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### UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

**WASHINGTON, D.C. 20460**

**OFFICE OF CHEMICAL SAFETY**  **AND POLLUTION PREVENTION**  

### MEMORANDUM
**Date: 7**  **/ 24**  **/201 2** 
**SUBJECT: Fenpropathrin**  Acute Aggregate Dietary (Food and Drinking Water) Exposure and Risk Assessment for the Section 3 Registration Action on the Tropical Fruits Guava, Acerola, Feijoa, Jaboticaba, Passionfruit, Starfruit, Wax Jambu, Lychee, Longan, Spanish L ime, Pulasan, Ramb utan, Sugar Apple, Atemoya, Biriba, Cherimoya, Custard Apple, I lama, and Soursop , and a Tolerance Without U.S. Registration on Tea

**PC Code:** 127901 **DP Barcode:** D 402246 **Decision No.:** 4 17627 **Registration No. :**  59639

- 35 **Petition:** 9 E 7 594 **Regulatory Action:**  Section 3 Registration **Risk Assessment Type:** Dietary **Case No.:** 7601 **T XR No.:**  NA **CAS No.:** 39515

- 41

- 8 **MRID No.:** NA **40 CFR:** § 180.466

**FROM:** Douglas Dotson, Ph.D., Chemist

Risk Assessment Branch II Health Effects Division (7509P)
**THROUGH:** Donna Davis , Chemist

Sheila Piper , Chem ist Dietary Exposure Science Advisory Council (DESAC)
**TO:** Laura Nollen/ Barbara Madden, RM Team 5

RIMUERB Registration Division (7505P)

**Executive Summary**
An a cute aggregate dietary (food and drinking water) exposure and risk assessment w as conducted using the Dietary Exposure Evaluation Model DEEM

- FCIDTM, Version 2.03 which use s foo d consumption data from the U.S. Department of Agriculture’s (USDA’s) Continuing

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

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### Survey s of Food Intakes by Individuals (CSFII) from 1994

- 1996 and 1998

. The anal ys es were conducted as part of a human health risk assessment for the requested uses of the py rethroid insecticide , fenpropathrin , o n the tropical f ruits gu ava, a cerola, f

eijoa, j aboticaba, p assionfruit, s tarfruit, w ax j ambu, l yc hee, l ongan, S panish l ime, p ulasan, r ambutan, s ugar a pple, atemoya, b iriba, c herimo ya, c ustard a pple, i lama, and s oursop
. Inaddition, the registrant proposed a t olerance w ithout U.S. r egistration on t ea . These uses are being requested by the Interregional Research Project Number 4 (IR

- 4). Tolerances have already been established for the tropical fruits avocado, canistel , mango, papaya, salal, sapodilla, black sapote, mamey sapote, and star apple. A chronic dietary

exposure assessment was not performed because a chronic dietary endpoint was not selected for fenpropathrin. A chronic dietary endpoint is not required beca use repeated exposure to fenpropathrin does not result in a point of departure lower than that resulting from acute exposure . Therefore, the acute dietary risk assessment is pro tective of chronic dietary risk

. An assessment for cancer was not performed because fenpropathrin was classified as “not likel y to be carcinogenic to humans

. ” As a result, an acute assessment was the only dietary exposure assessment performed for fenpropathrin. The acute dietary

endp oint selected for children is the same as that selected for adults

. D ecreased motor activity was observed in a motor activity study . The FQPA Safet y Factor was reduced to 1x for adults; however, it was only reduced to 3x for children six years of age or yo unger. As a result, the a c ute population adjusted dose (aPAD) for children (0.017 mg/kg/day) is lower than that for adults (0.05 mg/kg/day). Initially , an unrefined assessment based on tolerance level residues and 100% crop treated assumptions was perf ormed for fenpropathrin. There were no risks of concern for youth and adults; however, there were risks of concern for the population subgroups comprised of infants and children. As a result, the assessment was refined by incorporating distributions of f ield trial values, Pesticide Data Program (PDP) monitoring data, and estimates of percent crop treated. For most processed commodities, DEEM default processing factors were used for those commodities for which they were available

. In some cases, empirica l processing factors were use d

. For drinking water, a very conservative surface water estimated drinking water concentration (EDWC) generated with the FIRST Model was used. As a result of the fact that man y conservative assumptions were made for this ass essment, in particular, the use of field trial data (as opposed to monitoring data) for many commodities, HED is confident that the acute dietary exposure assessment s ignificantl y ov erestimate s risk to the general U.S. population and all population subgroup s
. The acute risk estimates are below HED’s level of concern for all population subgroups, including those comprised of infants and children. Generally , HED is concerned when risk estimates exceed 100% of the population

- adjusted dose (PAD). The acute risk estimate for the general U.S. population is 19 % of the aPAD. The population subgroup with the highest acute dietary risk estimate is Children 3

- 5 , which uses 9 7 % of the aPAD. As percent crop treated estimates were incorporated into the assessment, the risk estimates are being reported at the 9 9.9 th 

### percentile of exposure.

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### I. **Introduction** Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose (i.e., the dose which HED has concluded will result in no unreasonable adverse health effects). This dose i s referred to as the population

- adjusted dose (PAD). The PAD is equivalent to the point of d eparture (POD, NOAEL, LOAEL, e.g.) divided by the required uncertainty or safet y factors.
For acute and non

- cancer chronic exposures, HED is concerned when estimated dietary risk exceeds 100% of the PAD. References which discuss the acute and chronic ris k assessments in more detail are available on the EPA/pesticides web site: “Available Information on Assessing Exposure from Pesticides, A User’s Guide,” 21 Jun 2000, web link: http://www.epa.gov/fedrgstr/EPA

- PEST/2000/July /Day

- 12/6061.pdf

; or see SOP 99.6 (20 Aug 1999). The most recent dietary

exposure assessment performed for fenpropathrin was performed in 2008 (D356137, A. Parmar, 11 /26 /2008). Then in 2011, HED performed a s creening

- level cumulative risk assessment for the p yrethroids and pyrethrins as a class (D394576, 10/4/2011, K. Whitby ). This risk assessment included a dietary exposure anal ys is in which it was concluded that there were no dietary risks of concern for th e py rethroids and py

rethrins.
**II. Residue Information**  HED has determined that the residue of concern in plant and animal commodities for risk assessment is parent f

enpropathrin . Parent compound is also the residue of concern for risk assessment in drinking water. Proposed Commodities As stated above, the current tolerance petition includes the tropical f ruits gu ava, a cerola, f

eijoa, j aboticaba, p assionfruit, s tarfruit, w ax j ambu, l ych ee, l ongan, S panish l ime, p ulasan, r ambutan, s ugar a pple, atemoya, b iriba, c herimo ya, c ustard apple, i lama, and s oursop . In addition, the registrant proposed a t olerance w ithout U.S. r egistration on t ea
. The recommended tolerances for the proposed commodities were used i n the assessment. The se tolerances are provided in Table 1, below.
Table 1. Fenpropathrin : Recommended Tolerances for Proposed Tropical Fruits and Tea Commodity Recommended Tolerance (ppm) Acerola, Feijoa, Guava, Jaboticaba, Passionfruit, Starfruit, Wax j ambu 3.0 Longan, Lychee, Pulasan, Rambutan, Spanish lime 7 .0 Atemoya, Biriba, Cherimoya, Custard apple, Ilama, Soursop, Sugar apple 1. 5 Tea 2.0

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### Registered Commodities For registered commodities, tolerances, distributions of field trial data, and distributions of monitoring data were used. The use of the various ty pes of data is discussed below. At times it was necessary

to translate data from certain commodities to other commodities. These data translations were performed according to the standard operating procedures (SOPs) that govern these translations. Field trial data were translated according to the guidance given in HED SOP 2000.1: Guidance for Translation of Field Trial Data from Representative Commodities in the Crop Group Regulation to Other Commodities in Each Crop Group/Subgroup. Monitoring data were translated according to the guidance given in HED SOP 99.3: Translation of Monitoring Data.
Residue Point Estimates: Tolerances Tolerances for fenpropathrin are established in 40CFR § 180.466. In the analy sis, tolerance level residues were used for commodities that did not contribute significantl y to the risk estimates (i.e., were not “risk dri vers”). Tolerance level residues were used for Chinese broccoli, kohlrabi, peas, eggplant, okra, peppers, tomatillo, blended tomato commodities, cantaloupe, casaba melon, honeydew melon, balsam pear, chayote fruit, Chinese waxgourd, pumpkin, citrus citron , citrus hy brids, citrus oil, lemons, limes, orange peel, pummel, crabapple, loquat, quince, boy senberry , dewberry , loganberry , currant, elderberry , gooseberry , avocado, canistel, cherimoya, cottonseed, grape leaves, dried mango, dried papaya, peanuts, mam ey sapote , and all tree nuts

. Tolerance level residues were also used for livestock commodities

. Inthe previous fenpropathrin risk assessment (D313330, D. Dotson, 11/26/2008), HED recommended in favor of reassessed tolerances for cattle, goat, hog, hors e, and sheep commodities. HED recommended that the tolerance for the meat and meat by products of cattle, goats, horses, and sheep be reduced to 0.01 ppm. HED recommended that the tolerance for the fat of these same commodities be reduced to 0.05 ppm. HE D recommended that tolerance for milk fat be reduced to 0.05 ppm (reflecting 0.002 ppm in whole milk). Finall y, HED recommended that the tolerances for hog commodities (fat, meat, and meat b yproducts) be removed. The revisions have not been made to the 4 0CFR listing for fenpropathrin ; however, HED reiterate s the need for these changes and has included those reduced levels in this risk assess ment.
Residue Data Dis tributions
R esidue distribution files (RDFs) were generated for the risk drivers . These RDFs were comprised of either field trial values or P DP monitoring values. Monitoring data were used when they

were available. When they were not available, field trial values were used.
Field Trial Data
Distributions of field trial values were used for Brussels sprouts, cabbage, Chinese napa cabbage, tomatoes, cucumbers, grapefruit, apricots, cherries, nectarines, peaches, plums, blackberries, raspberries, mango, olive, and papaya. As stated above, field trial data were translated accordin g to the guidance given in HED SOP 2000.1. Cabbage field trial data were translated to Brussels

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### sprouts and Chinese napa cabbage. Peach field trial data were translated to apricots and nectarines. Finall y, avocado field trial data were translated to man go and papaya and guava field trial data were translated to passionfruit

. Tropical fruits are not listed in SOP 2000.1. However, these fruits are all tropical fruits with inedible peel, and HED believes that these translations are appropriate

. PDP Data Distributions of monitoring data values were used for broccoli, Chinese mustard cabbage, cauliflower, watermelon, squash, oranges, tangerines, apples, apple juice, pears, blueberries, huckleberries, grapes, grape juice, and strawberries. Monitoring data from the years 2007 through 2010, inclusive, were used. As stated above, monitoring data were translated according to the guidance given in HED SOP 99.3. Broccoli PDP data were translated to Chinese mustard cabbage and cauliflower. Orange PDP data were translated to tangerines. Finally , blueberry PDP data were translated to huckleberries. Bushberries are not listed in SOP 99.3. However, as blueberries and huckleberries are similar crops and are both in Crop Subgroup 13

- 07B (Bushberry

subgroup), bluebe rry

data were translated to huckleberries.
Residue Data for Blended Commodities The acute residue input file includes the following blended commodities: dried bell pepper, dried nonbell pepper, tomato paste, tomato puree, dried tomatoes, pumpkin seed, d ried tea, instant tea, peanuts, peanut butter, peanut oil, citrus oil, almond oil, filbert oil, cottonseed oil, olive oil, dried apple, dried pear, dried apricot, dried peach, and dried papaya. For all of these commodities, a point estimate was used as th e residue value. In most cases, the point estimate was the tolerance. The average field trial value was used for dried apples, dried pears, and dried peaches. The average peach field trial value was translated to dried apricots. For these blended commo dities, the percent crop treated estimates were entered directl y into the Adjustment Factor 2 column. Percent crop treated estimates were used for tomato paste, tomato puree, dried tomatoes, dried apples, dried pears, dried apricots, dried peaches, cotton seed oil, and olive oil.
The residue data discussed above are summarized in Attachment 3

. Processing Factors The processing factors used in the anal ys is are provided in the previous dietary exposure assessment performed for fenpropathrin (D 356137, A. Parmar, 11/26/2008). These same factors are being used in the current assessment. The registrant performed processing studies on some of the commodities in the anal ys is. Empirical processing factors were used for citrus, grapes, melons, peanuts, apples, plums and tomatoes. When empirical processing factors were not available, default processing factors from DEEM (Version 7.81) were used. The DEEM default processing factors were used for dried apples, dried apricots, dried beef, dried papaya, dried peac hes, dried pear, peanut butter, cherry juice, papaya juice, and plum juice. Table 2 below lists the empirical processing factors and the DEEM 7.81 default processing factors that were used in the anal ys es.

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### Table 2: Processing Factors Used in Fenpropathrin Dietary Exposure Assessment **Commodity Process**  **Factor Reference**  Apple Dried 8.0 DEEM 7.81 Default Apricot Dried 6.0 DEEM 7.81 Default
Beef Dried 1.92 DEEM 7.81 Default Cantaloupe Peeled 0.02 D257376 Cherry Juice 1.5 DEEM 7.81 Default
Citrus Juice 0.06 D257376
Citrus Peel Peeling 2.6 D257376 Grapes Raisins 1.54 D257376 Grapes Wine 0.003 D257376 Melons (except Watermelon) Peeling 0.02 D257376

Papaya Dried 1.8 DEEM 7.81 Default Papaya Juice 1.5 DEEM 7.81 Default
Peach Dried 7.0 DEEM 7.81 Default
Peanuts Refined Oil 4.0 D257376
Peanuts Peanut Butter 1.89 DEEM 7.81 Default
Pear Dried 6.25 DEEM 7.81 Default
Plum Juice 1.4 DEEM 7.81 Default
Plum Prune (Dried) 2.6 D333113
Tomatoes Washing 0.83 D257376
Tomatoes Juice 0.05 D257376
Tomatoes Paste 0.3 D257376
Tomatoes

- Dried Washing x Drying 0.83 x 14.3 = 11.87 D257376 and DEEM 7.81



### Residue s in Fish Fenpropathrin has a low water solubility and a high octanol/water partition coefficient. As a result, it will not dissolve in water to an y significant extent. Residues have the potential to partition into sediment at the bottoms of water bodies, however. Catfish are bottom feeders and residues in catfish serve as a marker for pesticide residues. The USDA Pesticide Data Program

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### (PDP) monitored pesticide residues in catfish in 2008, 2009, and 2010. Over this 3

- ye ar period, PDP analy

zed 1,458 samples of c atfish for fenpropathrin residues. None of the samples contained detectable residues. As a result, residues in fish are not an important issue for fenpropathrin and were not included in the assessment.

**III**
**. Percent Crop Treated Information** 
The Biological and Economic Analy sis Division (BEAD) provided a Screening Level Usage Analy sis (SLUA) for fenpropathrin (D 402054 , S

. Haddad , 5 /25 /201 2 ). The SLUA provided maximum percent crop treated estimates for commodities with established tolerances. The percent crop treated estimates were used to prepare the RDFs for nonblended and partiall y blended commodities. For blended commodities, the percent crop treated estimates were entered directly in the Adjustment Factor #2 column in the DEEM input file. T he SLUA is included in this dietary

exposure memo in Attachment 5

. Not all of the percent crop treated estimates in the SLUA were used in the assessment. The values that were used are given in Table 3, below.

Table 3

. Maximum Percent Crop Treated Esti mates Used in Acute Dietary Exposure Assessment

Commodity Maximum

% Crop Treated Commodity Maximum % Crop Treated Apples 15 Grapes 10 Apricots 2.5 Nectarines 2.5 Blueberries 2.5 Oranges 35 Broccoli 2.5 Peaches 2.5 Brussels Sprouts 10 Pears 10 Cabbage 2.5 Plums/Prunes 2.5 Cauliflower 2.5 Squash 2.5 Cherries 5 Straw berries 50 Cotton 2.5 Tangerines 15 Cucumbers 2.5 Tomatoes 10 Grapefruit 35 Watermelon 2.5



### IV. **Drinking Water Data** The Environmental Fate and Effects Division (EFED) p rovided the results of a drinking water assessment that was performed for fenpropathrin ( D368174, Jose Melendez, 4/26/2010 ). In this memo, EFED stated that the results of a previous assessment (D 313331 , J. Melendez, 9/3/2008) should be used in the current dietary exposure analy sis

. Water numbers were based on parent only because the degradates occurred at low levels in the laboratory studies. The EFED memo of 9/03/2008 provided Tier 1 estimated environmental concentrations for fenpropathrin that were

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### cal culated using the FIRST Model for surface water and the SCIGROW Model for groundwater. For surface water, the acute (peak) water concentration is 10.3 ppb. The groundwater screening concentration is 0.005 ppb. These values generally represent upper

- boun d estimates of the concentrations that might be found in surface water and groundwater resulting from the use of fenpropathrin on grapes, because this is the scenario that results in the highest estimated drinking water concentrations (EDWCs). For the acute dietary exposure assessment, the peak water concentration value of 10.3 ppb was used. The model and its description are available at the EPA internet site: http://www.epa.gov/oppefed1/models/water /

.

**V. DEEM** 

**- FCIDTM Program and Consumption Information**  The fenpropathrin acute dietary exposure assessment w as conducted using the Dietary Exposure Evaluation Model software with the Food Commodity Intake Database DEEM

- FCIDTM,Version 2.03 which incorporates consumption data from USDA’s CSFII, 1994

- 1996 and 1998. The 1994

- 96, 98 data are based on the reported consumption of more than 20,000 individuals over two non

- consecutive survey day s. Foods “as consumed” (e.g., apple pie) are linked to EPA

defined food commodities (e.g. apples, peeled fruit

- cooked; fresh or N/S; baked; or wheat flour

- cooked; fresh or N/S, baked) using publicl y available recipe translation files developed jointly by USDA/ARS and EPA. For chronic exposure assessment, consumption data are averaged for the entire U.S. population and within population subgroups, but for acute exposure assessment are retained as individual consumption events. Based on anal ys is of the 1994

- 96, 98 CSFII consumption data, which took into account dietary patterns and survey respondents, HED concluded that it is most appropriate to report risk for the following popul ation subgroups: the general U.S. population, all infants (<1 ye ar old), children 1

- 2, children 3

- 5, children 6

- 12, youth 13

- 19, adults 20

- 49, females 13

- 49, and adults 50+ years old. For acute exposure assessments, individual one

- day food consumption dat a are used on an individual

- by

- individual basis. The reported consumption amounts of each food item can be multiplied by

a residue point estimate and summed to obtain a total daily pesticide exposure for a deterministic exposure assessment, or “matched” i n multiple random pairings with residue values and then summed in a probabilistic assessment. The resulting distribution of exposures is expressed as a percentage of the aPAD on both a user (i.e., onl y those who reported eating relevant commodities/food f orms) and a per

- capita (i.e., those who reported eating the relevant commodities as well as those who did not) basis. In accordance with HED policy, per capita exposure and risk are reported for all tiers of anal ysis. However, for tiers 1 and 2, an y sign ificant differences in user vs. per capita exposure and risk are specificall y identified and noted in the risk assessment.

**V I** 
**. Toxicological Information**  Adequate data have been submitted to characterize the toxicity o f fenpropathrin for the purposes o f dietary risk assessment. The acute dietary endpoint was based on decreased motor activity seen in a motor activity

study

. A chronic dietary endpoint is not required because repeated exposure to fenpropathrin does not result in a lower point of departure. Therefore, the acute

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### endpoint is protective of chronic exposure scenarios. The FQPA Safet y Factor was reduced to 1x for youth and adults; however, it was reduced to 3x for children 6 years of age and under. The additional safet y factor for children i s based on the increased quantitative susceptibility seen in the scientific literature related to p yr ethroid pharmacokinetics (D381210, E. Scollon and A. Lowit, 6/27/2011). In accordance with the EPA ’ s Final Guidelines for Carcinogen Risk Assessment (March, 2005), fenpropathrin was classified as “ not likely to be carcinogenic to humans. ” The fenpropathrin doses and endpoints for dietary exposure assessment are summarized in Table 4 , below

. **Table 4. Summary of Toxicological Doses and Endpoints for Fenpropathrin**  **Exposure Scenario**  **Dose Used in Risk**

**Assessment, UF FQPA SF and LOC for Risk**  **Assessment Study and Toxicological**  **Effects** Ac ute Dietary

- ( ≥ 6 years old) Wolansky BMDL 1S D =

5.0 mg/kg UF = 100 Ac ute RfD = 0.05 mg/kg FQPA SF = 1X aPAD = acute RfD FQPA SF = 0.05 mg/kg/day Wolansky BMD 1S D = 6.4 mg/kg based on decreased motor activity

Ac ute Dietary

- (< 6 years old) Wolansky BMDL 1S D =

5.0 mg/kg

UF = 100 Ac ute RfD = 0.05 mg/kg FQPA SF = 3X
aPAD = acute RfD FQPA SF = 0.017 mg/kg/day Wolansky BMD 1S D = 6.4 mg/kg based on decreased motor activity

Chronic Dietary A chronic dietary endpoint is not required because repeated exposure to fenpropathrin does not

result in a lower point of departure. Therefore, the acute endpoint is protective of chronic exposure scenarios. Cancer Classification: “not likely to be carcinogenic to humans” in accordance with the EPA Final

Guidance for Carcinogen Risk Assessment (3/29/05) BMDL=Bench Mark Dose Level, 1SD=One Standard Deviation, UF = uncertainty factor , RfD = reference dose , aPAD = acute population adjusted dose



### V **I I.**  **Results/Discussion** As stated above, for an acute d ietary exposure assessment, HED is concerned when dietary risk exceeds 100% of the aPAD. The DEEM

- FCIDTM anal ys es estimate the dietary exposure of the U.S. populat ion and various population subgroups. The results reported in Table 5 are for the general U.S. Population, all infants (<1 ye ar old), children 1

- 2, children 3

- 5, children 6

- 12, youth 13

- 19, females 13

- 49, adults 20

- 49, and adults 50+ years. Risk estimate s are below HED’s level of concern for the general U.S. population and all population subgroups. The acute risk estimate for the general U.S. population is 19 % of the aPAD. The population subgroup with the highest acute risk estimate is Children 3

- 5 , which uses 9 7 % of the aPAD. A f ull listing of the exposure and risk estimates is included in Attachment 2

. Residues in drinking water made a negligible contribution to the risk estimates.

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

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**.** Summary of the Acute Exposure and Risk Estimates for Fenpropathrin Population Subgroup Ac ute Assessment (9 9.9 th Percentile) Chronic Assessment

aPAD, mg/day Exposure Estimate,

mg/day %

aP AD c PAD,

mg/day Exposure Estimate,

mg/day % c P AD U.S. Population 0.05 0.0 09 489 19

NA NA NA All infants 0.017 0. 011 457 6 7 Children 1

- 2 y

rs 0.017 0. 0153 4 3 90 **Children 3**

**- 5 yrs**  ***** 0.017 **0. 016**  **4 88**  **9 7**  Children 6

- 12 y

rs 0.05 0.0 134 89 27 Youth 13

- 19 y

rs 0.05 0.0 09 290 1 9 Adults 20

- 49 y

rs 0.05 0.0 07 920 16 Adults 50+ yrs 0.05 0.0 080 93 16 Females 13

- 49 y

rs 0.05 0.0 084 76 17 *Most highly exposed population subgroup



### VI **I I.**  **Characterization of Inputs/Outputs**
HED considers the acute assessment to be partially refined, but at the same time, very health

protective

. Refinements were made to m ost of the risk drivers in the assessment; however, in many cases, these refinements consisted of the incorporation of field trial data. HED has learned from past experience that monitoring data are often sign ificantl y lower than field trial data. Monitoring data more accuratel y represent the residue levels to which people will actually be exposed to pesticide residues in their diets. In 2004, HED compared field trial and monitoring data for the p yr ethroids p ermethrin, lambda cy halothrin, and esfenvalerate. For those compounds, the monitoring data were one to two orders of magnitude lower than the field trial data for the same commodities. If monitoring data were available for more of the risk drivers, parti cularl y stone fruits, raspberries, and blackberries, the risk estimates would have been considerabl y lower. The assessment is also con servative in that tolerance level residues were used for man y commodities. Percent crop treated estimates ranged from co nservative to moderately refined. For many commodities, the assumption was made that 100% of the crop would be treated. For other commodities, maximum percent crop treated estimates were incorporated. These estimates are based on past usage data and are considered to be very reliable. Percent crop treated estimates were not available for two of the risk drivers for children 1

- 6 years of age, raspberries and blackberries. As a result, 100% crop treated was used for these commodities. If usage estimates were available and had been used, the risk estimates for the population subgroups, Children 1

- 2 and Children 3

- 5 , would have been lower.
P rocessing factors also ranged from conservative to refined. DEEM default factors were used for some commodities whe reas empirical processing factors were used for others. The risk estimates would be significantly lower if monitoring data were available for more of the risk drivers in the anal ys is. More monitoring data will be available in the future. The anal ys i s could be refined further by incorporating percent crop treated estimates for new uses. However,

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### as all risk estimates are not of concern, it is not necessary to make any further refinements to the dietary exposure assessment at this time

.

**I X** 
**. Conclusions**  The exposure estimates that were generat ed are refined estimates of the actual dietary exposures that m ight occur. T he acute aggregate (food + water) dietary risk estimates are below HED’s level of concern for the general U.S. population and all population subgroups. HED is confident that the assessment do es not underestimate risk to the general U.S. population or any population subgroup.

**X. List of Attachments** 
Attachment 1. A cute D ietary Residue Input File Attachment 2. Results of Acute Dietary Exposure Assessment Attachment 3

. Residue Inputs for Individual Commodities Attachment 4

. Residue Distribution Files Attachment 5. Screening L evel Usage Anal ys is

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### Attachment 1: Fenpropathrin Residue Input File Acute NOAEL: 5 mg/kg/day Acute PAD: 0.05 mg/kg/day for Adults , Youth , and Children Over 6 Years of Age Acute PAD: 0.017 mg/kg/day for Children 6 Years of Age and Under
DEEM

- FCID Version 2.03
Filename: C: \Documents and Settings \ ddotson\My Documents \DEEM FCID \Fenpropathrin\FenpropAcutePDP.R98
Date created/last modified: 0 6

- 10

- 2012/1 0 : 40 : 51 /8

-------------------------------------------------------------------------------- RDL indices and parameters for Monte Carlo Analysis: Index Dist Parameter #1 Param #2 Param #3 Comment # Code

----- ---- ------------ -------- -------- ------- 1 6 ApplePDP15pct.RDF 2 6 PearPDP10pct.RDF 3 6 GrapePDP10pct.RDF 4 6 CherryFT5pct.RDF 5 6 PeachFT2.5pct.RDF 6 6 Plu mFT2.5pct.RDF 7 6 BroccoliPDP2.5pct.RDF 8 6 OrangePDP35pct.RDF 9 6 BlueberryPDP2.5pct.RDF 10 6 StrawberryPDP50pct.RDF 11 6 GrapefruitFT35pct.RDF 12 6 CaneberryFT100pct.RDF 13 6 Apricot2.5pct.RDF 14 6 Cabba geFT2.5pct.RDF 15 6 PapayaFT100PctCT.RDF 16 6 TangerinePDP15Pct.RDF 17 6 WatermelonPDP2.5pct.RDF 18 6 OliveFT100PctCT.RDF 19 6 TomatoFT10pct.RDF 20 6 CucumberFT2.5PctCT.RDF 21 6 SquashPDP2.5PctCT.RDF 22 6 ChineseNapaCabbage.RDF 23 6 ChineseMustardCabbage.RDF 24 6 BrusselsFT10PctCT.RDF 25 6 AppleJuicePDP15pct.RDF 26 6 GrapeJuicePDP10pct.RDF 2 7 6 GuavaFT 1 0 0pct.RDF

EPA Crop Commodity Name Def Res Adj.Factors RDL Comment Code Grp (ppm) #1 #2 Pntr

-------- ---- ------------------------------- ---------- ------ ------ --- ------- 050106 10 5A Broccoli 3.000000 1.000 1.000 7 05010611 5A Broccoli

- babyfood 3.000000 1.000 1.000 7 05010620 5A Broccoli, Chinese 3.000000 1.000 1.000 05010640 5A Brussels sp routs 3.000000 1.000 1.000 24 05010690 5A Cabbage 3.000000 1.000 1.000 14 05010710 5A Cabbage, Chinese, napa 3.000000 1.000 1.000 22 05010720 5A Cabbage, Chinese, mustard 3.000000 1.000 1.000 23 05010830 5A Cauliflower 3.000000 1.000 1.000 7 05011960 5A Kohlrabi 3.000000 1.000 1.000

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 13 of 24 06012570 6A Pea, edible podded, succulent 0.020000 1.0 00 1.000 06022550 6B Pea, succulent 0.020000 1.000 1.000 06022551 6B Pea, succulent

- babyfood 0.020000 1.000 1.000 06022590 6B Pea, pigeon, succulent 0.020000 1.000 1.000 08001480 8 Eggplant 1.000000 1.000 1.000 08002340 8 Okra 1.000000 1.000 1.000 08002700 8 Pepper, bell 1.000000 1.000 1.000 08002701 8 Peppe r, bell

- babyfood 1.000000 1.000 1.000 08002710 8 Pepper, bell, dried 1.000000 1.000 1.000 08002711 8 Pepper, bell, dried

- babyfood 1.000000 1.000 1.000 08002720 8 Pepper, nonbell 1.000000 1.000 1.000 08002721 8 Pepper, nonbell

- babyfood 1.000000 1.000 1.000 08002730 8 Pepper, nonbell, dried 1.000000 1.000 1.000 08003740 8 Tomatillo 1.000000 1.000 1.000 08003750 8 Tomato 1.000000 0.830 1.000 19 08003751 8 Tomato

- babyfood 1.000000 0.830 1.000 19 08003760 8 Tomato, paste 1.000000 0.300 0.100 08003761 8 Tomato, paste

- babyfood 1.000000 0.300 0.100 08003770 8 Tomato, puree 1.000000 0.830 0.100 08003771 8 Tomato, puree

- babyfood 1.000000 0.830 0.100 08003780 8 To mato, dried 1.000000 11.870 0.100 08003781 8 Tomato, dried

- babyfood 1.000000 11.870 0.100 08003790 8 Tomato, juice 1.000000 0.050 1.000 19 09010750 9A Cantaloupe 0.500000 0.020 1.000 09010800 9A Casaba 0.500000 0.020 1.000 09011870 9A Honeydew melon 0.500000 0.020 1.000 09013990 9A Watermelon 0.500 000 1.000 1.000 17 09014000 9A Watermelon, juice 0.500000 1.000 1.000 17 09020210 9B Balsam pear 0.500000 1.000 1.000 09020880 9B Chayote, fruit 0.500000 1.000 1.000 09021020 9B Chinese waxgourd 0.500000 1.000 1.000 09021350 9B Cucumber 0.500000 1.000 1.000 20 09023080 9B Pumpkin 0.500000 1.000 1.000 09023090 9B Pumpkin, seed 0.500000 1.000 1.000 09023560 9B Squash, summer 0.500000 1.000 1.000 21 09023561 9B Squash, summer

- babyfood 0.500000 1.000 1.000 21 09023570 9B Squas h, winter 0.500000 1.000 1.000 21 09023571 9B Squash, winter

- babyfood 0.500000 1.000 1.000 21 10001060 10 Citrus citron 2.000000 1.000 1.000 10001070 10 Citrus hybrids 2.000000 1.000 1.000 10001080 10 Citrus, oil 75.000000 1.000 1.000 10001800 10 Grapefruit 2.000000 1.000 1.000 11 10001810 10 Grapefruit, juice 2.000000 0.060 1.000 11 10001970 10 Kumquat 2.000000 1.000 1.000 10001990 10 Lemon 2.000000 1.000 1.000 10002000 10 Lemon, juice 2.000000 0.060 1.000 10002001 10 Lemon, juice

- babyfood 2.000000 0.060 1.000 10002010 10 Lemon, peel 2.000000 2.600 1.000 10002060 10 Lime 2.000000 1.000 1.000 10002070 10 Li me, juice 2.000000 0.060 1.000 10002071 10 Lime, juice

- babyfood 2.000000 0.060 1.000 10002400 10 Orange 2.000000 1.000 1.000 8 10002410 10 Orange, juice 2.000000 0.060 1.000 8 10002411 10 Orange, juice

- babyfood 2.000000 0.060 1.000 8 10002420 10 Orange, peel 2.000000 2.600 0.350 10003070 10 Pummelo 2.000 000 1.000 1.000 10003690 10 Tangerine 2.000000 1.000 1.000 16 10003700 10 Tangerine, juice 2.000000 0.060 1.000 16 11000070 11 Apple, fruit with peel 5.000000 1.000 1.000 1 11000080 11 Apple, peeled fruit 5.000000 1.000 1.000 1 11000081 11 Apple, peeled fruit

- babyfood 5.000000 1.000 1.000 1 11000090 11 Apple, dried 0.770000 8.000 0.150 11000091 11 Apple, dried

- babyfood 0.770000 8.000 0.150

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 14 of 24 11000100 11 Apple, juice 5.000000 1 .0 0 0 1.000 25 11000101 11 Apple, juice

- babyfood 5.000000 1 .0 0 0 1.000 25 11000110 11 Apple , sauce 5.000000 1.000 1.000 1 11000111 11 Apple, sauce

- babyfood 5.000000 1.000 1.000 1 11001290 11 Crabapple 5.000000 1.000 1.000 11002100 11 Loquat 5.000000 1.000 1.000 11002660 11 Pear 5.000000 1.000 1.000 2 11002661 11 Pear

- babyfood 5.000000 1.000 1.000 2 11002670 11 Pear, dried 0.880000 6.250 0.100 11002680 11 Pear, juice 5.000000 1.000 1.000 2 11002681 11 Pear, juice

- babyfood 5.000000 1.000 1.000 2 11003100 11 Quince 5.000000 1.000 1.000 12000120 12 Apricot 1.400000 1.000 1.000 13 12000121 12 Apricot

- babyfood 1.400000 1.000 1.000 13 12000130 12 Apricot, dried 0.740000 6.000 0.025 12000140 12 Ap ricot, juice 1.400000 1.000 1.000 13 12000141 12 Apricot, juice

- babyfood 1.400000 1.000 1.000 13 12000900 12 Cherry 5.000000 1.000 1.000 4 12000901 12 Cherry

- babyfood 5.000000 1.000 1.000 4 12000910 12 Cherry, juice 5.000000 1.500 1.000 4 12000911 12 Cherry, juice

- babyfood 5.000000 1.500 1.000 4 12002300 12 Nectarine 1.400 000 1.000 1.000 5 12002600 12 Peach 1.400000 1.000 1.000 5 12002601 12 Peach

- babyfood 1.400000 1.000 1.000 5 12002610 12 Peach, dried 0.740000 7.000 0.025 12002611 12 Peach, dried

- babyfood 0.740000 7.000 0.025 12002620 12 Peach, juice 1.400000 1.000 1.000 5 12002621 12 Peach, juice

- babyfood 1.400000 1.000 1.000 5 12002850 12 Plum 1.400000 1.000 1.000 6 12002851 12 Plum

- babyfood 1.400000 1.000 1.000 6 12002860 12 Plum, prune, fresh 1.400000 1.000 1.000 6 12002861 12 Plum, prune, fresh

- babyfood 1.400000 1.000 1.000 6 12002870 12 Plum, prune, dried 1.400000 2.600 1.000 6 12002871 12 Plum, prune, dried

- babyfood 1.400000 2.600 1.000 6 12002880 12 Plum, prune, juice 1.400000 1.400 1.000 6 12002881 12 Plum, prune, juice

- babyfood 1.400000 1.400 1.000 6 13010550 13A Blackberry 12.000000 1.000 1.000 12 13010560 13A Blackberry, juice 12.000000 1.000 1.000 12 13010561 13A Blackberry, juice

- babyfood 12.000000 1.000 1.000 12 13010580 13A Boysenberry 12.000000 1.000 1.000 13011420 13A Dewberry 12.000000 1.000 1.000 13012080 13A Loganberry 12.000000 1.000 1.000 13013200 13A Raspberry 12.000000 1.000 1.000 12 13013201 13A Raspberry

- babyfood 12.000000 1.000 1.000 12 13013210 13A Ra spberry, juice 12.000000 1.000 1.000 12 13013211 13A Raspberry, juice

- babyfood 12.000000 1.000 1.000 12 13020570 13B Blueberry 3.000000 1.000 1.000 9 13020571 13B Blueberry

- babyfood 3.000000 1.000 1.000 9 13021360 13B Currant 3.000000 1.000 1.000 13021370 13B Currant, dried 3.000000 1.000 1.000 13021490 13B Elderberry 3.000 000 1.000 1.000 13021740 13B Gooseberry 3.000000 1.000 1.000 13021910 13B Huckleberry 3.000000 1.000 1.000 9 14000030 14 Almond 0.100000 1.000 1.000 14000031 14 Almond

- babyfood 0.100000 1.000 1.000 14000040 14 Almond, oil 0.100000 1.000 1.000 14000041 14 Almond, oil

- babyfood 0.100000 1.000 1.000 14000590 14 Brazil nut 0.100000 1.000 1.000 14000680 14 Butternut 0.100000 1.000 1.000 14000810 14 Cashew 0.100000 1.000 1.000 14000920 14 Chest nut 0.100000 1.000 1.000 14001550 14 Filbert 0.100000 1.000 1.000 14001560 14 Filbert, oil 0.100000 1.000 1.000

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 15 of 24 14001850 14 Hickory nut 0.100000 1.000 1.000 14002130 14 Macadamia nut 0.100000 1.000 1.000 14002690 14 Pecan 0.100000 1.000 1.000 14002820 14 Pistachio 0.100000 1.000 1.000 14003910 14 Walnut 0.100000 1.000 1.000 21000440 M Beef, meat 0.010000 1.000 1.000 21000441 M Beef, meat

- babyfood 0.010000 1.000 1.000 21000450 M Beef, meat, dried 0.010000 1.920 1.000 21000460 M Beef, meat byproducts 0.010000 1.000 1.000 21000461 M Beef, meat byproducts

- babyfood 0.010000 1.000 1.000 21000470 M Be ef, fat 0.050000 1.000 1.000 21000471 M Beef,fat

- babyfood 0.050000 1.000 1.000 21000480 M Beef, kidney 0.010000 1.000 1.000 21000490 M Beef, liver 0.010000 1.000 1.000 21000491 M Beef, liver

- babyfood 0.010000 1.000 1.000 23001690 M Goat, meat 0.010000 1.000 1.000 23001700 M Goat, meat byproducts 0.010 000 1.000 1.000 23001710 M Goat, fat 0.050000 1.000 1.000 23001720 M Goat, kidney 0.010000 1.000 1.000 23001730 M Goat, liver 0.010000 1.000 1.000 24001890 M Horse, meat 0.010000 1.000 1.000 26003390 M Sheep, meat 0.010000 1.000 1.000 26003391 M Sheep, meat

- babyfood 0.010000 1.000 1.000 26003400 M Sheep, meat byproducts 0.010000 1.000 1.000 26003410 M Sheep, fat 0.050000 1.000 1.000 26003411 M Sheep, fat

- babyfood 0.050000 1.000 1.000 26003420 M Sheep , kidney 0.010000 1.000 1.000 26003430 M Sheep, liver 0.010000 1.000 1.000 27002220 D Milk, fat 0.050000 1.000 1.000 27002221 D Milk, fat

- baby food/in fant for 0.050000 1.000 1.000 40000930 P Chicken, meat 0.050000 1.000 1.000 40000931 P Chicken, meat

- babyfood 0.050000 1.000 1.000 40000940 P Chicken, liver 0.050000 1.000 1.000 40000950 P Chicken, meat byproducts 0.050000 1.000 1.000 40000951 P Chicken, meat byproducts

- babyfoo 0.050000 1.000 1.000 40000960 P Chicken, fat 0.050000 1.000 1.000 40000961 P Chicken, fat

- babyfood 0.050000 1.000 1.000 40000970 P Chicken, skin 0.050000 1.000 1.000 40000971 P Chicken, skin

- babyfood 0.050000 1.000 1.000 50003820 P Tu rkey, meat 0.050000 1.000 1.000 50003821 P Turkey, meat

- babyfood 0.050000 1.000 1.000 50003830 P Turkey, liver 0.050000 1.000 1.000 50003831 P Turkey, liver

- babyfoo d 0.050000 1.000 1.000 50003840 P Turkey, meat byproducts 0.050000 1.000 1.000 50003841 P Turkey, meat byproducts

- babyfood 0.050000 1.000 1.000 50003850 P Turkey, fat 0.050 000 1.000 1.000 50003851 P Turkey, fat

- babyfood 0.050000 1.000 1.000 50003860 P Turkey, skin 0.050000 1.000 1.000 50003861 P Turkey, skin

- babyfood 0.050000 1.000 1.000 60003010 P Poultry, other, meat 0.050000 1.000 1.000 60003020 P Poultry, other, liver 0.050000 1.000 1.000 60003030 P Poultry, other, meat byproducts 0.050000 1.000 1.000 60003040 P Poultry, other, fat 0.050000 1.000 1.000 60003050 P Poultry, other, skin 0.050000 1.000 1.000 70001450 P Egg, whole 0.050000 1.000 1.000 70001451 P Egg, whole

- babyfood 0.050000 1.000 1.000 70001460 P Egg, white 0.050000 1.000 1.000 70001461 P Egg, white (solids)

- babyfood 0.050000 1.000 1.000 70001470 P Egg, yolk 0.050000 1.000 1.000 70001471 P Egg, yolk

- babyfood 0.050000 1.000 1.000 86010000 O Water, direct, all sources 0.010300 1.000 1.000 86020000 O Water, indirect, all sources 0.010300 1.000 1.000 95000010 O Acerola 1.500000 1.000 1.000

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 16 of 24 95000200 O Avocado 1.000000 1.000 1.000 95000740 O Canistel 1.000000 1.000 1.000 95000890 O Cherimoya 1.000000 1.000 1.000 95001280 O Cottonseed, oil 3.000000 1.000 0.025 95001281 O Cottonseed, oil

- babyfood 3.000000 1.000 0.025 95001750 O Gr ape 5.000000 1.000 1.000 3 95001760 O Grape, juice 5.000000 1

. 00 0 1.000 26 95001761 O Grape, juice

- babyfood 5.000000 1

. 00 0 1.000 26 95001770 O Grape, leaves 5.000000 1.000 0.100 95001780 O Grape, raisin 5.000000 1.540 1.000 3 95001790 O Grape, wine and sherry 5.000000 0.003 1.000 3 95001830 O Guava 1.500 000 1.000 1.000 27 95001831 O Guava

- babyfood 1.500000 1.000 1.000 27 95001920 O Jaboticaba 1.500000 1.000 1.000 95002090 O Longan 3.000000 1.000 1.000 95002110 O Lychee 3.000000 1.000 1.000 95002120 O Lychee, dried 3.000000 1.000 1.000 95002150 O Mango 1.000000 1.000 1.000 15 95002151 O Mango

- babyfood 1.000000 1.000 1.000 15 95002160 O Mango, dried 1.000000 1.000 1.000 95002170 O Mango, juice 1.000000 1.000 1.000 15 95002171 O Mango , juice

- babyfood 1.000000 1.000 1.000 15 95002350 O Olive 5.000000 1.000 1.000 18 95002360 O Olive, oil 5.000000 1.000 1.000 95002450 O Papaya 1.000000 1.000 1.000 15 95002451 O Papaya

- babyfood 1.000000 1.000 1.000 15 95002460 O Papaya, dried 1.000000 1.800 1.000 95002470 O Papaya, juice 1.000000 1.500 1.000 15 95002520 O Passionfruit 1.500000 1.000 1.000 27 95002521 O Passionfruit

- babyfood 1.500000 1.000 1.000 27 95002530 O Passionfruit, juice 1.500000 1.000 1.0 00 27 95002531 O Passionfruit, juice

- babyfood 1.500000 1.000 1.000 27 95002630 O Peanut 0.010000 1.000 1.000 95002640 O Peanut, butter 0.010000 1.890 1.000 950026 50 O Peanut, oil 0.010000 4.000 1.000 95003330 O Sapote, Mamey 1.000000 1.000 1.000 95003460 O Soursop 1.000000 1.000 1.000 95003510 O Spanish lim e 3.000000 1.000 1.000 95003580 O Starfruit 1.500000 1.000 1.000 95003590 O Strawberry 2.000000 1.000 1.000 10 95003591 O Strawberry

- babyfood 2.000000 1.000 1.000 10 95003600 O Strawberry, juice 2.000000 1.000 1.000 10 95003601 O Strawberry, juice

- babyfood 2.000000 1.000 1.000 10 95003610 O Sugar apple 1.000000 1.0 00 1.000 95003720 O Tea, dried 2.000000 1.000 1.000 95003730 O Tea, instant 2.000000 1.000 1.000

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 17 of 24 

### Attachment 2: Results of Acute Dietary Exposure A ssessment
DEEM

- FC ID Version 2.0 3 (1994

- 98 data) Residue file: FenpropAcutePDP.R98 Residue file dated: 0 6

- 10

- 2012/1 0 : 40 : 5 1 /8 Analys is Dates: 0 6

- 10

- 2012/1 0 :5 3 : 47 (Adults)

0 6

- 10

- 2012/1 0 : 48 : 49 (Infants and Children) Adjustment factor #2 used. Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10
aPAD for Youth and Adults ( >6 years of Age): 0.05 mg/kg/day aPAD for Infants and Children (6 years of age and under) : 0.017 mg/kg/day

=============================================================================== Summary calculations (per capita):
95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD MOE Exposure % aRfD MOE Ex posure % aRfD MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- -------- U.S. Population: 0.001758 3.52 2844 0.003745 7.49 1335 0.009489 18.98 526

All infants: 0.002466 14.51 2027 0.004525 26.62 1105 0.011457 67.40 436 Children 1

- 2 yrs: 0.002652 15.60 1885 0.006247 36.75 800 0.015343 90.26 325 Children 3

- 5 yrs: 0.002547 14.98 1963 0.005918 34.81 844 0.016488 96.99 303

Children 6

- 12 yrs: 0.001727 3.45 2894 0.004466 8.93 1119 0.013489 26.98 370 Youth 13

- 19 yrs: 0.001388 2.78 3603 0.002998 6.00 1667 0.009290 18.58 538 Adults 20

- 49 yrs: 0.001723 3.45 2901 0.003557 7.11 1405 0.007920 15.84 631 Adults 50+ yrs: 0.001578 3.16 3167 0.003327 6.65 1503 0.008093 16.19 617 Females 13

- 49 yrs: 0.001648 3.30 3033 0.003340 6.68 1496 0.008476 16.95 589

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 18 of 24 

### Attachment 3. Residue Inputs for Individual Commodities

Commodity Blending Class. Data Source RDF No. Max. %CT Broccoli (and baby food) NB/PB PDP (Broccoli: 2007, 2008 ) 7 2.5 Broccoli, Chinese NB Tolerance

- 100 Brussels Sprouts PB FT (Cabbage) 24 10 Cabbage NB/PB FT (Cabbage) 14 2.5 Cabbage, Chinese napa NB/PB FT (Cabbage) 22 100 Cabbage, Chinese mustard NB/PB PDP (Broccoli : 200 7 , 200 8 ) 23 100
Cauliflower NB/PB PDP (Broccoli: 200 7 , 200 8 ) 7 2.5
Kohlrabi NB Tolerance

- 100 Pea, succulent PB Tolerance

- 100 Eggplant NB/PB Tolerance

- 100 Okra NB/PB Tolerance

- 100 Pepper, Bell (and baby food) NB/PB Tolerance

- 100 Pepper, Bell

- Dried (and baby food) B Tolerance

- 100 Pepper, Nonbell (and baby food) NB/PB Tolerance

- 100 Pepper, Nonbell

- Dried B Tolerance

- 100 Tomatillo NB/PB Tolerance

- 100 Tomato (and baby food) NB/PB FT (Tomato) 19 10 Tomato paste B Tolerance

- 10 Tomato puree B Tolerance

- 10 Tomato

– dried B Tolerance

- 10 Tomato juice PB FT (Tomato) 19 10 Cantaloupe NB/PB Tolerance

- 100 Casaba NB Tolerance

- 100 Honeydew melon NB/PB Tolerance

- 100 Watermelon and Watermelon juice NB PDP (Watermelon : 2010 ) 17 2.5
Balsam Pear NB Tolerance

- 100 Chayote, fruit NB Tolerance

- 100 Chinese Waxgourd NB Tolerance

- 100 Cucumber NB/PB FT (Cucumber) 20 2.5 Pum pkin NB/PB Tolerance

- 100 Pum pkin seed B Tolerance

- 100 Squash, summer (and baby food) NB/PB PDP (Squash : 2007, 2008 ) 21 2.5 Squash, winter (and baby food) NB/PB PDP (Squash: 2007, 2008) 21 2.5 Citrus citron NB Tolerance

- 100 Citrus hybrids NB Tolerance

- 100 Citrus oil B Tolerance

- 100 Grapefruit and grapefruit juice NB/PB FT (Grapefruit) 11 35 Kumquat NB Tolerance

- 100 Lemon (fruit, juice, juice baby food, and peel) NB/PB Tolerance

- 100 Lime (fruit and juice) PB Tolerance

- 100 Orange (fruit, juice, and juice baby food) NB/PB PDP (Orange : 2009, 2010 ) 8 35 Orange peel PB Tolerance

- 35 Pummelo NB Tolerance

- 100 Tangerine (fruit and juice) NB/PB PDP (Orange : 2009, 2010 ) 16 15 Apple (fruit and fruit baby food) NB/PB PDP (Apple : 2009, 2010 ) 1 15

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 19 of 24 

### Commodity Blending Class. Data Source RDF No. Max. %CT Apple

– dried (and baby food) B Avg FT (Apple , 0.77 ppm)

- 15 Apple juice (and baby food) PB PDP (Apple Juice : 2007, 2008 ) 25 15 Apple sauce (and baby food) PB PDP (Apple: 2009, 2010) 1 15 Crabapple NB Tolerance

- 100 Loquat NB Tolerance

- 100 Pear (and baby food) NB/PB PDP (Pear : 2008, 2009) 2 10 Pear

– dried B Avg FT (Pear)

- 10 Pear juice (and baby food) PB PDP (Pear: 2008, 2009) 2 10 Quince NB Tolerance

- 100 Apricot (and baby food) NB/PB FT (Peach) 13 2.5 Apricot

- dried B Avg FT (Peach , 0.74 ppm)

- 2.5 Apricot juice (and baby food) PB FT (Peach) 13 2.5 Cherry (and baby food) PB FT (Cherry) 4 5 Cherry juice (and baby food) PB FT (Cherry) 4 5 Nectarine NB FT (Peach) 5 2.5 Peach (and baby food) NB/PB FT (Peach) 5 2.5 Peach

- dried (and baby food) B Avg FT (Peach , 0.74 ppm)

- 2.5 Peach juice (and baby food) PB FT (Peach) 5 2.5 Plum (and baby food) NB/PB FT (Plum) 6 2.5 Plum, prune, fresh (and baby food) NB/PB FT (Plum) 6 2.5 Plum, prune

– dried (and baby food) PB FT (Plum) 6 2.5 Plum, prune, juice (and baby food) NB/PB FT (Plum) 6 2.5 Blackberry PB FT (Black/Raspberry) 12 100 Blackberry juice (and baby food) PB FT (Black/Raspberry) 12 100 Boy senberry PB Tolerance

- 100 Dew berry PB Tolerance

- 100 Loganberry PB Tolerance

- 100 Raspberry (and baby food) PB FT (Black/Raspberry) 12 100 Raspberry juice (and baby food) PB FT (Black/Raspberry) 12 100 Blueberry (and baby food) PB PDP (Blueberry : 2007, 2008 ) 9 2.5
Currant and Currant

– dried PB Tolerance

- 100 Elderberry PB Tolerance

- 100 Gooseberry PB Tolerance

- 100 Huckleberry PB PDP (Blueberry: 2007, 2008) 9 100 Tree nuts (almond (and baby food), brazil nut, cashew, chestnut, filbert, hickory nut, macad amia nut, pecan, pistachio, walnut) PB Tolerance

- 100

Tree nuts (butter nut) NB Tolerance

- 100 Almond oil (and baby food) B Tolerance

- 100 Filbert oil B Tolerance

- 100 Beef (meat, meat

- babyfood, meat byproducts, meat by products

- babyfood, kidney, liver, liver

babyfood) - Recommended Reassessed Tolerance (0.01 ppm) - 100

Beef, meat

– dried

- Recommended Tol . (0.01)

- 100 Beef fat (and baby food)

- Recommended Tol. (0.05)

- 100 Goat (meat, meat byproducts, kidney, liver)

- Recommended Tol. (0.01)

- 100 Goat fat

- Recommended Tol. (0.05)

- 100

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 20 of 24 

### Commodity Blending Class. Data Source RDF No. Max. %CT Horse meat

- Recommended Tol. (0.01)

- 100 Sheep (meat, meat babyfood, meat byproducts, kidney, liver) - Recommended Reassessed Tolerance (0.01 ppm) - 100 Sheep fat (and baby food)

- Recommended Tol. (0.05)

- 100 Milk fat (and baby food)

- Recommended Tol. (0.05)

- 100 Chicken, Turkey, Poultry, other (all food forms)

- Tolerance

- 100 Egg

- whole, white, yolk (and baby food)

- Tolerance

- 100 Water, direct and indirect, all sources

- EFED Water Memo

- - Acerola NB Tol. (proposed)

- 100 Avocado NB Tolerance

- 100 Canistel NB Tolerance

- 100 Cherimoya NB Tolerance

- 100 Cottonseed oil (and baby food) B Tolerance

- 2.5 Grape PB PDP (Grape : 2009, 2010 ) 3 10 Grape Juice (and baby food) PB PDP (Grape Juice : 2008 ) 26 10 Grape Leaves PB Tolerance

- 10 Grape, raisin Grape, wine and sherry PB PDP (Grape: 2009, 2010) 3 10 Guava (and baby food) NB/PB FT (Guava) 27 100 Jaboticaba NB Tol. (proposed)

- 100 Longan NB Tol. (proposed)

- 100 Lychee NB Tol. (proposed)

- 100 Lychee

- dried B Tol. (proposed)

- 100 Mango (and baby food) NB/PB FT (Avocado) 15 100 Mango, dried NB Tolerance

- 100 Mango, juice (and baby food) PB Tolerance 15 100 Olive PB FT (Olive) 18 100 Olive Oil B Tolerance

- 100 Papaya (and baby food) NB/PB FT (Avocado) 15 100 Papaya, dried B Tolerance

- 100 Papaya, juice PB FT (Avocado) 15 100 Passionfruit NB FT (Guava) 27 100 Passionfruit, juice (and baby food) PB FT (Guava) 27 100 Peanut, Peanut Butter, and Peanut Oil B Tolerance

- 100 Sapote, mamey NB Tolerance

- 100 Soursop NB Tol. (proposed)

- 100 Spanish Lime NB Tol. (proposed)

- 100 Starfruit NB Tol. (proposed)

- 100 Straw berry (and baby food) Straw berry Juice (and baby food) PB PDP (Straw berry : 2008, 2009 ) 10 50 Sugar Apple NB Tol. (proposed)

- 100 Tea, dried and instant B Tol. (proposed)

- 100

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 21 of 24 

### Attachment 4: Residue Distribution Files
RDF #1 PDP Data
Apples 15%CT TotalZ = 1251 TotalLOD = 176 LODRES = 0.0079 0.29 0.19 0.14 0.11 0.1 0.1 0.1 0.098 0.097 0.097 0.089 0.088 0.087 0.084 0.076 0.069 0.064 0.062 0.026 0.026 0.20 0.19 0.19 0.17 0.17 0.16 0.16 0.15 0.14 0.068 0.066 0.063 0.062 0.06 0.06 0.056 0.052 0.026 0.026 0.026 0.026 0.026 0.026 0.015 0.015 

### RDF #2

PDP Data

Pears PDP Data 10%CT TotalZ = 1336 TotalLOD = 145 LODRES = 0.0185 0.61 0.52 0.47 0.062



### RDF #4 Field Trial Data
Cherry FT Data 5%CT TotalNZ = 12 TotalZ = 228
1.83 1.97 2.02 1.60 1.44 1.43 3.18 3.33 1.59 1.43 3.53 3.23



### RDF #6 Field Trial Data
Plum FT Data 2.5%CT TotalNZ = 11 TotalZ = 429
0.51 0.58 0.23 0.23 0.29 0.21 0.37 0.27 0.24 0.20 0.18 

### RDF #3 PDP Data
Grape PDP Data 10%CT TotalZ = 1340 TotalLOD = 51 LODRES = 0.007885 

### RDF #5

Field Trial Data

Peach Field Trial Data 2.5%CT TotalNZ = 20 TotalZ = 780
0.66 0.66 0.76 0.63 0.56 0.73 0.91 1.11 1.05 1.01 0.69 0.72 0.79 0.67 0.61 0.54 0.39 0.49 1.00 0.84



### RDF #7 PDP Data

Broccoli 2.5%CT TotalZ = 1258 TotalLOD = 32 LODRES = 0.0078



### RDF #8 PDP Data Orange PDP Data 35%CT TotalZ = 913 TotalLOD = 491 LODRES = 0.007051 

### RDF #9

PDP Data

Blueberries PDP Data 2.5%CT TotalZ = 1401 TotalLOD = 11 LODRES = 0.007573 1.3 1.2 0.87 0.59 0.43 0.32 0.27 0.20 0.19 0.14 0.14 0.092 0.077 0.074 0.065 0.060 0.026 0.026 0.026 0.026 0.38 0.37 0.29 0.24 0.17 0.21 0.20 0.19 0.17 0.16 0.15 0.14 0.13 0.12 0.12 0.12 0.11 0.11 0.11 0.11 0.096 0.094 0.092 0.086 0.083 0.066 0.066 0.065 0.065 0.065 0.060 0.060 0.059 0.057 0.057 0.056 0.053 0.053 0.053 0.052 0.050 0.048 0.047 0.046 0.045 0.043 0.040 0.038 0.035 0.034 0.031 0.031 0.029 0.028 0.028 0.024 0.021 0.020 0.020 0.020 0.015

0.015 0.015 0.015 0.015 0.015 0.015 0.57 0.16 0.16 0.14 0.12 0.12 0.11 0.098 0.09 0.089 0.081 0.075 0.07 0.055 0.053 0.053 0.05 0.043 0.043 0.04 0.038 0.036 0.036 0.033 0.033 0.031 0.031 0.028 0.015 0.015 0.015 0.015 0.015 0.015 0.015 0.015

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 22 of 24 

### RDF #10 PDP Data

Strawberries 50%CT TotalZ = 742 TotalLOD = 595 LODRES = 0.006634 

### RDF #11 Field Trial Data
Grapefruit FT Data 35%CT TotalNZ = 14 TotalZ = 26
0.57 0.40 0.38 0.36 0.36 0.35 0.32 0.27 0.23 0.18 0.18 0.16 0.13 0.11



### RDF #12 Field Trial Data Caneberry FT Data 100%CT TotalNZ = 14 TotalZ = 0
7.1 6.1 5.5 4.7 4.1 3.3 2.3 1.9 1.8 1.8 1.7 1.4 1.2 1.0 

### RDF #13

Field Trial Data
Apricot (Peach FT Data) 2.5%CT TotalNZ = 20 TotalZ = 780
0.66 0.66 0.76 0.63 0.56 0.73 0.91 1.11 1.05 1.01 0.69 0.72 0.79 0.67 0.61 0.54 0.39 0.49 1.00 0.84



### RDF #14 Field Trial Data
Cabbage FT Data 2.5%CT TotalNZ = 12 TotalZ = 468
2.8 2.7 1.3 1.2 0.67 0.45 0.41 0.40 0.30 0.30 0.24 0.20 

### RDF #15 Field Trial Data
Papaya (Avocado FT Data) 100%CT TotalNZ = 12 TotalZ = 0
0.58 0.52 0.51 0.45 0.42 0.42 0.40 0.38 0.32 0.31 0.20 0.14



### RDF #16 PDP Data Tangerines (Orange PDP Data) 15%CT TotalZ = 1193 TotalLOD = 211 LODRES = 0.007051



### RDF #17 PDP Data

Watermelon PDP Data 2.5%CT TotalZ = 362 TotalLOD = 9 LODRES = 0.0045 

### RDF #18

Field Trial Data

Olive FT Data 100%CT TotalNZ = 6 TotalZ = 0
3.7 3.4 2.3 2.1 2.0 1.8



### RDF #19 Field Trial Data

Tomato FT Data 10%CT TotalNZ = 32 TotalZ = 288
0.16 0.18 0.10 0.09 0.07 0.05 0.08 0.08 0.21 0.29 0.23 0.06 0.20 0.03 0.24 0.18 0.22 0.32 0.29 0.30 0.46 0.64 0.04 0.06 0.10 0.12 0.18 0.20 0.07 0.08 0.15 0.21 1.3 0.61 0.42 0.41 0.41 0.33 0.32 0.29 0.28 0.27 0.26 0.26 0.24 0.21 0.21 0.19 0.18 0.18 0.17 0.17 0.16 0.14 0.14 0.14 0.13 0.13 0.13 0.13 0.12 0.12 0.12 0.098 0.097 0.096 0.094 0.092 0.088 0.086 0.084 0.082 0.081 0.075 0.075 0.074 0.071 0.070 0.065 0.063 0.061 0.060 0.055 0.054 0.054 0.053 0.044

0.043 0.042 0.040 0.038 0.036 0.032 0.032 0.032 0.03 0.028 0.028 0.028 0.026 0.024 0.023 0.022 0.02 0.016 0.015 0.015 0.015 0.015 0.015 0.014 0.014 0.011 0.011 0.01 0.01 1.7 1.2 1.1 0.76 0.73 0.73 0.61 0.57 0.47 0.37 0.37 0.35 0.34 0.34 0.31 0.27 0.23 0.22 0.22 0.21 0.20 0.20 0.20 0.18 0.17

0.17 0.16 0.16 0.15 0.15 0.14 0.14 0.14 0.11 0.11 0.10 0.092 0.091 0.090 0.089 0.083 0.074 0.072 0.062 0.062 0.061 0.056 0.053 0.044 0.042 0.042 0.040 0.039 0.036 0.036 0.032 0.030 0.028 0.021 0.020 0.015 0.015 0.015 0.015

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 23 of 24 

### RDF #20 Field Trial Data

Cucumber FT Data 2.5%CT TotalNZ = 20 TotalZ = 780
0.047 0.055 0.036 0.042 0.033 0.034 0.01 0.01 0.01 0.011 0.010 0.01 0.01 0.01 0.01 0.01 0.027 0.020 0.01 0.01



### RDF #21 PDP Data Squash PDP Data 2.5%CT TotalZ = 1264 TotalLOD = 32 LODRES = 0.01984 

### RDF #22

Field Trial Data
Chinese Napa Cabbage (Cabbage FT Data) 100%CT TotalNZ = 12 TotalZ = 0
2.8 2.7 1.3 1.2 0.67 0.45 0.41 0.40 0.30 0.30 0.24 0.20



### RDF #23 PDP Data
Chinese Mustard Cabbage (Broccoli PDP) 100%CT TotalZ = 0 TotalLOD = 32 LODRES = 0.0078 

### RDF #24

Field Trial Data
Brussels Sprouts (Cabbage FT Data) 10%CT TotalNZ = 12 TotalZ = 108
2.8 2.7 1.3 1.2 0.67 0.45 0.41 0.40 0.30 0.30 0.24 0.20 

### RDF #25

PDP Data
Apple Juice PDP Data 15%CT TotalZ = 629 TotalLOD = 111 LODRES = 0.01975 

### RDF #26

PDP Data
Grape Juice PDP Data 10%CT TotalZ = 670 TotalLOD = 75 LODRES = 0.009507



### RDF #27 Field Trial Data
Guava FT Data 100%CT TotalNZ = 6 TotalZ = 0
1.09 0.949 0.608 0.577 0.566 0.484

### Fenpropathrin Dietary Exposure and Risk Assessment DP Number: D402246

Page 24 of 24 **May 24, 2012 Screening**  **Level Estimates of Agricultural Uses of Fenpropathrin (127901) Sorted Alphabetically**  **(Reporting Timeframe: 2003**

**- 2010)**  **Percent Crop Treated Crop**  **Lbs. A.I. Average**  **Ma xim**  **um 1**  **Almonds 4,000**  **<2.5 <2.5**  **2 Apples**  **10,000 10**  **15 3**  **Apricots*** **<500 <1**  **<2.5 4**  **Avocados*** **<500 <1**  **<2.5 5**  **Blueberries <500**  **<2.5 <2.5**  **6 Broccoli** * **<500 <1**  **<2.5 7**  **Brussels Sprouts*** **<500 <5**  **10 8**  **Cabbage <500**  **<1 <2.5**  **9 Cantaloupes**  **<500 <2.5**  **5 10**  **Cauliflow er**  **<500 <1**  **<2.5 11**  **Cherries 1,000**  **<2.5 5**  **12 Cotton**  **3,000 <1**  **<2.5 13**  **Cucumbers <500**  **<1 <2.5**  **14 Grapefruit**  **4,000 10**  **35 15**  **Grapes 10,000**  **5 10**  **16 Lemons**  **<500 <1**  **<2.5 17**  **Nectarines*** **<500 <2.5**  **<2.5 18**  **Olives*** **<500 <1**  **<2.5 19**  **Oranges 40,000**  **15 35**  **20 Peaches**  **<500 <1**  **<2.5 21**  **Peanuts 1,000**  **<1 <2.5**  **22 Pears**  **1,000 5**  **10 23**  **Peppers 2,000**  **5 10**  **24 Pistachios** * **<500 <1**  **<2.5 25**  **Plums/Prunes 1,000**  **<1 <2.5**  **26 Pumpkin**  **<500 <1**  **<2.5 27**  **Squash <500**  **<1 <2.5**  **28 Strawberries**  **9,000 30**  **50 29**  **Tangelos <500**  **5 10**  **30 Tangerines**  **1,000 10**  **15 31**  **Tomatoes 4,000**  **5 10**  **32 Watermelon**  **<500 <1**  **<2.5** All numbers rounded.

<500 Less than 500 pounds of active ingredient <2.5 Less than 2.5 percent of crop treated <1 Less than 1 percent of crop treated

* Based on CA DPR data only (valid because 80% or more of U.S. acres grown are in California)

SLUA data sources include: USDA

- NASS (United States Department of Agriculture's National Agricultural Statistics Service) Private Pesticide Market Research, California DPR (Department of Pesticide Regulation) These results reflect amalgamated data develop ed by the Agency and are releasable to the public.