EX-10.27



 Exhibit 10.27 

IGNYTA, INC. 
 NON-EMPLOYEE DIRECTOR COMPENSATION PROGRAM 
 Effective as of March 9, 2017 

Non-employee members of the board of directors (the “Board”) of Ignyta, Inc.
(the “Company”) shall be eligible to receive cash and equity compensation as set forth in this Non-Employee Director Compensation Program (this “Program”). The
cash and equity compensation described in this Program shall be paid or be made, as applicable, automatically and without further action of the Board, to each member of the Board who is not an employee of the Company or any parent or subsidiary of
the Company (each, a “Non-Employee Director”) who is entitled to receive such cash or equity compensation, unless such Non-Employee Director
declines the receipt of such cash or equity compensation by written notice to the Company. This Program shall remain in effect until it is revised or rescinded by further action of the Board. This Program may be amended, modified or terminated by
the Board at any time in its sole discretion. The terms and conditions of this Program shall supersede any prior cash and/or equity compensation arrangements for service as a member of the Board between the Company and any of its Non-Employee Directors. No Non-Employee Director shall have any rights hereunder, except with respect to stock options granted pursuant to the Program. 

1.    Cash Compensation. 

(a)    Annual Retainers. Each Non-Employee Director shall be eligible to
receive an annual retainer of $40,000 for service on the Board. 
 (b)    Additional Annual Retainers. In
addition, each Non-Employee Director shall receive the following additional annual retainers, as applicable: 

(i)    Lead Independent Director. A Non-Employee Director serving as the
lead independent director of the Board shall receive an additional annual retainer of $20,000 for such service. 

(ii)    Audit Committee. A Non-Employee Director serving as Chairperson of
the Audit Committee shall receive an additional annual retainer of $15,000 for such service. A Non-Employee Director serving as a member of the Audit Committee (other than the Chairperson) shall receive an
additional annual retainer of $7,500 for such service. 
 (iii)    Compensation Committee. A Non-Employee Director serving as Chairperson of the Compensation Committee shall receive an additional annual retainer of $10,000 for such service. A Non-Employee Director
serving as a member of the Compensation Committee (other than the Chairperson) shall receive an additional annual retainer of $5,000 for such service. 

(iv)     Nominating and Corporate Governance Committee. A Non-Employee
Director serving as Chairperson of the Nominating and Corporate Governance Committee shall receive an additional annual retainer of $7,500 for such service. A Non-Employee Director serving as a member of the
Nominating and Corporate Governance Committee (other than the Chairperson) shall receive an additional annual retainer of $3,500 for such service. 

(c)    Payment of Retainers. The annual retainers described in Sections 1(a) and 1(b) shall be earned on a
quarterly basis based on a calendar quarter and shall be paid by the Company in arrears not later than the fifteenth day following the end of each calendar quarter. In the event a Non- 







 
Employee Director does not serve as a Non-Employee Director, or in the applicable positions described in Section 1(b), for an entire calendar quarter, the
retainer paid to such Non-Employee Director shall be prorated for the portion of such calendar quarter actually served as a Non-Employee Director, or in such position,
as applicable. 
 2.    Equity Compensation. Non-Employee Directors shall
be granted the equity awards described below. The awards described below shall be granted under and shall be subject to the terms and provisions of the Company’s 2014 Incentive Award Plan, as amended, or any other applicable Company equity
incentive plan then-maintained by the Company (the “Equity Plan”) and shall be granted subject to the execution and delivery of award agreements, including attached exhibits, in substantially the forms previously approved by
the Board. All applicable terms of the Equity Plan apply to this Program as if fully set forth herein, and all grants of stock options hereby are subject in all respects to the terms of the Equity Plan and the applicable award agreement. For the
avoidance of doubt, the share numbers in this Section 2 shall be subject to adjustment as provided in the Equity Plan. 

(a)    Initial Awards. Each Non-Employee Director who is initially elected
or appointed to the Board shall receive an option to purchase 40,000 shares of the Company’s common stock on the date of such initial election or appointment. The awards described in this Section 2(a) shall be referred to as “Initial
Awards.” No Non-Employee Director shall be granted more than one Initial Award. 

(b)    Subsequent Awards. A Non-Employee Director who (i) is serving
on the Board as of the date of each annual meeting of the Company’s stockholders and (ii) will continue to serve as a Non-Employee Director immediately following such meeting, shall be automatically
granted an option to purchase 20,000 shares of the Company’s common stock on the date of such annual meeting. The awards described in this Section 2(b) shall be referred to as “Subsequent Awards.” For the avoidance of
doubt, a Non-Employee Director elected for the first time to the Board at an annual meeting of the Company’s stockholders shall only receive an Initial Award in connection with such election, and shall
not receive any Subsequent Award on the date of such meeting as well. In addition, if a Non-Employee Director’s initial election or appointment does not occur at an annual meeting of the Company’s
stockholders, the number of shares subject to the first Subsequent Award received following such initial election or appointment shall be equal to the product of (i) 20,000 multiplied by (ii) a fraction, the numerator of which equals the number
of calendar months in which service is provided from the date of such election or appointment through the first anniversary of the most recent annual meeting of the Company’s stockholders and the denominator of which equals twelve. 

(c)    Termination of Employment of Employee Directors. Members of the Board who are employees of the Company or
any parent or subsidiary of the Company who subsequently terminate their employment with the Company and any parent or subsidiary of the Company and remain on the Board will not receive an Initial Award pursuant to Section 2(a) above, but to the
extent that they are otherwise entitled, will receive, after termination from employment with the Company and any parent or subsidiary of the Company, Subsequent Awards as described in Section 2(b) above. 

(d)    Terms of Awards Granted to Non-Employee Directors 

(i)    Purchase Price. The per share exercise price of each option granted to a
Non-Employee Director shall equal the Fair Market Value (as defined in the Equity Plan) of a share of common stock on the date the option is granted. 

(ii)    Vesting. Each Initial Award shall vest and become exercisable over three years, with one-third of the shares subject to the Initial Award vesting on the first anniversary of the 







 
date of grant and the remaining shares subject to the Initial Award vesting in twenty-four equal monthly installments over the two years thereafter, such that each Initial Award shall be 100%
vested on the third anniversary of the date of grant, subject to the Non-Employee Director continuing in service on the Board through each such vesting date. Each Subsequent Award shall vest and/or become
exercisable on the first to occur of (A) the first anniversary of the date of grant or (B) the next occurring annual meeting of the Company’s stockholders, subject to the Non-Employee Director
continuing in service on the Board through such vesting date. Unless the Board otherwise determines, no portion of an Initial Award or Subsequent Award which is unvested and/or unexercisable at the time of a
Non-Employee Director’s termination of service on the Board shall become vested and/or exercisable thereafter. All of a Non-Employee Director’s Initial Awards
and Subsequent Awards shall vest in full immediately prior to the occurrence of a Change in Control (as defined in the Equity Plan), to the extent outstanding at such time. 

(iii)    Term. The term of each stock option granted to a Non-Employee
Director shall be ten (10) years from the date the option is granted. 
 3.    Compensation Limits.
Notwithstanding anything to the contrary in this Program, all compensation payable under this Program will be subject to any limits on the maximum amount of Non-Employee Director compensation set forth in the
Equity Plan, as in effect from time to time. 
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