NOVOSTE CORPORATION
                     AMENDED AND RESTATED STOCK OPTION PLAN

Amended and Restated August 20, 1996 and as Amended February ___,
1997

     1. PURPOSE. This Stock Option Plan ("Plan") is established to provide
incentives for selected persons to promote the financial success and progress of
Novoste Corporation ("Company") by granting such persons options to purchase
shares of common stock of the Company.

     2. DEFINITION OF "NON-EMPLOYEE DIRECTOR". As defined by Regulation
240.16b-3 under the Securities Exchange Act of 1934, as amended ("Exchange
Act"), a "Non-Employee Director" is a person not currently an officer of the
Company or a parent or subsidiary, who does not receive compensation either
directly or indirectly as a consultant of the Company (except for an amount not
required to be disclosed under Item 404(a) of Regulation S-K, e.g., not more
than $60,000), does not have an interest in a transaction requiring disclosure
under Item 404(a) of Regulation S-K, and is not engaged in a business
relationship which would require disclosure under Item 404(b) of Regulation S-K
(e.g., where the director has a ten percent or more equity interest in an entity
which makes or receives payments in excess of five percent of the Company's or
that entity's consolidated gross revenues).

     3. ADOPTION OF PLAN; STOCK OPTION AND COMPENSATION COMMITTEE. This Plan
shall be effective on the date that it is adopted by the Stock Option and
Compensation Committee ("Committee") of the Board of Directors of the Company.
The Committee shall at all times be composed only of two or more Non-Employee
Directors. The Committee shall have and may exercise any and all of the powers
relating to the administration of this Plan and the grant of options hereunder
as are set forth herein.

     4.   ADMINISTRATION.

          (a)  This Plan shall be administered by the Committee.

          (b)  The Committee shall have the authority to (i) exercise all of the
               powers granted to it under this Plan, (ii) construe, interpret
               and implement this 


<PAGE>

               Plan and any Grants (as defined below) executed pursuant to
               Section 8 hereof, (iii) prescribe, amend and rescind rules and
               regulations relating to this Plan, (iv) make all determinations
               necessary or advisable in administering this Plan and (v) correct
               any defect, supply any omission and reconcile any inconsistency
               in this Plan.

          (c)  The determination of the Committee on all matters relating to
               this Plan or any Grant shall be final, binding and conclusive.

          (d)  No member of the Committee shall be liable for any action or
               determination made in good faith with respect to this Plan or any
               award thereunder.

     5. TYPES OF OPTIONS AND SHARES. Options granted under this Plan ("Options")
may be either (a) incentive stock options ("ISOs") within the meaning of Section
422 of the Internal Revenue Code of 1986, as amended ("Code"), or (b)
nonqualified stock options ("NQSOs"), as designated at the time of grant. The
shares of stock that may be purchased upon exercise of Options granted under
this Plan ("Shares") are shares of the common stock of the Company.

     6. NUMBER OF SHARES. The maximum number of Shares that may be issued
pursuant to Options granted under this Plan is 2,500,000 Shares. Such number of
Shares shall be subject to adjustment as provided in this Plan. If any Option is
terminated in whole or in part for any reason without being exercised in whole
or in part, the Shares thereby released from such Option shall be available for
purchase under other Options subsequently granted under this Plan. At all times
during the term of this Plan, the Company shall reserve and keep available such
number of Shares as shall be required to satisfy the requirements of outstanding
Options under this Plan.

     7. ELIGIBILITY. Options may be granted only to such employees, officers,
consultants and independent contractors of the Company or any Parent, Subsidiary
or Affiliate of the Company (as defined below) as the Committee shall select
from time to time in its sole discretion ("Optionees"), provided that only
employees of the Company or a Parent or Subsidiary of the Company shall be
eligible to receive ISOs. An Optionee may be granted more than one 


                                       2
<PAGE>

Option under this Plan. As used in this Plan, the following terms shall have the
following meanings:

          (a) "Parent" means any corporation (other than the Company) in an
unbroken chain of corporations ending with the Company, if at the time of the
granting of the Option, each of such corporations other than the Company owns
stock possessing 50% or more of the total combined voting power of all classes
of stock in one of the other corporations in such chain.

          (b) "Subsidiary" means any corporation (other than the Company) in an
unbroken chain of corporations beginning with the Company if, at the time of
granting of the Option, each of the corporations other than the last corporation
in the unbroken chain owns stock possessing 50% or more of the total combined
voting power of all classes of stock in one of the other corporations in such
chain.

          (c) "Affiliate" means any corporation that directly, or indirectly
through one or more intermediaries, controls or is controlled by, or is under
common control with another corporation, where "control" (including the terms
"controlled by" and "under common control with") means the possession, direct or
indirect, of the power to cause the direction of the management and policies of
the corporation, whether through the ownership of voting securities, by contract
or otherwise.

     8. TERMS AND CONDITIONS OF OPTIONS. The Committee shall determine whether
each Option is to be an ISO or a NQSO, the number of Shares for which the Option
shall be granted, the exercise price of the Option, the periods during which the
Option may be exercised, and all other terms and conditions of the Option,
subject to the following terms and conditions:

          (a) Form of Option Grant. Each Option granted under this Plan shall be
evidenced by a written Stock Option Grant ("Grant") in such form (which need not
be the same for each Optionee) as the Committee shall from time to time approve,
which Grant shall comply with and be subject to the terms and conditions of this
Plan.

          (b) Exercise Price. The exercise price of an Option shall be not less
than the Fair Market Value (as defined herein) in 


                                       3
<PAGE>

the case of an ISO, or 85% of the Fair Market Value in the case of a NQSO, of
the Shares at the time that the Option is granted. The term "Fair Market Value"
means the closing sale price for a Share on the immediately preceding trading
date as reported on The Nasdaq National Market or, if no closing sale price
shall have been made on such relevant date, on the next preceding day on which
there was a closing sale price; provided, however, that if no closing sale price
shall have been made within the ten business days preceding such relevant date,
or if deemed appropriate by the Committee for any other reason, the Fair Market
Value of such Shares shall be as determined by the Committee. In no event shall
the Fair Market Value of any Share be less than its par value.

          (c) Exercise Period. Options shall be exercisable within the times or
upon the events determined by the Committee as set forth in the Grant; provided,
however, that no Option shall be exercisable after the expiration of ten years
from the date the Option is granted and is subject to earlier termination in the
event of the death or the voluntary or involuntary termination of the Optionee
as set forth herein; provided, further, that no ISO granted to a Ten Percent
Shareholder (as defined by Section 422 of the Code) shall be exercisable after
the expiration of five years from the date the ISO is granted.

          (d) Limitations on ISOs. The aggregate Fair Market Value (determined
as of the time an Option is granted) of stock with respect to which ISOs are
exercisable for the first time by an Optionee during any calendar year (under
this Plan or under any other incentive stock option plan of the Company or any
Parent or Subsidiary of the Company) shall not exceed $100,000.

          (e) Limitations on ISOs and NQSOs. Notwithstanding anything herein,
the maximum aggregate number of Shares with respect to which Options, whether
ISOs or NQSOs, may be granted to any person or entity eligible therefor under
this Plan within any one calendar year is 100,000 Shares.

          (f) Date of Grant. The date of grant of an Option shall be the date on
which the Committee makes the determination to grant such Option unless
otherwise specified by the Committee. The Grant representing the Option shall be
delivered to the Optionee within a reasonable time after the granting of the
Option.



                                       4
<PAGE>

     9. EXERCISE OF OPTIONS.

          (a) Notice. Options may be exercised only by delivery to the Company
of a written notice and exercise agreement in a form approved by the Committee,
stating the number of Shares being purchased, the restrictions imposed on the
Shares and such representations and agreements regarding the Optionee's
investment intent and access to information as may be required by the Company to
comply with applicable securities laws, together with payment in full of the
exercise price for the number of Shares being purchased.

          (b) Payment. Payment for the Shares may be made (i) in cash, (ii) by
surrender of Shares having a Fair Market Value equal to the exercise price of
the Option or (iii) by any combination of the foregoing where approved by the
Committee in its sole discretion; provided, however, in the event of payment for
the Shares by method (ii) above, the Shares so surrendered, if originally issued
to the Optionee upon exercise of an Option(s) granted by the Company, shall have
been held by the Optionee for more than six months.

          (c) Withholding Taxes. Prior to issuance of the Shares upon exercise
of an Option, the Optionee shall pay or make adequate provision for any federal,
state or local withholding obligations of the Company, if applicable.

          (d) Limitations on Exercise. Notwithstanding the exercise periods set
forth in the Grant, exercise of an Option shall always be subject to the
following limitations:

               (i) An Option shall not be exercisable unless such exercise is in
     compliance with the Securities Act of 1933, as amended ("Securities Act"),
     and all applicable state securities laws, as they are in effect on the date
     of exercise.

               (ii) The Committee may specify a reasonable minimum number of
     Shares that may be purchased on any exercise of an Option, provided that
     such minimum number will not prevent the Optionee from exercising the
     Option for the full number of Shares as to which the Option is then
     exercisable.



                                       5
<PAGE>

     10. DEATH OR VOLUNTARY OR INVOLUNTARY TERMINATION. Should an Optionee die,
become disabled, retire or cease to be employed by or associated with the
Company for any other reason, all Options held by the Optionee shall lapse
immediately following the last day that the Optionee is employed by or
associated with the Company except that should an Optionee die the time during
which the Option may be exercised shall be extended three months for an Optionee
that held ISOs and six months for an Optionee that held NQSOs. In all other
cases the Committee, in its discretion, may extend the time during which the
Option may be exercised; provided, however, the maximum period of an extension
that may be allowed shall be three months for an Optionee that held ISOs and six
months for an Optionee that held NQSOs. During any such extension of the
expiration date by the Committee, the Option may be exercised only for the
number of Shares for which it could have been exercised on such termination
date, subject to any adjustment under Section 12 herein.

     11. PRIVILEGES OF STOCK OWNERSHIP. No Optionee shall have any of the rights
of a shareholder with respect to any Shares subject to an Option until the
Option has been validly exercised. No adjustment shall be made for dividends or
distributions or other rights for which the record date is prior to the date of
exercise, except as provided in this Plan.

     12. ADJUSTMENT OF OPTION SHARES. In the event that the number of
outstanding Shares is changed by a stock dividend, stock split, reverse stock
split, combination, reclassification or similar change in the capital structure
of the Company without consideration, the number of Shares available under this
Plan and the number of Shares subject to outstanding Options and the exercise
price per share of such Options shall be proportionately adjusted, subject to
any required action by the Committee, Board of Directors or shareholders of the
Company and compliance with applicable securities laws; provided, however, that
no certificate or scrip representing fractional shares shall be issued upon
exercise of any Option and any resulting fractions of a Share shall be ignored.

     13. NO OBLIGATION TO EMPLOY. Nothing in this Plan or any Option granted
under this Plan shall confer on any Optionee any right to continue in the employ
of the Company or any Parent, Subsidiary or Affiliate of the Company or limit in
any way the right of the Company or any Parent, Subsidiary or Affiliate of the


                                       6
<PAGE>

Company to terminate the Optionee's employment at any time, with or without
cause.

     14. COMPLIANCE WITH LAWS. The grant of Options and the issuance of Shares
upon exercise of any Options shall be subject to and conditioned upon compliance
with all applicable requirements of law, including without limitation compliance
with the Securities Act, compliance with all applicable state securities laws
and compliance with the requirements of any stock exchange on which the Shares
may be listed. The Company shall be under no obligation to register the Shares
with the Securities and Exchange Commission or to effect compliance with the
Securities Act or with the registration or qualification requirement of any
state securities laws or stock exchange.

     15. RESTRICTIONS ON SHARES. At the discretion of the Committee, the Company
may reserve to itself or its assignee(s) in the Grant (a) a right of first
refusal to purchase any Shares that an Optionee (or a subsequent transferee) may
propose to transfer to a third party and (b) a right to repurchase any or all
Shares held by an Optionee upon the Optionee's termination of employment or
service with the Company or a Parent, Subsidiary or Affiliate of the Company for
any reason within a specified time as determined by the Committee at the time of
grant at (i) the Optionee's original purchase price, (ii) the Fair Market Value
of such Shares as determined by the Committee in good faith or (iii) a price
determined by a provision set forth in the Grant.

     16. CHANGE OF CONTROL. Notwithstanding any contrary terms in the Grant of
Options hereunder, in the event of a Change of Control (as defined herein), all
outstanding Options shall accelerate and become immediately fully exercisable.
For purposes of this Plan, a "Change In Control" shall mean (i) the sale or
other disposition to a person, entity or group (as such term is defined in Rule
13d-5 under the Exchange Act) of 50% or more of the Company's consolidated
assets, (ii) the acquisition of 50% or more of the outstanding Shares by a
person or group (as such term is defined in Rule 13d-5) or (iii) if the majority
of the Company's Board of Directors consists of persons other than Continuing
Directors (as defined herein). The term "Continuing Director" shall mean any
member of the Company's Board of Directors on the effective date of this Plan
and any other member of the Board of Directors who shall be recommended or
elected to succeed or become a Continuing 


                                       7
<PAGE>

Director by a majority of the Continuing Directors who are then members of the
Board of Directors. The aggregate Fair Market Value (determined at the time an
Option is granted) of ISOs which first become exercisable in the year of such
dissolution, liquidation, merger, sale of stock or sale of assets cannot exceed
$100,000. Any remaining accelerated Options shall be NQSOs.

     17. AMENDMENT OR TERMINATION OF PLAN. The Committee may at any time
terminate or amend this Plan in any respect (including, but not limited to, any
form of Grant, agreement or instrument to be executed pursuant to this Plan);
provided, however, that shareholder approval shall be required to be obtained by
the Company if required to comply with the provisions of Section 162(m) of the
Code, or the listed company requirements of The Nasdaq National Market or of a
national securities exchange on which the Shares are traded, or other applicable
provisions of state or federal law or self-regulatory agencies; provided,
further, that no amendment of this Plan may adversely affect any then
outstanding Options or any unexercised portions thereof without the written
consent of the Optionee.

     18. TERM OF PLAN. No Option shall be granted pursuant to this Plan on or
after May 26, 2002, but Options theretofore granted may extend beyond that date
and the terms of this Plan shall continue to apply to such Options and to any
Shares acquired upon exercise thereof.

     19. APPLICABLE LAW. The validity, interpretation and enforcement of this
Plan shall be governed in all respects by the laws of the State of Florida and
the United States of America.

     20. ISSUANCE OF SHARES. The Shares, when issued and paid for pursuant to
the Options granted hereunder, shall be issued as fully paid and non-assessable
Shares.

     21. NON-TRANSFERABILITY OF ISOs. No ISO granted pursuant to the Plan shall
be sold, pledged, assigned, hypothecated, transferred or disposed of in any
manner otherwise than by will or by the laws of descent or distribution and an
ISO may be exercised during the lifetime of the Optionee only by such Optionee.



                                       8
<PAGE>

     22. TRANSFERABILITY OF NQSOs. A NQSO may be sold, pledged, assigned,
hypothecated, transferred or disposed of as determined by the Committee and as
set forth in a Grant with an Optionee.



                                       9
<PAGE>

                           [TO BE TYPED ON LETTERHEAD
                             OF NOVOSTE CORPORATION]


                          INCENTIVE STOCK OPTION AWARD


            Date of Grant                 [DATE]

            Recipient                     [NAME]

            Number of Shares              [NUMBER]

            Purchase Price
              per Share                   [PRICE-PER-SHARE]

            Total Purchase
              Price                       [NUMBER] x [PRICE-PER-SHARE]


Dear [NAME]:

We are pleased to inform you that, as a key employee of Novoste Corporation, you
are hereby granted an option to purchase shares of Novoste Common Stock, par
value $.01 per share, in the amount and at the price per share stated above.
This option is granted pursuant to the Novoste Corporation Amended and Restated
Stock Option Plan, a copy of which is attached. This option is exercisable for a
period of ten years from the date of the grant as stated above.

The right to exercise your option will vest per the following schedule:

From the date of the            No part of the option grant shall vest
grant for one year


<PAGE>

More than one but less          25% of the option grant shall vest
than two years after
the date of the grant

More than two but less          50% of the option grant shall vest
than three years after
the date of the grant

More than three but             75% of the option grant shall vest
less than four years
after the date of the
grant

More than four years            100% of the option grant shall vest
after the date of the
grant

You may purchase all shares that are vested at any time prior to the expiration
of the option by delivering full payment to the Corporate Secretary. You may
purchase all or part of the shares which are vested; however, you may not make
partial purchases in increments of less than 100 shares.

This option cannot be sold, pledged, assigned, hypothecated, transferred or
disposed of in any manner other than by will or by the laws of descent and
distribution. Only you may exercise this option during your lifetime.

Sincerely,



Thomas D. Weldon
President and CEO