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CONFIDENTIAL        MATERIALS OMITTED AND FILED SEPARATELY WITH        THE

| dated | January                  08th, 2007 |
|-------|-------------------------------------|

| b                  e                  t w e e n | HOLOPACK |
|-------------------------------------------------|----------|

| a                  n                  d | CYTOGEN                  CORPORATION |
|-----------------------------------------|--------------------------------------|

|   | 650                  College Road East |
|--------|----------------------------------------|

|   | Princeton,                  New Jersey 08540 USA |
|--------|--------------------------------------------------|

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**§        1              **
**Purpose        and Subject of this Agreement**

**§        2      **
**Manufacture        of the Contract Products**

| 1. | SUPPLIER                  agrees with CUSTOMER to manufacture and fill the Contract Products                  listed                  in Appendix 1, with the "bottelpack" process according to the                  manufacturing, quality control, packaging and other directions                  issued by                  CUSTOMER and appended to this Agreement as Appendix 2 and 3 and                  7. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 2. | During                  the manufacture of the Contract Products, SUPPLIER will duly consider                  the                  recognised pharmaceutical rules and applicable legal regulations                  in                  Germany. SUPPLIER acknowledges and agrees that: (i) the Contract                  Products                  are to be distributed in the United States (the “Territory”); and (ii)                  SUPPLIER’s manufacture of the Contract Products shall comply with                  applicable pharmaceutical laws and regulations of the United States,                  including without limitation current good manufacturing practices                  (“cGMP”)                  as promulgated under United States Federal Food, Drug and Cosmetic                  Act. |
|----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 3. | CUSTOMER                  assumes the responsibility for the manufacturing, quality control,                  packaging and other directions supplied by it, including the product                  specifications according to Appendix 2, 3 and 7 of this Agreement,                  and for                  all properties of the Contract Products resulting from CUSTOMER’s                  instructions. The same shall apply in the event SUPPLIER manufactures                  Contract Products according to manufacturing, quality control and                  packaging directions, which have been developed in collaboration                  with                  CUSTOMER. |
|----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 4. | SUPPLIER                  is only responsible for fulfilment of its obligations under this                  contract.                  Besides that CUSTOMER assumes responsibility for the fulfilment                  of its                  obligations as manufacturer according to §3,15                  MPG. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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| 5. | Prices                  and payment conditions shall be according to Appendix                  IX. |
|----|----------------------------------------------------------------------------------------------------|

| 6. | In                  the event that SUPPLIER determines to discontinue the manufacture                  of                  Contract Products, SUPPLIER shall give CUSTOMER prompt notice of                  such                  determination. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

**§        3      **
**Supply        of Starting and Secondary Packaging Materials, Release for        Manufacture**

| 1. | SUPPLIER                  shall provide the starting materials required and the packing materials                  according to Appendix 4. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------|

| 2. | CUSTOMER                  shall provide the starting materials required and the packaging                  materials                  according to Appendix 5 free of charge at the latest [**] prior                  to the                  start of production. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 3. | SUPPLIER                  shall inspect all starting materials, to be provided by it for                  quality                  according to the quality control directions in Appendix 3, and                  shall                  release conforming materials for                  manufacture. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 4. | CUSTOMER                  shall supply SUPPLIER with: (i) certificates of analysis for all                  starting                  materials supplied by CUSTOMER according to Appendix 5, if any;                  (ii)                  releases for manufacture for all starting materials supplied by                  CUSTOMER,                  if any. CUSTOMER shall provide to the SUPPLIER a sufficient amount                  of the                  reference standards required for identity, content and purity tests                  of the                  active substances for the current order                  campaign. |
|----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

**§        4      **
**Documentation,        Samples, Retain Samples, Responsible Persons**

| 1. | SUPPLIER                  will supply to CUSTOMER a report (production protocol or batch                  record) for                  each lot manufactured as the documentation for the authorities,                  containing                  the following: |
|----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | - | the                  description and mode of                  application, |
|--------|---|----------------------------------------------------------------------------|

|   | - | the                  lot identification or inspection number of the starting materials                  used, |
|--------|---|---------------------------------------------------------------------------------------------------------------|

|   | - | the                  manufacturing date and the lot                  number, |
|--------|---|------------------------------------------------------------------------------|

|   | - | a                  statement on the amount of medication manufactured in one lot and                  its                  ingredients during the individual processing                  steps, |
|--------|---|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | - | the                  results of the in-process                  inspections, |
|--------|---|------------------------------------------------------------------------------|

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|   | - | the                  confirmation of proper manufacture according to the manufacturing                  instruction signed with the names of the persons responsible for                  the                  individual processing steps, |
|--------|---|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | - | special                  observations during the                  manufacture, |
|--------|---|--------------------------------------------------------------------------------|

|   | - | information                  on the kind of containers, outer coverings, and other packaging                  materials                  used, and |
|--------|---|----------------------------------------------------------------------------------------------------------------------------------------------------|

|   | - | information                  on the kind and number of lot                  samples. |
|--------|---|--------------------------------------------------------------------------------------|

| 2. | SUPPLIER                  shall have the right to vary the lot size within validated                  parameters.  Any lot size outside of validated parameters shall                  require the written consent of CUSTOMER. SUPPLIER shall file the                  documentation and retain samples of each medication for at least                  [**]                  longer than the expiration date of the contract product or longer                  if                  required by law and                  SUPPLIER shall make such materials available as soon as reasonably                  practicable to CUSTOMER after SUPPLIER’s receipt of CUSTOMER’s written                  request for access to such records                  and/or                  samples. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 3. | SUPPLIER                  will furnish to CUSTOMER a summary of all the data in the manufacturing                  protocol which is required to evaluate the contract product (according                  to                  Appendix 6). |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 4. | The                  responsible persons are listed in Appendix 8.  Such responsible                  persons will coordinate work carried out hereunder with the other                  party’s                  responsible persons.  The responsible persons of the respective                  parties shall be the day-to-day contacts between the parties hereto                  and                  shall receive copies of all written correspondence exchanged between                  the                  parties with respect to the designated work.  In the event                  either party identifies an issue relating to the manufacture, quality,                  delivery, customer service, or the like with respect to contract                  product,                  the applicable responsible persons of each party shall promptly                  confer to                  resolve such issue.  If a responsible person leaves the employ                  of a party, an equally competent, acceptable, responsible person                  shall be                  assigned by such party. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

**§        5      **
**Primary        Packing Materials, Labelling, Packing, Shipping**

| 1. | As                  packing material coming in direct contact with the product manufactured                  by                  SUPPLIER (primary packing material), SUPPLIER will use only materials                  by                  manufacturers which have been accepted in writing by                  CUSTOMER.  SUPPLIER shall conduct an identity check of all                  primary packing material to be used in the packaging of the Contract                  Products.  Such identity check shall be in accordance with the                  quality control directions in Appendix                  3. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 2. | Packing                  of the "Contract Products" is made according to the packing directions                  defined in Appendix 7. CUSTOMER assumes the responsibility for                  the                  suitability of the labelling and packing materials (primary and                  secondary                  packing materials) for packing and labelling of the Contract Products,                  including labels which might be supplied by SUPPLIER. SUPPLIER                  does not                  incur liability for the effect of these materials on the contract                  product. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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| 3. | If                  CUSTOMER requires inspections exceeding the specifications in § 5.1 of                  this Agreement, a separate agreement in writing between the parties                  describing such inspections and cost thereof shall be                  required. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 4. | SUPPLIER                  shall ship and deliver the Contract Products [**].  SUPPLIER                  ’s facility located                  in                  Sulzbach-Laufen/Untergröningen. SUPPLIER                  shall                  arrange and organize shipment on behalf of the CUSTOMER under controlled                  temperature conditions, without prejudice to CUSTOMERS responsibility                  for                  the Transport [**]. |
|----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

**§        6      **
**Quality        Control, Release from Manufacture**

**§        7      **
**Storage**

| 1. | The                  starting materials supplied by CUSTOMER, if any, and the Contract                  Products                  manufactured by SUPPLIER shall be stored by SUPPLIER between [**]                  without                  further protective measures. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 2. | If                  the starting materials or Contract Products cannot be stored properly                  under these conditions or if further storage measures are required,                  especially protective measures, CUSTOMER must inform SUPPLIER to                  this                  effect in writing. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 3. | If                  special storage conditions according to § 7.2 of this Agreement require                  additional investment, e. g. air conditioning, external storage                  etc.,                  CUSTOMER will cover the reasonable costs incurred by SUPPLIER in                  connection therewith. |
|----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

**§        8      **
**Marketing        of the Contract Product**

| 1. | CUSTOMER                  shall market the Contract Products on its own                  behalf. |
|----|--------------------------------------------------------------------------------------------------|

| 2. | CUSTOMER                  assumes the responsibility for the selling of the Contract Products                  including the labelling thereof, including without limitation supplements                  to packing, instruction sheets, and                  labels. |
|----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 3. | CUSTOMER                  is the responsible person for putting on the market (as contemplated                  by §                  5 MPG) and is further responsible for obtaining the right to affix                  the                  CE-mark and shall be responsible for the manner of use of the                  CE-mark. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 4. | CUSTOMER                  shall have the appropriate qualified personnel in accordance with§§ 30                  and 31 MPG. |
|----|-----------------------------------------------------------------------------------------------------------------------------------------|

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**§        9      **
**Confidentiality**

|   | a. | was                  already known to the Recipient at the time of disclosure and was                  not                  acquired directly or indirectly from the Discloser or any of its                  Affiliates or from any other Party in breach of an agreement of                  confidentiality to the Discloser or any of its                  Affiliates; |
|--------|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | b. | at                  the time of disclosure was generally known or easily                  accessible; |
|--------|----|-------------------------------------------------------------------------------------------------------|

|   | c. | after                  the time of disclosure became generally known or easily accessible,                  except                  by breach of this Agreement or by breach by any third party being                  under an                  obligation of confidentiality to the Discloser or any of its                  Affiliates; |
|--------|----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | d. | is                  disclosed to the Recipient by a third party and was not acquired                  directly                  or indirectly from the Discloser or its Affiliates or from any                  other party                  in breach of an agreement of confidentiality to Discloser or any                  of its                  Affiliates; or |
|--------|----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | e. | information,                  which is or was developed by the Recipient independently of receipt                  hereunder; |
|--------|----|-------------------------------------------------------------------------------------------------------------------------------|

|   | f. | Information                  expressly marked by the Discloser as non                  confidential. |
|--------|----|------------------------------------------------------------------------------------------------------|

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**§        10    **
**Complaints**

| 1. | SUPPLIER                  shall manufacture and fill the Contract Products listed in Appendix                  1,                  with the [**] process according to the manufacturing, quality                  control, packaging and other directions issued by CUSTOMER and                  appended to                  this Agreement as Appendix 2 and 3 and                  7. |
|----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 2. | CUSTOMER                  is obligated to inspect the Contract Products promptly upon receipt                  and to                  present complaints to SUPPLIER without delay in writing, stating                  the                  reasons as well as the invoice, order, and lot                  numbers. |
|----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 3. | The                  limitation period for all claims related to defects of the Contract                  Products is [**], beginning with delivery of the Contract Products.                  Statements on minimum expiry dates are based on stability experiments                  of                  CUSTOMER and have no influence on the warranty period, and especially                  do                  not extend it. |
|----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 4. | If                  SUPPLIER has manufactured faulty Contract Products                  [**]. |
|----|-----------------------------------------------------------------------------------------------|

**§        11    **
**Liability**

| 1. | SUPPLIER                  is liable to CUSTOMER                  for [**]. |
|----|---------------------------------------------------------------------------------|

| 2. | SUPPLIER                  has concluded a company liability insurance covering personal damages                  up                  to [**], with maximum coverage for a single incidence.                  [**]. |
|----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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| 3. | The                  limitation of liability under § 11.2 shall not apply in cases of [**] of                  the obligations under this                  Agreement. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 4. | If                  third parties claim damages from SUPPLIER, CUSTOMER will indemnify                  and                  hold SUPPLIER harmless from such claims inasmuch as SUPPLIER is                  not liable                  for such damages on the basis of § 11.1 and § 11.3 of this                  agreement. |
|----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 5. | As                  a manufacturer of medical products according to §3,15 MPG, CUSTOMER has                  secured a insurance coverage for product liability with limits                  of [**] (US                  Dollars) and guarantees to maintain this insurance for the duration                  of                  this agreement. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

**§        12    **
**Property,        Insurance, Transport**

| 1. | The                  starting materials and other materials supplied by CUSTOMER remain                  its                  sole property until they are processed by SUPPLIER in the manufacture                  of                  Contract Products. SUPPLIER agrees to inform CUSTOMER without delay                  of                  legal execution against these materials and to inform third parties                  of the                  property rights of CUSTOMER. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 2. | The                  parties agree that SUPPLIER gains co-ownership of the starting                  materials                  and other materials or the contract product by processing the starting                  materials and other materials, to the extent of the value of the                  processing and the starting materials and other materials possibly                  supplied by SUPPLIER in relation to the value of the finished contract                  product. The co-ownership of SUPPLIER remains in force until full                  payment                  of all amounts due SUPPLIER from CUSTOMER hereunder. However, CUSTOMER                  is                  entitled to sell the contract product in the course of its regular                  business operation. |
|----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 3. | CUSTOMER                  is responsible to insure all delivered goods according to Appendix                  5 and                  the manufactured Contract Products, as long as they are at SUPPLIER’s                  premises, against fire, theft and extended coverage                  perils. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 4. | CUSTOMER                  is responsible for suitable transport conditions for the starting                  materials and other materials supplied according to this Agreement,                  and                  the Contract Products manufactured of it by SUPPLIER. The assumption                  of                  further responsibilities by SUPPLIER requires special agreement                  and                  adjustment of costs. |
|----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

**§        13    **
**Further        Storage and Manufacture by CUSTOMER**

| 1. | CUSTOMER                  bears the sole responsibility for proper storage of the products                  in its                  own works or by a third party, once the product has left the premises                  of                  SUPPLIER. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 2. | CUSTOMER                  is responsible for further manufacturing steps that are conducted                  by                  itself or by third persons, after the products have left SUPPLIER’s                  premises. |
|----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 3. | CUSTOMER                  is responsible to insure that the further manufacturing steps do                  not have                  adverse effects to the Contract                  Products. |
|----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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**§        14    **
**Passing        on of Complaints and Product Observations by CUSTOMER**

| 1. | CUSTOMER                  is obligated to inform SUPPLIER without delay of all third party                  complaints with respect to Contract Products manufactured by                  SUPPLIER. |
|----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 2. | The                  obligation to observe the product and the development of scientific                  knowledge, especially according to the rules of product liability,                  is the                  sole responsibility of CUSTOMER. Correspondingly, § 14.1 of this Agreement                  applies to the results of the                  observation. |
|----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 3. | If                  SUPPLIER receives any complaint or report of an adverse event with                  respect                  to Contract Products manufactured for CUSTOMER hereunder from a                  third                  party, such complaint or adverse event report shall be communicated                  in                  writing by SUPPLIER to CUSTOMER within                  [**]. |
|----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

**§        15    **
**Protected        Rights**

**§        16    **
**Inspections**

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**§        17    **
**Legal        Situation Upon Termination of the Agreement**

**§        18    **
**Prohibition        of Transfer**

**§19            **
**Trademarks**

**§        20    **
**Recall**

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**§        21    **
**Final        Provisions**

| 1. | This                  Agreement becomes valid when it has been signed by both parties                  to this                  Agreement. It is concluded for two years and automatically extends                  for one                  year unless one party terminates this Agreement giving 3 months                  notice to                  the end of the first or to the end of any subsequent validity periods                  by                  registered letter. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 2. | Each                  party shall have the right to terminate this Agreement on written                  notice                  to the other party, if the other party breaches a material term                  of this                  Agreement and if breaching party fails to remedy the breach within                  [**] of                  receiving written notice of the                  breach. |
|----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 3. | Amendments                  and supplements to this Agreement and its appendices can be made                  only in                  mutual agreement and must be set out in                  writing. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 4. | Place                  of settlement for all deliveries and payments is 74429                  Sulzbach-Laufen. |
|----|-----------------------------------------------------------------------------------------------------------------|

| 5. | The                  exclusive jurisdiction for all disputes arising from this contract                  shall                  be with the courts of70173 Stuttgart,                  Germany. |
|----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 6. | If                  individual provisions of this Agreement should be or should become                  invalid, the agreement in its entirety shall remain valid. With                  reference                  to the invalid provisions the parties to this Agreement will endeavour                  to                  replace the invalid provision by a valid provision, resembling                  the                  original, invalid provisions as closely as possible, and which                  fulfil the                  economic purposes of the original, invalid                  provisions. |
|----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | 7. | This                  Agreement shall be subject to German Law, to the exclusion of the                  conflict                  of laws provisions thereof. |
|--------|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 8. | All                  necessary changes regarding this Agreement and the appendices,                  shall be                  documented in Appendix 0. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------|

| 9. | Any                  notice given under this Agreement must be in writing and will be                  deemed                  duly given or made if given to a party personally or sent by registered                  post, mail or facsimile to the address or facsimile number shown                  below: |
|----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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| 10. | The                  rights and obligations contained in § § 4.2, 10, 11.1, 17, 19 20 and 21                  shall survive termination of this Agreement, as will any rights                  to payment                  or other rights or obligations have accrued under this Agreement                  prior to                  termination.  Termination will not affect a party's liability                  by                  reason of any act, default, or occurrence to termination. Section                  9 shall                  survive termination of this Agreement for an additional 5                  years. |
|-----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 11. | A                  party's failure to require another party to comply with any provision                  of                  this Agreement shall not be deemed a waiver of such provision or                  any other                  provision of this Agreement. |
|-----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 12. | Except                  as otherwise expressly provided in this Agreement, each party shall                  pay                  its own expenses and costs incidental to the preparation of this                  Agreement                  and to the consummation of the transactions contemplated                  hereby. |
|-----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 13. | The                  parties shall be deemed to be independent contractors, and this                  Agreement                  shall not be construed to create between SUPPLIER and CUSTOMER                  a                  relationship such as, by way of example only, that of employer-employee,                  principal agent, joint-venturer, co-partners or any similar relationship,                  the existence of which is expressly denied by the parties                  hereto. |
|-----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 14. | This                  Agreement and the Quality Agreement constitute the full, complete,                  final                  and integrated agreement between the parties hereto relating to                  the                  subject matter hereof and supersedes all previous written or oral                  negotiations, commitments, agreements, transactions or understandings                  with                  respect to the subject matter hereof.  Any modification,                  amendment or supplement to this Agreement must be in writing and                  signed by                  authorized representatives of both parties.  In addition to the                  foregoing, in the event of a conflict or inconsistency between                  this                  Agreement and the Quality Agreement, this Agreement shall prevail                  and                  control. |
|-----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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| 15. | Each                  party agrees not to issue any press release or other public statement,                  or                  any communication or response to a third party, whether oral or                  written,                  disclosing the existence of this Agreement or any information or                  activity                  relating to this Agreement without the prior written consent of                  the other                  parties*,* provided however, that neither party will be prevented                  from complying with any duty of disclosure it may have pursuant                  to law or                  governmental regulation, including any international, federal or                  state                  securities laws. |
|-----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 16. | The                  titles and headings herein are for convenience only and shall not                  be used                  to interpret or construe the terms and conditions of this                  Agreement. |
|-----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| 17. | This                  Agreement may be executed in counterparts, each of which shall                  be deemed                  an original, but all of which together shall constitute one and                  the same                  instrument.  The parties expressly agree that signatures                  received via facsimile shall be accepted as                  originals. |
|-----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|   | **Appendices:** |
|--------|-----------------|

| Appendix                    1: | Contract                    Products |
|--------------------------------|--------------------------------------|

| Appendix                    2: | Manufacturing                    directions |
|--------------------------------|---------------------------------------------|

| Appendix                    3: | Quality                    control directions/Product                    Specifications |
|--------------------------------|-----------------------------------------------------------------------------------------|

| Appendix                    4: | Starting                    Material/Packing                    material  Specifications |
|--------------------------------|----------------------------------------------------------------------------------------------------|

|   | -                    Supplied by SUPPLIER - |
|--------|---------------------------------------------|

| Appendix                    5: | Starting                    Material/Packing material                    Specifications |
|--------------------------------|-----------------------------------------------------------------------------------------|

|   | -                    Supplied by CUSTOMER - |
|--------|---------------------------------------------|

| Appendix                    6: | Documentation |
|--------------------------------|---------------|

| Appendix                    7: | Packing                    Directions |
|--------------------------------|---------------------------------------|

| Appendix                    8: | Responsible                    Personnel |
|--------------------------------|------------------------------------------|

| Appendix                    9: | Prices,                    Payment Terms |
|--------------------------------|------------------------------------------|

| Appendix                    0: | Revision                    history |
|--------------------------------|-------------------------------------|

| Princeton,                  New Jersey USA | Sulzbach-Laufen,...... |
|--------------------------------------------|------------------------|

| Cytogen                  Corporation | HOLOPACK |
|--------------------------------------|----------|

| By:                  /s/ Michael D. Becker | By:                  /s/ Hans Weiss |
|--------------------------------------------|-------------------------------------|

|   | Michael                  D. Becker, President | Hans                  Weiss |
|--------|-----------------------------------------------|-----------------------------|

|   | and                  Chief Executive Officer | Managing                  Director |
|--------|----------------------------------------------|------------------------------------|

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**APPENDIX        1**

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**APPENDIX        2**

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**APPENDIX        3**

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**APPENDIX        4**

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**APPENDIX        5**

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**APPENDIX        6**

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**APPENDIX        7**

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**APPENDIX        8**

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**APPENDIX        9**

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**APPENDIX        0**

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