 0 1 4 0.128 1 0

 30 881 0 1 4 0.128 1 0

 10 882 0 1 4 0.128 1 0

 17 882 0 1 4 0.128 1 0

 24 882 0 1 4 0.128 1 0

 30 882 0 1 4 0.128 1 0

 10 883 0 1 4 0.128 1 0

 17 883 0 1 4 0.128 1 0

 24 883 0 1 4 0.128 1 0

 30 883 0 1 4 0.128 1 0

 10 884 0 1 4 0.128 1 0

 17 884 0 1 4 0.128 1 0

 24 884 0 1 4 0.128 1 0

 30 884 0 1 4 0.128 1 0

 10 885 0 1 4 0.128 1 0

 17 885 0 1 4 0.128 1 0

 24 885 0 1 4 0.128 1 0

 30 885 0 1 4 0.128 1 0

 10 886 0 1 4 0.128 1 0

 17 886 0 1 4 0.128 1 0

 24 886 0 1 4 0.128 1 0

 30 886 0 1 4 0.128 1 0

 10 887 0 1 4 0.128 1 0

 17 887 0 1 4 0.128 1 0

 24 887 0 1 4 0.128 1 0

 30 887 0 1 4 0.128 1 0

 10 888 0 1 4 0.128 1 0

 17 888 0 1 4 0.128 1 0

 24 888 0 1 4 0.128 1 0

 30 888 0 1 4 0.128 1 0

 10 889 0 1 4 0.128 1 0

 17 889 0 1 4 0.128 1 0

 24 889 0 1 4 0.128 1 0

 30 889 0 1 4 0.128 1 0

 10 890 0 1 4 0.128 1 0

 17 890 0 1 4 0.128 1 0
20

 24 890 0 1 4 0.128 1 0

 30 890 0 1 4 0.128 1 0

***Record 17

 0 1 0

***Record 19

Place Holder

***Record 20

 1000 0 0 0 0 0 2 1 1 0

***Record 26

 0 0 0

***Record 27

 3 0.1 0.7 4.0

***Record 31

 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.97 10.0

***Record 32

 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6

***Record 32A

 2.00 25.0

***Record 33

 8

*** Record 34,36,37 Horizon 1

 1 10 1.63 0.088 0 0 0

 9.62E-059.62E-05 0

 1 0.088 0.034 0.46 1.4812

 5.6 95 2.3 0 0

*** Record 34,36,37 Horizon 2

 2 10 1.63 0.088 0 0 0

 9.09E-059.09E-05 0

 5 0.088 0.034 0.46 1.4812

 5.6 95 2.3 0 0

*** Record 34,36,37 Horizon 3

 3 20 1.68 0.079 0 0 0

 7.49E-057.49E-05 0

 20 0.079 0.025 0.14 0.4508

 5.6 96 2.5 0 0

*** Record 34,36,37 Horizon 4

 4 20 1.68 0.079 0 0 0

 5.35E-055.35E-05 0

 20 0.079 0.025 0.09 0.2898

 5.6 96 2.5 0 0

*** Record 34,36,37 Horizon 5

 5 20 1.59 0.068 0 0 0

 3.21E-053.21E-05 0

 20 0.068 0.016 0.09 0.2898

 5.6 97 1.7 0 0

*** Record 34,36,37 Horizon 6

 6 20 1.59 0.068 0 0 0

 1.07E-051.07E-05 0

 20 0.068 0.016 0.08 0.2576

 5.6 97 1.7 0 0

*** Record 34,36,37 Horizon 7

 7 800 1.59 0.068 0 0 0

 0 0 0

 50 0.068 0.016 0.07 0.2254

 5.6 97 1.7 0 0

*** Record 34,36,37 Horizon 8

 8 100 1.59 0.396 0 0 0

 0 0 0

 50 0.396 0.001 0.07 0.2254

 5.6 97 1.7 0 0

*** Record 40

 0

*** Record 42

 YEAR 10 YEAR 10 YEAR 10 0

*** Record 45

 3 YEAR

*** Record 46

 DCON1 TAVE 33 34 1.0E3

 INFL TCUM 33 33 0.00233

 IRRG TSER
21

SCI-GROW OUTPUT

 SCIGROW

 VERSION 2.3

 ENVIRONMENTAL FATE AND EFFECTS DIVISION

 OFFICE OF PESTICIDE PROGRAMS

 U.S. ENVIRONMENTAL PROTECTION AGENCY

 SCREENING MODEL

 FOR AQUATIC PESTICIDE EXPOSURE

SciGrow version 2.3

chemical:flutriafol

time is 3/12/2014 8:31:22

------------------------------------------------------------------------

 Application Number of Total Use Koc Soil Aerobic

 rate (lb/acre) applications (lb/acre/yr) (ml/g) metabolism (days)

------------------------------------------------------------------------

 0.488 1.0 0.488 1.40E+02 4047.6

------------------------------------------------------------------------

groundwater screening cond (ppb) = 1.02E+01 

************************************************************************
22

Appendix 3 Surface Water FIRST OUTPUT

4 applications @ 0.114 lb ai/A; 7 day interval

RUN No. 1 FOR flutriafol ON 4 apps * INPUT VALUES * 

 --------------------------------------------------------------------

 RATE (#/AC) No.APPS & SOIL SOLUBIL APPL TYPE %CROPPED INCORP

 ONE(MULT) INTERVAL Koc (PPM ) (%DRIFT) AREA (IN)

 --------------------------------------------------------------------

 0.114( 0.456) 4 7 322.0 130.0 AERIAL(16.0) 91.0 0.0

 FIELD AND RESERVOIR HALFLIFE VALUES (DAYS) 

 --------------------------------------------------------------------

 METABOLIC DAYS UNTIL HYDROLYSIS PHOTOLYSIS METABOLIC COMBINED

 (FIELD) RAIN/RUNOFF (RESERVOIR) (RES.-EFF) (RESER.) (RESER.) 

 --------------------------------------------------------------------

 7202.00 2 0.00 0.00- 0.00 49.20 49.20

 UNTREATED WATER CONC (MICROGRAMS/LITER (PPB)) Ver 1.1.1 MAR 26, 2008

 --------------------------------------------------------------------

 PEAK DAY (ACUTE) ANNUAL AVERAGE (CHRONIC) 

 CONCENTRATION CONCENTRATION 

 --------------------------------------------------------------------

 28.169 2.803

 

2 applications @ 0.114 lb ai/A; 7 day interval 

RUN No. 2 FOR flutriafol ON grain sorg * INPUT VALUES * 

 --------------------------------------------------------------------

 RATE (#/AC) No.APPS & SOIL SOLUBIL APPL TYPE %CROPPED INCORP

 ONE(MULT) INTERVAL Koc (PPM ) (%DRIFT) AREA (IN)

 --------------------------------------------------------------------

 0.114( 0.228) 2 7 322.0 130.0 AERIAL(16.0) 91.0 0.0

 FIELD AND RESERVOIR HALFLIFE VALUES (DAYS) 

 --------------------------------------------------------------------

 METABOLIC DAYS UNTIL HYDROLYSIS PHOTOLYSIS METABOLIC COMBINED

 (FIELD) RAIN/RUNOFF (RESERVOIR) (RES.-EFF) (RESER.) (RESER.) 

 --------------------------------------------------------------------

 7202.00 2 N/A 0.00- 0.00 49.20 49.20

 UNTREATED WATER CONC (MICROGRAMS/LITER (PPB)) Ver 1.1.1 MAR 26, 2008

 --------------------------------------------------------------------

 PEAK DAY (ACUTE) ANNUAL AVERAGE (CHRONIC) 

 CONCENTRATION CONCENTRATION 

 --------------------------------------------------------------------

 14.198 1.415
23

1 application @ 0.26 lb ai/A T-Band application

 RUN No. 3 FOR flutrial ON cotton t-b * INPUT VALUES * 

 --------------------------------------------------------------------

 RATE (#/AC) No.APPS & SOIL SOLUBIL APPL TYPE %CROPPED INCORP

 ONE(MULT) INTERVAL Koc (PPM ) (%DRIFT) AREA (IN)

 --------------------------------------------------------------------

 0.260( 0.260) 1 1 322.0 130.0 GROUND( 6.4) 91.0 1.5

 FIELD AND RESERVOIR HALFLIFE VALUES (DAYS) 

 --------------------------------------------------------------------

 METABOLIC DAYS UNTIL HYDROLYSIS PHOTOLYSIS METABOLIC COMBINED

 (FIELD) RAIN/RUNOFF (RESERVOIR) (RES.-EFF) (RESER.) (RESER.) 

 --------------------------------------------------------------------

 7202.00 2 N/A 0.00- 0.00 49.20 49.20

 UNTREATED WATER CONC (MICROGRAMS/LITER (PPB)) Ver 1.1.1 MAR 26, 2008

 --------------------------------------------------------------------

 PEAK DAY (ACUTE) ANNUAL AVERAGE (CHRONIC) 

 CONCENTRATION CONCENTRATION 

 --------------------------------------------------------------------

 10.885 1.078