# '°`~ Global Initiative on High Production Volume (HPV) Chemicals P 

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# Welcome to the Website of th e Global Initiative on High Production Volume (HPV) Chemicals! You will find links to further and related information at the bottom of this page

. Last update

. : June 200 4

What is the ICCA HPV Chemicals Initiative ? The global chemical industry, through the International Council of Chemical Associations (ICCA), launched a global Initiative on High Production Volume (HPV) chemicals at its Board meeting on 3 Oct6ber 1998

. Through this commitment, the chemical industry has undertaken to provide, as a first step, harmonised data sets on the intrinsic hazards of and initial hazard assessments for approximately 1,000 HPV substances by the end of 2004 . The information, i .e . a Screening Information Data Set Dossier (SIDS Dossier), a SIDS Initial Assessment Report (SIAR) and a SIDS Initial Assessment Profile (SIAP), will be submitted to the OECD for international agreement as part of its refocused HPV Chemicals Programme . The cost of generating data and the work to draft the assessments will be borne by industry - and shared, whenever possible, by companies in international consortia

. The main features of the ICCA HPV Chemicals Initiative are : • Voluntary action by the world chemical industry to speed up the process under existing regional and/or global programmes with a clear target date

. • Globally harmonised, internationally agreed data sets and initial hazard assessments under the refocused HPV Chemicals Programme of the OECD

. • Elimination of duplication of testing and assessment efforts

. The main expected benefits are : 

# • to restore public confidence in chemicals and to foster the reputation of the chemical industry on a global basis ; • to produce a sound scientific basis for any subsequent voluntary industry action, global, regional and/or national risk assessment, or legislation ; • to minimise the cost for the industry, an d • to reduce the number of animals for testing

. ICCA believes that a risk assessment is the basis for decisions on how to manage chemicals

. However, experience under the OECD Existing Chemicals Programme has demonstrated that risk assessment is most efficiently carried out on a regional or national level . ICCA has therefore decided to concentrate on the initial hazard assessment as the objective of its Initiative, realising that this is an indispensable input both for the prioritisation of the chemicals subject to risk assessments and for the risk assessment process itself

. In most cases, risk assessment is likely to take place at national or regional level, because of different use situations, regulatory requirements or risk perceptions . However, when international concern is evidenced further consideration of the chemical could be undertaken at the international level . Companies are encouraged to act on their own findings and not wait for regulatory actions

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http ://www .cefic .org/activities/hse/mgt/hpv/hpvinit .htm 1/12/2005

# Global Initiative on High Production Volume (HPV) Chemicals gge 2 of 4

The ICCA HPV Working Lis t To qualify initially for the ICCA Working List of HPV substances, chemicals need to be considered HPV or otherwise of interest in two or more regions (i .e . North America, Europe, or Japan)

. However, chemicals that are HPV in only one region and were sponsored by a company because they believe they ought to be supported by international consortia because, for example , 1 . they have been identified as priority chemicals by national and/or regional authorities and which are HPV chemicals in at least one region ; o r
2 . they are chemicals for which assessments in other programmes had started but got stuck at early stages ; o r 3 . they fit into a category of chemicals that can be assessed together

. The ICCA HPV Working List is reviewed and updated periodically by the ICCA HPV Task Group . The latest main list dated August 2003 contains 1325 chemicals . It also shows which substances have already been assessed by the SIDS Initial Assessment Meeting (SIAM)

. For access to the ICCA Working List please click on ICCA Working List - August 2003 xls

. In contrast with past versions, the revised Working List no longer contains an Annex A . This Annex included HPV chemicals otherwise eligible for the Initiative which already have completed SIDS assessment reports or are undergoing assessments at least as complete under other programmes, particularly risk assessments under the EU Existing Substances Regulation . These chemicals were not eligible for sponsorship under the Initiative . The Annex also included HPV chemicals which were not HPV in at least two regions, but which had been identified as priorities under national programmes or by individual companies . In contrast to the first group, these chemicals are eligible for sponsorship under the Initiative . The ICCA HPV Task Group felt that Annex A created confusion because it included chemicals for a wide variety of reasons, some of which were eligible for sponsorship and others not . The ICCA HPV Task Group will maintain the Annex as an administrative tool for checking eligibility and to respond to questions

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# How does the Initiative work and why should companies participate ? Companies are responsible for collating and generating data for each of the six basic data categories, which have been agreed by the OECD Member countries for screening HPV chemicals for hazardous properties under the OECD's refocused HPV Chemicals Programme . These are : • physical/chemical properties ; • environmental fate ; 

# • ecotoxicity ; • acute toxicity ; • genetic toxicity ; • repeat dose, reproductive and developmental toxicity

. These data will be reported in the OECD's SIDS Dossier forma t The key information from the SIDS Dossier provides a sound basis for the initial hazard assessment of the chemical . The initial hazard assessments will be presented by the industry consortia to a sponsor country in the form of a draft SIAR . The draft SIAR will then be reviewed by the sponsor country and, once approved forwarded to the OECD for consideration and appropriate action at a SIDS Initial Assessment Meeting (SIAM) . The format and content of the SIAR are described in the OECD Guidance Manual (please se e http ://www .oecd .org/document/7/0,2340,en 2649 34379 1947463 1 1 1 1,00 .html )

. The prime responsibility for this Initiative lies with the companies producing HPV chemicals . They collect hazard information and, where required, conduct tests needed to supplement existing

http ://www .cefic .org/activities/hse/mgt/hpv/hpvinit .htm 1/12/2005

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information . To undertake this work, companies either commit to lead the work for a specific substance or category of substances or to co-sponsor the work, through an international consortium . Such consortia are often formed under the auspices of panels or product sector groups of ICCA member associations

. The costs of data gathering, testing and drafting the initial hazard assessment are borne by companies working in the consortia . Depending on the extent to which the required quality data are available, the data generation costs per substance will vary from zero to approximately EUR/USD 400,000 if no data are available at all . Additional costs are incurred for document development and revision . Sharing the burden in consortia and avoiding overlaps in testing saves the chemical industry in excess of EUR/USD 100 million

. Since the same rules apply in Japan, North America and Europe work will have to be carried out only once, avoiding duplication of work and unnecessary animal testing

. Why should companies participate ? 

# Decisions by companies to participate in the ICCA Initiative, either individually or through consortia are voluntary . However, the following is a list of considerations that should lead a company to reach such a decision : 1 . Industry has declared repeatedly its willingness to respond to public concern about chemicals through its Product Stewardship commitments under Responsible Care

. 2 . The chemical industry has an opportunity to take a proactive approach in addressing concerns among the public about chemicals

. 3 . The Initiative will improve our knowledge about chemicals and will enable us to better and faster respond to public concerns

. 4 . The Initiative delivers globally harmonised, internationally agreed data sets and initial hazard assessments which are recognised under national and regional programmes

. 5 . Participation in collection and development of assessment information ensures a role in evaluating that information

. 6 . The Initiative offers a way in which the burden of providing harmonised data and an internationally agreed initial hazard assessment is shared among international producers of a chemical

. 7 . Non-participants in the Initiative may be viewed more unfavourably by the public or by their customers than companies that have chosen to participate

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# 8 . National or regional regulatory action could compel the provision of information foreseen under the Initiative, but with more stringent requirements

. 9 . Governments may attempt to ban or restrict the use of chemicals if there are no adequate data available

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Tracking Progress and Public Access to Information Generate d Confidence and compliance are both tied to the ability of the public to "track" company commitments and progress in the Initiative as it occurs . The ICCA HPV Chemical Tracking System (ICCA TS) is the public's source for monitoring industry progress under the ICCA HPV Chemicals Initiative

. The following elements are being tracked : • Commitments by chemical or category of chemicals , • Commitments by companies or consortia of companies (with members listed), • Statistics on overall commitment s



# http ://www .cefic .org/activities/hse/mgt/hpv/hpvinit .htm 1/12/2005

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ICCA is in the process of making progress indicators available on the ICCA TS . The ICCA Working List already shows for which chemicals the OECD assessment has been completed, but this will have to be supplemented with information about the stage the assessment of the other chemicals has reached

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# For access to the ICCA TS click on http ://www .iccabpv .com I After assessment by the SIAM and endorsement of the assessment by the OECD Joint Meeting information generated by the ICCA HPV Chemicals Initiative will eventually be made available to the public on the United Nations Environment Programme (UNEP) website . The SIAPs are also available on the OECD Integrated HPV Database ( http ://cs3-hq .oecd .org/scripts/hpv/ )

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# Related informatio n

■ ICCA HPV Working List (available in MS Excel ) ■ ICCA (HPV) Chemical Tracking System Web site ■ Contact s 

# ■ Glossary of Acronyms

■ Progres s

■ Establishing and Working in International Consortia

■ Cost-Sharing under the ICCA HPV Initiativ e



# ■ ICCA Initiative - Suggested steps to follow

■ Standard formats and IUCLI D ■ IUCLID Guidance Document ■ List of petroleum products to be excluded from the ICCA Initiative because they are being addressed by another group (MS/Excel 5 .0/7 .0 - 50 Kb ) 

# ■ Usefu l links

http ://www .cefic .org/activities/hse/mgt/hpv/hpvinit .htm 1/12/2005

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ICCA HPV WORKING LIST August 2003 

## ICCA HPV Working List

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► ~tutat'~ 1~25~~ , CAS # Chemical Name assessed at EU US80 US94 JP CAN SIDS Sponsor So rt SIAM [see also http ://cs3- [' written hq .oecd .orglscrtpts/hpv/ procedu re

] for the most recent plctu re 7 50-00-0 formaldehyde 14 x x x x DE 5000 50-01-1 uanidinium chloride x x 50011 56-23-5 carbon tetrachloride x x x x x 5623 56-40-6 I cine x x x 5640 56-81-5 glycerol 14 x x x x x UK 5681 56-84-8 as artic acid x x 56848 57-10-3 palmiticacid x x x x 5710 57-11-4 stearic acid x x x x 5711 57-55-6 ro ane- 1,2 -diol 11 x x x x x US 5755 58-08-2 caffeine 14 x x x DE 5808 58-55-9 theo Iline 13 x x DE 5855 60-12-8 2- hen lethanol x x x x 60128 60-24-2 2-merca toethanol x x x DE 60242 60-29-7 dieth I ether x x x 6029 60•33-3 linoleic acid x x x 6033 62-23-7 4-nitrobenzoic acid x x x 62237 62-54-4 calcium di(acetate) x x 62544 62-56-6 thiourea x x x x 6256 64-17-5 ethanol x x x x x CZ+SL 6417 64-18-6 formic acid x x x x x 64186 64-19-7 acetic acid x x x x x 6419 64-67-5 dieth I sulphate x x x x 6467 65-85-0 benzoic acid 13 x x x x x NL 6585 67-48-1 choline chloride x x x x UK 67481 67-56-1 methanol x x x x x US 67561 67-68-5 dimeth I sulfoxide x x x x 6768 67-72-1 hexachloroethane x x 67721 68-04-2 tri sodium citrate x x x 68042 68-11-1 merca toacetic acid x x x US 68111 68-12-2 N,N-dimeth Iformamide 13 x x x x x DE 68122 69-72-7 salic lic acid x x x x 6972 71-36-3 butan-l-ol 13 x x x x x US 7136 71-41-0 entan-1-ol x x x US 7141 71-55-61,1,1-trichloroethane x x x x x 7155 7482-8 methane x x x x x 7482 74-83-9 bromomethane 13 x x x US 7483 7484-0 ethane x x x x 7484 74-86-2 acet lene x x x x x 74862 7487-3 chloromethane meth 1 chloride 15 x x x x US 7487 74-89-5 meth lamine,solution x x x x x US 7489 74-90-8 hydrogen cyanide x x x 74908 74-93-1 methanethiol x x x US 74931 74-98-6 ro ane li uefied x x x x x 7498 75-00-3 chloroethane x x x x x US 7500 75-014 chloroeth lene 13 x x x x x US 7501 75-04-7 eth lamine x x x US 7504 75-07-0 acetaldehyde x x x x x 7507 75-08-1 ethanethiol x x x JP+US 75081 75-09-2 dichloromethane (methylene chloride x x x x 75092 75-12-7 formamide x x DE 7512 75-15-0 carbon disulphide x x x x x CA 7515 75-18-3 dimeth I sul hide x x x 7518 75-20-7 calcium acet lide x x x x x 7520 75-21-8 ethylene oxide x x x x x CA 7521 75-28-5 isobutane x x x x x 7528 75-31-0 iso ro lamine x x x us 7531 75-35-41,1-dichloroeth lene x x x x 75354 75-36-5 acetyl chloride x x x 7536 75-37-6 1,1-difluoroethane x 7537 75-38-71,1-d'rfluoroeth lene vin lideneflouride 13 x x x US 7538 75-44-5 phosgene x x x 7544 75-50-3 trimeth lamine,solution x x x x x US 7550 75-52-5 nilromethane x x x 7552 75-54-7 dichloro meth I silane x x x FR 7554 75-59-2 methanaminium .N,N,N-t ri meth I-,h droxide x x x 75592 75-649 2- ro anamine, 2-meth I- x x x US 7564 75-65-012-meth I ro an-2-ol x x x x 7565 75-66-1 2-Pro anethiol, 2-meth I- x x JP 75661 75-68-31-chloro-1,l-difluoroethane 12 x x x x FR 7568 75-75-2 methanesul honic acid x x x 7575 75-76-3 silane, tetrameth I- x x US 757 75-77-4 chlorolrimelh Isilane x x x US 7577 75-78-5 dichloro dimeth I silane x x x FR 7578 75-79-6 trichloro meth I silane x x x x FR 7579 75-94-5 trichloro vin I silane x x x US 7594 75-97-8 inacolone x x 75978 75-98-9 pivalic, acid x x x US 759 8

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 1 of 20

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ICCA HPV WORKING LIST August 200 3

CAS fl Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also http ://cs3- [' written hq .oecd .org/scripts/hpv/ procedure) L for the most recent pictur e 77-58-7 dibut Rin dilaurate 7758 77-86-1 1, 3- Pro anediol, 2-amino- 2- h drox meth I x x US 75861 77-92-9 citric acid 11 x x x CH 779291 78-00-21etraeth Head x x x x 78002 78-04-6 dibut Itin maleate US 7804 78-10-4 ethyl silicate Et0 4Si x x US 78104 78-42-21riodt hos hate x 7842 78-51-3 tris 2-butox eth I hos hate x x x 7851 78-59-1 3,5,5-t ri meth I clohex-2-enone 16 x x DE 78591 78-63-7 peroxide, (1,1,4,4-tetramethyftetramethylene) x x US 7863 bisOtert-but I 78-70-61inalool 14 x x x CH 7870 78-78-4 2-meth Ibutane x x x x US 7878 78-79-5 isoprene x x x x US 7879 78-83-1 2-meth ro an-l-cl x x x x x US 78831 78-87-51,2-dichloro ro ane x x x CH 7887 78-92-2 butan-2-ol 14 x x x US 7892 78-95-5 chloroacetone x 7895 78-96-61-amino ro an-2-ol x x US 7896 79-09-4 ro ionic acid x x x EEU-S-E79094 79-14-1 I collic acid x x x 79141 79-21-0 eracetic acid x x x NL 7921 79-22-1 methyl chloroformate x US 79221 79-24-3 ethane, nitro x x 7924 79-31-2 isobut ricacid x x x US 7931 79-3451,1,2,2-tetrachloroethane 15 x x x FR 793451 79-38-9 chlorotri8uoroeth lene 16 x x US 7938 79-39- 0 metha lamide 15 x x JP 79390 79-46-9 2-nitro ro ane x x x 7946 79-77-6 (E)-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2 x 7977
one 80-07-9 bis 4-chio ro hen I sul hone x x x 8007 80-09-1 henol, 4,4'-sulfon Idi- x x x JP 80091 80-10-4 silane, dichlorodi hen I- x x US 801041 80-15-9 al ha,a! a-dimeth Ibenz I h dro eroxide x x x US 8015 80-43- bis al ha,al ha-dimeth Ibenz eroxide x x x x US 8043 80-54-6 2- 4-tert-but Ibenz I ro ionaideh de x x x 8054 80-56-8 in-2 3-ene x x x 80568 81-16-3 2-aminona hthalene-l-sul honiC acid x x x 81163 81-84-5 na hlhaiene- 1 ,8-dicaWox lic anhydride x x x 8184 82-68-8 benzene, entachlaronflro x x 82688 84-61-7 di clohex I hthalate x x x 8461 84-65-1 anthra uinone x x x x 84651 84-66-2 dieth hthalate x x x 84662 84-69-5 diisobut hthalate x x x 8469 85-40-5 1,,, tetrah dro hthalimide x x x 8540 85-41-6 hthalimide x x x x JP 8541 85-42-7 c clohexane-l,2-dicarbox fic anh dride x x x 8542 85-43-8 1,2,3,6-tetrah dro hthalic anhydride x x x 85438 85-44-9 hthalic anhydride x x x x x 8544 87-56-9 mucochloric acid x x x DE 8756 87-90-1 s mcbsene x x x x 87901 88-44-8 4-aminotoiuene-3-sul honic acid 16 x x x x JP 8844 88-53-9 5-amino-2-chlorotoluene-4-sulphonic acid x x x 8853 88-60-6 -m-cresol, 6-tert-but I- 15 x x x JP 88608 88-73-3 1-chloro- 2-nitrobenzene 13 x x x x DE 8873 88-74-4 2-nitroaniline 13 x x x FR 88744 88-75-5 2-nitro henol x x 887 89-78-1 menthol 15 DE 89781 89-87-2 4nitro- m-x lene x x x 89872 90-05-1 uaiacol x x 90051 90-72-2 2,4,6-tris dimeth laminometh ! enol x x US 90722 90-80-2 D lucon o- 1,5-lactane x x x 9080 91-15-6 hthalonitrile 12 x x JP+DE 9115 91-66-7 N,N-dieth laniline x x 9166 91-76-9 hen I-1,3,5-triazine-2,4-di Idiamine 13 x x x JP 9176 92-52-4 bi hen I x x x x 9252 92-84-2 henothiazine x x 92842 93-68-5 o-acetoacetotoluidide 16 x x x JP 9368 93-83-4 oleamide, N,N-bis 2h drox eth I- x x 93834 94-60-0 dimeth c clohexane- 1 ,4-dicarbox late x x x 9460 95-31-8 N-tert-but Ibenzothiazole-2-sul henamide 16 x x x x JP 95318 95-47-6 a lene 16 x x x us 9547 95-49-8 2-chlorotoluene 11 x, x x DE 95498 95-53-4 o-toluidine x x x x 955214 95-545 o- hen lenediamine x x x x us 9554 95-55-6 2-amino henol x x x FR 9555 95-63-6 1,2,4-trimeth Ibenzene x x x US 9563 95-74-9 3-chloro- toluidine x x x 957 95-93-2 1 2 4 5-tetrameth Ibenzene x x 9593 2

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 2 of 20

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ICCA HPV WORKING LIST August 200 3

CAS X Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also h ttp :l/cs3- [' written hq .oecd .orglscrtpts/hpvl procedu re] for the most recent Picture ] 95-9431,2,4,5-tetrachlorobenzene x x 9594 96-05-9 methacrylic acid, all I ester x US 9605 96-10-8 dieth laluminium chloride x x x x 9610 96-18-41,2,3-tri chloro ro ane x x US 9618 96-22-0 entan-3-one x x x 9622 96-23-1 1,3-dichloro- 2- ro anol x 96231 96-24-2 chlo ro ro ane1 ,2-diol x x 96242 96-29-7 butanone oxime x x x x JP+US 9629 96-31-1 1,3-dimeth lurea x x DE 96311 96-33-3 meth t ac late 16 x x x x US 963331 96-48-0 gamma -but ro lactone x x x x 9648 96-76-4 2,4-di-tert-but I henol x x x 9664 97-00-7 1-chloro- 2,4-dinitrobenzene x x x x 9700 97-02-9 2,4-dinitroaniline x x x 9702 97-63-2 methac lic acid, eth I ester x x x JP+US 97632 97-72-3 isobut ric anhydride x x x US 9772 97-74-5 tetrameth Rhiuram monosul hide x x x 9774 97-77-8 disufFiram x x x 97778 97-85-8 isobut isobut rate x x US 97858 97-86-9 isobut I methacrylate x x x JP+US 9786 97-88-1 butyl metha late x x x x JP+US 97881 97-90-5 2-propenoic acid, 2-methyl-, 1,2-ethanediyl ester x x US 9790

9CI 97-93-8 trieth laluminium x x x x 97936 98-00-0 turlu alcohol x 98000 98-07- 7 al ha,al ha,al ha-trichlorototuene x x x 9807 98-13-5 trichloro hen I silane x x x US 9813 98-16-8 al ha,al ha,al ha-tr'rfluoro- m-toluidine x x x -98168 98-52-2 4-tert-but ic clohexanol x x x 98522 98-56-6 4-chlor o- al ha,al ha,al ha-trifluorotoluene x x x IT+US 9856 98-86-2 aceto henone x x x US 98862 98-87-3 al ha,al ha dichlorotoluene x x x 9887 98-88-4 benzo chloride x x x x 9888 98-92-0 nicotinamide 15 x x x CH 9892 98-94-2 Gohe Idimeth lamine x x x us 98942 99-04-7 m-toluic acid 16 x x x JP 99047 99-08-13-nfirotoluene x x x 99081 99-54-7 1,2-dichloro-4-nitrobenzene x x 9954 99-63-8 Iso hthalo I chloride x x 9963 99-75- 2 meth I toluate x x 99752 99-76-3 benzoic acid, h d rox -,meth I ester x x x 9976 99-99-0 4-nitrotoluene x x DE 99990 100-00-51-chloro-4-nftrobenzene 15 x x x x DE 10000 100-0 1-6 4-nitroaniline x x x 10001 100-02-7 4-nitrophenol x x x 10002 100-20- 9 tere hthalo I dichloride x x x 10020 100-29-8 4-nitro henetole x x x 10029 100-37-8 2-dieth laminoethanol 15 x x x DE 100378 100-40 -3 4-vin Ic clohexene x x x 10040 100 51-6 benz alcohol 13 x x x x NL 10051 100-5 4-9 nicotinonitrile x x x US 10054 1007 0-9 2- ridinecarbonitrile x x 10070 101-02-0 tri hen I hos hite x x x 10102 101-54 N 4-amino hen I aniline x x x x 101542 101-81-5 di hen Imethane x 1018 1 101-83-7 dic clohex lamine x x x JP+US 10183 101-84-8 di hen I ether x x x 10184 101-86-0 al ha he Icinnamaldeh de x x x 10186 102-06-71,3-di hen I uanidine 14 x x x x FR 102067 102-09-0 Dip hen Icarbonate DE 10209 102-76-1 triacetin 15 x x x x Jp 102761 102-77-2 2- mor hotinothio benzothi az ote x x x x 102772 102-82-9 tribut lamine x x US 10282 103-09-3 2-eth Ihex I acetate x x US 10309 104-15-4 toluene -4-sul honic acid x x x x 104154 104-55-2 ci nnamaldeh de x x x 104552 104-75-6 hex lamine, 2-ethyl x x us 10475 104-93-8 4-meth lanisole x x x 104938 105-16-8 metha lic acid, 2- dieth lamino eth I ester x x JP 105168 105-39-5 ethyl chbroacetate x x 10539 105-45-3 meth acetoacetate x x x x 10545 105-52-2 maleic acic, bis 1,3-dimeth Ibut I ester x x 105522 105-53-3 diethyl malonate x x x 10553 105-59-9 2,2'-meth liminodiethanol x x x US 10559 105-60-2 e silon-ca rolactam 12 x x x x DE 10560 105-62-4 1-meth 1-1,2-ethanedi I dioleate x~_ __ x x 10562 105-64-6 ero dicarbonic acid, diiso ro I ester x US 10564 106-14-9 Octadecanoic acid, 12-hydroxy -(12- x x 10614

H d rox stearic aei d 106-24-1 eraniol x x x 106241,

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ICCA HPV WORKING LIST August 2003

CAS # Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also h ttp : 11cs3- [' written hq .oecd .orq1scrIpts/hpv/ procedu re ) for the most recent uicturel 106•25-2 nerol x x x 10625 106-31-0 butyric anhydride 16 x x US 10631 106-42-3 x lene 16 x x x x x US 1064 106-43-4 4 chlorotoluene x x x x 1064 106-44-5 cresol 16 x x x x DE 10644 106-49- p-toluidine x x x 106490 106-50-3 p7phenylenediamine x x x US 10650 106-63-8 2- ro enoic acid, 2-meth I ro lester 15 x x us 106638 106-65-0 dimethyl succinate x x x 10665 106- 75-2 ox dieth lene bis chloroformate x x x us 106752 106-88-711,2-e pox butane 11 x x DE 10688 106-89-8 1-chloro- 2,3-e ox ro ane x x x x 106898 106-92-3 propane, 1- all lox -2,3-e ox x 10692 106-93-4 1,2-dibromoethane x x x 10693 4 106-97-8 butane, pure x _X x x x 106978 106-98-9 but-1-ene x x x x x US 10698 107-03-91-Pro anethiol x x JP+US 10703 107-06-21,2-dichloroethane EDC 14115 x x x x x DE 107062 107-15-3 ethylenediamine 13 x x x x US 10715 107-18-6 all I alwhol x x x JP 10718 107-21-1 ethane-1,2-dial x x x x x CA 107211 107-25-5 methyl vinyl ether x x x 10725 107-29-9 acetaldeh de oxime x x 10729 107-31-3 methyl formate x x x US 10731 107-41-5 2-meth entane-2,4-diol 13 x x x UK 1074 1 107-46-0 hexameth Idisiloxane x x x US 10746 107-71-lit-butyl erox acetate x US 107711 107-83-5 _pentane, 2-methyl x x US 1078 107-86-8 3-methyl-2-butenal x 107868 107-88-0 butane-1,3-diol x x x x 10788 107-92-6 butyric acid 16 x x x us 10792 107-96- ro ionic acid, 3-merca t o- meth I ester x x US 10796 107-98-21-methox ro an-2-ol 11 x x x US 10798 108-03-2 1-nitro

-propane x x x 108032 108-11-2 4-meth entan-2-ol x x x x x US 108112 108-18-9 diiso ro lamine x x x us 10818 108-21-4 isopropyl acetate x x x US 10821 108-23-6 isopropyl chloroformate x x US 10823 108-31-6 maleic anh dride x x x x x US 10831 108-32- ro lene carbonate x x x 10832 108-38-3 m-x lene 16 x x x x x US 10838 108-39-4 m-cresol 16 x x x DE 108394 108-45-2 m- hen lenediamine x x US 108452 108-46-3 resorcinol x x x x JP 10846 108-59-8 dimeth malonate x x 108598 108-65-6 2-methox -1-meth leth I acetate 11 x x x x JP 10865 108-67-8 mes' lene x x US 10867 108-68-9 3,5-x lenol x x x 10868 108-77-0 2,4,6-trichloro- 1,3,5-triazine 13 - x x x x CH 10877 108-89-4 4 icoline x x 108894 108-90-7 chlorobenzene x x x x 10890 108-91-8 c clohex lamine x x x x US 108918 108-93- c clohexanol x x x x x 108930 108-98-5 benzenethiol x x x JP 10898 108-99-6 3-picoline x x US 108996 ___j : - 109-06-8 2-meth I ridine x x x x US 109068 109-09-1 pyridine, 2-chlor ox x 109091 109-16-0 trieth lene glycol dimetha late TREGDMA US 10916 109-52-4 valeric acid x x US 109524 109-53-5 isobu vinyl ether x 10953 109-60-4 ro I acetate x x x US 10 109-67-1 nt-l-ene x x x 109671 109-73- but lamine x x x US 10973 109-79-51-Butanethiol x x JP+US 10979 109-831 2-meth laminoethanol x x x US 109831 109-86-4 2-methox ethanol x x x x x CA 109864 109-89-7 dieth lamine x x x x US 10989 109-92- eth I vin I ether x 109922 110-05-4 di-tert-b l e roxide x x x US 11005 110-12-3 2-hexanone 5-meth I x x x 11012 110-15-6 succinic acid x x x x 11015 110-16-7 maleic acid x x x 11016 110-17-8 fumaric acid x x x x 11176 110-19-0 isobu acetate x x x x US 110190 110-30-5 N,N'-eth lenedi stearamide x x x x JP 11030 110-42-9 methyl decanoate x x x 11042 110-44-1 hexa-2,4-dienoic acid x x x x 110441 110-54-3 hexane x x x x x US 11054 110 62-3 n-valeraldeh de x x US 11062 110-64-5 but-2-ene-1 4diol x x x 1106 4

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 As Page 4 of 20

# p . 9

ICCA HPV WORKING LIST August 2003

CAS N Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also http :11cs3- [' written hq .oecd .org/scrtpts/hpv/ procedure] for the most recent atcture l 110-86-1 pyridine x x x US 110861 110-88-3 1,3,5-t ri oxane x x x 11088 110-89-4 i ridine x 1108941 110-91-8 mo holine x x x us 110918 110-93-0 6-meth Ihe -5-en-2-one x 110930 110-941 lutaric acid x x x 110941 110-96-3 diisob lamine x x 11096 110-97-41,1'-iminodi ro an-2-ol x x x 11097 110-98-5,'- di ro an-2-ol 11 x x US 11098 111-11-5 methyl odanoate x x x 11111 111-14- 8 he tanoic acid x x x 11114 111-20-6 Decanedioic acid Sebacis acid x x 1112 111-27-3 hexan-l-ol x x x UK 11127 111-36-4 butane, 1-1 so anoto x x x 111364 111-41-1 2- 2-aminoeth lamino ethanol x x x JP 111411 111-46-6 2,2'-ox diethanol x x x x x CA 11146 111-48-8 ethanol, 2,2'-thiodi x x x DE 11148 111-65-9 octane x x x x us 11165 111-70-6 1-he tanol x x 11706 111-71-7 he tanal x x x 11171 111-82-0 methyl laurate x x x x JP 11182 111-84-2 nonane x x x US 11164 111-86-4 N-oct lamine x US 111864 111-87-5 octan-1-ol x x x It UK 11187 111-88-61-Octanethiol x x JP+US 11188 111-90-0 2- 2-ethox ethox ethanol x x x x US 111900 111-91-1 bis 2-chloroetho methane x x x 111911 111-92-2 dibut lamine x x x US 111922 111-96-6 bis 2-metho eth I ether x x x 111966 112-05-0 nonanoic acid x x x 112050 112-07-2 2-butox eth I a ce tate x x x us 11207 112-15-2 ethanol, 2 2 ethox ethox acetate DGEEA x x US 112152 112-25-4 2-hex lox ethanol x It x US 112254 112-27-6 2,2'-(et h lenediox diethanol x x x x x 11227 112-30-1 decan-1-ol x x x x UK 112301 112-40-3 dodecane x x US 112403 112-42-5 undecanol x x UK 11242 112-55-0 Dode Merca tan x x x 11255 112-57-2 3,6,9-triazaundecameth lenediamine 13 x x x US 11257 112-59-4 ethanol, 2- 2-he lo thox DGHE x x us 112594 112-60-7 3,6,9-tri oxaundecane-1,11-diol x x x 11260 112-62-9 methyl oleate x x x 11262 112-69-6 hexade lamine, N,N-dimeth I x x 11269 112-70-91-iridecanol x x UK 11270 112-72-1 tetradecanol x x x UK 112721 112-75-4 tetrade Icamine, N,N-dimeth I x x 112754 112-80-1 oleic acid x x x x 112801 112-84-5 Z ocos-13-enamide x x x 11284 112-85-6 docosanoic acid 13 x x x JP 11285 112-86-7 Z-docos-l3-enoic acid x x x 11286 112-88-9 octadec-l-ene x x x US 11288 112-90 3 Z octatleo-9-en lamine x x x DE :eu 11290 115-07-1 propene, pure 16 x x x x x UK 115071 115-1D-6 dimeth ether x x x x 11510 115-11-7 2-meth I ro ene x x x x x FR 11511 115-21-9 silane, trichlo ro eth I- x x US 1152191 115-86-6 tri hen hos hate 15 x x x x DE 1158 116-14-3 tetrafluoroeth lene x x x x 11614 116s53-0 2-meth Ibut ric acid x x US 11653 118-48-941-1-3,1-benzoxazine-2,41H-dione x x x 11848 118-58-1 benz salic late x x x 118581 118-79-6 henol, 2,4,6 tribroma x x x x JP 11879 118-82-1 2,2',6,6'-tetra-te rt -but I-4,4'-meth lenedi henol x x x 118821 119-06-2 hthalic acid, dflridec I ester x x x JP 119062 119-36-8 methyl salic late x x x 119368 119-47-1 6,6'-di-te rt -but I-2,2'-meth lenedi- -cresoI 11 x JP 119471 119-61-9 benzo henone x x x 1,9619 119-64-2 1,2,3,4-tetrah drona hthalene x x x 119642 120-51-4 benz benzoate x x 12051 120-80-9 rocatechol x x x FR 12080 120-83-2 2,4-dichloro henol 15 x x x FR 12083 120-92-3 c clo entanone x x FR 12092 121-03-9 4-nitrotoluene-2-sul honic acid x x x x JP 12103 121-44-8 trieth lamine x x x x US 121448 121-57-3 sul hanilic acid x x

___ It 12157 121-69-7 N,N-dimeth laniline x x x US 12169 121-73-31-cltloro-3-nitrobenzene x x 12173 121-82-4perh dro-1,35-trinitro-1,3,5-triazine x x x 12182 121-91-5 iso hthalic acid 14/15' x x x US 1219 1

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 5 of 20

# P . 10

ICCA HPV WORKING LIST August 200 3

CAS tl Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also http :f/cs3- [' written hq .oacd .org/scrlpte/hpvl procedure] for the most recent plctu re l 122-32-7 Olein, tri-(Octadecenoic acid, 1,2,3-propanetriyl) x x 12232

122-40- 7 he tanal, 2- hen Imeth Iene - x x 12240 122-52-1 trieth I phosphite 16 x x x DE 122521 122-99- 6 2- eno ethanol x x US 122996 123-05- 2-eth Ihexanal x x x US 12305 123-28 4 ro ionic acid, 3,3'-thiodi-, diodec I ester x _x 12328 123-30-6 4-amino phenol x x x JP 123308 123-35-3 7-meth I-3-meth leneocta-1,6-diene x x x 12335 123-546 entane-2,4-dione 13 x x x DE 12354 123-62-6 ro rlonic anh dride x x US 12362 123-86-4 n-butyl acetate 13 x x x x US 123864 123-96-6 2-octanol x x UK 12396 123-99-9 Nonaedioic acid Azelaic acid x x 12399 124-04- 9 adi ic acid x x x x x 12404 124-07-2 odanoic acid x x x x 12407 124-10-7 methyl m ristate x x x 12410 124-17-4 2- Z-butox ethox eth I acetate x x x US 12417 124-18-5 decane x x x IT 12418 12422-11-dodecanamine x x 124221 124-28-7 octadec lamine, N,N-dimethyl x x x 12428 124-30-1 octadec lamine x x x DE 124301 124-40-3 dimeth amine, in aqueous solution x x x x x us 12440 124-41-4 sodium methanolate x x x x 12441 12463-0 methanesul hon I chloride x x x 124630 12468-5 2-amino-2-methyl ro anol x x x 12468 124-70-9 silane, diohloroethen Imeth I- x x US 12470 126-33-0 tetrah drothio hene 1,1-dioxide x x x z JP 12633 127-08-2 potassium acetate x x x 127082 127-09-3 sodium acetate x x x x 12709 127-68-4 sodium 3-nitrobenzenesulphonate x x 1276 8 128-04-1 sodium dimeth Idithiocarbamate x x x 126041 128-37-0 2,6-di-te rt

-butyl - cresol 14 x x x x DE 12837 131-11-3 dimeth phthalate x x x x 13111 131-17-9 hthalic acid, diall I ester x x x JP 13117 13420-3 anthranilic acid, methyl ester x x US 13420 136-23-2 zinc bis dibut dithiocarbamate x x x 136232 136-51-6 hexanoic acid, 2-eth I-, calciu m W x x 13651 137-32-6 2-meth butanol x x US 13732 137-40-6 sodium ro ionate x x x 137406 139-33-3 disodium dihydrogen ethylenediaminetetraacetate x x x US 13933
139-89-9 glycine, N-[2-[bis(carboxymethyl)amino)ethylJ-N-(2 x x US 13989

h drox eth I-, trisodium sat 139-96-8 tris 2-h drox eth 1 ammonium dec I sul hate x x x x 139968 140-01-2 pentasodium (carboxylatomethyl)imino x x x x US 140012

bis eth enenitrilo tet r 140-11-4 benz I a ce tate x x x 14011 140-31-8 2- i erazin-l- leth lamine x x x US 140316 140-88-5 ethyl acrylate x x x x US 14088 140-93-2 carbonic acid, dithio-, 0-isopropyl ester, sodium x x x 140932

salt 141-10-616,11 0-dimeth lundeca-3,5,9 trien-2-one x x CH 141106 141-32-2 n-but I acrylate 15 x x x x US 14132 141-43-5 2-aminoethanol x x x x x US 14143 141-53-7 sodium Torrnate x x x x x US 141537 141-78-6 eth I acetate 14 x x x x US 14178 142-16-5 bis 2-eth Ihex I maleate x x x 14216 142-22-3 diall 12,2'-ox dieth I dicarbonate x x x 14222 142-47-2 sodium h dro an lutamate x x 14247 142-73-4 iminodi acetic acid x x 1427 142-78-9 N- 2-h drox eth I dodecanamide x x x 14278 142-82-5 heptane x x x x x US 14282 142-84-7 di ro amine x x x US 14284 142-90-5 dode metha late x x x US 14290 142-91-6 isopropyl almitate x x x 14291 142-96-1 Butyl ether DE 142961 143-07-7 lauric acid x x x x 14307 143-18-0 9-Octadecenoic acid, potassium salt (Oleic acid, x x 14318

otassium sat

t 143-22-6 2- 2- 2-butox ethox ethox ethanol 15 x x x x x US 14322 143-27-1 hexadec lamine x HL- x 143271 143-33-9 sodium cyanide x x x 14333 144-55-8 sodium h d ro encarbonate 15 x x x x BE 144558 144-62-7 oxalic acid x x x x 1446271 149-30-4 benzothiazole-2-thiol x x x x 149304 149 44 0 sodium h drox methanesul hinate x x x x 14944 149-73-5 trimethyl orthoformate x 14973 151-50-8 potassium c anide x x 151508 151-56-4 aziridine x x 1515 6

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 xls Page 6 of 20

# P . 11

ICCA HPV WORKING LIST August 2003

CAS p Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort Ease also http ://cs3• SIAM r written hq .oecd .org/scrtptsRtpvl procedure] for the most recen t icturel 156-62-7 calcium cyanamide, containing more than 25 x x 1`~662

rcent b wei h t 280-57-9 triethylenediamine/ 1,4-diazabicyclo[2 .2 .2]octane x x us 28057

287-92-3 Go ntane x x x US 28792 288-32-4 imidazole DE 2 8832 28888 288-88-0 1,2,4-triaz ole x x 294-62-2 c clododecane x x x 29462 298-12-4 1 ox lic acid x x x x FR 29812 x 29614 298-14-6 tassium h dr encarbonate x 29927 299-27-4 Gluconic acid, mono tassium salt, D299-28-5 Gluconic acid, calcium sak, D- x 29928 301-02-0 oleamide x x x 30102 301-10-0 tin(II) 2-eth Ihexanoate x x US 3011 306-83-2 ethane, 2,2-dichloro- 1,1,1-trifluorox x x 30683
328-847 3,4-dichloro- al ha,al ha,al ha-trifluorotoluene x x x 32884 329-01-1 al ha,al ha,al ha-trrfluoro- 3-tol I isocyanate x x x 32901 1 3332 333-20-0 potassium thioc anate 33448 334-48-5 decanoic acid x x x 393-75-9 4-chloro-3,5-dinitro-alpha,alpha,alpha- x x x 39375

tr'rfluorotoluene 461-58-5 guanidine, c ano x x x JP 46158 473-55-2 2,6,6-trimeth Ibic clo 3 . 1 .1 he tane x x 47355 496-7203' 4-toluenediamine x x US 4967 2

497-19-8 sodium carbonate 15 x x x x BE 497198 501-53-1 formic acid, chloro-, benzyl ester x x US 501531 502-44-3 hexan-6-olide x x x 50244 505-32-8 3,7,11,15-tetrameth Ihexadeo-l-en-3-ol 16 x x CH 505328 505-65-7 1,3-dioxe ane x x 50565 513-35-9 2-meth ]but -2-ene x x x US 51335 513-77-9 barium carbonate, natural x x 51377 515-74-2 sodium sulphanilate x x 515742

526-95-4 D-gluconic acid x x x 526954 527-07-1 luconic acid, monosodium saH, D- x x x JP 527071 528-44-9 trimellHic acid 14115 • x x US 52844 532-32-1 sodium benzoate 13 x x x x NL 532321 538-23-8 Octanoin, tri-(Octanoic acid, 1,2,3-propanetriyl x 538238

ester ; Trica li n 538-93- 2 isobut Ibenzene x x x US 53893 540-69-2 Formic acid, ammonium salt x 540692

540-72-7 sodium thiocyanate x x x 54072
540-841 2,2,4-trimeth I entane x x x US 540841 540-97-6 dodecameth Ic clohexasiloxane x x us 5409 7 541-02-6 c clo entasiloxane, decamethylx x x US 54102

541-05-9 cyclotrisiloxane, hexamethylx US 5410 5 541-41-3 formic acid, chloro- , ethyl ester x us 54141
541-73-1 1,3-dichlorobenzene x x 541731 542-42-7 calcium dipalmitate x x x 544 542-92-71,3,- clo ntadiene x x x 4292 54417-2 calcium diformate x x US 54417 544-63-8 m ristic acid, pure x x x x x ~8
544-76-3 hexadecane x x US 54476 546-68-9 titanium tetraiso ro anolate x x 54668 546-93-0 magnesium carbonate x x 5493 552-30-7 benzene-1,2,4-tricarbox lic acid 1,2-anhydride 14115 x x x x US 55230 553 26 4 i rid I x x x x 5532 555-31-7 aluminum iso ro late x 55531 555-75-9 ethanol, aluminum salts x x 55575
556-67-2 octameth Ic clotetrasiloxane x x x US 7

556-82-1 3-meth Ibut-2-en-l-cl 16 x x x x DE 556821 557-04-0 magnesium stearate x x x 55704 557-05-1 zinc distearate x x x NL :eu 557051

563-47-3 3-chloro- 2-meth I ro ene x x x 56347 576-26-1 2,6-x lenol x x x x US 576261 577-11-7 docusate sodium x x x x 57711 582-25-2 potassium benzoate 13 x x NL 58225 584-08-7 potassium carbonate x x 58408 584-84-9 isoc anic acid, 4meth I-m- hen lene ester x x x us 58484 590-18-1 2-butene, Z x x x 590181 590-29-4 Potassium formate x 59029 593-81-7 trimeth lammonium chloride x x x 59381 593 85-1 di uanidinium carbonate x x 593851 598-56-1 eth Idimeth lamine x x x US 598581 602-01-7 2,3-dinitro toluene x x 60201 603-35-0 tri hen I os hine x x x DE 6033 611-19-8 toluene ,o, .al ha : dichloro- x x x JP 61119 612-83-9 3,3'-dichlorobenzidine dih d ro chloride x x x 61283 614-45-9 benzenecarbo eroxic acid, t-but I ester x x US 61445 616-38-6 dimeth Icarbonate x x IT 61638 616-45-5 2- rrolidone x x 6164 ,

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 7 of 20

# p . 12

ICCA HPV WORKING LIST August 200 3

CAS M Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor soft SIAM [see also http :l/cs3- [' written hq .oacd .org/scdpts/hpv/ procedure] for the most recent picture 624-41-9 1-Methyl Butyl Acetate x x US 62441 624-64-6 2-butene, x x x 62464 624-92-0 dimeth I disulphide x x x 62492 627-83-8 ethylene distearate x x x x 627838 627-93-0 dimeth I adi ate x x x 6279301 628-63-7 Prima Am I Acetate x x US 62863 628-96-6 eth lene dinitrate x x x x 6289661 629-50-5 tridecane x x x US 62950 629-59-4tetradecane x x x IT 629594 629-62-9 ntadecane x x US 62962 629-73-2 hexadeo-l-ene x x x US 629732 629-96-9icosan-1-ol x x x UK 62996 630-08-0 carbon monoxide x x x x x 63008 637-92-3 2-etho -2-meth I ro ane x x 63792 645-62-5 2-eth hex-2-enal x x x 64562 661-19-8 docosan-l-ol x x x UK 661198 674-82-8 but-3-en-3-olide x x x x 67482 675-62-7 silane, dichlo ro meth I 3,3,8-tr'rftuoro ro I- x US 67562 683-18-1 dibut Itin dichloride x x x US 683181 688-84-6 metha lic acid, 2-eth Ihex I ester x x JP+US 68884 693-36-7 o anoic acid, 3,3' 4 hiobis-, dloctadec I ester x x 69336 753-73-1 dimeth in dichloride x x US 753731 760-23-6 3,4-dichloro but-l-ene 11 x x x JP+DE 7602361 760-67-8 2-eth Ihexano I chlo ri de x x x US 760678 763-69-9 ethyl 3-ethoxyp ro ionate x x 7636 764-41-0 1,4-dichlorobut-2-ene x x 76441 770-35-4 2- ro anol, 1- henox - PG hE x US 770354 793-24-8 N-1,3-dimethylbutyl-N'-phenyl-p- x x x x x JP 793248

hen lenediamin e 818-08-6 dibut Itin oxide x x US 81808 818-61-1 2-h dro eth I acrylate x x x x US 818611 822-06-0 hexameth lene diisoc anate 12 x x x DE 82206 822-16-2 Octadecanoic acid, sodium salt (Stearic acid, x x

sodium sat

t 830-13-7 cyclododecanone x x x 83013 839-90 7 Vis 2-h drox eth I-1,3,5 triazinetrione 14 x x x x JP 83990 865-33-8 potassium methanotate 865338 868-77-9 2-h drox eth I metha late 13 x x x x JP 86877 868-85-9 dimeth I hos honate x x x 86885 870-08-6 d' Itin oxide us 87006 872-50-41-meth I-2- rrolidone x x x x us 872504 919-30-2 1- ro anamine, 3- trietho sil I- x x us 919302 919-31-3 ro anenitrile, 3 triethox sil I- x x us 91931 923-26-2 beta-h drox ro I methacrylate JP 923262 924-42-5 N- h dro meth I a lamide x x x 92442 926-57-81,3-dichlo ro but-2-ene x x x 926578 927-07-1 rox ivalic acid, t-but I ester x x US 927071 928-72-3 disodium iminodiacetate x x 92872 929-06-6 2- 2-aminoethox ethanol x x x 92906 947-04-6 dodecane-12-lactam x x x DE 94704 993-16-8 meth Min trichloride x x US 993168 994-05-8 2-methox -2-meth Ibutane x x FINLAND 994058 999-97-3 1,1,1,3,3,3 hexameth Idisilazane x x x US 99997 1002-62-6 Decanoic acid, sodium salt (Capric acid, sodium x 100262

sat t 1002-89-7 Octadecanoic acid, ammonium salt (Stearic acid, x 100289

ammonium sat

t 1066-33-7 ammonium h d ro encarbonate x x x 106633 1066-35-9 sitane, chlorodimeth I- x x US 106635 1067-53-4 2,5,7,10-tetraoxa-6-silaundecane, 6-ethenyl-6-(2- x US 1067534

methox ethax - 1070-00-4 trioct laluminium x x x 1070004 1072-35-1 neutral lead stearate x 1072351 1103-38-4 barium bis[2-1(2- x x x 110338

h d rox na hth I azo na hthelenesul honat e 1115-20-4 3-hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2- x x x lil5204

dimeth I ro ionat 1116-70- tribut laluminium x x x 111670 1118-46 3 but ttin trichloride x US 111846 1119-40-0 dimeth I lutarate x x x 111940 1185-55-3 siiane, trimethox meth I- x x US 118555 1203-17-41,1,2,3,3- entameth tindan x x x 120317 1217-08-9 beta, 1, 1,2,3,3 -hexameth lindan-5-ethanol x x x 121708 1241-94- 7 2 eth Ihex I di hen I hos hate x x x 124194 1300-71- x lenol, re x x 130071 1300-72-7 sodium x lenesul honate x x x 130072 1302-42-7 aluminium sodium dioxide x x x 130242 1305-62-0 calcium dih droxide x x 130562 1305-78-8 calcium o x x x 1305788 1308-38-9 chromic oxide x 821

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 xis Page 8 of 20

# p . 13

ICCA HPV WORKING LIST August 2003

CAS # Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also http ://cs3- [' written hq .oeed .org/scriptslhpv/ procedure] for the most recent picture]
1309-37-1 diiron tri oxide x x x x 1309371
1309-38-2 Ma netite x x 130938 1309-42-8 ma nesium hydroxide x x 130942

-~--- 1309-48-4 ma nesium oxide x x 130948 1310-58-3 13 x x x BE 131058

otassium hydroxide 1310-73-2 sodium hydroxide 14 x x x x PR :eu 1310732 1312-76-1 silicic acid, tassium salt x x DE 1312761 1313-27-5 mol bdenum trioxide x x 13132 1313-82-2 disodium sul hide x x 1313822 1313-99-1 nickel monoxide x x x CA 1313991 1314-41-6 oran e lead x x 131441 1314-56-3 di hos horus ntaoxide x x 131456 1317-36-8 lead monoxide x x x 1317368 1317-38-0 co r oxide x x 131738 1317-39-1 dico er oxide x x x 1317391 1317-42-6 cobalt sulphide x x 131742

1317-60-8 Hematite Fe203 x x 131760 1317-61-9 triiron tetraoxide x x 131761 1318-02-1 zeolites x x 131802 1 131946 1319-46-6 basic lead carbonate 1319-77-3 cresol x x x DE 131977 1321-74-0 divin Ibenzene, pure x x x x JP 132174
1321-94-4 meth Ina hthalene x x x US 1321 1322-98-1 benzenesulfonic acid, c10 dec I, sodium all US 1322981
1323-39-3 Octadecanoic acid, 1 ,2- ro anediol monoester x x 132339 1326-82-5 C .I . Sul hur Black 1 x x 132682 1327-41-9 aluminum chloride, basic x x 132741 1328-53-6 C .I . Pi ment Green 7 x x x x DE 32853 1330-20-7 lene, mixed isomers, pure 16 x x x x x HU 133020
1330-78-5 tricres I hos hate x x x 133078 1331-61-9 benzenesulfonic acid, dodecyl-, ammonium salt x 133161

1333-39-7 In dro benzenesul honic acid x x x 133339 1333-74-0 hydrogen x x x x 133374
1333-86-4 Carbon black x x x 13338 1336-21-6 ammonia, aqueous solution x x x x 133621 1338-23-4 2-butanone, p eroxide x x x US 1338234
1338-39-2 sorbitan laurate x x x 13383921
1341-49-7 ammonium h dro endifluoride x x 134149 1344-00-9 zeolttes x x DE 134400 1344-09-8 silicic acid, sodium salt x x DE 134409
1344-28-1 aluminium oxide x x x 1344281 1344-37-2 C .I . Pi ment Yellow 34 x 1344372 134495-2 silicic acid, calcium salt x x 1344952
1461-22-9 tribut ttin chloride x x US 146122 1461-25-2 tetrabut ttin x x x US 14612 1477-55-0 m- hen lenebis meth lamine 13 x x JP 147755 1490-046 DL-menthol 15 x DE 149004 1559-34-8 3,6,9,12-tetraoxahexadecan-l-ol 15 x x x US 1559348 1562-00-1 sodium 2-h dro ethanesul honate x x x x 1562001 1633-05-2 strontium carbonate x x 1633052 1643-20-5 dodecylamine, N,N-dimethyl-, N-oxide x x x 164320 1653-19-6 2,3-dichlorobuta-1,3-diene x x x 1653196 1675-54-3 2,2'-[(1-methylethylidene)bis(4,1- x x x US 167554

hen leneo meth lene bi s 170462-7 ethanol, 2- 2- dimeth lamino ethox - x US 17 0462 1717-00-6 ethane, 1,1-dichlor o- l-fluoro- 12 x x US 1717006
1724-39-6 c clododecanol x x x 172439 1738-25-6 3-dimeth lamino ro iononttrile x x 173825 1760-24-3 1,2-ethanediamine, N-03-(trimethoxysilyi)propyla- x x US 176024

1761-71-3 4,4'-meth lenebis c clohex lamine x x x US 176171
1762-95-4 ammonium thiocyanate x x 1762954
1843-05-6 odabenzone x x x 184305 1939-36-2 acetic acid, t ri meth lenedinftrilo tetra x US 193936 1984-06-1 octanoic acid, sodium sat x x x 1984061
2050-92-2 di nt lamine x x US 205092 2082-79-3 octadecyl 3-(3,5-di-tert-butyl-4- x x x 208279

h drox hen I ro ionate 2215-35-2 zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) x x x 2215352

bis hos ho rodtth 2216-51-5 L-menthol 15 DE 221651 2235-43-0 phosphonic acid, [nttrilotris (methylene)]tris- x UK 223543

entasodium sal

t 2235-54-3 sulfuric acid, monododecyl ester, ammonium salt x x x x 223554

2403-88-5 2,2,6,6-tetrameth I i eridin-4ol 14 x x JP 240388 2409-55-4 2-te rt -bu I cresol x x 24095 2416-94-6 2,3,6-trimeth I henol x x x 9461
2432-99-7 11-aminoundecanoic acid 15 x x x FR 24329971

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# p . 14

ICCA HPV WORKING LIST August 2003

CAS A Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also http :/lcs3- [' written hq .oscd.org/scApts/hpv/ procedu re ] for the most re cent picture 2437-23-2 Dodecanoic acid, ammonium salt (Lauric acid, x x 243723

ammonium salt) 2439-35-2 2- dimeth lamino eth I acrylate 16 x x x JP 2439352 2451-62-9 s-triazine-2,4,6(l H,3H,5H)-trione,1,3,5-tris(2,3- x x x 245162

e x o I 2487-90-3 silane, trimethox - x x US 248790 2492-26-4 sodium benzothiaz ol-2- sul hide x x x x 2492264 2494-89-5 2-[(p-aminophenyl)sulphonyl]ethyl x x x 249489

h dro ensul hat e 2495-25-2 metha lie acid, tridec 1 ester x us 249525 2495-27-4 metha lic acid, hexade I ester x x US 249527 2524-03-0 0,0-dimeth I hos horochloridothioate x x x us 252403 2524-04-1 0,0-dieth I phosphorochIGridothioste x x x US 2524041 2530-83-8 silane, i ri methox 03 oxiran Imethox ro I a- x x us 2530838 2530-87-2 silane, 3-chloro ro I trimethox - x x us 253087 2549-53-3 metha lic acid, tetradecyl ester x x us 254953 2550-06-3 silane, trichlo ro 3-chloro to I- x x us 255006 2551-62-4 sulphur hexafluoride x x 255162 2587-76-0 tri-n-o ctyftin chloride 258776 2687-25-4 2,3-toluenediamine x x US 2687254 2738-06-9 2-butanamine, N-eth 1-3-methyl- x 273806 2807-30-9 ethylene glycol monopropyl ether (2- x x US 280730

ro o ethano l 280321-4 etid ro nic acid x x x UK 280921 2837-89-0 1 -chloro-1,2,2,2,- tetrafluoroethane (124) 16 x US 2837890 2855-13-2 3 aminometh I 3,5,5 trimeth I clohe lamine x x x DE 285513 2887-47-2 2-dimeth laminoeth I methac late 14 x x x JP 2867472 2893-78-9 troclosene sodium x x x x 289378 2935-90-2 propionic acid, 3-merca to-meth I ester x x US 293590 3006-824 peroxyhexanoic acid, 2-ethyl, tert-but I ester x x x US 300682 3033-62-3 ethylamine, 2,2'-ox bis N,N-dimeth I- x x US 303362 3039-83-6 sodium eth enesul honate x x x BE 303983 3048-64-4 5-vin Inorbom-2-ene x x 3048644 3048-65-5 indene, 3a,4,7,7a-tetrah dro- x x x JP 304865 3085-30-1 1-butanol, aluminum saft x x 3085561- 3091-25-6 mono-n-oct Kin trichloride US 309125 3268-49-3 3 meth fthio ro ionaldeh de x x x DE 326849 3282-30-2 pivaloyl chlori de x x x US 3282302 3290-92-4 2-propenoic acid, 2-methyl-, 2-ethyl-2-(((2-methyl- I x x x US 329092

1-oxo-2-propenyl)oxy)methyl)-1,3-propanediy l ester 3302-10-1 3,5,5-trimeth Ihexanoic acid x x 3302101 3319-31-1 tr is 2-eth Ihe I benzene- 1,2,4-tricarbo late 14 x x x x x JP 3319311 3323-53-3 adipic acid, compound with hexane-1,6-diamine 16 x x x x DE 332353

1 : 1 3332-27-2 Tetradec Idimeth laminoxide 3332272 3425-61-4 t-am I h dro eroxide x US 342561 3452-97-9 3,5 5 -trimeth Ihexan-l-ol 14 x x JP 345297 3542-36-7 di-n-oct Hin dichlo ri de x US 354236 3590-84-9 tetraod Itin x x x US 359084 3622-842 N-but Ibenzenesul honamide x x x 3622842 3646-20-2 diundec I hthalate x x x x 3648202 3687-46-5 dec I oleate x x 368746 3709-43-1 disodium 4,4-dinitrostilbene-2,2'-disul honate x x x 3709431 3779-63-3 (2,4,6-trioxotriazine-1,3,5(2H,4H,6H)- x x x 377963

tri I tris hexameth l e 

### 3965-55-7 isophthalic acid, 5-sulto, 1,3-dimethyl ester, x x 396555

sodium salt 3985-81-7 1-octadecanol, aluminum saft x x 398581 4075 81 4 calcium di ro ionate x x x 407581 4088-22-6 diodadec lamine, N-meth I x x 408822 4098-71-9 3-isacyanatomethyl-3,5,5-trimethylcyclohexyi x x x 409871

iso anate 4170-30-3 crotonaldeh de x x x 417030 4253-34-3 silanet riol, methyl-, triacetate x x US 425334 4300-97-4 ro ano I chloride, 3 chloro-2,2-dimeth I- x x 43009 7

--- ; ~ 4454-05-1 3,4-dih dr o- 2-metho -2H- ran 16 x x x DE 445405 1 4518-98-3disilane,1,1,2,2-tetrachloro- 1,2-dimeth I- x x US 451898 4553-62-2 2-meth I lutaronilrile x x x 4553622 4792-15-8 eth lene glycol x x 4792158 4904-61-4 c clododeca-1,5,9-triene x x x 490461 5039-78-1 [2-(methacryloyloxy)ethyl]trimethylammonium x x x x 5039781

chlorid e 5102-83-0 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'- 16 x x UK 510283

di I bis azo bis N 5124-30-1 4,4'-meth lenedic clohex I diisoc anate x x x 5124301 513 1 5188_07-8 2- ro nol, 1-butox - PGnBE x US 5131668 5188-07-8 Methanethiol, sodium salt x x US 5188078 5216-25-1 al ha,al ha,al ha,4-tetrachlorotoluene x x x 5216251 5324-84-5 1-octanesulfonic acid, sodium salt x x 53248 4

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 10 of 20

# p . 15

ICCA HPV WORKING LIST August 2003

CAS M Chemical Name assessed at EU US90 US94 JP CAN see also http ' r//cs3- So rt SIAM [ [' written hq .oecd .org/scrlpts/hpv/ procedure] for the most recent Icture
5329 14-6 sul hamidic acid x x 532914 5332-73 0 ro lamine, 3 metho - x x US 53327 5421-46-5 acetic acid, merca o- monaammonium salt x x US 542146 5460-09-3 sodium hydrogen 4-amino-5-hydroxynaphthalene- x x x 546009

2,7-disul honat 5567-15-7 2,2'-[(3,3' dichloro[1,1'-biphenyl] 4,4'- 16 x x x x UK 556715

di I bis azo bis N 599461-6 N-(r arboxymethyl)-N-(phosphonomethyl)glycine x x x 599461

5995-42-6 hos honic acid, ndrilotris meth lene tri- x UK 599542 610430-9 N,N"- isobut lidene diurea x x x DE 610430 6140-74-5 methacrylic acid, entadec I ester x US 614074
6258-06-6 sodium 1-amino-4bromo-9,10-dioxoanthracene-2 x x 6258

sulphonate 6358-85-6 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'- 16 x x UK 635885

di I bis azo bis 3 6422-86-2 tere hthalic acid, bis 2-eth Ihex I ester x us 642286

648452-2 ammonium nitrate x x x 6484522 6683-19-8 pentaerythritol tetrakis(3-(3,5-di-tert-butyl-4- x x 6683198

h dro he n 6834-92-0 disodium metasilicate x x x DE 683492 6842-15-5 ro ene, tetramer x x x 684215 6864-37-5 2,2-dimethyl-4,4-methylene bis(cyclohexylamine) 13 x DE 686437

6881-94-3 ethanol, 2- 2- ro o ethox - (DGPE) x x US 688194

6915-15-7 malic acid x x 691515 7336-20-1 disodium 4,4'-diaminostilbene-2,2'-disul honate x x x 7336201 7351-61-3 2-propenoic acid, 2-methyl-,3-(trichlorosilyl)propyl x US 735161

ester 7414-83-7 phosponic aid, (1-hydroxyethylidene)di-, disodium x 741483 V saf

l -09-5 sulphur dioxide x x x 744609 7446 7446-11-9 sulphur trioxide x x x 744611 7446-70-0 aluminium chloride AICI3 x x x 744670 7446-81-3 sodium acrylate x x 744681

7447-40-7 potassium chloride 13 x x NO 744740 7534-94-3 metha lic acid, isobomyl ester x US 753494
7585-41-3 C . I . Pigment Red 48, barium salt (1 :1) x x x 758541
7601-89-0 sodium rchlorate x x 76018 7631-86-9 silicon dioxide, chemically prepared x x 763186

7631-90-5 sodium h dro ensul hite (aqueous solution) x x x 763190 7631-99-4 sodium nitrate, containing in the dry state more x x 763199

than 16,3 p 7632-00-0 sodium nitrite x x 7632000
7646-78-8 tin tetrachloride x x US 7646788 7647-01-0 h dr an chloride 15 x x x x JP 764701 7659-86-1 2-eth Ihe I merca toacetate x x x US 7659661 7664-41-7 ammonia, anh drous x x x x 766441 7664-93-9 sul huric acid 11 x x x x FR 766493 7681-38-1 sodium h dr ensul hate x x 7681381 7681-49-4 sodium fluoride x x 76814 7681-53-0 sodium hos hinate x x 768153 7681-57-4 disodium disulphite 13 x KO 768157
7697-37-2 nRric acid x x x x 769737 7704-349 sulphur, precipitated, sublimed or colloidal x x x 770434 7705-08-0 iron trichloride x x x 770508 7719-09-7 thionyl dichloride x x 771909 7719-12-2 phosphorus trichlori de x x 7719122

7720-78-7 iron sulphate x x x 772078
7727-21-1 di otassium peroxodisulphate x x US 7727211
7727-43-7 barium sulphate, natural x x 772743 7727-54-0 diammonium peroxodisulphate x x US 772754
7757-79-1 potassium nitrate x x 7757791
7757-82-6 sodium sulphate x x x x 775782
7757-83-7 sodium sulphite x x 775783
7758-02-3 potassium b ro mide x x 775802
7758-19-2 sodium chlorite x 7758192 7758-23-8 calcium bis(dihydrogenorthophosphate), with a x x x 7758238

fluorine conte 7758-97-6 chromic acid (H2CrO4), lead 2+ salt 1 :1 x x 775897
7758-98-7 copper sul hate x x x 775898
7761-88-8 silver nitr ate x - x 776188
7772-98-7 sodium thiosul hate x x 777298 7775-09-9 sodium chlorate x x x 777509 7775-14-6 sodium dithionile x x x x DE 777514 7775-27-1 disodium roxodisul hale x x US 7775271 7778-18-9 calcium sul hate, natural x x x x 777818 7778-54-3 calcium h ochlorite x x x JP 777854 7778-80-5 potassium sulphate, containing in the dry state x x 777880

more than 5 2

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# p . 16

ICCA HPV WORKING LIST August 2003

CAS +M Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also hltp ://csSC written hq .oecd .orglscHptslhpvl procedure] for the most recent plOture t 7782-50-5 chlorine 16 x x x IT :eu 778250 7782-78-7 nitro s Isul huric acid x x 778278 7783-06-4 h dro en sul hide x x x x 7783064 7783-18-8 ammonium thiosul hate x x x 7783188 7783-20-2 ammonium sulphate x x x x 7783202 7785-87-7 manganese sulphate x x 778587 7790-94-5 chlorosul huric acid x x 779094 7791-25-5 sul hu I dichloride 15 x x DE 779125 8001-31-8 coconut oil x x x 8001318 8001-78-3 castor oil, hydrogenated x x x 800178 8002-26-4 tall oil x x x 8002264 8002-75-3 oils, palm x x x 800275 8005-02-5 C .I . Solvent Black 7 x x x 800502 8006-64-2 turpentine, oil x x x 8006642 8007-18-9 C. I

. Pigment Yellow 53 15 x x x JP 80071 8 8007-24-7 cashew, nutshell li x x x 800724 8007-45-2 tar, coal x x x 800745 8013-07-8 soybean oil, e oxidized x x x US 801307 8016-11-3 linseed oil, e oxidized x x us 801611 8016-70-4 soybean oil, hydrogenated x x x 8016704 B016-81-7 tall-oil flch x x x 801681 8021-99-6 charcoal, bone x x x 8021996 8023-79-8 oils, palm kernel x x x 8023798 8030-12-4 Tallow, hydrogenated x x x 803012 8032-32-41i ro ine x x x US 803232 8050-09-7 rosin x x x 805009 8050-15-5 resin acids and rosin acids, hydrogenated, Me x x x 805015

esters 8050-26-8 resin acids and rosin acids, esters with x x x 805026

ntae hritol 8050-31-5 resin acids and rosin acids, esters with glycerol x x x 805031
8051-30-7 coconut oil, reaction products with diethanolamine x x x 805130

8052-10 6 tall-oil ro sin x x x 80521106 8052-41-3 Stoddard solvent x x US 805241 8052-48-0 fatt acids, tallow, sodium salts x x x x 805248 9005-90-7 turpentine x x x 900590 908406-4 NaphthalenesuHonic acid, polymer with x 9084664

deh de, sodium sat

t formal 1002497-2 dinit ro en oxide x x 1002497 10025-67-9 disul hur dichloride x x x 1002567 10025-78-2 trichlorosilane x x x US 10025782 10025-87-3 hos ho I trichloride x x 1002587 10026-047 silicon tetrachlo ri de x x US 1002604 10028-22-5 diiron tris sul hate x x 1002822 10035-10-6 hydrogen bromide x x UK 1003510 10043-01-3 aluminium sulphate x x x 1004301 10043-52-4 calcium chloride 15 x x x JP 1004352 10101-39-0 calcium silicate x x 10101390 10117-38-1 potassium Sul hite x x 10117381 10124-43-3 cobalt sulphate x x x 1012443 1012465-9 Dodecanoic acid, potassium sell (Lauric acid, x 1012465

potassium saf

t 10126-68-8 4-he tade lidene-3-hexadec loxetan-2-one UK 10126688 10213-79- silicic acid (H2SiO3), disodium sell, pentahydrate DE 1021379

10584-98-2 dibu Itin bis ( 2 - e t Ihex Imerca toacetate x US 10584982 10595-72-9 ro anoic acid, 3,3'-thiobis-, ditride I ester x x 1059572 11070-44-31etrah drometh I hthalic anh dride 15 x x x x JP 1107044 11071-47-9 isooctene x x 1107147 11084-85- 8 tridecasodium h ochloritetetrakis hos hate x x 11084858 11099-06-2 silicic acid, eth I ester x x US 1109906 11 138-60-6decanoic acid, ester with 2-ethyl-2- x x x 11138606

h drox meth I-1,3 ro anediol odanoat e 12036-76-9 basic lead sul hate 1203676 12042-91-0 dialuminium chloride entah droxide x x 1204291 12065-90-6 tetrabasic lead sul hate x 1206590 12068-03-0 benzenesulfonic acid, meth I-, sodium salt x 1206803 12070-12-1 tun sten carbide x x 12070121 12075-68-2 trieth Idialuminium trichloride x x x 12075682 12125-02-9 ammonium chloride x x JP 1212502 12141-20-7 dibasic lead phosphite x 1214120 12202-17-4 tetralead trioxide sul hate x 1220217 12336-95-7 basic chromium sul hate x 1233695 12578-12-0 dibasic lead stearate 1257812 12656-85-8 C .I . Pi ment Red 104 x 1265685 13048-33-4 hexameth lene dia late x x x 1 US 13048 3 13463-40-6 Dante carbon liron x x x x 1346340

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 12 of 20

# p . 17

ICCA HPV WORKING LIST August 2003

CAS 0 Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also http :1lcs3- r written hq .oecd .orglscriptsfhpvl procedure) for the most recent qictur o 13517-24-3 silicic acid (H2Si03), disodium saR, nonahydrate x DE 1351724

13528-88-6 disilane, 1,1,2-trichloro- 1,2,2-trimeth 1- x x US 1352888 13547-70-1 1-chloro-3,3-dimeth Ibufan-2-one i x x US 13547701 13952-84-6 2-butanamine x US 1395284 1462413-6 1-octanol, aluminum salt x x 1462413 14624-15-8 1-clodecanol, aluminum salt x x 14624158 15214-89-8 2-a lamid o- 2-meth I ro anesul honic acid x x x 1521489 15356-60-2 (+ )-menthol 15 DE 15356602 15831-10-4 m-Cresol, corn . with cresol 2 :1 16 D E 15381104 15571-58-1 di-n-W Kin bis 2-eth Ihex Imerca toacetate x US 15571581 15625-89-5 2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl x x x US 1562589

dia l a 15630-89-4 disodium carbonate, compound with hydrogen x x 15630894

peroxide (2 :3) 15708-41-5 sodium feredetate x x x US 1570841 15827-60-8 [[(phosphonomethyl)imino]bis[ethane-2,1- x x x UK 1582760

d' initrilobis met h 16090-02-1 disodium 4,4'-bis[(4-anilino-6-morpholino-1,3,5- x X x 16090021

triazin-2- I 16111-62-9 e ro dicarbonic acid, bis 2-eth Ihex I ester x x U S 1611162 16219-75-3 5-eth lidene-8,9,10-trinorbom-2-ene 14 x x x x JP 1621975 16291-96-6 charcoal x x x 1629196 16470-24-9 tetrasodium 4,4'-bis[j4-[bis(2-hydroxyethyl)amino]- 13 x x x DE 1647024

6-(4-sul p 16485-47-5 iron (ferric) N-(2- x x US 1648547

hydroxyethyl)ethylenediaminetriacetic aci d ferrate(1-),[N-[2-[bis(carboxymethyl)amino]ethyl)- N-(2-hydroxyethyl)glycinato(3-)]-, sodiu m

16721-80 sodium h dro ensul hide x x x x 1672180 16872-11-0 tetrafluorobori c acid x x 1687211 16883-83-3 benzyl 3-isobutyryloxy-l-isopropyl-2,2- x x x 1688383

dimeth I ro I htha l 16893-85-9 disodium hexafluorosilicate x x 1689385 16919-27-0 di potassium hexafluorotitanate x x 1691927 16961-83-4 hexafluoro silicic acid x x x 16961834 17084-02-5 glycine, N,N'-(1,3-propanediyl)bis[N- 1708402

carbox meth I ,tetrasodium sal t 17095-24-8 tetrasodium 4-amino-5-hydroxy-3,6-bis[[4-[[2- x x x x JP 17095248

sul honatoo 17321-47-0 0 ,0-dimeth I thio hos horamidate x x x 1732147 17689-77-9 silanetriol, eth Itriacetate x x US 1768977 17796-82-6 N- clohex flhio hthalimide x x x x 1779682 17976-43-1 cl o- di-mu-oxo mu- hthalato irilead x x x 17976431 18328-90-0 all lamine, N- ethyl -2-meth 1- x x US 183289001 18479-58-8 2,6-dimeth lod-7-en-2-ol x x 18479588 18719-03-4 a .N, .ka a .0 4- sodium, OC-821 x x US 18719034 19141-82-3 1-hexadecanol, aluminum sell x x 1914182 19910-65-7 di-sec but I e rox dicarbonate x US 1991065 20324-32-7 2-methox meth lethox ro anol DPGME 12 x US 2032432 20324-33-8 tri ro lene I col meth I ether x x US 20324338 20592-85-2 phosphonic acid, [nitrilotris(methylene)tris-sodium x UK 20592852

sell 20642-05-1 Potassium hydrogen formate 20642051 20824-56-0 acetic acid, (ethylenedinftrilo)tetra-,diammonium x x US 2082456

saf t 21265-50-9 ammonium [[N,N'-ethylenebis[N- x x x US 2126550

carbo meth I I cinato 4- 21645-51-2 aluminium h droxide x x 21645512 22042-96-2 [[(phosphonomethyl)imino]bis[(ethylenenitrilo)bis( x x UK 22042962

methyl en e 2113-87-7 methanamine, nitrate x x 2211387 22473-78-5 acetic acid, (ethylenedinitrilo)tetra- x US 2247378 2f ; T

tetraammonium sal

t 22591-21-51,1,-dichloro inacolone x x us 2259121 22984-54-9 2-butanone, O,O',O"- meth Isil lid ne trioxine x x US 2298454 23275-26-5 1-hexanol, aluminum salt x x 2327526 23783-42-8 3,6,9,12-tetraoxotridecanol 15 x x x US 23783428 24488-13-1 2-eth Ihex Ichloroformate x US 24468131 24549-06-2 6 eth I 2-toluidine x x x 2454906 2463461-5 potassium E,E -hexa-2,4-dienoate x x x x 2463461 25013-15-4 vin 1loluene x x x 250131 25013-16-5 bu Ih drox anisol x 2501316 25103-09- isooct I meres toa ce tate x x x US 2510309 25103-58-6 te rt -dodecanethiol x x x x JP+US ; 2510358 25155-23-1 tri len I hos hate x x 25155231 25155-25-3 peroxide, (phenylenediisoproylidene) bisOtert- x x US 2515525

butyl 25155-30-0 sodium dodec ibenzenesul honate pure x x x x x US 2515530

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 13 of 20

# p . 18

ICCA HPV WORKING LIST August 200 3

CAS k Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also http ://cs3- (' writt en hq .oecd .org/serlPtslhPv/
procedu re ] for the most recent pfcturel 2516767 25167-67-3 butane x x x x
25168-05-2 chloro toluene x x x 2516805

25168-24-5 dib Kin S,S'-bis isooct Imerca toacetate x x US 2516824 25264-93-1 hexene x x x US 25264931 25265-71-8 ox di to anol 11 x x x x US 25265718
25321-14-6 dinil ro tcluene x x x x 2532114 25321-41-9 x lenesul honic acid x x x 2532141 25339-17-7 isodec I alcohol x x x 2533917
25339-564 he tene x x x US 253395 25340-17-4 benzene, diethyl- x x x x 2534017 25360-10-5 Tert-Non I Merca an x x JP+US 2536010

25376-45-8 diaminotoluene x x x DE 25376458 25377-73-5 dodecen Isuccinic anh dride x x x x 2537773 25377-83-7 octane x x x us 2537783

25378-22-7 dodecene x x us 2537822 25496-01-9 benzenesulfonic acid tridec I- x x 2549601 25496-72-4 Olein, mono-Octadecenoic acid, 1,2,3- x x 2549672

ro anediol monoester 2yty8491 25498-49-1 [2-(2- x x u s

methox meth lethox meth lethox ro anol 2555014 25550-145 to]uene, ar-eth I- x x x u s
25550-98-5 diisode I hen I phosphite x x 2555098 2558483-2 In dro ro I a late HPA x x us 25584832 25852-70-4 monobut Itin tris is Imerca toacetate x x us 258527
25869-00-5 ammonium iron 3+ hexakis ano-C ferrate 4- x x 2586900 26248-24-8 benzenesulfonic acid, tridec I-, sodium salt x x x us 26248248
26264-O6r2 benzenesulfonic acid, dodecyl-, calcium saft x x x 2626406 26303-548 1-decanol, aluminum saft x x 26303548 26401-86-5 Triisooctyl 2,2',2"- US 264018 6

Istann lid ne tris thio riacetate US 2640197 Oct 26401-97-8 Diisooctyl 2,2'-

di Istann lene bis thio diacetate 2644710 26447-10-9 benzenesulfonic acid, dimethyl-, ammonium salt x x

26471-62-5 m-tol lidene diisoc anate x x x x US 2647162 2654423 0 isode I di hen I phosphite x x x 2654423 26636-01-1 dimeth Kin S,S'-bis isooct Imerca toacetate x x us 26636011
26748-41-4 ero hexanoic acid, 2-eth I-, t-but I ester x x US 2674841
26748-47-0 peroxyneodecanoic acid, .alpha ., .alpha : x 267484 7

dimeth Ibenz I ester 2676145 26761-45-5 2,3-e o ro Ineodecanoate x x x 2686437-9 but Kin tris 2-eth Ihex Imerca toacetate US 2686437 26896-18-4 isononanoic acid x x x 2689618 26896-20-8 neodecanoic acid x x x 26896208 26998-97-0 calcium thiobis dodec I henolate x x x UK 2699897 27107-89-7 mono-n-octyRin tris (2-ethylhexylmercaptoacetate) x us 2710789

27176-87-0 dodec Ibenzenesul honic acid x x x x x 2717687
27178-16-1 diisode I adi ate x x x 27178161

27215-95-8 nonene x x x x us 2721595 27247-96-7 2-eth Ihe InRrate x x x 2724796 27458-92-0 tridecanol x 2745892 27458-94 2 isonon I alcohol x 2745894 2755426-3 diisooctyl phthalate x x x 2755426

27636-75-5 benzenesulfonic acid, c11 undecyl, sodium salt US 2763675
27813-02-1 methacrylic acid, monoester with propane-1,2-diol x x x 27813021

28348-53-0 sodium cumenesulphonate x x x 2834853

28473-21-4 nonanol x x x 2847321 29329-71-3 phosphonic acid, (1-hydroxyethylidene)di-, sodium x x x UK 2932971

saR x x x 2976121 29761-21-5 isode I di hen I phosphate 29911-28-2 1- 2-butox -1-meth lethox ro an-2-ol x x x US 29911282 29964-84-9 isodecyl metha late x x x US 2996484

30113-45-2 1- ro anamine, 3 isode lox - x x 3011345 30399-849 isooctadecanoic acid x x x 3039984 30618-849 acetic acid, mercapto-monoester with glycerol x us 3061884
31566-31 -1 Octadecanoic acid, monester with 1,2,3- x x 31566311

ro anetrio l 31570-04-4 tris 2,4-ditert-but I hen I phosphite x x x UK 31570044 32072-96-1 hexadecen Isuccinic anhydride x x x 32072961 32073-22-6 benzene, (1-methylethyl)-monosulfo deriv ., x 3207322

sodium sal t 32210-23-4 4tert-but Ic clohe I acetate x 32210234 32360-05-7 metha lic acid, octade I ester x x US 3236005 32588-76-4 N,N'-et hylenebis(3,4,5,6-tetrabromophthalimide) x x 32588764

33703-08-1 diisonon I adi ate x x x 33703081
34590-948 2-metho meth letho ro anol 12 x x x us 3459094 8

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 14 of 20

# P

. 19

ICCA HPV WORKING LIST August 200 3

CAS # Chemical Name assessed at EU
:iS9

:_ JP CAN SIDS Sponsor sort SIAM [see also http :!/cs3- [' written hq .oecd .org/scripts/hpv/ procedure] for the most recent picture l 34690-00-1 phosphonic acid,[[(phosphonnpmethyl) imini] bis x 34690001

[6,1-hexanediylnftrilobis(methene)]] tetrakis-,
3629004 36290-04-7 2-Naphthalenesulfonic acid, polymer with

formaldehyd e de, sodium sat 36653-82-4 hexadecan-l-ol x x x UK 3665382 36878-20-3 bis non I hen I amine x x 3687820 37475 88-0 benzenesulfonic acid, (1-methylethyl)-, ammonium x 3747588

sak 38051-10-4 2,2-bis(chloromethyl)trimethylene bis(bis(2- x x x (IRL+UK) :eu 38051104

chloroeth I hos 3864062 38640-62-9 bis iso roI na hthalene x x 40292-82-8 neodecano I chloride us 4029882 40372-72-3 4,4,15,15-tetraethoxy-3,16-dioxa-8,9,10,11- x x 4037272

tetrathia-4,15-disilaoctadecan e 42272-70-8 4- entadec lindene-3-tetradec loxetan-2-one UK 42272708 42978-66-5 (1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1- x x x US 4297866

ethanedi I dia 449y201 44992-01-0 [2-(acryloyloxy)ethyl]trimethylammonium chloride x x x x

45294-18-6 metha lic acid, eicos I ester x x US 452941 B 50849-47-3 5-non Isali laldeh de oxime x x 5084947 51000-52-3 vin I neodecanoate x x 5100052 52829-07-9 decanedioic acid, bis(2,2,6,6-tetramethyl-4- x x 5282907

i art in I este r 54849-38-6 meth Kin tris iso-oct Imerca toacetate x US 5484938 55680-03-0 4-unde lidine-3-dec loxetan-2-one UK 5568003 56000-16-9 (Z,Z)-4(heptadec-8-enylidene)-3-(hexadeo-7- 5600016

en I oxetan-2-on e 57583-34-3 meth Kin tris 2-eth Ihex Imerca toacetate x x US 5758334 57583-35-4 dimeth Kin bis 2-eth Ihex Imerca toacetate x x US 575833 57675-44-2 2-ethyl-2-[[(1-oxooleyl)oxy]methyl]-1,3-propanediyl x x x 5767544

dioleate 61260-55-7 N,N'-bis(2,2,6,6-tetramethylpiperidin-4-yl)hexane- x x 6126055

1,6-diamin 6178832 x x x 61788-32-7 te hen I, hydrogenated 61788-44-1 henol, st enated x x 61788441 61788-452 amines, h droenated tallow elk I x x x DE :eu 6178845
61788-46-3 amines, coco alkyl x x x DE :eu 617884 6 x x x 6178847 61788-47-4 fa acids coca 61788-63-4 amines, bis h dr enated tallow alk I meth I x x x 617886 61788-66-7 Fa acids, ve etable oil x x 6178866 6178876
61788-95-2 amines, (hydrogenated tallow elk I dimeth I x x x 61788952 61788-76-9 alkanes, chloro

x x !1III7S9O91 61789-01-3 fatty acids, tall oil, epoxidized, 2-ethylhexyl series x x 6178901

61789-09-1 I ceridea, tallow mono- , h dro enated x 61789-30-8 Felt acids, coco, tassium salts x x 6178930 8
61789-31-9 Fa acids, coco, sodium salts x x 6178931 61789-40-0 1-propanaminium, 3-amino-N-(rarboxymethyl)- x x x x 61789400

N,N-dimeth I-, N61789-45-5 6178945



### fatt acids, dehydrated castor-oil x x x 61789-53-5 nitrites, coco x x x 6178953 61789-71-7 quaternary ammonium compounds, benzylcoco x x 6178971

alk Idimeth I, ch i 617-79-5 amines, bis h dro enated tallow alkyl) x x 6178979

617 :9 9_86-4 sulfonic acids, petroleum, calcium sells x x x 61789864

61789-97-7 tallow x x x 6178997 61790-12-3 fatty tall-oil x x x 6179012 61790-18-9 amines, soya alkyl x x 6179018

61790-28-1 nitriles, tallow x x x 61790281 61790-29-2 nitrites, tallow, hydrogenated x x x 6179029
61790-33-8 amines, tallow alkyl x x x DE :eu 61790338
61790-37-2 Fatt acids, tallow x x 61790372 61790-38-3 fatt acids, tallow, hydrogenated x x 6179038
61790-42-9 amines, tris h dro enated tallow alk I x 6179042 61790-51-0 resin acids and ro sin acids, sodium salts x x x 6179051 61790-69-0 fatty acids, tall-oil, reaction with x x 61790 6

dieth lenetriamine 617y07y2 61790-79-2 Fatty acids, palm oil, sodium salts x 61791-31-9 ethanol, 2,2'-iminobis-, N-coco alkyl derivs . x x x 6179131
61791-444 ethanol, 2,2'-iminobis-, N-tallow alkyl derivs . x x 61791 61791-55-7 amines, Wallow alk Itrimeth lenedi- x x x 6179155
63393-82-8 alcohols, C12-15 X UK -- 63449-39-8 araffin waxes and h drocarbon waxes, chloro x x x x UK 63449398 64365-17-9 resin acids and rosin acids, hydrogenated, esters x x 643651 7

with nta 6474163 64741-63-5 na htha, etroleum , light catalytic reformed x x x U S
64741-65-7 na htha, etroleum , heav alk late x x US 6474165 64741-73-7 distillates, (petroleum), alkylate x x US 6474173

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 15 of 20

# p . 20

ICCA HPV WORKING LIST August 200 3
CAS p Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also h ttp:/lcs3- [' written hq .oacd .org/scripts/hpvl procedu re

] for the most recent Icturet 64741-84-0 na htha, troleum , solvent-refined li ht x x x US 6474184 64741-85-1 raffmates, (petroleum), sorption process x x US 64741851 64741-91-9 distillated, (petroleum), solvent-refi ned middle x x x US 647419191 64742-06-9 extracts, (petroleum), middle distillate solvent x x x US 6474206 64742-13-8 distillates et ro leum , acid-treated middle x 64742138 64742-46-7 distillates, (petroleum), hydrotreated middle x x x US 6474246 64742-47-8 distillates, (petoleum , h drotreated light x x x US 64742478 64742-48-9 naphtha, (petroleum), hydrotreated hea x x x US 6474248 64742-49-0 na ha, (petroleum), h drotreated li ht x x x US 64742490 64742-80-9 distillates, ( petroleum), hydrodesulfurized middle x x x 6474280
64742-81-0 kerosine, (petroleum), h drodesulfurized x x x US 6474281 64742-82-1 na tha, (petroleum), h drodesulfurized heav x x x US 64742821 64742-88-7 solvent naphtha, (petroleum), medium ali h . x x x US 6474288 64742-89-8 solvent naphtha, (petroleum , ti ht ali h . x x x US 64742898 64742-94-5 solvent naphtha, ro leum , hea arom . x x US 6474294 64742-95-6 solvent na htha, etroleum , li ht arom . x x x US 6474295 64771-72-8 araffins, (petroleum), normal C5-20 x x x US 64771728 65381-09-1decanoic acid, ester with 1,2,3-propanetri ol x x x 65381091

octanoate 65996-77-2 coke coal x x x 65996772 65996-78-3 light oil (coal), coke-oven x x x 6599678 65996-79-4 solvent naphtha coal x x x 6 5996794 65996-81-8 fuel gases, coke-oven x x x 65996818 65996-83-0 extracts, coal tar oil elk

. x x x 659968301 65996-87-4 extract residues (coal), tar oil elk

. x x x 659968741 65996-89-6 tar, coal, high-temp

. x x x 65996896 65996-96-5 terpenes and terpenoids, turpentine-oil, alpha- x x x 6599696

pinene fracti 65997-03-7 fatty acids, tall-oil, low-boiling x x x 6599703 65997-04-8 rosin, fumarated x x x 65997048 65997-06-0 rosin, hydrogenated x x x 6599706 65997-13-9 resin acids and rosin acids, hydrogenated, esters x x x 6599713

with glyce 66071-941 com, steep liquor x x x 66071941 66455-17-2 alcohols, C9-11 x x x UK 6645517 67701-02-4 fatt acids, C1418 x x x 6770102 67701-03-5 Fatty acids, C16-18 x x 6770103 67701-06-8 Faititir acids, C14-18 and C16-18, unsatd . x x 67701068 67701-07-9 Fatt acids, C16 and C18, unsatd . x x 6770107 67701-08-0 Fatt acids, C14 18 and C18, unsatd . x x 6770108 67701-09-1 Fatt y acids, C8-18 and C18, unsatd ., potassium x x 67701091

salt s 67701-10-4 Fatty acids, C8-18 and C18, unsatd ., sodium salts x x 67701104

67701-11-5 Fatty acids, C14-18 and C16-18, unsaid ., sodium x x 6770111

salts 67701-27-3 Glycerides, C14-18 x x 6770127 67701-28-4 Glycerides, C8-18 and C18-unsatd . Source oil : x x 6770128

Coconut oil, Palm kernel oi l 67701-29-5 Glycerides, C14-18 and C16-18-unsatd

. ( Source x x 6770129

oil : Tallow 67701-30-8 Glycerides, C16-18 and C18-unsatd

. (Source oil : x x 67701308

Soybean oil, Palm oil, Canola oil) 67701-32-0 Glycerides, C14-18 and C16-18-unsatd . mono- x x 6770132

and di67701-33-1 Glycerid es
, C14-18 mono- and di- x x 67701331 67762-25-8 alcohols, C12-18 x x x UK 6776225 67762-27-0 alcohols, C16-18 x x x UK 6776227 67762-30-5 alcohols, C14-18 x x x UK 6776230 67762-36-1 fractionated fa tty acids blends, C6-C12(incl . C6- x x 67762361

C1 0 67762-37-2 fa acids, C8-18 and C18-unsatd ., Me esters x x 67762372 67762-38-3 fatty acids, C16-18 and C18-unsatd ., Me esters x x x 6776238
67762-39-4 fatty acids, C6-12, Me esters x x x 67762394 67762-41-8 alcohols, C10-16 x x x UK 67762418 67762-44-1 Fatt acids, C6-12, sodium salts x x 67762441 67845-94-7 (, Z,Z)-4-(heptadeo8-enylidene)-3-(hexadec-7- UK 6784594

en I oxetan-2-one 67845-95-8 3-hexadec I-4- entadec Ideneeoxetan-2-one UK 67845958 67846-68-8 dimethylbis[2-[(1- x x 67846688

oxooctadec I ox eth I ammonium chlorid e 67859-51-2 zincate(2-), [[N,N'-1,2-ethanediylbis[N- x US 67859512

(carboxymethyl)glycinato))(4-)-N, N', O,O', ON, ON']- ,diammonium, OC-6-21 67905-26-4 1-triacontanol, aluminum salt x 679052 67905-27-5 1-octacosanol, aluminum salt x x 1 6790527 67905-28-6 1-hexacosanol, aluminum salt x x 6790528 67905-29-7 7 1-tetracosanol, aluminum salt x x 679052 9

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 16 of 20

# p . 21

ICCA HPV WORKING LIST August 200 3

CAS # Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also http :/fcs3- [' written hq .oecd .org/scripts/hpv/ procedure] for the most recent Ictu re l 67905-30-0 1-docosanol, aluminum salt x x 67905300 67905-31-1 1-eicosanol, aluminum salt x x 67905311 67905-32-2 1-tetradecanol, aluminum salt x x 67905322 67953-76-8 phosponic aid, (1-hydroxyethylidene)bis-, x x UK 67953768

potassium sel l 67989-23-5 1,2,4-benzenetricarboxylic acid, decyl octyl ester x x x 6798923
68002-64-2 nitriles, C16 and C18-unsatd . x x x 68002642 68002-79-9 fatty acids, C14-18 and C16-18 unsatd ., triesters x x 6800279

with trim e 68002-80-2 Fatty acids, C14-18 and C16-18 unsatd ., x 68002802

potassium salt s 68002-87-9 Fa tt acids, C14-18 and C16-22, unsaid

. x 6800287 68002-90-4 Fa tt acids, C10-16 x x 6800290 68081-81-2 benenesulfonic acid, mono-Cl0-16-alkyl derivs ., x x x US 6808181

sodium salts 68081-96-9 sulfuric acid, mono-CID-16-alkyl esters, x x x 6808196

ammonium salts 68081-98-1 sulfuric acid, mono-C14-18-alkyl esters, sodium x x 68081981

salts 68082-64-4 Fatty acids, vegetable oil, sodium sells x x 68082644 68130-43-8 sulfuric acid, mono-C8-18-alkyl esters, sodium x x 68130438

salts 68131-74-8 ashes (residues) x x x 68131748 68140-00-1 amides, coco, N- h drax eth I x x x 68140001 68153-01-5 Na hthalenesulfonic acids 6815301 68153-30-0 quaternary ammonium compunds, x x US 68153300

benzylbis(hydrogenated tallow alkyl)methyl, salt s with bentonit e 68186-90-3 Cl

.

. Pigment Brown 24 15 x JP 6818690 68187-59-7 coal, anthracite, calcined x x x 6818759 68201-59-2 resin acids and rosin acids, fumarated, sodium x x x 68201592

salt 68308-53-2 Fatty acids, soya x x 6830853 68333-80-2 alcohols, C14-16 x x x UK 68333802 68333-89-1 distillation residue from phenol (aromatic x 68333891

hydrocarbons, poly-cumene-phenol and residues )

68334-03-2 Fatty acids, C12-20 and C12-20, unsaid

. x x 68334032 68390-56-7 fatty acids, tallow, hydrogenated, dinners, diketene x x UK 6839056

derivatives 68391-11-7 pyridine, alkyl derivatives x x 6839111 68410-96-8 distillates, pet ., hydrotreated middle, inter .boiling x x x US 68410968
68410-97-9 distillates, (pet .), light dist. hydrotrt . process, low- x x x US 6841097

boil

. 68411-30-3 benzenesulfonic acid, C10-13-alkyl derivatives, x US 6841130

sodium salts 68412-37-3 silicic acid (H4SiO4), tetraethyl ester, hydrolyzed x x 6841237

68424-31-7 fatty C5-10, esters with pentaerythritol x x x 6842431 68424-37-3 Fa tt acids, C14-22 x x 684243731 68424-38-4 fatty acids, C16-18, sodium safts x x 6842438 68424-60-2 Glycerides, C16-22 and C18-unsatd . x 68424602 68425-17-2 syrups, com, hydrogenated x x x 68425172 68439-57-6 sulfonic acids, C14-16-alkane hydroxy and C14- x x x 6843957

16-alkene, sod 68439-70-3 amines, C12-16-alk Idimeth I x x 6843970 68440-15-3 fatty acids, palm-oil x x 6844015 68442-68-2 benzenamine, N- hen I-, styrenated x x 6844268 68457-79-4 phosphorodithioic acid, mixed 0,0-bis(iso-bu and x x x 6845779

ent I esters, zinc sells 68476-50-6 hydrocarbons, C . tore .5, C5-6-rich x x x US 68476506 68477-31-6 distillates, (pet .), cat.reformerfract . residue, low- x x US 6847731

boil

. 68511-50-2 11-propene, 2-meth I-, sulfu ri zed x x x 68511502 68512-02-7 benzene, tetra ro en I de rivs . x x x 6851202 68512-63-0 benzene, ethenyl-, distn . residues x x x 6851263 68515-25-3 benzene, C11-9-alkyl derivs

. x x x 6851525 68515-32-2 benzene, mono-Cl2-14-alkyl derivs ., fractionation x x 68515322

bottoms 68515-34-4 benzene, mono-C12-14-alkyl derivs ., fractionation x 68515344

bottoms, hea end s 68515-40-2 1,2-benzenedicarboxylic acid, benzyl C7-9- x x x 68515402

branched and line a 68515-41-3 1,2-benzenedicarboxylic acid, di-C7-9-branched x x FR 6851541

and linear al 68515-43-5 1,2-benzenedicarboxylic acid, di-C9-1 1 -branched x x x FR 6851543

and linear a

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .xls Page 17 of 20

# p . 22

ICCA HPV WORKING LIST August 200 3

CAS # Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also h ttp :l/cs3- (' written hq .oecd .org/scrlpts/hpv/ procedure] for the most recent Ictu re l 68515-47-9 1,2-benzenedicarboxylic acid, di-C11-14- x x x FR 6851547

branched alkyl ester 685156 68515-60-6 1,2,4-benzenetricarboxylic acid, tri-C7--branched x x

and linea 6851575 68515-75-3 hexanedioic acid, di-C7-9-branched and linear x x

elk I esters UK 6851593 68515-93-5 henol, nonyl derivs ., sulfides x x x 68516-18-7 decene, h droform lation products x x x UK 6851618 68526-84-1 alcohols, C8-10-iso- . C9-rich x x z 68526841 68526-86-3 alcohols, C11-14-is o- , C13-rich x x x 6852686 68526-89-6 octene, h droform lation roducts, hi h-boilin x x x 685268 68526-90-9 nonene, h droform lation roducts, hi h-boilin x x x 6852690 6852693-2 nonene, h droform lation products, low-boilin x x x 6852693 68526-96-5 he tene, h droform lation products, low-boilin z x x 6852696 68527-02-6 alkenes, C12-24, chloro x x x 6852702 68527-05-9 iso-non lacohol x x UK 6852705 68551-07-5 alcohols, C8-18 x x x 685510 7
8551-16-6 alkanes, C9-11-iso- x x us 685511
68551-17-7 alkanes, C10-13-is o- x x us 6855117
68551-19-9 alkanes, C12-14-is ox x x US 6855119
68551-20-2 alkanes, C13-16-iso- x x us 6855120 2 68556252 68556-25-2 1,9-octadecadien-l-one, Z-, dimer gg5g422 68584-22-5 benzenesulfonic acid, C10-16-a1k I derivs . x x 68585-47-7 sulfuric acid, mono-C10-16-alkyl esters, sodium x x x 68 547

salts 68603-15-6 alcohols, C6-12 x x x UK 6860315 68603-17-8 alcohols, C16-18, distillation residues x x UK 68603178 68603-42-9 amides, coco, N .N-bis(hvdrox-e#h-'% x x x x 6860342 68608-15-1 sulfonic acids, alkane, sodium salts x x 68608151 68608-26-4 suHonic acids, etroleum, sodium salts x x x 686082 68608-88-8 benzenesulfonic acid, mono-Cl1-13-branched x x x 6860888 8

elk I derivs . 68609687 68609-68-7 1-hexanol, 2-ethyl-, manuf . of, by-products from, x x x

distn . res 6860992 68609•92-7 9-octadecanoic acid (Z)-, epoxidized, ester with x

ro lene I cal 6861051 68610-51-5 phenol, 4-methyl-, reaction products with x x x

di clo entadiene 6861144 68611-44-9 silane, dichlorodimethyl-, reaction products with x x x

silica 68648248 68648-24-8 fatt acids, vegetable-oil, unsaid

. x x 

### 68649-42-3 phosphorodithioic acid, 0,0-di-C1-14alkyl esters, x x x 6864942

zinc it 6878396 68783-96-0 sulfonic acids, petroleum, calcium salts, x x x

overbased UK 6878426 68784-26-9 phenol, dodecyl-, sulfurized, carbonates, calcium x x x

salts, ove 6878434 68784-34-9 phosphorodithioic acid, mixed O,O-bis(hexyl and x x

iso-bu esters, zinc salts UK ggg1567g 68815-67-8 ihiobis tetra ro lene henol x x x 68855-24-3 benzene, C14-30-alk I derivs . x x 6885524
68855-45-8 henol, dodec I-, sulfurized, calcium salts x x x UK 6885545 68855-56-1 alcohols, C12-16 X UK 68855561 68909-18-2 pyridinium, 1-(phenylmethyl)-, Et Me derivs ., x x us 689091 8

chlorides 689100 68910-05-4 Reaction Byproducts of Ammonia and 2- x x

Aminoethanol 68911-61-5 alcohols, C18-32 x x UK 6891161 68936-98-1 benzene, 1-meth leth I-, distn . residues x x 6893698 68937-41-7 henol,iso ro lated, phosphate 3 :1 x x x 6893741
68937-64-4 alcohols, C2-20, aluminum salts x x 68937644
68937-75-7 Fait acids, C8-10 x x 6893775 68937-83-7 fa acids, C6-10, Me esters x x 6893783 68937-84-8 fatt acids, C12-18, Me esters x x x 68937848 68937-85-9 Fatt acids, coco, heavy fractions x x 6893785 68937-96-2 1 sulfides, di-tert-bu x x 6893796 68938-00-1 terpenes and terpenoids, turpentine-oil residues x x x 68938001

68938-03-4 octene, h droform lation roducts, low-boiling x 68938034
68938-07-8 fatt acids, C9-13-neo- x x 6893807 8 x 66938158 68938-15-8 fatt acids, coco, hydrogenate d 68953-58-2 quaternary ammonium compounds, x x US 68953582

bis h dr------ I tallow 0- 1 68955191 68955-19-1 sulfuric acid, mono-Cl2-18-alkyl esters, sodium x x

salts, 689552 68955-20-4 sulfuric acid, mono-Cl6-18-alkyl esters, sodium x

salts 6895537 68955-37-3 acid chlorides, tallow, h dro enated x z 68955-55-5 C12-18 Alk lidimeth laminoxide 6895555

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 18 of 20

# p . 23

ICCA HPV WORKING LIST August 200 3

CAS # Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor Sort SIAM [see also htt p://csS- ( ' written hq .oscd .org/scripts/hpv/ procedure] for the most recent Ietu re 68955-98-6 fa tty acids, C16-18 and C18-unsatd ., branched x x x 6895598

and linea r 68988-22-711,44 nzenedicarboxylic acid, dimethyl ester, x x x 6898822

man f

. of, b - 69011-06-9 hthalato 2- dioxotrilead x x x _ 6901106
69669-44-9 benzenesulfonic acid, C10-14 alkyl derivs ., ~

sodium salt 7002467-8 benzenesulfonic acid, C16-24alk I derivs

. x x x 7002467

70024-92-9 alkanes, C7-8-isox x US 7002492

7008485-4 Fa Acids, tallow, distn . Residues x x 70084854

70248-27-0 Fatty animal, distn . Residues x x 7024827

70321-72-1 fatty acids, C8-18 and C18-unsatd ., distn . x x x 70321721

residues 70321-73-2 Fatt y acids, C14-18 and C16-18-unsatd ., distn . x x 7032173

residues 70356-32-0 benzene, C1426-alk I derivs
. X x x 7035632

592-80-2 amines, C10-16-alk Idimeth I, N-oxides x x x 7059280 70 70693-06-0 a ro matic hydrocarbons, C9-11 x x US 7069306
70955-11-2 hexene, h d rofomt lation roducts x x x UK 7095511 71011-26-2 Quaternary ammonium compounds, x x 71011262

benzyl(hydrogenated tallow alkyl)dimethyl, salts with hectorite 71011-27-3 quaternary ammonium compounds, x x x 7101127

bis h d ro enated tallow alkyl 71888-89-6 1,2-benzenedicarboxylic acid, di-C6-8-branched x x x 71888896

alkyl esters , 72275-86-6 alkenes, C15-18 alpha, reaction products with x UK 722758615

sulfurized tetrapropenyl phenol, calcium salt , sulfurized 72379-28-3 fatty acids, tallow, hydrogenated, distn . residues x x 7237928

72480-57-0 Fatty acids, tallow, hydrogenated, stearic acid x 7248057

fraction distn . residue s 73398-61-5 glycerides, mixed decanoyl and octanoyl x x 7339861

73758-62-0 phenol, C12-and C18-30-alkyl derivs ., sulfurized, x x UK 7375862

calcium s a 74499-35-7 Phenol, etra ro en I Derivs x x UK 7449935

75782-86-4 alcohols, C12-13 x x x UK 75782864

75782-87-5 alcohols, C14-15 x x UK 7578287

80206-82-2 alcohols, C12-14 x UK 80206822 84605-29-8 phosphorodithioic acid, mixed O,O-bis(1,3- x x x 8460529

dimeth Ibut I an d 84961-70-6 benzene, mono-C10-13-alkyl de rivs ., distn . x x x 849617

residue s 84989-41-3 2-oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene x x UK 8498941

derivs

. 85117-41-5 benzene, mono-ClO-14 derivs ., fractionation x x 8511741

bottom s 85117-50-6 benzenesulfonic acid, mono-cl0-14, monoalkyl, x US 85117506

sodium sal

t 85422-92-0 araffin oils, chloro- x UK 8542292 85507-79-5 diundec I hthalate, branched and linear x x FR 85507791
86089-17-0 tride lamine, branched and linear DE 8608917 88917-22-0 ro anol, 2-methox meth ethox D GMEA x US 8891722
90194-45-9 benzenesulfonic acid, mono-c10-13, alkyl, sodium x 9019445

sel l 90268-59-0 poly-basic lead fumerate 902685 90387-57-8 formaldehyde, reaction products with sulfonated 14/15 x DE 90387578

1,1'-oxybis[methylbenzene],sodium salts
90622-46-1 alkanes, C1416 x x x us 90622461
90622-56-3 alkanes, C7-10-is o- x us 9062256

90622-57-4 alkanes, C9-13 x US 9062257 90622-58-5 alkanes, C11-15, is ox US 9062258
90640-86-1 distillates (coal tar, heavy oils x x x 90640861

91078-68-1 Naphthalenesulfonic acids, reaction products with x 91078681

formaldehyde, sodium salts 92045-53-9 naphtha (petroleum), hydrodesulf . light, dearoma
. x US 9204553

92062-15-2 solvent naphtha (pet .), hydrotrt

. light naphthenic x US 9206215

92112-69-1 hexane, branched and linear x US 92112691

9392407-3 alkanes, C10-14 x i x US 9392407
9392463-1 Naphthalensulfonic acids, reaction products with x 93924631

formaldehyde, ammonium salts 94094-93-6 benzene, mono-Cl 0-1 3-alkyl de rivs ., fractionation x x YA936

bo ttoms, heavy ends 9410914 94109-14-5 2-he tad lidene-4-hexadec loxetan-3-an e 98246-87-8 2-oxetanone, 3-C1416-alkyl-4C15-17-alkylidene UK 98246878

derivative s

Prepa red by ICCA 27 August 2003 File ICCA Working List - August 2003 .x1s Page 19 of 20

# p . 24

ICCA HPV WORKING LIST August 2003

CAS Al Chemical Name assessed at EU US90 US94 JP CAN SIDS Sponsor sort SIAM [see also h ttp:llcs3- [' writt en hq .oecd .org/acripts/hpvl procedure] for the most recent 

### icturel 102242-51-3 fatly acids, c6-C24 satd and C6-24 unsatd, distn

. x 10224251

residue s 117875-77-1 sulfuric acid, mono-Cl0-16-alkyl esters, compds

. x x 117875771

with triethanolamine

7x121250-47-3 Fatty acids, c6-C24 said and C6-24 unsaid, distn

. x 12125047

Residue s 121158-58-5 Dode I henol, mixed isomers branched UK 121158588 122384-85-4 phenol, tetrapropenyl-, suBurized, calcium salts x UK -122384854

122384-87-6 phenol, tetrapropenyl-, sulfurized, carbonates, x UK 12238487

calcium salts, overbased 129813-62-3 benzene, mono-C10-C13 alkyl derivs ., x x 12981362

fractionation bottoms, li ht end s 129813-67-8 alkanes, C12-14 x x US 129813678 151911-58-9 benzene, mono C12-C13 branched alkyl derivs ., x 15191158

fractionation bottom 201687-57-2 fatt y acids, tall oil, 2-mercaptoethylesters, reaction US 201687572

products with dlchiorodimethyistannane, sodiu m sulfide and trichloromethylstannan e
210555-94-5I, 4-dode I branched UK 21005594

Prepared by ICCA 27 August 2003 File ICCA Working List - August 2003.xls Page 20 of 20