<PAGE>  1
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 10-K

ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT
OF 1934 FOR THE FISCAL YEAR ENDED DECEMBER 31, 1999

Commission file number  0-28092

Medical Information Technology, Inc.
(Exact Name of Registrant as Specified in Its Charter)

Massachusetts
(State or Other Jurisdiction of Incorporation or Organization)

04-2455639
(I.R.S. Employer Identification No.)

Meditech Circle, Westwood, MA
(Address of Principal Executive Offices)

02090
(Zip Code)

781-821-3000
(Registrant's Telephone Number)

Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days.  Yes [X] No [ ]

The number of shares of Common Stock, $.25 par value, outstanding at December
31, 1999 was 16,457,286
<PAGE>  2
Index to Form 10-K

Part I

    Item 1 - Business                                                   Page 3

    Item 2 - Properties                                                 Page 5

    Item 3 - Legal Proceedings                                          Page 6

    Item 4 - Submission of Matters to a Vote of Security Holders        Page 6

Part II

    Item 5 - Market for Registrant's Common Equity and Related
             Stockholder Matters                                        Page 6

    Item 6 - Selected Financial Data                                    Page 6

    Item 7 - Management's Discussion and Analysis of Financial
             Condition and Results of Operations                        Page 7

    Item 8 - Financial Statements and Supplementary Data                Page 8

    Item 9 - Changes in and Disagreements with Accountants on
             Accounting and Financial Disclosure                        Page 8

Part III

    Item 10 - Directors and Executive Officers of the Registrant        Page 8

    Item 11 - Executive Compensation                                    Page 10

    Item 12 - Security Ownership of Certain Beneficial Owners
              and Management                                            Page 11

    Item 13 - Certain Relationships and Related Transactions            Page 11

Part IV

    Item 14 - Exhibits, Financial Statement Schedules, and Reports
              on Form 8-K                                               Page 12

    Signatures                                                          Page 12
<PAGE>  3
Part I

    Item 1 - Business

COMPANY OVERVIEW

Medical Information Technology, Inc. (MEDITECH) was founded in 1969 to develop
and market information system software for the hospital industry.  During 1999
combined product and service revenue reached $225 million.  By the year's end
MEDITECH had more than 1,900 employees, almost 1,600 active hospital customers
throughout the U.S., Canada and the U.K., as well as a backlog of almost 100
hospitals waiting implementation.

HOSPITAL SOFTWARE

Initially MEDITECH developed a software product to automate one of the main
hospital departments, the clinical laboratory that performs various diagnostic
tests on blood and urine specimens.  Within a few years, this product became
standardized, thereby requiring minimal adaptation to meet the individual needs
of a typical customer.  MEDITECH extended the concept and developed additional
software products for the rest of a hospital's clinical departments.
Eventually, it moved into the financial area by developing a hospital billing
and accounts receivable product as well as various general accounting products.

Although the individual products could be operated in a stand alone fashion, a
hospital achieved maximum effectiveness when they were used in an integrated
mode, sharing access to the common clinical and financial records of the
hospital.  This concept ultimately led to MEDITECH developing the so-called
hospital information system, a cohesive set of software products designed from
the onset to work in conjunction with the overall operation of the hospital and
to minimize the need for specialized interfaces.

COMPUTER HARDWARE

Software requires extensive computer and communication equipment to function.
In spite of this, MEDITECH continues to be a pure software company, limiting
itself to specifying the aggregate components needed as well as suggesting
typical configurations from certain hardware vendors.  The responsibility is
left to the hospital to purchase the requisite hardware and secure a continuing
source of maintenance service for it.

The hardware components traditionally consist of a small set of central medium-
sized computers and a large set of display terminals and printers distributed
throughout the hospital.  All of these elements are interconnected by means of
a standard high speed communication network.  The computers execute the
software and include large disk subsystems containing the permanent and common
clinical and financial records of the hospital.

Hardware technology evolves rapidly, and the current trend is to replace the
display terminals with desktop and handheld computers, thereby forming a client
server network.  In this mode of operation, the central computers become the
file servers while software is executed locally on the client computer which
makes file requests to the servers.

LICENSED SOFTWARE

MEDITECH requires a customer to sign a standard software license agreement
prior to product delivery, implementation and subsequent service of the
software.  This agreement specifies a front end product fee and a front end
implementation fee both of which are payable over the implementation process,
and a monthly service fee after the site goes live.  In addition to precluding
ownership and restricting transfer, the license mandates the hospital hold
MEDITECH harmless from any liability arising from incorrect operation of the
software.

MEDITECH bases its product fee on the total number of hospital beds that a
customer operates at all of its sites, and sets its implementation fee on the
total number of sites.  Large hospitals pay more than small hospitals, but
incremental fees continue to diminish.  The monthly service fees are always
1% of the product fees.  A typical 250 bed acute care hospital might incur a
$500,000 product fee, $100,000 implementation fee and a $5,000 monthly service
fee. An order is booked and goes into the backlog when a signed software
license and 10% of both front end fees are received.

STAFF ORGANIZATION

MEDITECH is organized into functional units grouped around product development,
sales and marketing, implementation, customer service, accounting and facility
operations.  All MEDITECH staff work in five company owned facilities in the
greater Boston area.

From its inception, MEDITECH utilized communication technology which allowed
much of its business activities to be performed by remote access.  MEDITECH
staff sitting at their desks may access client hospitals, both personnel and
computers.  The need for remote offices is thereby negated.  Although most
customer contact is through the phone, certain of the sales and implementation
staff travel to customer sites.

PRODUCT DEVELOPMENT

Most of the product development staff is working on the incremental evolution
of the current product line, as well as creating a few more new products each
year.  The rest of the staff is developing a set of replacement products
utilizing a new technology.  Approximately every seven years, Meditech
introduces the next generation of products based on the new technology and
gradually updates existing customers.

SALES AND MARKETING

Most of the direct sales staff, organized into regions, concentrate on new
prospects.  In addition, some of the sales staff monitor existing customers to
expose them to Meditech's entire product line.  Marketing activities and
promotion are low key because hospitals are easily identified, finite in number
and generally send an RFP to vendors when they are contemplating the purchase
of a hospital information system.

During the sales process, prospects generally visit MEDITECH to talk to product
specialists and to view product demonstrations.  Thereafter they are encouraged
to visit various MEDITECH customer sites to observe first hand the software in
actual operation and to discuss issues of concern with hospital personnel.

IMPLEMENTATION PROCESS

To ensure a successful implementation, the staff must properly train a core
group of hospital personnel about the operation of the software and how to use
it in their daily activity.  To preclude interruptions from normal hospital
activities, MEDITECH mandates that the hospital personnel come to Boston for
intensive training sessions.

As training proceeds, the implementation staff will customize certain
dictionaries to fit the specific need of the hospital's environment, provide
interfaces to non-MEDITECH systems and to assist the hospital in converting
data from legacy systems.  In addition, the licensed software will be
delivered, installed and tested on the customer's hardware.  MEDITECH will
utilize remote access communication technology to minimize or eliminate the
need to travel.

CUSTOMER SERVICE

Once a hospital goes live, the responsibility of maintaining the customer is
transferred to the service staff.  MEDITECH provides 24 hour a day service
coverage to these customers in order to respond to problem calls.  In addition,
the staff updates customers with new releases of the software products as they
become available.  To ensure the continuing education of the hospital staff,
MEDITECH runs seminars on the use of its products.

COLUMBIA HEALTH CARE

Columbia/HCA owns or operates over 300 hospitals in the U.S., Canada, and the
U.K. and has been MEDITECH's largest customer for some time now.  By the end
of 1998 MEDITECH had completed implementation of clinical systems at all of
their hospitals.  They represented 17% of MEDITECH revenues in 1998 and 9% of
MEDITECH revenues in 1999.

    ITEM 2 - Properties

As of December 31, 1999 the Company owned five facilities containing about
1.1 million square feet of space, all being well maintained Class A properties
in the greater Boston area.  The Company occupies 60% of the space and the
remaining 40% is leased to various tenants.  The Company has adequate space
for its reasonable needs over the next few years.

<PAGE>  6
    ITEM 3 - Legal Proceedings

There are no material pending legal proceedings against the Company, nor were
any initiated during the year 1999.

    ITEM 4 - Submission of Matters to a Vote of Security Holders

None.

PART II

    ITEM 5 - Market for Registrant's Common Equity and Related
             Stockholder Matters

No trading market exists for the Company's Common Stock, and accordingly no
high and low bid information or quotations are available with respect to the
Company's Common Stock.

The Company's Common Stock is subject to right of first refusal restrictions
upon sale, assignment, transfer, pledge or other disposition of any of its
shares.

At December 31, 1999 there were 838 holders of record of its Common Stock and
16,457,286 shares outstanding.

The Company has paid quarterly cash dividends continuously since 1980.
Dividends paid per share in the last five years is set forth under Item 6.

    ITEM 6 - Selected Financial Data
<TABLE>
For the Five Years Ended December 31, 1999 (in thousands where applicable):
<CAPTION>
                                   1995      1996      1997      1998      1999
<S>                            <C>       <C>       <C>       <C>       <C>
Operations:
    Total revenue              $143,721  $167,884  $193,805  $203,813  $225,630
    Operating income             58,513    69,550    78,286    79,583    91,553
    Net profit                   37,085    44,350    50,284    53,281    59,956
    Average shares               15,782    15,863    16,029    16,203    16,392
    Earnings per share            $2.35     $2.80     $3.14     $3.29     $3.66

Financial Position:
   Total assets                  197,998   218,339   263,108   266,600  288,278
   Total liabilities              60,170    55,871    73,577    49,328   41,583
   Shareholders' equity          137,828   162,468   189,531   217,272  246,695
   Shares outstanding             15,831    15,938    16,087    16,266   16,457
   Book value per share            $8.71    $10.19    $11.78    $13.36   $14.99

Other Data:
   Working capital               $47,573   $60,373   $44,911   $59,032  $92,130
   Cash flow from operations      41,443    56,413    62,195    59,788   74,158
   Depreciation                    4,809     6,155     9,084    10,078    7,900
   Cash dividends per share        $1.24     $1.40     $1.68     $1.88    $2.00
</TABLE>
<PAGE>  7
    ITEM 7 - Management's Discussion and Analysis of Financial
             Condition and Results of Operations

Comparison of Fiscal Years ended December 31, 1998 and 1999:

Total revenue increased 11% from $203.8 million in 1998 to $225.6 million in
1999 as a result of increased services provided to both existing and new
customers. Operating expenses increased 8% from $124.2 million in 1998 to
$134.1 million in 1999 due primarily to higher staffing costs associated with
producing increased revenues.  Operating expenses did not grow at the same pace
as revenues due to a disproportionate decrease in depreciation expense in 1999.
Additional depreciation expenses of $3.4 million were absorbed In 1997 and 1998
as a result of one-time adjustments made to unify the varying depreciation
methods in use for book versus tax calculation purposes.  As a result, 1999's
depreciation expense dropped by $2.0 million and 1999 operating income
increased 15% from $79.6 million in 1998 to $91.5 million in 1999.

Other income, net of other expense, increased from $8.5 million in 1998 to $8.6
million in 1999.  Two significant component changes offset each other during
the year.  Interest expense decreased $1.6 million year to year as outstanding
bank debt was paid-down but 1998's results included a gain of $1.4 million
from the redemption and sale of marketable securities while there were no such
gains in 1999.

The Company's effective tax rate remained unchanged at 40% in 1999.

Comparison of Fiscal Years Ended December 31, 1997 and 1998:

1998 Revenue increased 5% to $203.8 million, while 1998 Operating Income
increased only 2% to $79.6 million.  During the year the Company experienced a
decrease in the product revenue attributable to a decline in implementations
for Columbia/HCA.  Staff size was not reduced in response as new orders
requiring future implementations increased significantly during the second half
of the year.  The result of this caused growth in Operating Expenses to exceed
growth in Revenue.  1998 Operating Expenses increased 8% to $124.2M due to a 6%
increase in staff size and a continued moderate increase in employee salaries.

Other Income, net of Other Expense, increased from $6.4 million in 1997 to $8.5
million in 1998 due primarily to an increase of $0.9 million in rental income
and a gain of $1.4 million on redemptions and sales of marketable securities.

The Company's effective tax rate decreased from 41% in 1997 to 40% in 1998.

<PAGE>  8
    ITEM 8 - Financial Statements and Supplementary Data

The Financial Statements are included as part of Exhibit 13 (Annual Report to
Shareholders)
<TABLE>
OPERATING RESULTS BY QUARTER:

For the Two Years Ended December 31, 1999 (in thousands where applicable):
<CAPTION>
                                Mar 31    Jun 30    Sep 30    Dec 31
<S>                            <C>       <C>       <C>       <C>
1998
   Total revenue               $48,493   $48,933   $49,922   $56,465
   Operating income             18,756    18,719    18,855    23,253
   Net profit                   12,137    12,353    12,387    16,404
   Earnings per share             $.75      $.76      $.77     $1.01
1999
   Total revenue               $54,456   $57,366   $56,472   $57,334
   Operating income             21,709    23,496    23,020    23,328
   Net profit                   13,915    15,354    15,272    15,415
   Earnings per share             $.85      $.94      $.93      $.94
</TABLE>
    ITEM 9 - Changes in and Disagreements with Accountants on
             Accounting and Financial Disclosure

None.

PART III

    ITEM 10 - Directors and Executive Officers of the Registrant

The positions held by each Director and Officer of the Company are shown below.
There are no family relationships among the following persons.

Name of Director or Officer    Age    Position with the Company

A. Neil Pappalardo              57    Chief Executive Officer, Chairman of
                                      the Board and Director
Lawrence A. Polimeno            58    Chief Operating Officer, President and
                                      Director
Roland L. Driscoll              70    Director
Jerome H. Grossman              60    Director
Edward B. Roberts               64    Director
Morton E. Ruderman              63    Director
L.P. Dan Valente                69    Director
Howard Messing                  47    Executive Vice President
Barbara A. Manzolillo           47    Chief Financial Officer, Treasurer and
                                      Assistant Clerk
Roberta E. Grigg                56    Senior Vice President
Edward G. Pisinski              56    Senior Vice President
Christopher J. Anschuetz        47    Vice President
Robert S. Gale                  53    Vice President
Steven B. Koretz                47    Vice President
Stuart N. Lefthes               46    Vice President
Joanne Wood                     46    Vice President
Jane E. Currier                 47    Chief Corporate Counsel and Clerk
<PAGE>  9
All Directors are elected each year at the annual meeting of shareholders.  All
Officers are elected at the first meeting of the Board following the annual
meeting of shareholders and hold office for one year.  The Board of Directors
has an Audit Committee, an Executive Compensation Committee, and a Charitable
Contribution Committee.

The following is a description of the business experience during the past five
years of each Director and Officer.

A. Neil Pappalardo, founder of the Company, is the Chief Executive Officer and
Chairman of the Board, and has been a Director since 1969.

Lawrence A. Polimeno, the President and Chief Operating Officer, has been a
Director since 1985, and has been with the Company since 1969.

Roland L. Driscoll, retired Chief Financial Officer of the Company, has been
a Director since 1985.

Jerome H. Grossman, Chief Executive Officer of Lion Gate Management Corp., has
been a Director since 1970.

Edward B. Roberts, Professor at Sloan School, Massachusetts Institute of
Technology, has been a Director since 1969.

Morton E. Ruderman, Chief Executive Officer of CRES Development, has been a
Director since 1969.

L.P. Dan Valente, Chief Executive Officer of Palomar Medical Technologies,
Inc., has been a Director since 1972.

Howard Messing has been the Executive Vice President since 1995, was a Vice
President prior to that, and has been with the Company since 1974.

Barbara A. Manzolillo has been the Chief Financial Officer since 1996, was
the Treasurer prior to that, and has been with the Company since 1975.

Roberta E. Grigg has been a Senior Vice President since 1997, was a Vice
President prior to that, and has been with the Company since 1975.

Edward G. Pisinski has been a Senior Vice President since 1997, was a Vice
President prior to that, and has been with the Company since 1973.

Christopher J. Anschuetz has been a Vice President since 1995, was a Senior
Manager prior to that, and has been with the Company since 1975.

Robert S. Gale has been a Vice President since 1995, was a Senior Manager
prior to that, and has been with the Company since 1976.

Steven B. Koretz has been a Vice President since 1997, was a Senior Manager
prior to that, and has been with the company since 1982.

Stuart N. Lefthes has been a Vice President since 1997, was a Senior Manager
prior to that, and has been with the company since 1983.

Joanne Wood has been a Vice President since 1995, was a Senior Manager prior
to that, and has been with the Company since 1983.

Jane E. Currier has been the Chief Corporate Counsel and the Clerk since
1986, and has been with the Company since 1983.
<PAGE> 10
There were no failures to file or late filings under Section 16(a)

   ITEM 11 - Executive Compensation

The following table sets forth the compensation received by the Company's Chief
Executive Officer and the four most highly compensated other Officers for the
three fiscal years ended December 31, 1997, 1998 and 1999.

SUMMARY COMPENSATION TABLE

Name and Position           Year        Salary      Bonus       Other

A. Neil Pappalardo          1999      $360,000   $800,455           0
  Chairman and Chief        1998       360,000    725,345           0
  Executive Officer         1997       360,000    727,676           0

Lawrence A. Polimeno        1999      $240,000   $675,455      $5,811
  President and Chief       1998       240,000    625,345       5,816
  Operating Officer         1997       240,000    627,676       6,042

Howard Messing              1999      $216,000   $425,455      $5,811
  Executive Vice President  1998       180,000    375,345       5,816
                            1997       180,000    377,676       6,042

Edward G. Pisinski          1999      $192,000   $325,455      $5,811
  Senior Vice President     1998       156,000    300,345       5,816
  Sales and Marketing       1997       156,000    302,676       6,042

Barbara A. Manzolillo       1999      $180,000   $275,455      $5,811
  Chief Financial Officer   1998       144,000    225,345       5,816
  and Treasurer             1997       144,000    227,676       6,042

Compensation of Executive Officers:  There are no employment contracts or
agreements in effect for any officer of the Company.  The Board of Directors
annually sets the total amount to be allocated in the General Bonus Program
instituted for the recognition of services rendered by all officers and
employees.  In addition, the Board of Directors annually sets the total amount
to be allocated in the Officer Bonus Program instituted for the recognition
of services rendered exclusively by the officers.  Finally, the Executive
Compensation Committee, composed of Mr. Roberts and Mr. Ruderman, sets Mr.
Pappalardo's annual salary and individual bonus.

Pension Plan:  The Company maintains a qualified defined contribution plan for
all employees known as the Medical Information Technology, Inc. Profit Sharing
Plan.  All employees of the Company who have completed one year of service
participate in the Plan.  The Board of Directors sets the annual contribution
which is allocated in proportion to total compensation (capped at $100,000) of
all eligible members for the Plan year.  No allocation is allowable under this
Plan to owners of 10% or more of the Company's common stock.  Contributions by
members are not permitted.  Benefits under the plan become fully vested after
five years of continuous service with the Company.  Lump sum cash payment is
made upon retirement, death, disability, financial hardship or termination of
employment.

Compensation of Directors:  The members of the Board of Directors who are not
Officers of the Company currently receive a fee of $7,000 for each fully
attended quarterly meeting, with such fee being deemed to also cover any
incidental expenses or directorial conference or committee time expended by
such directors in behalf of the Company during the year.
<PAGE> 11
    ITEM 12 - Security Ownership of Certain Beneficial Owners
              and Management

The following table provides information as of December 31, 1999 with respect
to the shares of Common Stock beneficially owned by each person known by the
Company to own more than 5% of the Company's outstanding Common Stock, each
Director of the Company, each Executive Officer named in the Summary
Compensation Table and by all Directors and Officers of the Company as a
group.  The number of shares beneficially owned is determined according to
rules of the Securities and Exchange Commission.  Under such rules, a person's
beneficial ownership includes any shares as to which such person has sole or
shared voting power or investment power.

                                    Number of Shares       Percentage
                                    of Common Stock        of Shares of
Name                                Beneficially Owned     Common Stock

A. Neil Pappalardo                     4,335,000               26.34%
Morton E. Ruderman                     2,207,919               13.42%
Curtis W. Marble                       1,865,052               11.33%
Meditech Profit Sharing Trust          1,605,809                9.76%
Jerome Grossman                          600,675                3.65%
Lawrence A. Polimeno                     558,563                3.39%
Edward B. Roberts                        360,688                2.19%
Roland L. Driscoll                       264,000                1.60%
Edward G. Pisinski                       147,500                  <1%
Howard Messing                           135,000                  <1%
Barbara A. Manzolillo                     90,000                  <1%
L. P. Dan Valente                         42,500                  <1%
17 Directors and Officers as a Group   8,992,845               54.64%

The address of all Officers and Directors is in care of the Company, MEDITECH
Circle, Westwood, MA 02090.

    ITEM 13 - Certain Relationships and Related Transactions

None.
<PAGE> 12
PART IV

    ITEM 14 - Exhibits, Financial Statement Schedules, and Reports
              on Form 8-K

Exhibit 3i (Articles of Incorporation) and Exhibit 3ii (By-Laws) are
incorporated by reference from the registration statement on Form 10 effective
April 27, 1996 and from exhibit under Item 6 on Form 10-Q for the quarter ended
June 10, 1997 (Amendment to By-Laws), File # 0-28092.

Exhibit 13 (Annual Report to Shareholders) and Exhibit 27 (Financial Data
Schedule) are appended to this document.

There were no reports filed on Form 8-K during the quarter ended December 31,
1999.

    Signatures

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned, thereunto duly authorized.

Medical Information Technology, Inc.
(Registrant)

March 14, 2000
(Date)

Barbara A. Manzolillo, Chief Financial Officer and Treasurer
(Signature)